Gene Trio (Human)
Trio
Sequence
Protein domains of Trio.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| SEC14 | Trio.AA | SEC14 | 68-207 | 22 | 9.4e-29 | 102.76 | SMART | 1-184 (184) | Show / Hide |
Range on Protein: 68-207 Range on HMM: 1-184/184 Sequence Identity: 22% (41 aa) ILKEKVAYLSGGR-------DKRGGPILTFPARS------NHDRIRQEDLRRLISYLACIPSE--------EVCKRGFTVIVDMRGSK--------WDSI ... .|..||| ||.| |.. |.|. .|. ...| || ..... .. .. . .. ||..|.||.|.. |. . EHECGKHYMPGGRHGTRQGYDKDGRPVYYFRAGRHDPKGMMHSCTMHEFLRYHVYVMEKMCQHCPMCMEKMPGGQCGFHWIFDMKGWSMSHFWSPDWGWY KPLLKILQESFPCCIHVALIIKPDN------FWQKQRTNFGSSKFEFETNMVS---------LEGLTKVVDPSQLTPEFDGCLE . ...|.|...| ..| ..||.| .| |. | ..|. . .|. | |.| .||..|. |. | .. RKMWQIFQDHYPERLHKVYIINPPWWMFFFWVWWKMIKPFLDEKTREKIHFVGPNKVDDNDWKEELHKYIDPECLPEEWGGTCD |
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| SPEC | Trio.AA | SPEC | 221-337 | 16 | 2e-11 | 45.2 | SMART | 1-104 (104) | Show / Hide |
Range on Protein: 221-337 Range on HMM: 1-104/104 Sequence Identity: 16% (20 aa) EDYISNATHMLSRLEELQDILAKKELP--QDLEGARNMIEEHSQLKK--KVIKAPIEDLDLEGQKLLQRIQSSESFPKKNSGSGNADLQNLLPKVSTMLD . . ... ... ..| . .|. .... .|||........| ...| . .. ...|. .||.|.|. .|..| ... .. | QQFHRDCDELEQWMDEKEQLLSSDDYGDSKDLESVQALQKKHQAFEKEMEAHQPRVDQLNQQGQQLIQE-------------YGHYDADEIQERL----D RLHSTRQHLHQMWHVRKLKLD .|.. ...|...| |. .|. ELNQRWEELCELWEERRQRLE |
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| Spectrin | Trio.AA | Spectrin | 218-338 | 13 | 0.097741 | 9.59 | Pfam | 1-109 (109) | Show / Hide |
Range on Protein: 218-338 Range on HMM: 1-109/109 Sequence Identity: 13% (17 aa) VAFEDYISNATHMLSRLEELQDILAKKEL-PQDLEGARNMIE--EHSQLKK--KVIKAPIEDLDLEGQKL-LQRIQSSESFPKKNSGSGNADLQNLLPKV .. . ... .... ..| .|. .. ..|||..... . | .... . . ...|. ..||| ... ... . . HHLQQFQRDCDDLEQWIQEKEQWLSSEDYWGKDLEEVQALQKQWKHQAFEAEIAAHQDRVQQLNEQAQKLIIDEGHHDS------------------EEI STMLDRLHSTRQHLHQMWHVRKLKLDQ ..... |.. ...|...| || || . QERMEELNQRWEQLCELWEERKQKLEE |
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| SPEC | Trio.AA | SPEC | 343-445 | 19 | 1.4e-17 | 65.64 | SMART | 1-104 (104) | Show / Hide |
Range on Protein: 343-445 Range on HMM: 1-104/104 Sequence Identity: 19% (21 aa) RLFEQDAEKMFDWITHNKGLFLNSYTEIG--TSHPHAMELQTQHNHFAMNCMNVYVNINRIMSVANRLVES-GHYASQQIRQIASQLEQEWKAFAAALDE . | .|.. . .|.. . | | ...| . .....|| .| | . .. . ...|... |||....|.. .|.|.|.. ....| QQFHRDCDELEQWMDEKE--QLLSSDDYGDSKDLESVQALQKKHQAFEKEMEAHQPRVDQLNQQGQQLIQEYGHYDADEIQERLDELNQRWEELCELWEE RSTLLD | |. RRQRLE |
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| Spectrin | Trio.AA | Spectrin | 340-446 | 21 | 2.7e-07 | 30.28 | Pfam | 1-109 (109) | Show / Hide |
Range on Protein: 340-446 Range on HMM: 1-109/109 Sequence Identity: 21% (24 aa) FQLRLFEQDAEKMFDWITHNKGLFLNSYTEI-GTSHPHAMELQT--QHNHFAMNCMNVYVNINRIMSVANRL-VESGHYASQQIRQIASQLEQEWKAFAA .|. | .|.. . ||. .| | .. | . ....|| .| | . . ... . .|..| ...||..|..|.. ..|.| |.. . HHLQQFQRDCDDLEQWIQEK-EQWL-SSEDYWGKDLEEVQALQKQWKHQAFEAEIAAHQDRVQQLNEQAQKLIIDEGHHDSEEIQERMEELNQRWEQLCE ALDERSTLLDM ...|| | LWEERKQKLEE |
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| SPEC | Trio.AA | SPEC | 569-671 | 26 | 2.1e-16 | 61.72 | SMART | 1-104 (104) | Show / Hide |
Range on Protein: 569-671 Range on HMM: 1-104/104 Sequence Identity: 26% (28 aa) CVFQQDVQQVLDWIENHGEAFLSKHTGVG--KSLHRARALQKRHEDFEEVAQNTYTNADKLLEAAEQLAQT-GECDPEEIYQAAHQLEDRIQDFVRRVEQ |..|......|... | ... .| |.| ..||||.|..||. .. |.| ....|| | |. | .|| . ..|..| .. ...|. QQFHRDCDELEQWMDEKE--QLLSSDDYGDSKDLESVQALQKKHQAFEKEMEAHQPRVDQLNQQGQQLIQEYGHYDADEIQERLDELNQRWEELCELWEE RKILLD |. |. RRQRLE |
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| Spectrin | Trio.AA | Spectrin | 566-672 | 29 | 7.5e-05 | 21.2 | Pfam | 1-109 (109) | Show / Hide |
Range on Protein: 566-672 Range on HMM: 1-109/109 Sequence Identity: 29% (33 aa) LQLCVFQQDVQQVLDWIENHGEAFLSKHTGV-GKSLHRARALQK--RHEDFEEVAQNTYTNADKLLEAAEQL-AQTGECDPEEIYQAAHQLEDRIQDFVR ..| ||.|..... ||. |..| . ||.| ..|||| .|..||. .. .. ..| | |..| .. | |.||| . .|..| .. . HHLQQFQRDCDDLEQWIQEK-EQWL-SSEDYWGKDLEEVQALQKQWKHQAFEAEIAAHQDRVQQLNEQAQKLIIDEGHHDSEEIQERMEELNQRWEQLCE RVEQRKILLDM ..|.|| | LWEERKQKLEE |
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| SPEC | Trio.AA | SPEC | 674-783 | 24 | 4.7e-09 | 37.31 | SMART | 1-104 (104) | Show / Hide |
Range on Protein: 674-783 Range on HMM: 1-104/104 Sequence Identity: 24% (27 aa) VSFHTHVKELWTWLEELQKELLDDVYA--ESVEAVQDLIKRFGQQQQTTLQVTVNVIKEGEDLIQQLRDSAISSNKTPHNSSINHIETVLQQLDEAQSQM || ..|| |..| .. | .| |. ..|.||.|.| |. .. .. . ... ... ||| .. .. .|. |..|... . QQFHRDCDELEQWMDEKEQLLSSDDYGDSKDLESVQALQK-KHQAFEKEMEAHQPRVDQLNQQGQQLIQE-------YGHYDADEIQERLDELNQRWEEL EELFQERKIKLE .|| .||. .|| CELWEERRQRLE |
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| Spectrin | Trio.AA | Spectrin | 676-718 | 27 | 0.208992 | 8.36 | Pfam | 6-48 (109) | Show / Hide |
Range on Protein: 676-718 Range on HMM: 6-48/109 Sequence Identity: 27% (12 aa) FHTHVKELWTWLEELQKELLDDVY-AESVEAVQDLIKRFGQQQQ |. ....| |..| . | .. | ....|.|| | | . ..|. FQRDCDDLEQWIQEKEQWLSSEDYWGKDLEEVQALQKQW-KHQA |
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| SPEC | Trio.AA | SPEC | 910-1011 | 20 | 1e-14 | 56.12 | SMART | 1-104 (104) | Show / Hide |
Range on Protein: 910-1011 Range on HMM: 1-104/104 Sequence Identity: 20% (21 aa) RHLQAEVKQVLGWIRNGESMLNAGLIT-ASSLQEAEQLQREHEQFQHAIEKTHQSALQVQQKAEAMLQA-NHYDMDMIRDCAEKVASHWQQLMLKMEDRL ........... |... | .|. . . .|.....||..|..|.. .| ... |..| .....|. .||| | |.. ... ..|..| ..|.| QQFHRDCDELEQWMDEKEQLLSSDDYGDSKDLESVQALQKKHQAFEKEMEAHQPRVDQLNQQGQQLIQEYGHYDADEIQERLDELNQRWEELCELWEERR KLVN . . QRLE |
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| Spectrin | Trio.AA | Spectrin | 907-1012 | 23 | 8e-06 | 24.85 | Pfam | 1-109 (109) | Show / Hide |
Range on Protein: 907-1012 Range on HMM: 1-109/109 Sequence Identity: 23% (26 aa) VQLRHLQAEVKQVLGWIRNGESMLNAGLITASSLQEAEQLQR--EHEQFQHAIEKTHQSAL-QVQQKAEAM-LQANHYDMDMIRDCAEKVASHWQQLMLK .|. .| ...... ||. | .|.. . . .|.|...||. |..|.. |. || . |... |... ....|.|.. |.. | . ..|.|| HHLQQFQRDCDDLEQWIQEKEQWLSSEDYWGKDLEEVQALQKQWKHQAFEAEIAA-HQDRVQQLNEQAQKLIIDEGHHDSEEIQERMEELNQRWEQLCEL MEDRLKLVNA .|.| . . WEERKQKLEE |
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| SPEC | Trio.AA | SPEC | 1141-1243 | 22 | 2.8e-20 | 74.63 | SMART | 1-104 (104) | Show / Hide |
Range on Protein: 1141-1243 Range on HMM: 1-104/104 Sequence Identity: 22% (24 aa) VVFERSAKQALEWIHDNGEFYLSTHTSTG--SSIQHTQELLKEHEEFQITAKQTKERVKLLIQLADGFCEK-GHAHAAEIKKCVTAVDKRYRDFSLRMEK | | ......|. . | ... .| .... |.|.|.|..|. .. ..||. |.|... .... ||..|.||.. ......|... ..|. QQFHRDCDELEQWMDEKE--QLLSSDDYGDSKDLESVQALQKKHQAFEKEMEAHQPRVDQLNQQGQQLIQEYGHYDADEIQERLDELNQRWEELCELWEE YRTSLE | || RRQRLE |
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| Spectrin | Trio.AA | Spectrin | 1138-1244 | 22 | 6.3e-09 | 36.4 | Pfam | 1-109 (109) | Show / Hide |
Range on Protein: 1138-1244 Range on HMM: 1-109/109 Sequence Identity: 22% (25 aa) QQYVVFERSAKQALEWIHDNGEFYLSTHTSTGSSIQHTQELLK--EHEEFQITAKQTKERVKLLIQLADGF-CEKGHAHAAEIKKCVTAVDKRYRDFSLR ... | | ......|| . | .||. | .....|.|.| |..|. . ..||. | ..|. . . || . ||.. . ....|. . . HHLQQFQRDCDDLEQWIQEK-EQWLSSEDYWGKDLEEVQALQKQWKHQAFEAEIAAHQDRVQQLNEQAQKLIIDEGHHDSEEIQERMEELNQRWEQLCEL MEKYRTSLEK .| . || WEERKQKLEE |
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| RhoGEF | Trio.AA | RhoGEF | 1296-1466 | 28 | 1.1e-55 | 192.25 | SMART | 1-211 (211) | Show / Hide |
Range on Protein: 1296-1466 Range on HMM: 1-211/211 Sequence Identity: 28% (60 aa) IMAELIQTEKAYVRDLRECMDTYLWEMTSGV--EEIPPGIVNKELIIFG-NMQEIYEFHNNIFLKELEKYEQL------------------PEDVGHCFV .. ||.|||..|||||......|. .| . . ..|. .. .||| |..|||||| ..||.|||.. .. ....|.||. VIQELMQTERNYVRDLHIIVQHYMKPMQKEEKCHKLPFLSPDEVNHIFGPNIEEIYEFH-RRFLDELEERIEEWDCSMDWKSFRNFQIRDICDRIGDCFM TW---ADKFQMYVTYCKNKPDSTQLILE-----HAGSYFDEIQQRHGLAN---------SISSYLIKPVQRITKYQLLLKELLTCCE---EGKGEIKDGL | .. |.|| .||.|.|.. ... . . ......... .| .....||||.||||||.|||||.| ... . . .... | KWFHAEEMFKMYSEYCNNHPYALKHLKKWMCCKKNPRFQKFCKECESHPNCRSNSEHRLTLEDFLIKPMQRITKYPLLLKEILKHTPPDHPDYEDLQKAL EVMLSVPKRAND ..| .|... |. DCMKDVAQHCNE |
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| RhoGEF | Trio.AA | RhoGEF | 1296-1466 | 29 | 9.6e-47 | 162.29 | Pfam | 1-196 (196) | Show / Hide |
Range on Protein: 1296-1466 Range on HMM: 1-196/196 Sequence Identity: 29% (59 aa) IMAELIQTEKAYVRDLRECMDTYLWEMTS--GVEEIPPGIVNKELIIFGNMQEIYEFHNNIFLKELEK-----YE--QLPED--VGHCF--VT-WADKFQ .. |.||||..|||||. . . |. .. . . ..|. .. .||.| .||||||.. ||..||. ... .|.|| . ... |. VIQEIIQTERSYVRDLNIIIEHYMKPLRNCANPPILSPDEIH---TIFSNIEEIYEFHQR-FLEDLEERDRMECWNPPDYQCQTIGDCFMFLKHMFPFFK MYVTYCKNKPDSTQLILEHAGS--YFDEIQQRHGLANS---------ISSYLIKPVQRITKYQLLLKELLTCCEE-----GKGEIKDGLEVMLSVPKRAN ||..||.|.| . .|. .. . .|... .. . . ..|.||||||||..|.||||||| .... . ... ||.| .| ...| MYSEYCNNYPKAMKLLKKCRKKNPKFQQFLKWCEKE-NDPCCRRLDLLQSFLIKPVQRIPRYPLLLKELLKHTPPCDHPKDYEDLQKALEAMKEVASHIN D . E |
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| PH | Trio.AA | PH | 1480-1591 | 18 | 8.2e-15 | 56.06 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 1480-1591 Range on HMM: 1-92/92 Sequence Identity: 18% (21 aa) IESQGELILQESFQVWDPKTLIRKGRERHLFLFEMSLVFSKEVKDSSGRSKYLYKSKLFTSELGVTEHVEG-DPCKFALWVGRTPTSDNKIVLKASSIEN .. .|.| ... ... ..|...||. |.. |. | | .| .. |.. ||..... .|. | .. ......|.| | VIKEGWLHKKG---------KRKSWKKRWFVLFNNCLYYYKDDK-------YRPKGSIPLSDCQVTKVPDNKRPHCFQIRT-DR----RTYYFQAESEEE KQDWIKHIREVIQ ..||...|.... MNDWMQAIQSACR |
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| PH | Trio.AA | PH | 1480-1593 | 15 | 4.5e-12 | 47.36 | SMART | 1-82 (82) | Show / Hide |
Range on Protein: 1480-1593 Range on HMM: 1-82/82 Sequence Identity: 15% (18 aa) IESQGELILQESFQVWDPKTLIRKGRERHLFLFEMSLVFSKEVKDSSGRSKYLYKSKLFTSELGVTEHVEGDPCKFALWVGRTPTSDNKIVLKASSIENK .. .| | .. . ..|...||. .|.. |. .| ... |.. |.| . | .. ......| | . VIKEGWLYKKS----------K-RWKKRWFVLFNDCLYYYKDK---------KPKGSIPLSDCTVRE-P-----CFEIHH-DR-----TYYFQCESEEEM QDWIKHIREVIQER |.|...|...|.. QEWMQAIQKAIHNN |
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| SH3_1 | Trio.AA | SH3_1 | 1662-1713 | 28 | 3e-11 | 40.98 | Pfam | 1-49 (49) | Show / Hide |
Range on Protein: 1662-1713 Range on HMM: 1-49/49 Sequence Identity: 28% (15 aa) VVIHDFTACNSNELTIRRGQTVEVLERPHDKPDWCLVRTTDRSPAAEGLVPC |...|..| ...||....| ...|.|. .| .||. .| .. ||..|. VALYDYQAQQPDELSFKKGDIIHVIEKSDD-WDWWKGRCNNT--GQEGWFPS |
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| SH3 | Trio.AA | SH3 | 1659-1720 | 22 | 7.3e-11 | 43.34 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 1659-1720 Range on HMM: 1-58/58 Sequence Identity: 22% (14 aa) ELTVVIHDFTACNSNELTIRRGQTVEVLERPHDKPDWCLVRTTDRSPAAEGLVPCGSLCIAH . ....|..|.|..||....|....|||. ..|. .| . ||..|. . . . PYVRALYDYQAQNPDELSFKKGDIITVLEKD--DDGWWKGRCNR--TGQEGWFPSNYVEEID |
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| SH3_2 | Trio.AA | SH3_2 | 1660-1712 | 16 | 1.6e-05 | 22.24 | Pfam | 1-61 (68) | Show / Hide |
Range on Protein: 1660-1712 Range on HMM: 1-61/68 Sequence Identity: 16% (11 aa) LTVVIHDFTA-CNSNE-----LTIRRGQTVEVL----ERPHDKPDWCLV-RTTDRSPAAE--GLVP . .|. |... .. || |....|....|. .... .|... .|... . |..| YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWD---NWWWCWETIWG--GRRMRGWFP |
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| RhoGEF | Trio.AA | RhoGEF | 1973-2144 | 32 | 6e-67 | 229.64 | SMART | 1-211 (211) | Show / Hide |
Range on Protein: 1973-2144 Range on HMM: 1-211/211 Sequence Identity: 32% (69 aa) VLQELVETERDYVRDLGYVVEGYMALMKEDG----VPDDMKGKDKIVFG-NIHQIYDWHRDFFLGELEKCLED------------------PEKLGSLFV |.|||..|||.||||| ..|..|| |.... .|. . ...|| ||. ||. ||.|.. |||...|. ....|..|. VIQELMQTERNYVRDLHIIVQHYMKPMQKEEKCHKLPFLSPDEVNHIFGPNIEEIYEFHRRFLD-ELEERIEEWDCSMDWKSFRNFQIRDICDRIGDCFM KH---ERRLHMYIAYCQNKPKSEHIVSE-----YIDTFFEDLKQRLGH---------RLQLTDLLIKPVQRIMKYQLLLKDFLKYSKKASLDTSELERAV |. |....||..||.|.|..... .. . |.. .|.. | ||.|.|.||||.|||.||.||||. ||...... | .|..|. KWFHAEEMFKMYSEYCNNHPYALKHLKKWMCCKKNPRFQKFCKECESHPNCRSNSEHRLTLEDFLIKPMQRITKYPLLLKEILKHTPPDHPDYEDLQKAL EVMCIVPRRCND ..|. |...||. DCMKDVAQHCNE |
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| RhoGEF | Trio.AA | RhoGEF | 1973-2144 | 31 | 3.6e-55 | 191.24 | Pfam | 1-196 (196) | Show / Hide |
Range on Protein: 1973-2144 Range on HMM: 1-196/196 Sequence Identity: 31% (63 aa) VLQELVETERDYVRDLGYVVEGYM-ALMKEDGVPDDMK-GKDKIVFGNIHQIYDWHRDFFLGELEK-------CLEDPEK--LGSLF--VK-HERRLHMY |.||...|||.||||| ...|.|| |.... .|. .. .. ...|.||..||..|..| | .||. .. |... .| .| .| ... ..|| VIQEIIQTERSYVRDLNIIIEHYMKPLRNCA-NPPILSPDEIHTIFSNIEEIYEFHQRF-LEDLEERDRMECWNPPDYQCQTIGDCFMFLKHMFPFFKMY IAYCQNKPKSEHIVSEYIDT--FFEDLKQ--RL-----GHRLQ-LTDLLIKPVQRIMKYQLLLKDFLKYSKK-ASL-DTSELERAVEVMCIVPRRCND . ||.|.||.. ..... . .|... . .. .||. | ..||||||||..|.||||. ||.... . | ..|..|.|.| | ...|. SEYCNNYPKAMKLLKKCRKKNPKFQQFLKWCEKENDPCCRRLDLLQSFLIKPVQRIPRYPLLLKELLKHTPPCDHPKDYEDLQKALEAMKEVASHINE |
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| PH | Trio.AA | PH | 2158-2271 | 13 | 5e-10 | 38.82 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 2158-2271 Range on HMM: 1-92/92 Sequence Identity: 13% (16 aa) IVAQGKLLLQDTFLVTDQDAGLLPRCRERRIFLFEQIVIFSEPLDKKKGFSMPGFLFKNSIKVSCLCLEENVEN-DPCKFALTSRTGDVVETFILHSSSP .. .| |... . . ..| ..||.. ... .. . . | || .| . ... ..| .|. | ... .. .|.... .|. VIKEGWLHKKG----------KRKSWKKRWFVLFNNCLYYYKDDK---------YRPKGSIPLSDCQVTKVPDNKRPHCFQIRT-DR---RTYYFQAESE SVRQTWIHEINQILE ...|.. |.... EEMNDWMQAIQSACR |
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| PH | Trio.AA | PH | 2158-2273 | 15 | 5.6e-08 | 33.74 | SMART | 1-82 (82) | Show / Hide |
Range on Protein: 2158-2273 Range on HMM: 1-82/82 Sequence Identity: 15% (18 aa) IVAQGKLLLQDTFLVTDQDAGLLPRCRERRIFLFEQIVIFSEPLDKKKGFSMPGFLFKNSIKVSCLCLEENVENDPCKFALTSRTGDVVETFILHSSSPS .. .| |. . . | ..| .||.. ... .. | || .| . ..| . | ... .. |.... .|.. VIKEGWLYKKS-----------K-RWKKRWFVLFNDCLYYYKDK-----------KPKGSIPLSDCTVRE-P-----CFEIHH-DR----TYYFQCESEE VRQTWIHEINQILENQ .| |.. |.. ..|. EMQEWMQAIQKAIHNN |
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| SH3 | Trio.AA | SH3 | 2554-2623 | 20 | 0.001456 | 10.96 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 2554-2623 Range on HMM: 1-58/58 Sequence Identity: 20% (14 aa) STMLVTHDYTAVKEDEINVYQGEVVQILASNQQNMFLVFRAATDQCPAAEGWIPGFVLGHTSAVIVENPD .. . .||.| .||. . .|.....| . .. . . . |||.| . || | PYVRALYDYQAQNPDELSFKKGDIITVLEKDDDGWWKGRCNR----TGQEGWFP--------SNYVEEID |
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| SH3_1 | Trio.AA | SH3_1 | 2560-2582 | 26 | 0.078811 | 9.4 | Pfam | 4-26 (49) | Show / Hide |
Range on Protein: 2560-2582 Range on HMM: 4-26/49 Sequence Identity: 26% (6 aa) HDYTAVKEDEINVYQGEVVQILA .||.|. .||. .|....... YDYQAQQPDELSFKKGDIIHVIE |
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| SH3_2 | Trio.AA | SH3_2 | 2555-2581 | 18 | 0.278217 | 7.38 | Pfam | 1-33 (68) | Show / Hide |
Range on Protein: 2555-2581 Range on HMM: 1-33/68 Sequence Identity: 18% (6 aa) TMLVTHDYTA-VKEDE-----INVYQGEVVQIL . |. ||.. ...| ... |.|. .. YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVI |
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| I-set | Trio.AA | I-set | 2685-2776 | 31 | 2.5e-25 | 88.46 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 2685-2776 Range on HMM: 1-92/92 Sequence Identity: 31% (29 aa) PEFVIPLSEVTCETGETVVLRCRVCGRPKASITWKGPEHNTLNNDGHYSISYSDLGEATLKIVGVTTEDDGIYTCIAVNDMGSASSSASLRV |.|..... |.. |||. . |.| | |. ...|. . ... .....|.. |..|| | .|. .| |.|||.|.| |.|...|.| | PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV |
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| IGc2 | Trio.AA | IGc2 | 2697-2766 | 31 | 8.6e-15 | 56.39 | SMART | 1-56 (56) | Show / Hide |
Range on Protein: 2697-2766 Range on HMM: 1-56/56 Sequence Identity: 31% (22 aa) ETGETVVLRCRVCGRPKASITWKGPEHNTLNNDGHYSISYSDLGEATLKIVGVTTEDDGIYTCIAVNDMG . |..|.|.|.. |.| ..|.|. .. . .. ||.| || ||.|.|||.| | .| HEGQSVTLTCPATGNPDPNIHWYK---GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG |
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| IG | Trio.AA | IG | 2691-2777 | 26 | 3.9e-14 | 54.22 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 2691-2777 Range on HMM: 1-58/58 Sequence Identity: 26% (24 aa) LSEVTCETGETVVLRCRVCGRPKASITWKGPEHNTLNNDGHYSISYSDLGEATLKIVGVTTEDD---GIYTCIAVNDMGSASS--SASLRVL . || ||||.|.| | .|.|. | | .|. || |.|.| | |...| .. |.|. PP-VTVKEGETVTLTC-VS-----QIWWY------------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ |
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| V-set | Trio.AA | V-set | 2685-2776 | 15 | 5.2e-05 | 19.12 | Pfam | 1-128 (128) | Show / Hide |
Range on Protein: 2685-2776 Range on HMM: 1-128/128 Sequence Identity: 15% (20 aa) PEFVIP--LS----EVTCETGETVVLRCRVC-----------------GRP-----------KASITWKGPEHNTLNNDGHYSISYSDL-GEATLKIVGV ...| . . .|| ..|..| |.| . ..| . .| . . | ...| . . ..|.| . QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNL TTEDDGIYTCIAVN-DMGSASSSASLRV . .| |.|.| . | .... .. |.| QPSDSGTYYCAVWNCNEDYFGHGTRLTV |
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| Kinase | Trio.AA | Trio | 2796-3050 | 55 | 7.80000000001e-232 | 602.31 | In-house | 1-258 (258) | Show / Hide |
Range on Protein: 2796-3050 Range on HMM: 1-258/258 Sequence Identity: 55% (143 aa) YSEVAELGRGRFSVVKKCDQKGTKRAVATKFVNKKLMKRDQVTHELGILQSLQHPLLVGLLDTFETPTSYILVLEMADQGRLLDCVVRWGSLTEGKIRAH |....|.||||||||..|..|.|.|..|.||.....|...||.||...||.||||....|.||.|||..|||.||..|.|.||.|..||||..|...... YTFQEEIGRGRFSVVRRCWHKATGRTCAAKFIPYRMMDKEQVYHEYEMLQHLQHPCVCSLHDTYETPRHYILILELCDDGELLCCLMRWGSYCESEVKTY LGEVLEAVRYLHNCRIAHLDLKPENILVDESLA-KPTIKLADFGDAVQLNTT--YYIHQLLGNPEFAAPEIILGNPVSLTSDTWSVGVLTYVLLSGVSPF ....||||.|||||.|.|||.||||.......| .|.||..|||||.||... ...|...|||||.||||| |||||...|.||.||||||.|||.||| MWQMLEAVHYLHNCHILHLDIKPENMMMWHYNAGRPQIKICDFGDAQQLWPHKVEPQHHQYGNPEFMAPEIIQGNPVSYGTDIWSIGVLTYVMLSGISPF LDDSVEETCLNICRLDFSFPDDYFKGVSQKAKEFVCFLLQEDPAKRPSAALALQEQWL .|.|..|||.||||.|||||..||..|||.||.|.|..|||||.|||.|. .||..|. YDESDRETCMNICRGDFSFPECYFCHVSQNAKHFICKVLQEDPWKRPCASECLQHPWF |
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| Kinase | Trio.AA | DAPK | 2798-3050 | 38 | 1.2e-96 | 266.7 | In-house | 1-264 (264) | Show / Hide |
Range on Protein: 2798-3050 Range on HMM: 1-264/264 Sequence Identity: 38% (102 aa) EVAELGRGRFSVVKKCDQKGTKRAVATKFVNKKLMKRD-------QVTHELGILQSLQ-HPLLVGLLDTFETPTSYILVLEMADQGRLLDCVVR--WGSL |||||.|.||.|| .| | . | ||. | .... || ||. .. || ...| . .|| | ||.|| . | | | .. .| MGEELGRGQFAVVRKCRHKSTGKHYAAKFIKKRRRGQSRRGVCREEIEHEIAILEECRGHPNVINLHEVYETRTDVILILEYVSGGELFDYCCEDREECL TEGKIRAHLGEVLEAVRYLHNCRIAHLDLKPENILVDE-SLAKPTIKLADFGDAVQLNTTYYIHQLLGNPEFAAPEIILGNPVSLTSDTWSVGVLTYVLL .| .. . ..||.|.||| .|.||||||.||. .. ||. ||| . .. . | ||. ||||. | || | ||.||.||..| CEEDATRFMKQILEGVHYLHSRNICHLDLKPQNIMLTDRNIPQGDIKIIDFGLSRKICNGEEFRDIMGTPEYVAPEIVNYEPLSLATDMWSIGVITYIML SGVSPFLDDSVEETCLNICRLDFSFPDDYFKGVSQKAKEFVCFLLQEDPAKRPSAALALQEQWL || |||| | || ||| .. .|.. ||...|. || | || || ||..|. .|| |. SGISPFLGDTKQETFLNISQVNYDFSEEYFSCTSEHAKDFIRRLLVKDPEKRMTAEECLQHPWI |
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| Kinase | Trio.AA | CAMK | 2801-3050 | 21 | 2e-94 | 304.65 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 2801-3050
Range on HMM: 1-425/425
Sequence Identity: 21% (92 aa)
ELGRGRFSVVKKCDQKGTK------------RAVATKFVNKK-----------------------------LMKRDQVTHELGILQSLQ-------HPLL
.||||.|..||.| .| |. . || |...|| .|..| .|. |...|| || .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
VGLLDTFE------------TPTS--------YILVL---EMADQG----RLLDCVVR---------------WGSLTEGKIRAHLGEVLEAVRYLHNCR
. |....| | . ...|. |... | .|.| .|. .| .|| | ...||.|.|..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN
IAHLDLKPENILVDESLAKP--------------TIKLADFGDAVQLNT------------------------TYYIHQLLGNPEFAA-PEIILG-----
|.|.||||||||.|.. .||..||| | ... . . | ||..| ||...|
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN
---------NPVSLTSDTWSVGVLTYVLLSGVSPFLDD-------------SVEETCLNICRLDFSFPDDYFKGVS--------------------QKAK
... .| ||.||..|..|.| .|| .| . .|.. .|.. ...||..||...| | .|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK
EFVCFLLQEDPAKRPSAALALQEQWL
... .|| || ||.... .|. .|.
DLIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | Trio.AA | MLCK | 2796-3050 | 37 | 7.2e-91 | 239.51 | In-house | 1-257 (257) | Show / Hide |
Range on Protein: 2796-3050 Range on HMM: 1-257/257 Sequence Identity: 37% (96 aa) YSEVAELGRGRFSVVKKCDQKGTKRAVATKFVNK-KLMKRDQVTHELGILQSLQHPLLVGLLDTFETPTSYILVLEMADQGRLLDCVVRWG-SLTEGKIR |. |||||.|..| .| .| |....| ||. | ... | .| |. |.|| |. . | |||... ....| . | |.. .| . ||| .. YQIHEELGRGKFGIVHRCIEKSTGKTWAAKFIKCRKPKDKENVKNEIEIMNQLHHPNLIQCHDAFETKNEMVMIMEYISGGELFERIVDEDFHLTEREVI AHLGEVLEAVRYLHNCRIAHLDLKPENILVDESLAKPTIKLADFGDAVQLNTTYY-IHQLLGNPEFAAPEIILGNPVSLTSDTWSVGVLTYVLLSGVSPF . ..|.|...| .|.|||||||||. . .||. ||| | ... . . | |||.|||.. ||.. .| |||||..|.|||| ||| HYMRQICEGVHHMHWQNIVHLDLKPENIMCQTRTSH-QIKIIDFGLARKYDPDEKKVKVMFGTPEFVAPEVVNYDPVGFQTDMWSVGVICYMLLSGLSPF LDDSVEETCLNICRLDFSFPDDYFKGVSQKAKEFVCFLLQEDPAKRPSAALALQEQWL . |. .|| |. . | |. |...|. || |.. || .|. ||..|. .|| || MGDNDRETMNNVTSCEWDFDDECFDDISDEAKDFISRLLVKDKEKRMTAHECLQHPWL |
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| Kinase | Trio.AA | DRAK | 2798-3050 | 35 | 4.6e-79 | 245.23 | In-house | 1-259 (259) | Show / Hide |
Range on Protein: 2798-3050 Range on HMM: 1-259/259 Sequence Identity: 35% (91 aa) EVAELGRGRFSVVKKCDQKGTKRAVATKFVNKKLMKRD---QVTHELGILQ-SLQHPLLVGLLDTFETPTSYILVLEMADQGRLLD-CVV-RWGSLTEGK |.|||.| || || .| | . | ||. | . .| . || .| . . | ...| . .|| . ||||| | | . . || . ..| TAKERGRGKFAVVRKCIHKNTGQHFAAKFMKKRRRGQDCRMEILHEIAVLMLCQDCPWVINLHEVYETRSEMILVLEYAAGGEIFQYCVADKEECFCEKD IRAHLGEVLEAVRYLHNCRIAHLDLKPENILVDESLAKPTIKLADFGDAVQLNTTYYIHQLLGNPEFAAPEIILGNPVSLTSDTWSVGVLTYVLLSGVSP .. . ..||.|.|||. |.|||||| ||| ||. ||| . .. . . | |.. |||| .|... | ||.||||||.|...|| VQRCMRQILEGVHYLHQRNIVHLDLKPQNILLTSEYPEDDIKICDFGMSRYICNGEEVREIMGTPDYVAPEILNYDPITMATDMWSIGVLTYVMLTHISP FLDDSVEETCLNICRLDFSFPDDYFKGVSQKAKEFVCFLLQEDPAKRPSAALALQEQWL |. | || ||| . ..... | ..|. | |. |. .| .|..| |. || FVGDDKQETFLNISQCNLDYSEEMFSCHSPVAIDFIQSLCVIKPEDRMTAEECLDHPWL |
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| Kinase | Trio.AA | DAPK | 2796-3050 | 38 | 5.3e-77 | 221.6 | In-house | 1-264 (264) | Show / Hide |
