Gene CTK (Human)

CTK

Species: Human
Alias: HYLTK, MGC2101, CHK, HYL, Lsk, DKFZp434N1212, MGC1708, MATK, HHYLTK, CTK
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 19p13.3,

Classification

Group: TK
Family: Csk

Sequence

Name Sequence Type Origin Length Description Download
CTK.NA RNA Sugen Kinome 2104 None Fasta, JSON
CTK.AA Protein Sugen Kinome 508 None Fasta, JSON
CTK.kin_dom Protein Kinase Domain Sugen Kinome 244 None Fasta, JSON

Protein domain

Protein domains of CTK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH3 CTK.AA SH3 52-110 27 1.6e-10 42.17 SMART 1-58 (58) Show / Hide 
Range on Protein: 52-110
Range on HMM: 1-58/58
Sequence Identity: 27% (16 aa)

TQCITKCEHTRPKPGELAFRKGDVVTILEACENKSWYRVKHHTSGQEGLLAAGALRERE
 ... .. ..   |.|| |.|||..|.|| . .  |........||||.  .  ..| .
PYVRALYDYQAQNPDELSFKKGDIITVLEKD-DDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_1 CTK.AA SH3_1 65-100 36 1e-05 22.44 Pfam 11-46 (49) Show / Hide 
Range on Protein: 65-100
Range on HMM: 11-46/49
Sequence Identity: 36% (13 aa)

PGELAFRKGDVVTILEACENKSWYRVKHHTSGQEGL
|.|| |.|||.....|  ... |.... ...||||.
PDELSFKKGDIIHVIEKSDDWDWWKGRCNNTGQEGW
SH3_2 CTK.AA SH3_2 53-88 20 0.000882 16.13 Pfam 1-45 (68) Show / Hide 
Range on Protein: 53-88
Range on HMM: 1-45/68
Sequence Identity: 20% (9 aa)

QCITKCEHTR-PKPGE-----LAFRKGDVVTIL---EACENKSWY
 ... |...  ....|     | |.||||....   .   ...|.
YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWDNWWW
SH2 CTK.AA SH2 123-197 45 1.1e-38 115.45 Pfam 1-81 (81) Show / Hide 
Range on Protein: 123-197
Range on HMM: 1-81/81
Sequence Identity: 45% (37 aa)

WFHGKISGQEAVQQLQP--PEDGLFLVRESARHPGDYVLCVSFGR---DVIHYRVLHRDG-HLTIDEAVFFCNLMDMVEHY
|.|||||.||| ..|.   ..|| |||||| ..||||.|.| ..     | |||.   |. .. | . . ||.|...||||
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 CTK.AA SH2 121-203 43 3.8e-33 117.37 SMART 1-87 (87) Show / Hide 
Range on Protein: 121-203
Range on HMM: 1-87/87
Sequence Identity: 43% (38 aa)

MPWFHGKISGQEAVQQLQP--PEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLHRD-GHLTIDE--AVFFCNLMDMVEHYSKDKGA
.||.||.||..||.| |.   ..|| ||||.| ..||||||.| ... | |||. . | |   |||   . |..| ..|.||.. .. 
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase CTK.AA Csk 236-479 63 1.6e-192 645.86 In-house 1-251 (251) Show / Hide 
Range on Protein: 236-479
Range on HMM: 1-251/251
Sequence Identity: 63% (160 aa)

LTLGAQIGEGEFGAVLQGEYLGQKVAVKNIKCD--VTAQAFLDETAVMTKMQHENLVRLLGVILHQG--LYIVMEHVSKGNLVNFLRTRGRALVNTAQLL
|.||..||.||||.|.||||...|||||.||||  ..|||||.|..|||...|.|||.|.||||||.  ||||||..||||||..||.|||......|||
LHLGECIGHGEFGDVMQGEYQNRKVAVKCIKCDGNGMAQAFLAEASVMTQLRHPNLVQLIGVILHQKNHLYIVMEYMSKGNLVDYLRSRGRHVITRRQLL

QFSLHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLD---SSRLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPK
.|...|.|||.|||.||.|||||||||||||||.|||||||||||.|....|   |...|.||||||||.|.||..||||||||.||||..|.||.|||.
KFAMDVCEGMCYLEQKKFVHRDLAARNILVSEDCVAKVSDFGLAKEECSQQDDSTSGKFPIKWTAPEALRHKKFSTKSDVWSFGILLWEIYSFGRVPYPR

MSLKEVSEAVEKGYRMEPPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKL
..||.|...||||||||.|||||..|. .|..||...||.||.||...|.|
IPLKDVVKHVEKGYRMEAPEGCPPHVYKVMKQCWHLNPAKRPTFRQVREQL
Kinase CTK.AA Pkinase_Tyr 236-479 43 8.99999999999e-133 450.29 Pfam 1-270 (270) Show / Hide 
Range on Protein: 236-479
Range on HMM: 1-270/270
Sequence Identity: 43% (118 aa)

LTLGAQIGEGEFGAVLQGEYL------GQKVAVKNIKCDVTAQA-----FLDETAVMTKM-QHENLVRLLGVIL-HQG---LYIVMEHVSKGNLVNFLRT
.|.| ..|||.|| | .|..       ...|||| .| . . ..     |. | ..|... .|.|.|||.||.. ...   .|||||.. .|.| ..||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

R--GRALVNTAQLLQFSLHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAE-------RKGLDSSRLPVKWTAPEALKHGKFTSKSDVWS
.  ..  ... .|||... .|.||||||||...||||||||.||.|..|.|..|||||..        ||. ..  ||.||.|||....||||.||||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKSDVWS

FGVLLWEVFSYGRAP-YPKMSLKEVSEAV-EKGYRMEPPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKL
||||.||.|.||. | || ||  || |.. |.||||..||.|| ... || .||...|..|| |. . |.|
FGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase CTK.AA TyrKc 236-479 39 1.2e-131 444.61 SMART 1-280 (280) Show / Hide 
Range on Protein: 236-479
Range on HMM: 1-280/280
Sequence Identity: 39% (112 aa)

LTLGAQIGEGEFGAVLQGEYLGQKVAVKNIKCDVTAQAFLDETAVMTKM--QHENLVRLLGVILH--------QGLYIVMEHVSKGNLVNFLRTRGRALV
.||| ..|||.|| | .|..  ..|||| .| |   ..|..|  .|.|   .|.|.|||.||...        . |.||||....|.| ..|| ...  .
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK-L

NTAQLLQFSLHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKG--------LDS------SR--LPVKWTAPEALKHGKFTSKSDVW
....||.|.. .|.|||||.||...||||||||.||.|....|.|||||...   .          .      ..  ||..|.|||....||||.|||||
CMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVW

SFGVLLWEVFSYGRAPYPK-----MSLKEVSEAVEKGYRMEPPEG--------CPGPVHVLMSSCWEAEPARRPPFRKLAEKL
||||..||.|.||  |||      || .|| | |..||||..|.         ||  .. .|..||...|. || |. . |..
SFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase CTK.AA TK 236-479 24 4e-113 380.74 In-house 1-486 (486) Show / Hide 
Range on Protein: 236-479
Range on HMM: 1-486/486
Sequence Identity: 24% (118 aa)

LTLGAQIGEGEFG---AVLQGEYLG---------------------------QKVAVKNIK--CDVTAQAFLD--------------ETAVMTKMQ----
.||| ..|||.||    | .||. |                           ..|||| .|  .. ....|.|              | ..| .|.    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HENLVRLLGVILHQG-------------LYIVMEHVSKGN----LVNFLRTRG----------------------------------------------
 |.|.|||.||.....             ..||||....|.    | ..||..                                               
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------------------------RALVNTAQLLQFSLHVAEGMEYLESK------KLVHRDLAARNILVSEDLV-----------AKVSDFGLA-
                            .. ....||| ... .|.|||||.||      ..|||||||||.||.|..|           .|..||||. 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----KAERKGLD-------------------------------SSRLPVKWTAPEALK---------HGKFTSKSDVWSFGVLLWEVFSYGRAPYPK-M
      | . . |                               . .||..|.|||.|.         .||||.||||||||||.||.|.||..||.  |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

SL---------KEVSEAVEKG--------------YRMEPPEGCP--------------GPVHVLMSSCWEAEPARRPPFRKLAEKL
|          .|| | ...|              .||..|..||                .. || .||...|..|| |. | |.|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase CTK.AA Src 236-479 44 7.29999999999e-109 367.97 In-house 1-255 (255) Show / Hide 
Range on Protein: 236-479
Range on HMM: 1-255/255
Sequence Identity: 44% (113 aa)

LTLGAQIGEGEFGAVLQGEYLG-QKVAVKNIKCD-VTAQAFLDETAVMTKMQHENLVRLLGVILHQ-GLYIVMEHVSKGNLVNFLR-TRGRALVNTAQLL
..|  ..|.| || | .| . |  ||||| .| .    .||| |  .|.|..||.||.|. |       ||| |  |.|.|  .|. ..    ..  ||.
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI

QFSLHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKG------LDSSRLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFSYGRAP
 .. .|||||.||||....||||||||.||.|..|.|| |||||.   ..         ...|.|||||||. .|.|| ||||||||.||.|...||| |
DMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVP

YPKMSLKEVSEAVEKGYRMEPPEGCPGPVHV-LMSSCWEAEPARRPPFRKLAEKL
|| |. .|| ..||.||||  |..||  ..  .|  ||...| .|| |  | ..|
YPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase CTK.AA UTK 236-479 33 1.9e-100 340.03 In-house 1-296 (296) Show / Hide 
Range on Protein: 236-479
Range on HMM: 1-296/296
Sequence Identity: 33% (99 aa)

LTLGAQIGEGEFGAVLQGEYL-----GQKVAVKNIKCD-----VTAQA----FLDETA---VMTKMQ-HENLVRLLGVILHQG-LYIVMEHVSKGNLVNF
. ||.|.|.|.|| |  ...      .....|.. .|.      ....    |. |..   .| . . |.|..||.|| . .. ..||.|. ..|.|...
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LRTRGR------ALVNTAQLLQFSLHVAEGMEYLESKKLVHRDLAARNILVSED-------LVAKVSDFG---LAKAER--------------KGLDSSR
||. ..      ....  |.|......|.||.||.|...|||||||||.|| ..       .|.|..|||   ....                .  .  |
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

LPVKWTAPEALKHG-KFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKG--YRMEPPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKL
.|..|.||||| |. .||.|||||||||..||....||.||| ||  .| ..|..|  |||..|..|| ||  || .||...|..|| |. | ...
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase CTK.AA TK-Unique 236-479 39 5.2e-93 315.3 In-house 1-294 (294) Show / Hide 
Range on Protein: 236-479
Range on HMM: 1-294/294
Sequence Identity: 39% (116 aa)

LTLGAQIGEGEFGAVLQGEYLG--------QKVAVKNIK---CDVTAQAFLDETAVMTKMQ-HENLVRLLGVILHQG--LYIVMEHVSKGNLVNFLRTRG
|..| .||||.|| |  ||. |        ..||||  |    |.. |.||.| ..| .   |.|.|..||.    .   .|.||....||| ..|||..
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

RA------------------------LVNTAQLLQFSLHVAEGMEYLES--KKLVHRDLAARNILVSEDLVAKVSDFGLAK------AERKGLDSSRLPV
.|                         ..  .|..|   .| |||||.|  || |||||.|||.|..||.|.|..|||.|.      .  .   ..|.|.
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

KWTAPEALK--HGKF-TSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRMEPPEGC-PGPVHVLMSSCWEAEPARRPPFRKLAEKL
.| |||.||  || . |.||||||||||.||.|..|  |||.|. |.. |....||||. ||.| .  .. ||.|||  ||  || ||... .|
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase CTK.AA Fer 236-480 33 3.4e-91 309.29 In-house 1-283 (283) Show / Hide 
Range on Protein: 236-480
Range on HMM: 1-283/283
Sequence Identity: 33% (94 aa)

LTLGAQIGEGEFGAVLQGE-----YLG-----QKVAVKNIKC---DVTAQ---AFLDETAVMTK-MQHENLVRLLGVILHQG-LYIVMEHVSKGNLVNFL
 ||| ..||| || | .|.     ..|      |||||  ||   |.|.     |. |. .| . ..| | |.. ||. ..  ..|||| .. |.| ..|
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

RTRGRALVNTAQLLQFSLHVAEGMEYLESKKLVHRDLAARNILVSE-DLVAK--VSDFGLAKAERKGLDSSR-------LPVKWTAPEALKHGKFTSKSD
.. .  .| ...........| |||||.||. .|||.||||.|... ... |  .||||........  ...       .|..|.|||... | ...|.|
KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTD

VWSFGVLLWEVFSYGRAPYPK----MSLKEV----SEA-VEKGYRMEPPEGCPGPVHVLMS-SCWEAEPARRPPFRKLAEKLA
||||||..||.|. |  |||     | ...|     .. ..|||.| .|...| ..  .|  .||...|  || . .. .|| 
VWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase CTK.AA SRM 236-480 43 5.7e-89 297.75 In-house 1-253 (253) Show / Hide 
Range on Protein: 236-480
Range on HMM: 1-253/253
Sequence Identity: 43% (109 aa)

LTLGAQIGEGEFGAVLQGEYLGQ-KVAVKNIKCDV--TAQAFLDETAVMTKMQHENLVRLLGVI-LHQGLYIVMEHVSKGNLVNFLRTRGRALVNTAQLL
 ||.   ||| || |  |  .|| .||.| || |     . .  |   | |. |. ..||  |. .    ||. |   ||||  .||.         .||
FTLCRKLGEGYFGEVWEGLWKGQVHVAIKVIKRDNLMHQHMLQKEIQAMKKLRHKHIIRLHAVCSVGDPVYIITELMRKGNLQQYLRDSDEKALPIPHLL

QFSLHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLD----SSRLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYP
 |   ||||| |||... .||||||||.|| .... || |||||   .        ... |.|||||||.  . .  ||||||||.||.|.|.||  |||
DFACQVAEGMCYLEEQNYIHRDLAARNVLVGDNNLCKVGDFGLARLIKDDIYSPSHDHNIPYKWTAPEAANYRHYSQKSDVWSFGILLHEMFTYGQCPYP

KMSLKEVSEAVEKGYRMEPPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKLA
 |.  |    ...||||  |  ||  ||.|| .||. .|  || |. | |||.
GMTNHETFQQIDRGYRMPCPAECPPEVHKLMLECWCRDPEQRPCFKDLREKLT
Kinase CTK.AA Tec 236-481 42 1.2e-88 300.86 In-house 1-254 (254) Show / Hide 
Range on Protein: 236-481
Range on HMM: 1-254/254
Sequence Identity: 42% (108 aa)

LTLGAQIGEGEFGAVLQGEYLGQ-KVAVKNIK-CDVTAQAFLDETAVMTKMQHENLVRLLGVILHQG-LYIVMEHVSKGNLVNFLRTRGRALVNTA-QLL
||.   .| | || |  |.. .| .||.| ||        |..|  ||.| .|..||.| || . |  .||| | ...| | |.||...  .      ||
LTFMKELGSGQFGVVHLGKWRHQYDVAIKMIKEGSMSEEDFIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHFQKNMAILL

QFSLHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLD----SSR---LPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFSYGRA
.  . | |||.|||... .|||||||| ||... | ||||||..   |  ||    ||     |||| .|| ..  .. ||||||.|||| ||||| |..
EMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMT---RYVLDDQYTSSVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKM

PYPKMSLKEVSEAVEKGYRMEPPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKLAR
||..||  || |.| .|.|.. |. |.  .   | .||. .|  ||.|..| .... 
PYENMSNSEVVEHVSQGHRLYRPHLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE
Kinase CTK.AA Abl 236-479 43 2.4e-87 291.41 In-house 1-252 (252) Show / Hide 
Range on Protein: 236-479
Range on HMM: 1-252/252
Sequence Identity: 43% (110 aa)

LTLGAQIGEGEFGAVLQGEY--LGQKVAVKNIKCD-VTAQAFLDETAVMTKMQHENLVRLLGVILHQG-LYIVMEHVSKGNLVNFLRTRGRALVNTAQLL
...  ..| | .| | .| .   .. |||| .| | .  . || | |.| .|.|.|||.||||  .    ||. |....|||...||  .| ...   ||
IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKEDTMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELPAVVLL

QFSLHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGL----DSSRLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYP
.    .| ||.|||... .|||||||| ||.|. . || |||||.  ..         . |.||||||.| . || |||||| |||||||.  || .|||
YMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKDDTYTAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGMSPYP

KMSLKEVSEAVEKGYRMEPPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKL
 . |..| . .||||||| |||||  |  ||  ||. ... || |... ...
GIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase CTK.AA SrcB 236-480 44 1.6e-82 278.94 In-house 1-251 (251) Show / Hide 
Range on Protein: 236-480
Range on HMM: 1-251/251
Sequence Identity: 44% (112 aa)

LTLGAQIGEGEFGAVLQGEYLGQ-KVAVKNIK-CDVTAQAFLDETAVMTKMQHENLVRLLGVILHQGLYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQF
| |  ..| | || |  | | .. ||||| .|   .  .|||.|  || ..||. ||||  |. .  .||. |.. || |. ||.|   . ..  .|. .
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVTKEPIYIITEYMAKGCLLDFLKTDEGSKLSLPKLIDM

SLHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAK----AERKGLDSSRLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKM
|  .|||| |.| .  .|||| | |||||| |. |. |||||.     |    .  . |.|||||||...| || ||||||||.|| |.  ||| ||| |
SAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYPGM

SLKEVSEAVEKGYRMEPPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKLA
.  || ...|.||||  |. ||  .  .|  ||   |  || |  |   | 
TNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase CTK.AA S_TKc 236-480 24 3.9e-46 160.49 SMART 1-231 (231) Show / Hide 
Range on Protein: 236-480
Range on HMM: 1-231/231
Sequence Identity: 24% (63 aa)

LTLGAQIGEGEFGAVLQGEYLG--QKVAVKNIKCDVTAQAFLDETAVMTKMQHENLVRLLGVILHQGLYIVMEHVSK--GNLVNFLRTRGRAL----VNT
 ... .||.| || | ..   .  ..||.| ||     . .. | ... | .|.|.|.|..|. .. ||.|||...   |.|  ... |||       . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE

AQLLQFSLHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSRLPVKWTAPEALKHGKFTS-KSDVWSFGVLLWEVFSYGRAPY
 .   .   .....||. |.. .||||   |||..|  . |..|||||.      ..      . ||| |   ...  |.|.||.|..|.| .. |. |.
-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPPF

PKMSLKEVSEAVEKGYRMEPPEGCPGPVHVLMSSCWEAEPARRPPFRKLAE--------KLA
|   .... . .            . ..  ... |.. .|..||   .. .           
P--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CTK.AA Pkinase 236-427 27 4.5e-34 121.55 Pfam 1-213 (293) Show / Hide 
Range on Protein: 236-427
Range on HMM: 1-213/293
Sequence Identity: 27% (59 aa)

LTLGAQIGEGEFGAVLQGEYLGQK--VAVKNIKCDVTAQAFLD------ETAVMTKMQHENLVRLLGVIL-HQGLYIVMEHVSKG----NLVNFLR-TRG
...| .||.| || | ..   |    |||| || . .   ..       | ..| ...|.| |||...   .. .|.|||.. .|     |  ...  |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RAL-VNTAQLLQFSLHVAEGMEYLESKKLVHRDLAARNILVSEDLVA----KVSDFGLA----KAERKGLDSSRLPVKWTAPEALK-HGKFTSKSDVWSF
...     ..  . . ...|.||. |.. .||||   |||.... .     |..|||||          ...      . ||| .. . . ..|.|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVLLWEVFSYGRAPYP
|..|.|... || |.|
GCILYEMLC-GRPPFP