Gene SGK3 (Human)

SGK3

Species: Human
Alias: DKFZp781N0293, SGKL, SGK3, SGK2, CISK
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 8q12-q13.1,

Classification

Group: AGC
Family: SGK

Sequence

Name Sequence Type Origin Length Description Download
SGK3.NA RNA Sugen Kinome 4155 None Fasta, JSON
SGK3.AA Protein Sugen Kinome 496 None Fasta, JSON
SGK3.kin_dom Protein Kinase Domain Sugen Kinome 258 None Fasta, JSON

Protein domain

Protein domains of SGK3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PX SGK3.AA PX 11-120 30 8.3e-28 97.88 Pfam 1-120 (120) Show / Hide 
Range on Protein: 11-120
Range on HMM: 1-120/120
Sequence Identity: 30% (37 aa)

ESCPSVSIPSSDEH---REKKKRFTVYKVLVSVG---RSEWFVFRRYAEFDKLYNTLKKQFPAMAL-KIPAKRIFGD--NFDPDFIKQRRAGLNEFIQNL
..  .|..  .  |    .|.....||.. .. .   ..||.|.||| .| .|.  ||..||.. . ..|.|..||   |||..||..||..|....|..
DHFLQVHVVDPETHKHYGDKMHYYYVYEIHMNTNPFQKKEWHVWRRYSDFHWLHKQLKRHFPMCIIPPLPPKHWFGRYNNFDEEFIEKRRQMLEQYLQRV

VRYPELYN-HPDVRAFLQMD
.. ||| |  .... ||. |
CQHPELCNHCEVFHDFLHPD
PX SGK3.AA PX 13-120 25 8.3e-22 79.69 SMART 1-142 (142) Show / Hide 
Range on Protein: 13-120
Range on HMM: 1-142/142
Sequence Identity: 25% (36 aa)

CPSVSIPSSDEH------REKKKRFTVYKVLVSVG--RSEWFVFRRYAEFDKLYNTLKKQFP-----AMALKIPAKRIFGD-----------------NF
..   |  ....       ..| ...||.. .. .  ...| |.||| .| .|.. ||..||      .  ..|.| .|.                  ||
DHIFIITVVEFFTHGKHYHDGKHYYYVYEIHTKTNNHVKMWTVYRRYSDFHWLHHQLKRHFPQEKRMCIIPPLPPKHWFVRYRYWMEHMSMMWWYSFNNF

DPDFIKQRRAGLNEFIQNLVRYPELYNH----PDVRAFLQMD
|.||| .|| ||....| |.. ||. ||    ..|. |.. .
DEDFIEKRRRGLERYLQRLCHHPEWINHYMVCEVVYEFFESS
Kinase SGK3.AA SGK 162-419 65 1.1e-224 701.55 In-house 1-283 (283) Show / Hide 
Range on Protein: 162-419
Range on HMM: 1-283/283
Sequence Identity: 65% (184 aa)

FDFLKVIGKGSFGKVLLAKRKLD------------------GKFYAVKVLQKKIVL-------NRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKL
|||||||||||||||...|.| |                  .||||.|||||. ..       ..||||||||||||.|||.||||.|.|||.|||..||
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQ
|||.|.|||||.|.|||||..|||.|||||||||..||.||||..|.||||||||||||. ||..|||||||||||. .|||.|||||||||||||.|||
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

PYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGAKEDFLEIQNHPFF
|.|.||||||||.|||||.|||||||.|....|||||...|| ..|..| .||.....||.||...|||.|.||.||.|||||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase SGK3.AA AGC 162-419 36 1.1e-186 487.95 In-house 1-395 (395) Show / Hide 
Range on Protein: 162-419
Range on HMM: 1-395/395
Sequence Identity: 36% (147 aa)

FDFLKVIGKGSFGKVLLAKRK------LDGKFYAVKVLQK--KIVLNRK-EQKHIMAE------------RNVLLKNVK---------HPFLVG-LHYSF
|.||||||||||||| |...|        ||.||.|||.|  |||...| ...|.|.|            ||.| |  .         |||.|  |||||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTTEK--LYFVLD----FVN-----GG-ELFFHLQ---RERSFPEHRARFYAAE-------IASALGYLHS-IKIVYRD-LKPENILLDSVGHVVLTDFG
|. ..  ||||..    .||     || |||.|||   .|..|.| ||||||||       |..|| ||||  .|..|| |||||||||. ||. |||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LCKEGIAIS--------------------------------------------------DTTTTFCG--TPEYLAPEVIRKQPYDNTVDWWC--LGAVLY
|||||.                                                     |.|.||||  ||||.|||..    |. ..|||.  ||...|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMLYGLPPFYCR----------DVAEMYDNIL------HKPLSLR----------PGVSLTAWSILEELLEKDRQNRLGAKED------FLEIQNHPFF
|||.|.||||            . .||...|.      .... .           . .|  |..... ||.||. .|||....      . ||.|||.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase SGK3.AA Akt 162-419 53 6.7e-161 518.13 In-house 1-264 (264) Show / Hide 
Range on Protein: 162-419
Range on HMM: 1-264/264
Sequence Identity: 53% (142 aa)

