Gene FHAK3 (Slime mold)

FHAK3

Species: Slime mold
Alias: DDB0219952, DdisK041, FHAK3
External Links: DictyBase Link ,
Annotation:

Classification

Group: CAMK
Family: RAD53

Sequence

Name Sequence Type Origin Length Description Download
FHAK3.AA Protein None 749 None Fasta, JSON
FHAK3.kin_dom Protein Kinase Domain None 273 None Fasta, JSON

Protein domain

Protein domains of FHAK3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
FHA FHAK3.AA FHA 47-167 18 2.4e-10 43.14 Pfam 1-73 (73) Show / Hide 
Range on Protein: 47-167
Range on HMM: 1-73/73
Sequence Identity: 18% (24 aa)

IFFGRNPKRCQVVLH-DPT-VSGIHCRI-FREEIPCQKYNNNNNNDGDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTKNYITKITD--TSSN
. .||. ..| .||. ||. ||. ||.| ....                                                          |.|  .|.|
WTIGRD-PDCDIVLDNDPSFVSRHHCEIRRYDNG------------------------------------------------------RWYIRDLGCSTN

GTFV--KGCILGKDKTTIIQNGDMVSFT
||||   |  ...........|| ..| 
GTFVTGNGQRIQPGEPHRLHHGDRIRFG
FHA FHAK3.AA FHA 46-150 14 6e-06 27.03 SMART 1-49 (49) Show / Hide 
Range on Protein: 46-150
Range on HMM: 1-49/49
Sequence Identity: 14% (16 aa)

SIFFGRNPKRCQVVLHDPTVSGIHCRIFREEIPCQKYNNNNNNDGDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTKNYITKITDTS---SNG
 . .||..  |...| .|..|  ||.|. ..                                                          | | .   .||
TWTIGRHS--CDIQLPHPSISRHHCQIR-DGD--------------------------------------------------------YIIDLGEHSTNG

TFVKGCIL
|.| |  .
TYVNGRRV
Kinase FHAK3.AA RAD53 199-472 46 2.5e-208 627.33 In-house 1-305 (305) Show / Hide 
Range on Protein: 199-472
Range on HMM: 1-305/305
Sequence Identity: 46% (142 aa)

YSIQGILGTGNFSVVKRCIRRDTGEVFAVKIIDKKK-F---WSQTKTRRQMESEVEILQKIKHPNIISIIDIVQS-DRYFYIVLELATGGELFEKIK-QK
|.....||.|||..||......|....|.||||||| |   ....|...|...|||||.|..||.||.|.||... ..|.|.||||.||||||.||. .|
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

GR---FSEPEAKDTFKQILEAVSYLHDLNISHRDLKPENILISAVSHGK-------------SSVIKVTDFGLAKIIGEKEMATTLCGTPLYVAPEIIR-
..   |.|...|..|.|...||.||||..|.||||||||||........             |..||.|||||.|..||.....|.||||.|||||.|. 
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVITS

---NCLHGDGGAQVNTGYGKEVDVWSLGCILYILLSGRPPFDFD-----HTNNFNLKLINQGLYNFSLPVWDVVTENAKDLIKKLLNVDPTKRISTKGAL
   ||.|.....||..||.|.||.||.||||||.|.|.|||..|     |..... ...||| |.|. |.||...|.||||||..|.|||.||.....||
KGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEAL

SHDWF
.|.|.
NHPWM
Kinase FHAK3.AA CAMK1 199-472 41 9.3e-137 400.1 In-house 1-276 (276) Show / Hide 
Range on Protein: 199-472
Range on HMM: 1-276/276
Sequence Identity: 41% (121 aa)

YSIQGILGTGNFSVVKRCIRRDT---GEVFAVKIID-KKKFWS---QTKTRRQMESEVEILQK---IKHPNIISIIDIVQSDRYFYIVLELATGGELFEK
| .. ..|.| ||.|..|....|   |. .|.|.|| ||       | | . ..| |.||..|   |.|||||..... .||..||.|.|| ||||||..
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQ-K-QEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDR

IKQKGRFSEPEAKDTFKQILEAVSYLHDLNISHRDLKPENILISAVSHGKSSVIK--VTDFGLAKIIGEKE-MATTLCGTPLYVAPEIIRNCLHGDGGAQ
| .|| ..| .| .. ||||.|| |.|...| ||||||||.| .  .    | ||  . ||||.||....| . .| |||| |||||.. .         
IVEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYY--DKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKK-------

