Gene caMLCK (Human)

caMLCK

Species: Human
Alias: MGC126319, MLCK, caMLCK, MLCK2, MGC126320
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 16q13.1,

Classification

Group: CAMK
Family: MLCK

Sequence

Name Sequence Type Origin Length Description Download
caMLCK.AA Protein Sugen Kinome 819 None Fasta, JSON
caMLCK.kin_dom Protein Kinase Domain Sugen Kinome 256 None Fasta, JSON
caMLCK.NA RNA Sugen Kinome 7998 None Fasta, JSON

Protein domain

Protein domains of caMLCK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase caMLCK.AA MLCK 515-770 64 1.8e-242 647.25 In-house 1-257 (257) Show / Hide 
Range on Protein: 515-770
Range on HMM: 1-257/257
Sequence Identity: 64% (167 aa)

VCQHEVLGGGRFGQVHRCTEKSTGLPLAAKIIKVKSAKDREDVKNEINIMNQLSHVNLIQLYDAFESKHSCTLVMEYVDGGELFDRITDEKYHLTELDVV
.  ||.||.|.||.||||.|||||. .|||.||....||.|.|||||.||||| | ||||..||||.|......|||..|||||.||.||..||||..|.
YQIHEELGRGKFGIVHRCIEKSTGKTWAAKFIKCRKPKDKENVKNEIEIMNQLHHPNLIQCHDAFETKNEMVMIMEYISGGELFERIVDEDFHLTEREVI

LFTRQICEGVHYLHQHYILHLDLKPENILCVNQTGHQIKIIDFGLARRYKPREK-LKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSPFL
...||||||||..|...|.|||||||||.|...|.||||||||||||.|.|.|| .||.||||||.|||||||..|.|.|||||||||.||||||||||.
HYMRQICEGVHHMHWQNIVHLDLKPENIMCQTRTSHQIKIIDFGLARKYDPDEKKVKVMFGTPEFVAPEVVNYDPVGFQTDMWSVGVICYMLLSGLSPFM

GETDAETMNFIVNCSWDFDADTFEGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWL
|..|.||||.. .| |||| ..|.. |.|||||.||||||.|..||.|..||.|.||
GDNDRETMNNVTSCEWDFDDECFDDISDEAKDFISRLLVKDKEKRMTAHECLQHPWL
Kinase caMLCK.AA DAPK 517-770 46 1.4e-129 359.12 In-house 1-264 (264) Show / Hide 
Range on Protein: 517-770
Range on HMM: 1-264/264
Sequence Identity: 46% (124 aa)

QHEVLGGGRFGQVHRCTEKSTGLPLAAKIIKV-KSAKD-----REDVKNEINIMNQLS-HVNLIQLYDAFESKHSCTLVMEYVDGGELFDRITD-EKYHL
. | || |.|  | .|..||||.  ||| ||  .....     ||. . ||.|  ... | |.| | ...| .    |. ||| |||||| .    . .|
MGEELGRGQFAVVRKCRHKSTGKHYAAKFIKKRRRGQSRRGVCREEIEHEIAILEECRGHPNVINLHEVYETRTDVILILEYVSGGELFDYCCEDREECL

TELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQTGHQ--IKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLL
.| |.. | .|| |||||||.  | ||||||.||.  .    |  ||||||||.|. .. | ..  .||||..|||.||||  |  |||||.|||||..|
CEEDATRFMKQILEGVHYLHSRNICHLDLKPQNIMLTDRNIPQGDIKIIDFGLSRKICNGEEFRDIMGTPEYVAPEIVNYEPLSLATDMWSIGVITYIML

SGLSPFLGETDAETMNFIVNCSWDFDADTFEGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWL
|| |||||.|  ||   |  .. ||.  .|...||.||||  |||||.   ||.|..||.| |.
SGISPFLGDTKQETFLNISQVNYDFSEEYFSCTSEHAKDFIRRLLVKDPEKRMTAEECLQHPWI
Kinase caMLCK.AA CAMK 520-770 26 1.6e-121 393.59 In-house 1-425 (425) Show / Hide 
Range on Protein: 520-770
Range on HMM: 1-425/425
Sequence Identity: 26% (113 aa)

