Gene p70S6Kb (Human)

p70S6Kb

Species: Human
Alias: P70-beta-1, p70S6Kb, P70-beta-2, P70-BETA, STK14B, p70(S6K)-beta, SRK, P70S6KB, RPS6KB2, KLS, S6K2, S6K-beta2
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 11q11-q13.3,

Classification

Group: AGC
Family: RSK
Subfamily: RSKp70

Sequence

Name Sequence Type Origin Length Description Download
p70S6Kb.NA RNA Sugen Kinome 1782 None Fasta, JSON
p70S6Kb.AA Protein Sugen Kinome 482 None Fasta, JSON
p70S6Kb.kin_dom Protein Kinase Domain Sugen Kinome 262 None Fasta, JSON

Protein domain

Protein domains of p70S6Kb.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase p70S6Kb.AA p70 67-328 70 7.4e-220 736.69 In-house 1-299 (299) Show / Hide 
Range on Protein: 67-328
Range on HMM: 1-299/299
Sequence Identity: 70% (211 aa)

FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTR-------------------------AERNILESVKHPFIVELAYAFQTG
||||.||||||||||||||||.|.. |||||||||||||||||.|||||||                         |||||||.||||||..|.|||||.
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN

GKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAV----------THTFCG
||||||||.|.|||||.||||.||..||||||||.||..||.|||..|||||||||||.||..|||..||||||||||||.|||          ||||||
GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG

TIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGK--LALPPYLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFF
||||||||||.|.|||.||||||||.||||||||.||||.||||||.|||..||  |.||||||...|||.||.|||.|.||.|.||.||||.|.||||
TIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF
Kinase p70S6Kb.AA AGC 67-328 36 4.4e-195 510.16 In-house 1-395 (395) Show / Hide 
Range on Protein: 67-328
Range on HMM: 1-395/395
Sequence Identity: 36% (147 aa)

FELLRVLGKGGYGKVFQVRKVQGT---NLGKIYAMKVLRKAK-IVRNAK-DTAHTRAE------------RNILESVK----------HPFIVE-LAYAF
||.|.|.|||..|||..|||. |.     ||.||||||.|.. ||.. | . .|| .|            ||||| ..          |||||  | |.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTGGK--LYLILE----CLS-----GG-ELFTHLE---REGIFLEDTACFYLAE-------ITLALGHLHS-QGIIYRD-LKPENIMLSSQGHIKLTDFG
|.  .  ||...|     ..     || |||.||    .||.| |..|.||.||       |.||| .||| .|||.|| ||||||.| ..|||||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LCKESIHEG--------------------------------------------------AVTHTFCG--TIEYMAPEILVRSGHNRAVDWWS--LGALMY
|||| . .|                                                  . |.||||  | ||||||||    ...|.||||  ||.|||
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

DMLTGSPPFTAEN----------RKKTMDKII------RGKLALP----------PYLTPDARDLVKKFLKRNPSQRIGGGPGD-----AADVQRHPFF
 |||| |||...|          ......||.        |. .|          ....|.|.||.||.|...|..|.| |..|     | ....||.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase p70S6Kb.AA RSK 70-328 57 8.3e-177 593.67 In-house 1-278 (278) Show / Hide 
Range on Protein: 70-328
Range on HMM: 1-278/278
Sequence Identity: 57% (161 aa)

LRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVK-HPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGI---
|.|||.|||||||..||... . |.|||||||.|||||...|||.||..|||||| .. |||||.| |||||.||||||.|...||||||||..|..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSS---QGHIKLTDFGLCKE-SIHEGAVTHTFCGTIEYMAPEILV----RSGHNRAVDWWSLGA
| ||.||||.|||.||. |||.||||.||||||||.. .   .|||||||||.||. .....  |.|||.||||||||.|     ..||..|.||||||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LMYDMLTGSPPFTA---ENRKKTMDKIIRGK--LALP--PYLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFF
|||.|||| |||..   .|||..|..| .||  | .|  .||...|.||..| |.|.|..|.|.||.||.....||.|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase p70S6Kb.AA SGK 67-328 47 2.6e-152 473.97 In-house 1-283 (283) Show / Hide 
Range on Protein: 67-328
Range on HMM: 1-283/283
Sequence Identity: 47% (136 aa)