Range on Protein: 2796-3050 Range on HMM: 1-264/264 Sequence Identity: 38% (102 aa) YSEVAELGRGRFSVVKKCDQKGTKRAVATKFVNKKLM-------KRDQVTHELGILQSLQ-HPLLVGLLDTFETPTSYILVLEMADQGRLLDCVVRWGSL | |.| | |.||||| .|.| | ||. | . .|. . | ||. .. || . | | .|. | .|.|| | | | . .| YDMGEEIGSGQFAVVKKCREKSTGKEYAAKFIKKRRYTASRRGVSREDIEREVSILREIRGHPNIITLHDVYENKTDVVLILELVSGGELFDFLCEKECL TEGKIRAHLGEVLEAVRYLHNCRIAHLDLKPENI-LVDESLAKPTIKLADFGDAVQLNTTYYIHQLLGNPEFAAPEIILGNPVSLTSDTWSVGVLTYVLL .| . . .|..|...| .|.|.||||||| | | ..| ||. ||| | . . ..| ||| ||||. | .| | ||.|| ||.|| NEEEATQFIKQILDGVHHMHSKHICHFDLKPENIMLLDRNVPNPRIKIIDFGLAHRIEPGNEFKNIFGTPEFVAPEIVNYEPLGLETDMWSIGVITYILL SGVSPFLDDSVEETCLNICRLDFSFPDDYFKGVSQKAKEFVCFLLQEDPAKRPSAALALQEQWL || |||| | .|| || . . | . ||| |. || |. || || || . .|| | SGASPFLGDTKQETLANITAVNYHFDEEYFKNTSEHAKDFIRRLLVKDPKKRMTIQECLQHPWI |
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| Kinase | Trio.AA | S_TKc | 2796-3050 | 30 | 7.9e-75 | 255.82 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 2796-3050 Range on HMM: 1-231/231 Sequence Identity: 30% (84 aa) YSEVAELGRGRFSVVKKCDQKGTKRAVATKFVNKKLMKRDQVTHELGILQSLQHPLLVGLLDTFETPTSYILVLEMADQ--GRLLDCVVRWGS------L | . ..|.| |..|.|| |.|.| || | .. ... |. ||.. .|| .| |.|.|.. ... .|.|..|. | |.| .. |. . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF TEGKIRAHLGEVLEAVRYLHNCRIAHLDLKPENILVDESLAKPTIKLADFGDAVQLNTTYYIHQLLGNPEFAAPEIILGNPVSL-TSDTWSVGVLTYVLL .| .| . ....|. |.|. .| | ||||||||.|| .||..||| | || . . | |.. |||.. . . .| ||.|.. | .| PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML SGVSPFLDDSVEETCLNICRLDFSFPDDYFKGVSQKAKEFVCFLLQEDPAKRPSAALALQ-------EQWL .| || ... ..... |. ||.|.. .|| ||.|||.| ||| .|. CGYPPFP---QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | Trio.AA | Pkinase | 2796-3050 | 28 | 1.9e-65 | 228.56 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 2796-3050 Range on HMM: 1-293/293 Sequence Identity: 28% (84 aa) YSEVAELGRGRFSVVKKCDQKGTKRAVATKFVNKKLMKRDQVTH-----ELGILQSLQHPLLVGLLDTFETPTSYILVLEMADQG----RLLDCVV--RW | . .|.| |..|.|| ||| . || | ..|. | .. . |. |...|.|| | |.|.||..... .|.| .. | | | . | YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH GSL--TEGKIRAHLGEVLEAVRYLHNCRIAHLDLKPENILVD-ESLAKPTIKLADFGDAVQ--LNTTYYIHQLLGNPEFAAPEIIL-GNPVSLTSDTWSV |.. .| .. . ..|... |.|...| | ||||||||.| . ....|..||| | | . . . | |...|||.|. |.. . .| ||. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GVLTYVLLSGVSPFLDD------SVEETCLNICRLDFSFPDDYFKGVS-----------------QKAKEFVCFLLQEDPAKRPSAALALQEQWL |.. | .|.| || .. . . .| . ...|. .. .| . .|.|.. .|. ||.|||.|. .|| |. GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | Trio.AA | CAMK1 | 2796-3050 | 31 | 5.7e-60 | 172.98 | In-house | 1-276 (276) | Show / Hide |
Range on Protein: 2796-3050 Range on HMM: 1-276/276 Sequence Identity: 31% (87 aa) YSEVAELGRGRFSVVKKCDQKGT---KRAVATKFVN-KKLMKR------DQVTHELGILQS---LQHPLLVGLLDTFETPTSYILVLEMADQGRLLDCVV | |.||| ||.|..| .| | ....| | . || || ... |..|... ..|| . . . .|... . ||.| | |.| .| YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV RWGSLTEGKIRAHLGEVLEAVRYLHNCRIAHLDLKPENILVDESLAKPTIK--LADFGDAVQLNTTY-YIHQLLGNPEFAAPEIILG---NPVSLTSDTW |. || . | ..|.|| |.| |.| ||||||.| .|| .|||| . ... . . | |.. |||.. . | . . | | EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMW SVGVLTYVLLSGVSPFLDDS-VEETCLNICRLDFSFPDDYFKGVSQK-AKEFVCFLLQEDPAKRPSAALALQEQWL |.|| ||.|| | .|| |.. .| | . .. || ... .| . ||.|.. .| || ||.... .|. |. SIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI |
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| Kinase | Trio.AA | CAMK-Unique | 2796-3050 | 24 | 1.1e-59 | 195.67 | In-house | 1-363 (363) | Show / Hide |
Range on Protein: 2796-3050
Range on HMM: 1-363/363
Sequence Identity: 24% (88 aa)
YSEVAELGRGRFSVVKKCDQKGTKRAVATKFVNK---KLMKRDQ------------------VTHELGILQSLQHPLLVGLLDT----FETPT-------
| . .| | |..|..| . |. | | |.| . |..| . |..|.... || .. |.|. |....
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI
--------SYILVLEMADQGRLLDCVVRW--------------------GSLTE--GKIRAHLGEVLEAVRYLHNCRIAHLDLKPENILVDESLA-----
. .|.| .. | |.| ...| |...| .. ..|.|| |.|. | | |||.|||.| .|.
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH
--------KPTIKLADFGDAVQLN-TTYY--IHQLLGNPEFAAP--------------EIIL----GNPVSLTSDTWSVGVLTYVLLSGVSPFLDDSVE-
|||.||| ....| . .. | |...|| |.| . ..| ||.|| ||..| .|.| .|| .. .
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR
-------ETCLNICRLDF-SFPDDYFKG---VSQKAKEFVCFLLQEDPAKRPSAALALQEQWL
|. .|| |. .|. ... | .|| || || ... ||..| ||. .|. ||.
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
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| Kinase | Trio.AA | CAMKL | 2796-3050 | 27 | 4.3e-54 | 170.93 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 2796-3050 Range on HMM: 1-297/297 Sequence Identity: 27% (82 aa) YSEVAELGRGRFSVVKKCDQ-KGTKRAVATKFVNKKLMKRDQVTH----------------ELGILQSLQ---HPLLVGLLDTFETPTS------YILVL | . .||.| |..|| . . |.. || |...|| .. |.... | |...|. || . |....|||. . ||. YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM EMADQGR--LLDCVVRW----GSLTEGKIRAHLGEVLEAVRYLHNCRIAHLDLKPENILVDESLAKPTIKLADFGDAVQLNT-----TYYIHQLLGNPEF | .. | |.| .|. |...|. | ...|| |.|...|.| |.||||||.||. .||..||| . . . | |.. EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY AAPEIILG-NP--VSLTSDTWSVGVLTYVLLSGVSPFLDDSV------EETCLNICRLDFSFPDDYFKGVSQKAKEFVCFLLQEDPAKRPSAALALQEQW .||||..| | | || ||. |... | || ||.. | . .. .. || .. . .|| .| |||.. .. | MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW L . M |
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| Kinase | Trio.AA | PSK | 2796-3050 | 34 | 1.6e-53 | 169.2 | In-house | 1-258 (258) | Show / Hide |
Range on Protein: 2796-3050 Range on HMM: 1-258/258 Sequence Identity: 34% (89 aa) YSEVAELGRGRFSVVKKCDQKGTKRAVATKFVNKK-LMKRDQVTHELGILQSLQHPLLVGLLDTFETPTSYILVLEMADQGRLLDCVVRWGSLTEGKIRA | | |.| || | ... |.. | | |..| |. || || . || . |. ||| .|.||| | . | .| |. || . YDIKALIGKGSFSRVVRVEHRVTRQPYAIKMVETKCREGREFCENELNILRRVRHPYIIQLMEVFETQDRVYMVMEMATGGEMFDRIVAKGRFTERDATR HLGEVLEAVRYLHNCRIAHLDLKPENILVDESLAKPTIKLADFGDAVQLNTTYY--IHQLLGNPEFAAPEIILGNPVSLTSDTWSVGVLTYVLLSGVSPF | ||...|||| || | |||||| | .. | ||| | | . . | ||. |||. | | | | ||| .|.|.||. || VLQMVLDGMRYLHALRITHRDLKPENLLYYHPGNESKIMITDFGLAYQRKKSNDWMMKTTCGTPEYIAPEVLLRKPYTQSVDMWAVGVIAYILMSGIMPF LDDSVEETCLNICRLDFSFPDDYFKGVSQKAKEFVCFLLQEDPAKRPSAALALQEQWL ||. . | . ... .. ..||. ||.|. || .. .| .| |.. |. DDDCRTRLYRHILTGKYNYYGQPWPSVSHLAKDFIDKLLEINQGERMTASQAMKHPWV |
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| Kinase | Trio.AA | TyrKc | 2796-3049 | 21 | 8.6e-12 | -31.99 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 2796-3049 Range on HMM: 1-280/280 Sequence Identity: 21% (64 aa) YSEVAELGRGRFSVVKKCDQKGTKRAVATKFVNKKLMKRDQVTHELGILQSL--QHPLLVGLLDTFETP-------TSYILVLEMADQGRLLDCV-VRWG . .||.| | .| |. | . || | ... | .|. |. .| .|| .| |. .. . .|.| .. | |.| . . ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP SLTEGKIRAHLGEVLEAVRYLHNCRIAHLDLKPENILVDESLAKPTIKLADFGDAVQLNTT--------YYIHQLLGNPEF------AAPEIILGNPVSL |. . . . .||| .. | || |.||.| . |.| .||| . . || .. .. . ||| | . . KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT TSDTWSVGVLTYVLLS-GVSPFLD-----DSVEETCLNICRLDFSFPDDY-----FKGVSQKAKEFVCFLLQ---EDPAKRPSAALALQEQW || || ||. . ... | .| . | .| .. . . . .. | .| .| |||..||. . |.. KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF---VCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF |
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