Gene MAP3K7 (Human)

MAP3K7

Species: Human
Alias: bA723P2.3, FLJ16518, MAP3K7, MAP3K15
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: Xp22,

Classification

Group: STE
Family: STE11
Subfamily: ASK

Sequence

Name Sequence Type Origin Length Description Download
MAP3K7.NA RNA Sugen Kinome 4633 None Fasta, JSON
MAP3K7.AA Protein Sugen Kinome 1313 None Fasta, JSON
MAP3K7.kin_dom Protein Kinase Domain Sugen Kinome 260 None Fasta, JSON

Protein domain

Protein domains of MAP3K7.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
ASK_nterm_v5 MAP3K7.AA ASK_nterm_v5 102-156 63 1.1e-31 111.59 In-house 1-55 (55) Show / Hide 
Range on Protein: 102-156
Range on HMM: 1-55/55
Sequence Identity: 63% (35 aa)

PFGELDFGETAVLDAFYDADVAVVDMSDVSRQPSLFYHLGVRESFDMANNVILYH
.|..||||||...| || |||..||||.  .||.||||||||.||.|.||.||| 
EFMRLDFGETDMFDEFYNADVVIVDMSIDHQQPNLFYHLGVRHSFKMRNNIILYC
TPR_ASK_1 MAP3K7.AA TPR_ASK_1 282-315 50 8.6e-20 65.28 In-house 1-38 (38) Show / Hide 
Range on Protein: 282-315
Range on HMM: 1-38/38
Sequence Identity: 50% (19 aa)

SDIIINLLLSYRDIQDYDAMVKLVETLE---MLPTC-D
.||..|...|||||||||.|..|||.|.    .|.| .
GDIVHNFMHSYRDIQDYDSMIELVEDLKEGEHIPNCCK
TPR_ASK_2 MAP3K7.AA TPR_ASK_2 358-400 60 2.4e-29 92.74 In-house 1-46 (46) Show / Hide 
Range on Protein: 358-400
Range on HMM: 1-46/46
Sequence Identity: 60% (28 aa)

PDMFCLCGRIYKDIFLDSDCKD---DTSRDSAIEWYRKGFELQSSL
|||.|.|||||||.||.|.. |    .|||.||.|||||||.| ..
PDMWCMCGRIYKDMFLESQYTDEAARESRDQAIHWYRKGFEIQPNH
TPR_ASK_3 MAP3K7.AA TPR_ASK_3 446-479 58 1.5e-14 53.7 In-house 1-34 (34) Show / Hide 
Range on Protein: 446-479
Range on HMM: 1-34/34
Sequence Identity: 58% (20 aa)

YWDVGQFFSVSMLAHDVGKAVQAAERLFKLKPPV
||||. || .| || |  |..||.| .||||||.
YWDVATFFEISILACDYHKCMQACECMFKLKPPN
Kinase MAP3K7.AA ASK 657-908 85 3.6e-193 648.01 In-house 1-254 (254) Show / Hide 
Range on Protein: 657-908
Range on HMM: 1-254/254
Sequence Identity: 85% (216 aa)

VLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKYLKHRNIVQYLGSVSENGYIKIFMEQVPGGSLSALLRSKWGPMK--EPTIKFYT
|||||||||||||||...||||||||||||||||.|||||||||||.|.|||||||||..|||||.||||||||||||||||||||||||  | |..|||
VLGKGTYGIVYAGRDMHTQVRIAIKEIPERDSRYVQPLHEEIALHKQLRHRNIVQYLGCCSENGYFKIFMEQVPGGSLSALLRSKWGPMKDNENTMNFYT

KQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGVNPCTETFTGTLQYMAPEIIDQGPRGYGAPADIWSLGCTIIEMATSKPPFHEL
|||||||||||||||||||||||||||||||||||||||||.|||||.|||||||||||||||||.||||.||||.||||||.|||..||||.|||||||
KQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTCKRLAGINPCTETFTGTLQYMAPEVIDQGQRGYGKPADIWSFGCTMVEMATGKPPFHEL

GEPQAAMFKVGMFKIHPEIPEALSAEARAFILSCFEPDPHKRATTAELLREGFL
||||||||||||.|.||||||.||||...|||.||||||.|||....||...||
GEPQAAMFKVGMYKKHPEIPEELSAECKNFILRCFEPDPCKRASAQDLLQDPFL
Kinase MAP3K7.AA STE11 652-908 43 1.1e-161 543.41 In-house 1-303 (303) Show / Hide 
Range on Protein: 652-908
Range on HMM: 1-303/303
Sequence Identity: 43% (131 aa)

NGERVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSR--------YSQP------LHEEIALHKYLKHRNIVQYLG-SVS--ENGYIKIFMEQVPGGSL
  .. ..|||..| ||...........|.|.|......        . |.      ..|||.|.| |.| |||.|.| ...  .|....||||..|||||
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSL

SALLRSKWGP--MKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGVNPCTET----------FTGTLQ--------
|..||.||||  . |..|..|||||||||.|||...|.||||||.|.|......|.|..|||..||||. ..||..          .|||..        
SSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPM

YMAPEIIDQGPRG-YGAPADIWSLGCTIIEMATSKPPFHELGE-PQAAMFKVGMF-KIHPEIPEALS------AEARAFILSCFEPDPHKRATTAELLRE
.||||.|.|..|. ||..|||||||||.||||| |||.|.... ..|||||.||. | ||.||| .|      .|.|.|.. |||.||.||.| ..||. 
WMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQH

GFL
 |.
PFI
Kinase MAP3K7.AA STE 653-908 27 1.1e-104 354.08 In-house 1-359 (359) Show / Hide 
Range on Protein: 653-908
Range on HMM: 1-359/359
Sequence Identity: 27% (102 aa)

GER-VVLGKGTYGIVYAGRDLS---------------NQVRIAIKEIPERDS-----------------RYSQPLHEEIALHKYLK--HRNIVQYLGSVS
 |.  ..|||..| || ...                 .....|||... ...                    | . .|| ..| ..  | |||.|.|.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

ENG-------YIKIFMEQVPGGSLSALLRSKWGPMK-------------EPTIKFYTKQILEG-LKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTS
 .|       .. |.|| ..||||. ....|.|. |             |. |.....|||.| |.|||...|.|||||..|.|.      ||..|||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL------VKLCDFGVC

KRLAGVNP----------------CTETFTGTLQYMAPEIIDQGPRG----YGAPADIWSLGCTIIEMATSKPPF---HELGEPQAAMFKVGMF------
..|.  ..                 . ||.||  .||||.|.|. .|    |.. .|||||||||||||| |||.   | .    ...|. .|.      
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

----KIHPEIPE-------------------ALSAEARAFILSCFEPDPHKRATTAELLR--EGFL
    . .| .|.                    .| | . ||  |.. ||.||.|. .||.    |.
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase MAP3K7.AA STE11-Unclassified 655-908 34 1.2e-93 317.44 In-house 4-308 (308) Show / Hide 
Range on Protein: 655-908
Range on HMM: 4-308/308
Sequence Identity: 34% (108 aa)

RVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSR-----YSQP----LHEEIALHKYLKHRNIVQYLGSV--SENGYIKIFMEQVPGGSLSALLRSKWG
. ..|||..| || . ....   .|.|.| . |.        .     . .|... | | | |||||.|     ... | ||||..||||....|. | |
GEFIGKGSFGQVYKCMNCNTGEFMAVKQIEIHDYNSQQEDMQKEMIQSIQKEMKVLKQLNHKNIVQYYGCEIHKHEDCINIFMEYMPGGSIWSMLN-KYG

PMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLA----------------GVNPC-TE--------TFTGTLQ---Y
.  |..|| |||||||||.|||.. |.||||||.|.|. .  |..|..|||..|  .                 .. | ..        .  ||..   .
CFDEMVIKKYTKQILEGLAYLHSHGIIHRDIKGANILIDF-DGICKLTDFGCAKQIEFDRTRTVRMNKIQNFDHYKICQHINSQQNHCKSMQGTPYQPFW

MAPEIID---QGPRGYGAPADIWSLGCTIIEMATSKPPFHELGE--PQAAMFKVGMFKIHPEIPEALS-----------AEARAFILSCFEPDPHKRATT
||||.|.   |.  |... .||||||||.||||| |.|.  . .  ...|..|..| .  |.||| ||           .|...|.  ||. ||.||.|.
MAPEVIKNSTQT--GHCRKSDIWSLGCTVIEMATGKHPWSNCQNDNFMWAIMKIVMSNQIPQIPEHLSPVCDFISCWISQECKDFLRKCFQIDPKKRPTA

AELLREGFL
 .||   |.
NQLLQHPFI
Kinase MAP3K7.AA S_TKc 652-908 30 1.6e-89 304.63 SMART 1-231 (231) Show / Hide 
Range on Protein: 652-908
Range on HMM: 1-231/231
Sequence Identity: 30% (82 aa)

NGERVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKYLKHRNIVQYLGSVSENGYIKIFMEQVPG--GSLSALLRSKWGP-----
     ..|||..| || .|. . . . |||.|.       . .  ||...|  .| |||.....  . ... ..|| ..|  |.|  ..... ..     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

MKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGVNPCTETFTGTLQYMAPEIIDQGPRGYGA-PADIWSLGCTIIE
. | ...||..||...|.|.|...|.|||.| .|.|...   ..||.||| ...|        || ||. |||||..     |||  ..|.||.||...|
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL-------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILYE

MATSKPPFHELGEPQAAMFKVGMFKIHPEIPEALSAEARAFILSCFEPDPHKRATTAELLR-------EGFL
|.. .|||.     ...|||. .           | ||. ||  |.. || || |  |.|.         ..
MLCGYPPFP----QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase MAP3K7.AA Pkinase 657-908 29 6.3e-80 276.64 Pfam 6-293 (293) Show / Hide 
Range on Protein: 657-908
Range on HMM: 6-293/293
Sequence Identity: 29% (86 aa)

VLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHE----EIALHKYLKHRNIVQYLGSVSENGYIKIFMEQVPGG----SLSALLR-SKWGPM--
..|.|..| || ... ... . |.|.|. |. . ... .     ||...| |.| |||...... ....| . || ..||    .|..... .. |..  
KIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYF

KEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVV----KISDFGTSKRL-AGVNPCTETFTGTLQYMAPEIIDQGPRGYGAPADIWSLGCT
 | ..||| .|||.||.|.|.. |.|||.| .|.|..   |..    ||.||| .| .    |. . ||.||. |||||.|  | ..|| ..|.||.||.
SEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-GGQYYGPKVDMWSCGCI

IIEMATSKPPFHEL-----GEPQAAMFKVGMFKIHPEIPEALS-------------------AEARAFILSCFEPDPHKRATTAELLREGFL
..||.. .||| .       .... ...... ..| ..|.  |                    |.. || .|...||.|| | ...|   ..
LYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase MAP3K7.AA MEKK15 651-908 42 3e-72 246.32 In-house 2-264 (264) Show / Hide 
Range on Protein: 651-908
Range on HMM: 2-264/264
Sequence Identity: 42% (116 aa)

ANGERVVLGKGTYGIVYAGRDLSNQVRIAIKEIP------ERDSRYSQPLHEEIALHKYLKHRNIVQYLGSVSENGYIKIFMEQVPGGSLSALLRSKWGP
  |.  .|||| || || |     |. ||.| .       |.  .  . | ||. | | |||.||| |||   |.  . |||. |||||.|...  ..||
KKGN--ILGKGAYGTVYCGLTNTGQL-IAVKQVELDEIDKEKAKQQYRKLQEEVDLLKTLKHKNIVAYLGVCLEDNVVNIFMQFVPGGSISSII-NRFGP

MKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLA--GVNPCT----ETFTGTLQYMAPEIIDQGPRGYGAPADIWSLG
. |     ||||||.| .||||| .||||||| ||..    |..|. |||  |||.  |.|           ||  .||||.|     |||  .||||.|
LDEMVFCKYTKQILQGVQYLHENCVVHRDIKGNNVMLMP-TGIIKLIDFGCAKRLCWQGINRTHSDMLKSMRGTPYWMAPEVIME--TGYGRKSDIWSIG

CTIIEMATSKPPFHELGEPQAAMFKVGMF-KIHPEIPEALSAEARAFILSCFEPDPHKRATTAELLREGFL
||. |||| |||. .. .. |||| .|    . |..|.  | .|| |.  |   | | |.|  .||.  |.
CTVFEMATRKPPWADM-DRMAAMFYIGAHRDPMPQLPVKFSEDARMFVRMCLTRDQHERPTASQLLKHPFI
Kinase MAP3K7.AA MEKK2 654-908 40 3.2e-65 222.97 In-house 3-262 (262) Show / Hide 
Range on Protein: 654-908
Range on HMM: 3-262/262
Sequence Identity: 40% (108 aa)

ERVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERD-----SRYSQPLHEEIALHKYLKHRNIVQYLGSVSENG--YIKIFMEQVPGGSLSALLRSKWGPMK
   .||.| .| ||   |      .|.| ..  .     ..  | |. || | | |.|  |||| | . .|.   . |||| .||||.   |.  .|.. 
RGKLLGQGAFGRVYVCYDVDTGRELAVKQVQFDPDNPETRKEVQALECEIQLLKNLQHERIVQYYGCLRDNQEKTLSIFMEYMPGGSVKDQLKA-YGALT

EPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGVNPCT---ETFTGTLQYMAPEIIDQGPRGYGAPADIWSLGCTIIE
|   . ||.|||||..|||.. |||||||| |.| .  || ||..||| ||||  .        . |||  .|.||.|.    |||  ||.||.|||..|
ETVTRKYTRQILEGMHYLHDHMIVHRDIKGANILRDS-SGNVKLGDFGASKRLQTICMHITGMKSVTGTPYWMSPEVING--EGYGRKADVWSIGCTVVE

MATSKPPFHELGEPQAAMFKVGMFKIHPEIPEALSAEARAFILSCFEPDPHKRATTAELLREGFL
| | |||. |  |  ||.||.   .  |..|. .| .|| |.  ||      |   .||||  | 
MLTEKPPWAEY-EAMAAIFKIATQPTNPQLPQHVSQHARDFLKRCFVEIKQDRPSAEELLRHHFV
Kinase MAP3K7.AA CAMK 657-908 17 2.7e-63 202.54 In-house 1-425 (425) Show / Hide 
Range on Protein: 657-908
Range on HMM: 1-425/425
Sequence Identity: 17% (73 aa)

VLGKGTYGIVYAGRDLSNQ------------VRIAIKEIP-----------------ERDSRYS-----------QPLHEEIALHKY-------LKHRNI
.||.|..|.|. ... ...            .. ||| |.                  ..|. .           . .  ||...|        |.|.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQYLGSVSENGY-------------------IKIFM---EQVPGG----SLSALLRSK--------------WGPMKEPTIKFYTKQILEGLKYLHENQI
.. .     . |                   . ..|   | ..||     |   ....              .| ..|   ..| .||.....|.|.. |
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDIKGDNVLVNTYS----------------GVVKISDFGTSKRLAGV-----------------------NPCTETFTGTLQYMA-PEIIDQGP----
||||.| .|.|... .                . .||.||| .... .                        ..  .|| ||. ||| ||.. . .    
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------RGYGAPADIWSLGCTIIEMATSKPPFHELGEPQAA--------------MFKVGMFK-IHPEIPE-------------------ALSAEARA
        ..|| ..|.||.|.    | . .||| .  . .                . . | .  ..|....                    .|.|.. 
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

FILSCFEPDPHKRATTAELLREGFL
.| .. ..|| ||.| .. |.  ..
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase MAP3K7.AA STE20 657-908 34 4.7e-62 212.48 In-house 6-288 (288) Show / Hide 
Range on Protein: 657-908
Range on HMM: 6-288/288
Sequence Identity: 34% (98 aa)

VLGKGTYGIVYAGRDLSNQVR----IAIKEIPERDS----RYSQPLHEEIALHKYLKHRNIVQYLGSVSEN----GYIKIFMEQVPGGSLSALLRS--KW
..|.|.|| || ... ...      .||| .. ..        . .  ||   | .|| |||.|.||   .      . | ||   ||||. ...   |.
KIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMKHCMKC

G------PMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAG-----VNPCTETFTGTLQYMAPEIIDQGP---RGY
|      ||.|. | . ....|.||.|||.|.|.|||||.||.|... .| ||..||| .  |        ..   || ||  .||||.| .      ||
GKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTE-DGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGPDKGY

GAPADIWSLGCTIIEMATSKPPFHELGEPQAAMFKVGMFKIHP---EI--PEALSAEARAFILSCFEPDPHKRATTAELLREGFL
.  .|||||| |.||||. .||....  |  |||..   .  |   .   |.  | | . |. .| . ||.||.|. .||.  |.
DYKCDIWSLGITAIEMAEGEPPYFDM-HPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase MAP3K7.AA Ciliate-E2 657-908 21 7.6e-54 183.21 In-house 6-365 (365) Show / Hide 
Range on Protein: 657-908
Range on HMM: 6-365/365
Sequence Identity: 21% (79 aa)

VLGKGTYGIVYAGRDLSNQVR-----------------------IAIKEIPERDSRYSQP-LHEEIALH------------KYLKHRNIVQYLGSVS--E
..|.|..|.|| ... ..| .                       .|.| . ... ..    .|.   ..            . |.| ||...  .     
KIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKD

NGYIKIFMEQVPGGSLSALLRSKW----------GPMKEPTIKFYTKQILE---------------GLKYLHENQ-IVHRDIKGDNVLVNTYSGVVKISD
. .| . || . ||.|  ......          ....|  ||...||||.               .|.|||..  |.||||| .|.|.      .||.|
DNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------IKIID

FGTSKRLAGVNP-------------------------------CTETFTGTLQYMAPEIIDQGP-------RGYGAPADIWSLGCTIIEMATSKPPFHEL
||.||..   |                                 . |. ||. ||||||.  ..        ||.  .||||||... || . ||||   
FGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF---

GEPQAAMFKVGMFKIHPE--------------IPEALSAEARAFILS----CFEPDPHKRAT-TAELLREGFL
        | . ... ..              ... .| |.  .|      ... || || |   ..|   ..
----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase MAP3K7.AA STE-Unique 724-908 27 8.3e-48 165.15 In-house 371-616 (616) Show / Hide 
Range on Protein: 724-908
Range on HMM: 371-616/616
Sequence Identity: 27% (68 aa)

IFMEQVPGGSLSALLRSKWGP--------MKEPTIKFYTKQILEGLKYLHENQ--IVHRDIKGDNVLVNTYS----GVVKISDFGTSKRLAGV-------
||||  ..|.|. .. .  .|        . |  .. ||.|||||| |||  .  |.|||.| .|.. .         |||.|||...... .       
IFMEYCEHGTLQQIIKRCGCPGNPNNLQLFPETEVIWYTYQILEGLEYLHSQHNPIIHRDLKPHNIFCMQDGKGRVCKVKICDFGHATCCQPDHFEKDNN

-------------------------------NPCTETFTGTLQYMAPEII---DQGPRGYGAPADIWSLGCTIIEMATSKPPFHELGEPQA-AMFKVGMF
                               |    .  ||  ||.||.|   .|.  .|.. .|||||||....|..  ||.|...  || .       
SKNSNTWININNNSSTNSTAQQTPMWDLNINNYTMKYCCGTPCYMCPEVINCRNQINNPYDTKVDIWSLGCMCFHMCCGCPPWHQRYHMQAYIEMCIHIH

KIHP-----EIPEALSAEARAFILSCFEPDPHKRATTAELLREGFL
.. |     .||. .. | . || .|.|..||.|.....||. ..|
CQPPQCPIENIPPKCQPEQQQFIEKCLERNPHHRPSAHQLLHHFWL
Kinase MAP3K7.AA Pkinase_Tyr 657-794 29 1.5e-22 76.96 Pfam 6-156 (270) Show / Hide 
Range on Protein: 657-794
Range on HMM: 6-156/270
Sequence Identity: 29% (45 aa)

VLGKGTYGIVYAGRDL----SNQVRIAIKEI-PERDSRY--SQPLHEEIALHKYL-KHRNIVQYLGSVS-ENGY--IKIFMEQVPGGSLSALLRSK---W
.||.| .| || |.      ....  |.| . .  ...   .. . .|... | | .| |||...| .. . .   | | || .|.|.|   ||..    
KLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDK

GPMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFG
.| . ...  .  || .|. ||......|||.   |.||.  ..||||.|||
QPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE-NNVVKICDFG
Kinase MAP3K7.AA TyrKc 657-907 24 6.9e-17 50.37 SMART 6-280 (280) Show / Hide 
Range on Protein: 657-907
Range on HMM: 6-280/280
Sequence Identity: 24% (71 aa)

VLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKYL--KHRNIVQYLGSVSEN-------GYIKIFMEQVPGGSLSALLRSKWGPMKE
.|| | .|.|| |.     .  |.| . |      . ...|. . . |  .| |||. .| ...        . . | || .|.|.|   ||.. .  . 
KLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCM

PTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGV---------NPC----TETFTGTLQYMAPEIIDQGPRG-YGAPAD
..   .  || .|  |||.....|||.   |.||.    .||||||| |. .                    . .   .  |||| |     | .    |
KDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---NYGKFTTKSD

IWSLGCTIIEMATS-KPPFHEL----GEPQAAMFKVGMFKIHPEIPEA-------LSAEARAFILSCFEPDPHKRATTAELLREGF
.|| | .. |. |  ..|  .      ..| .. .|   .  |  |..        ..|    ...| . ||..| | .|. .| |
VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase MAP3K7.AA STE-Unique 653-720 27 5.1e-11 34.81 In-house 1-74 (616) Show / Hide 
Range on Protein: 653-720
Range on HMM: 1-74/616
Sequence Identity: 27% (20 aa)

GERVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYS------QPLHEEIALHKYLKHRNIVQYLGSVSENG
 . . .|.|  | |.  .. ..  | ||| |...  . .      ... .|| ..|.|.| ||| |.|.. ..|
NCQQMIGRGSFGNVHNCQNKKDCFRCAIKVIHLKQFKDFNQEPLVNMIISEIEIMKCLHHQNIVKYYGHWLWGG
Sam7 MAP3K7.AA sam7 1239-1301 24 1.3e-11 39.13 In-house 1-70 (70) Show / Hide 
Range on Protein: 1239-1301
Range on HMM: 1-70/70
Sequence Identity: 24% (17 aa)

RTDKELIDWLRLQGA--DAKTIEKIVEEGY----TLSDILNEITKEDLRYLRL-RGGLLCRLWSAVSQYR
 |.... .||.  |   . . .... ..|.    |  | | ..|.|||. .   |.|  ...|... | |
WTFEDVCEWLEWIGMENFQQYCDNFRDHGIDDWVTDGDHLCHMTEEDLMEMGITRPGHRKKIWNHIQQMR