Gene CK1a2 (Human)

CK1a2

Species: Human
Alias: CSNK1A1L, CK1a2, MGC33182, RP11-532O21.2
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 13q12.3,

Classification

Group: CK1
Family: CK1
Subfamily: CK1-A

Sequence

Name Sequence Type Origin Length Description Download
CK1a2.NA RNA Sugen Kinome 2405 None Fasta, JSON
CK1a2.AA Protein Sugen Kinome 337 None Fasta, JSON
CK1a2.kin_dom Protein Kinase Domain Sugen Kinome 261 None Fasta, JSON

Protein domain

Protein domains of CK1a2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CK1a2.AA CK1 17-275 73 1.8e-211 708.79 In-house 1-271 (271) Show / Hide 
Range on Protein: 17-275
Range on HMM: 1-271/271
Sequence Identity: 73% (200 aa)

YKLVRKIGSGSFGDVYLGITTTNGED--VAVKLESQKVKHPQLLYESKLYTILQG------GVGIPHMHWYGQE--KDNNVLVMDLLGPSLEDLFNFCSR
|...||||.|||||.|||| .||||   ||.|||..| |||||.||.|.|.||||      ..|||||.|.|||  .| |..||||||||||||||||.|
YRVGRKIGQGSFGDIYLGINMTNGEENHVAIKLEKNKSKHPQLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDLFNFCNR

RFTMKTVLMLADQMISRIEYVHTKNFLHRDIKPDNFLMGT-GRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKHLIGTVRYASINAHLGIEQSRRDDME
.|..|||||.|||||.||||||.|||.||||||||||||. |.||.....|||||||.||| .|.|||||||.| |.||.||||||.|||||||||||||
KFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDME

SLGYVFMYFNRTSLPWQGLRAMTKKQKYEKISEKKMSTPVEVLCKG-FPAEFAMYLNYCRGLRFEEVPDYM
|||||.|||.| |||||||.| |||||||||.|||||||||.|||| ||.||||||||||.|.||| ||||
SLGYVLMYFLRGSLPWQGLKANTKKQKYEKIMEKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM
Kinase CK1a2.AA CK1-A 17-277 84 1.1e-205 689.54 In-house 1-261 (261) Show / Hide 
Range on Protein: 17-277
Range on HMM: 1-261/261
Sequence Identity: 84% (221 aa)

YKLVRKIGSGSFGDVYLGITTTNGEDVAVKLESQKVKHPQLLYESKLYTILQGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLML
|.||||||||||||.||||..||||.||.|.||.|..||||.||.|.|.||||.||||||.|||.|||.||.||||||||||||||||.|||||||||||
YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARHPQLIYEAKVYRILQGCVGIPHMRWYGCEKDYNVMVMDLLGPSLEDLFNFCKRRFTMKTVLML

ADQMISRIEYVHTKNFLHRDIKPDNFLMGTGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKHLIGTVRYASINAHLGIEQSRRDDMESLGYVFMYFNR
|||||.||||||.|||.||||||||||||.||||||||||||||||||||.||||||||||||.|.||.|||||||||||||||||||||.|||.|||||
ADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYVMMYFNR

TSLPWQGLRAMTKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYL
..|||||..|||||||||||||||||||.|.|||||||||.||.||||.|||||.||||||
GKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL
Kinase CK1a2.AA CK1-Unclassified 17-249 62 1.6e-193 576.47 In-house 1-244 (244) Show / Hide 
Range on Protein: 17-249
Range on HMM: 1-244/244
Sequence Identity: 62% (153 aa)

YKLVRKIGSGSFGDVYLGITTTNGEDVAVKLESQKVKHPQLLYESKLYTILQGGV-------GIPHMHWYGQE--KDNNVLVMDLLGPSLEDLFNFCSRR
|....|||.||||..|..| . ..| ||.|||. ..|||||.|| |....||.|        |||.|.|.|||   | |..||||||||||||||.| |.
YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSKHPQLCYEAKIMQYLQNGHNCDNFIKGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDLFNMCNRK

FTMKTVLMLADQMISRIEYVHTKNFLHRDIKPDNFLMG-TGRHCNKLFLIDFGLAKKYRDN-RTRQHIPYREDKHLIGTVRYASINAHLGIEQSRRDDME
|..|||||.|||||.||||.| |||.|||||||||||| .|.. .....|||||.|.|.|  .| .||||||.| |.|| ||||||||||||||||||.|
FSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLGIEQSRRDDLE

SLGYVFMYFNRTSLPWQGLRAMTKKQKYEKISEKKMSTPVEVLC
|||||..|| . |||||...| .||.||||| |.||||||| ||
SLGYVLIYFLKGSLPWQNIKANNKKEKYEKIMEMKMSTPVEQLC
Kinase CK1a2.AA CK1-D 17-277 69 2.4e-175 588.84 In-house 1-261 (261) Show / Hide 
Range on Protein: 17-277
Range on HMM: 1-261/261
Sequence Identity: 69% (181 aa)

YKLVRKIGSGSFGDVYLGITTTNGEDVAVKLESQKVKHPQLLYESKLYTILQGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLML
|.. ||||||||||.|.| . ...|.||.|||. | ||||| .|||.| ..|||.|||...|.||| | ||.||||||||||||||.|.|.| .||||||
YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTKHPQLHIESKFYKMMQGGIGIPEIRWCGQEGDYNVMVMDLLGPSLEDLFNYCHRKFSLKTVLML

ADQMISRIEYVHTKNFLHRDIKPDNFLMGTGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKHLIGTVRYASINAHLGIEQSRRDDMESLGYVFMYFNR
|||||.||||.|..||.|||||||||||| |.. |  ..|||||||.||| ||.|||||||.| | || |||||| |.|||||||||.||||||.|||||
ADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYVLMYFNR

TSLPWQGLRAMTKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYL
 |||||||.|.||.||||.|.||||||....||||.| ||. |.|||| |.|.. |||.||
GSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL
Kinase CK1a2.AA CK1-G 17-277 54 4.1e-142 478.41 In-house 1-266 (266) Show / Hide 
Range on Protein: 17-277
Range on HMM: 1-266/266
Sequence Identity: 54% (144 aa)

YKLVRKIGSGSFGDVYLGITTTNGEDVAVKLESQKVKHPQLLYESKLYTILQGGV-GIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLM
|.  .||| |.|| ...|    |.| ||.|.|  | . |||  | . | || | . |||. ...||.   |..|||||||||||||..| |.|..|||.|
YRVGKKIGCGNFGELFEGKNMYNNEHVAIKFEPMKSRAPQLHDEYRFYKILNGCPEGIPQVYYFGQCGKYNIMVMDLLGPSLEDLFDWCDRKFSVKTVCM

LADQMISRIEYVHTKNFLHRDIKPDNFLMG--TGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKHLIGTVRYASINAHLGIEQSRRDDMESLGYVFMY
.| |||.|.||||... . ||.|||||| |    .. .....||||.||.|.| .|.||||||| | | || || ||| ||| |||||||||.|| .|||
VAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYIDPETKQHIPYREHKSLTGTARYMSINTHLGREQSRRDDMEALGHMFMY

FNRTSLPWQGLRAMTKKQKYEKISEKKMSTPVEVLCKG--FPAEFAMYLNYCRGLRFEEVPDYMYL
| | |||||||.| . |..|.|| ..| .|..|.||..  || .|| || | | | |.| ||| ||
FLRGSLPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL
Kinase CK1a2.AA CK1 17-277 38 1.4e-140 473.36 In-house 1-339 (339) Show / Hide 
Range on Protein: 17-277
Range on HMM: 1-339/339
Sequence Identity: 38% (132 aa)

YKLVRKIGSGSFG-DVYLG-----ITTTNG-----EDVAVKLESQKVK--HPQLLYESKLYTILQGG-------------------VGIPHMHWYGQEKD
.|.|.|||.|.|| ..|..     . ..|.     |..|.|.|. | .  ||||..|...| .||||                   ...|.|.||..|.|
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED

--NNVLVMDLLGPSLEDLFN---FCSRRFTMKTVLMLADQMISRIEYVHTKNFLHRDIKPDNFLMGT------GRHCN--------KLFLIDFGLAK-KY
  .|..||.||||.||||..   .| |.|.|||.||.|.||....||.| ..|.|||||||||.||       |.| .        ....||||.|. ||
DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKH-HHEWNNEHRQVYMIDFGMARRKY

RDN-----------RTRQHIPYRE---DKHLIG-TVRYASINAHLGIEQSRRDDMESLGYVFMYFNRTS--LPWQGLRAMTK-------KQKYEKISEKK
||.           .| ||.|.||    | ..| |.||.|||.|||.||.||||..|..|....... .  ||||.... .|       |.|||.|.|||
RDKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKK

MSTPVEVLCKG-----FPAEFAMYLNYCRGLRFEEVPDYMYL
||||.. ||..     .| || ....|.|.|.... |||...
MSTPFF-LCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase CK1a2.AA Worm6 17-277 26 1.3e-55 191.05 In-house 1-279 (279) Show / Hide 
Range on Protein: 17-277
Range on HMM: 1-279/279
Sequence Identity: 26% (75 aa)

YKLVRKIGSGSFGDVYLGITTTNGE--DVAVKLES--QKVKHPQLLYESKLYTIL--QGGVGIPHMHWYGQEKD--NNVLVMDLLGPSLEDLFNFC-SRR
.|...|||.|.||.||.   .....   .|.|.|.   . |...|  |    . .  ... . . .  .|. .    | .|| |.|..|.||  ..  |.
WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDRK

FTMKTVLMLADQMISRIEYVHTKNFLHRDIKPDNFLMGT-----GRHCNKLFLIDFGLAK-KYRDNRTRQHIPYR-EDKHLIGTVRYASINAHLGIEQSR
|.| | | .| |.. .|| .|   |.|||.|| ||  |       .   .....|||... |. .|.  . .. | .. .  ||||||....| |.||.|
FSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRWTACGFRGTVRYAPLACHKGQEQCR

RDDMESLGYVFMYFNRTSLPWQGLRAMTKKQ-KYEKISEKKMSTPVEVLCKGFPA-EFAMYLNYCRGLRFEEVPDYMYL
.||.||  |.   . .  |||......  ..  ....  .. ..  . . ...|. ||   . |  ...... ||| ..
KDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI
Kinase CK1a2.AA TTBKL 17-281 28 9.3e-52 173.04 In-house 1-288 (288) Show / Hide 
Range on Protein: 17-281
Range on HMM: 1-288/288
Sequence Identity: 28% (84 aa)

YKLVRKIGSGSFGDVYLGITTTN-GEDVAVKLESQKVKHPQ--LLYESKLYTILQ--GGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLF--NFCSRRFT
.. |..||.| || ||... ... ..  |.| |...  .    .  | .. . ||  |   .|..|..|..|| | .|| |.||.| ||   . . .||.
WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFS

MKTVLMLADQMISRIEYVHTKNFLHRDIKPDNFLMGTGRH----CNKLFLIDFGLAKKYRDNRTRQ----------HIPYRE---DKHLIGTVRYASINA
  |.. .. | .  . ..| . |.|||.|| |. .|   |    |  ..|||||.|..|...   .          . . |.      . ||.||.|.|.
DGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNM

HLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLRAMTKKQKYEKISEKKMSTPVEVLCKG------FPAEFAMYLNYCRGLRFEEVPDYMYLRQLF
|.. ||.| ||. |. |......   |||...       . ..| ..|...  |.|.|.      .| ||..   . | ||. . |||......|
HDRKEQGRHDDLWSWMYMIIELHCG-LPWTNM------EDKMEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF
Kinase CK1a2.AA TTBK 17-277 37 2.8e-46 160.09 In-house 1-257 (257) Show / Hide 
Range on Protein: 17-277
Range on HMM: 1-257/257
Sequence Identity: 37% (99 aa)

YKLVRKIGSGSFGDVYLGITTTNG-EDVAVKLESQKVKHPQLLYESKLYTILQGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSR-RFTMKTVL
 | |.||| | || .| .    |  | ||.|.|| . .   |  |      |||   .      | . . | .||.|.| .| ||    .|  |.. | |
WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVESAQQPKQVLKMEVAVLKKLQGCDHVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFSLSTTL

MLADQMISRIEYVHTKNFLHRDIKPDNFLMG-TGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKHLIGTVRYASINAHLGIEQSRRDDMESLGYVFMY
 |  |..  || .|   |||||||| || || .   |.| ...||||| .|  | . .  | ||     |||||||||||.  |  |.||. || |.   
RLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYT-NACGEVRPPREVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVE

FNRTSLPWQGLRAMTKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYL
|    |||  .     | | ... | |      .| |  | || ....  . | .|. |||  .
FVQGQLPWRKI-----KDK-DQVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI
Kinase CK1a2.AA Pkinase 17-236 23 6.1e-35 124.62 Pfam 1-230 (293) Show / Hide 
Range on Protein: 17-236
Range on HMM: 1-230/293
Sequence Identity: 23% (56 aa)

YKLVRKIGSGSFGDVYLGITTTNGEDVAVKLESQKVKHPQLLY------ESKLYTILQGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFC------
|...||||||||| ||...   .|. ||||  . . .... ..      | ..   |.    .   .|.   ||.  .||....  |. ..  .      
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLY-VMDLFDYISTW

-SRRF--TMKTVLMLADQMISRIEYVHTKNFLHRDIKPDNFLMG-TGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKHLIGTVRYASINAHL-GIEQS
 ...|  ..... . . |... .|| | ....|||.||.|.|.  .|  . .. ..||||||...      . ...  ... || .|..   .. | . .
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYG

RRDDMESLGYVFMYFNRTSLPWQGL----RAMTKKQKYEKI
.. || |.| .. ..    .|..|     . ....|....|
PKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRI
Kinase CK1a2.AA VRK 88-221 38 3.8e-26 81.09 In-house 106-240 (284) Show / Hide 
Range on Protein: 88-221
Range on HMM: 106-240/284
Sequence Identity: 38% (53 aa)

LVMDLLGPSLEDLFN-FCSRRFTMKTVLMLADQMISRIEYVHTKNFLHRDIKPDNFLMGTGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKHLI--GT
.||. .| .|. .    .  ||.||||| || .|.   || | ..  | |||  | | |     .. .|.|.||| .| .|    | .| ||.     ||
MVMPRFGRDLQKIYEDQNGHRFSMKTVLQLACRMLDVLEYLHENEYVHGDIKAANILLGFEKNPDQVYLVDYGLAYRYCPN--GKHRQYKEDPRRCHNGT

VRYASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPW
  . |. ||.|   ||| | |.|||  |.    .|||
CEFTSMDAHKGCAPSRRSDLEILGYCMMMWLYGYLPW
Kinase CK1a2.AA S_TKc 17-299 17 3.8e-14 30.48 SMART 1-231 (231) Show / Hide 
Range on Protein: 17-299
Range on HMM: 1-231/231
Sequence Identity: 17% (53 aa)

YKLVRKIGSGSFGDVYLGITTTNGEDVAVKLESQKVKHPQLLYESKLYTILQGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRR--------F
|...||||.|.|| ||... .  |. ||.|  .      ... | ..     .   | ... . |. |.  .||.... .| ||| .  .|        |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

TMKTVLMLADQMISRIEYVHTKNFLHRDIKPDNFLMGTGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKHLIGTVRYASINAHLGIEQSR-RDDMESL
.  ..  .. |... .|| | ....|||.||.| |. .      . ..|||||...              ....||  | .         .. . |. |.
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL--------------TTFCGTPWYMAPEVL---GYGKCKCDWWSC

GYVFMYFNRTSLPWQGLRAMTKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYD-------YT-----
| ..  .     |..     . .. ..||                                         ...  .. . |.   .        .     
GCILYEMLCGYPPFP-----QMQMMFKKIG---------------------------------------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDI

--FDWT
    | 
KCHPWF
Kinase CK1a2.AA Pkinase_Tyr 17-46 35 3.1e-07 25.14 Pfam 1-34 (270) Show / Hide 
Range on Protein: 17-46
Range on HMM: 1-34/270
Sequence Identity: 35% (12 aa)

YKLVRKIGSGSFGDVYLGITT----TNGEDVAVK
 .. .|.|.|.||.||.|. .     .. .||||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVK
Kinase CK1a2.AA TyrKc 17-275 18 2e-06 -118.38 SMART 1-280 (280) Show / Hide 
Range on Protein: 17-275
Range on HMM: 1-280/280
Sequence Identity: 18% (57 aa)

YKLVRKIGSGSFGDVYLGITTTNGEDVAVKLESQKVKHPQLLYESKLYTIL---------QGGVGIPH----MHWYGQEKDNNVLVMDLLGP-SLEDLFN
 .| .|.|.| || ||.|. .   ..||||       .  .. | .. . |           || . .    |     . .   .|| .    .| |   
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFM-----YIEPLMIVMEYMPHGDLKDYLR

FCSRRFTMKTVLMLADQMISRIEYVHTKNFLHRDIKPDNFLMGTGRHCNKLFLI---DFGLAKKYRDN---RTRQHIPYREDK--HLI--GTVRYASINA
 . ....||. |  . |  .  || | ||. |||.   | | | ..       .   ||||...  |        .  ||  .  .      .|  ..  
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH------TVKISDFGLSRDIYDDDQQG-ESKDYYRKKEHKGGKTMLPIRWMAP--

HLGIEQSRRDDMESL-GY-------VFMY-------FNRTSLPWQGLRA--MTKKQKYEKISEKKMSTPVEVLCKG-----FPAEFAMYLNYC------R
            |..  .       |...       | .   |. |     |. .. .|.. . ..  . .  .        |.|  .    |       
------------ECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQIMKQCWHEDPED

GLRFEEVPDYM
  .|.|. ...
RPTFSEIHECF
Kinase CK1a2.AA VRK 17-41 36 0.010725 4.96 In-house 1-25 (284) Show / Hide 
Range on Protein: 17-41
Range on HMM: 1-25/284
Sequence Identity: 36% (9 aa)

YKLVRKIGSGSFGDVYLGITTTNGE
..| ..||.| ||  ||  ..|...
WRLGKPIGQGGFGCIYLASPNTCKP