VNTGYGKEVDVWSLGCILYILLSGRPPFDFDHT-NNFNLKLINQGLYNFSLPVWDVVTEN-AKDLIKKLLNVDPTKRISTKGALSHDWF
  ..|.|..|.|| |.|.|||| | ||| .| . .|. ...|  . |.|  | || . .  |||.||..|.|||.||.. . .| | |.
-DKPYDKACDMWSIGVITYILLCGYPPF-YDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase FHAK3.AA CAMK 204-472 27 4.89999999999e-131 424.75 In-house 1-425 (425) Show / Hide 
Range on Protein: 204-472
Range on HMM: 1-425/425
Sequence Identity: 27% (118 aa)

ILGTGNFSVVKRCIRRDTG------------EVFAVKIIDKKK------------------------FWSQTKTRRQMESEVEILQK-------IKHPNI
.||.|.|..||.||.. |.            . .|.|||||||                        .| . |.|.....|.||..|       ..||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

ISIIDIVQS-------------------DRYFYIVL---ELATGGEL----FEKIKQK---------------GRFSEPEAKDTFKQILEAVSYLHDLNI
|..... ..                   |...|.|.   |...||||    |..|...               |||.| ||.  |.||..|| |.|..||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

SHRDLKPENILISAVSHGKS------------SVIKVTDFGLAKIIGEKE------------------------MATTLCGTPLYVA-PEIIRNCLHGDG
 ||||||||||..  . ...              ||..|||.|... ..|                        . .| |||| |.| ||... . |.. 
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

G---AQVNTGYGKEVDVWSLGCILYILLSGRPPFDFDH------------TNNFNLKLINQGLYNFSLPV------------WDVVTEN--------AKD
.   .. ...||...|.||.|.||||.|.|.|||. |.            . .  .. | .| |.|  |             || ....        .||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LIKKLLNVDPTKRISTKGALSHDWF
||.|.|.|||.||.. . .|.| |.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase FHAK3.AA S_TKc 199-472 35 1.8e-111 377.57 SMART 1-231 (231) Show / Hide 
Range on Protein: 199-472
Range on HMM: 1-231/231
Sequence Identity: 35% (102 aa)

YSIQGILGTGNFSVVKRCIRRDTGEVFAVKIIDKKKFWSQTKTRRQMESEVEILQKIKHPNIISIIDIVQSDRYFYIVLELATG--GELFEKIKQKGR--
| |  ..| | |..|..|. ..||...|.|||.           .....|..||.| .||||. ..|. |.  ..|.|.|.. |  |.||. ||..||  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----FSEPEAKDTFKQILEAVSYLHDLNISHRDLKPENILISAVSHGKSSVIKVTDFGLAKIIGEKEMATTLCGTPLYVAPEIIRNCLHGDGGAQVNTGY
    |.| .|.  ..||..|. |.|...| ||||||||||..        .||..|||||...      ||.|||| |.|||..              ||
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL------TTFCGTPWYMAPEVL--------------GY

GK-EVDVWSLGCILYILLSGRPPFDFDHTNNFNLKLINQGLYNFSLPVWDVVTENAKDLIKKLLNVDPTKRISTKGALS-------HDWF
|| ..|.||.|||||..|.|.|||.         ..... .           .. |||.|.|.|..||.||..   ||        | ||
GKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase FHAK3.AA Ciliate-E2a 199-472 39 4.7e-109 322.15 In-house 1-275 (275) Show / Hide 
Range on Protein: 199-472
Range on HMM: 1-275/275
Sequence Identity: 39% (111 aa)

YSIQGILGTGNFSVVKRCIRRDTGEVFAVKIIDKKKFWSQTKTRRQMESEVEILQKIKHPNIISIIDIVQSDRYFYIVLELATGGELFEKIKQKGRFSEP
|... ..|.||| .|.   ...||. ||.|...| |.  |.| ..... |. |.....||||| .... ......|.|.|.  ||||..||||..|| | 
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE

--EAKDTFKQIL-EAVSYLHDLNISHRDLKPENILIS-AVSHG-KSSVIKVTDFGLAKII--GEKEMATTLCGTPLYVAPEIIRNCLHGDGGAQV--NTG
  |..|  .|.| ....|.| .|| ||||||||||.    . .   | ||. |||||. |   ||.   . |||| |||||.. |        .|  .. 
IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNN-------KEVLKHKQ

YGKEVDVWSLGCILYILLSGRPPFDFDHTNNFNLKLINQGLYNFSLPV-WDVVTENAKDLIKKLLNVDPTKRISTKGALSHDWF
|.. .|.||.|.|.||||.|.|||.   .|   |... .  ..|. |. |  .. ..|||.||.|..|| |||. . || | ||
YDTKCDMWSCGVIFYILLCGKPPFKGKTYNEI-LQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase FHAK3.AA Pkinase 199-472 36 2.3e-103 354.48 Pfam 1-293 (293) Show / Hide 
Range on Protein: 199-472
Range on HMM: 1-293/293
Sequence Identity: 36% (114 aa)

YSIQGILGTGNFSVVKRCIRRDTGEVFAVKIIDKKKFWS---QTKTRRQMESEVEILQKIKHPNIISIIDIVQSDRYFYIVLELATGG----ELFEKIK-
| | ...| |.|..|..|....||...|||||.|..  |   ||..|.   ||..|.....||||. ..|....... |.|.|.. ||    .||. |. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL---SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

-QKGRF--SEPEAKDTFKQILEAVSYLHDLNISHRDLKPENILISAVSHGKSSVIKVTDFGLAKI--IGEKEMATTLCGTPLYVAPEIIRNCLHGDGGAQ
 ..|.|  || |.|. ..|||... |.|. .| |||||||||||.   | ..  .|..||||||   .  .. .||.|||| |.|||.||          
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR----------

VNTGYGKEVDVWSLGCILYILLSGRPPFDFDH------TNNFNLKLINQGLYNFSLPVWDVVT-----------------ENAKDLIKKLLNVDPTKRIS
 ...||..||.||.|||||..|.|||||. .|      . .. ...| .. . |. | |. .                  |..||.||..|..||.||..
GGQYYGPKVDMWSCGCILYEMLCGRPPFP-GHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT

TKGALSHDWF
 . .| |.||
AEQILQHPWF
Kinase FHAK3.AA DCAMKL 199-472 38 7.5e-99 308.19 In-house 1-279 (279) Show / Hide 
Range on Protein: 199-472
Range on HMM: 1-279/279
Sequence Identity: 38% (113 aa)

YSIQGILGTGNFSVVKRCIRRDTG-EVFAVKI-----------------IDKKKFWSQTKTRRQMESEVEILQKIKHPNIISIIDIVQSDRYFYIVLELA
|.|  | | |||.||. |..| || . .| ||                 |||.|     .     ..||.|.||||||.||.... .  .   |.|.|..
YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKGKEHM---IDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVMEYV

TGGELFEKIKQKGRFSEPEAKDTFKQILEAVSYLHDLNISHRDLKPENILISAVSHGKSSVIKVTDFGLAKIIGE-KEMATTLCGTPLYVAPEIIRNCLH
.|| ||. | . ..|.|..|     .. .|  |||..|| |||.|||| |.    .| .  .|  |||||... .      | |||| ||||||..    
QGGDLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDG-EKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILM----

GDGGAQVNTGYGKEVDVWSLGCILYILLSGRPPFDFDHTNNFNL-KLINQGLYNFSLPVWDVVTENAKDLIKKLLNVDPTKRISTKGALSHDWF
        |||| .||.|..| |||||| | |||     .   | ..| || ..|  | || ..  |||||...|.||| || . .  ..| | 
-------ETGYGCKVDIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase FHAK3.AA Ciliate-E2 199-472 28 4.6e-94 318.81 In-house 1-365 (365) Show / Hide 
Range on Protein: 199-472
Range on HMM: 1-365/365
Sequence Identity: 28% (110 aa)

YSIQGILGTGNFSVVKRCIRRDTGE-----------------------VFAVKIIDKK--KFWSQ-TKTRRQME------SEVEILQKIKHPNIISIIDI
| .. ..|.|||..|..| .. ...                        .|.||. |.  ....|  .  |...       | .||....||||| ... 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VQ--SDRYFYIVLELATGGELFEKIKQK-----------GRFSEPEAKDTFKQILE---------------AVSYLHDLN-ISHRDLKPENILISAVSHG
 |  .| ..|.|.|.. ||.||. ||..           ..|.| |.|. .||||.               |. |||  | | |||.||||||.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

KSSVIKVTDFGLAKIIGEK--------------------------------EMATTLCGTPLYVAPEIIR------NCLHGDGGAQVNTGYGKEVDVWSL
    ||..||||.|.. ..                                .|. |.|||| |.||||..      .        |  .||....|.|||
----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ--------QKQKGYDYKCDIWSL

GCILYILLSGRPPFDFDHTNNFNLKLINQGLYNFSLP--------------VWDVVTENAKDLIKK----LLNVDPTKRIS-TKGALSHDWF
|.|||..|.|.|||         .. | |. ..|. |               |. .....||||||    .|..|| |||.  . .| | ||
GVILYEMLFGKPPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase FHAK3.AA RSK 199-472 33 1.1e-93 317.51 In-house 1-278 (278) Show / Hide 
Range on Protein: 199-472
Range on HMM: 1-278/278
Sequence Identity: 33% (97 aa)

YSIQGILGTGNFSVVKRCIRRDTGEVFAVKIIDKKKFWSQTKTRRQMESEVEILQKIK-HPNIISIIDIVQSDRYFYIVLELATGGELFEKIKQKGR---
 .  | .| | ......|...||| ..|.|...|.|.    |. |    |..||. .. ||.|..  .  | . ..|...|.  |||||........   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FSEPEAKDTFKQILEAVSYLHDLNISHRDLKPENILISAVSHGKSSVIKVTDFGLAKI-IGE-KEMATTLCGTPLYVAPEIIRNCLHGDGGAQVNTGYGK
||| ||.. . .|  ||..||.. | ||||||||||    |   .  ||.||||..|.   . .... | |.|  |.|||...        |. . |..|
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES--NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKR-------ANQQGGHDK

EVDVWSLGCILYILLSGRPPFDF--DHTNNFNLKLINQGLYNFSLPVWDVVTENAKDLIKKLLNVDPTKRIS-----TKGALSHDWF
 .|.||||...| .|.|.|||    | . .  .| | .| .....| |. ....|||||.|.| .|| ||..     ..  ..| ||
ACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase FHAK3.AA CAMK-Unique 199-472 27 4.4e-91 300.91 In-house 1-363 (363) Show / Hide 
Range on Protein: 199-472
Range on HMM: 1-363/363
Sequence Identity: 27% (102 aa)

YSIQGILGTGNFSVVKRCIRRDTGEVFAVKIIDKKKFWSQTKTRRQ------------------MESEVEILQKIKHPNIISIIDI----VQSDR-----
|    |.|.|||..|..|. | ||  .|.|.. |..   . | . |                   . |..|... .||||| . |.    .. ..     
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQT--HGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCD

----------YFYIVLELATGGELFEKIKQ--------------------KGRFSE--PEAKDTFKQILEAVSYLHDLNISHRDLKPENILISAV-----
          |.|||.|...||.||..| .                    .|.|||   ..   . ..|.||.|.|...| |||||.|||...       
LIIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNN

----SHGK--SSVIKVTDFGLAKIIGEKEMAT---TLCGTPLYVAP--------------EIIRNCLHGDGGAQVNTGYGKEV----DVWSLGCILYILL
    . ..   . ||..||||.. . ...| .   | ||||.|.||              |.|            . .|.  .    | |||| |.|..|
HHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVIN-----------MQCYDQQCSPASDIWSLGVIMYYML

SGRPPFDFDHTNN-------FNLKLINQGLY-NFSLPVWDV---VTENAKDLIKKLLNVDPTKRISTKGALSHDWF
.|.|||| .  .          .. | .| | ||. ..|..   ....|||..|....||| .|.| | .|.|.|.
CGCPPFDCECEDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase FHAK3.AA CAMKL 199-374 34 2.1e-76 243.27 In-house 1-205 (297) Show / Hide 
Range on Protein: 199-374
Range on HMM: 1-205/297
Sequence Identity: 34% (73 aa)

YSIQGILGTGNFSVVKRCIR-RDTGEVFAVKIIDKKKFWSQTKTRRQ-----------MESEVEILQKIK---HPNIISIIDIVQSDRY------FYIVL
| |   ||.|.|..|| ..  | |||  |.||||||| |  .....             . |..|.....   |||||.. .... ...      .|.|.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELATGGE--LFEKIKQK----GRFSEPEAKDTFKQILEAVSYLHDLNISHRDLKPENILISAVS-HGKSSVIKVTDFGLAKIIGE-----KEMATTLCGT
|.. |||  ||..|...    ||..|.||.  |.||..||.|.|...| |||.||||||..    .    .||..|||.. .. .      .. .| ||.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN----NIKIIDFGFSNMYRPCIFGPGQKLKTFCGS

PLYVAPEII
| | ||||.
PPYMAPEIF
Kinase FHAK3.AA CDPK 199-375 40 7.1e-72 219.78 In-house 1-187 (271) Show / Hide 
Range on Protein: 199-375
Range on HMM: 1-187/271
Sequence Identity: 40% (77 aa)

YSIQGILGTGNFSVVKRCIRR-DTGEVF-AVKIIDKKKFWSQTKTRRQMESEVEILQKIKHPNIISIIDIVQSDRYFYIVLE--LATGGELFEKIKQKGR
| | ..||.|.|..|.... .  |...  |.||| |..   . .   |.  |.||| .. ||||| |    | ....|||.|  . ||||||..|..||.
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQ-QQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGH

FSEPEAKDTFKQILEAVSYLHDLNISHRDLKPENILISAVSHGKSS----VIKVTDFGLAKIIGEK-----EMATTLCGTPLYVAPEIIR
|.| || ....||| ||.| |. || ||||||||||    |  ..|     ||| |.|..|. . .     .  .. ||||.|.|||...
FTEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILF--DSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQ
Kinase FHAK3.AA CDPK 390-472 45 1.1e-32 97.75 In-house 190-271 (271) Show / Hide 
Range on Protein: 390-472
Range on HMM: 190-271/271
Sequence Identity: 45% (38 aa)

YGKEVDVWSLGCILYILLSGRPPFDFDHTNNFNLKLINQGLYNFSLPVWDVVTENAKDLIKKLLNVDPTKRISTKGALSHDWF
| ...|.||.| ||||||.|.|||  .  .   .. .  | |.|  | || ....|||||.|.|..|| ||.|   || | ||
YNEKCDIWSCGVILYILLCGYPPFYGKNDQEI-MEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase FHAK3.AA CAMKL 390-472 34 4.9e-27 83.21 In-house 213-297 (297) Show / Hide 
Range on Protein: 390-472
Range on HMM: 213-297/297
Sequence Identity: 34% (30 aa)

YGKEVDVWSLGCILYILLSGRPPFDFDHTN-----NFNLKLINQGLYNFSLPVWDVVTENAKDLIKKLLNVDPTKRISTKGALSHDWF
.|..||.||.| ||| .. |. ||| |. |     |. ...  .    .  |.|  |   ..|||.|.|.|.|.||.. .  ..| |.
DGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase FHAK3.AA Pkinase_Tyr 199-404 24 5.8e-16 54.68 Pfam 1-205 (270) Show / Hide 
Range on Protein: 199-404
Range on HMM: 1-205/270
Sequence Identity: 24% (54 aa)

YSIQGILGTGNFSVVKRCIRR----DTGEVFAVKIIDKKKFWSQ-TKTRRQMESEVEILQKI-KHPNIISIIDIVQ-SDRY--FYIVLELATGGELFEKI
 ..   || |.| .|.... .    .|.   |||.. | .  ..    |. . .|..|. .. .||||.. . ..   ..    |||.|.. .| | .  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQN-CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

KQ----KGRFSEPEAKDTFKQILEAVSYLHDLNISHRDLKPENILISAVSHGKSSVIKVTDFGLAKIIGEKEMA-TTLCGTPL---YVAPEIIRNCLHGD
..    |.... ..  .   || .. .||.. |. ||||   |.|..      . |.|..|||||. | ...   ..  |..|     ||| |...    
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE-----NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK---

GGAQVNTGYGKEVDVWSLGCILY
        .  . |||| |  ..
--------FTTKSDVWSFGVLMW
Kinase FHAK3.AA TyrKc 199-471 20 1.2e-14 13.89 SMART 1-280 (280) Show / Hide 
Range on Protein: 199-471
Range on HMM: 1-280/280
Sequence Identity: 20% (64 aa)

YSIQGILGTGNFSVVKRCIRRDTGEVFAVKIIDKKKFWSQTKTRRQMESEVEILQKI--KHPNIISIIDIVQSD-------RYFYIVLELATGGELFEKI
 .   .|| |.| .| ... .   .  ||| . . .       |. . .| .|. |.  .||||. .. .. ..          .||.|.. .| | . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

KQKGR-FSEPEAKDTFKQILEAVSYLHDLNISHRDLKPENILISAVSHGKSSVIKVTDFGLAKIIGEK-------EMATT----LCGTPL---YVAPEII
. ... .. ..  .   || .  .|||. |. ||||   |.|...       ..|..||||.. |...       .. ..     . |.|     ||| |
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

RNCLHGDGGAQVNTG-YGKEVDVWSLGCILY-ILLSGRPPFDFD----HTNNFNLKLINQGLYNFSLPV--WDV----VTENAKDLIKKLLNVDPTKRIS
            |.| .  . |||| |  .. |.  | .|   .     .|   .... || .    |     .     ..   ...|.  . || .|  
------------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MSFVCCPDEMYQIMKQCWHEDPEDR-P

TKGALSHDW
|  .. ...
TFSEIHECF