Gene FHAK4 (Slime mold)

FHAK4

Species: Slime mold
Alias: FHAK4, DDB0220031, DdisK040, pkgA
External Links: DictyBase Link ,
Annotation:

Classification

Group: CAMK
Family: RAD53

Sequence

Name Sequence Type Origin Length Description Download
FHAK4.AA Protein None 595 None Fasta, JSON
FHAK4.kin_dom Protein Kinase Domain None 261 None Fasta, JSON

Protein domain

Protein domains of FHAK4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
FHA FHAK4.AA FHA 116-187 27 3.8e-16 64.77 Pfam 1-73 (73) Show / Hide 
Range on Protein: 116-187
Range on HMM: 1-73/73
Sequence Identity: 27% (22 aa)

IILGRSKGVCNYTFT-SPT-VSGKHCKI-YRDPTVKSRNVAFVDD--TSTNGTFI--NNEVIGKGSKILIENGCEISVI
...||.   |.. .  .|. ||..|| | ..|..     . .. |  .||||||.  |.. |..| .. . .|..|.. 
WTIGRD-PDCDIVLDNDPSFVSRHHCEIRRYDNG-----RWYIRDLGCSTNGTFVTGNGQRIQPGEPHRLHHGDRIRFG
FHA FHAK4.AA FHA 115-170 25 8.1e-13 49.83 SMART 1-49 (49) Show / Hide 
Range on Protein: 115-170
Range on HMM: 1-49/49
Sequence Identity: 25% (15 aa)

SIILGRSKGVCNYTFTSPTVSGKHCKIYRDPTVKSRNVAFVDDTS---TNGTFINNEVI
 ...||..  |..  ..|..| .|| |. |..       .. | .   ||||..|.. .
TWTIGRHS--CDIQLPHPSISRHHCQIR-DGD-------YIIDLGEHSTNGTYVNGRRV
Kinase FHAK4.AA RAD53 218-479 51 2.2e-208 627.51 In-house 1-305 (305) Show / Hide 
Range on Protein: 218-479
Range on HMM: 1-305/305
Sequence Identity: 51% (157 aa)

YDLREVLGTGNFASVRLGVEKETGNKYAIKIIDKKKMS---MTS-KRKDSLMDEVNVLTKVKHQNIISIKEVFET-QKNLYLVLELVTGGELFDKIV-SE
|.....||.|||..|.|..||.|..|.|||||||||..   |.. |..|..|.||..|.|..|..||.|...|.| ||..|.||||.||||||.||| ..
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

RK---FQEDTCRYILKQLCDSVRYLHSNGIAHRDLKPENILLATPN----------------SFLLKISDFGLSRAMDEGTYMKTMCGTPQYVAPEILTK
|.   |.||||.|...|.||.|.|||.|||.||||||||||.....                |||.||.|||||....||..||||||||||||||..|.
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVITS

GER------------EGYGKSVDLWSIGVITYILLCGFPPFGDP-----QTKDFFEKIKN-GGFSFPSPYWDEISDEAKSLIKNLIKVDVEKRFTIDQAL
. .            .||.|.||.||.|.|.||.|||.|||.|.     .....||.||| | ..||.||||.||.|||.|||....||.|||.|||.||
KGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEAL

NHPWF
||||.
NHPWM
Kinase FHAK4.AA CAMK1 218-479 48 3.6e-167 490.04 In-house 1-276 (276) Show / Hide 
Range on Protein: 218-479
Range on HMM: 1-276/276
Sequence Identity: 48% (135 aa)

YDLREVLGTGNFASVRLGVEKET---GNKYAIKIIDKKKMSMTSKR--KDSLMDEVNVLTKV---KHQNIISIKEVFETQKNLYLVLELVTGGELFDKIV
| .....|.| |. |.|...|||   | .||||.|||||.  ....  ...|. |.....||   .|.|||...|..|. . .|||.||||||||||.||
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

SERKFQEDTCRYILKQLCDSVRYLHSNGIAHRDLKPENILLATP-NSFLLK--ISDFGLSRAMDEGT-YMKTMCGTPQYVAPEILT-KGEREGYGKSVDL
   .. |.  | | ||... | |.||.||.||||||||.|.... . . .|  |.|||||.  |..  .|||.|||| |||||.|. |   ..|.|..|.
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKK-DKPYDKACDM

WSIGVITYILLCGFPPFGDPQ-TKDFFEKIKNGGFSFPSPYWDEISDE-AKSLIKNLIKVDVEKRFTIDQALNHPWF
|||||||||||||.||| |    .  |||||.. . ||||.||.|||. || .||....|| .||.|..|.|||||.
WSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase FHAK4.AA CAMK 223-479 30 6.5e-139 450.61 In-house 1-425 (425) Show / Hide 
Range on Protein: 223-479
Range on HMM: 1-425/425
Sequence Identity: 30% (129 aa)

VLGTGNFASVRLGVEKETG------------NKYAIKIIDKKKMSM------------------------TSKRKDSLMDEVNVLTK-------VKHQNI
.||.|.|. |.|...|.|.             |.|||||||||..                         . | ..... |.... |       ..| ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

ISIKEVFE------------TQKN--------LYLVL---ELVTGGEL----FDKIVSE---------------RKFQEDTCRYILKQLCDSVRYLHSNG
|.. ||.|            | ..        .|.|.   |...||||    ||.||.                ..|.|. .|.. .|.|. |.|.||..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IAHRDLKPENILLATPNS---------------FLLKISDFGLSRAMDE------------------------GTYMKTMCGTPQYVA-PEILTK-----
|.||||||||||| . |.               . .||.|||... .|.                        |  |||.|||| |.| ||.| .     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

------GEREGYGKSVDLWSIGVITYILLCGFPPFGDP-------------QTKDFFEKIKNGGFSFPSPY------------WDEISDE--------AK
      .|...||...| ||.|||.||.|||.||| ..               .. ||||..| ..||.||            ||.||||        .|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

SLIKNLIKVDVEKRFTIDQALNHPWF
.||... .|| |||.||.|.|||||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase FHAK4.AA Ciliate-E2a 218-479 42 3.5e-123 364.41 In-house 1-275 (275) Show / Hide 
Range on Protein: 218-479
Range on HMM: 1-275/275
Sequence Identity: 42% (118 aa)

YDLREVLGTGNFASVRLGVEKETGNKYAIKIIDKKKMSMTSKRKDSLMDEVNVLTKVKHQNIISIKEVFETQKNLYLVLELVTGGELFDKIVSERKFQED
|..  ..|.|||.||.|   |.|| ..|.|...| ||. . | | ..|.|.| . ...| ||| . ||.|. .|.|||.|.. ||||.|||.   .|.| 
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE

--TCRYILKQLC-DSVRYLHSNGIAHRDLKPENILLA--TPNS---FLLKISDFGLSRAM--DEGTYMKTMCGTPQYVAPEILTKGE---REGYGKSVDL
    . |..||  . . |.|...| ||||||||||.    .||   . .||.||||..    ||. ||...|||| |||||.|   |   .. |....|.
IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDM

WSIGVITYILLCGFPPFGDPQTKDFFEKIKNGGFSFPSPY-WDEISDEAKSLIKNLIKVDVEKRFTIDQALNHPWF
||.||| |||||| |||    ... ....|.  ..| .|  | ..|.|.| |.| . ..| .||.|. ||||||||
WSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase FHAK4.AA DCAMKL 218-479 43 5e-116 362.59 In-house 1-279 (279) Show / Hide 
Range on Protein: 218-479
Range on HMM: 1-279/279
Sequence Identity: 43% (124 aa)

YDLREVLGTGNFASVRLGVEKETG-NKYAIKI-----------------IDKKKMSMTSKRKDSLMD-EVNVLTKVKHQNIISIKEVFETQKNLYLVLEL
|..  . | ||||.| . ...|||  ||| ||                 |||.|.    | |  . | || .. |.|| .||.. |...|....|||.|.
YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKC----KGKEHMIDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVMEY

VTGGELFDKIVSERKFQEDTCRYILKQLCDSVRYLHSNGIAHRDLKPENILLAT--PNSFLLKISDFGLSRAMDE-GTYMKTMCGTPQYVAPEILTKGER
|.|| ||| |.. .|| |   . .. .||   .|||. .| |||.|||| |.      .. ||  ||||   ...    . | |||| ||||||| .   
VQGGDLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILME---

EGYGKSVDLWSIGVITYILLCGFPPFGDP--QTKDFFEKIKNGGFSFPSPYWDEISDEAKSLIKNLIKVDVEKRFTIDQALNHPWF
 |||  || |..|||.||||||||||  |  .  . |..|  | |.||.||||.||| || ||... .||.|||.|  | . ||| 
TGYGCKVDIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase FHAK4.AA S_TKc 218-479 37 3e-112 380.15 SMART 1-231 (231) Show / Hide 
Range on Protein: 218-479
Range on HMM: 1-231/231
Sequence Identity: 37% (105 aa)

YDLREVLGTGNFASVRLGVEKETGNKYAIKIIDKKKMSMTSKRKDSLMDEVNVLTKVKHQNIISIKEVFETQKNLYLVLELVTG--GELFDKIVSERK--
|.. ...| | |..|.....|.|| ..|||||.           .... |...| | .| ||. ...||.. ..||.|.|.. |  |.||| |.. ..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----FQEDTCRYILKQLCDSVRYLHSNGIAHRDLKPENILLATPNSFLLKISDFGLSRAMDEGTYMKTMCGTPQYVAPEILTKGEREGYGK-SVDLWSIG
    | | ..|....|.|. . |.||.|| ||||||||||| .     .||.||||.| .      .|.|||| |.|||.|      |||| ..| ||.|
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL------TTFCGTPWYMAPEVL------GYGKCKCDWWSCG

VITYILLCGFPPFGDPQTKDFFEKIKNGGFSFPSPYWDEISDEAKSLIKNLIKVDVEKRFTIDQALN-------HPWF
.| |..||| |||   | .  |.||.              |.|||..|... ..| ||| |. .||.       ||||
CILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase FHAK4.AA CAMKL 218-479 36 3.3e-112 359.42 In-house 1-297 (297) Show / Hide 
Range on Protein: 218-479
Range on HMM: 1-297/297
Sequence Identity: 36% (110 aa)

YDLREVLGTGNFASVRLGVE-KETGNKYAIKIIDKKKMS-MTSKRKD------SLMD----EVNVLTKVK---HQNIISIKEVFETQKN------LYLVL
|.. ..||.|.|. |.|..  . || |.|||||||||..  . ..|       . ..    |.. . ...   |.|||.. ||.||...      .|||.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELVTGGE--LFDKIVSE----RKFQEDTCRYILKQLCDSVRYLHSNGIAHRDLKPENILLATPNSFLLKISDFGLSRAMDE-----GTYMKTMCGTPQYV
|.. |||  |||.||..    ....|. .| . .|... | |.||.||.|||.|||||||   ..  .||.|||.|  ...     |  .|| ||.| | 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEILTKGEREGYGKSVDLWSIGVITYILLCGFPPFGDP--------QTKDFFEKIKNGGFSFPSPYWDEISDEAKSLIKNLIKVDVEKRFTIDQALNHP
||||. ..... .|. || ||.||| | ..||  || |.         .  ...||. | . .| .|  ..| ....||. . .|. |||.||.| .|||
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWY--HVS-DCRDLIRKMLQVNPEKRPTIHQIMNHP

WF
|.
WM
Kinase FHAK4.AA CDPK 218-479 42 1e-110 340.72 In-house 1-271 (271) Show / Hide 
Range on Protein: 218-479
Range on HMM: 1-271/271
Sequence Identity: 42% (118 aa)

YDLREVLGTGNFASVRLGVEK-ETGNKY-AIKIIDKKKMSMTSKRK-DSLMDEVNVLTKVKHQNIISIKEVFETQKNLYLVLE--LVTGGELFDKIVSER
|.. .|||.|.| .||....|  |. .  |.||| |.. .   | . ...  |...| .  | ||| | |... .|| |.|.|  ..|||||||.|....
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKD--KEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKG

KFQEDTCRYILKQLCDSVRYLHSNGIAHRDLKPENILLAT--PNS---FLLKISDFGLSRAMDE-----GTYMKTMCGTPQYVAPEILTKGEREGYGKSV
.|.|   .|| .|.   | | |||.| ||||||||||. .  ..|   . .|. |.|.|.  |      . .|...|||| |.|||.| |     | ...
HFTEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQK---K-YNEKC

DLWSIGVITYILLCGFPPFGDPQTKDFFEKIKNGGFSFPSPYWDEISDEAKSLIKNLIKVDVEKRFTIDQALNHPWF
|.||.||| |||||| |||.    .. .||.|.| .||  | ||.|||||| ||.... .| .||.. .|||.||||
DIWSCGVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase FHAK4.AA RSK 220-479 33 4.3e-103 348.79 In-house 1-278 (278) Show / Hide 
Range on Protein: 220-479
Range on HMM: 1-278/278
Sequence Identity: 33% (94 aa)

LREV--LGTGNFASVRLGVEKETGNKYAIKIIDKKKMSMTSKRKDSLMDEVNVLTKVK-HQNIISIKEVFETQKNLYLVLELVTGGELFDKIVSERK---
|..   .| | .  .|  . . ||  || |...|.|.  . |     | |.|.|  .. |..|.. ...|.|.. |||..|.. |||||...  |.    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FQEDTCRYILKQLCDSVRYLHSNGIAHRDLKPENILLATPN-SFLLKISDFGLSRAM--DEGTYMKTMCGTPQYVAPEILTKGE-REGYGKSVDLWSIGV
| ||...... ..   |..||. || ||||||||||..  . .  .|..|||... .  |..  ..| |.| .|.|||.|.... ..|..|..|.|| ||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

ITYILLCGFPPFGD---PQTKDFFEKIKNGGFSFPSPYWDEISDEAKSLIKNLIKVDVEKRFT-----IDQALNHPWF
. | .| |.|||      . |. ...|..| ||...| |...|.|||.||. . ..| .|| .     ... ..||||
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase FHAK4.AA Pkinase 218-479 33 3.9e-102 350.41 Pfam 1-293 (293) Show / Hide 
Range on Protein: 218-479
Range on HMM: 1-293/293
Sequence Identity: 33% (99 aa)

YDLREVLGTGNFASVRLGVEKETGNKYAIKIIDKKKMSMTSKRKDSLMDEVNVLTKVKHQNIISIKEVFETQKNLYLVLELVTGG----ELFDKIV--SE
| . ...| |.|..|.....| || ..|.|||.|.. ..  .. . .  |. .. ...| ||. ....||. ...|.|.|.. ||    .||| |   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RKF--QEDTCRYILKQLCDSVRYLHSNGIAHRDLKPENILLATPNSFL---LKISDFGLSRA--MDEGTYMKTMCGTPQYVAPEILTKGEREGYGKSVDL
..|  .|..|. ...|..  . |.||.|| ||||||||||.   |  .   .||.||||..      .. |.| |||| |.|||..   ....||..|| 
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR--GGQYYGPKVDM

WSIGVITYILLCGFPPFGDP------QTKDFFEKIKNGGFSFPSPYWDEIS-----------------DEAKSLIKNLIKVDVEKRFTIDQALNHPWF
||.|.| |..||| ||| .         .  ...|. . ..|..|.|..||                 .|.|..||.....| .|| |..|.|.||||
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase FHAK4.AA Ciliate-E2 218-479 29 6e-101 341.68 In-house 1-365 (365) Show / Hide 
Range on Protein: 218-479
Range on HMM: 1-365/365
Sequence Identity: 29% (112 aa)

YDLREVLGTGNFASVRLGVEKETGNKYAIKIIDKKK-----------------MSMTSKRKDSLMDEVNVLTKVK----------------HQNIISIKE
|.. ...|.|||.||...  .......|||||| .|                  .|  . . ... | ... ...                | ||| ..|
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

VFE--TQKNLYLVLELVTGGELFDKIVSERKFQ-----------EDTCRYILKQLCD---------------SVRYLHSNG-IAHRDLKPENILLATPNS
.|.  ...|.|||.|.. ||.||| | . .|..           |  ..|| ||...                ..||||.. | |||.||||||.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

FLLKISDFGLSR-----------------AMDEG-------TYM---------KTMCGTPQYVAPEILTKGE------REGYGKSVDLWSIGVITYILLC
  .||.|||||.                  |. .       .||         .| |||| |.||||| ...      ..||....|.||.||| |..|.
--IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

GFPPFGDPQTKDFFEKIKNGGFSFPSP--------------YWDEISDEAKSLIKN----LIKVDVEKRFT-IDQALNHPWF
| |||        ...||.. ..||.|               |...|.|.| |||.    ....| |||.| ..|.||||||
GKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase FHAK4.AA CAMK-Unique 218-479 27 1.5e-95 315.87 In-house 1-363 (363) Show / Hide 
Range on Protein: 218-479
Range on HMM: 1-363/363
Sequence Identity: 27% (99 aa)

YDLREVLGTGNFASVRLGVEKETGNKYAIKIIDK-----KKMSM-----------TSKRKDSLMDEVNVLTKVKHQNIISIKEV----FETQK-------
|.. ...|.|||  |. .  .||| |.|.|.. |     ||.              . |  .|. |.... .|.|.||| . ..    |.. |       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------NLYLVLELVTGGELFDKIVS--------------------ERKFQE--DTCRYILKQLCDSVRYLHSNGIAHRDLKPENILLATP-------
        ..|.|.|...||.|||.|..                    ...| |     . |  .|   | |.||..| |||||.|||.. ..       
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

-------NSFLLKISDFGLSRAMD-EGTY--MKTMCGTPQYVAP--------------EILTKGEREGYGKSV----DLWSIGVITYILLCGFPPFGDPQ
       .   .|..||||..  .    .  |.|||||| |.||              |..   .. .|.  .    |.||.|||.|..||| |||  . 
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVI---NMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCEC

TK--------DFFEKIKNGGF-SFPSPYWDE---ISDEAKSLIKNLIKVDVEKRFTIDQALNHPWF
 .          ||.|. |.. .|....|.    ||.|||...|.. .||. .| .. ..| |.|.
EDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase FHAK4.AA Pkinase_Tyr 218-377 23 1.2e-20 70.56 Pfam 1-171 (270) Show / Hide 
Range on Protein: 218-377
Range on HMM: 1-171/270
Sequence Identity: 23% (42 aa)

YDLREVLGTGNFASVRLGVEK----ETGNKYAIKIIDKKKMSMTSKR--KDSLMDEVNVLTKV-KHQNIISIKEVFE-TQKN--LYLVLELVTGGELFDK
  . ..|| |.| .|..|. |    .|. . |.|.. |   . ...   ....| |......  .|.||..   |    ..   .|.|.|.. .| | | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

IVS----ERKFQEDTCRYILKQLCDSVRYLHSNGIAHRDLKPENILLATPNSFLLKISDFGLSRAM-DEGTY-MKT
  .    ....   .   .  | ..   ||.|... ||||   |.|..   ..  ||.||||.|.. ....|  |.
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE--NNVVKICDFGLARDIYNDDYYYRKR
Kinase FHAK4.AA TyrKc 218-479 24 2.4e-17 57.82 SMART 1-280 (280) Show / Hide 
Range on Protein: 218-479
Range on HMM: 1-280/280
Sequence Identity: 24% (72 aa)

YDLREVLGTGNFASVRLGVEKETGNKYAIKIIDKKKMSMTSKRKDSLMDEVNVLTKV--KHQNIISIKEVFETQ-------KNLYLVLELVTGGELFDKI
  | ..|| |.|  |..|. |    . |.| . . .       .  .|.| ....|.  .|.||. .  |  .|       . |..|.|.. .| | | .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

VSERK-FQEDTCRYILKQLCDSVRYLHSNGIAHRDLKPENILLATPNSFLLKISDFGLSRAMDEG-------TYMKTMC--GTPQ-----YVAPEILTKG
 . |. .. ..  ..  | ..  .||||... ||||   |.|.. ..    |||||||||. ...        | ...   |.         ||| .   
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---

EREG-YGKSVDLWSIGVITY-ILLCGFPPFGD-----PQTKDFFEKIKNGGFSFPSPY-WDE-----ISDEAKSLIKNLIKVDVEKRFTIDQALNHPWF
 ..| .    | || ||  . |.  | .|  .        .. .|..|.|.   . |.   .      .||  ...|   . | |.| |  .   |  |
-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF