Gene Obscn (Human)
Obscn
Species: Human
Alias: Obscn, OBSCN, UNC89, MGC120410, KIAA1556, MGC120412, MGC138590, MGC120411, FLJ14124, KIAA1639, DKFZp666E245, MGC120409
Annotation:
Consensus chromosomal location: 1q42.13,
Secondary Group: CAMK,
Secondary Family: Trio,
Sequence
Protein domains of Obscn.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| I-set | Obscn.AA | I-set | 10-99 | 41 | 5e-38 | 131.56 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 10-99 Range on HMM: 1-92/92 Sequence Identity: 41% (38 aa) PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAA-GARFRLAQDG-DLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQV |.|...|| ..|..|..|...||. |.|.||||| || ||.. . |.. .|| . |.|||.. .|.|.| |.|.| ||| . . |.| PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| IGc2 | Obscn.AA | IGc2 | 22-89 | 35 | 1.7e-14 | 55.41 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 22-89 Range on HMM: 1-56/56 Sequence Identity: 35% (24 aa) SVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIG | ..|| | |||.|...| | ||.. . .||| . ...||| |.|.|||..| HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| IG | Obscn.AA | IG | 16-100 | 22 | 2.3e-11 | 45.0 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 16-100 Range on HMM: 1-58/58 Sequence Identity: 22% (20 aa) PKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDS---GQYVCRARNAIGEAFA--AVGLQVD |. .|..| ..||.| . |..| ||| .. . || | |.|.|. |.... . |.| PP-VTVKEGETVTLTC-VS-----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ |
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| V-set | Obscn.AA | V-set | 10-99 | 17 | 5e-06 | 22.7 | Pfam | 1-128 (128) | Show / Hide |
Range on Protein: 10-99 Range on HMM: 1-128/128 Sequence Identity: 17% (23 aa) PRFLTR--PK----AFVVSVGKDATLSCQIVGNP----TP-QVSWEKDQQPV--------------AAG-----------ARFRLAQDGD--LYRLTILD . ..| |. .|..|...||.|. .. .. ...| .. || .. |........ . ||| . QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQ-QPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISN LALGDSGQYVCRARNA-IGEAFAAVGLQV | . ||| | | . | .. . . |.| LQPSDSGTYYCAVWNCNEDYFGHGTRLTV |
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| IGv | Obscn.AA | IGv | 26-84 | 19 | 0.006395 | 0.2 | SMART | 1-76 (76) | Show / Hide |
Range on Protein: 26-84 Range on HMM: 1-76/76 Sequence Identity: 19% (15 aa) DATLSCQIVGNPTPQVSWEKDQQ-----------PVAAGARFRLAQDGDL--------YRLTILDLALGDSGQYVCRA ..||||. |. . ...| . . . . . |. .| ||. .| |.| | | SVTLSCKFSGFTF-YMHWYRQPPDSTPKGKGLEWMGY-SYKGRFTWSKDNITRWSKNQFYLTMSNLRPEDTGTYYCAR |
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| I-set | Obscn.AA | I-set | 110-201 | 38 | 3.4e-29 | 101.59 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 110-201 Range on HMM: 1-92/92 Sequence Identity: 38% (36 aa) PHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELG-EASALRIRAARPRDGGTYEVRAENPLGAASAAAALVV |.|. .|... |.||. |.| |.| |.| | ||| |||. | . |. |... . | . |.|. . |.| |.|...|.|..| |.. | | | PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRP-DSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| IG | Obscn.AA | IG | 116-202 | 20 | 1.9e-11 | 45.31 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 116-202 Range on HMM: 1-58/58 Sequence Identity: 20% (19 aa) PTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDG---GTYEVRAENPLGAASA--AAALVVD | . |.||. .|..| | ..|. |.| ..| | ||| .|. | ... . | | PP-VTVKEGETVTLTC-VS-----QIWWY------------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ |
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| IGc2 | Obscn.AA | IGc2 | 122-191 | 30 | 9.9e-11 | 42.9 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 122-191 Range on HMM: 1-56/56 Sequence Identity: 30% (21 aa) REGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLG .|| .|..|.. |.| | ..| | | .| . |.|. ..| | |.|. .|.|| | HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-------------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| V-set | Obscn.AA | V-set | 103-189 | 16 | 0.004312 | 12.49 | Pfam | 1-115 (128) | Show / Hide |
Range on Protein: 103-189 Range on HMM: 1-115/128 Sequence Identity: 16% (20 aa) AACAEQ-APHFLLRPTSIRVREGSEATFRCRVGGSP----RP-AVSWSKDGRRL---------------------GEPDGPRVRVEELGEAS----ALRI . .| |..... ...| || .|..| . .. .. ..|... ... . .. . ||. | | |.| QSQVTQHPPRGCPW--WVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQ-QPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTI RAARPRDGGTYEVRAENP . ..| | ||| . |. SNLQPSDSGTYYCAVWNC |
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| I-set | Obscn.AA | I-set | 248-328 | 36 | 1.7e-23 | 82.24 | Pfam | 11-92 (92) | Show / Hide |
Range on Protein: 248-328 Range on HMM: 11-92/92 Sequence Identity: 36% (30 aa) TVTEGKHARLSCYVTGEPKPETVWKKDGQLVTE-GRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVV .|.||. ||..| |||.|.|. .|.|||| ... ..||.. .| . | |. ....| | |||.|.| .|. ... . | EVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| IGc2 | Obscn.AA | IGc2 | 250-318 | 33 | 5.7e-10 | 40.36 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 250-318 Range on HMM: 1-56/56 Sequence Identity: 33% (23 aa) TEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVG || ..| | .|| | |. |.| || . | |.| . .|.|.|||.|.| .| HEGQSVTLTCPATGNPDPNIHWYK-GQPLP------------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| IG | Obscn.AA | IG | 244-329 | 20 | 4e-09 | 37.57 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 244-329 Range on HMM: 1-58/58 Sequence Identity: 20% (19 aa) TRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDR---GLYTCTASNLVGQTYS--SVLVVVR . || || ..|.| |. . |. | | . .| | |.|.|. ||..| .. . |. PP-VTVKEGETVTLTC-VS-----QIWWY-----------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ |
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| V-set | Obscn.AA | V-set | 237-328 | 16 | 0.417764 | 5.64 | Pfam | 1-128 (128) | Show / Hide |
Range on Protein: 237-328 Range on HMM: 1-128/128 Sequence Identity: 16% (21 aa) ASPPST-GTR----TCTVTEGKHARLSCYVT-GEPKPETV----WKKDGQLVTEGRRHVV---------------YEDAQENFV-----------LKILF .|. .. .| || ||. ..|.| .. . .|.. | .. | .. . .. |. .... |.| QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQ-QPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISN CKQSDRGLYTCTASNL-VGQTYSSVLVVV . || | |.| ..| .. ... ..| LQPSDSGTYYCAVWNCNEDYFGHGTRLTV |
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| IG | Obscn.AA | IG | 339-419 | 19 | 3.8e-08 | 34.31 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 339-419 Range on HMM: 1-58/58 Sequence Identity: 19% (17 aa) LQDLEVREKESATFLCEVPQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDD---AVYICETP--EGSR-TVAELAVQ . ..|.| |..|. | |. . |. ||. ||...| ..| |. ... ..| || PP-VTVKEGETVTLTC-VS----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| I-set | Obscn.AA | I-set | 333-404 | 33 | 1e-06 | 25.28 | Pfam | 1-75 (92) | Show / Hide |
Range on Protein: 333-404 Range on HMM: 1-75/92 Sequence Identity: 33% (26 aa) VPFKKRLQDLEVREKESATFLCEV---PQPSTEAAWFKEETRLWA-SAKYGIEEEG-TERRLTVRNVSADDDAVYIC | ....|.||.| |.|.| |.| |.| . ||| . | | .. . ..| . .||..|| .|| .| | PKFTQKPKDVEVQEGETARFECQVTGDPPP--QVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTC |
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| IGc2 | Obscn.AA | IGc2 | 345-411 | 22 | 0.000895 | 11.08 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 345-411 Range on HMM: 1-56/56 Sequence Identity: 22% (15 aa) REKESATFLCE-VPQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSR .| .|.|. |. | . |.| ...| .. .||..||. .|. .| |. HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| V-set | Obscn.AA | V-set | 332-404 | 12 | 2.915197 | 2.73 | Pfam | 1-110 (128) | Show / Hide |
Range on Protein: 332-404 Range on HMM: 1-110/128 Sequence Identity: 12% (14 aa) AVPFKK-RLQ----DLEVREKESATFLCEVP------QPSTEAAWFK-EET------------RLWAS---AKYGIEEEGTER-----R-----LTVRNV ... . ..| | .|.|. | . .... |.. . .. .. .|. . |... . || .|. QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNL SADDDAVYIC . .| ..| | QPSDSGTYYC |
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| I-set | Obscn.AA | I-set | 451-489 | 26 | 5.5e-05 | 19.42 | Pfam | 32-72 (92) | Show / Hide |
Range on Protein: 451-489 Range on HMM: 32-72/92 Sequence Identity: 26% (11 aa) VHWLRNQEEVVA-GGRVAISAEG-TRHTLTISQCCLEDVGQ | |... ... . |. ....| ..|||||... .| |. VSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGK |
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| IG | Obscn.AA | IG | 427-508 | 14 | 0.259067 | 2.36 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 427-508 Range on HMM: 1-58/58 Sequence Identity: 14% (13 aa) PRKTAVRVGDTAMFCVELAVPVGPVHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLEDV---GQVAFMAG-DCQTS-TQFCVSAP |. . |..|.|. . . ..|. ||| . .|| | .| ...| . .. PP-VTVKEGETVTLTC-VS----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| FN3 | Obscn.AA | FN3 | 513-598 | 20 | 1.4e-09 | 39.09 | SMART | 1-69 (69) | Show / Hide |
Range on Protein: 513-598 Range on HMM: 1-69/69 Sequence Identity: 20% (21 aa) LQPPVD---PVVKARMES------SVILSWSPPPHGERPVTIDGYLVEKKKLGTYTWIRCHEAEWVATPELTVADVAEE----GNFQFRVSALNS--FGQ || . ..|.. .. || |||.|| | || || . . . .|||.| |. |. PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP--------IVGYR------------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGE S . G |
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| I-set | Obscn.AA | I-set | 643-673 | 39 | 0.000486 | 16.22 | Pfam | 33-65 (92) | Show / Hide |
Range on Protein: 643-673 Range on HMM: 33-65/92 Sequence Identity: 39% (13 aa) EWFLDGQALKA-SSVYEIHCDR-TRHTLTIREV .|| ||| |. |. . ...| ..||||..| SWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNV |
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| IG | Obscn.AA | IG | 619-698 | 15 | 0.418898 | 0.55 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 619-698 Range on HMM: 1-58/58 Sequence Identity: 15% (13 aa) LKAVQAVEGGEVTFSVDLTVASAGEWFLDGQALKASSVYEIHCDRTRHTLTIREVPASLH--GAQLKFVAN--GIES--SIRMEVR . | ..||. ||.. . |. ||| .| .. .. .|. ..| ... .|. PP-VTVKEGETVTLTC-VS---QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| I-set | Obscn.AA | I-set | 626-638 | 38 | 11.633849 | 1.36 | Pfam | 80-92 (92) | Show / Hide |
Range on Protein: 626-638 Range on HMM: 80-92/92 Sequence Identity: 38% (5 aa) EGGEVTFSVDLTV ..||.. .. ||| SFGEAECTAELTV |
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| I-set | Obscn.AA | I-set | 737-779 | 35 | 2.8e-09 | 34.01 | Pfam | 32-76 (92) | Show / Hide |
Range on Protein: 737-779 Range on HMM: 32-76/92 Sequence Identity: 35% (16 aa) VTWLKDGRTLSP-GPKYEVQASA-GRRVLLVRDVARDDAGLYECV |.|.|||. |.| . .. .... |. | ...| .||.| |.|| VSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCV |
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| IG | Obscn.AA | IG | 804-884 | 17 | 4.4e-08 | 34.1 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 804-884 Range on HMM: 1-58/58 Sequence Identity: 17% (15 aa) GSCVDAVAGGPAQFECETSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDE---GTYSCRVG--EDSV--DFRLRVS . | ...|......| | ...|| |. |...|. ||| |.. ... ..|.|. PP-VTVKEGETVTLTC-VS----QIWWY-----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| I-set | Obscn.AA | I-set | 807-883 | 30 | 3.4e-05 | 20.16 | Pfam | 10-92 (92) | Show / Hide |
Range on Protein: 807-883 Range on HMM: 10-92/92 Sequence Identity: 30% (25 aa) VDAVAGGPAQFECETSEAHV-HVHWYKDGMELGHSGERFLQEDVG-TRHRLVAATVTRQDEGTYSCR----VGEDSVDFRLRV | . | | |||. . | |.||| .| ...|. .| ...| |.. |||.|.|. .||......| | VEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| IGc2 | Obscn.AA | IGc2 | 810-877 | 23 | 0.000305 | 15.56 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 810-877 Range on HMM: 1-56/56 Sequence Identity: 23% (16 aa) VAGGPAQFECE-TSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSCRVGEDSV |......|. | .|||| | .| .. .| ||. |.|.|.|.. HEGQSVTLTCPATGNPDPNIHWYK-GQPLP------------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| IGc2 | Obscn.AA | IGc2 | 721-785 | 19 | 0.000513 | 13.39 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 721-785 Range on HMM: 1-56/56 Sequence Identity: 19% (13 aa) HEEAQLLAELS---DQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRGGRI || .. . . .. ..|.| | |. .. | ...|...|.|.|.|. |. HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| IG | Obscn.AA | IG | 713-792 | 15 | 0.000777 | 19.99 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 713-792 Range on HMM: 1-58/58 Sequence Identity: 15% (14 aa) AREVLARLHEEAQLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDA---GLYECVSRGGRIAYQ-----LSVQ . |.... | ..| | ..|. | . .| ..|. | | |. . . ... |.|| PP-VTVKEGETVTLTC-VS----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQAT-HGQYWSIQGTTLTVQ |
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| V-set | Obscn.AA | V-set | 788-872 | 15 | 0.062309 | 8.49 | Pfam | 1-112 (128) | Show / Hide |
Range on Protein: 788-872 Range on HMM: 1-112/128 Sequence Identity: 15% (19 aa) QLSVQG-LAR---FLHKDMAGSCVDAVAGGPAQFECETS-EA----HV-HVHWYKDGMELGHSGERFL---------------QEDVGTRHR-------- |..|.. | . | .. |. . ..| | |. ...||.. .|.. . .. | . QSQVTQHPPRGCPW--------WVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQ-QPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKN ---LVAATVTRQDEGTYSCRV | ... |.||| | | DFSLTISNLQPSDSGTYYCAV |
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| I-set | Obscn.AA | I-set | 898-964 | 28 | 2.9e-12 | 44.15 | Pfam | 8-77 (92) | Show / Hide |
Range on Protein: 898-964 Range on HMM: 8-77/92 Sequence Identity: 28% (20 aa) RKLQAEAGASATLSCEVAQAQT-EVTWYKDGKKLSS-SSKVCMEATG-CTRRLVVQQAGQADAGEYSCEA . ... | .|...|.| . .|.|.|||..|.. |... | ..| | .| .... ..|.|.|.| | KDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVA |
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| IG | Obscn.AA | IG | 897-976 | 17 | 4e-09 | 37.55 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 897-976 Range on HMM: 1-58/58 Sequence Identity: 17% (15 aa) RRKLQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADA---GEYSCEAG--GQRL--SFHLDVK . . . .| ..||.| |. ...|| |.. .. .|. |.| |.| . ...| |. PP-VTVKEGETVTLTC-VS----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| IGc2 | Obscn.AA | IGc2 | 903-969 | 23 | 1.8e-05 | 25.42 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 903-969 Range on HMM: 1-56/56 Sequence Identity: 23% (16 aa) EAGASATLSCEVAQAQT-EVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQRL . | |.|| |... . . ...||| |..|. .| .. . .|.|.|.|.| . HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| V-set | Obscn.AA | V-set | 900-935 | 16 | 6.408505 | 1.55 | Pfam | 16-56 (128) | Show / Hide |
Range on Protein: 900-935 Range on HMM: 16-56/128 Sequence Identity: 16% (7 aa) LQAEAGASATLSCEVA------QAQTEVTWYKDGKKLSSSSK . .. |.|.||.| . .. . ..||.. .. .... VTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQ-QPPGQKPQ |
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| I-set | Obscn.AA | I-set | 992-1057 | 27 | 1.7e-11 | 41.52 | Pfam | 10-78 (92) | Show / Hide |
Range on Protein: 992-1057 Range on HMM: 10-78/92 Sequence Identity: 27% (19 aa) VQAEAGASATLSCEVAQAQT-EVMWYKDGKKLSS-SLKVHVEAKG-CRRRLVVQQAGKTDAGDYSCEAR |.. | .|...|.| . .| |.|||..|.. | .... ..| . .| .... . |.| |.| |. VEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVAT |
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| IG | Obscn.AA | IG | 989-1068 | 17 | 6.9e-10 | 40.1 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 989-1068 Range on HMM: 1-58/58 Sequence Identity: 17% (15 aa) HSEVQAEAGASATLSCEVAQAQTEVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDA---GDYSCEAR--GQRV--SFRLHIT . | . .| ..||.| |. .. || |.. .. . |. |.| |.|. . ...|... PP-VTVKEGETVTLTC-VS----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| IGc2 | Obscn.AA | IGc2 | 995-1061 | 25 | 2.1e-05 | 25.19 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 995-1061 Range on HMM: 1-56/56 Sequence Identity: 25% (17 aa) EAGASATLSCEVAQAQT-EVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEARGQRV . | |.|| |... . . ...||| |..|. . .| .. . . |.| |.|.||. HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| V-set | Obscn.AA | V-set | 985-1030 | 13 | 0.079769 | 8.12 | Pfam | 1-59 (128) | Show / Hide |
Range on Protein: 985-1030 Range on HMM: 1-59/128 Sequence Identity: 13% (8 aa) DQVAHS--------EVQAEAGASATLSCEVA------QAQTEVMWYKDGKKLSSSLKVHV ... . .| .. |.|.||.| . .. . . ||.. .. .... .. QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQ-QPPGQKPQWII |
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| I-set | Obscn.AA | I-set | 1084-1148 | 30 | 3.6e-12 | 43.8 | Pfam | 10-77 (92) | Show / Hide |
Range on Protein: 1084-1148 Range on HMM: 10-77/92 Sequence Identity: 30% (21 aa) VQAEAGASAMLSCEVAQAQT-EVTWYKDGKKLSS-SSKVGMEVKG-CTRRLVLPQAGKADAGEYSCEA |.. | .| ..|.| . .|.|.|||..|.. |... | .| | .| .. ..|.|.|.| | VEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVA |
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| IG | Obscn.AA | IG | 1081-1160 | 16 | 6.3e-10 | 40.22 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 1081-1160 Range on HMM: 1-58/58 Sequence Identity: 16% (14 aa) HNEVQAEAGASAMLSCEVAQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADA---GEYSCEAG--GQRV--SFHLHIT | . .| .. |.| |. ...|| |.. .. ..|. |.| |.| . ...|... PP-VTVKEGETVTLTC-VS----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| IGc2 | Obscn.AA | IGc2 | 1087-1153 | 22 | 6.5e-05 | 22.0 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 1087-1153 Range on HMM: 1-56/56 Sequence Identity: 22% (15 aa) EAGASAMLSCEVAQAQT-EVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEAGGQRV . | |. | |... . . ...||| |..|. .| . . ..|.|.|.|.| . HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| V-set | Obscn.AA | V-set | 1077-1119 | 14 | 0.283633 | 6.22 | Pfam | 1-56 (128) | Show / Hide |
