Gene ULK4 (Human)

ULK4

Species: Human
Alias: FAM7C1, FLJ20574, DKFZp434E1822, ULK4, REC01035
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 3p21-p22,

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
ULK4.NA RNA Sugen Kinome 4425 None Fasta, JSON
ULK4.AA Protein Sugen Kinome 1275 None Fasta, JSON
ULK4.kin_dom Protein Kinase Domain Sugen Kinome 277 None Fasta, JSON

Protein domain

Protein domains of ULK4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase ULK4.AA ULK 4-280 26 6.1e-85 288.5 In-house 1-324 (324) Show / Hide 
Range on Protein: 4-280
Range on HMM: 1-324/324
Sequence Identity: 26% (89 aa)

FILYEEIGRGSKT-VVYKGRRKGT---INFVAILCTDKC----------------KRPEITNWVRLTREIKHKN--IVTFHEWYETS--NHLWLVVELCT
..| ...| ||   .||||| | |     .||. . ||.                .     ....   |.||.|  || ...|.|||  |......|.| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGSLKTVIAQDENLPEDV----------VREFGIDLISGLHHLHKLGILFCDISPRKILLEGP------------GTLKFSNFCLAKVEGENLEEFFALV
|| |.. | .. .||| .          ...| .....|. .||| .|  .|| |  ||.  .            |.|| . |..||.  .| .| . . 
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

AAE-EGGGDNGENVLKKSMKSRVKGSPVYTAPEVVR----GADFS-ISSDLWSLGCLLYEMFSGKPPFFSESISELTE------------KILCED-PLP
 .  |      .         |.||.| | ||...     . ... . .|.|||||..|||  ||.||||  .... .            .|. .. |..
TCVNE------K---------RIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQ

PIPKDSSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQHSFW
. ... . || |.....|. ..||.|. .| .|. ...| ..
FPKPP-KDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase ULK4.AA ULK 4-280 25 1.9e-84 286.89 In-house 1-329 (329) Show / Hide 
Range on Protein: 4-280
Range on HMM: 1-329/329
Sequence Identity: 25% (87 aa)

FILYEEIGRGSKTVVYKGRRKGT------INFVAILCTDKCKRPE-----------ITNWVRLTREIK----HKN----IVTFHEWYETS--NHLWLVVE
..| ...| ||  .||||| | |      . .. ... .|... .           ..|.... ...|    |||    || ...|.|||  |......|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LCTGGSLKTVIAQDENLPEDV----------VREFGIDLISGLHHLHKLGILFCDISPRKILLEGP------------GTLKFSNFCLAKVEGENLEEFF
.| || |.. | .. .||||.          ...| .....|. .||| .|  .|| |  ||.  .            |.|| . |..||.  ....| .
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

ALVAAE-EGGGDNGENVLKKSMKSRVKGSPVYTAPEVVR----GADFS-ISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCED-------------
 ....  |      .         |..|.| | ||...     . ...   .|.|||||..|||  |||||..  .... ..|. .              
MMMTCVNE------K---------RLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKK

PLPPIPKDSSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQHSFW
  . .||| . |. |.....|. ..||.|. .| .|. |..| ..
QPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase ULK4.AA S_TKc 4-280 25 3.3e-54 187.34 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-280
Range on HMM: 1-231/231
Sequence Identity: 25% (75 aa)

FILYEEIGRGSKTVVYKGRRKGTINFVAILCTDKCKRPEITNWVRLTREIKHKNIVTFHEWYETSNHLWLVVELCTG--GSLKTVIAQDEN------LPE
. . ..||.|.  .|||.| |.|   ||| . .      | . ... .. .|.|||........ .||..| |.| |  |.|...| .         .||
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE

DVVREFGIDLISGLHHLHKLGILFCDISPRKILLEGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSMKSRVKGSPVYTAPEVVRGAD
 ..| .   ....| ..|..||. .|. |  |||    ..| . | ||..                               . . |.| | ||||.    
-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------------------------TTFCGTPWYMAPEVL---G

FSI-SSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCEDPLPPIPKDSSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQ-------HSFW
..  ..| ||.||.||||..|.|||    . .. .||.                 |..........||.||.||.|   .||       | . 
YGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase ULK4.AA CAMK 9-280 19 4e-45 142.92 In-house 1-425 (425) Show / Hide 
Range on Protein: 9-280
Range on HMM: 1-425/425
Sequence Identity: 19% (85 aa)

EIGRGSKTVVYKGRRKGTI------------NFVAILCTDKCKRPEIT-------------------------NWVRLTREIK-------------HKNI
..||||  .|.....| |               |||   || | .. .                         .  .. |||.             |.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VTFHEWYE------------TSNH--------LWLVV---ELCTGG----SLKTVIAQDEN---------------LPEDVVREFGIDLISGLHHLHKLG
. ..|.||            | ..        ...|    |.|.||     |   | . ..               ..|. .| .   ..|..|..|...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

ILFCDISPRKILLEGP-----------------GTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKK--------SMKSRVKGSPVYTA-PEV
|  .|. |  |||                    ...| . | .|..  .. ..|.         ...|| . ..         . . . |.| | | |||
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSD------YKGGE-M-HNQWTTPTEGQKMKTFCGTPEYMAAPEV

VRG-------------ADF-SISSDLWSLGCLLYEMFSGKPPFFSE-------------SISELTEKIL-CEDP-LPPIPKDSS----------------
..|              .  . ..| ||.|..|| | .|.||| ..             ...|| |||. ..    ||  ...|                
LNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFH

RPKASSDFINLLDGLLQRDPQKRLTWTRLLQHSFW
. . | . ..|. ..||.||.||.| .  |.| . 
H-FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase ULK4.AA Ciliate-E2 4-280 19 9.9e-43 144.5 In-house 1-365 (365) Show / Hide 
Range on Protein: 4-280
Range on HMM: 1-365/365
Sequence Identity: 19% (78 aa)

FILYEEIGRGSKTVVYKGRR-----------------------KGTINFVAILCTDKCKRPEITNWVRLTREIK----------------HKNIVTFHEW
... . ||.|.  .|||...                       | .|...|. .  | .  .| .  .. |||.                |.||. ..|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YE--TSNHLWLVVELCTGGSLKTVIA------------QDENLPEDVVREFGIDLIS---------------GLHHLHKLG-ILFCDISPRKILLEGPGT
..  . |.. || |.| ||.|.  |             . ... |  ....   ...               .|..||. . |.  || |  ||.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

LKFSNFCLAK------------VEGENLEEFF----------ALVAAEEGGGDNGENVLKKSMKSRVKGSPVYTAPEVVRGAD---------FSISSDLW
.| . | |.|            .. ... . .          ..             ...  |  .. |.| | |||...| .          . ..|.|
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQ-------------IIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIW

SLGCLLYEMFSGKPPFFSESISELTEKILCEDPLPPIPKDSS----------RPKASSDFINLLDG----LLQRDPQKRLT-WTRLLQHSFW
|||..|||| .|||||       . ... |.  .|.  ...             | | . ..|.      .||.||.||.| |  .|.| . 
SLGVILYEMLFGKPPF-------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase ULK4.AA RSK 52-280 23 3.7e-39 136.43 In-house 56-278 (278) Show / Hide 
Range on Protein: 52-280
Range on HMM: 56-278/278
Sequence Identity: 23% (60 aa)

EIK-HKNIVTFHEWYETSNHLWLVVELCTGGSLKTVIAQDEN---LPEDVVREFGIDLISGLHHLHKLGILFCDISPRKILLEG---PGTLKFSNFCLAK
... |..||| |. ..|  .|.|. |.| || | | . . .    . || ...    ... . |||..|| . |. |  ||..    .|..| . | ..|
RCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCK

VEGENLEEFFALVAAEEGGGDNGENVLK-KSMKSRVKGSPVYTAPEVVR----GADFSISSDLWSLGCLLYEMFSGKPPFFS---ESISELTEKILCED-
                         ... ...     ..  | |||...    .   . . |.||||.|.|||..|.||| .   .. .|. ..|.  . 
QF-----------------------RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKF

-PLPPIPKDSSRPKASSDFINLLDGLLQRDPQKRLT-----WTRLLQHSFW
 .  |..     .. | .. .|. ..|.|||.|||.       ...||...
SLTMPNW-----QYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase ULK4.AA AGC 181-280 27 5.7e-37 91.88 In-house 267-395 (395) Show / Hide 
Range on Protein: 181-280
Range on HMM: 267-395/395
Sequence Identity: 27% (36 aa)

G--SPVYTAPEVVRGADFSISSDLWS--LGCLLYEMFSGKPPFFSES----------ISELTEKIL------CEDPLPPIPKDS---SRPKASSDFINLL
|  .| | |||..     . . | ||  ||||.||| .|.|||....            |. .||.       ...  | |.|.    ... |..  .|.
GPCTPEYMAPEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLI

DGLLQRDPQKRLT----------WTRLLQHSFW
 .||..|| |||.             . .| . 
KKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase ULK4.AA MSK 54-281 25 7.8e-37 122.04 In-house 59-277 (277) Show / Hide 
Range on Protein: 54-281
Range on HMM: 59-277/277
Sequence Identity: 25% (64 aa)

KHKNIVTFHEWYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKLGILFCDISPRKILLEGP---GTLKFSNFCLAKVEGEN-
.|.|||. |. . .. |..|| |.|.|| | | | . |.  |. .|.    |.. . |.|..|| . |. |  ||...    |..| . | .|.   .. 
QHPNIVNLHYAFQDQCHTYLVMEYCNGGELFTHIRKREHFDESECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHVKLIDFGFARLFPQDE

LEEFFALVAAEEGGGDNGENVLKKSMKSRVKGSPVYTAPEVVR----GAD-FSISSDLWSLGCLLYEMFSGKPPFF--SESIS-------ELTEKILCED
 .  .                          ..  | |||..|    .   .. . |.|||| .||.| .|. ||   .....       |.  .|. ..
EWRMKS-----------------------PCFTLHYMAPEMLRRGYAQDGGYDEACDWWSLGVILYTMLTGQVPFQQNEDDRQHSCNSHHEIMKRICKGE

PLPPIPKDSSR----PKASSDFINLLDGLLQRDPQKRLTWTRLLQHSFWK
.       | .     ..| |. .|. .||..||.|||.   |..|. ||
F-------SFPGMAWQNMSPDAKDLIQWLLTKDPKKRLGMNDLRAHE-WK
Kinase ULK4.AA Ciliate-E2-Unclassified 4-280 19 1.5e-35 120.76 In-house 1-352 (352) Show / Hide 
Range on Protein: 4-280
Range on HMM: 1-352/352
Sequence Identity: 19% (73 aa)

FILYEEIGRGSKTVVYKGRRKGT-------INFVAILCTDKCKRPEITNWVRLTREIKHKN----------------------IVTFHEWYETSNHLWLV
... . ||.|.  .||| ..| .       .. ... . .| .. .. . ..   |.. |.                      || .... .. ... .|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

VELCTGGSLKTVIAQDEN-----------------LPEDVVR-----EFGIDLISGLHHLHKLG-ILFCDISPRKILLEGPG---TLKFSNFCLAKVEGE
 |.| ||.|.  | . ..                 ..|  ..      .   ...|| .||. . |.  || |  ||.   |    .| . | ..|  ..
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

N-------LEEFFALVAAEEGGGDNGENVLKKSMKSRVKGSPVYT----APEVVRGADFS----ISSDLWSLGCLLYEMFSGKPPFFSESISE-------
|       .               .  ...|. | . . |.| |     |||| .|   .    ...| ||||..||||  |..||....  .       
NNNCDTNQQ---------------QKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQ

---------LTEKILCEDPLPPIPKD----SSRPKASSDFIN-LLDGLLQRDPQKRLTWTRLLQHSFW
         | ..|.  ..  |  .        ..   |||| ||  .|. .| ||.|.  .|.| . 
WINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase ULK4.AA Pkinase 181-280 28 3e-32 115.12 Pfam 173-293 (293) Show / Hide 
Range on Protein: 181-280
Range on HMM: 173-293/293
Sequence Identity: 28% (35 aa)

GSPVYTAPEVVR-GADFSISSDLWSLGCLLYEMFSGKPPFFSE------SISELTEKILCEDPLPPIPKDSSRP--------------KASSDFINLLDG
|.| | ||||.| | . . ..| ||.||.||||..|.||| ..      .  .. ..|.. ..  ..|...|..              ..|.... ....
GTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKW

LLQRDPQKRLTWTRLLQHSFW
.|..||.||.|.. .||| ..
CLCKDPKKRPTAEQILQHPWF
Kinase ULK4.AA STE 174-280 25 3.1e-25 86.15 In-house 218-359 (359) Show / Hide 
Range on Protein: 174-280
Range on HMM: 218-359/359
Sequence Identity: 25% (37 aa)

SMKSRVKGSPVYTAPEVVRG------ADFSISSDLWSLGCLLYEMFSGKPPFFSESIS----ELTEKILCED----------PLPPIPKDSSRP------
..   . |.| . ||||...       . ....| |||||.. ||  ||||.. ..      . . .. ...          | ||.| . | .      
QKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYG

--------KASSDFINLLDGLLQRDPQKRLTWTRLLQ--HSFW
        | |..|.. ..  ||.||.|| | . ||.  |.| 
GSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase ULK4.AA Fused 179-280 40 4.6e-25 82.84 In-house 157-251 (251) Show / Hide 
Range on Protein: 179-280
Range on HMM: 157-251/251
Sequence Identity: 40% (41 aa)

VKGSPVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCEDPLPPIPKDSSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQHS
.|| | | ||| |    .    |.||||| ||| . |.|||.  ||  |   |. .|   |          .| . | | ||| .||..|..|. || | 
IKGTPLYMAPELVEEQPYDHHADMWSLGCILYELMVGQPPFCANSIFHLVSMIKHDDVKWPS-------TITSCCRNFLQGLLTKDPRHRISWPQLLCHP

FW
| 
FV
Kinase ULK4.AA Pkinase 4-122 25 4e-23 82.86 Pfam 1-134 (293) Show / Hide 
Range on Protein: 4-122
Range on HMM: 1-134/293
Sequence Identity: 25% (34 aa)

FILYEEIGRGSKTVVYKGRRKGTINFVAILCTDKCKRPEITN-------WVRLTREIKHKNIVTFHEWYETSNHLWLVVELCTGG----SLKTVIA--QD
. . . ||.||  .|||...|||   ||. . .|... .  .        ... ....|.|||....|.|...|...| |.| ||    .|...|   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

ENL--PEDVVREFGIDLISGLHHLHKLGILFCDI
 ..  .|.... .   ...|| ..|. ||. .|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDL
Kinase ULK4.AA STE 4-117 18 1.2e-18 62.56 In-house 1-173 (359) Show / Hide 
Range on Protein: 4-117
Range on HMM: 1-173/359
Sequence Identity: 18% (32 aa)

FILYEEIGRGSKTVVYKGRRKG---------------TINFVAILCTD--------------------KCKRPEITNWVRLTREIK--HKNIVTFHEWYE
. . |.||.|.  .|||....                | ...||   .                    . .. .| . ... .. .  |.|||...  |.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TS-------NHLWLVVELCTGGSLKTVIA------QDEN--------LPEDVVREFGIDLISG-LHHLHKLGI
         ..||.. |.. ||||  .|       .. |        .||.... .  ... | |..||...|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHI
Kinase ULK4.AA TyrKc 4-280 21 6.7e-13 -14.07 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-280
Range on HMM: 1-280/280
Sequence Identity: 21% (65 aa)

FILYEEIGRGSKTVVYKGRRKGTINFVAI--LCTDKCKRPEITNWVRLTREI--KHKNIVTFHEWYETS-------NHLWLVVELCTGGSLKTVIAQDEN
  | ...|.|   .||||. |     ||.  |  |.  | .. .  |. ...  .|.||| ..    ..         |..|.|.. .|.||  .   ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-LPEDVVREFGIDLISGLHHLHKLGILFCDISPRKILLEGPGTLKFSNFCLAKVEGEN-LEEFFALVAAEEGGGDNGENVLKKSMKSRVKG-SPV-YTAP
 |. .   .| ..  .|  .||. ..   |.  | .|.  ..| | | | |..  ..   .                . . .|. ..  |.  |.  .||
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-------------ESKDYYRKKEHKGGKTMLPIRWMAP

EVVRGADFSISSDLWSLGCLLYEMFS-GKPPFFS-----ESISELTEKILCEDPLPPIPKD---SSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQHSF
|. .   |.. || || | ...|.|. |..|         | .|. |..   . .|. | |   |. . ....  ..     ..|| .| | . .  |..
ECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF-VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HEC

W
.
F
Kinase ULK4.AA AGC 50-122 20 2e-12 26.92 In-house 84-181 (395) Show / Hide 
Range on Protein: 50-122
Range on HMM: 84-181/395
Sequence Identity: 20% (20 aa)

TREIK--HKNIVT-FHEWYETSNH--LWLVVELCT---------GG-SLKTVIA---QDENLPEDVVREFGID-------LISGLHHLHK-LGILFCD-I
. . |  | .||   |  ... .|  | .| |..          ||  | . .    .   ..|...| .          ....|..||. .||   | .
P-I-KSHHPFIVKILHYSFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYL
Kinase ULK4.AA Fused 4-143 31 6e-12 37.1 In-house 1-144 (251) Show / Hide 
Range on Protein: 4-143
Range on HMM: 1-144/251
Sequence Identity: 31% (45 aa)

FILYEEIGRGSKTVVYKGRRKGTINFVAILCTDKCKRP--EITNWVR---LTREIKHKNIVTFHEWYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVV
.   | .| ||   |||.|||     |||    |  |   |  |  |     |...| .|.   . .||   .  | .    . |  .   |  .||. |
YHVSEMVGQGSFGCVYKARRKYDSKVVAIKFIPKRGRSDKELKNLRRECEIMRRMHHPHIIHMIDSFETDKEVVVVTDYAE-MELHQYLEYDGKMPEEQV

REFGIDLISGLHHLHKLGILFCDISPRKILLEGPGTLKFSNFCLA
|.    |.| |  ||   ||  |. |  |||.  .  |   | .|
RRIACHLVSALYYLHSHRILHRDMKPQNILLDKNMHIKLCDFGFA
Kinase ULK4.AA Pkinase_Tyr 186-243 33 6.9e-07 23.94 Pfam 181-240 (270) Show / Hide 
Range on Protein: 186-243
Range on HMM: 181-240/270
Sequence Identity: 33% (20 aa)

TAPEVVRGADFSISSDLWSLGCLLYEMFS-GKPP-FFSESISELTEKILCEDPLPPIPKD
.|||. .   |.. || || | |..|.|. |. | .   | .|. |.|  .    |.|..
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPEN
Kinase ULK4.AA Pkinase_Tyr 51-85 20 0.012241 9.56 Pfam 58-96 (270) Show / Hide 
Range on Protein: 51-85
Range on HMM: 58-96/270
Sequence Identity: 20% (8 aa)

REI-KHKNIVTFHEWYE-TSNH--LWLVVELCTGGSLKT
... .|.||| ..      . .  ...|.|.. .|.|..
KQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD
Kinase ULK4.AA Pkinase_Tyr 4-25 36 1.280573 2.72 Pfam 1-22 (270) Show / Hide 
Range on Protein: 4-25
Range on HMM: 1-22/270
Sequence Identity: 36% (8 aa)

FILYEEIGRGSKTVVYKGRRKG
 .. ...|.|.  .||||. ||
ITFGKKLGEGAFGEVYKGTWKG