Gene PKA (Slime mold)
PKA
Sequence
Protein domains of PKA.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | PKA.AA | PKA | 336-590 | 65 | 2.2e-202 | 678.62 | In-house | 1-263 (263) | Show / Hide |
Range on Protein: 336-590 Range on HMM: 1-263/263 Sequence Identity: 65% (172 aa) FKQIRVIGTGTFGKVYLIQNTKDGCYYAMKCLNKAYVVQLKQVEHLNSEKSILSSIHHPFIVN-LYQAFQDEKKLYLLFEYVAGGEVFTHLRKSMKFSNS |..|...|||.||.|.|... ..|.|||||.|.|...|.|||||| ..||.||..|.|||||. .|. |||...||...|||.|||.|..||||..|||. FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP TAKFYAA-EIVLALEFLHKQNIVYRDLKPENLLIDNQGHIKITDFGFAKRVEDRTFTLCGTPEYLAPEIIQSK-GHGKAVDWWALGILIFEMLAGYPPFY .|||||| .||||||.||.|||.||||||||.|||..||||||||||||.|.|||.||||||||||||||||| ||||.||||||||||.|||||||||| HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDDRTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFY DD--DTFAIYNKILAGRITFPLGFDVDA---KDLIKRLLTADRTRRLGALKDGALDVKNHRWF |. |...||.||..|.| || ||.|| |||||.||..|.|.|.| .|.|. |.|||.|| DHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF |
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| Kinase | PKA.AA | AGC | 336-590 | 35 | 1.5e-189 | 495.5 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 336-590 Range on HMM: 1-395/395 Sequence Identity: 35% (140 aa) FKQIRVIGTGTFGKVYLIQNTK-----D-GCYYAMKCLNKAY-VVQLK--QVEHLNSE------------KSILSSIH----------HPFIVN-LYQAF |. ..|||.|.|||||| . . | | |||||.|.|.. .|..| .||| ..| . ||. .. |||||. |. .| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF QDEKK--LYLLFEYVA---------GG-EVFTHLR---KSMKFSNSTAKFYAAE-------IVLALEFLHK-QNIVYRD-LKPENLLIDNQGHIKITDFG ||... ||.. ||. || | |.||. |. .|. ..|.||||| ||||||.||. ..|..|| |||||.|.|..||||.|||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG FAKRVE-----------------------------------------------------DRTFTLCG--TPEYLAPEIIQSKGHGKAVDWWA--LGILIF ..|.. ||| |.|| ||||.||||. .|||.|||. ||.|.. LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY EMLAGYPPFYDD----------DTFAIYNKILAG------RITFP----------LGFDVDAKDLIKRLLTADRTRRLGALKD-----GALDVKNHRWF |||.||||||.| . . ...||. | ...|| |...||||||.||. |...|||.... || ..||| || EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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| Kinase | PKA.AA | SGK | 336-590 | 43 | 1.3e-140 | 437.23 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 336-590 Range on HMM: 1-283/283 Sequence Identity: 43% (124 aa) FKQIRVIGTGTFGKVYLIQNTKD------------------GCYYAMKCLNKAYVV-------QLKQVEHLNSEK-SILSSIHHPFIVNLYQAFQDEKKL |. . ||| | |||||. . .| . |||| |.|. .. . |.. | .|. ||. . ||||||| ||| ..|| FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL YLLFEYVAGGEVFTHLRKSMKFSNSTAKFYAAEIVLALEFLHKQNIVYRDLKPENLLIDNQGHIKITDFGFAK---RVEDRTFTLCGTPEYLAPEIIQSK |. .|| ||| | ||.. .|. . |.|||||||.||| ||.|.|.||||||||.| | |||...|||| .| .| ||| ||||||||||... . YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ GHGKAVDWWALGILIFEMLAGYPPFYDDDTFAIYNKILAGRITFPLGFDVDAKDLIKRLLTADRTRRLGALKDGALDVKNHRWF .|...|||| ||.. .||. | ||||. .. | .|. . . .| .. .||.|||. ||. |.. |||. |......||| .| PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGT-KRDFMEIKNHPFF |
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| Kinase | PKA.AA | Akt | 336-590 | 48 | 2.7e-135 | 434.96 | In-house | 1-264 (264) | Show / Hide |
Range on Protein: 336-590 Range on HMM: 1-264/264 Sequence Identity: 48% (127 aa) FKQIRVIGTGTFGKVYLIQNTKDGCYY-AMKCLNKAYVVQLKQVEHLNSEKSILSSIHHPFIVNLYQAFQDEKKLYLLFEYVAGGEVFTHLRKSMKFSNS | ..|.| |.||||.| . ... .| ||| | | | .| .|||| |. || . |||||||. .||...|||. .|. ||| |.||.. .|| . FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED TAKFYAAEIVLALEFLHKQNIVYRD-LKPENLLIDNQGHIKITDFGFAK-R-VED--RTFTLCGTPEYLAPEIIQSKGHGKAVDWWA-LGILIFEMLAGY .|.||.|||.||.|.||..||.||| |||||.|.|..|||..|||| .| . | .| |.|||||||||||.. .||.||||||. ||....||. | RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR PPFYDDDTFAIYNKILAGRITFP--LGFDVDAKDLIKRLLTADRTRRLGALKDGALDVKNHRWF ||||..| . ||. . . || .. ..||||..||. |...|||. ...| ..|.| || PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF |
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| Kinase | PKA.AA | AktR | 336-590 | 44 | 4.4e-124 | 418.53 | In-house | 1-268 (268) | Show / Hide |
Range on Protein: 336-590 Range on HMM: 1-268/268 Sequence Identity: 44% (120 aa) FKQIRVIGTGTFGKVYLIQNT-KDGCYYAMKCLNKAYVVQLKQVEHLNSEKSILS-SIHHPFIVNLYQAFQDEKKLYLLFEYVAGGEVFTHLRKSMKFSN |. ....| |.|||||| | ... .|||| . | ....| .|. |. |. . |||||.|...||...||... ||..||| |.||.|. |||. FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE STAKFYAAEIVLALEFLHKQ-NIVYRDLKPENLLIDNQGHIKITDFGFAK----R-VEDRTFTLCGTPEYLAPEIIQS-KGHGKAVDWWALGILIFEMLA ..|.||.|.|.||||.||.. ||.||||||||.|.| ||.|||||| .| . .... ..||||||.|||.|. |||.|.|||||.||.|.||.. EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT GYPPFYDDDTFAIYNKILAGR---ITFPLGFDVDAKDLIK-RLLTADRTRRLGALKDGALDVKNHRWF |.||||.... .. ||. . ...| | .||||. .|| . . ||| . |. ..|.| || GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF |
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| Kinase | PKA.AA | RSK | 339-590 | 45 | 1.2e-115 | 390.45 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 339-590 Range on HMM: 1-278/278 Sequence Identity: 45% (127 aa) IRVIGTGTFGKVYLIQNT---KDGCYYAMKCLNKAYVVQLKQ-VEHLNSEKSILSSIH-HPFIVNLYQAFQDEKKLYLLFEYVAGGEVFTHLRKSMK--- ..| |.| .|||.| . . . | .|||| |.|| .|| . ..| | .||. . |||||.|. |||.|.|||| ||. ||| ||||.| LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC FSNSTAKFYAAEIVLALEFLHKQNIVYRDLKPENLLIDN---QGHIKITDFGFAKR-VED---RTFTLCGTPEYLAPEIIQ----SKGHGKAVDWWALGI || ..|.||.||||||.|.||.| |..||||||| | |. .||||.|||||.| . | .| | |.| ||.|||.. .||.||.||| ||. FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV LIFEMLAGYPPFYD---DDTFAIYNKILAGR--ITFP--LGFDVDAKDLIKRLLTADRTRRLGALKDGALDVKNHRWF |..|||.|.|||. .. | ..|. |. |.| .|||||...|. | .|||. ...| ..|.| || LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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| Kinase | PKA.AA | S_TKc | 336-590 | 38 | 3.9e-114 | 386.38 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 336-590 Range on HMM: 1-231/231 Sequence Identity: 38% (102 aa) FKQIRVIGTGTFGKVYLIQNTKDGCYYAMKCLNKAYVVQLKQVEHLNSEKSILSSIHHPFIVNLYQAFQDEKKLYLLFEYVAG--GEVFTHLRKSMK--- .. .|.|| |.|||||. ...|.| ..|.|... ||. .| .||.. |||.||.|| .||| ..||. .||. | |..|....| . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---FSNSTAKFYAAEIVLALEFLHKQNIVYRDLKPENLLIDNQGHIKITDFGFAKRVEDRTFTLCGTPEYLAPEIIQSKGHGK-AVDWWALGILIFEMLA |. .|.||...|..|||..|...|..|||||||.|.|. ||||.|||.|... |.||||.|.|||.. |.|| ..|||..|....|||. RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC GYPPFYDDDTFAIYNKILAGRITFPLGFDVDAKDLIKRLLTADRTRRLGALKDGA--LDVKNHRWF |||||. . .....||. . .|||.|...|. | ..|..| . . .|.|.| || GYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | PKA.AA | p70 | 336-590 | 38 | 3.9e-105 | 355.57 | In-house | 1-299 (299) | Show / Hide |
Range on Protein: 336-590 Range on HMM: 1-299/299 Sequence Identity: 38% (115 aa) FKQIRVIGTGTFGKVYLIQNTK---DGCYYAMKCLNKAYVVQ-LKQVEHLN-------------------------SEKSILSSIHHPFIVNLYQAFQDE |. ..|.| | .|||... .. | .|||| | || .| | .| | .||... ||||. | |||.. FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN KKLYLLFEYVAGGEVFTHLRKSMKFSNSTAKFYAAEIVLALEFLHKQNIVYRDLKPENLLIDNQGHIKITDFGFAK-RVEDRTF------------TLCG ||||. || ||| |.|| . . ||.||..||..|||.||.. |.|||||||| . . |||.. |||| | ..| . |.|| GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG TPEYLAPEIIQSKGHGKAVDWWALGILIFEMLAGYPPFYDDDTFAIYNKILAGR--ITFPLGFDVDAKDLIKRLLTADRTRRLGALKDGALDVKNHRWF |.|| ||||. .||..|||||.||.|.. || | ||| . . .||| |. .. | ...||||.|| . | |.|| . | |.. | .| TIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF |
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| Kinase | PKA.AA | PKG | 336-590 | 46 | 4e-104 | 352.24 | In-house | 1-260 (260) | Show / Hide |
Range on Protein: 336-590 Range on HMM: 1-260/260 Sequence Identity: 46% (121 aa) FKQIRVIGTGTFGKVYLIQNTKDG-CYYAMKCLNKAYVVQLKQVEHLNSEKSILSSIHHPFIVNLYQAFQDEKKLYLLFEYVAGGEVFTHLRKSMKFSNS .| | | | || | |.| .. .|.||..|. .| .| || ||| |. . . .||| || | |.|..|.| | |||. | ||. .| .. LKIIATLGVGGFGRVELVQYNHQKSRTFALKCMKKRHIVDTRQQEHIMSEKNIMMECRCDFIVRLYRTFRDQKYVYMLMEACMGGELWTILRDRGHFDDK TAKFYAAEIVLALEFLHKQNIVYRDLKPENLLIDNQGHIKITDFGFAKRVE--DRTFTLCGTPEYLAPEIIQSKGHGKAVDWWALGILIFEMLAGYPPFY |..||.| .| |...||..||.|||||||||. ||.| .|. ||||||... .| | |||||| ||||| ||| .||.||||||..| | | ||| TTRFYCACVVEAFDYLHRKNIIYRDLKPENLMLDNRGYCKLVDFGFAKKIGQGRKTWTFCGTPEYVAPEIILNKGHDRSVDYWALGILMCELLTGNPPFS DDDTFAIYNKILAG--RITFPLGFDVDAKDLIKRLLTADRTRRLGALKDGALDVKNHRWF | .|| || | . || |...||.| | ||| .| | |.| |.|| GSDPMKTYNIILKGIDMWEFPRKITRWAQNMIKKLCRDNPTERLGYQKNGINDIKKHKWF |
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| Kinase | PKA.AA | Pkinase | 336-590 | 32 | 5.2e-96 | 330.07 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 336-590 Range on HMM: 1-293/293 Sequence Identity: 32% (98 aa) FKQIRVIGTGTFGKVYLIQNTKDGCYYAMKCLNKAYVVQLKQVEHLN-SEKSILSSIHHPFIVNLYQAFQDEKKLYLLFEYVAGG----EVFTHLR--KS .. .|.|| |.||.||. .. ..|. .|.|...| |...|.. || .|. ...||.|| || .|.|....|. .||. || . |.... .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH MKF--SNSTAKFYAAEIVLALEFLHKQNIVYRDLKPENLLIDNQGHI----KITDFGFAK---RVEDRTFTLCGTPEYLAPEIIQ-SKGHGKAVDWWALG .| | ..|||. .|. .||..|...|..|||||||.||||.||| ||.|||.|| ... |.||||.|.|||.|. ....|..||.|..| GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCG ILIFEMLAGYPPFYDD------DTFAIYNKILAGRITFPLGFD---------------------VDAKDLIKRLLTADRTRRLGALKDGALDVKNHRWF ....||| |.|||... | .....|. ... |. . ..||.||..|. | ..|.. | ....| || CILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQHPWF |
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| Kinase | PKA.AA | MAST | 336-482 | 41 | 2.8e-67 | 204.37 | In-house | 154-303 (337) | Show / Hide |
Range on Protein: 336-482 Range on HMM: 154-303/337 Sequence Identity: 41% (62 aa) FKQIRVIGTGTFGKVYLIQNTKDGCYYAMKCLNKAYVVQLKQVEHLNSEKSILSSIHHPFIVNLYQAFQD--EKKLYLLFEYVAGGEVFTHLRKSM-KFS |. |..|. | .|.||| .. | . .||| .|. . .||.....|. ||. . ||.|... .|| .|.|.. ||. || ....|| . FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP NSTAKFYAAEIVLALEFLHKQNIVYRDLKPENLLIDNQGHIKITDFGFAK . ||.| ||.||.||.||.. || |||||.|.||| ||||.||||..| EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSK |
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| Kinase | PKA.AA | MAST | 336-482 | 41 | 3.2e-63 | 202.51 | In-house | 155-301 (334) | Show / Hide |
Range on Protein: 336-482 Range on HMM: 155-301/334 Sequence Identity: 41% (61 aa) FKQIRVIGTGTFGKVYLIQNTKDG-CYYAMKCLNKAYVVQLKQVEHLNSEKSILSSIHHPFIVNLYQAFQDEKKLYLLFEYVAGGEVFTHLRKSMKFSNS |. |..|. | .||||| ...|.. .||| ..|.. ..|.....|. ||. . ||.|... .|| ...|.. ||. || ....|. | . FEFIKPISKGAYGKVYL-VKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEW TAKFYAAEIVLALEFLHKQNIVYRDLKPENLLIDNQGHIKITDFGFAK .||.| ||.||.||.||.. || |||||.|.|||. ||||.||||..| MAKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSK |
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| Kinase | PKA.AA | MAST | 492-590 | 40 | 1.3e-48 | 146.28 | In-house | 229-337 (337) | Show / Hide |
Range on Protein: 492-590 Range on HMM: 229-337/337 Sequence Identity: 40% (45 aa) CGTPEYLAPEIIQSKG-HGKAVDWWALGILIFEMLAGYPPFYDDDTFA-IYNKILA--GRITFPLG--------FDVDAKDLIKRLLTADRTRRLGALKD ||||.|.|||.| .| .||.||||..|| ..| |.|.||| .| | ..|. .| .| . . .|.||||.||. . |||| CGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGAN-- GALDVKNHRWF || ..|.|. | GADEIKQHPFF |
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| Kinase | PKA.AA | MAST | 491-590 | 44 | 7.4e-44 | 139.06 | In-house | 224-334 (334) | Show / Hide |
Range on Protein: 491-590 Range on HMM: 224-334/334 Sequence Identity: 44% (50 aa) LCGTPEYLAPEIIQSKG-HGKAVDWWALGILIFEMLAGYPPFYDDDTFAIYNKILAGR---ITFPLG--------FDVDAKDLIKRLLTADRTRRLGALK .||||.|.|||.| .| |||.||||..|| ..| |.|.||| ||.. |...|| . | .| | . ..|.|||..||. | |||| CCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGANN DGALDVKNHRWF || .||.|. | -GADEVKQHPFF |
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| Kinase | PKA.AA | S_TK_X | 591-648 | 22 | 4.5e-17 | 63.96 | SMART | 1-79 (79) | Show / Hide |
Range on Protein: 591-648 Range on HMM: 1-79/79 Sequence Identity: 22% (18 aa) SDINWERLYQ--RRDNGPFIPKIQ----HQGDSSNFE-MYDEEEMVEEPPSSNYVD--------------PYAHLFKDF ..|.|..||. .. ||.|||. ...| |||. ..||. .. |.... .. |.. ....| RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF |
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| Kinase | PKA.AA | TyrKc | 336-590 | 20 | 2.1e-15 | 26.44 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 336-590 Range on HMM: 1-280/280 Sequence Identity: 20% (61 aa) FKQIRVIGTGTFGKVYLIQNTKDGCYYAMKCLNKAYVVQLKQVEHLNSEKSILSSI--HHPFIVNLYQAFQDE-------KKLYLLFEYVAGGEVFTHLR . ....| | ||.||. . . | |.|.. .| . .| .|.... ||| ||.|| . .. . |....||...| .|| ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR KSMK-FSNSTAKFYAAEIVLALEFLHKQNIVYRDLKPENLLIDNQGHIKITDFGFAKRVEDR--------TFTL----CGTP----EYLAPEIIQSKGHG |. . ..... .. | |.||..|.. ||| | |.......||.||| .. ..| . . .| .||| |. . KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT KAVDWWALGILIFEMLA-GYPPFYD-----DDTFAIYNKILAG-RITFPLG--------FDVDAKDLIKRLLTADRTRRLGALKDGALDVKNHRWF . | |. |....|.. | .| .. . . ..... .| | | . ...|. .| | |. | TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-------HECF |
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| Kinase | PKA.AA | Pkinase_Tyr | 336-486 | 25 | 2.8e-14 | 48.99 | Pfam | 1-164 (270) | Show / Hide |
Range on Protein: 336-486 Range on HMM: 1-164/270 Sequence Identity: 25% (43 aa) FKQIRVIGTGTFGKVYLIQNTKDGCYY----------AMKCLNKAYVVQ-LKQVEHLNSEKSILSSI-HHPFIVNLYQAFQ-DEKK--LYLLFEYVAGGE . ....| | ||.||. | .. | |.|. . . . | . .| .|.... ||| ||.|| . ... .|. .||...| ITFGKKLGEGAFGEVYK------GTWKGDPDNTKIPVAVKMLKEGAMHEQN-CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGD VFTHLRK----SMKFSNSTAKFYAAEIVLALEFLHKQNIVYRDLKPENLLIDNQGHIKITDFGFAKRV-ED ..||| ... .. ....| ..|.|. .|.. ||| | |.......||.||| |. . .| LLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYND |
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