FDFLKVIGKGSFGKVLLAKRKLDGKFY-AVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPE
||||||.||||||||.|.| | ..|.| | |||.|.  ..... .|...|||. |....|||.|.||||||| .|||||.|..||||||.||||.| |.|
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNI-LQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSE

HRARFYAAEIASALGYLHSIKIVYRD-LKPENILLDSVGHVVLTDFGLCKEG-IAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWC-LGAVLYEMLYG
 |||||.||| .|...|||  |.||| |||||||.|. ||. |||||||||. |   |.|.||||||||||||.. .. .. .||||  ||.|.|||..|
DRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCG

LPPFYCRDVAEMYDNILHKPLSLR--PGVSLTAWSILEELLEKDRQNRLG-AKEDFLEIQNHPFF
.|||| .|. .|...|. .|.     . .|  . .... ||.||. .||| ...|  ||..||.|
RPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase SGK3.AA PKC 162-419 47 1.6e-126 412.2 In-house 1-262 (262) Show / Hide 
Range on Protein: 162-419
Range on HMM: 1-262/262
Sequence Identity: 47% (124 aa)

FDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEH
|.||||.||||||||.||.||   ..||.||| | ...        |.|. ||    |||||..|| .||| ..|.||. .|||| | || |. | |.| 
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

RARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPF
.||||||||..|| .||.  |.||||| .|.|||. ||. ..|||.|||..   |||.||||||.|.|||... |.|   |||| .|  .|||. | .||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

YCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGAKED----FLEIQNHPFF
   |  |. ..|.|.  .     |  | ||.. ...|. ..|||....    . .|. ||||
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase SGK3.AA AktR 162-419 44 8.8e-125 420.85 In-house 1-268 (268) Show / Hide 
Range on Protein: 162-419
Range on HMM: 1-268/268
Sequence Identity: 44% (118 aa)

FDFLKVIGKGSFGKVLLAKRK-LDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPE
|...|..||| |||| |...|  ..|.|| |.. ||   .|. ..|.  |||.. . ..|||.| |||.||| |||.|..... |||||.||.... | |
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

HRARFYAAEIASALGYLHSI-KIVYRDLKPENILLDSVGHVVLTDFGLCK-EGIA-ISDTTTTFCGTPEYLAPEVIRK-QPYDNTVDWWCLGAVLYEMLY
 .||||.|.|  || |||.  .|.||||||||||||. ||| .||||| | ...   ......|||||||.|||.|.| .... .||||..|...|||..
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GLPPFYCRDVAEMYDNILHKP-LSLRPG--VSLTAWSILE-ELLEKDRQNRLG-AKEDFLEIQNHPFF
|.||||  .  .|...|. |. ..  .   .| .. ....  || |. ..||| ..... || .||.|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase SGK3.AA RSK 165-419 43 6.2e-118 398.1 In-house 1-278 (278) Show / Hide 
Range on Protein: 165-419
Range on HMM: 1-278/278
Sequence Identity: 43% (120 aa)

LKVIGKGSFGKVLLAKRK---LDGKFYAVKVLQK-KIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERS---
||| |.|..||| | ...     |. ||.|||.| ||| . | ..| |.|||.|.   .|||.| |||.||| .||| ......||||| |||.|..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDS---VGHVVLTDFGLCKEGIAI-SDTTTTFCGTPEYLAPEVIR---KQP-YDNTVDWWCLGA
| |..|.||.|||..|. .||. .|..|||||||||.|.    ||..|||||.||.. .  .  | |||.| ||.|||...   .|  .|  .||| ||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

VLYEMLYGLPPFYC---RDVAEMYDNILHKP--LSLR--PGVSLTAWSILEELLEKDRQNRLGA-KEDFLEIQNHPFF
..|||| | |||.     . .|  ..|...   |..   . .| .| ...  .|..| ..|||. ..|  ||..||.|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase SGK3.AA PKA 162-419 41 2e-110 373.14 In-house 1-263 (263) Show / Hide 
Range on Protein: 162-419
Range on HMM: 1-263/263
Sequence Identity: 41% (111 aa)

FDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVG-LHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPE
|......|.||||.| |.. | .|..|| |.| |  .  .| . |.. |.|. |.|.||||.|  . ..||.  .||.|...|.|||.| .|.....|..
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNI-LQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSN

HRARFYAA-EIASALGYLHSIKIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQ-PYDNTVDWWCLGAVLYEMLYGL
  |.|||| .| .|| ||||  |.||||||||||.|. ||. .||||  |.   . | | | ||||||||||.|    ..   ||||.|| . |||| | 
PHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKK---VDDRTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGY

PPFYCR--DVAEMYDNILHKPLSLRPGVSLTA---WSILEELLEKDRQNRLGAKE-DFLEIQNHPFF
||||    |....|. |.   .   . ..  |    . .. ||..|.  |.| .. .   | ||..|
PPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase SGK3.AA p70 162-419 42 3.3e-109 369.11 In-house 1-299 (299) Show / Hide 
Range on Protein: 162-419
Range on HMM: 1-299/299
Sequence Identity: 42% (128 aa)

FDFLKVIGKGSFGKVLLAKRKL---DGKFYAVKVLQK-KIVLNRKEQKHIM-------------------------AERNVLLKNVKHPFLVGLHYSFQT
|  |||.||| .|||.. .       || || |||.| ||| | |   |                           ||||. |  |||||.. |||.|||
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNI-LEEVKHPFICDLHYAFQT

TEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDT----------TTTFC
 .||| .|..  ||||| || |.  ..|  |.||..||  ||..||.  |.||||||||..|.. ||||||||||||| |  .            | |||
NGKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFC

GTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKP--LSLRPGVSLTAWSILEELLEKDRQNRLG-AKEDFLEIQNHPFF
||.|| |||....  ..  |||| ||. .| || | |||     ..  | ||     |.| |  .  .  ..  || .. . |.|   ||  .|| ||||
GTIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF
Kinase SGK3.AA S_TKc 162-419 37 8.49999999999e-108 365.34 SMART 1-231 (231) Show / Hide 
Range on Protein: 162-419
Range on HMM: 1-231/231
Sequence Identity: 37% (101 aa)

FDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNG--GELFFHLQRERS--
...|..||||.|||| ... | .|. .|.|..           .||. |...| |  .||..| |...||. ..||.|.....|  |.|| .... ..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----FPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDN-TVDWWCLGAVLY
    ||| .||||...|..|| |.|| .|..|||||||||||.  |. ..||||...        |||||||.|.||||.   .|.   .||| .| .||
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

EMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGAKEDFL---EIQNHPFF
|||.| |||.  ....|...|.          |  |..... .|.|| ..|..| | .    .| .||.|
EMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase SGK3.AA Eta 162-419 47 1.6e-105 356.89 In-house 1-261 (261) Show / Hide 
Range on Protein: 162-419
Range on HMM: 1-261/261
Sequence Identity: 47% (124 aa)

FDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEH
|.|.||.||||||||.||.||  .  ||.|||.| ...   .    |.|. .|    |||||  || .||| ..|.||...||||.| |..|| | | | 
FNFIKVLGKGSFGKVMLAERKGTDEVYAIKVLKKDVIIQDDDVECTMTEKRILSLARKHPFLTQLHCCFQTKDRLFFVMEYVNGGDLMFQIQRARKFDEP

RARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPF
||||||||. .|| .||   ..||||| .|||||  ||  | |||.|||||    |||||||||.|.|||... . |  .|||| .| ..|||. | |||
RARFYAAEVTCALMFLHQHGVIYRDLKLDNILLDHEGHCKLADFGMCKEGIMNGMTTTTFCGTPDYIAPEILQEMEYGPSVDWWAMGVLMYEMMCGQPPF

YCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGAKE---DFLEIQNHPFF
      .... |||        ..  | |||   . |  . |||. .   .  .|..||||
EADNEDDLFESILHDDVLYPVWLHKEAVSILKAFMTKNPHKRLGCMTAQGGEHAIRQHPFF
Kinase SGK3.AA RSK 162-419 37 1.1e-103 350.81 In-house 1-271 (271) Show / Hide 
Range on Protein: 162-419
Range on HMM: 1-271/271
Sequence Identity: 37% (102 aa)

FDFLKVIGKGSFGKVLLAKRK---LDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSF
......||.|||.|| . |..     .. ||.|...|. . ..       .||. .| .. ||| | |||.||. .|.| ..||  ||.|| .|.....|
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERI-ILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMF

PEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSV----GHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEM
.|  ..||.||||.|. |||| .||.|||||||||.|.     ||. ..|||. |. ..    . |||.| .|.||||...| .|  .||| .|...|||
SEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEM

LYGLPPFYCRDVAEMYDNILHKPLSL-------RPGVSLTAWSILEELLEKDRQNRLGA-KEDFLEIQNHPFF
| | .||. ..  .. ..|.  .| .          .| .| . |  .|. | .|||||  ..  .| .||.|
LTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase SGK3.AA Pkinase 162-419 33 4e-88 303.86 Pfam 1-293 (293) Show / Hide 
Range on Protein: 162-419
Range on HMM: 1-293/293
Sequence Identity: 33% (99 aa)

FDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIM-AERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGG----ELFFHLQ--R
. ....||.||||.| ....| .|| .|||.. |.     |.| |.  .|  ....  .||. | |...|..  ..|.|.....||    .|| ...  |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

ERSF--PEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHV----VLTDFGLCKEG-IAISDTTTTFCGTPEYLAPEVIR-KQPYDNTVDWWC
...|  .|. ..||. .|...| |.|| .|..|||||||||.|. ||.     ..||||.|   .  .  .|||||||.|.||||||  |.|.  ||.| 
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGAVLYEMLYGLPPFYCR------DVAEMYDNILHKPLSLRPGVS---------------------LTAWSILEELLEKDRQNRLGAKEDFLEIQNHPFF
.| .||||| | |||. .      |  .|...|...||.     .                      .. .... .|.|| . |..    . .| .||.|
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT----AEQILQHPWF
Kinase SGK3.AA S_TK_X 420-489 26 4.5e-15 57.32 SMART 1-79 (79) Show / Hide 
Range on Protein: 420-489
Range on HMM: 1-79/79
Sequence Identity: 26% (23 aa)

ESLSWADLVQ--KKIPPPFNPNVA----GPDDIRNFDTAFTEETVPYSVCVSSDYSIVNASVLEA-----------DDAFVGFSYAP
 .. | .| .  |.|.||| |..     .| |..|||. |||||.         .. ..  ....           .| | ||.|  
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM--------LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase SGK3.AA TyrKc 162-419 21 1.8e-13 -4.8 SMART 1-280 (280) Show / Hide 
Range on Protein: 162-419
Range on HMM: 1-280/280
Sequence Identity: 21% (63 aa)

FDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKN-VKHPFLVGLHYSFQTT-------EKLYFVLDFVNGGELFFHLQ
  ..|..| | ||.| ... |      |||.|..        .. .| | ... |   .|| .| |.    .        | |. |. .. .| |  .|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RERS-FPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAI-------SDTTTTF--CGTP----EYLAPEVIRKQPYD
. |  ..      ..  ||.   |||| ... |||   |.|... ..|  .||||....          .  ...   .|        .|||.|..  . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

NTVDWWCLGAVLYEML-YGLPPFYC-----RDVAEMYDNILHKPLSLRPGV---------SLTAWSILEELLEKDRQNRLGAKEDFLEIQNHPFF
   | |  | ...|.. || .| .       . .|.. .. .     .|           .    .| ..  . |  .|      | ||  | .|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRP----TFSEI--HECF
Kinase SGK3.AA Pkinase_C 439-491 26 2.5e-12 46.62 Pfam 1-46 (46) Show / Hide 
Range on Protein: 439-491
Range on HMM: 1-46/46
Sequence Identity: 26% (14 aa)

NVAGPDDIRNFDTAFTEETVPYSVCVSSDYSIVNASVLEADDAFVGFSYAPPS
.| .|.|..|||. ||.|......      .  . .  .....|.||.| .|.
QVKSPTDTSNFDPEFTDEPPMDTP------PDWR-MSSGDQEPFRGFTYVNPD
Kinase SGK3.AA Pkinase_Tyr 162-309 24 8.4e-08 27.04 Pfam 1-159 (270) Show / Hide 
Range on Protein: 162-309
Range on HMM: 1-159/270
Sequence Identity: 24% (39 aa)

FDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKI--VLNRKE--QKHIMAERNVLLKNV-KHPFLVGLHYSFQ-TTEK--LYFVLDFVNGGELFFHLQ
  |.|..|.|.||.| ... | |..   ..|  |..      ..  ..  |.| .. .|.  .|| .| |.       |   .| |. .. .| |  .|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKI-MKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

R----ERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHVVLTDFGLCK
.    ..... ..   ....||... ||.|.... |||   |.|... ..|  .||||..
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR