Gene MOS (Human)

MOS

Species: Human
Alias: MOS, MSV, c-mos, MGC119963, MGC119962
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 8q11.2,

Classification

Group: Other
Family: MOS

Sequence

Name Sequence Type Origin Length Description Download
MOS.NA RNA Sugen Kinome 1302 None Fasta, JSON
MOS.AA Protein Sugen Kinome 346 None Fasta, JSON
MOS.kin_dom Protein Kinase Domain Sugen Kinome 281 None Fasta, JSON

Protein domain

Protein domains of MOS.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MOS.AA MOS 60-340 53 3.1e-203 679.98 In-house 1-299 (299) Show / Hide 
Range on Protein: 60-340
Range on HMM: 1-299/299
Sequence Identity: 53% (163 aa)

VCLLQRLGAGGFGSVYKATYRGVPVAIKQVNKCTKNRLASRRSFWAELNVARLRHDNIVRVVAASTRTPAGSNSLGTIIMEFGGNVTLHQVIYGAAGHPE
|||.|..|.||||||.||.|.|.|||.|||||||||. |.|||||||.|..||||||||||.|.|.|.|...|.|||||||.|||.|||||||....||.
VCLCQMIGRGGFGSVWKAQYCGRPVAVKQVNKCTKNLKAMRRSFWAEVNYLRLRHDNIVRVMAVSQRSPEDFNNLGTIIMECGGNQTLHQVIYEPTRHPP

GDAGEPHCRTGGQLSLGKCLKYSLDVVNGLLFLHSQSIVHLDLKPANILISE-----------------QDVCKISDFGCSEKLED----LLCFQTPSYP
||||..|||   .|.|..|.||||||||.|...|.|.|.|||.|||||...|                 |||||..|||||....|    ..|..|....
GDAGIIHCR---MLILMHCCKYSLDVVNALQYCHHQNILHLDVKPANIIVDEGTKSSITCNSSKIKVKRQDVCKLCDFGCSQQMFDSNGKEFCAWTNPHY

LGGTYTHRAPELLKGEGVTPKADIYSFAITLWQMTTKQAPYSGERQHILYAVVAYDLRPSLSAAVFEDSLPGQRLGDVIQRCWRPSAAQRPSARLLLVDL
|.||.|..|||||.|...|||||||||.||.|||.|...||.||..|..||...|..|......|.|.|.........||.||.....||||||.|...|
LKGTCTYMAPELLCGDTPTPKADIYSFGITMWQMQTRETPYHGEDCHHVYAYQVYKHRMRPDNPVYENSCENDWYRQLIQKCWPKQPEQRPSARQLKHEL

TS
..
EM
Kinase MOS.AA Pkinase 60-338 22 1.6e-69 242.07 Pfam 1-293 (293) Show / Hide 
Range on Protein: 60-338
Range on HMM: 1-293/293
Sequence Identity: 22% (71 aa)

VCLLQRLGAGGFGSVYKATYRGVP--VAIKQVNKCTKNRLASRRSFW-AELNV-ARLRHDNIVRVVAASTRTPAGSNSLGTIIMEFGGNV----TLHQVI
 ......|.|.||.|||.. .| .  ||.|...|....    .. .. .|. . .||.|.||||   . ..   ...    ..||. ..      |. .|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED---KDHIY--MVMEYCEGGLYVMDLFDYI

YGAAGHPEGDAGEPHCRTGGQL--SLGKCLKYSLDVVNGLLFLHSQSIVHLDLKPANILISEQDVC----KISDFGCSEKLEDLLCFQTPSYPLGGTYTH
 .              . .| .  |   | .| . .. || ..||..|.| ||||.||||......    ||.|||......  .  ..  . . ||.  
ST--------------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWY

RAPELLK-GEGVTPKADIYSFAITLWQMTTKQAPYSGE----RQHILYAVVAYDLRPSLSAAVFEDSLPG-----------------QRLGDVIQRCWRP
.|||... |.. .||.|..|. ..|..| ... |..|.    . |  ..... ...| |.   .... .                  . . |.| .|...
MAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCK

SAAQRPSARLLLVD--L
  ..||.|. .| .  .
DPKKRPTAEQILQHPWF
Kinase MOS.AA TKL 66-338 20 8.5e-52 178.4 In-house 1-364 (364) Show / Hide 
Range on Protein: 66-338
Range on HMM: 1-364/364
Sequence Identity: 20% (80 aa)

LGAGGFGSVYKATYRG----------VPVAIKQVNKCT-------------------------KNRLASRRSFWAELNVARLRHDNIVRVVAASTRTPA-
.| |||| |||...||           .||.|. ..                           ... .  .     .   ||||.|||. ...... |  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-------GSNSLGTIIMEFGGNVT-LHQVIYGAAGHPEGDAGEPHCRTGGQLSLGKCLKYSLDVVNGLLFLHSQS--------IVHLDLKPANILISEQD
       |. .   |.||.  . . ||...                       . . .. .||.  |. .|||.         |.| |||..|||. |  
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENW

V--------------CKISDFGCSEKLEDLLCFQTPSYP----------------LGGTYTHRAPELLKGE----------------GVTPKADIYSFAI
               |||.||| |  ..     .  ..                  .||. . |||.|.|.                  ..|.|.|||.|
TNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGI

TLWQMTTKQAPYS--GERQHILY-------AVVAY-DLRPSLSAAVFE------DSLPGQRLGDVIQRCWRPSAAQRPSARLLLVDL
 || . | . ||.  .....|.        ..|..  ||| .     .       .   ... . .|.|| . . .|||.  .|  |
VLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase MOS.AA MLK 60-338 24 1.5e-39 134.91 In-house 1-291 (291) Show / Hide 
Range on Protein: 60-338
Range on HMM: 1-291/291
Sequence Identity: 24% (75 aa)

VCLLQRLGAGGFGSVYKATYRGVP-----VAIKQVNKCTKNRLAS----RRSFWAELN-VARLRHDN----IVRVVAASTRTPAGSNSLGTIIMEFGGNV
  ... .|.|.||.|.|...|.       ||.|.|.  .    ..    .. |  | . ...|.| |    |..........| .      |.||.  . 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHF----CIVMEYCEGG

TLHQVIYGAAGHPEGDAGEPHCRTGGQLSLGKCLKYSLDVVNGLLFLHSQS---IVHLDLKPANILISE------QDVCKISDFGCSEKLEDL----LCF
 |. |..|| ..... .  .     .  ...  .. .|.. .|. .|||.    |.| |||. ||||.|      ....||.||| | .. .      ..
SLYNVLHGARSKWMDAN-HNQK-NDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSN

QTPSYPLGGTYTHRAPELL---KGEGVTPKADIYSFAITLWQMTTKQAPYS--GERQHILYAVVAYDLRPSLSAAVFEDSLPGQRLGDVIQRCWRPSAAQ
.       |||  .||| .   ..| .. |.|..|... ||.| |.. ||.   .   |.. |..  ||| .     . . |  ..   ...|| . ...
A-------GTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPI-----PSTCP-EHWKKLMKQCWNQDPHK

RPSARLLLVDL
||| |  .  |
RPSFRQIVQHL
Kinase MOS.AA S_TKc 60-339 20 1.7e-35 125.17 SMART 1-231 (231) Show / Hide 
Range on Protein: 60-339
Range on HMM: 1-231/231
Sequence Identity: 20% (62 aa)

VCLLQRLGAGGFGSVYKATYRG--VPVAIKQVNKCTKNRLASRRSFWAELNVARLRHDNIVRVVAASTRTPAGSNSLGTIIMEFGGN--VTLHQVIYGAA
  .|. .| |.||.|||.. ..    ||||...          .... |... . .|.|||.   .         .   ..||. ..   .|...|    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKKHHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYI----

GHPEGDAGEPHCRTGGQ-----LSLGKCLKYSLDVVNGLLFLHSQSIVHLDLKPANILISEQDVCKISDFGCSEKLEDLLCFQTPSYPLGGTYTHRAPEL
           .. |..     ..   . .|   ....| ..||. |.| ||||.|||..|  . ||.||| . .|          . . ||   .|||.
-----------KKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEV

LKGEGVTP-KADIYSFAITLWQMTTKQAPYSGERQHILYAVVAYDLRPSLSAAVFEDSLPGQRLGDVIQRCWRPSAAQRPSARLLLV--------DLT
|   | .. |.|..|. ..|. | . . |..   .. .. ..                   . . | |..|..   ..||.|  .|            
L---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase MOS.AA TK 60-338 16 6.3e-34 110.54 In-house 1-486 (486) Show / Hide 
Range on Protein: 60-338
Range on HMM: 1-486/486
Sequence Identity: 16% (81 aa)

VCLLQRLGAGGFG---SVYKATYRG---------------------------VPVAIKQVNKCTKNRLASRRS--------------FWAELNVAR---L
. |.. ||.| ||    |||...||                           .|||.|.. . . .  . ..               ...|. . .   .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHDNIVRVVAASTRTPAGS-------NSLGTIIMEFGGNVT----LHQVIYGAAGHPEGDAGEPH----------------------------CRTGGQ-
.|.|||| ....|.    .       .    |.||.  .      |..      ..    . .|.                            | . .| 
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPC-PEEQD

--------------------------------LSLGKCLKYSLDVVNGLLFLHSQ------SIVHLDLKPANILISEQDV-----------CKISDFGCS
                                |..   | ..... .|. .|||.       .|| ||   |.|..|..|           |||.||| |
YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

EKLEDL-LCFQTPS----YPLGGTYTHR---------------------------APELLKGEG---------VTPKADIYSFAITLWQMTTKQ-APYSG
 . . . |.   .|    |  .. .| |                           ||| |..            |.| |..|| ...| . |   .|| |
RQGS-GVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYG

ERQH------------ILYAVV------------AYDLRPSLSAAVFE--------DSLPGQRLGDVIQRCWRPSAAQRPSARLLLVDL
.  .            . | .              | .|.   .   .         . | . . |..|.||.. ...||. . |.  |
GMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase MOS.AA RIPK 185-330 28 1.1e-25 84.55 In-house 116-282 (290) Show / Hide 
Range on Protein: 185-330
Range on HMM: 116-282/290
Sequence Identity: 28% (48 aa)

VVNGLLFLHSQS--IVHLDLKPANILISEQDVCKISDFGCSEKLEDLLCFQ----------TPSYPLGGTYTHRAPELLK---GEG---VTPKADIYSFA
.. |  .|||.   | |.||||.|||.      ||.||| .  ..    .|          . | . .||  . .||..          |||| |.||||
ISCGMCYLHSMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNKKPIKVVTPKYDVYSFA

ITLWQMTTKQAPYSG-ERQHILYAVVAYDLRPSLSAAVFEDSLPG----QRLGDVIQRCWRPSAAQRPS
|..|.  |.  ||.. .   .. .... . ||.|.     .. |     ... ...||||.  . .||.
IVMWEVLTQKHPYEDRKCMMMIMMCCKQGHRPCLQPVP--EYWPEPPHCEQMIELMQRCWQQDPNDRPC
Kinase MOS.AA Dicty4 172-330 29 6.3e-25 80.22 In-house 105-265 (277) Show / Hide 
Range on Protein: 172-330
Range on HMM: 105-265/277
Sequence Identity: 29% (50 aa)

QLSLGKCLK---YSLDVVNGLLFLHS--QSIVHLDLKPANILISEQDVCKISDFGCSE---KLEDLLC-FQTPSYPLGGTYTHRAPELLKGEGVTPKADI
.|...  ..   . .|.. |.  ||.    |.|.|||..|.|...  . |..||| |    | ||.     |.     ||    ||| . ... . ||| 
KLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTAC----GTPCWMAPEVMMHQPYNEKADV

YSFAITLWQMTTKQAPYS--GERQHILYAVVAY-DLRPSLSAAVFEDSLPGQRLGDVIQRCWRPSAAQRPS
|||.| ||.. |.|.||.  .    .... |.   |||.... .        .. . ||.|| ..  .|||
YSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWC------PPSWKHLIQWCWDHDPQHRPS
Kinase MOS.AA TKL-Unique 62-221 28 7.3e-23 77.58 In-house 1-162 (290) Show / Hide 
Range on Protein: 62-221
Range on HMM: 1-162/290
Sequence Identity: 28% (49 aa)

LLQRLGAGGFGSVYKATYRGVPVAIKQVNKCTKNRLASRRSFWAELNV-ARLR-HDNIVRVVAAST-RTPAGSNSLGTIIMEFGGNVTLHQVIYGAAGH-
 .  .|.||.|.|||...|| |||||| ..  . .. ... |  |.|.  .|. |.|||. .....  ... .|.   |.||.    .|. |.     | 
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMC--IVMEYCPGGSLYDVL-----HQ

--PEGDAGEPHCRTGGQLSLGKCLKYSLDVVNGLLFLHSQS--IVHLDLKPANILISEQ-----DVCKISDFG
  .     ...|     |.. . .|  .|.. |. .||. .  | |.|||. |.|...         ||.|||
NNNNNNNNNNNC----KLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFG
Kinase MOS.AA STE 180-280 26 3.6e-22 75.15 In-house 155-269 (359) Show / Hide 
Range on Protein: 180-280
Range on HMM: 155-269/359
Sequence Identity: 26% (34 aa)

KYSLDVVNG-LLFLHSQSIVHLDLKPANILISEQDVCKISDFGCSEKLEDL---------------------LCFQTPSYPLGGTYTHRAPELLKG----
..  ... | | .|||. |.| |.||||||.     .|..|||.. .|.|                       .  ||         . ||| ...    
YICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP---------WMAPEVIQQNGQG

--EGVTPKADIYSFAITLWQMTTKQAPYS
   | . |.||.|. .|.. | | . |..
RDKGYDTKCDIWSLGCTIIEMATGKPPWH
Kinase MOS.AA Pkinase_Tyr 60-221 25 1.7e-20 70.04 Pfam 1-156 (270) Show / Hide 
Range on Protein: 60-221
Range on HMM: 1-156/270
Sequence Identity: 25% (44 aa)

VCLLQRLGAGGFGSVYKATYR------GVPVAIKQVNKCTKNR-LASRRSFWAELNV-ARL-RHDNIVRVVAAST-RTPAGSNSLGTIIMEFGGNVTLHQ
. ... ||.| ||.|||.|..      ..|||.| ..  .  . .  |..| .|...   | .|.|||| ... | .   .      |.||.  .  |. 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQN-CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN---QIYIVMEYMPHGDLLD

VIYGAAGHPEGDAGEPHCRTGGQLSLGKCLKYSLDVVNGLLFLHSQSIVHLDLKPANILISEQDVCKISDFG
                    ...|..   |...... .|. .|.|. ..| ||   |.|..|. |.||.|||
YLRKHR------------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase MOS.AA ULK 169-281 23 3.8e-20 68.23 In-house 119-254 (324) Show / Hide 
Range on Protein: 169-281
Range on HMM: 119-254/324
Sequence Identity: 23% (32 aa)

TGGQLSLGKCLKYSLDVVNGLLFLHSQSIVHLDLKPANILISEQD------------VCKISDFGCSEKLED--LLCFQTPSYP----LGGTYTHRAPEL
... ||  .....  . .||. .||.. |.| |.||.||||.. .            |.||.||| . ....  .  ... ..     . ||    ||..
EKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQI

LK----GEGVT-PKADIYSFAITLWQMTTKQAPYSG
|.    ..  .  |.||.|. . . .| . . |...
LQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFS
Kinase MOS.AA LRRK 179-340 27 3.3e-19 64.58 In-house 167-351 (351) Show / Hide 
Range on Protein: 179-340
Range on HMM: 167-351/351
Sequence Identity: 27% (52 aa)

LKYSLDVVNGLLFLHSQS--IVHLDLKPANILI--SEQD----------VCKISDFGCSEKLEDLLCFQTP-SYPLGGTYTHRAPELLKGE---GVTPKA
|| .|..  |. .|||..  |.| |||. |||.  | |.          ..||.||| |  .    ||..     ..|. . .||| ....     | |.
LKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISR-MF--QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKV

DIYSFAITLWQMTTKQ-APYSGER-------QHILYAVVAYDLRPSLSAAVFEDS-LPGQRLGDVIQRCWRPSAAQRPSARLLLVDLTS
|.|||.. ||   | |  |. .         . ..   .   |||...   ..   .|. .. | || ||     .||..   .  | .
DCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQH-YCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase MOS.AA TyrKc 60-338 23 2.1e-17 58.72 SMART 1-280 (280) Show / Hide 
Range on Protein: 60-338
Range on HMM: 1-280/280
Sequence Identity: 23% (71 aa)

VCLLQRLGAGGFGSVYKATYRGVPVAIKQVNKCTKNRLASRRSFWAELNV-ARL--RHDNIVRVVAASTRTPAGSN----SLGTIIMEFGGNVTLHQVIY
. |.. || | || |||.|.. ..||.| .....      |. |  |...  .|  .|.|||| ... |    | |        |.||.  .  |.. . 
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQ--GRNFMYIEPLMIVMEYMPHGDLKDYLR

GAAGHPEGDAGEPHCRTGGQLSLGKCLKYSLDVVNGLLFLHSQSIVHLDLKPANILISEQDVCKISDFGCSEKLEDL---LCFQTPSYPLGGTYTHR---
   ..               |.. . |...... .|  .|||. ..| ||   |.|..|. ..|||||| | ...|        .  |   ..   .   
KHRPK---------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-ESKDYYRKKEHKGGKTML

-----APELLKGEGVTPKADIYSFAITLWQMTTK-QAPYSG------ERQHILYAVVAYDLRPSLSAAVFEDSL----PGQRLGDVIQRCWRPSAAQRPS
     ||| ..    |.| |..|| ...| . |  | ||.|      . |...  | . . .|    .     .      . . .....||.  ...||.
PIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY--P-MSFVCCPDEMYQIMKQCWHEDPEDRPT

ARLLLVDL
 . .  ..
FSEIHECF
Kinase MOS.AA TKL-Unique 241-330 31 7.7e-12 38.2 In-house 188-282 (290) Show / Hide 
Range on Protein: 241-330
Range on HMM: 188-282/290
Sequence Identity: 31% (32 aa)

GTYTHRAPELLKG--EGVTPKADIYSFAITLWQMTTKQA------PYSGERQHILYAVVAY---DLRPSLSAAVFEDSLPGQRLGDVIQRCWRPSAAQRP
|..  .|||.|..  .  . |.|.|||.| || . | .       ||.|  |  ....|.|    .|| ..     ...| ... | ||.||..   |||
GSFRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIP-----NHCP-KEYRDLIQQCWHHDPSQRP

S
|
S
Kinase MOS.AA Dicty4 60-87 53 2.9e-08 23.83 In-house 1-28 (277) Show / Hide 
Range on Protein: 60-87
Range on HMM: 1-28/277
Sequence Identity: 53% (15 aa)

VCLLQRLGAGGFGSVYKATYRGVPVAIK
    ||.| |.||.|||.| ||  ||.|
INIEQRIGKGSFGEVYKGTWRGKEVAVK
Kinase MOS.AA STE 60-119 21 2.7e-07 21.95 In-house 1-94 (359) Show / Hide 
Range on Protein: 60-119
Range on HMM: 1-94/359
Sequence Identity: 21% (20 aa)

VCLLQRLGAGGFGSVYKATYR-----------------GVPVAIKQVNKCTKNR--------------LASRRSFWAEL-NVARLR--HDNIVR
  .....| |.||.|||| ..                 |. .||||.|....|                  . ..  |.    ...  |.|||.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVK
Kinase MOS.AA LRRK 60-92 24 4.9e-07 20.93 In-house 1-62 (351) Show / Hide 
Range on Protein: 60-92
Range on HMM: 1-62/351
Sequence Identity: 24% (15 aa)

VCLLQRLGAGGFG-SVYKATYRG----------------------------VPVAIKQVNKC
.   . .| |||| .||.|..||                             .||||. |..
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRD
Kinase MOS.AA ULK 60-119 26 9.3e-07 20.07 In-house 1-79 (324) Show / Hide 
Range on Protein: 60-119
Range on HMM: 1-79/324
Sequence Identity: 26% (21 aa)

VCLLQRLGAGGFG-SVYKAT-YR----GVPVAIKQVNKCTKNRLASRR-------SFWAELNVAR-LR---HDN--IVR
 || ..|| | ||  |||..  .    .. ||.|...|.  |   ...       ..  | .. . |    | |  ||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVK
Kinase MOS.AA RIPK 66-120 29 2.7e-05 13.97 In-house 1-61 (290) Show / Hide 
Range on Protein: 66-120
Range on HMM: 1-61/290
Sequence Identity: 29% (18 aa)

LGAGGFGSVYKATYR--GVPVAIKQVN--KCTKN--RLASRRSFWAELNVARLRHDNIVRV
.| |||| |.||. |  |. ||.| ..  .| .   .  .   ...   ...||...||..
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPI
Kinase MOS.AA Pkinase_Tyr 315-338 25 0.004445 11.05 Pfam 247-270 (270) Show / Hide 
Range on Protein: 315-338
Range on HMM: 247-270/270
Sequence Identity: 25% (6 aa)

DVIQRCWRPSAAQRPSARLLLVDL
|....||.. ...||. . .. .|
DLMKQCWHYDPEDRPTFSEIHEQL
Kinase MOS.AA Pkinase_Tyr 247-270 37 0.369047 4.55 Pfam 182-205 (270) Show / Hide 
Range on Protein: 247-270
Range on HMM: 182-205/270
Sequence Identity: 37% (9 aa)

APELLKGEGVTPKADIYSFAITLW
||| ..    | | |..|| ...|
APECINYGKFTTKSDVWSFGVLMW