Range on Protein: 1077-1119 Range on HMM: 1-56/128 Sequence Identity: 14% (8 aa) EQSVHN--------EVQAEAGASAMLSCEVA------QAQTEVTWYKDGKKLSSSSK ..|. .| .. |.|. |.| . .. . ..||.. .. .... QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQ-QPPGQKPQ |
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| I-set | Obscn.AA | I-set | 1176-1240 | 35 | 3.2e-14 | 50.79 | Pfam | 10-77 (92) | Show / Hide |
Range on Protein: 1176-1240 Range on HMM: 10-77/92 Sequence Identity: 35% (24 aa) VQAEAGTTAMLSCEV-AQPQTEVTWYKDGKKLSS-SSKVRMEVKG-CTRRLVVQQVGKADAGEYSCEA |.. | || ..|.| .|. .|.|.|||..|.. |....| .| | .| ...| ..|.|.|.| | VEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVA |
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| IG | Obscn.AA | IG | 1173-1252 | 18 | 4.2e-10 | 40.8 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 1173-1252 Range on HMM: 1-58/58 Sequence Identity: 18% (16 aa) HNEVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADA---GEYSCEAG--GQRV--SFQLHIT | . .| |. |.| |. ...|| |.. .| ..|. |.| |.| . ...|... PP-VTVKEGETVTLTC-VS----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| IGc2 | Obscn.AA | IGc2 | 1179-1245 | 23 | 2e-06 | 28.73 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 1179-1245 Range on HMM: 1-56/56 Sequence Identity: 23% (16 aa) EAGTTAMLSCE-VAQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRV . |... | |. . | ...||| |..|. .| .. | ..|.|.|.|.| . HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| V-set | Obscn.AA | V-set | 1169-1240 | 13 | 0.139766 | 7.28 | Pfam | 1-112 (128) | Show / Hide |
Range on Protein: 1169-1240 Range on HMM: 1-112/128 Sequence Identity: 13% (15 aa) EQSVHN--------EVQAEAGTTAMLSCEVA-------QPQTEVTWYKDGKKL-----------------------SSSSKVRMEVKGCTR----RLVVQ ..|. .| .. |... |.| . ... ..||.. .. ... | | .. |... | . QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNF-YIYWYRQ-QPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTIS QVGKADAGEYSCEA .. .| | | | . NLQPSDSGTYYCAV |
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| I-set | Obscn.AA | I-set | 1268-1332 | 29 | 6e-12 | 43.07 | Pfam | 10-77 (92) | Show / Hide |
Range on Protein: 1268-1332 Range on HMM: 10-77/92 Sequence Identity: 29% (20 aa) VRTEAGASATLSCEVAQAQT-EVTWYKDGKKLSS-SSKVRIEAAG-CMRQLVVQQAGQADAGEYTCEA | | .|...|.| . .|.|.|||..|.. |..... . | | .... ..|.|.||| | VEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVA |
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| IG | Obscn.AA | IG | 1265-1344 | 18 | 4.4e-09 | 37.41 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 1265-1344 Range on HMM: 1-58/58 Sequence Identity: 18% (16 aa) HNEVRTEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADA---GEYTCEAG--GQRL--SFHLDVS | .| ..||.| |. ...|| |.. .. .|. |.|.|.| . ...| |. PP-VTVKEGETVTLTC-VS----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| IGc2 | Obscn.AA | IGc2 | 1271-1337 | 25 | 4.4e-05 | 23.61 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 1271-1337 Range on HMM: 1-56/56 Sequence Identity: 25% (17 aa) EAGASATLSCEVAQAQT-EVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEAGGQRL . | |.|| |... . . ...||| |..|. | .. . .|.|.|||.| . HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| V-set | Obscn.AA | V-set | 1261-1332 | 15 | 0.000818 | 14.98 | Pfam | 1-112 (128) | Show / Hide |
Range on Protein: 1261-1332 Range on HMM: 1-112/128 Sequence Identity: 15% (17 aa) EQLVHN--------EVRTEAGASATLSCEVA------QAQTEVTWYKDGKKL-----------------------SSSSKVRIEAAGCMR----QLVVQQ . |. .|. . |.|.||.| . .. . ..||.. .. ... | |.. .|. . .| .. QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQ-QPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISN AGQADAGEYTCEA . .| | |.| . LQPSDSGTYYCAV |
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| IGv | Obscn.AA | IGv | 1275-1332 | 21 | 0.006322 | 0.25 | SMART | 1-76 (76) | Show / Hide |
Range on Protein: 1275-1332 Range on HMM: 1-76/76 Sequence Identity: 21% (16 aa) SATLSCEVAQAQTEVTWYKD-------GKKL-----SSSSKVRIEA------AGCMRQLVVQQAGQADAGEYTCEA |.||||.. . .....||. || | |..... . .. |. . .| | |.|. SVTLSCKFSGFTFYMHWYRQPPDSTPKGKGLEWMGYSYKGRFTWSKDNITRWSKNQFYLTMSNLRPEDTGTYYCAR |
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| I-set | Obscn.AA | I-set | 1358-1424 | 30 | 2.3e-12 | 44.49 | Pfam | 8-77 (92) | Show / Hide |
Range on Protein: 1358-1424 Range on HMM: 8-77/92 Sequence Identity: 30% (21 aa) RKVQAEAGAIATLSCEVAQAQT-EVTWYKDGKKLSS-SSKVRMEAVG-CTRRLVVQQACQADTGEYSCEA . |.. | |...|.| . .|.|.|||..|.. |....| ..| | .| .......|.|.|.| | KDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVA |
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| IG | Obscn.AA | IG | 1357-1436 | 19 | 2.6e-07 | 31.54 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 1357-1436 Range on HMM: 1-58/58 Sequence Identity: 19% (17 aa) HRKVQAEAGAIATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADT---GEYSCEAGGQRLSFS-----LDVA . | . .| .||.| |. ...|| |.. .. .|. |.| |.| .| | | PP-VTVKEGETVTLTC-VS----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQAT-HGQYWSIQGTTLTVQ |
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| IGc2 | Obscn.AA | IGc2 | 1363-1429 | 22 | 0.000213 | 17.04 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 1363-1429 Range on HMM: 1-56/56 Sequence Identity: 22% (15 aa) EAGAIATLSCEVAQAQT-EVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEAGGQRL . | .|| |... . . ...||| |..|. .| .. . .| |.|.|.| . HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| I-set | Obscn.AA | I-set | 1452-1527 | 26 | 7.4e-08 | 29.18 | Pfam | 10-92 (92) | Show / Hide |
Range on Protein: 1452-1527 Range on HMM: 10-92/92 Sequence Identity: 26% (22 aa) VQAQAGASTTLSCEVAQAQT-EVMWYKDGKKLSF-SSKVRMEAVG-CTRRLVVQQAGQAVAGEYSC----EAGSQRLSFHLHV |..| | . ...|.| . .| |.|||..|. |....| ..| | .| .... .. .|.|.| ..|.. ...| | VEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| IG | Obscn.AA | IG | 1449-1528 | 17 | 2e-06 | 28.47 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 1449-1528 Range on HMM: 1-58/58 Sequence Identity: 17% (15 aa) HREVQAQAGASTTLSCEVAQAQTEVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVA---GEYSCEAG--SQRL--SFHLHVA . | ...| . ||.| |. .. || |.. .. . . |.| |.| .. ...|.| PP-VTVKEGETVTLTC-VS----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| IGc2 | Obscn.AA | IGc2 | 1455-1521 | 22 | 0.000859 | 11.25 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 1455-1521 Range on HMM: 1-56/56 Sequence Identity: 22% (15 aa) QAGASTTLSCEVAQAQT-EVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAGEYSCEAGSQRL . | | || |... . . ...||| |..|. .| .. . . .|.|.|.| . HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| V-set | Obscn.AA | V-set | 1445-1477 | 21 | 0.924642 | 4.45 | Pfam | 1-47 (128) | Show / Hide |
Range on Protein: 1445-1477 Range on HMM: 1-47/128 Sequence Identity: 21% (10 aa) EQPVHR--------EVQAQAGASTTLSCEVA------QAQTEVMWYK ..|. .| .| |.| ||.| . .. . . ||. QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYR |
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| I-set | Obscn.AA | I-set | 1544-1608 | 30 | 1.3e-14 | 52.13 | Pfam | 10-77 (92) | Show / Hide |
Range on Protein: 1544-1608 Range on HMM: 10-77/92 Sequence Identity: 30% (21 aa) VQAEAGTSATLSCEVAQAQT-EVTWYKDGKKLSS-SSKVRMEAVG-CTRRLVVQEAGQADAGEYSCKA |.. | .|...|.| . .|.|.|||..|.. |....| ..| | .| .... ..|.|.|.|.| VEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVA |
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| IG | Obscn.AA | IG | 1541-1620 | 18 | 1.8e-10 | 42.02 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 1541-1620 Range on HMM: 1-58/58 Sequence Identity: 18% (16 aa) SREVQAEAGTSATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADA---GEYSCKAG--DQRL--SFHLHVA .. | . .| ..||.| |. ...|| |.. .. .|. |.| | | .. ...|.| PP-VTVKEGETVTLTC-VS----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| IGc2 | Obscn.AA | IGc2 | 1547-1613 | 23 | 4e-06 | 27.72 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 1547-1613 Range on HMM: 1-56/56 Sequence Identity: 23% (16 aa) EAGTSATLSCEVAQAQT-EVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKAGDQRL . |.|.|| |... . . ...||| |..|. .| .... .|.|.|.|.| HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| V-set | Obscn.AA | V-set | 1541-1579 | 18 | 0.370458 | 5.82 | Pfam | 9-56 (128) | Show / Hide |
Range on Protein: 1541-1579 Range on HMM: 9-56/128 Sequence Identity: 18% (9 aa) SR----EVQAEAGTSATLSCEVA------QAQTEVTWYKDGKKLSSSSK .| .| .. |.|.||.| . .. . ..||.. .. .... PRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQ-QPPGQKPQ |
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| I-set | Obscn.AA | I-set | 1636-1700 | 27 | 1.2e-11 | 42.02 | Pfam | 10-77 (92) | Show / Hide |
Range on Protein: 1636-1700 Range on HMM: 10-77/92 Sequence Identity: 27% (19 aa) VQAEAGASATLSCEVAQAQT-EVTWYKDGKKLSS-SSKVRVEAVG-CTRRLVVQQAGQAEAGEYSCEA |.. | .|...|.| . .|.|.|||..|.. |..... ..| | .| .... .. .|.|.| | VEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVA |
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| I-set | Obscn.AA | I-set | 1749-1793 | 38 | 7.3e-10 | 35.98 | Pfam | 31-77 (92) | Show / Hide |
Range on Protein: 1749-1793 Range on HMM: 31-77/92 Sequence Identity: 38% (18 aa) TVTWLKDGVEIRR-SKRHETASQG-DTHTLTVHGAQVLDSAIYSCRV .|.|.||| ..| |.|| | .|.|||. ..| |. .|.|.. QVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVA |
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| IG | Obscn.AA | IG | 1633-1712 | 17 | 1.3e-08 | 35.9 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 1633-1712 Range on HMM: 1-58/58 Sequence Identity: 17% (15 aa) HREVQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQAEA---GEYSCEAG--GQQL--SFRLQVA . | . .| ..||.| |. ...|| |.. .. . . |.| |.| .. ...|.| PP-VTVKEGETVTLTC-VS----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| IG | Obscn.AA | IG | 1725-1805 | 18 | 2.3e-07 | 31.7 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 1725-1805 Range on HMM: 1-58/58 Sequence Identity: 18% (16 aa) REPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDS---AIYSCRVG---AEG-QDFPVQVE . ..||| |.. || . ...|. ||. ..|. || ..| |.. ... | . ..|. PP-VTVKEGETVTLTC-VS-----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| IGc2 | Obscn.AA | IGc2 | 1639-1705 | 22 | 5.1e-05 | 22.99 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 1639-1705 Range on HMM: 1-56/56 Sequence Identity: 22% (15 aa) EAGASATLSCEVAQAQT-EVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQAEAGEYSCEAGGQQL . | |.|| |... . . ...||| |..|. .| .. . . .|.|.|.| . HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| IGc2 | Obscn.AA | IGc2 | 1731-1798 | 19 | 0.001209 | 9.83 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 1731-1798 Range on HMM: 1-56/56 Sequence Identity: 19% (13 aa) KEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRVGAEGQ .| ....|| . .....|.| | .. . |||. ... || .|.|.. . HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| IGv | Obscn.AA | IGv | 1643-1793 | 10 | 0.001493 | 6.53 | SMART | 1-76 (76) | Show / Hide |
Range on Protein: 1643-1793
Range on HMM: 1-76/76
Sequence Identity: 10% (16 aa)
SATLSCEVAQAQTEVTWYKD-------GKKLSSSSKVRVEAVGCTRRLVVQQAGQAEAGEYSCEAGGQQLSFRLQVAELEPQISERPCRREPLVVKEHED
|.||||.. . .....||. || |.
SVTLSCKFSGFTFYMHWYRQPPDSTPKGKGLEWMGY----------------------------------------------------------------
IILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRV
.|. ... .. .. . . . .|| .. .. |...| | .
----------------SYKGRFTWSKDNI-TR-WSKNQFYLTMSNLRPEDTGTYYCAR
|
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| V-set | Obscn.AA | V-set | 1727-1807 | 14 | 0.006524 | 11.87 | Pfam | 15-128 (128) | Show / Hide |
Range on Protein: 1727-1807 Range on HMM: 15-128/128 Sequence Identity: 14% (16 aa) PLVVKEHEDIILTATLATPS----AA-TVTWLK-DGV-----------------------EIRRSKRHETASQGD--THTLTVHGAQVLDSAIYSCRVGA ...|.| ... |. .. ... . ...| . . | ..| . ..... . .|| . .|. ||..| | | WVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNLQPSDSGTYYCAVWN --EGQDFPVQVEEV |.. . | CNEDYFGHGTRLTV |
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| V-set | Obscn.AA | V-set | 1633-1711 | 16 | 0.060263 | 8.54 | Pfam | 9-128 (128) | Show / Hide |
Range on Protein: 1633-1711 Range on HMM: 9-128/128 Sequence Identity: 16% (20 aa) HR----EVQAEAGASATLSCEVA------QAQTEVTWYKDGKKL-----------------------SSSSKVRVEAVGCTR----RLVVQQAGQAEAGE .| .| .. |.|.||.| . .. . ..||.. .. ... | ||. |... | ... . | PRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQ-QPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNLQPSDSGT YSCE-----AGGQQLSFRLQV | | .. . . ||.| YYCAVWNCNEDYFGHGTRLTV |
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| IG | Obscn.AA | IG | 1815-1894 | 21 | 2e-10 | 41.91 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 1815-1894 Range on HMM: 1-58/58 Sequence Identity: 21% (19 aa) LEPVCGELGGTVTLACELSPACAEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDA---GEYVCESR--DDHT--SAQLTVS . | . .|.|||| | | .. |. ||. ....||. |.|.|. . ... ...|||. PP-VTVKEGETVTLTC-VS----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| I-set | Obscn.AA | I-set | 1838-1880 | 31 | 6e-08 | 29.49 | Pfam | 31-75 (92) | Show / Hide |
Range on Protein: 1838-1880 Range on HMM: 31-75/92 Sequence Identity: 31% (14 aa) EVVWRCGNTQLRV-GKRFQMVAEG-PVRSLTVLGLRAEDAGEYVC .|.| ... .||. ..|.||...| .||... ..|.|.| | QVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTC |
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| IGc2 | Obscn.AA | IGc2 | 1821-1887 | 23 | 1e-05 | 26.31 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 1821-1887 Range on HMM: 1-56/56 Sequence Identity: 23% (16 aa) ELGGTVTLACE--LSPACAEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESRDDHT . |..||| |. .|. ... |. ...| .||. . ||.|.|.|. | . HEGQSVTLTCPATGNPD-PNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| V-set | Obscn.AA | V-set | 1864-1893 | 31 | 0.022888 | 9.99 | Pfam | 94-128 (128) | Show / Hide |
Range on Protein: 1864-1893 Range on HMM: 94-128/128 Sequence Identity: 31% (11 aa) SLTVLGLRAEDAGEYVCESRD-----DHTSAQLTV ||| |. .| | | | . . ... .||| SLTISNLQPSDSGTYYCAVWNCNEDYFGHGTRLTV |
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| I-set | Obscn.AA | I-set | 1899-1973 | 33 | 5.8e-14 | 49.89 | Pfam | 1-78 (92) | Show / Hide |
Range on Protein: 1899-1973 Range on HMM: 1-78/92 Sequence Identity: 33% (26 aa) VKFMSGLSTVVAEEGGEATFQCVVSPS-DVAVVWFRDGALLQP-SEKFAISQSG-ASHSLTISDLVLEDAGQITVEAE || .. |.. || |.|.| |. . . |.||.||. |.| |... ....| ..||||. .|.|. |. |. PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVAT |
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| IG | Obscn.AA | IG | 1905-1984 | 20 | 1.1e-09 | 39.42 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 1905-1984 Range on HMM: 1-58/58 Sequence Identity: 20% (18 aa) LSTVVAEEGGEATFQCVVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDA---GQITVEAE--GASS--SAALRVR . |.. ||. .|..| || . |. ||| .. .||. | . .|. ..| .. |.|. PP-VTVKEGETVTLTC-VS----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| V-set | Obscn.AA | V-set | 1902-1966 | 16 | 8.9e-05 | 18.3 | Pfam | 1-106 (128) | Show / Hide |
Range on Protein: 1902-1966 Range on HMM: 1-106/128 Sequence Identity: 16% (18 aa) MSGLST---------VVAEEGGEATFQCVVS-----PSDV-AVVWFR-DGA-------------LLQP----------SEKFAISQSGA--SHSLTISDL .| ... |...||. .|..| .| .... . |.| . . .. .... .|... . |||||.| QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNL VLEDAG ..| | QPSDSG |
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| IGc2 | Obscn.AA | IGc2 | 1911-1977 | 22 | 0.0004 | 14.43 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 1911-1977 Range on HMM: 1-56/56 Sequence Identity: 22% (15 aa) EEGGEATFQCVVSPSDVA-VVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGASS .||. .|..| .. .... . |.. | |. . .|||.. .||.| | .|... . HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| IG | Obscn.AA | IG | 1994-2073 | 18 | 2e-05 | 25.28 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 1994-2073 Range on HMM: 1-58/58 Sequence Identity: 18% (16 aa) LEPQTVEERSSVTLEVELTRPWPELRWTRNATALAPGKNVEIHAEGARHRLVLHNVGFADR---GFFGCETP--DDKT--QAKLTVE . .|| | ..|||. . ...|. |.. || ..| | . |. ... ..|||. PP-VTVKEGETVTLTC-VS----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| IGc2 | Obscn.AA | IGc2 | 2000-2066 | 22 | 0.005731 | 3.36 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 2000-2066 Range on HMM: 1-56/56 Sequence Identity: 22% (15 aa) EERSSVTLEVE-LTRPWPELRWTRNATALAPGKNVEIHAEGARHRLVLHNVGFADRGFFGCETPDDKT .| ||||. . .| |. .|.. . |. . .| . || ..|.| |. . HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| I-set | Obscn.AA | I-set | 1988-2055 | 23 | 0.009307 | 11.87 | Pfam | 1-71 (92) | Show / Hide |
Range on Protein: 1988-2055 Range on HMM: 1-71/92 Sequence Identity: 23% (17 aa) VLFKKKLEPQTVEERSSVTLEVELT-RPWPELRWTRNATALAP-GKNVEIHAEG-ARHRLVLHNVGFADRG | .|. ...| | .....|.. | | |. |... |.| .. . ....| ...| || .| | PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEG |
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| IG | Obscn.AA | IG | 2083-2162 | 18 | 0.006261 | 16.38 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 2083-2162 Range on HMM: 1-58/58 Sequence Identity: 18% (16 aa) LQAVEAREQGTATMEVQLSHADVDGSWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDS---GLMVFKAE--GVHT--SARLVVT . |...| .|.|.. | .|. ||. ...|||| | . |. .. ...| |. PP-VTVKEGETVTLTC-VS----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| I-set | Obscn.AA | I-set | 2108-2144 | 30 | 0.100043 | 8.37 | Pfam | 33-71 (92) | Show / Hide |
Range on Protein: 2108-2144 Range on HMM: 33-71/92 Sequence Identity: 30% (12 aa) SWTRDGLRFQQ-GPTCHLAVRG-PMHTLTLSGLRPEDSG ||..|| .. . .. .| .||| |. |.|.| SWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEG |
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| V-set | Obscn.AA | V-set | 2132-2144 | 61 | 8.596054 | 1.11 | Pfam | 94-106 (128) | Show / Hide |
Range on Protein: 2132-2144 Range on HMM: 94-106/128 Sequence Identity: 61% (8 aa) TLTLSGLRPEDSG .||.| |.|.||| SLTISNLQPSDSG |
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| I-set | Obscn.AA | I-set | 2166-2250 | 29 | 4.6e-12 | 43.46 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 2166-2250 Range on HMM: 1-92/92 Sequence Identity: 29% (27 aa) VSFSRPLQDVVTTEKEKVTLECELS-RPNVDVRWLKDGVELRA-GKTMAIAAQG-ACRSLTIYRCEFADQGVYVCDAH----DAQSSASVKV .|.....||. .| | ...||. . | .| |.||| .|| .. . . . | .|||.... .| |.| | | |...|...| PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| I-set | Obscn.AA | I-set | 2255-2339 | 36 | 4.4e-11 | 40.11 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 2255-2339 Range on HMM: 1-92/92 Sequence Identity: 36% (34 aa) IQIVRPLEDVEVMEKDGATFSCEVSHDEVPG-QWFWEGSKLRP-TDNVRIRQEG-RTYTLIYRRVLAEDAGEIQFVAEN----AESRAQLRV ...... ||||.| . |.|.|.|. | | .|| |..||| .| ......| ||||. ..| ..|.|. ||.| ||..|.| | PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| IG | Obscn.AA | IG | 2172-2251 | 22 | 7.3e-11 | 43.33 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 2172-2251 Range on HMM: 1-58/58 Sequence Identity: 22% (20 aa) LQDVVTTEKEKVTLECELSRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQ---GVYVCDAH--DAQS--SASVKVQ . |. | | |||.| | ..|. ||| . ...|. |.|.| |. ...| .. ..|| PP-VTVKEGETVTLTC-VS----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| IGc2 | Obscn.AA | IGc2 | 2178-2244 | 26 | 1.2e-07 | 32.66 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 2178-2244 Range on HMM: 1-56/56 Sequence Identity: 26% (18 aa) TEKEKVTLECE-LSRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDAHDAQS | . |||.|. .|. ...|.| | .| .||| . ...| |.|.| | . . HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| IG | Obscn.AA | IG | 2261-2340 | 20 | 5e-06 | 27.33 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 2261-2340 Range on HMM: 1-58/58 Sequence Identity: 20% (18 aa) LEDVEVMEKDGATFSCEVSHDEVPGQWFWEGSKLRPTDNVRIRQEGRTYTLIYRRVLAEDA---GEIQFVAE--NAES--RAQLRVK . |.|.| . .|..| || | .| |. .| .||. |. . .|. ...| ..|.|. PP-VTVKEGETVTLTC-VS------QIWWY--------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| V-set | Obscn.AA | V-set | 2165-2257 | 16 | 0.47111 | 5.46 | Pfam | 1-128 (128) | Show / Hide |
Range on Protein: 2165-2257 Range on HMM: 1-128/128 Sequence Identity: 16% (21 aa) PVSFSR-PLQ----DVVTTEKEKVTLECELS--R----PNVDVRWLKDGVELRAGKTMAI-------AA----------QGACR----------SLTIYR ... . | |. | ..|||.| .| . .| .. | .. . . . | . .| .. |||| QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQ-QPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISN CEFADQGVYVCDAHDAQSSASVKVQGRNIQI . .| |.| | . . . . .| . .. LQPSDSGTYYCAVWNC--NEDYFGHGTRLTV |
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| I-set | Obscn.AA | I-set | 2344-2428 | 30 | 5.7e-10 | 36.35 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 2344-2428 Range on HMM: 1-92/92 Sequence Identity: 30% (28 aa) VTLVRPLRDKIAMEKHRGVLECQVSRASA-QVRWFKGSQELQP-GPKYELVSDG-LYRKLIISDVHAEDEDTYTC----DAGDVKTSAQFFV . .....| ..| . .||||. || |||. |.|.| . .. . || .|.||.| ..|| .||| .| ....|. | PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| IG | Obscn.AA | IG | 2350-2429 | 19 | 5.5e-09 | 37.11 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 2350-2429 Range on HMM: 1-58/58 Sequence Identity: 19% (17 aa) LRDKIAMEKHRGVLECQVSRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDE---DTYTCDAG--DVKT--SAQFFVE . ..| . .|.| || |..|. |.| .| .||. ||.| | ... ... |. PP-VTVKEGETVTLTC-VS----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| V-set | Obscn.AA | V-set | 2343-2438 | 12 | 0.00648 | 11.88 | Pfam | 1-128 (128) | Show / Hide |
Range on Protein: 2343-2438 Range on HMM: 1-128/128 Sequence Identity: 12% (17 aa) PVTLVR-PLR----DKIAMEKHRGVLECQVS--R----ASAQVRWFK-GSQELQPGPKYELVS---------------DGLYRK--------------LI .... | | . | . |.|..| . .. .. |.. ... |.| .... . ... | QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPP----GQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLT ISDVHAEDEDTYTCDAGDVKTSAQFFVEEQSITIVRG ||... .|. ||.| . . .. .. | .. ISNLQPSDSGTYYCAVWNC-----NEDYFGHGTRLTV |
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| I-set | Obscn.AA | I-set | 2433-2457 | 32 | 24.361193 | 0.27 | Pfam | 1-25 (92) | Show / Hide |
Range on Protein: 2433-2457 Range on HMM: 1-25/92 Sequence Identity: 32% (8 aa) ITIVRGLQDVTVMEPAPAWFECETS .... ..||.|.| | |||. . PKFTQKPKDVEVQEGETARFECQVT |
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| I-set | Obscn.AA | I-set | 2522-2607 | 30 | 2.5e-18 | 64.73 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 2522-2607 Range on HMM: 1-92/92 Sequence Identity: 30% (28 aa) PVVLTRPLEPKTGRELQSVVLSCDFRPAPK-AVQWYKDDTPLSP-SEKFKMSLEG-QMAELRILRLMPADAGVYRCQA----GSAHSSTEVTV |.....| . . .| ... ..|. . |. |.|.||. ||.| |....|. .| . . |.|.. |.|.|.|.|.| |.| .. |.|| PKFTQKP-KDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| IG | Obscn.AA | IG | 2529-2608 | 22 | 4.8e-13 | 50.57 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 2529-2608 Range on HMM: 1-58/58 Sequence Identity: 22% (20 aa) LEPKTGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADA---GVYRCQAG--SAHS--STEVTVE . |..| ..|.|.| . ..|| |.| .. |.|. |.|.||| ...| .|..||. PP-VTVKEGETVTLTC-VS----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| IGc2 | Obscn.AA | IGc2 | 2535-2601 | 27 | 1.6e-09 | 38.85 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 2535-2601 Range on HMM: 1-56/56 Sequence Identity: 27% (19 aa) RELQSVVLSCD-FRPAPKAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQAGSAHS .| |||.| |. ..||| ..||. .|.| . |.|.|.|.|.| .... HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| V-set | Obscn.AA | V-set | 2522-2607 | 17 | 1.4e-07 | 27.92 | Pfam | 1-128 (128) | Show / Hide |
Range on Protein: 2522-2607 Range on HMM: 1-128/128 Sequence Identity: 17% (23 aa) PVVLTR-PLE----PKTGRELQSVVLSCDFR-PA----PK-AVQWYK-DDT-------------------------PLSPSEKFKMSLEGQMAELRILRL ....| | . . |. | ||| |.| .. . . ..||. .. . . .. | .. . . |.| | QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNL MPADAGVYRCQAGS-----AHSSTEVTV |.| |.| |.. . ...|..|| QPSDSGTYYCAVWNCNEDYFGHGTRLTV |
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| IGv | Obscn.AA | IGv | 2539-2596 | 22 | 0.001875 | 5.54 | SMART | 1-76 (76) | Show / Hide |
Range on Protein: 2539-2596 Range on HMM: 1-76/76 Sequence Identity: 22% (17 aa) SVVLSCDFRPAPKAVQWYKD-----------DTPLSPSEKFKMSLEGQM--------AELRILRLMPADAGVYRCQA || ||| | . . ||. .. | | . .. ... . |.. .| |.| |.| |. SVTLSCKFSGFTFYMHWYRQPPDSTPKGKGLEWMGY-SYKGRFTWSKDNITRWSKNQFYLTMSNLRPEDTGTYYCAR |
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| I-set | Obscn.AA | I-set | 2612-2680 | 26 | 3.6e-08 | 30.22 | Pfam | 1-72 (92) | Show / Hide |
Range on Protein: 2612-2680 Range on HMM: 1-72/92 Sequence Identity: 26% (19 aa) VTVTGPLQDAEATEEGWASFSCELSHEDE-EVEWSLNGMPLYN-DSFHEISHKG-RRHTLVLKSIQRADAGI ..| ...|.|..| | |.|. . . . .|.| .| || . .. | .. .| ..|| . .|..|.|. PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGK |
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| IG | Obscn.AA | IG | 2618-2697 | 11 | 0.016723 | 12.68 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 2618-2697 Range on HMM: 1-58/58 Sequence Identity: 11% (10 aa) LQDAEATEEGWASFSCELSHEDEEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADA---GIVRASSL--KVST--SARLEVR . .. | . ....| | .. |. |.. ..|..|. |. . ... ...|.|. PP-VTVKEGETVTLTC-VS----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| I-set | Obscn.AA | I-set | 2701-2785 | 33 | 1.1e-13 | 48.95 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 2701-2785 Range on HMM: 1-92/92 Sequence Identity: 33% (31 aa) VVFLKALDDLSAEERGTLALQCEVS-DPEAHVVWRKDGVQLGP-SDKYDFLHTA-GTRGLVVHDVSPEDAGLYTCH----VGSEETRARVRV .|.. . |. . | |. ..|.|. ||. |.| ||| .| | ||.. . . || | . .| |.|.| ||| .|. |..|.. | PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| IG | Obscn.AA | IG | 2707-2786 | 18 | 1.9e-11 | 45.29 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 2707-2786 Range on HMM: 1-58/58 Sequence Identity: 18% (16 aa) LDDLSAEERGTLALQCEVSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDA---GLYTCHVG--SEET--RARVRVH ... | .|. |.| || .. |. |.. .|.|||. | |.| . . . ....|. PP-VTVKEGETVTLTC-VS----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| IGc2 | Obscn.AA | IGc2 | 2713-2779 | 25 | 1.9e-08 | 35.33 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 2713-2779 Range on HMM: 1-56/56 Sequence Identity: 25% (17 aa) EERGTLALQCE-VSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEET .| ... |.|. .|.. . |.| | .| . | . .|.|||.|.||| . .. HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| V-set | Obscn.AA | V-set | 2757-2785 | 26 | 0.006102 | 11.97 | Pfam | 95-128 (128) | Show / Hide |
Range on Protein: 2757-2785 Range on HMM: 95-128/128 Sequence Identity: 26% (9 aa) LVVHDVSPEDAGLYTCHVGS-----EETRARVRV | ....|.| | |.| | . .. |..| LTISNLQPSDSGTYYCAVWNCNEDYFGHGTRLTV |
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| I-set | Obscn.AA | I-set | 2824-2860 | 30 | 0.00092 | 15.28 | Pfam | 34-72 (92) | Show / Hide |
Range on Protein: 2824-2860 Range on HMM: 34-72/92 Sequence Identity: 30% (12 aa) WTVGGKTVGS-SSRFQATRQG-RKYILVVREAAPSDAGE |. .|. . . |.|.| |. | | | .... |.|.|. WFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGK |
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| IG | Obscn.AA | IG | 2796-2877 | 15 | 0.004456 | 17.47 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 2796-2877 Range on HMM: 1-58/58 Sequence Identity: 15% (14 aa) LKTMEVLEGESCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDA---GEVVFSVR--GLTS--KASLIVR . ..| |||. ...| | |. |.. .. |.|. |. . .. .| . |.|. PP-VTVKEGETVTLTC-VS------QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| I-set | Obscn.AA | I-set | 2790-2811 | 45 | 0.009759 | 11.8 | Pfam | 1-22 (92) | Show / Hide |
Range on Protein: 2790-2811 Range on HMM: 1-22/92 Sequence Identity: 45% (10 aa) VGITKRLKTMEVLEGESCSFEC .|...| .|| |||.. ||| PKFTQKPKDVEVQEGETARFEC |
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| IG | Obscn.AA | IG | 2887-2966 | 19 | 3.1e-13 | 51.23 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 2887-2966 Range on HMM: 1-58/58 Sequence Identity: 19% (17 aa) LEDQWVAPGEDVELRCELSRAGTPVHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDA---GEYTCEVE--ASKS--TASLHVE . ..| .||.|.|.| | ..|. |.| .... |. |.|.|... .| .. |.|. PP-VTVKEGETVTLTC-VS----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| I-set | Obscn.AA | I-set | 2881-2965 | 26 | 3.9e-10 | 36.89 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 2881-2965 Range on HMM: 1-92/92 Sequence Identity: 26% (24 aa) AAIIKPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRK-SQKYDVVCEG-TMAMLVIRGASLKDAGEYTCEVE----ASKSTASLHV ..... |. | ||.... |. . .| | |.|| . .| |... ....| . | |... |.|.||| .. ...||.| | PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| IGc2 | Obscn.AA | IGc2 | 2893-2959 | 22 | 1.2e-07 | 32.7 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 2893-2959 Range on HMM: 1-56/56 Sequence Identity: 22% (15 aa) APGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVEASKS .|..|.|.|. . . .| .||.| . . . | |. ... |.|.|||... ... HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| V-set | Obscn.AA | V-set | 2892-2965 | 16 | 0.003954 | 12.62 | Pfam | 18-128 (128) | Show / Hide |
Range on Protein: 2892-2965
Range on HMM: 18-128/128
Sequence Identity: 16% (18 aa)
VAPGEDVELRCELS-RA----GT-PVHWLK-DRK---------------AIRKSQKYDVVCEGTMA-----M-----LVIRGASLKDAGEYTCEVEA---
|..|..|.|.| .| .. ..| . . . ....| .. |. | |. ... | | |.| |
VQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNLQPSDSGTYYCAVWNCNE
--SKSTASLHV
. |.|
DYFGHGTRLTV
|
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| IG | Obscn.AA | IG | 2976-3055 | 21 | 3.4e-11 | 44.45 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 2976-3055 Range on HMM: 1-58/58 Sequence Identity: 21% (19 aa) LTNLQVEEKGTAVFTCKTEHPAATVTWRKGLLELRASGKHQPSQEGLTLRLTISALEKADS---DTYTCDIG--QAQS--RAQLLVQ . | | .|...|| . ...|. ||| ....|| ||.| |..| ..| || PP-VTVKEGETVTLTC-VS----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| I-set | Obscn.AA | I-set | 2970-3054 | 35 | 1.1e-08 | 31.92 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 2970-3054 Range on HMM: 1-92/92 Sequence Identity: 35% (33 aa) NCFTEELTNLQVEEKGTAVFTCK-TEHPAATVTWRKGLLELRA-SGKHQPSQEG-LTLRLTISALEKADSDTYTC----DIGQAQSRAQLLV .|| .....| | || |.|. | .| .|.| |. .|| | .|| ...| | .|||| ...|. .||| |.|...|.| | PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| IGc2 | Obscn.AA | IGc2 | 2982-3048 | 23 | 0.000109 | 19.84 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 2982-3048 Range on HMM: 1-56/56 Sequence Identity: 23% (16 aa) EEKGTAVFTCK-TEHPAATVTWRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTCDIGQAQS .| .....||. | |.....|.| .| .|||. ...|| .||| . . HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| V-set | Obscn.AA | V-set | 2969-3054 | 15 | 0.000239 | 16.82 | Pfam | 1-128 (128) | Show / Hide |
Range on Protein: 2969-3054 Range on HMM: 1-128/128 Sequence Identity: 15% (20 aa) ANCFTE-ELT----NLQVEEKGTAVFTCKTE--H----PAATVTWRK-GLL-----------------------ELRASGKHQPSQEGL--TLRLTISAL . | . . |.| ... ..|. . . ...| . . . . | .|. . |. . .. |||| | QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNL EKADSDTYTCDIGQ-----AQSRAQLLV . .|| ||.| . .. .| | QPSDSGTYYCAVWNCNEDYFGHGTRLTV |
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| IGv | Obscn.AA | IGv | 2986-3043 | 16 | 0.005105 | 1.18 | SMART | 1-76 (76) | Show / Hide |
Range on Protein: 2986-3043 Range on HMM: 1-76/76 Sequence Identity: 16% (13 aa) TAVFTCKTEHPAATVTWRKG---------LLELRASGKHQPSQEGLTLRL-------------TISALEKADSDTYTCDI .. .||. . ...| . ||. .. ... .|. |.| |. .|..||.|.. SVTLSCKFSGFTFYMHWYRQPPDSTPKGKGLEWMGY----SYKGRFTWSKDNITRWSKNQFYLTMSNLRPEDTGTYYCAR |
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| IG | Obscn.AA | IG | 3065-3146 | 20 | 1.1e-08 | 36.07 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 3065-3146 Range on HMM: 1-58/58 Sequence Identity: 20% (18 aa) LEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDS---GTIYFEAG--DQRA--SAALRVT . | |.||...|..| .| ..|. ||. .. . || || | .| .. . .. |.|. PP-VTVKEGETVTLTC-VS-----QIWWY-----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| I-set | Obscn.AA | I-set | 3059-3083 | 36 | 0.001355 | 14.71 | Pfam | 1-25 (92) | Show / Hide |
Range on Protein: 3059-3083 Range on HMM: 1-25/92 Sequence Identity: 36% (9 aa) VHIIEDLEDVDVQEGSSATFRCRIS ... . || ||||..|.| |... PKFTQKPKDVEVQEGETARFECQVT |
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| IGc2 | Obscn.AA | IGc2 | 3071-3139 | 21 | 0.008026 | 1.96 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 3071-3139 Range on HMM: 1-56/56 Sequence Identity: 21% (15 aa) QEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSGTIYFEAGDQRA .|| |.|..|. . . .||. .|| . ||.. .. |||. .| HEGQSVTLTCPATGNPDPNIHWYK-GQPLP------------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| V-set | Obscn.AA | V-set | 3058-3097 | 19 | 1.566859 | 3.66 | Pfam | 1-51 (128) | Show / Hide |
Range on Protein: 3058-3097 Range on HMM: 1-51/128 Sequence Identity: 19% (10 aa) RVHIIE-DLE----DVDVQEGSSATFRCRIS----PANYE-PVHWFL-DKT . . . . | |||| |.|..| | . . . ..|. .. QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPP |
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| I-set | Obscn.AA | I-set | 3150-3223 | 31 | 3.8e-14 | 50.53 | Pfam | 1-77 (92) | Show / Hide |
Range on Protein: 3150-3223 Range on HMM: 1-77/92 Sequence Identity: 31% (24 aa) SVFSRELTDATITEGEDLTLVCETSTC-DIPVCWTKDGKTLRG-SARCQLSHEG-HRAQLLITGATLQDSGRYKCEA .|.. ..|....|||.... |. . . . | |.|||. || | |.| . .| .. | |.... |.| |.| | PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVA |
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| IG | Obscn.AA | IG | 3245-3324 | 22 | 5.9e-12 | 46.97 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 3245-3324 Range on HMM: 1-58/58 Sequence Identity: 22% (20 aa) LKDLEVLEGGAATLRCVLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDS---GRYSCSFG--DQTT--SATLTVT . ..| ||. .||.| | ..| |.. |..|.|| | | | ... ..||||. PP-VTVKEGETVTLTC-VS----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| IG | Obscn.AA | IG | 3156-3237 | 20 | 1.5e-08 | 35.62 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 3156-3237
Range on HMM: 1-58/58
Sequence Identity: 20% (18 aa)
LTDATITEGEDLTLVCETSTCDIPVCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDS---GRYKCEAGGACSSS--IVRVHAR
| |||..|| | | . |. | | .....|| | | |.| . . .| .... .
PP-VTVKEGETVTLTC-VS----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ
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| IGc2 | Obscn.AA | IGc2 | 3162-3228 | 29 | 2.4e-07 | 31.65 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 3162-3228 Range on HMM: 1-56/56 Sequence Identity: 29% (20 aa) TEGEDLTLVCE-TSTCDIPVCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACS ||...|| |. | | . |.| |. | .. | |. .|. |||.| |.| .. . HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| I-set | Obscn.AA | I-set | 3269-3323 | 34 | 2.4e-07 | 27.44 | Pfam | 32-92 (92) | Show / Hide |
Range on Protein: 3269-3323 Range on HMM: 32-92/92 Sequence Identity: 34% (21 aa) VKWCYGNNVLRP-GDKYSLRQEG-AMLELVVRNLRPQDSGRYSC----SFGDQTTSATLTV | | ... ||| .|... ...| | ..| | |.| |.| ||| ....|.||| VSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| V-set | Obscn.AA | V-set | 3238-3323 | 15 | 2e-06 | 23.87 | Pfam | 1-128 (128) | Show / Hide |
Range on Protein: 3238-3323 Range on HMM: 1-128/128 Sequence Identity: 15% (20 aa) PVRFQE-ALK----DLEVLEGGAATLRCVLS-----SVAA-PVKWCY-GNN------------VLRPG-----------DKYSLRQEGA--MLELVVRNL .. . . ..| ||. .||.| .| . . . |.. .. . .. ..... . . . | .|| QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNL RPQDSGRYSCSFGD-----QTTSATLTV .| ||| | | . .. .||| QPSDSGTYYCAVWNCNEDYFGHGTRLTV |
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| IGc2 | Obscn.AA | IGc2 | 3251-3317 | 22 | 2.1e-05 | 25.2 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 3251-3317 Range on HMM: 1-56/56 Sequence Identity: 22% (15 aa) LEGGAATLRCV-LSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSCSFGDQTT .||...||.| . .. ..| . . | .| ..| .| |||.|.|. HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| V-set | Obscn.AA | V-set | 3150-3236 | 13 | 0.001297 | 14.29 | Pfam | 1-128 (128) | Show / Hide |
Range on Protein: 3150-3236 Range on HMM: 1-128/128 Sequence Identity: 13% (17 aa) SVFSRE--LT----DATITEGEDLTLVCETS--T----CDIPVCWTKDGKTL---------------------RGSARCQLSHE------GHRAQLLITG ... . | ||...|| | | . . . | .. .. . . |.. . . .....| |. QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQ-QPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISN ATLQDSGRYKCEAGGA---CSSSIVRVHA ... ||| | | . . . .|.. LQPSDSGTYYCAVWNCNEDYFGHGTRLTV |
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| IGv | Obscn.AA | IGv | 3255-3312 | 17 | 0.005793 | 0.63 | SMART | 1-76 (76) | Show / Hide |
Range on Protein: 3255-3312 Range on HMM: 1-76/76 Sequence Identity: 17% (14 aa) AATLRCVLSSV----------------AAPVKWCYGNNVLRPGDKYSLRQEG------AMLELVVRNLRPQDSGRYSCSF .|| | .| . ...|... ..... |. .|||| |.|.| |.. SVTLSCKFSGFTFYMHWYRQPPDSTPKGKGLEWMGY----SYKGRFTWSKDNITRWSKNQFYLTMSNLRPEDTGTYYCAR |
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| I-set | Obscn.AA | I-set | 3239-3260 | 40 | 0.013983 | 11.27 | Pfam | 1-22 (92) | Show / Hide |
Range on Protein: 3239-3260 Range on HMM: 1-22/92 Sequence Identity: 40% (9 aa) VRFQEALKDLEVLEGGAATLRC .|. .||.|| || .|.. | PKFTQKPKDVEVQEGETARFEC |
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| IG | Obscn.AA | IG | 3334-3412 | 17 | 1.4e-07 | 32.4 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 3334-3412 Range on HMM: 1-58/58 Sequence Identity: 17% (15 aa) LRNKEATEGATATLRCELSKAAPVEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDA---AEYSCVCG--EERT--SASLTIR . .. || |.||.| | . |. |.| .. . |. ..| |. . .. ||.. PP-VTVKEGETVTLTC-VS---QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| I-set | Obscn.AA | I-set | 3328-3411 | 31 | 8e-07 | 25.66 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 3328-3411 Range on HMM: 1-92/92 Sequence Identity: 31% (29 aa) AQFIGKLRNKEATEGATATLRCELSKAAP--VEWRKGSETLRD-GDRYCLRQDG-AMCELQIRGLAMVDAAEYSCV----CGEERTSASLTI .|. |... |..|| ||.. |. . | |.| |. . || .||. ..|| . | |.. |. .|.|| || ..|.||. PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| IGc2 | Obscn.AA | IGc2 | 3340-3405 | 19 | 0.000123 | 19.32 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 3340-3405 Range on HMM: 1-56/56 Sequence Identity: 19% (13 aa) TEGATATLRCE--LSKAAPVEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSCVCGEERT || ..||.|. . .. . |.| .. | .|.|. .. |. .|.|. . HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| V-set | Obscn.AA | V-set | 3328-3399 | 14 | 0.167375 | 7.01 | Pfam | 1-111 (128) | Show / Hide |
Range on Protein: 3328-3399 Range on HMM: 1-111/128 Sequence Identity: 14% (16 aa) AQFIGK--LR----NKEATEGATATLRCELS-------KAAPVEWRK-GSE-----------------------TLRDGDRYCLRQDGA--MCELQIRGL .... | .. ||...||.| .| . | . .. . | .|. . ... . |.|. | QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNL AMVDAAEYSCV . | . | |. QPSDSGTYYCA |
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| I-set | Obscn.AA | I-set | 3416-3499 | 33 | 7.9e-11 | 39.25 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 3416-3499 Range on HMM: 1-92/92 Sequence Identity: 33% (31 aa) AHFIGRLRHQESIEGATATLRCELSKAAP--VEWRKGRESLRD-GDRHSLRQDG-AVCELQICGLAVADAGEYSCV----CGEERTSATLTV .|. ... .| || ||.. |. . | |.| |. . || .|||. ..|| . | | . .|.|.|.|| || ..|.||| PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| IG | Obscn.AA | IG | 3422-3500 | 20 | 4.7e-10 | 40.65 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 3422-3500 Range on HMM: 1-58/58 Sequence Identity: 20% (18 aa) LRHQESIEGATATLRCELSKAAPVEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADA---GEYSCVCG--EERT--SATLTVK . .. || |.||.| | . |. |.| .. ..|. |.| |. . ..||||. PP-VTVKEGETVTLTC-VS---QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| IGc2 | Obscn.AA | IGc2 | 3428-3493 | 20 | 9e-06 | 26.41 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 3428-3493 Range on HMM: 1-56/56 Sequence Identity: 20% (14 aa) IEGATATLRCE--LSKAAPVEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEYSCVCGEERT .|| ..||.|. . .. . |.| ..| .|.| ...|.|.|.|. . HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| V-set | Obscn.AA | V-set | 3429-3499 | 17 | 0.524222 | 5.3 | Pfam | 20-128 (128) | Show / Hide |
Range on Protein: 3429-3499 Range on HMM: 20-128/128 Sequence Identity: 17% (19 aa) EGATATLRCELS-------KAAPVEWRK-GRE-----------------------SLRDGDRHSLRQDGA--VCELQICGLAVADAGEYSCVCGE----- ||...||.| .| . | . .. . | .| .. ... . |.| | ..| | | |. EGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNLQPSDSGTYYCAVWNCNEDY ERTSATLTV .. .||| FGHGTRLTV |
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| IG | Obscn.AA | IG | 3510-3588 | 19 | 3.6e-08 | 34.4 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 3510-3588 Range on HMM: 1-58/58 Sequence Identity: 19% (17 aa) LRNEEAVEGATAMLWCELSKVAPVEWRKGPENLRDGDRYILRQEGTRCELQICGLAMADA---GEYLCVCG--QERT--SATLTIR . ...|| |. | | | . |. |.| .. ..|. |.| |. | ..|||.. PP-VTVKEGETVTLTC-VS---QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| I-set | Obscn.AA | I-set | 3504-3587 | 31 | 5.4e-05 | 19.47 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 3504-3587 Range on HMM: 1-92/92 Sequence Identity: 31% (29 aa) AKFTEGLRNEEAVEGATAMLWCELSKVAP--VEWRKGPENLRD-GDRYILRQEG-TRCELQICGLAMADAGEYLCV----CGQERTSATLTI ||| ... |. || || . |. . | |.| |. . || .||. ...| .. | | . .|.|.| || |. ..|.||. PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| IGc2 | Obscn.AA | IGc2 | 3516-3581 | 19 | 0.000406 | 14.37 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 3516-3581 Range on HMM: 1-56/56 Sequence Identity: 19% (13 aa) VEGATAMLWCE--LSKVAPVEWRKGPENLRDGDRYILRQEGTRCELQICGLAMADAGEYLCVCGQERT || .. | |. . .. . |.| . | .. .|.| ...|.|.| |. . HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| V-set | Obscn.AA | V-set | 3503-3575 | 15 | 15.464589 | 0.23 | Pfam | 1-111 (128) | Show / Hide |
Range on Protein: 3503-3575 Range on HMM: 1-111/128 Sequence Identity: 15% (17 aa) PAKFTE-GLR----NEEAVEGATAMLWCELS-------KVAPVEWRK-GPE-------------NLRD----------GDRYILRQEGT--RCELQICGL . | | ...||... | | .| . . | . .| . .. .|. . . .. .. |.| | QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNL AMADAGEYLCV ..| | | |. QPSDSGTYYCA |
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| IG | Obscn.AA | IG | 3598-3676 | 18 | 2.5e-10 | 41.58 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 3598-3676 Range on HMM: 1-58/58 Sequence Identity: 18% (16 aa) VKNQEAREGATAVLQCELNSAAPVEWRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADT---GEYSCVCG--QERT--SAMLTVR . ....|| |..|.| . . |. |.| .. ..|. |.| |. | .. |||. PP-VTVKEGETVTLTC-VS---QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| I-set | Obscn.AA | I-set | 3592-3675 | 32 | 4.7e-09 | 33.24 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 3592-3675 Range on HMM: 1-92/92 Sequence Identity: 32% (30 aa) ARFIEDVKNQEAREGATAVLQCELNSAAP--VEWRKGSETLRD-GDRYSLRQDG-TKCELQIRGLAMADTGEYSCV----CGQERTSAMLTV .|. |..|..|| || ..|. | |.| |. . || .||.. ..|| . | |.. .|.|.|.|| |. ..| ||| PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| IGc2 | Obscn.AA | IGc2 | 3604-3669 | 20 | 5.3e-08 | 33.84 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 3604-3669 Range on HMM: 1-56/56 Sequence Identity: 20% (14 aa) REGATAVLQCE--LNSAAPVEWRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQERT .|| ...|.|. | .. . |.| .. | .. .|.|. ...| |.|.|. . HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| V-set | Obscn.AA | V-set | 3605-3675 | 15 | 0.005521 | 12.12 | Pfam | 20-128 (128) | Show / Hide |
Range on Protein: 3605-3675 Range on HMM: 20-128/128 Sequence Identity: 15% (17 aa) EGATAVLQCELN-------SAAPVEWRK-GSE-----------------------TLRDGDRYSLRQDGT--KCELQIRGLAMADTGEYSCV-----CGQ ||... |.| . . . | . .. . | .|... .... .. |.|. | ..|.| | |. .. EGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNLQPSDSGTYYCAVWNCNEDY ERTSAMLTV .. .||| FGHGTRLTV |
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| IG | Obscn.AA | IG | 3686-3764 | 19 | 8.2e-10 | 39.84 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 3686-3764 Range on HMM: 1-58/58 Sequence Identity: 19% (17 aa) LRNEEATEGATAVLRCELSKMAPVEWWKGHETLRDGDRHSLRQDGARCELQIRGLVAEDA---GEYLCMCG--KERT--SAMLTVR . .. || |..|.| | . |. |.| .. .||. |.| |. . .. |||. PP-VTVKEGETVTLTC-VS---QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| IGc2 | Obscn.AA | IGc2 | 3692-3757 | 20 | 0.00012 | 19.44 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 3692-3757 Range on HMM: 1-56/56 Sequence Identity: 20% (14 aa) TEGATAVLRCE--LSKMAPVEWWKGHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLCMCGKERT || ...|.|. . . . | | . | . .|.|. ||.|.| | . HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| I-set | Obscn.AA | I-set | 3709-3763 | 34 | 0.000183 | 17.66 | Pfam | 32-92 (92) | Show / Hide |
Range on Protein: 3709-3763 Range on HMM: 32-92/92 Sequence Identity: 34% (21 aa) VEWWKGHETLRD-GDRHSLRQDG-ARCELQIRGLVAEDAGEYLC----MCGKERTSAMLTV |.| |. . || .|||. ..|| .. | |.. ..|.|.| | |. ..| ||| VSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| V-set | Obscn.AA | V-set | 3679-3750 | 15 | 0.005632 | 12.09 | Pfam | 1-110 (128) | Show / Hide |
Range on Protein: 3679-3750 Range on HMM: 1-110/128 Sequence Identity: 15% (17 aa) PIKFTE-GLR----NEEATEGATAVLRCELS-------KMAPVEWWK-GHE-----------------------TLRDGDRHSLRQDGA--RCELQIRGL .. | | .. ||... |.| .| . . | . . . | .| .. ... .. |.|. | QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNL VAEDAGEYLC .| | | | QPSDSGTYYC |
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| I-set | Obscn.AA | I-set | 3680-3702 | 39 | 1.914417 | 4.02 | Pfam | 1-23 (92) | Show / Hide |
Range on Protein: 3680-3702 Range on HMM: 1-23/92 Sequence Identity: 39% (9 aa) IKFTEGLRNEEATEGATAVLRCE ||| ... |..|| || . |. PKFTQKPKDVEVQEGETARFECQ |
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| IG | Obscn.AA | IG | 3862-3940 | 20 | 5.1e-12 | 47.18 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 3862-3940 Range on HMM: 1-58/58 Sequence Identity: 20% (18 aa) VKNQEAREGATAVLQCELSKAAPVEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADT---GEYSCVCG--QERT--SATLTVR . ....|| |..|.| | . |. |.| .....|. |.| |. | ..||||. PP-VTVKEGETVTLTC-VS---QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| IG | Obscn.AA | IG | 3774-3852 | 22 | 1.2e-10 | 42.59 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 3774-3852 Range on HMM: 1-58/58 Sequence Identity: 22% (19 aa) LRNEEATEGDTATLWCELSKAAPVEWRKGHETLRDGDRHSLRQDGSRCELQIRGLAVVDA---GEYSCVCG--QERT--SATLTVR . .. ||.|.|| | | . |. |.| .. . |. |.| |. | ..||||. PP-VTVKEGETVTLTC-VS---QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| I-set | Obscn.AA | I-set | 3856-3939 | 32 | 2.3e-10 | 37.7 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 3856-3939 Range on HMM: 1-92/92 Sequence Identity: 32% (30 aa) ARFIEDVKNQEAREGATAVLQCELSKAAP--VEWRKGSETLRG-GDRYSLRQDG-TRCELQIHGLSVADTGEYSCV----CGQERTSATLTV .|. |..|..|| || ..|. . | |.| |. . || .||.. ..|| .. | | . .|.|.|.|| |. ..|.||| PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| I-set | Obscn.AA | I-set | 3768-3851 | 33 | 5.7e-09 | 32.95 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 3768-3851 Range on HMM: 1-92/92 Sequence Identity: 33% (31 aa) SKFIEGLRNEEATEGDTATLWCELSKAAP--VEWRKGHETLRD-GDRHSLRQDG-SRCELQIRGLAVVDAGEYSCV----CGQERTSATLTV ||. ... |..||.||.. |. . | |.| |. . || .|||. ..|| .. | |.. |.|.|.|| |. ..|.||| PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| IGc2 | Obscn.AA | IGc2 | 3868-3933 | 19 | 6.7e-07 | 30.16 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 3868-3933 Range on HMM: 1-56/56 Sequence Identity: 19% (13 aa) REGATAVLQCE--LSKAAPVEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERT .|| ...|.|. . .. . |.| .. | .. .|.| ...| |.|.|. . HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| IGc2 | Obscn.AA | IGc2 | 3780-3845 | 20 | 3.7e-05 | 24.29 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 3780-3845 Range on HMM: 1-56/56 Sequence Identity: 20% (14 aa) TEGDTATLWCE--LSKAAPVEWRKGHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEYSCVCGQERT ||...|| |. . .. . |.| . | .. .|.|. .. |.|.|.|. . HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| V-set | Obscn.AA | V-set | 3869-3939 | 15 | 0.000464 | 15.83 | Pfam | 20-128 (128) | Show / Hide |
Range on Protein: 3869-3939 Range on HMM: 20-128/128 Sequence Identity: 15% (17 aa) EGATAVLQCELS-------KAAPVEWRK-GSE-------------TLRG----------GDRYSLRQDGT--RCELQIHGLSVADTGEYSCV-----CGQ ||... |.| .| . | . .. .. .|... .... .. |.|. |...|.| | |. .. EGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNLQPSDSGTYYCAVWNCNEDY ERTSATLTV .. .||| FGHGTRLTV |
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| IGv | Obscn.AA | IGv | 3784-3928 | 11 | 0.003875 | 2.38 | SMART | 1-76 (76) | Show / Hide |
Range on Protein: 3784-3928
Range on HMM: 1-76/76
Sequence Identity: 11% (18 aa)
TATLWCELSKAAPVEWRKGHETLRDGDRHSLRQD------GSRCELQIRGLAVVDAGEYSCVCGQERTSATLTVRALPARFIEDVKNQEAREGATAVLQC
..|| |..| | .|| |.. |. ..
SVTLSCKFSGFTF-------------YMHWYRQPPDSTPKGKGLEWMGY---------------------------------------------------
ELSKAAPVEWRKGSETLRGGDRYSLRQDG------TRCELQIHGLSVADTGEYSCVC
.|... | . |....| ..||| | |
-----------------SYKGRFTWSKDNITRWSKNQFYLTMSNLRPEDTGTYYCAR
|
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| V-set | Obscn.AA | V-set | 3768-3851 | 16 | 0.01963 | 10.22 | Pfam | 1-128 (128) | Show / Hide |
Range on Protein: 3768-3851 Range on HMM: 1-128/128 Sequence Identity: 16% (21 aa) SKFIEG--LR----NEEATEGDTATLWCELS-------KAAPVEWRK-GHE-----------------------TLRDGDRHSLRQDGS--RCELQIRGL . .... | .. ||...|| | .| . | . . . | .| .. ...| .. |.|. | QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNL AVVDAGEYSCV-----CGQERTSATLTV . | | | |. .. .. .||| QPSDSGTYYCAVWNCNEDYFGHGTRLTV |
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| IG | Obscn.AA | IG | 3950-4028 | 22 | 3.5e-12 | 47.72 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 3950-4028 Range on HMM: 1-58/58 Sequence Identity: 22% (19 aa) LKTKEASEGATATLQCELSKVAPVEWKKGPETLRDGGRYSLKQDGTRCELQIHDLSVADA---GEYSCMCG--QERT--SATLTVR . ...|| |.||.| | . |. |.| .....|. |.| |. | ..||||. PP-VTVKEGETVTLTC-VS---QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| I-set | Obscn.AA | I-set | 3944-4027 | 32 | 3.3e-11 | 40.55 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 3944-4027 Range on HMM: 1-92/92 Sequence Identity: 32% (30 aa) ARFTQDLKTKEASEGATATLQCELSKVAP--VEWKKGPETLRD-GGRYSLKQDG-TRCELQIHDLSVADAGEYSC----MCGQERTSATLTV .||| .| |..|| ||...|. . | |.|.|. . || . |.. ..|| .. | | . .|.|.|.| |. ..|.||| PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| V-set | Obscn.AA | V-set | 3943-4027 | 17 | 1.2e-08 | 31.68 | Pfam | 1-128 (128) | Show / Hide |
Range on Protein: 3943-4027 Range on HMM: 1-128/128 Sequence Identity: 17% (23 aa) PARFTQ-DLK----TKEASEGATATLQCELS-------KVAPVEWKK-GPE-----------------------TLRDGGRYSLKQDGT--RCELQIHDL . || . . ...||...||.| .| . . | . .| . | ||... .... .. |.|..| QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNL SVADAGEYSCM-----CGQERTSATLTV ...| | | | .. .. .||| QPSDSGTYYCAVWNCNEDYFGHGTRLTV |
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| IGc2 | Obscn.AA | IGc2 | 3956-4021 | 20 | 1.3e-07 | 32.56 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 3956-4021 Range on HMM: 1-56/56 Sequence Identity: 20% (14 aa) SEGATATLQCE--LSKVAPVEWKKGPETLRDGGRYSLKQDGTRCELQIHDLSVADAGEYSCMCGQERT || ..||.|. . .. . |.| . | .. .|.| . ...|.|.|.| . HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| IGv | Obscn.AA | IGv | 3960-4016 | 20 | 0.005833 | 0.6 | SMART | 1-76 (76) | Show / Hide |
Range on Protein: 3960-4016 Range on HMM: 1-76/76 Sequence Identity: 20% (16 aa) TATLQCELS---------KVAP--------VEWKKGPETLRDGGRYSLKQDG------TRCELQIHDLSVADAGEYSCMC ..||.|..| . .| .|| . ||.... | . |....| ..| | | | SVTLSCKFSGFTFYMHWYRQPPDSTPKGKGLEWMGY----SYKGRFTWSKDNITRWSKNQFYLTMSNLRPEDTGTYYCAR |
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| IG | Obscn.AA | IG | 4038-4116 | 22 | 1.2e-10 | 42.58 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 4038-4116 Range on HMM: 1-58/58 Sequence Identity: 22% (19 aa) LRNEEAMEGATATLQCELSKAAPVEWRKGLEALRDGDKYSLRQDGAVCELQIHGLAMADN---GVYSCVCG--QERT--SATLTVR . ...|| |.||.| | . |. |.| .. ..| |.| |. | ..||||. PP-VTVKEGETVTLTC-VS---QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| I-set | Obscn.AA | I-set | 4032-4115 | 31 | 1e-08 | 32.08 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 4032-4115 Range on HMM: 1-92/92 Sequence Identity: 31% (29 aa) ARFTEGLRNEEAMEGATATLQCELSKAAP--VEWRKGLEALRD-GDKYSLRQDG-AVCELQIHGLAMADNGVYSCV----CGQERTSATLTV .|| ... |..|| ||...|. . | |.| |. . || .|... ..|| . | | . .| |.|.|| |. ..|.||| PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| IGc2 | Obscn.AA | IGc2 | 4044-4109 | 20 | 5.8e-05 | 22.44 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 4044-4109 Range on HMM: 1-56/56 Sequence Identity: 20% (14 aa) MEGATATLQCE--LSKAAPVEWRKGLEALRDGDKYSLRQDGAVCELQIHGLAMADNGVYSCVCGQERT || ..||.|. . .. . |.| . | .|.| ...| |.|.|. . HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| V-set | Obscn.AA | V-set | 4032-4115 | 14 | 0.013507 | 10.78 | Pfam | 1-128 (128) | Show / Hide |
Range on Protein: 4032-4115 Range on HMM: 1-128/128 Sequence Identity: 14% (19 aa) ARFTEG--LR----NEEAMEGATATLQCELS-------KAAPVEWRK-GLE-----------------------ALRDGDKYSLRQDGA--VCELQIHGL . . .. | .. ||...||.| .| . | . . | ..... ... . |.|. | QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNL AMADNGVYSCV-----CGQERTSATLTV ..|.|.| |. .. .. .||| QPSDSGTYYCAVWNCNEDYFGHGTRLTV |
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| IG | Obscn.AA | IG | 4214-4292 | 22 | 3.7e-11 | 44.33 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 4214-4292 Range on HMM: 1-58/58 Sequence Identity: 22% (19 aa) VRNHEATEGATAVLQCELSKAAPVEWRKGSETLRDGDRYSLRQDGTRCELQIRGLAVEDT---GEYLCVCG--QERT--SATLTVR . ... || |..|.| | . |. |.| .. .||. |.| |. | ..||||. PP-VTVKEGETVTLTC-VS---QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| IG | Obscn.AA | IG | 4126-4204 | 22 | 1.1e-10 | 42.78 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 4126-4204 Range on HMM: 1-58/58 Sequence Identity: 22% (19 aa) MRNQKATEGATVTLQCKLRKAAPVEWRKGPNTLKDGDRYSLKQDGTSCELQIRGLVIADA---GEYSCICE--QERT--SATLTVR . . . || ||||.| . |. |.| .. .|. |.| | . | ..||||. PP-VTVKEGETVTLTC-VS---QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| I-set | Obscn.AA | I-set | 4208-4291 | 31 | 2.2e-09 | 34.37 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 4208-4291 Range on HMM: 1-92/92 Sequence Identity: 31% (29 aa) ARFIEDVRNHEATEGATAVLQCELSKAAP--VEWRKGSETLRD-GDRYSLRQDG-TRCELQIRGLAVEDTGEYLCV----CGQERTSATLTV .|. .. |..|| || ..|. . | |.| |. . || .||.. ..|| .. | |.. .|.|.| || |. ..|.||| PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| IGc2 | Obscn.AA | IGc2 | 4132-4197 | 22 | 4.9e-08 | 33.93 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 4132-4197 Range on HMM: 1-56/56 Sequence Identity: 22% (15 aa) TEGATVTLQCK--LRKAAPVEWRKGPNTLKDGDRYSLKQDGTSCELQIRGLVIADAGEYSCICEQERT || .|||.|. . .. . |.| | .. .|.|. .|.|.|.|. . . HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| IGc2 | Obscn.AA | IGc2 | 4220-4285 | 20 | 5e-07 | 30.59 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 4220-4285 Range on HMM: 1-56/56 Sequence Identity: 20% (14 aa) TEGATAVLQCE--LSKAAPVEWRKGSETLRDGDRYSLRQDGTRCELQIRGLAVEDTGEYLCVCGQERT || ...|.|. . .. . |.| .. | .. .|.|. ..|| |.| |. . HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| I-set | Obscn.AA | I-set | 4120-4203 | 26 | 5.6e-07 | 26.2 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 4120-4203 Range on HMM: 1-92/92 Sequence Identity: 26% (24 aa) ARFIEDMRNQKATEGATVTLQCKLRKAAP--VEWRKGPNTLKD-GDRYSLKQDG-TSCELQIRGLVIADAGEYSCICE----QERTSATLTV .|. ......|| |....|. . | |.| |. |. .||.. ..|| . | |.. ..|.|.|.|. . . ..|.||| PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| V-set | Obscn.AA | V-set | 4218-4291 | 16 | 0.000385 | 16.11 | Pfam | 17-128 (128) | Show / Hide |
Range on Protein: 4218-4291 Range on HMM: 17-128/128 Sequence Identity: 16% (18 aa) EATEGATAVLQCELS-------KAAPVEWRK-GSE-----------------------TLRDGDRYSLRQDGT--RCELQIRGLAVEDTGEYLCV----- .. ||... |.| .| . | . .. . | .|... .... .. |.|. | ..|.| | |. TVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNLQPSDSGTYYCAVWNCN CGQERTSATLTV .. .. .||| EDYFGHGTRLTV |
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| V-set | Obscn.AA | V-set | 4131-4190 | 17 | 0.00044 | 15.91 | Pfam | 18-110 (128) | Show / Hide |
Range on Protein: 4131-4190 Range on HMM: 18-110/128 Sequence Identity: 17% (16 aa) ATEGATVTLQCKLR-------KAAPVEWRK-GPN-----------------------TLKDGDRYSLKQDGT--SCELQIRGLVIADAGEYSC . ||..|||.|... . | . .| . .|... .... .. |.|. | .| | | | VQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNLQPSDSGTYYC |
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| IGv | Obscn.AA | IGv | 4136-4280 | 11 | 0.003399 | 2.95 | SMART | 1-76 (76) | Show / Hide |
Range on Protein: 4136-4280
Range on HMM: 1-76/76
Sequence Identity: 11% (18 aa)
TVTLQCKLRKAAPVEWRKGPNTLKDGDRYSLKQD------GTSCELQIRGLVIADAGEYSCICEQERTSATLTVRALPARFIEDVRNHEATEGATAVLQC
.|||.||. . ..| | |. ..
SVTLSCKFSGFTF-------------YMHWYRQPPDSTPKGKGLEWMGY---------------------------------------------------
ELSKAAPVEWRKGSETLRDGDRYSLRQDG------TRCELQIRGLAVEDTGEYLCVC
.|... | . |....| .|||| | |
-----------------SYKGRFTWSKDNITRWSKNQFYLTMSNLRPEDTGTYYCAR
|
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| IG | Obscn.AA | IG | 4390-4468 | 20 | 1.1e-11 | 46.1 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 4390-4468 Range on HMM: 1-58/58 Sequence Identity: 20% (18 aa) LRNEEATEGATAMLQCELSKVAPVEWRKGPETLRDGDRYNLRQDGTRCELQIHGLSVADT---GEYSCVCG--QEKT--SATLTVK . .. || |. |.| | . |. |.| .....|. |.| |. | . ..||||. PP-VTVKEGETVTLTC-VS---QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| IG | Obscn.AA | IG | 4302-4380 | 20 | 1.9e-11 | 45.29 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 4302-4380 Range on HMM: 1-58/58 Sequence Identity: 20% (18 aa) MTNQEAREGATATLHCELSKVAPVEWRKGPETLRDGDRHSLRQDGTRCELQIRGLSVADA---GEYSCVCG--QERT--SATLTIR ....|| |.||.| | . |. |.| .....|. |.| |. | ..|||.. PP-VTVKEGETVTLTC-VS---QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| I-set | Obscn.AA | I-set | 4384-4467 | 33 | 5.6e-11 | 39.76 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 4384-4467 Range on HMM: 1-92/92 Sequence Identity: 33% (31 aa) AKFTKGLRNEEATEGATAMLQCELSKVAP--VEWRKGPETLRD-GDRYNLRQDG-TRCELQIHGLSVADTGEYSCV----CGQEKTSATLTV |||. ... |..|| || ..|. . | |.| |. . || .||.. ..|| .. | | . .|.|.|.|| |. ...|.||| PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| I-set | Obscn.AA | I-set | 4296-4379 | 31 | 1e-08 | 32.08 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 4296-4379 Range on HMM: 1-92/92 Sequence Identity: 31% (29 aa) ARFIDNMTNQEAREGATATLHCELSKVAP--VEWRKGPETLRD-GDRHSLRQDG-TRCELQIRGLSVADAGEYSCV----CGQERTSATLTI .|. ...|..|| ||.. |. . | |.| |. . || .|||. ..|| .. | |.. .|.|.|.|| |. ..|.||. PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| IGc2 | Obscn.AA | IGc2 | 4308-4373 | 20 | 3.7e-08 | 34.34 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 4308-4373 Range on HMM: 1-56/56 Sequence Identity: 20% (14 aa) REGATATLHCE--LSKVAPVEWRKGPETLRDGDRHSLRQDGTRCELQIRGLSVADAGEYSCVCGQERT .|| ..|| |. . .. . |.| . | .. .|.|. ...|.|.|.|. . HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| IGc2 | Obscn.AA | IGc2 | 4396-4461 | 19 | 3e-06 | 28.22 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 4396-4461 Range on HMM: 1-56/56 Sequence Identity: 19% (13 aa) TEGATAMLQCE--LSKVAPVEWRKGPETLRDGDRYNLRQDGTRCELQIHGLSVADTGEYSCVCGQEKT || .. |.|. . .. . |.| . | .. .|.| ...| |.|.|. .. HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| V-set | Obscn.AA | V-set | 4309-4367 | 18 | 9e-06 | 21.8 | Pfam | 20-111 (128) | Show / Hide |
Range on Protein: 4309-4367 Range on HMM: 20-111/128 Sequence Identity: 18% (17 aa) EGATATLHCELS-------KVAPVEWRK-GPE-----------------------TLRDGDRHSLRQDGT--RCELQIRGLSVADAGEYSCV ||...||.| .| . . | . .| . | .| .. .... .. |.|. |...| | | |. EGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNLQPSDSGTYYCA |
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| V-set | Obscn.AA | V-set | 4383-4467 | 16 | 9e-06 | 21.76 | Pfam | 1-128 (128) | Show / Hide |
Range on Protein: 4383-4467 Range on HMM: 1-128/128 Sequence Identity: 16% (21 aa) PAKFTK-GLR----NEEATEGATAMLQCELS-------KVAPVEWRK-GPE-----------------------TLRDGDRYNLRQDGT--RCELQIHGL . | | .. ||... |.| .| . . | . .| . | .|. . .... .. |.|. | QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNL SVADTGEYSCV-----CGQEKTSATLTV ...|.| | |. .. .. .||| QPSDSGTYYCAVWNCNEDYFGHGTRLTV |
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| IGv | Obscn.AA | IGv | 4312-4456 | 11 | 0.001304 | 7.12 | SMART | 1-76 (76) | Show / Hide |
Range on Protein: 4312-4456
Range on HMM: 1-76/76
Sequence Identity: 11% (18 aa)
TATLHCELSKVAPVEWRKGPETLRDGDRHSLRQD------GTRCELQIRGLSVADAGEYSCVCGQERTSATLTIRALPAKFTKGLRNEEATEGATAMLQC
..|| |..| | .|| | . |. ..
SVTLSCKFSGFTF-------------YMHWYRQPPDSTPKGKGLEWMGY---------------------------------------------------
ELSKVAPVEWRKGPETLRDGDRYNLRQDG------TRCELQIHGLSVADTGEYSCVC
.|... | . |....| ..||| | |
-----------------SYKGRFTWSKDNITRWSKNQFYLTMSNLRPEDTGTYYCAR
|
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| I-set | Obscn.AA | I-set | 4472-4556 | 30 | 1.6e-13 | 48.37 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 4472-4556 Range on HMM: 1-92/92 Sequence Identity: 30% (28 aa) PVFREPLQSLQAEEGSTATLQCELS-EPTATVVWSKGGLQLQA-NGRREPRLQG-CTAELVLQDLQREDTGEYTCT----CGSQATSATLTV |.| ....... ||.||...|. . .|. .|.| |.| .|. . | . | |. | .. |..|.|.|||. |.. ..|.||| PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| IG | Obscn.AA | IG | 4478-4557 | 21 | 3.3e-13 | 51.11 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 4478-4557 Range on HMM: 1-58/58 Sequence Identity: 21% (19 aa) LQSLQAEEGSTATLQCELSEPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDT---GEYTCTCG--SQAT--SATLTVT . . . ||.|.||.| | .. |. |.. ..|.||. |.|.|. .. ..||||. PP-VTVKEGETVTLTC-VS----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| IGc2 | Obscn.AA | IGc2 | 4484-4550 | 25 | 1e-10 | 42.83 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 4484-4550 Range on HMM: 1-56/56 Sequence Identity: 25% (17 aa) EEGSTATLQCE-LSEPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGEYTCTCGSQAT .|| ..||.|. |.... | | | .|. .| ... ..|| |.|||. . . HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| V-set | Obscn.AA | V-set | 4470-4556 | 17 | 4.4e-08 | 29.72 | Pfam | 1-128 (128) | Show / Hide |
Range on Protein: 4470-4556 Range on HMM: 1-128/128 Sequence Identity: 17% (23 aa) PQPVFREPLQ----SLQAEEGSTATLQCELS----EPTAT--VVWSK-GGL------------QLQAN---GRREPRLQ----------GCTAELVLQDL ...| .| .. ..|| ..||.| .| ..... . |.. . . .. .| |. .|| . .... | ...| QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNL QREDTGEYTCTCGS-----QATSATLTV |..|.| |.| . .. .||| QPSDSGTYYCAVWNCNEDYFGHGTRLTV |
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| IGv | Obscn.AA | IGv | 4488-4545 | 22 | 0.003454 | 2.88 | SMART | 1-76 (76) | Show / Hide |
Range on Protein: 4488-4545 Range on HMM: 1-76/76 Sequence Identity: 22% (17 aa) TATLQCELSEPTATVVWSKG---------GLQLQANGRREPRLQGCT----------AELVLQDLQREDTGEYTCTC ..||.|..| | .. | . || . . |... . |....|. |||| |.| SVTLSCKFSGFTFYMHWYRQPPDSTPKGKGLEWMGY-SYKGRFTWSKDNITRWSKNQFYLTMSNLRPEDTGTYYCAR |
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| IG | Obscn.AA | IG | 4567-4648 | 20 | 4.1e-08 | 34.19 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 4567-4648 Range on HMM: 1-58/58 Sequence Identity: 20% (18 aa) LQHQEVDEGGTAHLCCELSRAGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDA---GDYTCDTGHTQSMA--SLSVRVP . ..| ||.|. | | | .. |. | . .|. ||. |.|.| | | . . ..| PP-VTVKEGETVTLTC-VS----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| I-set | Obscn.AA | I-set | 4561-4632 | 32 | 3.5e-07 | 26.88 | Pfam | 1-75 (92) | Show / Hide |
Range on Protein: 4561-4632 Range on HMM: 1-75/92 Sequence Identity: 32% (24 aa) VRFLRELQHQEVDEGGTAHLCCELSRAGA-SVEWRKGSLQLFP-CAKYQMVQDG-AAAELLVRGVEQEDAGDYTC .|.. .. .|| || || . |. . .|.| |. .| | ..||..|| . | ...|...|.| ||| PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTC |
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| IGc2 | Obscn.AA | IGc2 | 4573-4639 | 23 | 0.000133 | 18.99 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 4573-4639 Range on HMM: 1-56/56 Sequence Identity: 23% (16 aa) DEGGTAHLCCE-LSRAGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQS ||... | |. . .... |.| | | .| .. |. ||.| ||| . . HEGQSVTLTCPATGNPDPNIHWYK--GQPLP----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| V-set | Obscn.AA | V-set | 4571-4645 | 12 | 0.134278 | 7.34 | Pfam | 17-128 (128) | Show / Hide |
Range on Protein: 4571-4645
Range on HMM: 17-128/128
Sequence Identity: 12% (14 aa)
EVDEGGTAHLCCELS-RA----GA-SVEWRK-GSL------------QLFPC-----------AKYQMVQDGA--AAELLVRGVEQEDAGDYTCDTGH--
.| ||....| | .| . .. | . ... .... .... ... . | . .. .| | |.| .
TVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNLQPSDSGTYYCAVWNCN
---TQSMASLSV
.. | |
EDYFGHGTRLTV
|
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| IG | Obscn.AA | IG | 4747-4828 | 20 | 3.7e-07 | 31.03 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 4747-4828
Range on HMM: 1-58/58
Sequence Identity: 20% (18 aa)
LVDAEVTADEDVEFSCEVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDA---GTVSFHLG--NHAS--SAQLTVR
.| . |.|...| || ..| |.. .|.|||. || .. | ...|||.
PP-VTVKEGETVTLTC-VS-----QIWWY-----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ
|
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| I-set | Obscn.AA | I-set | 4741-4811 | 25 | 5.4e-07 | 26.24 | Pfam | 1-72 (92) | Show / Hide |
Range on Protein: 4741-4811 Range on HMM: 1-72/92 Sequence Identity: 25% (18 aa) VTIVRGLVDAEVTADEDVEFSCEVSRAGATGVQWCLQGLPLQS-NEVTEVAVRDGRIHTLRLKGVTPEDAGT .... . |.||. |...|.|.|. |.| | ||.. .. . ... ..||. ..|.|.|.|. PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGK |
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| I-set | Obscn.AA | I-set | 4650-4736 | 30 | 2e-06 | 24.43 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 4650-4736 Range on HMM: 1-92/92 Sequence Identity: 30% (29 aa) PKFKTRLQSLEQETGDIARLCCQLSDAESGA---VVQWLKEGVELHA-GPKYEMRSQG-ATRELLIHQLEAKDTGEYACV----TGGQKTAASLRV ||| ......| |. ||. || .| .|.|.| | .|. . .. |. | | | | . .. |.|.| || | ... |.| | PKFTQKPKDVEVQEGETARFECQV----TGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| IG | Obscn.AA | IG | 4656-4737 | 16 | 1.9e-05 | 25.34 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 4656-4737 Range on HMM: 1-58/58 Sequence Identity: 16% (15 aa) LQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDT---GEYACVTG-GQKTA---ASLRVT . .. |. ..| | | ..|. | | .... |. |.| |. ||... . |.|. PP-VTVKEGETVTLTC-VS------QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| IGc2 | Obscn.AA | IGc2 | 4662-4730 | 18 | 3e-05 | 24.68 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 4662-4730 Range on HMM: 1-56/56 Sequence Identity: 18% (13 aa) ETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEYACVTGGQKT . |. ..| | .. .. ..|.| | .| .| | . | |.|.|. . . HEGQSVTLTCP-ATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| IGv | Obscn.AA | IGv | 4666-4725 | 18 | 0.00039 | 12.37 | SMART | 1-76 (76) | Show / Hide |
Range on Protein: 4666-4725 Range on HMM: 1-76/76 Sequence Identity: 18% (15 aa) IARLCCQLSDAESGAVVQWLKE---------GVELHAGPKYEMRSQGATRE----------LLIHQLEAKDTGEYACVT ..| |..| . .. |... |.|. .. .| | .. | .. |...||| | | . SVTLSCKFSGFTF--YMHWYRQPPDSTPKGKGLEWMGY-SYKGRFTWSKDNITRWSKNQFYLTMSNLRPEDTGTYYCAR |
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| IGc2 | Obscn.AA | IGc2 | 4753-4821 | 23 | 0.00076 | 11.76 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 4753-4821 Range on HMM: 1-56/56 Sequence Identity: 23% (16 aa) TADEDVEFSCEVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHAS ...|.. |... . . ..| | ||. ||..| |||||.|. . |... HEGQSVTLTCPATGNPDPNIHWYK-GQPLP------------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| V-set | Obscn.AA | V-set | 4751-4811 | 15 | 1.598557 | 3.63 | Pfam | 17-107 (128) | Show / Hide |
Range on Protein: 4751-4811 Range on HMM: 17-107/128 Sequence Identity: 15% (14 aa) EVTADEDVEFSCEVS-RA----GATGVQWCL-QGL------------------------PLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGT .| ..|...| .| . . ..|. | . | .. || . ... .|... ..|.| || TVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNLQPSDSGT |
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| V-set | Obscn.AA | V-set | 4662-4743 | 14 | 4.293579 | 2.15 | Pfam | 19-128 (128) | Show / Hide |
Range on Protein: 4662-4743
Range on HMM: 19-128/128
Sequence Identity: 14% (16 aa)
ETGDIARLCCQLS-DAES--GA-VVQWLK-EGV-----ELH---------AGPKYEMRSQGATRE-----------LLIHQLEAKDTGEYACVTGGQKTA
..|. ..| |..| | .. . ..| . ... | .| . . ... | |..|. |.| | |. .
QEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNLQPSDSGTYYCAVWNC--N
ASLRVTEPEVTI
.. ..|.
EDYFGHGTRLTV
|
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| IG | Obscn.AA | IG | 4838-4919 | 17 | 3e-06 | 28.22 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 4838-4919 Range on HMM: 1-58/58 Sequence Identity: 17% (16 aa) LQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLEDA---GTVSFHVG--TCSS--EAQLKVT . | .||......| | . .| ||. .|..||. || . . .| ...|.|. PP-VTVKEGETVTLTC-VS-----QIWWY-----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| I-set | Obscn.AA | I-set | 4832-4902 | 24 | 3.8e-05 | 19.97 | Pfam | 1-72 (92) | Show / Hide |
Range on Protein: 4832-4902 Range on HMM: 1-72/92 Sequence Identity: 24% (18 aa) VTILEPLQDVQLSEGQDASFQCRLSRASGQ---EARWALGGVPLQA-NEMNDITVEQGTLHLLTLHKVTLEDAGT ... ...||. .||..| |.| ...|. . | .| ||. .. .| ... . || .|. .|.|. PKFTQKPKDVEVQEGETARFEC---QVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGK |
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| IGc2 | Obscn.AA | IGc2 | 4844-4908 | 23 | 0.005256 | 3.72 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 4844-4908 Range on HMM: 1-56/56 Sequence Identity: 23% (16 aa) SEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLEDAG----TVSFHVG |||.....|. . . . . .| | ||. . ||. ||.||.| ... ..| HEGQSVTLTCPATGNPDPNIHWYK-GQPLP------------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| I-set | Obscn.AA | I-set | 4907-4918 | 33 | 6.536323 | 2.21 | Pfam | 81-92 (92) | Show / Hide |
Range on Protein: 4907-4918 Range on HMM: 81-92/92 Sequence Identity: 33% (4 aa) VGTCSSEAQLKV .|.....|.|.| FGEAECTAELTV |
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| IG | Obscn.AA | IG | 4928-5010 | 18 | 0.000267 | 21.53 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 4928-5010 Range on HMM: 1-58/58 Sequence Identity: 18% (17 aa) LENVEALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDS-------CRVTFLAGDMVT--SAFLTVR . |.. ||. . ..| | .|. | . |..|.|| |..| .|. .. |||. PP-VTVKEGETVTLTC-VS-----QIWWY------------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ |
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| V-set | Obscn.AA | V-set | 4922-4991 | 17 | 0.458695 | 5.5 | Pfam | 1-105 (128) | Show / Hide |
Range on Protein: 4922-4991 Range on HMM: 1-105/128 Sequence Identity: 17% (18 aa) NTVVRG--LE----NVEALEGGEALFECQLS-----------------QPEVAAHTWLL----DDEPV------HTSENAEVVFFENGL--RHLLLLKNL .| . . |.. ||. ....|..| || ...|. . .. . . . | |. |. . | ..|| QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNL RPQDS .| || QPSDS |
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| I-set | Obscn.AA | I-set | 4922-4944 | 39 | 2.207574 | 3.81 | Pfam | 1-23 (92) | Show / Hide |
Range on Protein: 4922-4944 Range on HMM: 1-23/92 Sequence Identity: 39% (9 aa) NTVVRGLENVEALEGGEALFECQ .... . .||. || | |||| PKFTQKPKDVEVQEGETARFECQ |
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| IG | Obscn.AA | IG | 5020-5102 | 15 | 0.00028 | 21.46 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 5020-5102 Range on HMM: 1-58/58 Sequence Identity: 15% (14 aa) LKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHA---GEVTFACR--DAVA--SARLTVL . |..| . .|| | . .|| | . ..|| .. |. . . . .. . ...|||. PP-VTVKEGETVTLTC-VS------QIWWY-----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ |
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| I-set | Obscn.AA | I-set | 5014-5085 | 26 | 0.000319 | 16.84 | Pfam | 1-72 (92) | Show / Hide |
Range on Protein: 5014-5085 Range on HMM: 1-72/92 Sequence Identity: 26% (19 aa) LEILEPLKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTADG-SHHALLLRSAQPHHAGE ... ..|.. |. | | |.|. . | . ||. .|. ..||.. .|.|| .. | . .|| .|. PKFTQKPKDVEVQEGETARFECQVTGD-PPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGK |
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| FN3 | Obscn.AA | FN3 | 5105-5187 | 27 | 3e-16 | 61.22 | SMART | 1-69 (69) | Show / Hide |
Range on Protein: 5105-5187 Range on HMM: 1-69/69 Sequence Identity: 27% (27 aa) PDPPED---AEVVARSSH------TVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCHELVPGPECVVDGLAPG----ETYRFRVAAV--GPVGAG |.||.. .|.. .|. .||||| .| ||| ..|.|| || .|.|||.|| . .| | PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG |
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| IG | Obscn.AA | IG | 5212-5296 | 16 | 4.3e-05 | 24.16 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 5212-5296 Range on HMM: 1-58/58 Sequence Identity: 16% (15 aa) PESRQVAAGEDVSLELEVVAEAGEVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQ---GEYHCGLAQGSICPAA-ATFQVALS |. | .||.|.|. | .. |. |.| . ..||. |.| | . . . .... . PP-VTVKEGETVTLTC-VS----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ |
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| I-set | Obscn.AA | I-set | 5212-5277 | 26 | 0.000854 | 15.39 | Pfam | 7-75 (92) | Show / Hide |
Range on Protein: 5212-5277 Range on HMM: 7-75/92 Sequence Identity: 26% (18 aa) PESRQVAAGEDVSLELEVVAE-AGEVIWHKGMERIQP-GGRFEVVSQG-RQQMLVIKGFTAEDQGEYHC | . .| ||.. .| .| . .| |.|. . ..| . |. .. | . | |.. ...| |.| | PKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTC |
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| IGc2 | Obscn.AA | IGc2 | 5218-5285 | 21 | 0.010038 | 1.03 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 5218-5285 Range on HMM: 1-56/56 Sequence Identity: 21% (15 aa) AAGEDVSLELE-VVAEAGEVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHCGLAQGSIC |..|.|. . ... .. | | .... . | || .| || |.|.| .|.... HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTC-YARNPWG |
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| V-set | Obscn.AA | V-set | 5206-5293 | 13 | 5.141539 | 1.88 | Pfam | 1-128 (128) | Show / Hide |
Range on Protein: 5206-5293 Range on HMM: 1-128/128 Sequence Identity: 13% (17 aa) PPQPSA--PE----SRQVAAGEDVSLELEVV--A----EAGEVIWHK-GME---------------RIQPGGRFEVVSQGRQQ-----M-----LVIKGF . | .. |. . |. |..|.|. . . . | . . . ...|... . .|| . | |. QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNL TAEDQGEYHCGLAQ--GSICPAAATFQV . .| | |.|. . . . .| QPSDSGTYYCAVWNCNEDYFGHGTRLTV |
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| I-set | Obscn.AA | I-set | 5480-5570 | 34 | 1.2e-22 | 79.36 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 5480-5570 Range on HMM: 1-92/92 Sequence Identity: 34% (32 aa) PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTD-GRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVV | |. . | |.|.|...|.|| | . . |.||| .|. ...|.... ||||..| |.. ...|.| |||...|.||... .| . | PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| IG | Obscn.AA | IG | 5486-5571 | 16 | 7.2e-11 | 43.35 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 5486-5571 Range on HMM: 1-58/58 Sequence Identity: 16% (15 aa) FGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADA---GCYTCQVSNKFGQVTH--SACVVVS . .....|. ..|.| |. . .|. | | .. ..|. | |.||.. ||.. .. . |. PP-VTVKEGETVTLTC-VS-----QIWWY-----------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ |
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| IGc2 | Obscn.AA | IGc2 | 5492-5560 | 24 | 2.3e-09 | 38.35 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 5492-5560 Range on HMM: 1-56/56 Sequence Identity: 24% (17 aa) QVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFG . |....|.| .. . | .|.| | .| . .| |. ..|.| |||...|. | HEGQSVTLTCPATGNPDPNIHWYK-GQPLP------------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| IQ | Obscn.AA | IQ | 5455-5475 | 47 | 2.1e-07 | 27.82 | Pfam | 1-21 (21) | Show / Hide |
Range on Protein: 5455-5475 Range on HMM: 1-21/21 Sequence Identity: 47% (10 aa) DKAAVKIQAAFKGYKVRKEMK .||.||||...||..||... HRAAIKIQAWWRGYLARKHYR |
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| IQ | Obscn.AA | IQ | 5453-5475 | 47 | 1e-06 | 29.52 | SMART | 1-23 (23) | Show / Hide |
Range on Protein: 5453-5475 Range on HMM: 1-23/23 Sequence Identity: 47% (11 aa) SMDKAAVKIQAAFKGYKVRKEMK | .||..|||.. ||..||..| RMHRAAIIIQAWWRGYLARKRYK |
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| V-set | Obscn.AA | V-set | 5424-5570 | 11 | 3.5e-05 | 19.7 | Pfam | 1-128 (128) | Show / Hide |
Range on Protein: 5424-5570
Range on HMM: 1-128/128
Sequence Identity: 11% (20 aa)
SVKPQQQQEPLAAVRPPLGDLSTKDLGDPSMDKAAVKIQAAFKGYKVRKEMKQQEGPMFSHTFGDTEAQVGDALRLECVVA-----SKADVRARWLK-DG
.. .|.... . . ..|.|. ..|.| . .... . | .
QSQVTQHPPRGC-PW-------------------------------------------------WVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQP
V-------------ELTD-----------GRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNK-FGQVTHSACVVV
.. || . . .....|| |. | ..| |.|.|.|.| ... |. ..|
PGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNLQPSDSGTYYCAVWNCNEDYFGHGTRLTV
|
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| IGv | Obscn.AA | IGv | 5496-5555 | 16 | 0.003813 | 2.45 | SMART | 1-76 (76) | Show / Hide |
Range on Protein: 5496-5555 Range on HMM: 1-76/76 Sequence Identity: 16% (13 aa) ALRLECVVASKADVRARWLKD-------GVELT------DGRHHHIDQL----GDGTCSLLITGLDRADAGCYTCQV ..| | . . |.. |..| || . .... .| ...|. .| |.|.|.. SVTLSCKFSGFTF-YMHWYRQPPDSTPKGKGLEWMGYSYKGRFTWSKDNITRWSKNQFYLTMSNLRPEDTGTYYCAR |
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| I-set | Obscn.AA | I-set | 5708-5798 | 42 | 1.3e-33 | 116.62 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 5708-5798 Range on HMM: 1-92/92 Sequence Identity: 42% (39 aa) PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEE-DDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRV |.|.. ....||| | . |.| |||.| |.| |||||. | . .|.... .|. | . |.|. | |.|.|.|.| |.|| | ....||| | PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| IGc2 | Obscn.AA | IGc2 | 5720-5788 | 31 | 3.9e-16 | 60.84 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 5720-5788 Range on HMM: 1-56/56 Sequence Identity: 31% (22 aa) QDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMG . | .|.. | .|| | |...|.| |. |. .. | |. | |.| |.|.|.|.|..| HEGQSVTLTCPATGNPDPNIHWYK-GQPLP------------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| IG | Obscn.AA | IG | 5714-5799 | 20 | 1.1e-11 | 46.13 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 5714-5799 Range on HMM: 1-58/58 Sequence Identity: 20% (18 aa) LQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADM---GVYRCLAENSMGVSS-TKAELRVD . ..|. | .|.. | |. ...|. |.| | |.| |.|.| |. .. ..| ..|.| PP-VTVKEGETVTLTC-VS-----QIWWY-----------------------LTI-NVQPEDSQQHGTYYCQAT-HGQYWSIQGTTLTVQ |
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| V-set | Obscn.AA | V-set | 5708-5798 | 14 | 2.2e-05 | 20.4 | Pfam | 1-128 (128) | Show / Hide |
Range on Protein: 5708-5798 Range on HMM: 1-128/128 Sequence Identity: 14% (19 aa) PVFLTE--LQ----NQEVQDGYPVSFDCVVTGQP----MP-SVRWFKDGKLLEEDDHYMI---------------NEDQQGGHQ-----------LIITA ....| .|| | |.. | .. . .. .. |... . . ....| . .| . | |. QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQ-QPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISN VVPADMGVYRCLAENS-MGVSSTKAELRV . |.| |.| | . |. ... . .|.| LQPSDSGTYYCAVWNCNEDYFGHGTRLTV |
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| I-set | Obscn.AA | I-set | 5842-5932 | 36 | 1.4e-20 | 72.4 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 5842-5932 Range on HMM: 1-92/92 Sequence Identity: 36% (34 aa) PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTA-SAHIRMTDKK-ILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLV |... ..|..| | . |.|. .|.|.| | ||||||||. | ...|| .. .||.| |...|.|.| . .| | | ..|.| | PKFTQKPKDVEVQEGET-ARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| IGc2 | Obscn.AA | IGc2 | 5857-5922 | 33 | 0.000136 | 18.9 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 5857-5922
Range on HMM: 1-56/56
Sequence Identity: 33% (23 aa)
TRLAKFQLK--VKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMG
..|. . |.|.| |.| |||| ||.| .||.|||| |. | .|..|
HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG
|
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| IG | Obscn.AA | IG | 5872-5933 | 23 | 0.006602 | 16.18 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 5872-5933 Range on HMM: 1-58/58 Sequence Identity: 23% (16 aa) PRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDS---GQYAAYISNAMGAAYS--SARLLVR |. .. | |...| . . . . |.| .|..||| | | . | ..| ...| |. PP-VTVKEGETVTLTC-VS--QIWWY--LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ |
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| I-set | Obscn.AA | I-set | 5953-6048 | 25 | 8.3e-19 | 66.33 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 5953-6048 Range on HMM: 1-92/92 Sequence Identity: 25% (25 aa) PRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSA-QQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHV |... . .. .|. |....|...|.| | |.| |.. ... . |. . . . . ..| ..| . |.|||.|.| .|.| |.|.| | PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRP-----DSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| IG | Obscn.AA | IG | 5959-6049 | 17 | 6.3e-11 | 43.54 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 5959-6049
Range on HMM: 1-58/58
Sequence Identity: 17% (17 aa)
FTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQ---GTYTCIASNAAGQALC--SASLHVS
|| |...|.. |. ...|. |.. .| .... |||.| |. .||. . .. |.|.
PP-VTVKEGETVTLTC-VS-----QIWWY----------------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ
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| IGc2 | Obscn.AA | IGc2 | 5965-6038 | 22 | 1.3e-08 | 35.9 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 5965-6038 Range on HMM: 1-56/56 Sequence Identity: 22% (17 aa) KKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAG . | |.|. ...|.|.|..||.. . . .| . .| . . |.|||.|.|..| HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| V-set | Obscn.AA | V-set | 5964-6048 | 16 | 5.682994 | 1.73 | Pfam | 18-128 (128) | Show / Hide |
Range on Protein: 5964-6048 Range on HMM: 18-128/128 Sequence Identity: 16% (18 aa) VKKGSSITFSVKVE-GR----PVPTVHWLR----EEAERGVL-------------WIGPDTPG-YTVASSAQ--QHSLVLLDVGRQHQGTYTCIASNA-A |. | |.|.. .. .. .. ...| | .. . . . .| .| .|.... . || . .. . . |||.| ..| VQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNLQPSDSGTYYCAVWNCNE GQALCSASLHV .. . |.| DYFGHGTRLTV |
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| RhoGEF | Obscn.AA | RhoGEF | 6279-6458 | 22 | 1.8e-28 | 99.49 | Pfam | 1-196 (196) | Show / Hide |
Range on Protein: 6279-6458 Range on HMM: 1-196/196 Sequence Identity: 22% (44 aa) VIQELLSSEQAFVEELQFLQSHHLQHLERCPHVPIAVAGQKAVIFRNVRDIGRFHSSFLQELQQ-----CD---TDDD--VAMCF--IK-NQAAFEQYLE ||||....|...|. |. . | ...|..| . || ... || |. .| .||..||..|.. | .... .. || .| . |. | | VIQEIIQTERSYVRDLNIIIEHYMKPLRNCANPPILSPDEIHTIFSNIEEIYEFHQRFLEDLEERDRMECWNPPDYQCQTIGDCFMFLKHMFPFFKMYSE FLVGRVQAESVVVSTAIQEF-YKKYAEEALLAGDPSQPPPPP-LQHYLEQPVERVQRYQALLKELIRNKAR-NRQ-NCALLEQAYAVVSALPQRAEN . .|.... . .... ... . . . . ||..| .|| |. ||. |||||... .. . |..| ... . ... YCNNYPKAMKLLKKCRKKNPKFQQFLKWCEKE-NDPCCRRLDLLQSFLIKPVQRIPRYPLLLKELLKHTPPCDHPKDYEDLQKALEAMKEVASHINE |
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| RhoGEF | Obscn.AA | RhoGEF | 6279-6458 | 21 | 1.2e-17 | 65.93 | SMART | 1-211 (211) | Show / Hide |
Range on Protein: 6279-6458 Range on HMM: 1-211/211 Sequence Identity: 21% (45 aa) VIQELLSSEQAFVEELQFLQSHHLQHLERCPH---VPIAVAGQKAVIFR-NVRDIGRFHSSFLQELQQC-------------------DTDDDVAMCFIK |||||. .|...|..|. .. | .. .... .|. .. || |. .| .||..||.|| .. | |... ||.| VIQELMQTERNYVRDLHIIVQHYMKPMQKEEKCHKLPFLSPDEVNHIFGPNIEEIYEFHRRFLDELEERIEEWDCSMDWKSFRNFQIRDICDRIGDCFMK N---QAAFEQYLEFLVGRVQAESVVVS-------TAIQEFYKKYAEEALLAGDPSQPPPPPLQHYLEQPVERVQRYQALLKELIRNKARNRQNCALLEQA . . |. | |. .|... . |.|.|. ... . | .|...| .|. |. .|. ||||.... .. |..| WFHAEEMFKMYSEYCNNHPYALKHLKKWMCCKKNPRFQKFCKECESHPNCRSN-SEH-RLTLEDFLIKPMQRITKYPLLLKEILKHTPPDHPDYEDLQKA YAVVSALPQRAEN .... ..|. . LDCMKDVAQHCNE |
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| PH | Obscn.AA | PH | 6478-6588 | 13 | 2.7e-12 | 48.11 | SMART | 1-82 (82) | Show / Hide |
Range on Protein: 6478-6588 Range on HMM: 1-82/82 Sequence Identity: 13% (15 aa) PIRQGHFIVWEGAPGARMPWKGHNRHVFLFRNHLVICKPRRDSRTDTVSYVFRNMMKLSSIDLNDQVEGDDRAFEVWQEREDSVRKYLLQARTAIIKSSW .|..|. ... . . |...||.. |...|.. . .. ||.. ... . .||.. . |..|.... . .| VIKEGWLYKKS-------K-RWKKRWFVLFNDCLYYYKDK----------KPKGSIPLSDCTVRE-P-----CFEIHH-DR----TYYFQCESEEEMQEW VKEICGIQQRL .. |. .... MQAIQKAIHNN |
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| PH | Obscn.AA | PH | 6478-6586 | 16 | 1.3e-09 | 37.37 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 6478-6586 Range on HMM: 1-92/92 Sequence Identity: 16% (18 aa) PIRQGHFIVWEGAPGARMPWKGHNRHVFLFRNHLVICKPRRDSRTDTVSYVFRNMMKLSSIDLNDQVEG-DDRAFEVWQEREDSVRKYLLQARTAIIKSS .|..|.. ... . . |...||.|.|...|.. | . . ||.... . ... .. |... . |.|..|| .. . . VIKEGWLHKKG------KRKSWKKRWFVLFNNCLYYYKDDK--------YRPKGSIPLSDCQVTKVPDNKRPHCFQIRT-DR---RTYYFQAESEEEMND WVKEICGIQQ |.. |. .. WMQAIQSACR |
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| I-set | Obscn.AA | I-set | 6690-6781 | 34 | 5.6e-22 | 77.09 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 6690-6781 Range on HMM: 1-92/92 Sequence Identity: 34% (32 aa) PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTT-GNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRI |.|. | . |||.| |.|...| | ||. |.|||. |.. ....| . .| | |. . ..| | |.| .|..|.| ..||| . PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDG-DGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| I-set | Obscn.AA | I-set | 6596-6669 | 34 | 1.6e-20 | 72.15 | Pfam | 1-75 (92) | Show / Hide |
Range on Protein: 6596-6669 Range on HMM: 1-75/92 Sequence Identity: 34% (26 aa) PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQV-DPHHILIEDPDGSCALILDSLTGVDSGQYMC | |. . | .. |||... |.|||.|.|..||.|||. ... . .| .| || . |. . . |.|.| | PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTC |
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| IGc2 | Obscn.AA | IGc2 | 6608-6676 | 31 | 1.3e-14 | 55.74 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 6608-6676 Range on HMM: 1-56/56 Sequence Identity: 31% (22 aa) ELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAG . |..| | |..|| | | |.||| |. .. .. | . . | ||| | |.| ...| HEGQSVTLTCPATGNPDPNIHWYK-GQPLP------------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| IGc2 | Obscn.AA | IGc2 | 6702-6771 | 31 | 2.7e-14 | 54.74 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 6702-6771 Range on HMM: 1-56/56 Sequence Identity: 31% (22 aa) VEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLG ||.....|| .|.| |.|.||| | | . | |. ...|| |.|.|. |. | HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-------------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| IG | Obscn.AA | IG | 6696-6782 | 20 | 3.2e-11 | 44.54 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 6696-6782 Range on HMM: 1-58/58 Sequence Identity: 20% (19 aa) VRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDL---GLYECELVNRLGSARA--SAELRIQ . .|||....|| .. ||.|| |.| ...|| | | |. |.. . ...|..| PP-VTVKEGETVTLTC-VS-----QIWWY------------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ |
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| IG | Obscn.AA | IG | 6602-6689 | 20 | 2e-08 | 35.21 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 6602-6689
Range on HMM: 1-58/58
Sequence Identity: 20% (19 aa)
LADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDS---GQYMCFAASAAGNCSTLG--KILVQVP
|. .||||.| | |. |.|| |.. ... || | | | | . .. . . ..|
PP-VTVKEGETVTLTC-VS-----QIWWY-----------------------LTI-NVQPEDSQQHGTYYCQAT----HGQYWSIQGTTLTVQ
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| IGv | Obscn.AA | IGv | 6612-6671 | 19 | 0.000241 | 14.46 | SMART | 1-76 (76) | Show / Hide |
Range on Protein: 6612-6671 Range on HMM: 1-76/76 Sequence Identity: 19% (15 aa) TVKLACRVTGTPKPVISWYKD-------GKAV-----QVDPHHILIED-----PDGSCALILDSLTGVDSGQYMCFA .|.| |...| ...||. ||.. .. . | ... | . .|. |.| | |. SVTLSCKFSGFTF-YMHWYRQPPDSTPKGKGLEWMGYSYKGRFTWSKDNITRWSKNQFYLTMSNLRPEDTGTYYCAR |
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| IGv | Obscn.AA | IGv | 6706-6766 | 16 | 0.005248 | 1.06 | SMART | 1-76 (76) | Show / Hide |
Range on Protein: 6706-6766 Range on HMM: 1-76/76 Sequence Identity: 16% (13 aa) DAQFTCTIEGAPYPQIRWYKD-------GALLTT-----GNKFQTLSEP----RSGLLVLVIRAASKEDLGLYECEL .. .|. | . .. ||. | | ..|. . .. |... || | | |. SVTLSCKFSGFTF-YMHWYRQPPDSTPKGKGLEWMGYSYKGRFTWSKDNITRWSKNQFYLTMSNLRPEDTGTYYCAR |
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| V-set | Obscn.AA | V-set | 6683-6781 | 14 | 0.005448 | 12.14 | Pfam | 1-128 (128) | Show / Hide |
Range on Protein: 6683-6781 Range on HMM: 1-128/128 Sequence Identity: 14% (20 aa) KILVQV-PPR----FVNKVRASPFVEGEDAQFTCTIE-GA----PYPQIRWYK-DGA------------LLTTG-----------NKFQTLSEPRSGLLV . |.. ||| .| . .||... ..|. . . .| ||. . .... .... . |... . QSQVTQHPPRGCPWWVTV------QEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFS LVIRAASKEDLGLYECELVNR-LGSARASAELRI | |. .. .| | | | | .. .. .|.. LTISNLQPSDSGTYYCAVWNCNEDYFGHGTRLTV |
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| V-set | Obscn.AA | V-set | 6606-6631 | 25 | 0.918489 | 4.46 | Pfam | 17-47 (128) | Show / Hide |
Range on Protein: 6606-6631 Range on HMM: 17-47/128 Sequence Identity: 25% (8 aa) TAELGETVKLACRVTGTP----KP-VISWYK |...|..|.| | .. .. . |.||. TVQEGQSVTLPCHYSDDYTCWEHNFYIYWYR |
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| I-set | Obscn.AA | I-set | 6939-7028 | 41 | 5.7e-26 | 90.64 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 6939-7028 Range on HMM: 1-92/92 Sequence Identity: 41% (38 aa) PSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVD-STRLSQQQEG-TTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV |... .. ||..| | || || ..|||.|.|.|.|| .| | | . ...| ||.| . | . |.|.||| |.| .|.. |.||| | PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| IG | Obscn.AA | IG | 6945-7029 | 17 | 1.8e-10 | 42.06 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 6945-7029 Range on HMM: 1-58/58 Sequence Identity: 17% (16 aa) IEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDA---GVYTCLAQNTGGQVLC--KAELLVL . | .. |.|.... .. ...|| |.. .| |. |.|.| |. .||. . ..| |. PP-VTVKEGETVTLTC-VS-----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ |
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| IGc2 | Obscn.AA | IGc2 | 6951-7018 | 26 | 4.2e-10 | 40.82 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 6951-7018 Range on HMM: 1-56/56 Sequence Identity: 26% (18 aa) QTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGG . |...... . .|.| |...||| . .| . .| ...|. |.|.|||.|.| | HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| V-set | Obscn.AA | V-set | 6940-7028 | 14 | 1.1e-05 | 21.41 | Pfam | 1-128 (128) | Show / Hide |
Range on Protein: 6940-7028 Range on HMM: 1-128/128 Sequence Identity: 14% (19 aa) SMQVTI---E----DVQAQTGGTAQFEAIIEGDP----QP-SVTWYK-DSV-------------------------QLVDSTRLSQQQEGTTYSLVLRHV . ||| . | .|.|... .. |. .. ...||. . . .....|.. ....|| .... QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNL ASKDAGVYTCLAQNT-GGQVLCKAELLV . | |.|.| . | .. .| | QPSDSGTYYCAVWNCNEDYFGHGTRLTV |
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| Kinase | Obscn.AA | Trio | 7050-7303 | 50 | 2.8e-231 | 600.84 | In-house | 1-258 (258) | Show / Hide |
Range on Protein: 7050-7303 Range on HMM: 1-258/258 Sequence Identity: 50% (129 aa) YEVKEEIGRGVFGFVKRVQHKGNKILCAAKFIPLRSRTRAQAYRERDILAALSHPLVTGLLDQFETRKTLILILELCSSEELLDRLYRKGVVTEAEVKVY |...||||||.|..|.|..||.... |||||||.|.....|.|.|...|..|.||.|..|.|..||....|||||||...|||..|.|.|...|.|||.| YTFQEEIGRGRFSVVRRCWHKATGRTCAAKFIPYRMMDKEQVYHEYEMLQHLQHPCVCSLHDTYETPRHYILILELCDDGELLCCLMRWGSYCESEVKTY IQQLVEGLHYLHSHGVLHLDIKPSNILMVHPAR--EDIKICDFGFAQNITPA--ELQFSQYGSPEFVSPEIIQQNPVSEASDIWAMGVISYLSLTCSSPF ..|..|..||||....|||||||.|..|.|... ..|||||||.||...|. |.|..|||.|||..|||||.||||...|||..||..|..|...||| MWQMLEAVHYLHNCHILHLDIKPENMMMWHYNAGRPQIKICDFGDAQQLWPHKVEPQHHQYGNPEFMAPEIIQGNPVSYGTDIWSIGVLTYVMLSGISPF AGESDRATLLNVLEGRVSWSSPMAAHLSEDAKDFIKATLQRAPQARPSAAQCLSHPWF ..||||.|..|...|..|.......|.|..||.||...||..|..||.|..||.|||| YDESDRETCMNICRGDFSFPECYFCHVSQNAKHFICKVLQEDPWKRPCASECLQHPWF |
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| Kinase | Obscn.AA | MLCK | 7050-7303 | 37 | 5.9e-104 | 274.71 | In-house | 1-257 (257) | Show / Hide |
Range on Protein: 7050-7303 Range on HMM: 1-257/257 Sequence Identity: 37% (96 aa) YEVKEEIGRGVFGFVKRVQHKGNKILCAAKFIPL-RSRTRAQAYRERDILAALSHPLVTGLLDQFETRKTLILILELCSSEELLDRLY-RKGVVTEAEVK |...||.||| || | |.. | .. .|||||. .. .. .| .|. | || . . | ||| . ..|.|. | .||..| .. . ||.|| YQIHEELGRGKFGIVHRCIEKSTGKTWAAKFIKCRKPKDKENVKNEIEIMNQLHHPNLIQCHDAFETKNEMVMIMEYISGGELFERIVDEDFHLTEREVI VYIQQLVEGLHYLHSHGVLHLDIKPSNILMVHPAREDIKICDFGFAQNITPAEL-QFSQYGSPEFVSPEIIQQNPVSEASDIWAMGVISYLSLTCSSPFA .|. |. ||.|..|.....|||.|| ||... . .||| ||| |. . |.| .|.||||.||... ||. ..|.|..|||.|. |. |||. HYMRQICEGVHHMHWQNIVHLDLKPENIMCQTRTSHQIKIIDFGLARKYDPDEKKVKVMFGTPEFVAPEVVNYDPVGFQTDMWSVGVICYMLLSGLSPFM GESDRATLLNVLEGRVSWSSPMAAHLSEDAKDFIKATLQRAPQARPSAAQCLSHPWF |..|| |. ||.... . |..|||||. | . . |..|..|| |||. GDNDRETMNNVTSCEWDFDDECFDDISDEAKDFISRLLVKDKEKRMTAHECLQHPWL |
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| Kinase | Obscn.AA | CAMK | 7055-7303 | 20 | 9.7e-98 | 315.53 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 7055-7303
Range on HMM: 1-425/425
Sequence Identity: 20% (89 aa)
EIGRGVFGFVKRVQHKGNK------------ILCAAKFIPLR-----------------------------SRTRAQAYRERDILAALS-------HPLV
..||| || ||...|| .. .|.|.|. . ..|.. .|| .|. |. || .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
TGLLDQFE------------TRKT--------LILIL---ELCSSEEL----LDRLYRK---------------GVVTEAEVKVYIQQLVEGLHYLHSHG
|.. .| | .. ..... |.|| || .|.. .. | .||.|.. |..|.....||.|||.
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN
VLHLDIKPSNILMVHPARED---------------IKICDFGFAQNITPAELQF------------------------SQYGSPEFVS-PEIIQQ-----
. |.|.|| |||... ... |||.|||||. ..| | .| . |.||... ||....
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN
---------NPVSEASDIWAMGVISYLSLTCSSPFAGE-------------SDRATLLNVLEGRVSWSSPM---------------------AAHLSEDA
......|.|..||| | |. .|| |. .|. .. ....|. .. .|. ..|...
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH-FVSQEC
KDFIKATLQRAPQARPSAAQCLSHPWF
||.|. ||. |. |....|||.|||.
KDLIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | Obscn.AA | S_TKc | 7050-7303 | 30 | 3.9e-83 | 283.43 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 7050-7303 Range on HMM: 1-231/231 Sequence Identity: 30% (81 aa) YEVKEEIGRGVFGFVKRVQHKGNKILCAAKFIPLRSRTRAQAYRERDILAALSHPLVTGLLDQFETRKTLILILELCSS--EELLDRLYRKGV------V ||. ..||.| || |....||. . ..| | |. ...||..|| || . |.| |.. . | ...|.|. .|.|.. ..| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF TEAEVKVYIQQLVEGLHYLHSHGVLHLDIKPSNILMVHPAREDIKICDFGFAQNITPAELQFSQYGSPEFVSPEIIQQNPVSE-ASDIWAMGVISYLSLT .| ... |..|....| |.||||..| |.||.|||. . |||||||.| . .. |.|....||.. . . ..|.|. |.| | |. PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC CSSPFAGESDRATLLNVLEGRVSWSSPMAAHLSEDAKDFIKATLQRAPQARPSAAQCLS-------HPWF || . ....... |..|||||. ||. |. ||.| ..| |||| GYPPFP---QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | Obscn.AA | DAPK | 7052-7303 | 38 | 1.6e-79 | 218.6 | In-house | 1-264 (264) | Show / Hide |
Range on Protein: 7052-7303 Range on HMM: 1-264/264 Sequence Identity: 38% (102 aa) VKEEIGRGVFGFVKRVQHKGNKILCAAKFIPLRSRTRAQA---------YRERDILAALS-HPLVTGLLDQFETRKTLILILELCSSEELLDRLYR--KG ||.||| | |....|| ||||| . | |.| .| || .. || | .| . .|||. |||||. | || | . . MGEELGRGQFAVVRKCRHKSTGKHYAAKFI--KKRRRGQSRRGVCREEIEHEIAILEECRGHPNVINLHEVYETRTDVILILEYVSGGELFDYCCEDREE VVTEAEVKVYIQQLVEGLHYLHSHGVLHLDIKPSNILMVH-PARE-DIKICDFGFAQNITPAELQFSQYGSPEFVSPEIIQQNPVSEASDIWAMGVISYL ..|... ..| ||.||||| . |||.|| ||. . ||||.||| . | ..| | ||.| |||.. | | | |.|. ||| | CLCEEDATRFMKQILEGVHYLHSRNICHLDLKPQNIMLTDRNIPQGDIKIIDFGLSRKICNGEEFRDIMGTPEYVAPEIVNYEPLSLATDMWSIGVITYI SLTCSSPFAGESDRATLLNVLEGRVSWSSPMAAHLSEDAKDFIKATLQRAPQARPSAAQCLSHPWF |. |||.|. |.||. ... | . .|| |||||. | . |. |..|..||.||| MLSGISPFLGDTKQETFLNISQVNYDFSEEYFSCTSEHAKDFIRRLLVKDPEKRMTAEECLQHPWI |
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| Kinase | Obscn.AA | Pkinase | 7050-7303 | 29 | 5.9e-73 | 253.49 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 7050-7303 Range on HMM: 1-293/293 Sequence Identity: 29% (88 aa) YEVKEEIGRGVFGFVKRVQHKGNKILCAAKFIPLRSRTRAQAYR-----ERDILAALSHPLVTGLLDQFETRKTLILILELCSSE----ELLDRLY--RK |.... ||.| || |.. .|||. .. | | |..|.. . .. | |.. |.|| . |.| ||... . ...|.| .| |.. |. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH GVV--TEAEVKVYIQQLVEGLHYLHSHGVLHLDIKPSNILMVHPAREDI----KICDFGFAQN--ITPAELQFSQYGSPEFVSPEIIQ-QNPVSEASDIW |.. .| |.| |. |...|| |.||.|..| |.||.|||.. . .| ||||||.| . . . . |.|....||.|. ... . ..|.| GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID--NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW AMGVISYLSLTCSSPFAGE------SDRATLLNVLEGRVSWSSPMAAHLS-----------------EDAKDFIKATLQRAPQARPSAAQCLSHPWF ..|.| | |. || |. .... . ...........| | |..||||| |.. |. ||.|.|.| |||| SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | Obscn.AA | DRAK | 7052-7303 | 35 | 3.1e-65 | 201.48 | In-house | 1-259 (259) | Show / Hide |
Range on Protein: 7052-7303 Range on HMM: 1-259/259 Sequence Identity: 35% (93 aa) VKEEIGRGVFGFVKRVQHKGNKILCAAKFIPLRSRTRAQAYRERDIL-------AALSHPLVTGLLDQFETRKTLILILELCSSEELLD--RLYRKGVVT | ||| | | . || |||| .. | |.| |. .|| . . | | .| . .||| .||.||. . |. . . . .. TAKERGRGKFAVVRKCIHKNTGQHFAAKF--MKKRRRGQDCRM-EILHEIAVLMLCQDCPWVINLHEVYETRSEMILVLEYAAGGEIFQYCVADKEECFC EAEVKVYIQQLVEGLHYLHSHGVLHLDIKPSNILMV-HPAREDIKICDFGFAQNITPAELQFSQYGSPEFVSPEIIQQNPVSEASDIWAMGVISYLSLTC |..|. ..| ||.||||. . ||| || |||. .|||||||| . | .| | |..| ||| . .|.. | |.| ||. |. || EKDVQRCMRQILEGVHYLHQRNIVHLDLKPQNILLTSEYPEDDIKICDFGMSRYICNGEEVREIMGTPDYVAPEILNYDPITMATDMWSIGVLTYVMLTH SSPFAGESDRATLLNVLEGRVSWSSPMAAHLSEDAKDFIKATLQRAPQARPSAAQCLSHPWF |||.|. | ||. ...| | .|. | |||. . | |..| .||.||| ISPFVGDDKQETFLNISQCNLDYSEEMFSCHSPVAIDFIQSLCVIKPEDRMTAEECLDHPWL |
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| Kinase | Obscn.AA | Ciliate-E2 | 7050-7303 | 19 | 5.7e-61 | 208.04 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 7050-7303 Range on HMM: 1-365/365 Sequence Identity: 19% (76 aa) YEVKEEIGRGVFGFVKRVQHKGNKIL------------------CAAKF--------IPLRSRTRAQAYR-----------ERDILAALSHPLVTGLLDQ |.. . ||.| || |...... .. . ...|. ... . . |. || |.|| . . . YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC FE--TRKTLILILELCSSEELLDRLY------------RKGVVTEAEVKVYIQQLVE---------------GLHYLHSHG-VLHLDIKPSNILMVHPAR |. ..... |..|.|. .|.|... . || |.| ...|... .|.|||| . ..| ||||.|||. FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----- EDIKICDFGFAQNITPA--------------------------------ELQFSQYGSPEFVSPEIIQ---------QNPVSEASDIWAMGVISYLSLTC |||.|||....... .......|.|....|||.. |.. ....|||..||| | |. --IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG SSPFAGESDRATLLNVLEGRVSWSSP--------------MAAHLSEDAKDFIKA----TLQRAPQARPS-AAQCLSHPWF || . . ... .. ..| ..|...||.|| ||. |. |.. . |.| |||| KPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | Obscn.AA | CAMKL | 7050-7303 | 28 | 8.9e-61 | 192.62 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 7050-7303 Range on HMM: 1-297/297 Sequence Identity: 28% (86 aa) YEVKEEIGRGVFGFVKRVQHKGN-KILCAAKFIPLRSRTRAQAYR----------------ERDILAALS---HPLVTGLLDQFETRKT------LILIL |.. ...|.| || || .|. . .. | |.| . . . . | |. |. || . |.. .||... . |.. YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM ELCSSEE--LLDRLYRK----GVVTEAEVKVYIQQLVEGLHYLHSHGVLHLDIKPSNILMVHPAREDIKICDFGFAQNITP-----AELQFSQYGSPEFV |.||. | |.|.. .. | .| | . | .|.|....|.||||. | |||| ||| . .. |||.||||. ..| .. . |||.. EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM SPEIIQQ-NP--VSEASDIWAMGVISYLSLTCSSPFAGESD------RATLLNVLEGRVSWSSPMAAHLSEDAKDFIKATLQRAPQARPSAAQCLSHPWF .|||.| | . |||..||| | .. || .... .| . . | |.| |..|.|. ||. | ||.. | ..|||. APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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| Kinase | Obscn.AA | RSK | 7052-7303 | 27 | 4.6e-60 | 205.87 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 7052-7303 Range on HMM: 1-278/278 Sequence Identity: 27% (77 aa) VKEE--IGRGVFGFVKRVQHKGNKILCAAKFIPLRSRTRAQ-----AYRERDILAALS-HPLVTGLLDQFETRKTLILILELCSSEELLDRLYRKGV--- .|. .| | . .....|. .. . | | . . . ..| . .||.||.. || . | . |.| . | ||.|.|. ||...|.... LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC VTEAEVKVYIQQLVEGLHYLHSHGVLHLDIKPSNILMVHPA-REDIKICDFGFAQN--ITPAELQFSQYGSPEFVSPEIIQ---QNP-VSEASDIWAMGV .| |...|. ..| . .||..|. | |.||.||| . .. ||..||||. . .. . .. |.. ||.. |. ..| |.| || FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV ISYLSLTCSSPFAG---ESDRATLLNVLEGRVSWSSPMAAHLSEDAKDFIKATLQRAPQARPS-----AAQCLSHPWF . | || .||.| .. .. ....|. | ..| . ||..|||.|.. |.| |. |.. |.. ..|||| LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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| Kinase | Obscn.AA | MARK | 7050-7303 | 29 | 1.8e-59 | 193.13 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 7050-7303 Range on HMM: 1-262/262 Sequence Identity: 29% (79 aa) YEVKEEIGRGVFGFVKRVQHKGNKILCAAKFIP---LRS-RTRAQAYRERDILAALSHPLVTGLLDQFE--TRKT-LILILELCSSEELLDRLYRK--GV |... .|| | .. || ..|| .. | |... | .. .|| .|. |.|| .. |.. .| |... . ||.|..|. ||.|... . | YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR VTEAEVKVYIQQLVEGLHYLHSHGVLHLDIKPSNILMVHPAREDIKICDFGFAQNITPAELQFSQYGSPEFVSPEIIQQNPVS-EASDIWAMGVISYLSL .| | ... .|.|....|.||... | |||| |||. . . .|||.||||. |.| .. . |.|.. .|||... | . |||..||. | . LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV TCSSPFAGES--DRATLLNVLEGRVSWSSPMAAHLSEDAKDFIKATLQRAPQARPSAAQCLSHPWF . . || | . . ..| |. . |. .| .....|. |. | ||.. ....|||. CGYFPFDGDTQDYKELYKKILRGKYD--IPCH--VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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| Kinase | Obscn.AA | RSK | 7050-7303 | 30 | 4.6e-56 | 192.57 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 7050-7303 Range on HMM: 1-271/271 Sequence Identity: 30% (83 aa) YEVKEEIGRGVFG---FVKRVQHKGNKILCAAKFIPLRSRTRA---QAYRERDILAALSHPLVTGLLDQFETRKTLILILELCSSEELLDRLYRKGVVTE ||..|.||.| |. .|..||| .. . | | | .| . .. ||.||. || . | . |.. . . .|.... .|.||| .... .| YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDRVCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFSE AEVKVYIQQLVEGLHYLHSHGVLHLDIKPSNILMVHP--AREDIKICDFGFA-QNITPAELQFSQYGSPEFVSPEIIQQNPVSEASDIWAMGVISYLSLT ||| | . . ||||.|. | | ||.||| . . ||||||||| | . .. . .. ... ||.. . ..|.|.| ||. | || REVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEMLT CSSPFAGESDRAT---LLNVLEGRVSWSSPMAAHLSEDAKDFIKATLQRAPQARPSA-----AQCLSHPWF ||.. . . .... .|. | ... . .|. ||| . . | | |. |..| .| ..|||| GCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF |
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| Kinase | Obscn.AA | TyrKc | 7050-7303 | 20 | 1.3e-12 | -18.94 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 7050-7303 Range on HMM: 1-280/280 Sequence Identity: 20% (59 aa) YEVKEEIGRGVFGFVKRVQHKGNKILCAAKFIPLRSRTRAQAYRERDILAAL--SHPLVTGLLDQFETR-------KTLILILELCSSEELLDRL-YRKG . ....|.| || | . . | | .| | . . |. .|| |. | .|| . |. . . | ...|... |.|.| .... ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP VVTEAEVKVYIQQLVEGLHYLHSHGVLHLDIKPSNILMVHPAREDIKICDFGFAQNITPA-------ELQFSQY--GSPEFV-----SPEIIQQNPVSEA .. .. . | .| ||||... | |. |.| .. .||.||| . .|. . .. |. . .|| |. . ... KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTK SDIWAMGVISY--LSLTCSSPFAG-----ESDRATLLNVLEGRVSWSSPM-----AAHLSEDAKDFIKATLQRAPQARPSAAQCLSHPWF ||.|. || . ... . .| | |.. . .| .|. | . ... . .| .. | ||. ... | | SDVWSFGVCMWEIFTY-GQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
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| Kinase | Obscn.AA | Pkinase_Tyr | 7119-7167 | 24 | 2.266787 | 1.88 | Pfam | 82-134 (270) | Show / Hide |
Range on Protein: 7119-7167 Range on HMM: 82-134/270 Sequence Identity: 24% (13 aa) LILILELCSSEELLDRLYR----KGVVTEAEVKVYIQQLVEGLHYLHSHGVLH .....|.. ||| | . |. .| . . .| .|. ||.|.. | IYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIH |
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| I-set | Obscn.AA | I-set | 8045-8130 | 34 | 5.5e-21 | 73.72 | Pfam | 1-87 (92) | Show / Hide |
Range on Protein: 8045-8130 Range on HMM: 1-87/92 Sequence Identity: 34% (30 aa) PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLES-SSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALGTVTTT |.|.. ..| .| |..... |||. .| | .| |||.|| . |.|. .... .. . |||. | ..| |.||| ..| .|....| PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECT |
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| IGc2 | Obscn.AA | IGc2 | 8057-8125 | 36 | 4.1e-13 | 50.82 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 8057-8125 Range on HMM: 1-56/56 Sequence Identity: 36% (25 aa) VLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALG |||||| | ... |... .| | | ||. . . ||| | || |.|||...|. | HEGQSVTLTCPATGNPDPNIHWYK-GQPLP------------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| IG | Obscn.AA | IG | 8051-8137 | 24 | 1.5e-09 | 39.02 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 8051-8137 Range on HMM: 1-58/58 Sequence Identity: 24% (22 aa) LSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDL---GVYTCSVSNALGTVTT-TGVLRKAE . ||..|..||| | || | .|. ||| | .|| |.|.| .. |... |. . . PP-VTVKEGETVTLTC-VS-----QIWWY-----------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ |
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| V-set | Obscn.AA | V-set | 8045-8122 | 20 | 0.000935 | 14.78 | Pfam | 1-114 (128) | Show / Hide |
Range on Protein: 8045-8122 Range on HMM: 1-114/128 Sequence Identity: 20% (23 aa) PTFLRE--LS----DETVVLGQSVTLACQVS-----AQPAAQATWSKDGAPLESSSRVLI---------------------SATLKNFQL-----LTILV . .. . ||..|||||| |..| .. . .|... |. .... .| . |. . ||| QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQ-QPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISN VVAEDLGVYTCSVSN . .| |.|.| |.| LQPSDSGTYYCAVWN |
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| IGv | Obscn.AA | IGv | 8061-8120 | 27 | 0.002796 | 3.8 | SMART | 1-76 (76) | Show / Hide |
Range on Protein: 8061-8120 Range on HMM: 1-76/76 Sequence Identity: 27% (21 aa) SVTLACQVSAQPAAQATWSKD-------GAPLE-----SSSRVLISATL-----KNFQLLTILVVVAEDLGVYTCSV |||| |..| . .| . | .|| ...|. .| || ||. . .|| |.|.|.. SVTLSCKFSGFTF-YMHWYRQPPDSTPKGKGLEWMGYSYKGRFTWSKDNITRWSKNQFYLTMSNLRPEDTGTYYCAR |
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| FN3 | Obscn.AA | FN3 | 8139-8217 | 21 | 0.000292 | 21.4 | SMART | 1-69 (69) | Show / Hide |
Range on Protein: 8139-8217 Range on HMM: 1-69/69 Sequence Identity: 21% (20 aa) PSSSPC---PDIGEVYAD------GVLLVWKPVESYGPVTYIVQCSLEGGSWTTLASDIFDCCYLTSKLSRG----GTYTFRTACVSK--AGMG |.. | . . .| .. | | ||| ||... | . |. | .|.|| ..|.. || | PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP--------IVGYR-----------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG |
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| Kinase | Obscn.AA | Trio | 8254-8506 | 48 | 1.5e-221 | 575.38 | In-house | 1-258 (258) | Show / Hide |
Range on Protein: 8254-8506 Range on HMM: 1-258/258 Sequence Identity: 48% (125 aa) FAFQTQIQRGRFSVVRQCWEKASGRALAAKIIPYHPKDKTAVLREYEALKGLRHPHLAQLHAAYLSPRHLVLILELCSGPELLPCLAERASYSESEVKDY ..||..|.||||||||.||.||.||..|||.|||...||..|..|||.|. |.||....||..|..|||..||||||...|||.||....||.|||||.| YTFQEEIGRGRFSVVRRCWHKATGRTCAAKFIPYRMMDKEQVYHEYEMLQHLQHPCVCSLHDTYETPRHYILILELCDDGELLCCLMRWGSYCESEVKTY LWQMLSATQYLHNQHILHLDLRSENMIITEYNL----LKVVDLGNAQSLSQEKVLPSDKFKDYLETMAPELLEGQGAVPQTDIWAIGVTAFIMLSAEYPV .||||.|..||||.||||||...|||....||. .|..|.|.||.|...|| |........|.||||...|......||||.|||....|||...|. MWQMLEAVHYLHNCHILHLDIKPENMMMWHYNAGRPQIKICDFGDAQQLWPHKVEPQHHQYGNPEFMAPEIIQGNPVSYGTDIWSIGVLTYVMLSGISPF SSEGARDLQRGLRKGLVRLSRCYAG-LSGGAVAFLRSTLCAQPWGRPCASSCLQCPWL ..|..|........|......||.. .|..|..|....|...||.|||||.|||.||. YDESDRETCMNICRGDFSFPECYFCHVSQNAKHFICKVLQEDPWKRPCASECLQHPWF |
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| Kinase | Obscn.AA | CAMK | 8259-8506 | 19 | 2.2e-62 | 199.54 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 8259-8506
Range on HMM: 1-425/425
Sequence Identity: 19% (82 aa)
QIQRGRFSVVRQCWEKASG------------RALAAKIIPY-----------------------------HPKDKTAVLREYEALKG-------LRHPHL
.. ||.|..|. | .| .. . |.|||. |||. |.||.| .| |.||..
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
AQLHAAYLSPRH-------------------LVLIL---ELCSGPEL----------LPC----------LAERASYSESEVKDYLWQMLSATQYLHNQH
.|. .| .|.. ..... |.||| || .| . || ..|.|.. | .|..|| .|.|...
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSHN
ILHLDLRSENMIITEY-----------------NLLKVVDLGNAQSLSQEKVLP----------------------SDKFKDYLETMA-PELLEG-----
| |.|| || ... | .|..| | |. . . . . | .| || ||.|.|
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN
---------QGAVPQTDIWAIGVTAFIMLSAEYPVSSE-------------GARDLQRGLRKGLVRLSRCYAG---------------------LSGGAV
.. |..|.|..|| .|||. ..| .. ..| . .|| . | .| .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK
AFLRSTLCAQPWGRPCASSCLQCPWL
..|. |. |. |. .. ||. ||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | Obscn.AA | MLCK | 8254-8378 | 37 | 4.6e-51 | 132.44 | In-house | 1-127 (257) | Show / Hide |
Range on Protein: 8254-8378 Range on HMM: 1-127/257 Sequence Identity: 37% (47 aa) FAFQTQIQRGRFSVVRQCWEKASGRALAAKIIPY-HPKDKTAVLREYEALKGLRHPHLAQLHAAYLSPRHLVLILELCSGPELLPCLAERA-SYSESEVK . . . . ||.|..|. | ||..|...|||.|. .|||| |..|.| .. |.|| | |.|.|. ... |.|.|. || ||. .. ..|.|| YQIHEELGRGKFGIVHRCIEKSTGKTWAAKFIKCRKPKDKENVKNEIEIMNQLHHPNLIQCHDAFETKNEMVMIMEYISGGELFERIVDEDFHLTEREVI DYLWQMLSATQYLHNQHILHLDLRSEN .|. | . . ...| |.|.||||. || HYMRQICEGVHHMHWQNIVHLDLKPEN |
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| Kinase | Obscn.AA | S_TKc | 8254-8506 | 26 | 9.9e-42 | 145.88 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 8254-8506 Range on HMM: 1-231/231 Sequence Identity: 26% (71 aa) FAFQTQIQRGRFSVVRQCWEKASGRALAAKIIPYHPKDKTAVLREYEALKGLRHPHLAQLHAAYLSPRHLVLILELCSG--PELLPCLAERAS------Y . . .| .| |..|..|..| .|| | |||. ..|| . || .||.. .|. .. . || ...|.|.| .|. . .| . . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF SESEVKDYLWQMLSATQYLHNQHILHLDLRSENMIITEYNLLKVVDLGNAQSLSQEKVLPSDKFKDY---LETMAPELLEGQGAVP-QTDIWAIGVTAFI .| ... |..|...| .|.|...|.| || || ..| .|. | | | | . . .. ||||.| | . |.|..|.. .. PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE MLSAEYPVSSEGARDLQRGLRKGLVRLSRCYAGLSGGAVAFLRSTLCAQPWGRPCASSCLQ-------CPWL ||. . | . ..|. ..| . | | |.| |. | || | .|| ||. MLCGYPPFP-----QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | Obscn.AA | Pkinase | 8254-8456 | 25 | 5.3e-36 | 128.38 | Pfam | 1-222 (293) | Show / Hide |
Range on Protein: 8254-8456 Range on HMM: 1-222/293 Sequence Identity: 25% (57 aa) FAFQTQIQRGRFSVVRQCWEKASGRALAAKIIPYHPKDKTA---VLR--EYEALKGLRHPHLAQLHAAYLSPRHLVLILELCSGP----ELLPCLA--ER . . .| .| |..|..| .| .|. | |||... ... .| | . .| |.||. .|. .. ...|. ...|.| | .| . .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH ASY--SESEVKDYLWQMLSATQYLHNQHILHLDLRSENMIIT-EYNL---LKVVDLGNAQSLSQEKVLPSDKFKDY---LETMAPELLE-GQGAVPQTDI .. || |.|.|..|.|.. .|.|.. |.| || .|| | .... .|. | | | .. .. .... .. ||||.. ||. | |. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM WAIGVTAFIMLSAEYPVSSE----GARD |..|.. ..||. . | ... . .| WSCGCILYEMLCGRPPFPGHCWHDN-HD |
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| Kinase | Obscn.AA | DAPK | 8256-8444 | 31 | 8.4e-32 | 84.63 | In-house | 1-201 (264) | Show / Hide |
Range on Protein: 8256-8444
Range on HMM: 1-201/264
Sequence Identity: 31% (65 aa)
FQTQIQRGRFSVVRQCWEKASGRALAAKIIPYHPKDKT-------AVLREYEALKGLR-HPHLAQLHAAYLSPRHLVLILELCSGPELLPCLAE--RASY
. ||.|.|||.| .| .|. ||| | . . ..| |. .| ||.. ||..| .||||. || || ..| .
MGEELGRGQFAVVRKCRHKSTGKHYAAKFIKKRRRGQSRRGVCREEIEHEIAILEECRGHPNVINLHEVYETRTDVILILEYVSGGELFDYCCEDREECL
SESEVKDYLWQMLSATQYLHNQHILHLDLRSENMIITE--YNL--LKVVDLGNAQSLSQEKVLPSDKFKDYLET---MAPELLEGQGAVPQTDIWAIGVT
.| .. . | | . ||| ..| |||| .| | . . .| .| | || |. .. |.| | ||| . . ||.|.|||
CEEDATRFMKQILEGVHYLHSRNICHLDLKPQNIMLTDRNIPQGDIKIIDFG----LSR-KICNGEEFRDIMGTPEYVAPEIVNYEPLSLATDMWSIGVI
AFIMLS
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TYIMLS
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| Kinase | Obscn.AA | Ciliate-E2 | 8254-8506 | 14 | 4.8e-31 | 103.79 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 8254-8506 Range on HMM: 1-365/365 Sequence Identity: 14% (56 aa) FAFQTQIQRGRFSVVRQCWEKASGRALAAK---------------------IIPYHPKDKTAVLREYEALKGLR----------------HPHLAQLHAA . |. .| .| |..|..| . .. | | . ...... ....| .. .. ||.. ... . YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC YL--SPRHLVLILELCSGPELLPCLAER-----------ASYSESEVKDYLWQMLS---------------ATQYLHNQH-ILHLDLRSENMIITEYNLL . . .. |..|.|.| .|. .. .. ...| |.|.. .| |. | .|||... |.| |. || .. . FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I KVVDLGNAQSLSQE------KVLPSDKFKDY-------------------------LETMAPELLEGQGAV---------PQTDIWAIGVTAFIMLSAEY |..|.|... .... |.. . .. |||| |.|.. . |||..||. ..||. .. KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP PVSSEGARDLQRGLRKGLVRLSRC---------------YAGLSGGAVAFLRS----TLCAQPWGRPC-ASSCLQCPWL | |. .. .... . .| . ... |. .| |. .. .|. ||. PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | Obscn.AA | RSK | 8254-8444 | 26 | 1.7e-26 | 94.02 | In-house | 1-207 (278) | Show / Hide |
Range on Protein: 8254-8444
Range on HMM: 1-207/278
Sequence Identity: 26% (54 aa)
FAFQTQIQRGRFSVVRQCWEKASGRALAAKIIPYHPKDKTAV-----LREYEALKGLR-HPHLAQLHAAYLSPRHLVLILELCSGPELLPCLAERAS---
.|. | ....| | ...|. | |.. . ..... ..| . |. . || . .|| |. . .| ||.|.|.|.||. | .. .
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC
YSESEVKDYLWQMLSATQYLHNQHILHLDLRSENMIITE---YNLLKVVDLGNAQSLSQEKVLPSDKFKDYLETMAPELLE----GQGAVPQTDIWAIGV
||.|...|. . .| ..|| |.| | || ||.. .. .|..| | . .. .. . ..| .| ||||.| . | . |.| ||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV
TAFIMLS
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LMYEMLT
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| Kinase | Obscn.AA | DRAK | 8257-8444 | 28 | 1.1e-24 | 73.14 | In-house | 2-196 (259) | Show / Hide |
Range on Protein: 8257-8444 Range on HMM: 2-196/259 Sequence Identity: 28% (57 aa) QTQIQRGRFSVVRQCWEKASGRALAAKIIPYHPKDKTA---VLREYEALKGLRH-PHLAQLHAAYLSPRHLVLILELCSGPELLP-CLAERA-SYSESEV . ||.| |||.| .| .|. ||| . . . .|.| | . |.. ||. | ..|.||. .| |. |.|... .| .| AKERGRGKFAVVRKCIHKNTGQHFAAKFMKKRRRGQDCRMEILHEIAVLMLCQDCPWVINLHEVYETRSEMILVLEYAAGGEIFQYCVADKEECFCEKDV KDYLWQMLSATQYLHNQHILHLDLRSENMIIT-EYNL--LKVVDLGNAQSLSQEKVLPSDKFKDYLETMAPELLEGQGAVPQTDIWAIGVTAFIMLS . . | | . .|||.. | ||||. | | || . .|..| | . . . . . .||| |. ||.| ||| ...||. QRCMRQILEGVHYLHQRNIVHLDLKPQNILLTSEYPEDDIKICDFGMSRYICNGEEV--REIMGTPDYVAPEILNYDPITMATDMWSIGVLTYVMLT |
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| Kinase | Obscn.AA | RSK | 8254-8444 | 29 | 1.4e-23 | 81.1 | In-house | 1-200 (271) | Show / Hide |
Range on Protein: 8254-8444 Range on HMM: 1-200/271 Sequence Identity: 29% (59 aa) FAFQTQIQRGRFS---VVRQCWEKASGRALAAKIIPYHPKDKT---AVLREYEALKGLRHPHLAQLHAAYLSPRHLVLILELCSGPELLPCLAERASYSE . .. | .| || |.. | |.... | ||| .| . | | || .|| .. . ... .|.... | .|. | . || YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDRVCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFSE SEVKDYLWQMLSATQYLHNQHILHLDLRSENMIITEY----NLLKVVDLGNA-QSLSQEKVLPSDKFKDYLETMAPELLEGQGAVPQTDIWAIGVTAFIM .|||.|. ..| .||| | | | || ||... . .|..|.| | |...... | . | . |||| | || |.| || ..| REVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMT--FCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEM LS |. LT |
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| Kinase | Obscn.AA | CAMKL | 8254-8393 | 24 | 2.8e-21 | 64.55 | In-house | 1-174 (297) | Show / Hide |
Range on Protein: 8254-8393 Range on HMM: 1-174/297 Sequence Identity: 24% (43 aa) FAFQTQIQRGRFSVVRQCWE-KASGRALAAKIIP-----------------YHPKDKTAVLREYEALKGLR---HPHLAQLHAAYLSPRH------LVLI . . .. .| |..|. .. . |. | ||| |..|. . ||.. .| |. ||. .|. . |.| ..|. YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV LELCSGPE--LLPCLAER----ASYSESEVKDYLWQMLSATQYLHNQHILHLDLRSENMIITEYN--LLKVVDLG .|.||| | |. . .. . .|.| . | .|..|| .|.|...| | |. || ..| . .|..| | MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFG |
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| Kinase | Obscn.AA | MARK | 8254-8378 | 28 | 7.2e-18 | 55.16 | In-house | 1-134 (262) | Show / Hide |
Range on Protein: 8254-8378 Range on HMM: 1-134/262 Sequence Identity: 28% (38 aa) FAFQTQIQRGRFSVVRQCWEKASGRALAAKIIP---YHP-KDKTAVLREYEALKGLRHPHLAQLHAAYL--SPRH-LVLILELCSGPELLPCLAER--AS . . ..| | ...|. . | .|| | ||.. . . . | || | .| | ||. .|. . ..| ..||.|..|| ||. .. .. YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR YSESEVKDYLWQMLSATQYLHNQHILHLDLRSEN .|.| . . |..|| .|.|...| | |. || LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPEN |
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| Kinase | Obscn.AA | CAMKL | 8416-8506 | 23 | 2e-08 | 22.84 | In-house | 200-297 (297) | Show / Hide |
Range on Protein: 8416-8506 Range on HMM: 200-297/297 Sequence Identity: 23% (23 aa) MAPELLEG--QGAV-PQTDIWAIGVTAFIMLSAEYP--VSSE---GARDLQRGLRKGLV-RLSRCYAGLSGGAVAFLRSTLCAQPWGRPCASSCLQCPWL ||||...| . |..|||..||. . |. ..| . |. . . ..| . . . .| . ..|. | |. || . .. ||. MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCGYYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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| Kinase | Obscn.AA | Pkinase_Tyr | 8254-8375 | 18 | 5.5e-07 | 24.28 | Pfam | 1-138 (270) | Show / Hide |
Range on Protein: 8254-8375
Range on HMM: 1-138/270
Sequence Identity: 18% (25 aa)
FAFQTQIQRGRFSVVRQCWEK----ASGRALAAKII--PYHPKD--KTAVLREYEALKGL-RHPHLAQLHAAYL-SPRH--LVLILELCSGPELLPCLAE
| .. .| | .|... | . | |.. ..... . . .|| . .| | .||.. .|... . .. . ...|.. . || | .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK
----RASYSESEVKDYLWQMLSATQYLHNQHILHLDLR
. . . .. .. || .. .||..... | ||.
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLA
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| Kinase | Obscn.AA | DRAK | 8472-8506 | 34 | 7.1e-07 | 16.79 | In-house | 225-259 (259) | Show / Hide |
Range on Protein: 8472-8506 Range on HMM: 225-259/259 Sequence Identity: 34% (12 aa) YAGLSGGAVAFLRSTLCAQPWGRPCASSCLQCPWL . ..| |. | .| . .| |. | .||. ||| FSCHSPVAIDFIQSLCVIKPEDRMTAEECLDHPWL |
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| Kinase | Obscn.AA | MARK | 8416-8506 | 23 | 3e-06 | 16.72 | In-house | 172-262 (262) | Show / Hide |
Range on Protein: 8416-8506 Range on HMM: 172-262/262 Sequence Identity: 23% (22 aa) MAPELLEGQGAV-PQTDIWAIGVTAFIMLSAEYPVSSEG--ARDLQRGLRKGLVRLSRCYAGLSGGAVAFLRSTLCAQPWGRPCASSCLQCPWL ||||..... | .|||. || ..|.. .| . .|.. ..| . |. .| .. .... | . |. || .. ... ||. MAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYD-IPCH--VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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| Kinase | Obscn.AA | MLCK | 8428-8444 | 47 | 7.3e-05 | 8.19 | In-house | 178-194 (257) | Show / Hide |
Range on Protein: 8428-8444 Range on HMM: 178-194/257 Sequence Identity: 47% (8 aa) PQTDIWAIGVTAFIMLS .|||.|..|| ....|| FQTDMWSVGVICYMLLS |
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| Kinase | Obscn.AA | DAPK | 8474-8506 | 39 | 0.000126 | 8.34 | In-house | 232-264 (264) | Show / Hide |
Range on Protein: 8474-8506 Range on HMM: 232-264/264 Sequence Identity: 39% (13 aa) GLSGGAVAFLRSTLCAQPWGRPCASSCLQCPWL ..| |. | |. | | |. | .||| ||. CTSEHAKDFIRRLLVKDPEKRMTAEECLQHPWI |
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| Kinase | Obscn.AA | MLCK | 8494-8506 | 61 | 0.028777 | 1.21 | In-house | 245-257 (257) | Show / Hide |
Range on Protein: 8494-8506 Range on HMM: 245-257/257 Sequence Identity: 61% (8 aa) RPCASSCLQCPWL |. |. ||| ||| RMTAHECLQHPWL |
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