Gene BRSK1 (Human)

BRSK1

Species: Human
Alias: KIAA1811, FLJ43009, BRSK1
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 19q13.4,

Classification

Group: CAMK
Family: CAMKL
Subfamily: BRSK

Sequence

Name Sequence Type Origin Length Description Download
BRSK1.kin_dom Protein Kinase Domain Sugen Kinome 252 None Fasta, JSON
BRSK1.AA Protein Sugen Kinome 794 None Fasta, JSON
BRSK1.NA RNA Sugen Kinome 3007 None Fasta, JSON

Protein domain

Protein domains of BRSK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase BRSK1.AA BRSK 50-301 87 1.6e-231 775.42 In-house 1-254 (254) Show / Hide 
Range on Protein: 50-301
Range on HMM: 1-254/254
Sequence Identity: 87% (222 aa)

YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLS--ESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPK
|||||||||||||||||||||.||.||||||.|.||||  ||.||||||||||.|||.||||.|..|||||||||||.||||||||||||||||||||||
YRLEKTLGKGQTGLVKLGVHCVTGKKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPK

EARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPF
|||||||||.||||||||..|||||||||||||||||||.|||||||||||.|..|.||||||||||||||.|||||||.||.|||||||.|||||||||
EARKFFRQIISALDFCHSHNICHRDLKPENLLLDEKNNIKIADFGMASLQVKDMMLHTSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPF

DDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWY
|||||||||||||||||||||||.||||.||||||||.|.||.||..|||||||
DDDNLRQLLEKVKRGVFHMPHFIHPDCQDLLRGMIEVDPDKRISLKEIQKHPWY
Kinase BRSK1.AA CAMKL 50-301 43 1.6e-152 490.16 In-house 1-297 (297) Show / Hide 
Range on Protein: 50-301
Range on HMM: 1-297/297
Sequence Identity: 43% (131 aa)

YRLEKTLGKGQTGLVKLGVH-CITGQKVAIKIVNREKLS--------------ESVLMKVEREIAILKLIE---HPHVLKLHDVYENKKY------LYLV
||..||||||  | |||..|  .||.||||||....|..              ||.. ...|||.|.|..    ||.. ||..|.|....      .|||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

LEHVSGGE--LFDYLVKK----GRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKN--NIRIADFGMASLQV-G----DSLLETSCGSPHY
.|..||||  ||||.||.    ||....|||..|||||||...|||  |.|||.||||.||||..  || |.|||.. ..  .    . .|.|.||||.|
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

ACPEVIKG--EKYDGRRADMWSCGVILFALLVGALPFDDD--------NLRQLLEKVKRGVFHMPHF--IPPDCQSLLRGMIEVEPEKRLSLEQIQKHPW
..||...|  ..|||. .|.|||||||.|...|.||||||        |   |..|...| ...|..  .. ||..|.|.| .| |||| ...|| .|||
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

Y
.
M
Kinase BRSK1.AA AMPK 50-301 49 1.5e-146 438.03 In-house 1-254 (254) Show / Hide 
Range on Protein: 50-301
Range on HMM: 1-254/254
Sequence Identity: 49% (125 aa)

YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKL-SESVLMKVEREIAILKLIEHPHVLKLHDVY-ENKKYLYLVLEHVSGGELFDYLVKKGRLTPK
| ..||.|.|  | ||.|.| .||.|||||| |..|. ....  ...||| ||||. |||. .| .|  | .. ...|.|.||||||||| ||.|||. .
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPF
||..|| ||.|... ||   | ||||||||||||...|| |.|||   .     .| |.|||| || ||.| | .| |.  | |||||||.|.| | |||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

DDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWY
||.| ..|  |.| |..  | |. |....|...| .| |.||.. ..| .|||.
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase BRSK1.AA CAMK 55-301 29 2.3e-134 435.68 In-house 1-425 (425) Show / Hide 
Range on Protein: 55-301
Range on HMM: 1-425/425
Sequence Identity: 29% (126 aa)

TLGKGQTGLVKLGVHCITG------------QKVAIKIVNREKLS--------------------------ESVLMKVEREIAILKL-------IEHPHV
|||.|. | |||..|  |.            |||||||....||.                          .. . .|.|||.|.|.       . ||..
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LKLHDVYEN-------------------KKYLYLVL---EHVSGGEL----FDYLVKK---------------GRLTPKEARKFFRQIVSALDFCHSYSI
.||..|||.                   .|..|.|.   |..|||||    |||.|..               ||.| .|||..||||.||...|||  |
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

CHRDLKPENLLLDEK-----------------NNIRIADFGMASLQVG------------------------DSLLETSCGSPHYAC-PEVIKG------
.||||||||.|||..                 ||| |.|||.|    .                        . ...|.||.|.|.. |||..|      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------EKYDGRRADMWSCGVILFALLVGALPFDDD-------------NLRQLLEKVKRGVFH-MPHFIPP-----------------------DCQS
       ..|.|. .|||||||||...|.| .||..|             |...|.||...| ..  |....|                       .|..
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LLRGMIEVEPEKRLSLEQIQKHPWY
|.|.| .|.||||...||. .|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase BRSK1.AA NuaK 50-301 42 7.4e-121 319.59 In-house 1-252 (252) Show / Hide 
Range on Protein: 50-301
Range on HMM: 1-252/252
Sequence Identity: 42% (108 aa)

YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKL-SESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKE
|...||||||  | |||..   ||..|||| . ..|  .|  .... ||| |.  ..|||. . . |.|||  . .|.|  |||||.||. ....|. .|
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE

ARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFD
||.||||||||. .||   ||||||| || |||...|..|||||. ..   . .|.| |||| || ||.. |. | |   | || ||.|...  | .|||
ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFD

DDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWY
 .. ..|   ...| .  |.  | |   | | |  |.|..| ....| .|.| 
GHDFKHLVKQISQGAYYEPC-KPSDACMLIRWMLMVNPRRRATIYDICHHWWV
Kinase BRSK1.AA MARK 50-301 43 1.7e-120 395.49 In-house 1-262 (262) Show / Hide 
Range on Protein: 50-301
Range on HMM: 1-262/262
Sequence Identity: 43% (113 aa)

YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSE-SVLMKVEREIAILKLIEHPHVLKLHDVYE--NKKY-LYLVLEHVSGGELFDYLVKK--GR
|.. ||.|.|  . |||..|  ||.||||||....||..   . .|.|||.|.|...||.. ||..| |  ...  .||..|..|||||.||....  ||
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKN--NIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALL
|. .|||..|||||||. .||| .|.|||.||||.|.||..  || |.|||..     ...|.| ||.| |..||......|||. .|.||.||.|....
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

VGALPFDDDN--LRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWY
.| .|||.|.  . .| .|. ||... |......|..|.. .. | ||.| ..|.| |||| 
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase BRSK1.AA QIK 50-301 44 2.7e-118 399.32 In-house 1-272 (272) Show / Hide 
Range on Protein: 50-301
Range on HMM: 1-272/272
Sequence Identity: 44% (122 aa)

YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGR------
| .|.|.|||  . |||. | || .||||||. ...| |. | |..||..|.|...|||. || .| | ....|.| |  |.||.||||.|.||      
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMV

--------------LTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRAD
              .. .|||. | ||.|| ..||.  | ||||| ||.|||.  || |||||.  .. .. ||.| |||| || ||. .|..||| ..|
NSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVD

MWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWY
 || ||.|..|  |||||| ..| .| ..|  | | .| |.. ||..| | |  |.||.|.. .|| .|.| 
IWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase BRSK1.AA GIN4 94-301 55 3.8e-107 343.37 In-house 81-293 (293) Show / Hide 
Range on Protein: 94-301
Range on HMM: 81-293/293
Sequence Identity: 55% (119 aa)

VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNN-IRIADFG
.|||| |.|||.|| |..|.||.|... |||||| . .||||.|||..|.|  .|| ..||||.  . .||.. ||||||||||||||.|.| |.|||||
IEREIVIMKLISHPNVMRLYDVWETNNDLYLVLEYAEKGELFNYLVDHGPLPEREAIHYFRQIIIGVSYCHAFNICHRDLKPENLLLDHKYNRIKIADFG

MASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDD--NLRQLLEKVKRGVFHMPHF--IPPDCQSLLRGMIEVEPEK
|| |..   |||||||||||| ||.. |  |.|  .|.||||||||||| | ||||..  |.|.|| ||..| ..||    |  . | |.| .. |.|||
MAALETDNKLLETSCGSPHYAAPEIVMGIPYHGFASDVWSCGVILFALLTGHLPFDEEDGNIRKLLLKVQKGKYEMPSDDEISREAQDLIRKILVVDPEK

RLSLEQIQKHPWY
|.   .| |||  
RIKTRDILKHPLI
Kinase BRSK1.AA S_TKc 50-301 36 3.3e-105 356.76 SMART 1-231 (231) Show / Hide 
Range on Protein: 50-301
Range on HMM: 1-231/231
Sequence Identity: 36% (97 aa)

YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSG--GELFDYLVKKGR----
|.. ...|||  | |....|  ||..|||||..          ...|||.|||   ||.. ||.||... ..||.|.|...|  |.||||..|.||    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALL
  ... .||....||..||..|||  |.||||||||.||||  .| |.|||.| .        | ||.|.|  |||.   .|.....|.||||.||. .|
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

VGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQK-------HPWY
.|  ||.  .. ....|..          .|.. ...|.. ...||||..  .. .       ||| 
CGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase BRSK1.AA CAMK1 50-301 38 5.2e-101 294.36 In-house 1-276 (276) Show / Hide 
Range on Protein: 50-301
Range on HMM: 1-276/276
Sequence Identity: 38% (108 aa)

YRLEKTLGKGQTGLVKLGVHCIT---GQKVAIKIVN-REKLSESVL---MKVEREIAILKL---IEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLV
| . |..|.|  . |.|..|  |   |...|||. . .. ....     ...|.||.|.|    | ||.. |....|| ....|||.| |.||||||  |
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

KKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEK-NN--IR--IADFGMASLQVGDS-LLETSCGSPHYACPEVIKG---EKYDGRRADM
.||  | |.||.  .||.||. ..||  |.||||||||||.  | ..  |.  ||||| .    .|. |..| ||.| |  |||...   . ||    ||
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYD-KACDM

WSCGVILFALLVGALPFDDDN-LRQLLEKVKRGVFHMPHF----IPPD-CQSLLRGMIEVEPEKRLSLEQIQKHPWY
||.|||.. ||.|  || |.|   .|.||.|.. . .| .    |       ....|.||.|.||.. ||. .||| 
WSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase BRSK1.AA Pkinase 50-301 31 3.5e-100 343.91 Pfam 1-293 (293) Show / Hide 
Range on Protein: 50-301
Range on HMM: 1-293/293
Sequence Identity: 31% (94 aa)

YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMKVER--EIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGG----ELFDYLV--KK
|......|.|  | |....|  ||..||.||..... ......   |  ||.|.| . ||....|.|..|.|...|.|.|.. ||    .||||.   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GRL--TPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNI----RIADFGMASL--QVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSC
|..  ...|......||...|..||| .|.||||||||.|.|....|    .|.||| | .     .| . | ||.|.|. ||||.| .|.|...|||||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVILFALLVGALPFDDD------NLRQLLEKVKRGVFHMPHFIP---------------------PDCQSLLRGMIEVEPEKRLSLEQIQKHPWY
|.||. .| | .||...      . .|........ .| . . .                     ..|.......... |.||.. ||| .||| 
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase BRSK1.AA MELK 50-301 42 1.1e-92 314.18 In-house 1-254 (254) Show / Hide 
Range on Protein: 50-301
Range on HMM: 1-254/254
Sequence Identity: 42% (108 aa)

YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEA
| . ...| |  . ||| .| .|.|.|||||.....|  . | .|. |.  || ..| |. .|. . | .. ...|.|. .|||.|||.... ||  .|.
YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQLG-HDLPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEET

RKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVG--DSL-LETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALP
|.||||||||. . ||    ||||||||||.||. .... |||. .   |  |   |.| |||| || ||.|.| .| |  ||.|| |..|..|..|.||
RHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFLP

FDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWY
|||||.. .  |. .|... |... |  . ||| |. |.|.||.|. .. .||| 
FDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase BRSK1.AA Pkinase_Tyr 50-194 30 6.7e-20 68.03 Pfam 1-158 (270) Show / Hide 
Range on Protein: 50-194
Range on HMM: 1-158/270
Sequence Identity: 30% (49 aa)

YRLEKTLGKGQTGLVKLGVHC----ITGQKVAIKIVNREKLSESV--LMKVEREIAILKLI-EHPHVLKLHDVYE-NKKY--LYLVLEHVSGGELFDYLV
 .. |.||.|. | |..|.       |...||.|.. .|. ...   . .  ||..|.| .  ||....|. |    ..   .|.|.|.. .| | ||| 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

K----KGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMA
|    |..||.|.  .. .|| ..... .|  . ||||   | |..|.| ..|.|||.|
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase BRSK1.AA TyrKc 50-302 23 3.3e-16 39.28 SMART 1-280 (280) Show / Hide 
Range on Protein: 50-302
Range on HMM: 1-280/280
Sequence Identity: 23% (68 aa)

YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLI--EHPHVLKLHDVYENK-------KYLYLVLEHVSGGELFDYLVK
 .|.|.|| |. | | .|.     ..||.| .. ..     ..   ||. |.. .  .||....|. |   .       . |..|.|....| | ||| |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KGR-LTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-------SLLETSC--GSP-----HYACPEVIKGEKYDG
... |..|.  .|  || .  .. ||  . ||||   | |..|.. ..|.|||..     |       .   ..   |.          ||.|.  |.  
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-

RRADMWSCGVILFALL-VGALPFDD-----DNLRQLLEKVKRG-VFHMPHF--------IPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWYL
   | || || .. ..  |. |  .      . ....|.||.|     |.          |..  .. .   . .||.| . ..|     ..
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI---HECF
Kinase BRSK1.AA GIN4 50-86 40 2.5e-09 25.5 In-house 1-37 (293) Show / Hide 
Range on Protein: 50-86
Range on HMM: 1-37/293
Sequence Identity: 40% (15 aa)

YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKL
..| .|||.| || |.|  .  |||. |.|.. . |.
WKLGETLGFGSTGKVQLAKNMETGQRAAVKVISKKKI
UBA_CAMKL BRSK1.AA UBA_CAMKL 332-371 31 1.8e-13 46.47 In-house 1-41 (41) Show / Hide 
Range on Protein: 332-371
Range on HMM: 1-41/41
Sequence Identity: 31% (13 aa)

DPDVLESMASLGCFRDRERLHRELRSEEE-NQEKMIYYLLL
|..... |...... ||| ... ||.    |.....|||||
DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL