Gene CLIK1 (Human)

CLIK1

Species: Human
Alias: STK35, CLIK1
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 20p13,

Classification

Group: Other
Family: NKF4

Sequence

Name Sequence Type Origin Length Description Download
CLIK1.AA Protein Sugen Kinome 534 None Fasta, JSON
CLIK1.kin_dom Protein Kinase Domain Sugen Kinome 329 None Fasta, JSON
CLIK1.NA RNA Sugen Kinome 6683 None Fasta, JSON

Protein domain

Protein domains of CLIK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CLIK1.AA NKF4 202-530 81 2.3e-293 970.75 In-house 1-336 (336) Show / Hide 
Range on Protein: 202-530
Range on HMM: 1-336/336
Sequence Identity: 81% (274 aa)

YSLLAEIGRGSYGVVYEAVAGRSGARVAVKKIRCDAPENVELALAEFWALTSLKRRHQNVVQFEECVLQRNGLAQRMSHGNKSSQLYLRLVETSLKGERI
|.|..||||||||||||||..|..||||||||||.|||||||||.|||||||.||.||||..||||.|||.|..|||||||.||||||.|||||||||||
YDLIREIGRGSYGVVYEAVIRRTSARVAVKKIRCHAPENVELALREFWALTSIKRQHQNVIHFEECILQRDGMVQRMSHGNNSSQLYLQLVETSLKGERI

LGYAEEPCYLWFVMEFCEGGDLNQYVLSRRP--DPATNKSFMLQLTSAIAFLHKNHIVHRDLKPDNILITE-RSGT----PILKVADFGLSKVCAGLAPR
..|..|||||||||.||.|||.|||.|||.|  ...|.||||.||..|.|.||||||.||||||.||.|.| |.|.    |..|||||||||||||||||
FDYPREPCYLWFVMDFCDGGDMNQYLLSRHPRLNDDTYKSFMMQLAQAMAHLHKNHIIHRDLKPYNIIIVEGRKGQSDLEPVVKVADFGLSKVCAGLAPR

GKEGNQDNKNVNVNKYWLSSACGSDFYMAPEVWEGHYTAKADIFALGIIIWAMIERITFIDSETKKELLGTYIKQGTEIVPVGEALLENPKMELHIPQKR
||||.||||||||||.|||.|||.|||||||||||||||||||||||||||||||||||||.||||||||||||||||||||||||||||||||||||||
GKEGQQDNKNVNVNKCWLSTACGTDFYMAPEVWEGHYTAKADIFALGIIIWAMIERITFIDTETKKELLGTYIKQGTEIVPVGEALLENPKMELHIPQKR

RTSMSEGIKQLLKDMLAANPQDRPDAFELETRMDQV
||||.|..|||.|||||||||||||||||||||||.
RTSMNERMKQLIKDMLAANPQDRPDAFELETRMDQI
Kinase CLIK1.AA S_TKc 202-531 21 1.4e-56 195.21 SMART 1-231 (231) Show / Hide 
Range on Protein: 202-531
Range on HMM: 1-231/231
Sequence Identity: 21% (74 aa)

YSLLAEIGRGSYGVVYEAVAGRSGARVAVKKIRCDAPENVELALAEFWALTSLKRRHQNVVQFEECVLQRNGLAQRMSHGNKSSQLYLRLVETSLKGERI
| .| .||.|..|.|| ..  ..| .||.|.|.       | .. |   | .   .| |.|.. ..                                  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK---HHPNIVKLYDVFQD-------------------------------

LGYAEEPCYLWFVMEFCEG--GDLNQYVLSRRP-------DPATNKSFMLQLTSAIAFLHKNHIVHRDLKPDNILITERSGTPILKVADFGLSKVCAGLA
        .|..|||.|.|  ||| .|  .|..       .. . ...| |. .|....|...|.||||||.|||..|      .|..||||...     
-------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL----

PRGKEGNQDNKNVNVNKYWLSSACGSDFYMAPEVWEGHYTA-KADIFALGIIIWAMIERITFIDSETKKELLGTYIKQGTEIVPVGEALLENPKMELHIP
                    .. ||. .||||||   .|.  |.|. ..|.|.. |. . .  .     ..  .. | |                     
--------------------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG---------------------

QKRRTSMSEGIKQLLKDMLAANPQDRPDAFELET-----RMDQVT
       |.  |.... .|  .|..|| | |. .     ....  
-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CLIK1.AA Pkinase 202-523 21 2.4e-50 178.39 Pfam 1-287 (293) Show / Hide 
Range on Protein: 202-523
Range on HMM: 1-287/293
Sequence Identity: 21% (75 aa)

YSLLAEIGRGSYGVVYEAVAGRSGARVAVKKIRCDAPENVELALA----EFWALTSLKRRHQNVVQFEECVLQRNGLAQRMSHGNKSSQLYLRLVETSLK
| ..  ||.||.|.||...   .| .||||.|. .  .  ..  .    |   . .|.  | |.|.. ...                             
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN--HPNIVRLYDWFED---------------------------

GERILGYAEEPCYLWFVMEFCEGG----DLNQYVL---SRRP--DPATNKSFMLQLTSAIAFLHKNHIVHRDLKPDNILITERSGT-PILKVADFGLSKV
          . ....|||.||||    ||  |.    ...   .. . |..|.|. ......|.. |.||||||.|||| ..  . ...|..||||.|.
----------KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQ

CAGLAPRGKEGNQDNKNVNVNKYWLSSACGSDFYMAPEVWE--GHYTAKADIFALGIIIWAMIERITFIDSE----TKKELLGTYIKQGTEIVPVGEALL
                  . |.  ... ||. .||||||     .|. |.|....|.|.. |. . .  ...    .  . .  . . .  ...  .  .
FD----------------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWW

EN------PKMELHIPQKRRTSMSEGIKQLLKDMLAANPQDRPDAFEL
 .      .  . |..... . .||  |...|..|. .|..|| | ..
CSISYFFFRH-W-HFHWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQI
Kinase CLIK1.AA CAMK 207-443 16 1.2e-46 147.96 In-house 1-323 (425) Show / Hide 
Range on Protein: 207-443
Range on HMM: 1-323/425
Sequence Identity: 16% (60 aa)

EIGRGSYGVVYEAVAGRSG------------ARVAVKKIRCD----------------------------APENVELALAEFWALTSLKR-----RHQNV
..||||.|.|....  ...             .||.| |  .                             |.. .  . |   . .|.      .| |.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQFEECVLQRNGLAQRMSHGNKSSQLYLRLVETSLKGERILGYAEEPCY------------LWFVM---EFCEGG----DLNQYVLSRRP----------
... |    ..  .  .                             . |            ...||   |.|.||    || .|. ....          
IKLYEVYEDPHYFK-NT----------------------------ND-YETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDI

------DPATNKSFMLQLTSAIAFLHKNHIVHRDLKPDNILITERSGTP--------------ILKVADFGLSKVCAGLAPRGKEGNQDNKNVNVNKYW-
      . .  . .. |. ||....|...||||||||.|||......                 .|..|||..... .     ..  .....   .. | 
VERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HNQWT

-------LSSACGSDFYMA-PEVWEGH---------------YTAKADIFALGII
       ..  ||.  ||| ||| .|                |. |.|. ..|.|
TPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVI
Kinase CLIK1.AA Ciliate-E2 313-523 21 1.9e-37 126.07 In-house 111-359 (365) Show / Hide 
Range on Protein: 313-523
Range on HMM: 111-359/365
Sequence Identity: 21% (60 aa)

FVMEFCEGGDLNQYVLSR------------RPDPATNKSFMLQLTS---------------AIAFLHKNH-IVHRDLKPDNILITERSGTPILKVADFGL
.|||.|.|||| .|  ..            ...    | .| |...               |. .||... |.|||.||.|||.        .|..||||
LVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF--------IKIIDFGL

SKVCAGLAPRGKEGNQDNKNVNVNK----------------YWLSSACGSDFYMAPEVWEG----------HYTAKADIFALGIIIWAMIERIT-FIDSE
|| .     .. . .| .|.    |                 .  . ||.  |||||. .|          .|. |.||..||.|.  |.   . |    
SKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF----

TKKELLGTYIKQGTEIVPVGEALLENPKMELHIPQKRRT--------------SMSEGIKQLLKD----MLAANPQDRPD-AFEL
                      . .. . .. .|..  .              . |.  |.|.|     ||  .|. |.. . ..
----------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQI
Kinase CLIK1.AA CAMKL 202-443 23 1e-36 114.63 In-house 1-225 (297) Show / Hide 
Range on Protein: 202-443
Range on HMM: 1-225/297
Sequence Identity: 23% (65 aa)

YSLLAEIGRGSYGVVYEAVAGRS-GARVAVKKIR----CDAPENVELALA-----------EFWALTSLKRR-HQNVVQFEECV-----LQRNGLAQRMS
| .. ..|.||.|.|  |.  |  | .||.| |     .. | .    .            |   . .|. . |.|.... |..                
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHD----------

HGNKSSQLYLRLVETSLKGERILGYAEEPCYLWFVMEFCEGGD--LNQYVLSR-----RPDPATNKSFMLQLTSAIAFLHKNHIVHRDLKPDNILITERS
                          |   ... ||| |.||.  | .|. ..     | ..   . .  |. ||....|...|||||.||.|||..|. 
-------------------------IET-KKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENG

GTPILKVADFGLSKVCA-GLAPRGKEGNQDNKNVNVNKYWLSSACGSDFYMAPEVWEG---HYT-AKADIFALGII
    .|..|||.|  .  .              .. .   |.  |||  |||||. .|   .|   |.|| ..|.|
NN-NIKIIDFGFSNMYRPC--------------IFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVI
Kinase CLIK1.AA TKL 300-527 18 3.3e-36 126.63 In-house 89-364 (364) Show / Hide 
Range on Protein: 300-527
Range on HMM: 89-364/364
Sequence Identity: 18% (57 aa)

RILGYAEEPCY-------------LWFVMEFCEGGDLNQYVLSRRPDPATNKSFMLQLTSAIAFLHKNH--------IVHRDLKPDNILITERSG-----
...||. .| .             |..|||.|.||.|  |..     .    ...|.  .....|| ..        |.|||||..|||. |        
QFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNY

-----TPI-LKVADFGLSKVC----------------AGLAPRGKEGNQDNKNVNVNKYW------LSSACGSDFYMAPEVWEGH---------------
      .. .|..|||||..                 |                  .         ... ||.  .||||| .|.               
MYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESA------------------E--HQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKG

--YTAKADIFALGIIIWAMIERITFIDSETKKELLGTYIKQGTEIVPVGE-------ALLENPKMELHIPQKRR--------TSMSEGIKQLLKDMLAAN
  |. |.|... ||..| .. | .               ..  .. ...        ..  . .. . ||   .        ... ...|.|..|  ...
FEYSEKCDVYSFGIVLWEILTRCR-------------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHD

PQDRPDAFELETRM
|..|| . |.  |.
PEKRPSFQEILKRL
Kinase CLIK1.AA STE 202-449 18 6.7e-35 120.7 In-house 1-263 (359) Show / Hide 
Range on Protein: 202-449
Range on HMM: 1-263/359
Sequence Identity: 18% (58 aa)

YSLLAEIGRGSYGVVYEAVAG------RSGAR---------VAVKKIRCDAP-----------------ENVELALAEFWALTSLK-RRHQNVVQFEECV
. .. .||.|..|.|| |.        ..|           .|.|... .                   |...  | |   .  ..   |.|.|..  | 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHM-HPNIVKYYGCY

LQR--NGLAQRMSHGNKSSQLYLRLVETSLKGERILGYAEEPCYLWFVMEFCEGGDLNQYVLSR----RPDP-----------ATNKSFMLQLTSA-IAF
..   |                                 ..  .|| .||...|| | . . ..    .|..              . .  |.  .  ..
FKEGHN--------------------------------HKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYY

LHKNHIVHRDLKPDNILITERSGTPILKVADFGLSKVCAGLAPRGKEGNQDNKNVN----VNKYWLSSACGSDFYMAPEVWEG-------HYTAKADIFA
||..||.|||.||.|||.         | .|||...  .   ... . . .| . .     ..    . .|.  .||||| ..       .|..|.||  
LHSHHIIHRDIKPANILL--------VKLCDFGVCGQLTDSMANI-Q-S-NN-I-IDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWS

LGIIIWAMIE
||. |. |..
LGCTIIEMAT
Kinase CLIK1.AA CMGC 202-448 19 1.1e-33 107.41 In-house 1-329 (513) Show / Hide 
Range on Protein: 202-448
Range on HMM: 1-329/513
Sequence Identity: 19% (70 aa)

YSLLAEIGRGSYGVVYEAVAGRSGAR--------------VAVKKIRCDAPENVE------------LALAEFWALTSLK---------------RRHQN
|  .  ||.|.|||||...  |.. .              ||.|||. .  .  .             || |   |  |.               . | |
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

VVQFEECVLQRN---------GLAQRMSHGNKSSQLYLRLVETSLKGERILGYAEEPC---YLWFVMEFCEGGDLNQYVLSRR----------PDPAT--
.|.  ...  .|         ..                          |  .        .| .|.|...  || ||  . .           ..    
IVKLYDIFYHKNSDGNEYEDKHI--------------------------I--S----QHFNHLYLVFEYMDH-DLYQYIKNNQFDYQGKRPMPLSE-HEN

----------NKSFM------LQLTSAIA--FLHKNH--IVHRDLKPDNILITERSGT-----------------PILKVADFGLSK-VCAGLAPRGKEG
           |.||       |.  ...  ..|..   |.|||||| ||||...                     .||..||||.. .     ..... 
KHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQ

NQDNKNVNVNKYW----LSSACGSDFYMAPEVWEGH-----------YTAKADIFALGIIIWAMI
 |  |||| ..      ...   . .| |||.  |            || . |. ..| |.  |.
PQSFKNVNKDD-KPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMY
Kinase CLIK1.AA TK 202-445 12 2.3e-31 101.81 In-house 1-385 (486) Show / Hide 
Range on Protein: 202-445
Range on HMM: 1-385/486
Sequence Identity: 12% (56 aa)

YSLLAEIGRGSYG---VVYEAVAGRSG-------------------------ARVAVKKIRCDAPENVELALA-------------EFWALTSLKRR---
  |. ..|.| .|   .||.. . . .                          .|||| .. ..... |  ..             |...  .. ..   
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HQNVVQFEECVLQR------NGLAQRMSHGNKSSQLYLRLVETSLKGERILGYAEEPCYLWFVMEFCEGGD----LNQYVLSRRPDPATNKS-------
 |.|.|..  ...|       .                             . .  .   .. |||....||    | .|  ..||.  .. .       
HHPNIVRLYGVCTQGEPKPCFE-----------------------------V-V-VHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHN

---------------------------------------------------------------------FMLQLTSAIAFLHKN------HIVHRDLKPD
                                                                     ...|. .. ..||..      ..|||||   
KYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAAR

NILITERSG--------TPILKVADFGLSKVCAGLAPRGKEGNQDNKNVNVNKYWLSSACGSDFY-----------------------------------
|.|..|.          .|. |.||||||...  .                           | |                                   
NCLVGENNVCKWHFDGCGPVCKIADFGLSRQGS-G-----------------------VLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGG

------MAPEVWE----------GHYTAKADIFALGIIIW
      ||||...          |..| | |....|. .|
KLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMW
Kinase CLIK1.AA ULK 306-387 31 6.2e-27 91.12 In-house 88-191 (329) Show / Hide 
Range on Protein: 306-387
Range on HMM: 88-191/329
Sequence Identity: 31% (33 aa)

EEP--CYLWFVMEFCEGGDLNQYVLSRRPDPATN-----------KSFMLQLTSAIAFLHKNHIVHRDLKPDNILITERSGT---------PILKVADFG
|..  ......||.|.|||| ||   ... | .            ..|. |. ..  .|||. |.|||.||.||||..  .          ..||.||||
ETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFG

LSKV
..|.
FAKH
Kinase CLIK1.AA ULK 310-387 32 5.5e-26 89.23 In-house 91-187 (324) Show / Hide 
Range on Protein: 310-387
Range on HMM: 91-187/324
Sequence Identity: 32% (32 aa)

YLWFVMEFCEGGDLNQYVLSRRPDPATN-----------KSFMLQLTSAIAFLHKNHIVHRDLKPDNILITERSGT---------PILKVADFGLSKV
.....||.|.|||| ||   ... |              ..|. |. ..  .|||. |.|||.||.||||..  .          ..||.||||..|.
NIYIIMEYCNGGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKH
Kinase CLIK1.AA TyrKc 202-527 20 4.6e-15 20.92 SMART 1-280 (280) Show / Hide 
Range on Protein: 202-527
Range on HMM: 1-280/280
Sequence Identity: 20% (70 aa)

YSLLAEIGRGSYGVVYEAVAGRSGARVAVKKIRCDAPENVELALAEFWALTSL-KRRHQNVVQFEECVLQRNGLAQRMSHGNKSSQLYLRLVETSLKGER
 .|. ..|.| .|.||....      ||||... ||   .|  . |   ...| . .|.|.|                                     |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGG-HHPNIV-------------------------------------R

ILGYAEEP-------CYLWFVMEFCEGGDLNQYVLSRR--PDPATNKSFMLQLTSAIAFLHKNHIVHRDLKPDNILITERSGTPILKVADFGLSKVCAGL
..|.. ..         |. |||....|||..|  ..|    ...  ||..|  .  ..||.....||||   |.|..|.    . |..|||||.     
LYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDD

------APRGKEGNQDNKN--VNVNKYWLSSACGSDFYMAPEVW-EGHYTAKADIFALGIIIWAMIERITFIDSE-----TKKELLGTYIKQGTEIVPVG
          .    ....  . .              ||||.. .| .| | |... |. .| .  .     ..      . . .  |.|||    .  
DQQGESKDYYRKKEHKGGKTMLPI------------RWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPP

EALLENPKMELHIPQKRRTSMSEGIKQLLKDMLAANPQDRPDAFELETRM
...   | |           ... . |. |.  ...| |||   |.  ..
NDY---P-MSF-------VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase CLIK1.AA Pkinase_Tyr 310-386 26 1.6e-14 49.8 Pfam 81-159 (270) Show / Hide 
Range on Protein: 310-386
Range on HMM: 81-159/270
Sequence Identity: 26% (22 aa)

YLWFVMEFCEGGDLNQYVLSR-----RPDPATNKSFMLQLTSAIAFLHKNHIVHRDLKPDNILITERSGTPILKVADFGLSK
... |||....|||  |  ..     .... .  .. .|  .. ..|. ....||||   |.|.||   . . |..||||..
QIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE---NNVVKICDFGLAR
Kinase CLIK1.AA ULK 416-448 38 5.7e-09 27.53 In-house 212-250 (329) Show / Hide 
Range on Protein: 416-448
Range on HMM: 212-250/329
Sequence Identity: 38% (15 aa)

CGSDFYMAPEVWEGH-----YT-AKADIFALGIIIWAMI
||.  ||||....|.     |. .|.||. ||.|.  |.
CGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEML
Kinase CLIK1.AA ULK 414-448 29 2e-08 26.07 In-house 200-246 (324) Show / Hide 
Range on Protein: 414-448
Range on HMM: 200-246/324
Sequence Identity: 29% (14 aa)

SAC------GSDFYMAPEVWEGH-----YT-AKADIFALGIIIWAMI
...      |.  ||||....|.     |. .|.||. ||.|.  |.
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEML
Kinase CLIK1.AA TKL 208-264 25 5.4e-08 24.88 In-house 1-90 (364) Show / Hide 
Range on Protein: 208-264
Range on HMM: 1-90/364
Sequence Identity: 25% (23 aa)

IGRGSYGVVYEA-VAG-------RSGARVAVKKIRCD------------------------APENVELALAEFWALTSLKR-RHQNVVQF
||.|..|.|| .   |       ..|  |||||.. .                        .||.  .   |   . ...| ||.|.|||
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQF
Kinase CLIK1.AA ULK 202-267 24 8.7e-07 20.18 In-house 1-83 (324) Show / Hide 
Range on Protein: 202-267
Range on HMM: 1-83/324
Sequence Identity: 24% (20 aa)

YSLLAEIGRGSYG-VVYEAVAGRS---GARVAVKKIR----CDAPENVE------LALAEFWALTSLKR-RHQN--VVQFEEC
|.|  ..| ||.| .||..   ..   .  ||.|.|      . . . |      |   |   .  ||. .|.|  .|.. ..
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDW
Kinase CLIK1.AA ULK 202-267 24 1e-06 19.59 In-house 1-86 (329) Show / Hide 
Range on Protein: 202-267
Range on HMM: 1-86/329
Sequence Identity: 24% (21 aa)

YSLLAEIGRGSYGVVYEAVAGRS----GARVAVKKIR---CDAPENV-------ELALAEFWALTSLKR--RHQN----VVQFEEC
|.|  ..| ||.|.||..   ..    .  ||.|.|    ..  .|        .|   |   .  ||.  ||.|    .|.. ..
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDW
Kinase CLIK1.AA Pkinase_Tyr 202-239 23 4e-06 21.52 Pfam 1-42 (270) Show / Hide 
Range on Protein: 202-239
Range on HMM: 1-42/270
Sequence Identity: 23% (10 aa)

YSLLAEIGRGSYGVVYEAVAG----RSGARVAVKKIRCDAPE
 ... ..|.|..|.||....       .  ||||... .| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMH
Kinase CLIK1.AA Ciliate-E2 202-219 38 0.00091 8.79 In-house 1-18 (365) Show / Hide 
Range on Protein: 202-219
Range on HMM: 1-18/365
Sequence Identity: 38% (7 aa)

YSLLAEIGRGSYGVVYEA
| ..  ||.|..|.||..
YKFIKKIGQGNFGSVYKC
Kinase CLIK1.AA CAMKL 497-524 28 0.0129 4.0 In-house 266-292 (297) Show / Hide 
Range on Protein: 497-524
Range on HMM: 266-292/297
Sequence Identity: 28% (8 aa)

SMSEGIKQLLKDMLAANPQDRPDAFELE
..|   ..|.. ||  || .|| . ...
HVS-DCRDLIRKMLQVNPEKRPTIHQIM
Kinase CLIK1.AA TK 498-527 23 0.020847 3.02 In-house 457-486 (486) Show / Hide 
Range on Protein: 498-527
Range on HMM: 457-486/486
Sequence Identity: 23% (7 aa)

MSEGIKQLLKDMLAANPQDRPDAFELETRM
. | . .|...  ...|.|||.  .|  ..
PPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase CLIK1.AA CAMK 499-522 29 0.129542 0.16 In-house 395-418 (425) Show / Hide 
Range on Protein: 499-522
Range on HMM: 395-418/425
Sequence Identity: 29% (7 aa)

SEGIKQLLKDMLAANPQDRPDAFE
|.  |.|.. ||  .|..|. . .
SQECKDLIRKMLQVDPEKRMTIEQ
Kinase CLIK1.AA STE 496-523 28 0.329834 0.17 In-house 324-351 (359) Show / Hide 
Range on Protein: 496-523
Range on HMM: 324-351/359
Sequence Identity: 28% (8 aa)

TSMSEGIKQLLKDMLAANPQDRPDAFEL
...|.  |. ..  |  .|..||.| .|
HKWSPEFKDFINKCLQKDPNKRPTASQL