FELLRVLGKGGYGKVFQVRKVQG---------------TNLGKIYAMKVLRKAKIV------RNAKDTAHTRAER-NILESVKHPFIVELAYAFQTGGKL
|..| |.|||..|||.||....                   .|.||||||.|. |.       . |   |. ||| .||  .|||||| | |||||  ||
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRS
|. .. . |||.| || ||..|.|| | || ||| .||..|||| |||||||||||.| .|||..||||||||| | .   | ||||| ||.|||.|   
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

GHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFF
.| |.||||.||...|.|..| |||   |..   |.||...| .||. ..||.|| .  |...|..| |    |......||||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTK-RDFMEIKNHPFF
Kinase p70S6Kb.AA Akt 67-328 51 2.8e-148 477.14 In-house 1-264 (264) Show / Hide 
Range on Protein: 67-328
Range on HMM: 1-264/264
Sequence Identity: 51% (137 aa)

FELLRVLGKGGYGKVFQVRKVQGTNLGKIY-AMKVLRKAKIVRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGI
|..|.||||| .||||.|.| .    .|.| |||||.| .|. .    .|| .|||||. ..||||| | |.|||  |||....  .|||||.|| |...
FDFLKVLGKGSFGKVFLVKKKDT---QKWYYAMKVLKKDYIIQKN-QVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRR

FLEDTACFYLAEITLALGHLHSQGIIYRD-LKPENIMLSSQGHIKLTDFGLCKES-IHEGAVTHTFCGTIEYMAPEILVRSGHNRAVDWWS-LGALMYDM
| ||.| || ||| ||..||||..||||| ||||||.....|||.|||||||||  | .. .| ||||| ||.|||||   || .|||||. ||..|| |
FSEDRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEM

LTGSPPFTAENRKKTMDKIIRGKLALP--PYLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFF
..| ||| ...... ..||  ...  |  ... |...||... |...|..| ||||.|| ...|||.|
MCGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase p70S6Kb.AA RSK 67-328 42 5.9e-134 451.32 In-house 1-271 (271) Show / Hide 
Range on Protein: 67-328
Range on HMM: 1-271/271
Sequence Identity: 42% (117 aa)

FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIF
.||....|.| ..||. ..|.|.   .. ||||...||...  .||.  . .||.||. . ||||| |.|.||..||.|.|.. . ||.||..| ... |
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRD--VKDRVCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMF

LEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQ----GHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGHNRAVDWWSLGALMYDM
 |. ..||.|||.||. .||||||..|||||||| ....    ||||..|||. |... |   . |||.|..|||||.| | || .|.||||.|.||| |
SEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEM

LTGSPPFTAENRKKTMDKIIRGKLAL-------PPYLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFF
||| .|| . .|. .|..| | ||..       . .... | ||. . |.|.| .| | || ..... .||.|
LTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase p70S6Kb.AA RSK-Unclassified 67-328 43 1.9e-121 383.39 In-house 1-283 (283) Show / Hide 
Range on Protein: 67-328
Range on HMM: 1-283/283
Sequence Identity: 43% (125 aa)

FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLE--REG
|.  | .|.|  |||. ||| ..|.  .||||||| | |..|  | .     |.||.   .||||| | ..|||  .|||..|   ||..| ||   .| 
FIKHRLIGQGDFGKVYLVRK-KDTQ--QIYAMKVLHKHKMIRHNK-IKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEK

IFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKES---------------------IHEGAVTHTFCGTIEYMAPEILVR
 | || . ||..|.|.|| .|| ...|||||||.||.|   ||..||||.| ..                      . .|  |  |||| ||.|||.. |
CFCEDDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRR

SGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALP--PYLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFF
 || .||||| || .|| || | ||. ..|.  |   | .... .|   |.  ..|||.|| |.|||. | | . |||.|. |||||
CGHTKAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase p70S6Kb.AA PKA 67-328 43 1.5e-114 386.9 In-house 1-263 (263) Show / Hide 
Range on Protein: 67-328
Range on HMM: 1-263/263
Sequence Identity: 43% (117 aa)

FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHPFIV-ELAYAFQTGGKLYLILECLSGGELFTHLEREGI
||....||.| .|.| ..|. ...   ..||||.|.|..|||  | . |.  |.||| ..|||||| .. . ||.  .||...|  .|||.|..| ..| 
FEIIQTLGTGSFGRVMLCRHKHSG---NYYAMKMLKKQEIVR-LKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGR

FLEDTACFYLA-EITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRS-GHNRAVDWWSLGALMYDML
| ...|.|| | .|.|||  |||| |||||||||||.. ..||||.||||  |. . .  .| | ||| ||.||||. .. ||...||||.|| | | ||
FSNPHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKK-VDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEML

TGSPPFTAE--NRKKTMDKIIRGKLALPPYLTPDA---RDLVKKFLKRNPSQRIGGGPGDAADVQRHPFF
.| |||...  .  .. .||. ||.  |.....||   .||.|| | .....|.|   ... |. .|..|
AGYPPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase p70S6Kb.AA AktR 67-328 43 3.7e-113 382.23 In-house 1-268 (268) Show / Hide 
Range on Protein: 67-328
Range on HMM: 1-268/268
Sequence Identity: 43% (118 aa)

FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILE-SVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGI
|.....||||..|||. |.|    . .|.||||...| |  .. .   ||. ||||.|  ..||||| | |.|||  ||..|.|   |||||.|| ... 
FHVYKCLGKGAFGKVYLVQKKR--DNQKQYAMKMIKK-KKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKK

FLEDTACFYLAEITLALGHLHSQ-GIIYRDLKPENIMLSSQGHIKLTDFGLCK-ESIH-EGAVTHTFCGTIEYMAPEILVR-SGHNRAVDWWSLGALMYD
| |..| || |.| ||| .||..  |||||||||||.| . ||.|.||||| | . .  .  ....|||| ||||||.. .  |||..||||..|.. | 
FSEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYE

MLTGSPPFTAENRKKTMDKIIRGK-LALPPY--LTPDARDLVK-KFLKRNPSQRIGGGPGDAADVQRHPFF
|.|| |||...|..   .||.    .  |..  ... ..||.. | |..|| .|.| .  .. .. .||.|
MVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase p70S6Kb.AA MSK 70-323 40 2.1e-108 366.41 In-house 1-277 (277) Show / Hide 
Range on Protein: 70-323
Range on HMM: 1-277/277
Sequence Identity: 40% (111 aa)

LRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESV-KHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLE
|.|||.|||||.| .||. . . ||.||||.|.|| .|  .| ..||..|| .|| . .||.||.| ||||.  ..||..| ..|||||||. . . | |
LKVLGTGGYGKFFICRKCVHHDTGKLYAMKILSKATVVQKRKTAEHTQTERQCLEMCQQHPNIVNLHYAFQDQCHTYLVMEYCNGGELFTHIRKREHFDE

DTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQ---GHIKLTDFGLCKESIHE-GAVTHTFCGTIEYMAPEILVR-----SGHNRAVDWWSLGALM
. . ....|. .|. |.|. |||.||||||||.. ..   ||.||.|||. ..   .    ....|.|..|||||.| |     .|.. |.||||||...
SECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRGYAQDGGYDEACDWWSLGVIL

YDMLTGSPPFT--AENRK-------KTMDKIIRGKLALP----PYLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQ
| ||||  ||.  .. |.         | .| .|.  .|        |||.||... | ..|. | | .. .|  . 
YTMLTGQVPFQQNEDDRQHSCNSHHEIMKRICKGEFSFPGMAWQNMSPDAKDLIQWLLTKDPKKRLGMNDLRAHEWK
Kinase p70S6Kb.AA S_TKc 67-328 36 2.3e-108 367.25 SMART 1-231 (231) Show / Hide 
Range on Protein: 67-328
Range on HMM: 1-231/231
Sequence Identity: 36% (100 aa)

FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSG--GELFTHLEREG
.|.||..|||..|||...|..     |.|.|.|...            |.| |..||.. .||.|| | ..||. ..||...|...|  |.||..... |
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG

I------FLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGHNR-AVDWWSLGA
       | | .|.||...| .|| ..||.|||.||||||||.|..  |||..||||...        .||||| .|||||.|   |... ..||||.| 
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

LMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKRNPSQRIGGGPGDA--ADVQRHPFF
..| ||.| |||   . .....||           .|.|.|...| |...|..|..     .   |.  ||.|
ILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase p70S6Kb.AA Pkinase 67-328 29 3.7e-92 317.27 Pfam 1-293 (293) Show / Hide 
Range on Protein: 67-328
Range on HMM: 1-293/293
Sequence Identity: 29% (89 aa)

FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGG----ELFTHLE-
....|..|.|..|.|.. ...     |||.|.|...| ..  . . |.  ..|  |. ...||.||.| ..|......|...|.. ||    .||.... 
YHIGRKIGSGSFGCVYKCHHKGT---GKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

-REGIF--LEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHI----KLTDFGLCKES-IHEGAVTHTFCGTIEYMAPEILV-RSGHNRAVDW
 |.| |   |....||. .|  .| ..||.|||.||||||||.....|||    |..||||.|   .  .  ..|||||..|||||..  .... ..||.
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSLGALMYDMLTGSPPFTAE------NRKKTMDKIIRGKLALPPYLT---------------------PDARDLVKKFLKRNPSQRIGGGPGDAADVQRH
||.| ..| ||.| |||  .      . .. ...| ...|  . . .                     ....|..|. |...|..|..     |...  |
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQH

PFF
|.|
PWF
Kinase p70S6Kb.AA S_TK_X 329-391 37 5.8e-24 86.86 SMART 1-79 (79) Show / Hide 
Range on Protein: 329-391
Range on HMM: 1-79/79
Sequence Identity: 37% (30 aa)

RHMNWDDLLA--WRVDPPFRPCLQ----SEEDVSQFDTRFTRQTPVDSPDDTALSESANQA----------FLGFTYVA
|. .||.|..   .. |||.| ..    |..|.|.||. ||..||...|||..||.|..|           |.|||||.
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase p70S6Kb.AA Pkinase_C 348-393 40 1e-16 62.04 Pfam 1-46 (46) Show / Hide 
Range on Protein: 348-393
Range on HMM: 1-46/46
Sequence Identity: 40% (19 aa)

CLQSEEDVSQFDTRFTRQTPVDS-PDDTALSESANQAFLGFTYVAPS
 . |..|.| ||. ||...|.|. ||.. .|.... .| |||||.|.
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD
Kinase p70S6Kb.AA TyrKc 67-328 19 1.7e-13 -4.3 SMART 1-280 (280) Show / Hide 
Range on Protein: 67-328
Range on HMM: 1-280/280
Sequence Identity: 19% (57 aa)

FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESV--KHPFIVELAYAFQTG-------GKLYLILECLSGGELF
 .|...|| | .|.|.. .           | |.|.. .        .  . | .|. ..  .|| || |  .  ..       . |....|  ..| | 
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK

THLEREGI-FLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHE-------GAVTHTF--CGT----IEYMAPEILVR
 .| . .  .  .. . .   |     .|||...| |||   |.........| .||||...  ..          ...   .|     |  |||| .  
DYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY

SGHNRAVDWWSLGALMYDMLT-GSPPFTA-----ENRKKTMDKIIRG-KLALPPY--------LTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFF
.  . . | || | .|. ..| | .|         . .  . .. .|  .  ||.         ...  .. |.  ...|..|        ...  | .|
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDR-----PTFSEI--HECF
Kinase p70S6Kb.AA Pkinase_Tyr 121-217 23 0.000989 13.26 Pfam 55-159 (270) Show / Hide 
Range on Protein: 121-217
Range on HMM: 55-159/270
Sequence Identity: 23% (25 aa)

NILESV-KHPFIVELAYAFQ-TGGK--LYLILECLSGGELFTHLER----EGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTD
.|. .  .|| || |  .    |.   .|...|   .| | ..| .    .. .   . . . ..|  .. .|.|...| |||   |.........| .|
KIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICD

FGLCK
|||..
FGLAR
Kinase p70S6Kb.AA Pkinase_Tyr 67-83 29 0.80655 3.4 Pfam 1-17 (270) Show / Hide 
Range on Protein: 67-83
Range on HMM: 1-17/270
Sequence Identity: 29% (5 aa)

FELLRVLGKGGYGKVFQ
 .....||.| .|.|..
ITFGKKLGEGAFGEVYK