Gene MLCK-A (Slime mold)

MLCK-A

Species: Slime mold
Alias: MLCK-A, mlkA, DDB0214815, DdisK028, MLCK
External Links: DictyBase Link ,
Annotation:

Classification

Group: CAMK
Family: CAMK1

Sequence

Name Sequence Type Origin Length Description Download
MLCK-A.AA Protein None 295 None Fasta, JSON
MLCK-A.kin_dom Protein Kinase Domain None 258 None Fasta, JSON

Protein domain

Protein domains of MLCK-A.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MLCK-A.AA CAMK1 8-265 53 9.3e-208 610.09 In-house 1-276 (276) Show / Hide 
Range on Protein: 8-265
Range on HMM: 1-276/276
Sequence Identity: 53% (148 aa)

YEFKEELGRGAFSIVYLGENKQT---KQRYAIKVIN-KSELGKDYE---KNLKMEVDILKKV---NHPNIIALKELFDTPEKLYLVMELVTGGELFDKIV
|||..|.||||||.|||...|.|   .. ||||.|. |. . |...   ..|..|..|.|||   .|||||...| .......||||||||||||||.||
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

EKGSYSEADAANLVKKIVSAVGYLHGLNIVHRDLKPENLLLKSKENHLEVA--IADFGLSKIIGQTL-VMQTACGTPSYVAPEVLNA---TGYDKEVDMW
|||.|.| ||....|.|.|||.|.| ..||||||||||||...|... ...  |||||||||...   .|.||||||.|||||||.    ..|||..|||
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMW

SIGVITYILLCGFPPFYGDT-VPEIFEQIMEANYEFPEEYWGGISKE-AKDFIGKLLVVDVSKRLNATNALNHPWL
||||||||||||.||||...  .|.||.|... ||||. .|. ||.. ||||| ..|.|| .||.... .|||||.
SIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase MLCK-A.AA CAMK 13-265 30 1.6e-140 455.89 In-house 1-425 (425) Show / Hide 
Range on Protein: 13-265
Range on HMM: 1-425/425
Sequence Identity: 30% (129 aa)

ELGRGAFSIVYLGENKQTK------------QRYAIKVINKSELGKDY--------------------------EKNLKMEVDILKK-------VNHPNI
.||||.|..|.|...|.|.            |..|||.|.|. | ..                           .||.. |..|.||       ..||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IALKELFD------------TPEK--------LYLVM---ELVTGGEL----FDKIVEKGS---------------YSEADAANLVKKIVSAVGYLHGLN
| | | ..            | .|        .|.||   |...||||    ||.|||.|.               ..|..|. ... |.||| |.| .|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHRDLKPENLLLKSKENH--------------LEVAIADFGLSKIIGQ------------------------TLVMQTACGTPSYVA-PEVLNA-----
||||||||||.|| .....                . |.|||..... .                        .  |.| ||||.|.| |||||      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------TGYDKEVDMWSIGVITYILLCGFPPFYGD-------------TVPEIFEQIMEANYEFPEEY------------WGGISKE--------AK
         ..|....||||.|||.||.|||.||||||             . .|.||.||...|.||..|            |..||.|        .|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DFIGKLLVVDVSKRLNATNALNHPWL
|.| |.|.|| .||.... .|||||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase MLCK-A.AA RAD53 8-265 41 9.5e-140 419.2 In-house 1-305 (305) Show / Hide 
Range on Protein: 8-265
Range on HMM: 1-305/305
Sequence Identity: 41% (126 aa)

YEFKEELGRGAFSIVYLGENKQTKQRYAIKVINK---S---ELGKDYEKNLKMEVDILKKVNHPNIIALKELFDTP-EKLYLVMELVTGGELFDKIV-EK
| . .|||.|.|..|.|. .| | |..||| |.|   .       . ....  || ||||.|||.||.... |||| . .|.|.||.||||||.|||  |
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

GS---YSEADAANLVKKIVSAVGYLHGLNIVHRDLKPENLLLKSKENHL---------------EVAIADFGLSKIIGQTLVMQTACGTPSYVAPEVLNA
.    ..|...  . . .. || ||| ..|.|||||||| |.....                   . |.||||||..| . .|.| ||||.||||||.  
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVITS

---------------TGYDKEVDMWSIGVITYILLCGFPPFY-GDTV----PEIFEQIME-ANYEFPEEYWGGISKEAKDFIGKLLVVDVSKRLNATNAL
               .|| |.||.||.|.|.||.|||.|||  ..|     . .||||   ..|.|| .||  || ||||.| ..|.||. ||... .||
KGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEAL

NHPWL
||||.
NHPWM
Kinase MLCK-A.AA CDPK 8-265 44 7.79999999999e-129 397.16 In-house 1-271 (271) Show / Hide 
Range on Protein: 8-265
Range on HMM: 1-271/271
Sequence Identity: 44% (121 aa)

YEFKEELGRGAFSIVYLGENK-QTKQRY-AIKVINKSELGKDYE-KNLKMEVDILKKVNHPNIIALKELFDTPEKLYLVME--LVTGGELFDKIVEKGSY
| .|..||.|.|. |... .| .|.|.  |.|.|.||.. .  . .....|..|||.  ||||| . | .      |.|||  ..|||||||.|.|||..
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF

SEADAANLVKKIVSAVGYLHGLNIVHRDLKPENLLLKSKENHL----EVAIADFGLSKIIGQT-----LVMQTACGTPSYVAPEVLNATGYDKEVDMWSI
.| .||. ...|.||| | |  |||||||||||.|..||..      .. . |.|.||. .|       .| . |||| |.|||||.   |....| ||.
TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCDIWSC

GVITYILLCGFPPFYGDTVPEIFEQIMEANYEFPEEYWGGISKEAKDFIGKLLVVDVSKRLNATNALNHPWL
||| |||||| |||||..  ||.|.... .|.|  . |  ||.|||| | |.|..|  ||. |  ||.||| 
GVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase MLCK-A.AA Ciliate-E2a 8-265 40 2e-119 353.19 In-house 1-275 (275) Show / Hide 
Range on Protein: 8-265
Range on HMM: 1-275/275
Sequence Identity: 40% (113 aa)

YEFKEELGRGAFSIVYLGENKQTKQRYAIKVINKSELGKDY--EKNLKMEVDILKKVNHPNIIALKELFDTPEKLYLVMELVTGGELFDKIVEKGSYSEA
|.|. ..| |.|  ||| . |||....|.|...|  .  .   ......|..|.....||||| | | . .   .|||||.. ||||.|||...... | 
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE

--DAANLVKKIVS-AVGYLHGLNIVHRDLKPENLLLK--SKENH--LEVAIADFGLSKII--GQTLVMQTACGTPSYVAPEVLNATG------YDKEVDM
  ... . ... . .. |.| .||.||||||||.|.|  ||..   ... |.||||.. |   .  .| . |||| ||||||||         ||. .||
IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDM

WSIGVITYILLCGFPPFYGDTVPEIFEQIMEANYEFPEEY-WGGISKEAKDFIGKLLVVDVSKRLNATNALNHPWL
||.||| |||||| |||.| |. ||..|. . .. |     |  .|||.||.. |.|..| .||..|. |||||| 
WSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase MLCK-A.AA DCAMKL 8-265 41 1.4e-116 364.33 In-house 1-279 (279) Show / Hide 
Range on Protein: 8-265
Range on HMM: 1-279/279
Sequence Identity: 41% (117 aa)

YEFKEELGRGAFSIVYLGENKQTK-QRYAIKV-----------------INKSELGKDYEKNLKMEVDILKKVNHPNIIALKELFDTPEKLYLVMELVTG
|.     | | |..|..  ...|. ..|| |.                 |.|. . |  |.   .|| |..|..||.|| | | .||....|||||.|.|
YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKC-KGKEHMIDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVMEYVQG

GELFDKIVEKGSYSEADAANLVKKIVSAVGYLHGLNIVHRDLKPENLLLKS-KENHLEVAIADFGLSKIIGQ-TLVMQTACGTPSYVAPEVLNATGYDKE
| ||| |.| . ..| ||| .. .. .|  ||| .||||||.||||||..      ...  .|||| ... .   .. | |||| |||||.|. |||  .
GDLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILMETGYGCK

VDMWSIGVITYILLCGFPPFYGD--TVPEIFEQIMEANYEFPEEYWGGISKEAKDFIGKLLVVDVSKRLNATNALNHPWL
||.|..|||.|||||||||| .      | |.|||.. .|||  || .||  ||| | ..|.||. ||  |   . ||| 
VDIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase MLCK-A.AA CAMK-Unique 8-265 29 1.9e-116 385.95 In-house 1-363 (363) Show / Hide 
Range on Protein: 8-265
Range on HMM: 1-363/363
Sequence Identity: 29% (108 aa)

YEFKEELGRGAFSIVYLGENKQTKQRYAIKVINKSELGKDYEKN------------------LKMEVDILKKVNHPNIIALKEL----FDTPE-------
|.. . .| |.|..|| . .. |.  .|.|...|   | .  |                   || |..|.|.|.||||| | .     | ...       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------KLYLVMELVTGGELFDKIVE--------------------KGSYSE--ADAANLVKKIVSAVGYLHGLNIVHRDLKPENLLLKSKEN-----
        ..|.|||...||.|||.|..                    .|..||  .|..... ...||| |.| ..|||||||.||..... ..     
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

--------HLEVAIADFGLSKIIG--QTL-VMQTACGTPSYVAP--------------EVLNATGYDKEV----DMWSIGVITYILLCGFPPFYGDTVP-
         . . ..||||.. .   .   .||| ||||.|.||              ||.|. .||  .    | ||.|||.|..||| |||.... . 
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------EIFEQIMEANY-EFPEEYWGG---ISKEAKDFIGKLLVVDVSKRLNATNALNHPWL
       |||| |. ..| .|....|.|   ||.|||||. ....||...|..| ..| |.|.
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase MLCK-A.AA S_TKc 8-265 38 5.1e-115 389.32 SMART 1-231 (231) Show / Hide 
Range on Protein: 8-265
Range on HMM: 1-231/231
Sequence Identity: 38% (105 aa)

YEFKEELGRGAFSIVYLGENKQTKQRYAIKVINKSELGKDYEKNLKMEVDILKKVNHPNIIALKELFDTPEKLYLVMELVTG--GELFDKIVEKGS----
||. ...|.|||. ||.. .| |....|||.|.         .... |..|||| .||||. |.. |.. ..||.|||.. |  |.||| |...|.    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--YSEADAANLVKKIVSAVGYLHGLNIVHRDLKPENLLLKSKENHLEVAIADFGLSKIIGQTLVMQTACGTPSYVAPEVLNATGYDK-EVDMWSIGVITY
  ..| .|. ... |..|. |.| ..|.||||||||.|| .     .. |.||||....       | |||| |.|||||   ||.| ..|.||.|.| |
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ILLCGFPPFYGDTVPEIFEQIMEANYEFPEEYWGGISKEAKDFIGKLLVVDVSKRLNATNALN-------HPWL
..||| |||.  .. ..|..|.              |.|||||| |.|..| .||. |  ||.       |||.
EMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase MLCK-A.AA CAMKL 8-265 36 1.6e-107 344.22 In-house 1-297 (297) Show / Hide 
Range on Protein: 8-265
Range on HMM: 1-297/297
Sequence Identity: 36% (109 aa)

YEFKEELGRGAFSIVYLGEN-KQTKQRYAIKVINKSELGKDYEKN-------------LKMEVDILKKVN---HPNIIALKELFDTPEK------LYLVM
|.. ..||.|.|. | |... . |....|||.|.|. . .|  ..             .. |. |.|..|   ||||| | | ..|||.      .||||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELVTGGE--LFDKIVEK----GSYSEADAANLVKKIVSAVGYLHGLNIVHRDLKPENLLLKSKENHLEVAIADFGLSKIIG-Q----TLVMQTACGTPSY
|.. |||  |||.||..    |. .| .|  . . ||||| |.| ..|||||.||||.|| .. |.  . |.|||.| ..  .       . | ||.|.|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

VAPEVLNA--TGYD-KEVDMWSIGVITYILLCGFPPFYGDTVP-------EIFEQIMEANYEFPEEYWGGISKEAKDFIGKLLVVDVSKRLNATNALNHP
 |||...   . || ..||.||.||| | ..||  || .||..       . ...||.  |..|   |  .| ...|.| |.|.|. .|| .. . .|||
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPI--WYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHP

WL
|.
WM
Kinase MLCK-A.AA Pkinase 8-265 34 9.5e-105 359.09 Pfam 1-293 (293) Show / Hide 
Range on Protein: 8-265
Range on HMM: 1-293/293
Sequence Identity: 34% (103 aa)

YEFKEELGRGAFSIVYLGENKQTKQRYAIKVINKSELGKDYEKNLKM--EVDILKKVNHPNIIALKELFDTPEKLYLVMELVTGG----ELFDKIV--EK
|.... .|.|.|. ||.. .| | ...|.|.|.|..  .. ....    |. |.|..|||||. |.. | .. ..|.|||.. ||    .||| |   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GSY--SEADAANLVKKIVSAVGYLHGLNIVHRDLKPENLLLKSKENHL--EVAIADFGLSKI--IGQTLVMQTACGTPSYVAPEVLN-ATGYDKEVDMWS
|..  || .. . .. |.... |.|  .|.||||||||.|.. ...|.   | |.||||.|   .     |.| |||| |.||||.. ...|...|||||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

IGVITYILLCGFPPFYGD------TVPEIFEQIMEANYEFPEEYWGGIS-----------------KEAKDFIGKLLVVDVSKRLNATNALNHPWL
.|.| |..||| |||.|.      .  .....||.. ..|....|  ||                 .|.|||| ..| .| .||..|. .|.|||.
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase MLCK-A.AA PSK 8-265 41 7e-103 329.64 In-house 1-258 (258) Show / Hide 
Range on Protein: 8-265
Range on HMM: 1-258/258
Sequence Identity: 41% (109 aa)

YEFKEELGRGAFSIVYLGENKQTKQRYAIKVINKSELGKDYEKNLKMEVDILKKVNHPNIIALKELFDTPEKLYLVMELVTGGELFDKIVEKGSYSEADA
|. |   |.| || |   | . |.| ||||.... .  ..  .    |  ||. | ||.|| | | |.| ...|.|||. ||||.|| || ||...| ||
YDIKALIGKGSFSRVVRVEHRVTRQPYAIKMVETKC--REGREFCENELNILRRVRHPYIIQLMEVFETQDRVYMVMEMATGGEMFDRIVAKGRFTERDA

ANLVKKIVSAVGYLHGLNIVHRDLKPENLLLKSKENHLEVAIADFGL--SKIIGQTLVMQTACGTPSYVAPEVLNATGYDKEVDMWSIGVITYILLCGFP
 .  . .. .. |||.| | ||||||||||     |   . | ||||  ..  ..  .|.| |||| |.|||||    | . |||| .|||.|||. |. 
TRVLQMVLDGMRYLHALRITHRDLKPENLLYYHPGNESKIMITDFGLAYQRKKSNDWMMKTTCGTPEYIAPEVLLRKPYTQSVDMWAVGVIAYILMSGIM

