Gene DDB0216387 (Slime mold)

DDB0216387

Species: Slime mold
Alias: DdisK009, DDB0216387
External Links: DictyBase Link ,
Annotation:

Classification

Group: AGC
Family: NDR
Subfamily: NDR-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
DDB0216387.AA Protein None 419 None Fasta, JSON
DDB0216387.kin_dom Protein Kinase Domain None 348 None Fasta, JSON

Protein domain

Protein domains of DDB0216387.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0216387.AA NDR 40-387 33 3.1e-183 570.66 In-house 1-350 (350) Show / Hide 
Range on Protein: 40-387
Range on HMM: 1-350/350
Sequence Identity: 33% (123 aa)

YDIISTIGSGSYGEVCIVREKSTKQVYAMKKIYYTEVSDTELVKKRALRERDAMVICNNKNNKRAPKLYCSFIDDNEGVFYYVMEFIAGGDFNSYCYKRL
..||..||.|..|||..||.|.|...||||.....|..... |..  ..||| |....|| |.. .|||.||.|...  .|.|||...|||...||| .|
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAH-VRAERDIMAEADNK-NPWVVKLYYSFQDKQY--LYLVMEYHPGGDMMTYCY-LL

VDGKKFTEEEIKFYIAELVLCLEAFHSYGLLHRDVKPENLMINKDGHLVLGDFGSSKLANNSGGGGGNFGNTLTVPMSTSYSTSPSSSISSSLLGGSGGF
.. . |||....|||||.|...|..|..|  |||.||.|..|.||||..|.|||   |............|....|| |.||| ......|.. ......
MKMDIFTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFG---LCTGGMIRRHWKQNKQKKPM-TTYST-FHWTHNSWYYQNMKEH

TPSHWNGMAGSAGSSFGSSSLG-----RSFDNTPPNFNSFLRNPHSSYTSYIGTPQYMAVEVVQG-VNYSKLCDFWSLGAILFELVTGQALFVESPDTTE
.|....... |...........     ........|..|...|... ..|..|||.|||.||.|.  .|...||.||||.|..|...|.. |.   ..| 
RPQDFMDNWNSNPMNQKCKCHTQMKDQMKCNVKVLNNRSWKQNRRCLAYSTVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFC---SDTP

QKIRENIGNWRGLL---NTAVQKNQPMSKQAESLIRECIAPERKRPDAS------TIKKHPFF
|.....| ||.  .   .|........|..|. |||....|.......|      .||.||||
QETCMKIMNWKQTWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVDEIKSHPFF
Kinase DDB0216387.AA AGC 40-387 23 2.8e-120 312.27 In-house 1-395 (395) Show / Hide 
Range on Protein: 40-387
Range on HMM: 1-395/395
Sequence Identity: 23% (101 aa)

YDIISTIGSGSYGEVCIVREK------STKQVYAMKKIYYTE-VSDTEL-VKKRALRE------------RDAMVICNNKN-------NKRAPK-LYCSF
.... .|| ||.|.|. ||.|      .|...||||..   . . ...    .....|            |. .. ||...       .    | |..||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

IDDNEGVFYYVMEFIA--------GGDFNSYCYKRLV-DGKKFTEEEIKFYIAE-------LVLCLEAFHS-YGLLHRD-VKPENLMINKDGHLVLGDFG
 |..    | |||..         ||.. .. ... . . ..|.||...||.||       .||.||  ||  |  ||| .||||.....|||. | |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

SSKLANNSGGGGGNFGNTLTVPMSTSYSTSPSSSISSSLLGGSGGFTPSHWNGMAGSAGSSFGSSSLGRSFDNTPPNFNSFLRNP-----------HSSY
..|  .|.|. |.. .. .   |.... ...     .|      ...    . .                   .  |.|...||            .   
LCKEGMNDGEKGQQ-SQSN---MKFHW-HNKKY-Q-KS------NMD----T-N-------------------K-CNPNNWQRNNMSQEDDTTRKKRDRT

TSYIG--TPQYMAVEVVQGVNYSKLCDFWS--LGAILFELVTGQALFVESPDT-------TEQKIRENIG------NWRGLLNT----AVQKNQPMSKQA
..  |  ||.||| |..    |.| || ||  ||....|..||.  |   ..        .. .. ..|       ||.  ..      ..... .|..|
WTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEA

ESLIRECIA-PERKRPD----------ASTIKKHPFF
 .||. ..    .||.           |. ||.||.|
KDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase DDB0216387.AA S_TKc 40-387 24 2.8e-76 260.64 SMART 1-231 (231) Show / Hide 
Range on Protein: 40-387
Range on HMM: 1-231/231
Sequence Identity: 24% (87 aa)

YDIISTIGSGSYGEVCIVREKSTKQVYAMKKIYYTEVSDTELVKKRALRERDAMVICNNKNNKRAPKLYCSFIDDNEGVFYYVMEFIAG--GDFNSYCYK
|.|. .||.|..|.|. .|.|.|....|.|.|            ....||.. .      . .   ||| .| |   . .| |||.. |  ||  .|  |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK----HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKK

RLVDGKK--FTEEEIKFYIAELVLCLEAFHSYGLLHRDVKPENLMINKDGHLVLGDFGSSKLANNSGGGGGNFGNTLTVPMSTSYSTSPSSSISSSLLGG
|   |..  |.| ...||...... ||  || | .|||.||||.....  |. ..|||....                                      
RGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------------------------------

SGGFTPSHWNGMAGSAGSSFGSSSLGRSFDNTPPNFNSFLRNPHSSYTSYIGTPQYMAVEVVQGVNYSK-LCDFWSLGAILFELVTGQALFVESPDTTEQ
                                               |...||| ||| ||.    |.|  || ||.| ||.|...|. .|      ..|
-----------------------------------------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQ

KIRENIGNWRGLLNTAVQKNQPMSKQAESLIRECIAPE-RKRPDASTIKK-------HPFF
.. ..||                |..| ..|| |   . .||| |  . .       ||.|
MMFKKIG----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DDB0216387.AA Ciliate-E2-Unclassified 40-387 21 1.1e-58 201.32 In-house 1-352 (352) Show / Hide 
Range on Protein: 40-387
Range on HMM: 1-352/352
Sequence Identity: 21% (89 aa)

YDIISTIGSGSYGEVCIVREKSTKQVYAMKKIYYTEVSDTELVKK--RALRERDAMVICNNKNNKR---------------APKLYCSFIDDNEGVFYYV
| || .||.|..|.|. ...|..||.|||| .    . .  ....  . ..| ..| . .. .. |                 .... ... ..  .| |
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEFIAGGDFNSYCY-------------KRLVDGKKFTEEEIK-----FYIAELVLCLEAFHSYG-LLHRDVKPENLMINKDG---HLVLGDFGSSKLANN
||.. |||   |.              ...  .|.|||...|     ||.|.....||  |. .  .||| ||||......|   .. . |||.||  ..
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

SGGGGGNFGNTLTVPMSTSYSTSPSSSISSSLLGGSGGFTPSHWNGMAGSAGSSFGSSSLGRSFDNTPPNFNSFLRNPHSSYTSYIGTPQYM----AVEV
. .   ...                                                              . . ....  ... .|||.||    | ||
NNNCD-TNQ------------------------------------------------------------Q-QKMQIWKQQMMWTFCGTPNYMPQYTAPEV

VQGVNYS----KLCDFWSLGAILFELVTGQALFV-ESPDTTEQKIRENIGN---WRGLLNTAVQKNQP------------MSKQAESLIR----ECIAPE
 || ||.    . ||.|||| ||.|...|.  |  .. .  .| | ..| |      |..   |||.              |..|. .|.     ..   
LQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWI-NNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKN

RK-RPDASTIKKHPFF
 . |.... |..||.|
PNKRITFEQILNHPWF
Kinase DDB0216387.AA Ciliate-E2 40-387 18 2.9e-55 188.17 In-house 1-365 (365) Show / Hide 
Range on Protein: 40-387
Range on HMM: 1-365/365
Sequence Identity: 18% (85 aa)

YDIISTIGSGSYGEVCIVREKSTKQVYAMKKIYYTEVSDT-------------ELVKKRALRERDAMVICN-----------------NKNNKRAPKLYC
|..|  ||.|..| |. .. ..... .|.|.|. . ....             . .||. ...   .   .                 . |..   |.| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

SFIDDNEGVFYYVMEFIAGGDFNSYCYKR---------LVDGKKFTEEEIK---------------FYIAELVLCLEAFHSYG-LLHRDVKPENLMINKD
.|.. ..  .|.|||.. |||  .|....           | |.|||.|||               ||||...|.||  || .  .||| ||||...   
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEK-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---

GHLVLGDFGSSKLANNS--------------------------GGGGGNFGNTLTVPMSTSYSTSPSSSISSSLLGGSGGFTPSHWNGMAGSAGSSFGSS
  . . ||| || ....                          .     .                                                  
--IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMD-----Q--------------------------------------------------

SLGRSFDNTPPNFNSFLRNPHSSYTSYIGTPQYMAVEVVQGVN---------YSKLCDFWSLGAILFELVTGQALFVESPDTTEQKIRE---------NI
                 .     . ...||| ||| |...| .         |.. ||.|||| ||.|...|.  |       .|.| .         ..
-----------------IIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-------QQQIKQCKIDFPCPEWQ

GNWRGLLNTAVQK---NQPMSKQAESLIRE----CIAPE-RKRPD-ASTIKKHPFF
 .    ..   .|   ..  |...  ||.     ..  .  ||.. .. |..||.|
KD-TQ-CI-Q-CKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase DDB0216387.AA CAMK 45-387 14 1.6e-50 160.61 In-house 1-425 (425) Show / Hide 
Range on Protein: 45-387
Range on HMM: 1-425/425
Sequence Identity: 14% (75 aa)

TIGSGSYGEVCIVREKSTK------------QVYAMKKIYYTEVSD------------------------TELVKKRALRERDAMVICNNKN----NKRA
|.|.||.|.|  ...|.|.            | .|.| |  . ..|                        ..  .|. .|| . |  .....     .  
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

PKLYCSFIDDN-----------------EGVFYYVM---EFIAGGDFNSYCYKRLVDG---------------KKFTEEEIKFYIAELVLCLEAFHSYGL
 |||  . |..                 .  .| ||   |.. ||.   ... ..|.                ..|||.| ..|.  ..  ..  || . 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

LHRDVKPENLMINKD-----------------GHLVLGDFGSSKLANN------------------SGGGGGNFGNTLTVPMSTSYSTSPSSSISSSLLG
 ||| ||||......                 . . . ||| ..  .                                                     
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQW---------------------------------

GSGGFTPSHWNGMAGSAGSSFGSSSLGRSFDNTPPNFNSFLRNPHSS------YTSYIGTPQYMA-VEVVQGVN--------------YSKLCDFWSLGA
                                             ..      .. . ||| |||  ||..|                |.. || ||.| 
---------------------------------------------TTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGV

ILFELVTGQALFVESPDT----------TEQKIRENIGNWR-GLLNTAVQ------------------KNQPMSKQAESLIRECIAP-ERKRPDASTIKK
||. ...|   | .. |           ..... |.| . .       .                   ..   |... .||| .  .   ||. .. ...
ILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH-FVSQECKDLIRKMLQVDPEKRMTIEQCLN

HPFF
||..
HPWM
Kinase DDB0216387.AA RSK 43-387 23 4.4e-50 172.72 In-house 1-278 (278) Show / Hide 
Range on Protein: 43-387
Range on HMM: 1-278/278
Sequence Identity: 23% (86 aa)

ISTIGSGSYGEVCIVREK---STKQVYAMKKIYYTEVSDTELVKKRALRERDAMVICN-NKNNKRAPKLYCSFIDDNEGVFYYVMEFIAGGDFNSYCYKR
..  | |.||.| ..|..    |.|.|||| .   ..  ..   .....||. .  |.  ..     .|. .| .  || .| .||.. ||..    ...
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPF---IVTLHYAFQT--EGKLYLIMEYCRGGEL----FTH

LVDGKK---FTEEEIKFYIAELVLCLEAFHSYGLLHRDVKPENLMINK---DGHLVLGDFGSSKLANNSGGGGGNFGNTLTVPMSTSYSTSPSSSISSSL
|   |    |.|.| .||.||.|| .|  |. |  ||| |||| . .    .||..| ||| .|..                                  
LQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF----------------------------------

LGGSGGFTPSHWNGMAGSAGSSFGSSSLGRSFDNTPPNFNSFLRNPHSSYTSYIGTPQYMAVEVVQ----GVNYSKLCDFWSLGAILFELVTGQALFVES
        . . |... .                                  ...| .||| |..     .. ..| || ||||....|. ||.  |   
--------RCDHNQWTMT----------------------------------FCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQG-

PDT-TEQKIRENIGNWRGLLNTAVQKNQPMSKQAESLIRECIA-PERKRPD-----ASTIKKHPFF
|.  . ..| ..|.. .  ..     .| .|. | .||| .    . ||.      |. ||.||.|
PNDNNRKEIMKRIQKGK--FSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase DDB0216387.AA STE 40-387 17 7.7e-39 134.79 In-house 1-359 (359) Show / Hide 
Range on Protein: 40-387
Range on HMM: 1-359/359
Sequence Identity: 17% (77 aa)

YDIISTIGSGSYGEVCIVREK------STKQV---------YAMKKIYYTE--VSDTE------------LVKKRALRERDAMVICNNKNNKRAPKLYCS
...|. ||.|..|.|.  . .      .|..|         .|.|.. . .   .| |              ... |.| . |  ||.   .   | |..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHM-HPNIVKYYGC

FIDD-----NEGVFYYVMEFIAGGDFNSYCYKRLVDGKKFT----------EEEIKFYIAELVLC-LEAFHSYGLLHRDVKPENLMINKDGHLVLGDFGS
....     |..  . .||...|| . .   ..   || ..          |..|.... ...   |.  || .  |||.|| | ..       | ||| 
YFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGV

SKLANNSGGGGGNFGNTLTVPMSTSYSTSPSSSISSSLLGGSGGFTPSHWNGMAGSAGSSFGSSSLGRSFDNTPPNFNSFLRNPHS-SYTSYIGTPQYMA
..  ..|. .. . .                 .. .                                       . ..   .  .   .. .||| .||
CGQLTDSMANI-Q-S-----------------NN-I-I-------------------------------------D-CI---ETMQQKRNTFVGTP-WMA

VEVVQG------VNYSKLCDFWSLGAILFELVTGQALFVE-SPDTTEQKIRENI-------------GNWRGLLNTAVQK------------NQPMSKQA
 ||.|.        |.  || ||||  . |..||.  . . .|      |  |.             |.   | ..  |.               .|.  
PEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEF

ESLIRECIAPERK-RPDASTIKK--HPFF
   |. |   . . ||.||   |  |||.
KDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase DDB0216387.AA AktR 120-322 22 2.2e-34 120.56 In-house 77-202 (268) Show / Hide 
Range on Protein: 120-322
Range on HMM: 77-202/268
Sequence Identity: 22% (48 aa)

YYVMEFIAGGDFNSYCYKRLVDGKKFTEEEIKFYIAELVLCLEAFHSY-GLLHRDVKPENLMINKDGHLVLGDFGSSKLANNSGGGGGNFGNTLTVPMST
...||...||.     .  |   |||.||...||.|. .|.|| .|.      || ||||... .|||. ..||| ||                      
FFIMEYCPGGEL----FQHLKKKKKFSEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK----------------------

SYSTSPSSSISSSLLGGSGGFTPSHWNGMAGSAGSSFGSSSLGRSFDNTPPNFNSFLRNPHSSY----TSYIGTPQYMAVEVVQG-VNYSKLCDFWSLGA
                                                           .  .|    .|  |||.||| |...  . . | .|.|..|.
---------------------------------------------------------LQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGI

ILFELVTGQ
 ..|.|||.
FIYEMVTGC
Kinase DDB0216387.AA Pkinase 40-202 33 4.3e-32 114.54 Pfam 1-167 (293) Show / Hide 
Range on Protein: 40-202
Range on HMM: 1-167/293
Sequence Identity: 33% (59 aa)

YDIISTIGSGSYGEVCIVREKSTKQVYAMKKIYYTEVSDTELVKKRALRERDAMVICNNKNNKRAPKLYCSFIDDNEGVFYYVMEFIAGG----DFNSYC
| |...|||||.|.|.. ..|.| ...|.|.| . . .. ... .| |.|   |  .| .|     .||..| |  ..  | |||.  ||    |     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPN---IVRLYDWFED--KDHIYMVMEYCEGGLYVMDLF---

YKRLV--DGKKF--TEEEIKFYIAELVLCLEAFHSYGLLHRDVKPENLMINKDGHL----VLGDFGSSK---LANNSG
  ..   ....|  .|.|.|||. ...  ||  || | .|||.||||..|...||.     ..|||..|   . ||| 
-DYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-
Kinase DDB0216387.AA MAST 106-196 44 2.3e-24 70.79 In-house 63-150 (337) Show / Hide 
Range on Protein: 106-196
Range on HMM: 63-150/337
Sequence Identity: 44% (41 aa)

KLYCSFIDDNEGVFYYVMEFIAGGDFNSYCYKRLVDGK-KFTEEEIKFYIAELVLCLEAFHSYGLLHRDVKPENLMINKDGHLVLGDFGSSK
|...||    .   . |||.  |||..|     | .    . |.. |.||||.|||||  ||||  |||.||.|. | ..||. | ||| ||
KMFYSFQTPCKKYLCMVMEYMEGGDCASL----LRMYGNCMPEWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSK
Kinase DDB0216387.AA MAST 106-196 45 2.8e-21 65.05 In-house 63-147 (334) Show / Hide 
Range on Protein: 106-196
Range on HMM: 63-147/334
Sequence Identity: 45% (41 aa)

KLYCSFIDDNEGVFYYVMEFIAGGDFNSYCYKRLVDGKKFTEEEIKFYIAELVLCLEAFHSYGLLHRDVKPENLMINKDGHLVLGDFGSSK
|...||    .   . |||.  |||..|     | .   | |.  |.||||.|||||  ||.|  |||.||.|. | ..||  | ||| ||
KMFYSFQT--KNYLCMVMEYMEGGDCASL----LHMYGYFDEWMAKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSK
Kinase DDB0216387.AA Pkinase 255-387 23 9.8e-17 60.26 Pfam 156-293 (293) Show / Hide 
Range on Protein: 255-387
Range on HMM: 156-293/293
Sequence Identity: 23% (36 aa)

FGSSSLGRSFDNTPPNFNSFLRNPHSSYTSYIGTPQYMAVEVVQ-GVNYSKLCDFWSLGAILFELVTGQALFVES--PDTTEQKIRENIGNWRGLLNTAV
||.. . .               . | .|.. ||| ||| ||.. |  |.. .| ||.| ||.|...|. .| ..  .|.   ..     . .. |    
FGLAKQFD-------------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDW

QKNQPMS-----------------KQAESLIRECIAP-ERKRPDASTIKKHPFF
..  ..|                 . . ..|. |...   ||| |  |..||.|
PWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase DDB0216387.AA MAST 40-71 40 1.3e-13 37.26 In-house 1-32 (337) Show / Hide 
Range on Protein: 40-71
Range on HMM: 1-32/337
Sequence Identity: 40% (13 aa)

YDIISTIGSGSYGEVCIVREKSTKQVYAMKKI
...|  |. | || |. |. |.|.. .|||.|
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVI
Kinase DDB0216387.AA MAST 40-71 40 1e-11 33.7 In-house 1-32 (334) Show / Hide 
Range on Protein: 40-71
Range on HMM: 1-32/334
Sequence Identity: 40% (13 aa)

YDIISTIGSGSYGEVCIVREKSTKQVYAMKKI
...|  |. | || |. |. |.|.. .|||.|
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVI
Kinase DDB0216387.AA MAST 286-387 33 1.6e-11 33.1 In-house 225-334 (334) Show / Hide 
Range on Protein: 286-387
Range on HMM: 225-334/334
Sequence Identity: 33% (38 aa)

IGTPQYMAVEVVQGVN-YSKLCDFWSLGAILFELVTGQALFVESPDTTEQKIRENIGNWR---GLLNTAVQKN--QPMSKQAESLIRECIAP-ERKRPDA
.|||.|.| ||  |   ..|  | ||.| |..|. .|   |...   | ..| .|| | .     ..     |    ||. |  ||.   .|  |||. |
CGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDD---TPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGA

S----TIKKHPFF
.     .|.||||
NNGADEVKQHPFF
Kinase DDB0216387.AA MAST 286-321 45 1.9e-09 24.38 In-house 229-265 (337) Show / Hide 
Range on Protein: 286-321
Range on HMM: 229-265/337
Sequence Identity: 45% (17 aa)

IGTPQYMAVEVVQGVN-YSKLCDFWSLGAILFELVTG
.|||.|.| ||  |   |.|  | ||.| |..|. .|
CGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVG
Kinase DDB0216387.AA AktR 40-98 26 1.7e-08 29.22 In-house 1-60 (268) Show / Hide 
Range on Protein: 40-98
Range on HMM: 1-60/268
Sequence Identity: 26% (16 aa)

YDIISTIGSGSYGEVCIVREK-STKQVYAMKKIYYTEVSDTELVKKRALRERDAMV-ICNN
....  .|.| .|.|  |..|  ....|||| |  ..  . .. ......||. |  .||.
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQ-MHHTITERNIMEMCCNH
Kinase DDB0216387.AA TyrKc 40-387 12 2.4e-05 -136.32 SMART 1-280 (280) Show / Hide 
Range on Protein: 40-387
Range on HMM: 1-280/280
Sequence Identity: 12% (50 aa)

YDIISTIGSGSYGEVCIVREKSTKQVYAMKKIY-YTEVSDTELVKKRALRERDAMVICNN-KNNKRAPKLYCSFIDDNE-----GVFYYVMEFIAGGDFN
   . ..|.| .|||.  . |   .  | |..  ..        ..  .||  | . |.  ....   .||   ... .     .  . |||. ..|| .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--------REDFMRE--ARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK

SYC-YKRLVDGKKFTEEEIKFYIAELVLCLEAFHSYGLLHRDVKPENLMINKDGHLVLGDFGSSKLANNSGGGGGNFGNTLTVPMSTSYSTSPSSSISSS
.|  ..|      .. ..   .        |  || .. |||    | ......                                              
DYLRKHRPK----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----------------------------------------------

LLGGSGGFTPSHWNGMAGSAGSSFGSSSLGRSFDNTPPNFNSFLRN----------PHSSY------TSYI------GTPQ-----YMAVEVVQGVNYSK
                                                         . ..      ..|.      |.        || |. .   .. 
---------------------------------------------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

LCDFWSLGAILFELVT-GQALFVE------SPDTTEQKIRENIGNWRGLLNTAVQKNQP-----MSKQAESLIRECIAP-ERKRPDASTIKKHPFF
  | || |  ..|. | ||    .      |..   .....     .   .       |     ...   .....| .    .||  |.|  | .|
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY------PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase DDB0216387.AA AktR 375-387 38 0.006229 7.64 In-house 256-268 (268) Show / Hide 
Range on Protein: 375-387
Range on HMM: 256-268/268
Sequence Identity: 38% (5 aa)

RPDASTIKKHPFF
..... ||.||.|
CNGWEEIKSHPWF
Kinase DDB0216387.AA MAST 381-387 85 0.021345 2.4 In-house 331-337 (337) Show / Hide 
Range on Protein: 381-387
Range on HMM: 331-337/337
Sequence Identity: 85% (6 aa)

IKKHPFF
||.||||
IKQHPFF