Gene PBK (Human)

PBK

Species: Human
Alias: SPK, Hs.104741, LOC55872, Nori-3, FLJ14385, TOPK, LOC55886, PBK
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 8p21.2,

Classification

Group: Other
Family: TOPK

Sequence

Name Sequence Type Origin Length Description Download
PBK.NA RNA Sugen Kinome 1899 None Fasta, JSON
PBK.AA Protein Sugen Kinome 322 None Fasta, JSON
PBK.kin_dom Protein Kinase Domain Sugen Kinome 287 None Fasta, JSON

Protein domain

Protein domains of PBK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase PBK.AA TOPK 32-318 68 1.5e-240 805.44 In-house 1-292 (292) Show / Hide 
Range on Protein: 32-318
Range on HMM: 1-292/292
Sequence Identity: 68% (200 aa)

SPFMQKLGFGTGVNVYLMKRSP-RGLSHSPWAVKKINPICNDHYRSVYQK-RLMDEAKILKSLHHPNIVGYRAFTEANDGSLCLAMEYGGEKSLNDLIEE
||.|||||.|||..||.|.||| ||..|||||||||...|.||||.|||. |||.||||||..|||||||.|||||..|||||||||..|..||.|.|||
SPMMQKLGHGTGIRVYRMDRSPRRGEIHSPWAVKKIRQNCRDHYRTVYQEGRLMHEAKILKKMHHPNIVGFRAFTENDDGSLCLAMEMCGQQSLMDMIEE

RYKASQDPFPAAIILKVALNMARGLKYLHQEKKLLHGDIKSSNVVIKGDFETIKICDVGVSLPLDENMT---VTDPEACYIGTEPWKPKEAVEENGVITD
|......|||||.|.|.|..||..|.|||.||...|||.||.||..||||||.|.||.||||||||||.   ...||.||.||.||.||..|..|||||.
RHDEDKGPFPAAHIYKMAMHMAQALDYLHNEKHYMHGDLKSFNVLVKGDFETCKLCDFGVSLPLDENMNVNFLKNPEDCYVGTQPWCPKMVVHMNGVITH

KADIFAFGLTLWEMMTLSIPHINLSNDDDDEDKTFDESDFDDEAYYAALGTRPPINMEELDESYQKVIELFSVCTNEDPKDRPSAAHIVEAL
|||.|.|||..||||||.||||||..||||||..|||.|||||.||||||||.|||||.||..||...|||..||||||.|||||.||.|||
KADMFSFGLVIWEMMTLCIPHINLPFDDDDEDYDFDETDFDDEEYYAALGTRMPINMENLDDTYQFQCELFCFCTNEDPNDRPSAMHIHEAL
Kinase PBK.AA TKL 62-318 18 6.8e-41 142.18 In-house 30-364 (364) Show / Hide 
Range on Protein: 62-318
Range on HMM: 30-364/364
Sequence Identity: 18% (67 aa)

AVKKINPIC----------------------NDHYRSVYQKRLMDEAKILKSLHHPNIVGYRAFTEANDG------------SLCLAMEYGGEKS-LNDL
||||..                         ||   | .....  |......|.||||| . ..  ....             ||. |||    | |..|
AVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYL

IEERYKASQDPFPAAIILKVALNMARGLKYLHQEKK-------LLHGDIKSSNVVIKGDFE-------------TIKICDVGVSLPLDENMTVTDPE---
.               ... || .|||. |||...        ..| |.||.|. .. ...             ..|||| | |  .....  .| .   
H------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTM

------------ACYIG-TEPWKPKEAVEEN---------------GVITDKADIFAFGLTLWEMMTLSIPHINLSNDDDDEDKTFDESDFDDEA-----
             . .. |  | . |. ...               .  . |.|...||. |||..|  .               ... .....      
MESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR--------------PYYDYPYMPMIFQDPF

----YYAAL-GTRPPINMEELD------ESYQ--KVIELFSVCTNEDPKDRPSAAHIVEAL
    ..... | ||||  . ..      ...    ...|   | ..||..|||.  |.. |
EEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase PBK.AA Pkinase 32-318 19 2.8e-30 108.13 Pfam 1-293 (293) Show / Hide 
Range on Protein: 32-318
Range on HMM: 1-293/293
Sequence Identity: 19% (65 aa)

SPFMQKLGFGTGVNVYLMKRSPRGLSHSPWAVKKINPICNDHYRSVYQKRLMDEAKILKSLHHPNIVGYRAFTEANDGSLCLAMEYGGEK----SLNDLI
  . .|.| |.   ||. ..   |     .|||.|.   ...   ..  ||  |..|.|.|.||||| .. . |  ...... ||| .      .| |.|
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYI

EERYKASQDPF--PAAIILKVALNMARGLKYLHQEKKLLHGDIKSSNVVIKGDFET---IKICDVGVS----LPLDENMTVTDPEACYIGTEPWKPKEAV
.     .. .|  .   . .... ..|||.|.|. .. .| |.|..|. |. . ..   .|||| |..    .  .. ||.      . || .. . | .
ST---WRHGCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTT------FCGTPWYMAPEVI

EENGVITDKADIFAFGLTLWEMMTLSIPHINLSNDDDDEDKTFDESDFDDE----------AYYAALGTRPPINMEELDESY-----------------Q
 ..  .. |.|....|..|.||..                    .  |...           ..  .|.... . ..... .                 .
RGGQYYGPKVDMWSCGCILYEMLC-------------------GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSE

KVIELFSVCTNEDPKDRPSAAHIVEA--L
  ... . | . |||.||.|..|..   .
ECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase PBK.AA STE 79-252 25 7.8e-28 95.43 In-house 72-273 (359) Show / Hide 
Range on Protein: 79-252
Range on HMM: 72-273/359
Sequence Identity: 25% (53 aa)

QKRLMDEAKILKSLH--HPNIVGYRAFTEAN------DGSLCLAMEYGGEKSLNDLIEERYKASQ---------DPFPAAIILKVALNMARG-LKYLHQE
..... | ||.| ..  ||||| |    . .      |..|...||| .  || |.|...|.  .         ..||  .| ...    .| |.|||. 
MQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSH

KKLLHGDIKSSNVVIKGDFETIKICDVGVSLPLDENMT------------VTDPEA-CYIGTEPWKPKEAVEE-----NGVITDKADIFAFGLTLWEMMT
.   | |||..|. .      .|.|| ||.  |...|.             .. .    .||  |   | ..      ..  . |.||  .|.|..|| |
H-IIHRDIKPANILL------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMAT

LSIPHINLSN
   |. ....
GKPPWHDMHP
Kinase PBK.AA S_TKc 32-318 20 2.6e-27 97.95 SMART 1-231 (231) Show / Hide 
Range on Protein: 32-318
Range on HMM: 1-231/231
Sequence Identity: 20% (60 aa)

SPFMQKLGFGTGVNVYLMKRSPRGLSHSPWAVKKINPICNDHYRSVYQKRLMDEAKILKSLHHPNIVGYRAFTEANDGSLCLAMEYGGE--KSLNDLIEE
  ...|.| |.   ||. .      ..   |.|.|.            .... | .|||. |||||| .  . .   ..|.. ||| .    .| |.|..
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK------------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKK

RYK-ASQDPFPAAIILKVALNMARGLKYLHQEKKLLHGDIKSSNVVIKGDFETIKICDVGVSLPLDENMTVTDPEACYIGTEPWKPKEAVEENGVITD-K
| .   . |||   . ...  ....|.|.|.  . .| |.| .|. .     .||||| |..  |            ..||  . . | .      .  |
RGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE---HIKICDFGLARQL----------TTFCGTPWYMAPEVL----GYGKCK

ADIFAFGLTLWEMMTLSIPHINLSNDDDDEDKTFDESDFDDEAYYAALGTRPPINMEELDESYQKVIELFSVCTNEDPKDRPSAAHIVE---------AL
.|. ..| .|.||..   |                    .... .  .|              . .... . | . ||..||.|  . .          .
CDWWSCGCILYEMLCGYPPFP------------------QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase PBK.AA MLK 85-242 26 9.3e-24 79.38 In-house 55-231 (291) Show / Hide 
Range on Protein: 85-242
Range on HMM: 55-231/291
Sequence Identity: 26% (48 aa)

EAKILKSLHHPN----IVGYRAFTEANDGSLCLAMEYGGEKSLNDLIEERYKASQD---------PFPAAIILKVALNMARGLKYLHQEKK--LLHGDIK
|...|. | |||    |.  ..    .   .|. |||  . ||.... .. . . |           . . ... ||..|||. |||....  . | |.|
ECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLK

SSNVVIKG-----DFETIKICDVGVSLPLDEN---MTVTDPEACYIGTEPWKPKEAVE--ENGVITDKADIFAFGLTLWEMMT
|.|..|       . .| |||| |.|  . ..   |.      . .||  |   |. .  ...  . |.|.. .|. ||||.|
SHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMM------SNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLT
Kinase PBK.AA NEK 79-190 33 4.6e-23 78.35 In-house 47-170 (286) Show / Hide 
Range on Protein: 79-190
Range on HMM: 47-170/286
Sequence Identity: 33% (41 aa)

QKRLM-DEAKILKSLHHPNIVGYR-AFTEANDGSLCLAMEYGG-EKSLNDLIEE--RYKASQDPFPAAIILKVALNMARGLKYLHQEK----KLLHGDIK
.. ..  |..|||.|.|||||.|. .| | ....||  |||   .  | ..| .  ..| . ..|.  .|...   |. .|||.|..|    | || |||
KQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIK

SSNVVIKGDFE---TIKICDVGVS
..|. .  .     ..|| | |.|
PQNIFLTKNNNDYHNVKIGDFGIS
Kinase PBK.AA TKL-Unique 34-246 27 8.9e-21 70.12 In-house 1-233 (290) Show / Hide 
Range on Protein: 34-246
Range on HMM: 1-233/290
Sequence Identity: 27% (66 aa)

FMQKLGFGTGVNVYLMKRSPRGLSH--SPWAVKKINPICNDHYRSVYQKRLMDEAKILKSLH-HPNIVGYRAFTE---ANDGSLCLAMEYGGEKSLNDLI
|  |.| |. ..||  |       .  .| |.|...|  .|   .. |. . .| ...| || ||||| | ...       . .|. |||  . ||.|..
FWNKIGEGGYGQVYKGK-------WRGYPVAIKQFHP-NEDSSNEMMQE-FENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVL

E-----ERYKASQDPFPAAIILKVALNMARGLKYLHQEKK-LLHGDIKSSNVVIKGDF----ETIKICDVGVSLPLDEN--MTVTDP----EACYIGTEP
          ..  ... . ..| |. .|.|. ||| ...  .|.|.||||. .  .       |||||.| |  .. .  ||.. .    ..  .|.  
HQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFR

WKPKEAVEEN-GVITDKADIFAFGLTLWEMMTLSI------P
| . |  . |   .. |.|...||  |||. |  |      |
WMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP
Kinase PBK.AA Ciliate-E2 78-242 21 1.4e-19 63.89 In-house 77-291 (365) Show / Hide 
Range on Protein: 78-242
Range on HMM: 77-291/365
Sequence Identity: 21% (49 aa)

YQKRLMDEAKILKSLHHPNIV-GYRAFTEANDGSLCLAMEYGGEKSLNDLIEERYKASQDPFP------AAIILKVALNMAR---------------GLK
| |..  | .||..| ||||.  | .| | .| .. | |||   ..| |.|....| ..  ..         |...    ..               .|.
Y-KKI-NEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALE

YLHQEKKLLHGDIKSSNVVIKGDFETIKICDVGVSLPLDEN----------MTVTDPE-------------------ACYIGTEPWKPKEAVEENGV---
|||.... .| ||| .|...      |||.| | |  .|..             ..                       ..|| . .. | ..  .    
YLHSKNNIIHRDIKPENILF------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ

-----ITDKADIFAFGLTLWEMMT
      . |.||...| .| ||..
QKQKGYDYKCDIWSLGVILYEMLF
Kinase PBK.AA MLK 85-242 27 3e-15 46.64 In-house 51-221 (280) Show / Hide 
Range on Protein: 85-242
Range on HMM: 51-221/280
Sequence Identity: 27% (50 aa)

EAKILKSLHHPNIVGYRAFTEANDGSLCLAMEYGGEKSLNDLIEERYKASQDPFPAAIILKVALNMARGLKYLHQEK--KLLHGDIKSSNVVIKGDFE--
||.... |.||||.  |.    .|  ||| |||    |||  .  .        |  ..   |   |||..|||.|    ..| |.||||. |.   .  
EARLFWMLKHPNIIALRGVC-LEDPHLCLVMEYCRGGSLNRVCAGK------RIPPHVLVNWAVQIARGMNYLHNEAPVPIIHRDLKSSNILILEKICLC

----------------------TIKICDVGVSLPLDENMTVTDPEACYIGTEPWKPKEAVEENGVITDKADIFAFGLTLWEMMT
                      . || | |.       .. |       ||  | . |.. | ..     |.  .|  |||..|
MDEEMFQYAYCLKCGHHDMCNKQLKITDFGLA----REWHKTT-RMSAAGTYAWMAPEVIKE-STWSKGSDVWSYGVLLWELLT
Kinase PBK.AA TK 81-243 13 1.9e-14 44.08 In-house 87-390 (486) Show / Hide 
Range on Protein: 81-243
Range on HMM: 87-390/486
Sequence Identity: 13% (42 aa)

RLMDEAKILKS--LHHPNIVGYRA-FTEAND----------GSLCLAMEY--GGE--KSLNDLIEERYKASQD---------------------------
... |.|....  .||||||   .  |.             . ... |||  .|   .|| |   .. .  |.                           
EEAEEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITY

--------------------------------------------PFPAAIILKVALNMARGLKYLHQEK-----KLLHGDIKSSNVVIKGDFE-------
                                            ... .  |  ..  |.|. |||. .     .. |.|.   |. .  .         
SHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDG

---TIKICDVG----------VSLPLDENMTVTDPEACYIGTEP----------------------WKPKEAVEE--------NGVITDKADIFAFGLTL
   ..||.| |            .. |.. ......    .                         | . |....        .|. | | |...|| ..
CGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPM-WPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLM

WEMMTL
||..|.
WEIFTY
Kinase PBK.AA TyrKc 34-318 22 2.1e-13 -5.9 SMART 3-280 (280) Show / Hide 
Range on Protein: 34-318
Range on HMM: 3-280/280
Sequence Identity: 22% (73 aa)

FMQKLGFGT--GVNVYLMKRSPRGLSHSPWAVKKINPICNDHYRSVYQKRLMDEAKILKSL--HHPNIVGYRAFTEAN------DGSLCLAMEYGGEKSL
. .||| |    |    .|         . |||.... .        .. .|.||.|...|  ||||||   .           .. |.. |||    .|
LGKKLGEGAFGEVYKGTWK--------IQVAVKMLKEDA--------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDL

NDLIEERYKASQDPFPAAIILKVALNMARGLKYLHQEKKLLHGDIKSSNVVIKGDFETIKICDVGVSLPLDEN-MTVTDPEACYIGT-----EP------
.| . .. .     .. .  |. ..  |.|  |||.  .. | |.   |. .. .. |.||.| | |  ...  ..    .  |. .     .       
KDYLRKHRPK----LCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQG--ESKDYYRKKEHKGGKTMLPIR

WKPKEAVEENGVITDKADIFAFGLTLWEMMTL-SIPHIN-----LSNDDDDEDKTFDESDFDDEAYYAALGTRPPINME--------ELDESYQKVIELF
| . |.    |. | | |...|| ..||..|.   |. .     .||              ..   |   | |.|.  .          || || ...  
WMAPECI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSN--------------QEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQ-

SVCTNEDPKDRPSAAHIVEAL
  | .|||.|||. . |.| .
--CWHEDPEDRPTFSEIHECF
Kinase PBK.AA Pkinase_Tyr 62-186 27 1.8e-09 32.66 Pfam 32-154 (270) Show / Hide 
Range on Protein: 62-186
Range on HMM: 32-154/270
Sequence Identity: 27% (35 aa)

AVKKINPICNDH-YRSVYQKRLMDEAKILKSL-HHPNIVGYRAFTEANDGS--LCLAMEYGGEKSLNDLIEERYKASQDPFPAAIILKVALNMARGLKYL
|||.... . ..     ... .| ||||.|.| |||||| . .     ...  ... |||    .| |   ..   ...|..   .|. ..  |.|. ||
AVKMLKEGAMHEQN---CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHR-EDKQPLTMKDLLQMCWQIAKGMEYL

HQEKKLLHGDIKSSNVVIKGDFETIKICD
. .|.. | |.   |. .. .. ..||||
E-SKNCIHRDLAARNCLVTENN-VVKICD
Kinase PBK.AA LRRK 85-190 27 4e-08 24.82 In-house 107-225 (351) Show / Hide 
Range on Protein: 85-190
Range on HMM: 107-225/351
Sequence Identity: 27% (34 aa)

EAKILKSLHHPNIVGYRAFTEANDGSLCLAMEYGGEKSLNDLIEERYKASQ----DPFPAAIILKVALNMARGLKYLHQEK-KLLHGDIKSSNVVIKGD-
|. |. .|.|||||    |.      ||..|||    .|....... . ..      ..  ..||.||. |.|..|||  . ...| | || |. ...  
EVWIMSHLNHPNIVSLKGFCIHP---LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSP

----------FETIKICDVGVS
          . ..||.| | |
QNHSPNYPNAHVCAKIADFGIS
Kinase PBK.AA LRRK 276-320 32 1.8e-07 22.45 In-house 305-351 (351) Show / Hide 
Range on Protein: 276-320
Range on HMM: 305-351/351
Sequence Identity: 32% (16 aa)

GTRPPINME-ELDE----SYQKVIELFSVCTNEDPKDRPSAAHIVEALET
| ||.|. . .. .    .||. |..   | ..|||.||..  ||. |..
GLRPTIPQHYCPPCQPWHMYQDLIQH---CWQHDPKKRPHFSQIVKRLSQ
Kinase PBK.AA TK 300-318 42 3.1e-05 12.65 In-house 468-486 (486) Show / Hide 
Range on Protein: 300-318
Range on HMM: 468-486/486
Sequence Identity: 42% (8 aa)

CTNEDPKDRPSAAHIVEAL
| ..||.|||. . ..|.|
CWHYDPEDRPTFSQLHEQL
Kinase PBK.AA LRRK 225-246 43 4.7e-05 13.81 In-house 260-282 (351) Show / Hide 
Range on Protein: 225-246
Range on HMM: 260-282/351
Sequence Identity: 43% (10 aa)

TDKADIFAFGLTLWEMMTLS-IP
|.|.|...||. ||| .|.. .|
TEKVDCYSFGMILWELLTRQHHP
Kinase PBK.AA Pkinase_Tyr 221-254 33 0.000429 14.49 Pfam 188-223 (270) Show / Hide 
Range on Protein: 221-254
Range on HMM: 188-223/270
Sequence Identity: 33% (12 aa)

NGVITDKADIFAFGLTLWEMMTLS-IP-HINLSNDD
.|. | | |. .|| ..||..|.  .|   ..|| .
YGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEE
Kinase PBK.AA MLK 300-318 52 0.000532 9.92 In-house 273-291 (291) Show / Hide 
Range on Protein: 300-318
Range on HMM: 273-291/291
Sequence Identity: 52% (10 aa)

CTNEDPKDRPSAAHIVEAL
| |.||..||| ..||. |
CWNQDPHKRPSFRQIVQHL
Kinase PBK.AA TKL-Unique 264-318 26 0.004292 6.97 In-house 235-290 (290) Show / Hide 
Range on Protein: 264-318
Range on HMM: 235-290/290
Sequence Identity: 26% (16 aa)

SDFDDEAYYAALGT-----RPPINMEELDESYQKVIELFSVCTNEDPKDRPSAAHIVEAL
...|.|...... .     |||| . .. ..|.. |.    | . || .|||   |.. |
QGMDQEQWCEMVHYMEENYRPPIPN-HCPKEYRDLIQQ---CWHHDPSQRPSFDEIIHRL
Kinase PBK.AA MLK 300-318 42 0.008025 4.9 In-house 262-280 (280) Show / Hide 
Range on Protein: 300-318
Range on HMM: 262-280/280
Sequence Identity: 42% (8 aa)

CTNEDPKDRPSAAHIVEAL
| | ||  ||. ..|.. |
CWNQDPHKRPKFSEILQQL
Kinase PBK.AA Pkinase_Tyr 302-318 47 0.020244 8.82 Pfam 254-270 (270) Show / Hide 
Range on Protein: 302-318
Range on HMM: 254-270/270
Sequence Identity: 47% (8 aa)

NEDPKDRPSAAHIVEAL
..||.|||. . |.| |
HYDPEDRPTFSEIHEQL