PFYGDTVPEIFEQIMEANYEFPEEYWGGISKEAKDFIGKLLVVDVSKRLNATNALNHPWL
||  |    .. .|. ..| .  ..| ..|. ||||| |||... ..|. |. |. |||.
PFDDDCRTRLYRHILTGKYNYYGQPWPSVSHLAKDFIDKLLEINQGERMTASQAMKHPWV
Kinase MLCK-A.AA RSK 10-265 34 5.2e-97 328.58 In-house 1-278 (278) Show / Hide 
Range on Protein: 10-265
Range on HMM: 1-278/278
Sequence Identity: 34% (96 aa)

FKEE--LGRGAFSIVYLGENKQTKQRYAIKVINKSELGKDY--EKNLKMEVDILKKVN-HPNIIALKELFDTPEKLYLVMELVTGGELFDKIVEKGS---
 |.   .| |.....   ....|.| || ||..|... .     .  . |..||. .. ||.|. |.. |.|..||||.||.. |||||... ....   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

YSEADAANLVKKIVSAVGYLHGLNIVHRDLKPENLLLKSKENH-LEVAIADFGLSKI--IGQTLVMQTACGTPSYVAPEVLN----ATGYDKEVDMWSIG
 || .|.    .||.|| .|| . |.|||||||| |. ... .  .. . |||..|.  . ..  ..| |.|  |.|||.|.      |.|| .| || |
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

VITYILLCGFPPFYG---DTVPEIFEQIMEANYEFPEEYWGGISKEAKDFIGKLLVVDVSKRLN-----ATNALNHPWL
|. | .| |.|||.|   ..  ||...|..... .. . |  .|.||||.| |.| .| .|||.     |   ..|||.
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase MLCK-A.AA TyrKc 8-265 22 4.8e-16 36.77 SMART 1-280 (280) Show / Hide 
Range on Protein: 8-265
Range on HMM: 1-280/280
Sequence Identity: 22% (67 aa)

YEFKEELGRGAFSIVYLGENKQTKQRYAIKVINKSELGKDYEKNLKMEVDILKKV--NHPNIIALKELFDTP-------EKLYLVMELVTGGELFDKIVE
 .....||.||| .||.|. |   .  |.|.....      .. .  |  |..|.  .||||..|     ..       | |..|||.. .| | | . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KGS-YSEADAANLVKKIVSAVGYLHGLNIVHRDLKPENLLLKSKENHLEVAIADFGLSKIIGQT-------LVMQTAC--GTPS-----YVAPEVLNATG
..   . .|  .    | .   |||  |..||||   | |....     | |.|||||. |.          .  ..   |. .       |||..|   
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YDKEVDMWSIGVITY-ILLCGFPPFYG-----DTVPEIFEQIMEANYEFPEEY-----WGGISKEAKDFIGKLLVVDVSKRLNATNALNHPWL
.  . | || ||  . |.  | .| .|      .  |..|.... ..  . ..       . ..|  . . .    | ..| . ..   |  .
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase MLCK-A.AA Pkinase_Tyr 8-158 30 2.2e-14 49.36 Pfam 1-161 (270) Show / Hide 
Range on Protein: 8-158
Range on HMM: 1-161/270
Sequence Identity: 30% (50 aa)

YEFKEELGRGAFSIVYLGENK----QTKQRYAIKVINKSELGKDY--EKNLKMEVDILKKV-NHPNIIALKELFD-TPEK--LYLVMELVTGGELFDKIV
 .| ..||.|||  ||.|. |    .||.  |.|.. |    ..    . .  |. |.|.  .||||. |        |   .|.|||.. .| | |   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

E----KGSYSEADAANLVKKIVSAVGYLHGLNIVHRDLKPENLLLKSKENHLEVAIADFGLSKII
.    |.. .  |  .    | ..  ||.  |..||||   | |...    . | |.||||.. |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE---NNVVKICDFGLARDI