VLGGGRFGQVHRCTEKSTG------------LPLAAKIIKVK----------------------------SAKDREDVKNEINIMNQLS-------HVNL
.|| |.||.|..|..|.|.               |.|||. |                            ..|||. |..||.||..|.       | |.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IQLYDAFESKHS-------------------CTLVM---EYVDGGEL----FDRITDEKY--------------HLTELDVVLFTRQICEGVHYLHQHYI
|.||...|..|                    . .||   ||..||||    ||.|.. ..              ..|| ..  . ||||..|||.|.| |
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

LHLDLKPENILCVNQTG---------------HQIKIIDFGLARRYKP------------------------REKLKVNFGTPEFLA-PEVVNY------
 |.||||||||...  .               ..|||||||.|....|                         .|.|  .||||. | |||.|.      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------EFVSFPTDMWSVGVITYMLLSGLSPFLGE-------------TDAETMNFIVNCSWDFDADTFEG--------------------LSEEAKD
        . .....||||.|||.|..|.| .|| |.             .| |..  | .. .||. . | .                    .|.|.||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

FVSRLLVKEKSCRMSATQCLKHEWL
.....|... . ||...|||.|.|.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase caMLCK.AA Trio 513-770 38 6.4e-113 290.78 In-house 1-258 (258) Show / Hide 
Range on Protein: 513-770
Range on HMM: 1-258/258
Sequence Identity: 38% (100 aa)

YEVCQHEVLGGGRFGQVHRCTEKSTGLPLAAKIIKVKSAKDREDVKNEINIMNQLSHVNLIQLYDAFESKHSCTLVMEYVDGGELFDRITDEKYHLTELD
|..  .| .| |||. |.||..|.||. .|||.|  . ..|.| |  |  ..  |.|  ...| |..|.  .  |. |  |.||| ...  ..  ..| .
YTF--QEEIGRGRFSVVRRCWHKATGRTCAAKFIPYR-MMDKEQVYHEYEMLQHLQHPCVCSLHDTYETPRHYILILELCDDGELLCCLM-RWGSYCESE

VVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQTG--HQIKIIDFGLARRYKPR--EKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSG
|  . .|. |.|||||.. |||||.||||.. .   .   ||||.||| |  . |   | .    |.||| |||... . ||  || ||.||.|| .|||
VKTYMWQMLEAVHYLHNCHILHLDIKPENMMMWHYNAGRPQIKICDFGDAQQLWPHKVEPQHHQYGNPEFMAPEIIQGNPVSYGTDIWSIGVLTYVMLSG

LSPFLGETDAETMNFIVNCSWDFDADTFEGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWL
 |||..| | ||   |..   .|  ..| ..|..||.|.  .|.   . | .| .|| | |.
ISPFYDESDRETCMNICRGDFSFPECYFCHVSQNAKHFICKVLQEDPWKRPCASECLQHPWF
Kinase caMLCK.AA DAPK 517-770 47 1.2e-112 326.2 In-house 3-264 (264) Show / Hide 
Range on Protein: 517-770
Range on HMM: 3-264/264
Sequence Identity: 47% (125 aa)

QHEVLGGGRFGQVHRCTEKSTGLPLAAKIIKVKSAK------DREDVKNEINIMNQLS-HVNLIQLYDAFESKHSCTLVMEYVDGGELFDRITDEKYHLT
. | .| | |  | .|.|||||.  ||| ||    .       |||.  |..|  ... | | | | |..| |    |. | | |||||| .  || .|.
MGEEIGSGQFAVVKKCREKSTGKEYAAKFIKKRRYTASRRGVSREDIEREVSILREIRGHPNIITLHDVYENKTDVVLILELVSGGELFDFLC-EKECLN

ELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQTGHQ--IKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLS
|     |  || .|||..|   | |.|||||||   .    .  |||||||||.| .| .  |  |||||| |||.||||  .  |||||.||||| |||
EEEATQFIKQILDGVHHMHSKHICHFDLKPENIMLLDRNVPNPRIKIIDFGLAHRIEPGNEFKNIFGTPEFVAPEIVNYEPLGLETDMWSIGVITYILLS

GLSPFLGETDAETMNFIVNCSWDFDADTFEGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWL
| |||||.|  ||.  |   . .||   |   || ||||. |||||.   ||   .||.| | 
GASPFLGDTKQETLANITAVNYHFDEEYFKNTSEHAKDFIRRLLVKDPKKRMTIQECLQHPWI
Kinase caMLCK.AA CAMK1 513-770 37 2.4e-107 313.13 In-house 1-276 (276) Show / Hide 
Range on Protein: 513-770
Range on HMM: 1-276/276
Sequence Identity: 37% (106 aa)

YEVCQHEVLGGGRFGQVHRCTEKST---GLPLAAKIIK-VK-SAKDR----EDVKNEINIMN---QLSHVNLIQLYDAFESKHSCTLVMEYVDGGELFDR
||.  ....| | |..|..||.|.|   | . | |.|.  |  .|..    | ..|||.||    ...| | |..|. .||.    ||||.| |||||||
YEF--GKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDR

ITDEKYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQ-TGHQIK--IIDFGLARRYKPRE-KLKVNFGTPEFLAPEVVNY---EFVSFPT
| . . . || | ..  .||.. |.|.|.. | | ||||||.|....  ...||  |.||||...... | ..|  .|||.. ||||...   .. . . 
IVEKG-NYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKAC

DMWSVGVITYMLLSGLSPFLGET-DAETMNFIVNCSWDFDADTFEGLSEE-AKDFVSRLLVKEKSCRMSATQCLKHEWL
||||.||||| || | .|| .|. |.| .  | .|...|. . .   |.. ||||.. .|... . | ...|||.| |.
DMWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase caMLCK.AA S_TKc 515-770 34 8.9e-94 318.76 SMART 1-231 (231) Show / Hide 
Range on Protein: 515-770
Range on HMM: 1-231/231
Sequence Identity: 34% (93 aa)

VCQHEVLGGGRFGQVHRCTEKSTGLPLAAKIIKVKSAKDREDVKNEINIMNQLSHVNLIQLYDAFESKHSCTLVMEYVDG--GELFDRITDEKYH-----
   ....| | ||.|..|..|.||   | ||||       |....||.|. .  | |...|||.|.. ..  .||||.||  |.|||.| . ..|     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQTGHQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYEFVSF-PTDMWSVGVITYMLL
..| ..  ...|||... |.|.| |.| ||||||||. .    .|||.||||||..      .   |||...||||.     .. . |.||.|.| | .|
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

SGLSPFLGETDAETMNFIVNCSWDFDADTFEGLSEEAKDFVSRLLVKEKSCRMSATQCLK-------HEWL
.|  ||   ....... |.              |.|||||....|.|. . |..| ..|.       |.|.
CGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase caMLCK.AA DRAK 517-770 39 2.1e-92 287.45 In-house 1-259 (259) Show / Hide 
Range on Protein: 517-770
Range on HMM: 1-259/259
Sequence Identity: 39% (103 aa)

QHEVLGGGRFGQVHRCTEKSTGLPLAAKIIKV-KSAKD-REDVKNEINI-MNQLSHVNLIQLYDAFESKHSCTLVMEYVDGGELFD-RITDEKYHLTELD
    .| |.|  | .| .|.||   ||| .|  . ..| |.... || . |.  .  ..| | . .| .    ||.||  |||.|.  . |.   ..| |
TAKERGRGKFAVVRKCIHKNTGQHFAAKFMKKRRRGQDCRMEILHEIAVLMLCQDCPWVINLHEVYETRSEMILVLEYAAGGEIFQYCVADKEECFCEKD

VVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQTGHQ-IKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSP
|.   ||| ||||||||  | |||||| |||    .    |||.|||..|  .  | .    |||...|||. ||. ..  |||||.||.||..|...||
VQRCMRQILEGVHYLHQRNIVHLDLKPQNILLTSEYPEDDIKICDFGMSRYICNGEEVREIMGTPDYVAPEILNYDPITMATDMWSIGVLTYVMLTHISP

FLGETDAETMNFIVNCSWDFDADTFEGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWL
|.|..  ||   |  |  |.  ..|...|..| ||. .|.|..   ||.|..||.| ||
FVGDDKQETFLNISQCNLDYSEEMFSCHSPVAIDFIQSLCVIKPEDRMTAEECLDHPWL
Kinase caMLCK.AA Ciliate-E2a 513-770 38 5.6e-85 250.07 In-house 1-275 (275) Show / Hide 
Range on Protein: 513-770
Range on HMM: 1-275/275
Sequence Identity: 38% (108 aa)

YEVCQHEVLGGGRFGQVHRCTEKSTGLPLAAKIIKVKSAKDR---EDVKNEINIMNQLSHVNLIQLYDAFESKHSCTLVMEYVDGGELFDRITDEKYHLT
|..  . ..| | ||.|   . | ||   |.|... | . .    | ..|||||| ||.| |.|.||. .|....  |||||..||||.|.|   |   .
YKF--IKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFE

E-LDVVLFTRQIC-EGVHYLHQHYILHLDLKPENILCV--NQTG---HQIKIIDFGLARRYKPREK--LKVNFGTPEFLAPEVVNYEFV------SFPTD
|  ..  . .|.  .|.||.||  |.| ||||||||    ....    .|||||||||..... ||  ...  ||| ..|||| |.. |      .   |
EIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCD

MWSVGVITYMLLSGLSPFLGETDAETMNFIVNCSWDFDADT-FEGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWL
|||.||| | ||.| .|| |.| .|.   . .|  ||.    .| .| |.||.....|.|  . | .|.|.|.| | 
MWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase caMLCK.AA Pkinase 515-770 34 2.1e-84 291.54 Pfam 1-293 (293) Show / Hide 
Range on Protein: 515-770
Range on HMM: 1-293/293
Sequence Identity: 34% (101 aa)

VCQHEVLGGGRFGQVHRCTEKSTGLPLAAKIIKVKSAKDREDVKN----EINIMNQLSHVNLIQLYDAFESKHSCTLVMEYVDGG----ELFDRIT-DEK
 . ....| | ||.| .|..|.||   | ||||....|. .|. .    || ||. |.| | ..|||.||.| .. .||||..||    .|||.|. ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

YHL--TELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQTGHQ---IKIIDFGLARR--YKPREKLKVNFGTPEFLAPEVVN-YEFVSFPTDMWS
  .  .| ..  . .||..|. |.|.. |.| ||||||||.. ..||    .||.|||||.   | . . ...  |||...||||.. ..  . . ||||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

VGVITYMLLSGLSPFLGE------TDAETMNFIVNCSWDFDADTFEGLS-----------------EEAKDFVSRLLVKEKSCRMSATQCLKHEWL
.|.| | .|.|  || |.      .. . .. |  . ..|| ..    |                 ||.|||....| |  ..| .|.|.|.|.|.
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase caMLCK.AA CAMKL 513-770 30 1.8e-76 243.55 In-house 1-297 (297) Show / Hide 
Range on Protein: 513-770
Range on HMM: 1-297/297
Sequence Identity: 30% (92 aa)

YEVCQHEVLGGGRFGQVHRCTE-KSTGLPLAAKIIKVKSAKDREDVKN---------------EINIMNQLS---HVNLIQLYDAFESKHS------CTL
|....  .|| | ||.|  .|  . ||   | |||. | ..... .|.               ||.|| .|.   | | |.||. .| .        . |
YRIGK--TLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYL

VMEYVDGGE--LFDRITDEKY---HLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQTGHQIKIIDFGLARRYKP-----REKLKVNFGTPE
||||..|||  |||.|  ...    ..| .   . |||...|.|.|.| | | |.||||||  ..  ..|||||||..  |.|      .|||   |.|.
VMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPP

FLAPEVVNY--E-FVSFPTDMWSVGVITYMLLSGLSPFLGET-------DAETMNFIVNCSWDFDADTFEGLSEEAKDFVSRLLVKEKSCRMSATQCLKH
. |||...   . .  ...|.|| ||| |... |  || ..|       .  ..  ...|   .  . .  .| ...|. ...|..  . |... | ..|
YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG--YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNH

EWL
.|.
PWM
Kinase caMLCK.AA Ciliate-E2 513-770 24 6.8e-75 255.12 In-house 1-365 (365) Show / Hide 
Range on Protein: 513-770
Range on HMM: 1-365/365
Sequence Identity: 24% (93 aa)

YEVCQHEVLGGGRFGQVHRCTEKSTG-LP-----------------LAAKIIKVKSA--KDREDVKNEINIMN----------------QLSHVNLIQLY
|..  ....| | ||.| .|. .... .                   ..||. .|.   .. | .|.||.||.                ||.| |.|..|
YKF--IKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMY

DAFE--SKHSCTLVMEYVDGGELFDRIT--DEKY--------HLTELDVVLFTRQICE---------------GVHYLHQHY-ILHLDLKPENILCVNQT
..|.  ..... |||||..||.|||.|   . |          .||  .  ...||..               ...|||.   |.| |.||||||     
ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

GHQIKIIDFGLARRYKPR----------EKLKVNF-----------------------GTPEFLAPEVVNYEF---------VSFPTDMWSVGVITYMLL
   ||||||||...|..           ....  .                       |||...|||..|..           ..  |.||.||| |..|
---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEML

SGLSPFLGETDAETMNFIVNCSWDFDAD--------------TFEGLSEEAKDFVSR----LLVKEKSCRMS-ATQCLKHEWL
.|  ||        .. | .| .||.                 .. .|.|.||. ..    .|.|. . |.. . |.|.|.|.
FGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase caMLCK.AA Pkinase_Tyr 515-661 33 9.1e-22 74.35 Pfam 1-159 (270) Show / Hide 
Range on Protein: 515-661
Range on HMM: 1-159/270
Sequence Identity: 33% (54 aa)

VCQHEVLGGGRFGQVHRCTEK----STGLPLAAKIIKVKSAKD---REDVKNEINIMNQL-SHVNLIQLYDAFE-SKHS--CTLVMEYVDGGELFDRITD
.   ..|| | ||.|...| |    .|..| | |..| .. ..   |||  .|..|| || .| |...|| .    . .    .||||. .| | |   .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

E---KYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQTGHQIKIIDFGLAR
    | .||  | . . .||..|  ||... . | ||   |.|  .  ....|| ||||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE--NNVVKICDFGLAR
Kinase caMLCK.AA TyrKc 515-770 24 2.1e-15 26.47 SMART 1-280 (280) Show / Hide 
Range on Protein: 515-770
Range on HMM: 1-280/280
Sequence Identity: 24% (70 aa)

VCQHEVLGGGRFGQVHRCTEKSTGLPLAAKIIKVKSAKDREDVKNEINIMNQL--SHVNLIQLYDAFESK-------HSCTLVMEYVDGGELFDRITDEK
.   ..|| | ||.|...| |   .. | | .|  .   |||  .|..|| .|  .| |...|| .  ..       .   .||||...| | |.. . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

YHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQTGHQIKIIDFGLARRYKPR-------EKLKVNF--GTPE-----FLAPEVVNYEFVSF
 .|.  | . |  ||..|  |||.. . | ||   |.|  ..   ..|| ||||.|  .         .  ..    |.        .|||. ||   ..
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

PTDMWSVGVITY-MLLSGLSPFLG-----ETDAETMNFIVNCSWDFDADT-----FEGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWL
 .| || ||  . ..  | .|  |      ...| .... .       .      | . ..|  .  ..    . ..| . ...  || .
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF