Gene DDB0185224 (Slime mold)

DDB0185224

Species: Slime mold
Alias: DDB0185224, pkaD, PK1, DdisK017, GPK1
External Links: DictyBase Link ,
Annotation:

Classification

Group: AGC
Family: PKA

Sequence

Name Sequence Type Origin Length Description Download
DDB0185224.AA Protein None 714 None Fasta, JSON
DDB0185224.kin_dom Protein Kinase Domain None 256 None Fasta, JSON

Protein domain

Protein domains of DDB0185224.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0185224.AA PKA 334-589 46 5.2e-160 537.88 In-house 1-263 (263) Show / Hide 
Range on Protein: 334-589
Range on HMM: 1-263/263
Sequence Identity: 46% (124 aa)

FNFYGSLGSGSFGTAKLCRHRGSGLFFCSKTLRRETIVHEKHKEHVNNEINIMLNISHPYIV-KTYSTFNTPTKIHFIMEYAGKKDLFHHLRANKCFTEQ
|... .||.||||...||||..|| ....|.|....||..|..|||.||.||..||.||.|| |.|.||.........|||......|..||....|...
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

TTKLIVA-EIVLAIEYLHAENIIYRDLKPENILIDEKGHIKLTDFGFSKKTVGGKNTSSVCGTFDYMAPEILNSSNGHGKPVDWWALGVVVYELVTGKLP
..|...| .||||.||||..|||||||||||||||..||||.|||||.||...  .|...|||..|.||||..|.|||||.|||||||...||...|. |
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPP

FSNS---KESLLNRKADFQLIFQNSYLSDE--IKDFIFQLLSVDPSKRLGTFDS--CSIRNHKWF
|...   . .. ........ |.... ||.  .||.|..||.||..||.|....  ..|.|||||
FYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase DDB0185224.AA AGC 334-589 28 4.5e-150 391.08 In-house 1-395 (395) Show / Hide 
Range on Protein: 334-589
Range on HMM: 1-395/395
Sequence Identity: 28% (113 aa)

FNFYGSLGSGSFGTAKLCRHR------GSGLFFCSKTLRRET-IVHEK--HKEHVNNE------------INIMLNIS----------HPYIVK-TYSTF
|.|.  .| ||||.  |.|..      ..| ..  | |. .. ||  |    ||...|             ||. ...          ||.|||  ...|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

NTPTK--IHFIMEY---------AGKK-DLFHHLR---ANKCFTEQTTKLIVAE-------IVLAIEYLHA-ENIIYRD-LKPENILIDEKGHIKLTDFG
 ....  ..|.|||          |   .||.||.    ...|.|.... . ||       ||||.||||   .||.|| |||||||.||.|||||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

FSKKTV---------------------------------------------------GGKNTSSVCG--TFDYMAPEILNSSNGHGKPVDWWA--LGVVV
..|. .                                                   ... |.. ||  | .|||||||     .||..|||.  ||.. 
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLM

YELVTGKLPFSNS-----------KESLLNRKA------DFQLIFQN---------SYLSDEIKDFIFQLLSVDPSKRLGTFD-------SCSIRNHKWF
||..||. ||..            .. . ..         ... | .         ...|.| ||.| .|| .||.||||. .          |.||.||
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase DDB0185224.AA Pkinase 334-589 31 2.9e-105 360.83 Pfam 1-293 (293) Show / Hide 
Range on Protein: 334-589
Range on HMM: 1-293/293
Sequence Identity: 31% (94 aa)

FNFYGSLGSGSFGTAKLCRHRGSGLFFCSKTLRRETIVHEKHKEHVN-NEINIMLNISHPYIVKTYSTFNTPTKIHFIMEYAGKK----DLFHHLR--AN
. . . .||||||. ..|.|.|.|  .. |....... ..|...|.. .|| ||....||.||..| .| ....|...|||...     |||....  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KCF--TEQTTKLIVAEIVLAIEYLHAENIIYRDLKPENILIDEKGHI----KLTDFGFSKK--TVGGKNTSSVCGTFDYMAPEILNSSNGHGKPVDWWAL
.||  .|.. | .. .|. ..||.|...||.|||||||||||..|||    |..|||..|.  .  .  ....||| .|||||........|..||.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVVVYELVTGKLPFSNS-------KESLLNRKADFQLIFQNSYLS--------------------DEIKDFIFQLLSVDPSKRLGTFDSCSIRNHKWF
|...||...|..||...       .  ...|. . .| |. ....                    .| ||||  .| .||.||..      | .|.||
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT---AEQILQHPWF
Kinase DDB0185224.AA S_TKc 334-589 33 6.3e-100 339.19 SMART 1-231 (231) Show / Hide 
Range on Protein: 334-589
Range on HMM: 1-231/231
Sequence Identity: 33% (91 aa)

FNFYGSLGSGSFGTAKLCRHRGSGLFFCSKTLRRETIVHEKHKEHVNNEINIMLNISHPYIVKTYSTFNTPTKIHFIMEYAGK--KDLFHHLRANKC---
. .   .|.|.||. ..|||...|  .  | ..          ||. .||.|. .  ||.||| | .| . ......|||..    |||.... ...   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FTEQTTKLIVAEIVLAIEYLHAENIIYRDLKPENILIDEKGHIKLTDFGFSKKTVGGKNTSSVCGTFDYMAPEILNSSNGHGK-PVDWWALGVVVYE
   |.| ... ....|..|.||.|  .||.|||||||||.||  |||..|||....       ...||| .|||||.|    |.|| ..|||..|...||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE

LVTGKLPFSNSKESLLNRKADFQLIFQNSYLSDEIKDFIFQLLSVDPSKRLGTFDSCS----IRNHKWF
...|. ||.           . |..|..   |.| |||| ..| .||.||..  .       |..| ||
MLCGYPPFP-----------QMQMMFKKIG-SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DDB0185224.AA AktR 334-589 41 2e-95 323.31 In-house 1-268 (268) Show / Hide 
Range on Protein: 334-589
Range on HMM: 1-268/268
Sequence Identity: 41% (110 aa)

FNFYGSLGSGSFGTAKLCRHR-GSGLFFCSKTLRRETIVHEKHKEHVNNEINIML-NISHPYIVKTYSTFNTPTKIHFIMEYAGKKDLFHHLRANKCFTE
| .|  ||.| ||.  |....  .. ..  | .. ..|. .. ..|. .| |||   ..|| ||| . .| | .|. |||||    .||.||. .| |.|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

QTTKLIVAEIVLAIEYLHAE-NIIYRDLKPENILIDEKGHIKLTDFGFSK---KTVGGKNTSSVCGTFDYMAPEILNSSNGHGKPVDWWALGVVVYELVT
.... . |.|.||.|||| . |||||||||||||.|| ||.|.|||| ||   . .    . |.|||. |||||... . ||.|.|||||.|...||.||
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GKLPFSNSKESLLNRKADFQL---IFQNSYLSDEIKDFIF-QLLSVDPSKRLG--TFDSCSIRNHKWF
|  || ...   .. | ...    . ..||.|.. ||.|  .||  .| ||||  . .   |..|.||
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase DDB0185224.AA SGK 334-589 36 6.7e-88 271.49 In-house 1-283 (283) Show / Hide 
Range on Protein: 334-589
Range on HMM: 1-283/283
Sequence Identity: 36% (103 aa)

FNFYGSLGSGSFGTAKLCRHRGS------------------GLFFCSKTLRRETIV-------HEKHKEHVNNEI-NIMLNISHPYIVKTYSTFNTPTKI
| |   .| ||||   . .| .                   . |. .| |....|.         |.  |.  |  .|. |..|| ||.    | |..| 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

HFIMEYAGKKDLFHHLRANKCFTEQTTKLIVAEIVLAIEYLHAENIIYRDLKPENILIDEKGHIKLTDFGFSK-KTVGGKNTSSVCGTFDYMAPEILNSS
 | |.|.   ..| ||.  |.| |   .  .||||.|.||||  .|||||||||||| | .||..||||| .| .    . |.. |||  |.|||.|.  
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLR-K

NGHGKPVDWWALGVVVYELVTGKLPFSNSKESLLNRKADFQLIFQNSYLSDEIKDFIFQLLSVDPSKRLGTF-DSCSIRNHKWF
 .|.. |||| || | ||. .|. || .   ...  .   | .    . | . .| | .||  ||.|||||  |.  |.|| .|
QPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase DDB0185224.AA RSK 334-589 40 1.3e-87 297.41 In-house 1-278 (278) Show / Hide 
Range on Protein: 334-589
Range on HMM: 1-278/278
Sequence Identity: 40% (112 aa)

FNFYGSLGSGSFGTAKLCRHRGSGLFFCSKTLRRETIVH-EKHKEHVNNEINIMLNIS-HPYIVKTYSTFNTPTKIHFIMEYAGKKDLFHHLRANKC---
    | .| |.. . . |.|. .|  .  | |.. .||  .|  .|.  |.||.. .  || ||. . .| |..|.. ||||    .|| ||.  |.   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FTEQTTKLIVAEIVLAIEYLHAENIIYRDLKPENILIDE---KGHIKLTDFGFSKK-TVG-GKNTSSVCGTFDYMAPEILN---SSNGHGKPVDWWALGV
|.| . . . ||||||.|.||   ||.||||||||| |.    ||||||||||.|.     .. | . |.| .|||||.|.     .||.| .||| |||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

VVYELVTGKLPFSN----SKESLLNR--KADFQLIFQ-NSYLSDEIKDFIFQLLSVDPSKRLG--TFDSCSIRNHKWF
. ||. ||..|| .    ... ...|  |..| | .  ..|||.| ||.| ..| .||.||||    |   |..|.||
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase DDB0185224.AA Akt 334-589 41 1.9e-87 279.63 In-house 1-264 (264) Show / Hide 
Range on Protein: 334-589
Range on HMM: 1-264/264
Sequence Identity: 41% (112 aa)

FNFYGSLGSGSFGTAKLCRHRGSGLFF-CSKTLRRETIVHEKHKEHVNNEINIMLNISHPYIVKTYSTFNTPTKIHFIMEYAGKKDLFHHLRANKCFTEQ
|.|   ||.||||   |..   .. ..   | |. . |.  ...||.  | ||  .. ||.||. .  | |..|. |.|.|..  .|| ||.  . |.|.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

TTKLIVAEIVLAIEYLHAENIIYRD-LKPENILIDEKGHIKLTDFGFSKKT-VGG-KNTSSVCGTFDYMAPEILNSSNGHGKPVDWWA-LGVVVYELVTG
...  .|||.||||.||  |||||| |||||||.|..|||.||||| .|.  .     | ..|||  |.||||||  |||.|.||||. ||.| ||. .|
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNG-NGHTKAVDWWGSLGCVMYEMMCG

KLPFSNSKESLLNRKADFQLIFQN-------SYLSDEIKDFIFQLLSVDPSKRLG-TFD-SCSIRNHKWF
 .|| | .    ...  |..|...       ...|.| ||.| .||. ||.|||| ...    |..| ||
RPPFYN-Q----DHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase DDB0185224.AA CAMK 339-589 21 5.9e-80 257.19 In-house 1-425 (425) Show / Hide 
Range on Protein: 339-589
Range on HMM: 1-425/425
Sequence Identity: 21% (93 aa)

SLGSGSFGTAKLCRHRGSG------------LFFCSKTLRRETIV-------------------------HEKHKEHVNNEINIMLN-------ISHPYI
 ||.||||. |||.|. ..              .  | . .. .                           .| .. | .||.|| .       ..|| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKTYSTFN------------TPTK--------IHFIM---EYAGKK----DLFHHLRANKC---------------FTEQTTKLIVAEIVLAIEYLHAEN
.| | ..             | .|        ....|   ||.       ||| ......|               |||. .. ..  |. |..|.|  |
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIYRDLKPENILIDEK-----------------GHIKLTDFGFSKKTVG------------------------GKNTSSVCGTFDYMA-PEILNS-----
|. |||||||||.|..                 . ||..||||..|  .                        |.  . .|||  ||| ||.||.     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------SNGHGKPVDWWALGVVVYELVTGKLPFSNSKESL----------------LNRKADFQLI----------------------FQNSYLSDEI
          ..|...| |..||. | ...|..||  ....                   .|.... .                      |.. ..|.| 
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH-FVSQEC

KDFIFQLLSVDPSKRLGTFDSCSIRNHKWF
||.| ..| |||.||.   .   . ||.|.
KDLIRKMLQVDPEKRMTIEQ---CLNHPWM
Kinase DDB0185224.AA Ciliate-E2 334-589 26 4.5e-76 259.05 In-house 1-365 (365) Show / Hide 
Range on Protein: 334-589
Range on HMM: 1-365/365
Sequence Identity: 26% (100 aa)

FNFYGSLGSGSFGTAKLCRHRGSG-----------------------LFFCSKTLRRETIVHEKHKEHVNNEIN----------IMLNISHPYIVKTYST
..|   .|.|.||. ..|...  .                        ..  |...   | . | ..|...|||          |. ...||.|.| | .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FN--TPTKIHFIMEYAGKKDLFHHLR------------ANKCFTEQTTKLIVAEIVL---------------AIEYLHAEN-IIYRDLKPENILIDEKGH
|   . ..| ..|||.  .|||....            . |.|||.  | | ..|.                |.|||| .| ||.||.||||||.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

IKLTDFGFSK----------------KTVGGKN-----------------TSSVCGTFDYMAPEILNS--------SNGHGKPVDWWALGVVVYELVTGK
||..|||.||                .    ||                 . ..|||  ||||||||.        ..|... .|.|.|||. ||...||
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

LPFSNSKESLLNRKADFQLIF-------------QNSYLSDEIKDFIFQ----LLSVDPSKRLGTFDSCSIRNHKWF
.||    .  .. | ||.  .              . ..|.| ||.| .    .| .||.||..  .   | ||.||
PPF---QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT--GWEQILNHPWF
Kinase DDB0185224.AA Ciliate-E2-Unclassified 334-589 28 4.8e-76 258.95 In-house 1-352 (352) Show / Hide 
Range on Protein: 334-589
Range on HMM: 1-352/352
Sequence Identity: 28% (101 aa)

FNFYGSLGSGSFGTAKLCRHRGSGLFFCSKTLRRETIVHEKHKEHVN---------NEIN-------------IMLNISHPYIVKTYSTFNTPTKIHFIM
...   .|.|.||. ..|.|.  ....  |..    |.. | .....         |...             |.||. ||.||| . .|..  .| ..|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYAG-----------------KKDLFHHLRANKCFTEQTTK-----LIVAEIVLAIEYLHAEN-IIYRDLKPENILIDEKG---HIKLTDFGFSK-----
||.                  ..||||... .|.|||| .|      . |.|....|||| .| ||.||.||||||.|..|   .||..|||.||     
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

-----------KTVGGKNTSSVCGTFDYM----APEILNS-SNGHG--KPVDWWALGVVVYELVTGKLPFSNSKESLLN-----------RKADFQLIFQ
           .    ......|||  ||    |||.| .  ..|   . .|.|.|||. ||...|..||.  ..   .           ||  .| |.|
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

N-------------SYLSDEIKDFIF----QLLSVDPSKRLGTFDSCSIRNHKWF
.               .|.| ||||     ..| ..|.||. ||.   | || ||
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRI-TFE--QILNHPWF
Kinase DDB0185224.AA MSK 334-589 33 1e-71 241.7 In-house 1-277 (277) Show / Hide 
Range on Protein: 334-589
Range on HMM: 1-277/277
Sequence Identity: 33% (95 aa)

FNFYGSLGSGSFGTAKLCRHRGSGLFFCSKTLRRETIVH-EKHKEHVNNEINIMLNI-SHPYIVKTYSTFNTPTKIHFIMEYAGKKDLFHHLRANKCFTE
    | .| |.|.. . |.|. .|. .  | |.  |.|   | .||.  |. . . . .||.||. . .| .... . .|||.    || |.|  . |.|
LKVLGTGGYGKFFICRKCVHHDTGKLYAMKILSKATVVQKRKTAEHTQTERQCLEMCQQHPNIVNLHYAFQDQCHTYLVMEYCNGGELFTHIRKREHFDE

QTTKLIVAEIVLAIEYLHAENIIYRDLKPENILIDEK---GHIKLTDFGFSKKTVGG--KNTSSVCGTFDYMAPEILNS---SNG-HGKPVDWWALGVVV
.    |..|.|.|....| . ||.||||||||| |..   ||.||.||||.. .. .  . . | |.| .|||||.|.    ..| ... .||| |||. 
SECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRGYAQDGGYDEACDWWSLGVIL

YELVTGKLPFS----------NSKESLLNRKADFQLIFQ---NSYLSDEIKDFIFQLLSVDPSKRLGTFDSCSIRNHKWF
|.. ||. ||           ||   .  |    .  |.    .  | . ||.| .|| .||.||||. |   .| | | 
YTMLTGQVPFQQNEDDRQHSCNSHHEIMKRICKGEFSFPGMAWQNMSPDAKDLIQWLLTKDPKKRLGMND---LRAHEWK
Kinase DDB0185224.AA TyrKc 334-589 21 2e-14 10.42 SMART 1-280 (280) Show / Hide 
Range on Protein: 334-589
Range on HMM: 1-280/280
Sequence Identity: 21% (65 aa)

FNFYGSLGSGSFGTAKLCRHRGSGLFFCS---KTLRRETIVHEKHKEHVNNEINIMLNI--SHPYIVKTYSTFNTP-------TKIHFIMEYAGKKDLFH
  .   ||.| ||.  ... .           |.|. ..      .|   .|..|| ..  .|| ||. |    ..         .  .|||. . || .
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

HLRANKC-FTEQTTKLIVAEIVLAIEYLHAENIIYRDLKPENILIDEKGHIKLTDFGFSKKTVGG-------KNTSS----VC---GTFDYMAPEILNSS
.||...  .. ..   .   |    ||||  |.| |||   |.|..|....| .||| |..   .       .  ..     .        |||| .   
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NY

NGHGKPVDWWALGVVVYELVT-GKLPFSN------SKESLLNRKADFQLIFQNSY--------LSDEIKDFIFQLLSVDPSKRLGTFDSCSIRNHKWF
.      | |. ||. .|. | |. | ..      | . ....  .     |  .         .||. . . |    ||..|  ||  .    |. |
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRP-TFSEI----HECF
Kinase DDB0185224.AA Pkinase_Tyr 410-477 33 0.003649 11.34 Pfam 85-156 (270) Show / Hide 
Range on Protein: 410-477
Range on HMM: 85-156/270
Sequence Identity: 33% (24 aa)

IMEYAGKKDLFHHLRA----NKCFTEQTTKLIVAEIVLAIEYLHAENIIYRDLKPENILIDEKGHIKLTDFG
.|||. . || ..||.    .. .| ..   . ..|  . |||.. |.| |||   |.|..|....| .|||
VMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase DDB0185224.AA Pkinase_Tyr 334-396 24 0.034638 8.03 Pfam 1-68 (270) Show / Hide 
Range on Protein: 334-396
Range on HMM: 1-68/270
Sequence Identity: 24% (17 aa)

FNFYGSLGSGSFGTAKLCRHR----GSGLFFCSKTLRRETIVHEKH--KEHVNNEINIMLNI-SHPYIVK
  |   ||.|.||. .... .    . ..    |.| .|   ....  .|   .|..|| .. .|| ||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVR
Kinase DDB0185224.AA Pkinase_Tyr 516-534 33 3.723311 1.15 Pfam 198-218 (270) Show / Hide 
Range on Protein: 516-534
Range on HMM: 198-218/270
Sequence Identity: 33% (7 aa)

WALGVVVYELVT-GKLP-FSN
|. ||. .|..| |. | . .
WSFGVLMWEIFTYGEQPTYPG