Gene Cdk7 (Slime mold)

Cdk7

Species: Slime mold
Alias: DdisK047, cdcC, Cdk7, cdc2, mo15, DDB0191429
External Links: DictyBase Link ,
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDK7

Sequence

Name Sequence Type Origin Length Description Download
Cdk7.AA Protein None 360 None Fasta, JSON
Cdk7.kin_dom Protein Kinase Domain None 285 None Fasta, JSON

Protein domain

Protein domains of Cdk7.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Cdk7.AA CDK7 4-288 60 2.5e-279 754.43 In-house 1-288 (288) Show / Hide 
Range on Protein: 4-288
Range on HMM: 1-288/288
Sequence Identity: 60% (174 aa)

YNIEALIGEGTYGVVSRATVKATGQIVAIKKIRKILIQNQTDDGINFSAIREIKILQELKHDNVVNLLDIFAHKSNVYLVFELMQWDLQEVIEDKSIILK
|.....||||....|..|....||||||||||.|........||||..||||||||||..||||..|.|||.||||..|||..|.|||..||.||||||.
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKSIILT

PADIKSYMKMLLQGIEACHRNWVLHRDLKPNNLLMSINGDLKLADFGLARQYGSPNKVFSPQAVTIFYRAPELLFGAKSYGPSVDIWSIGCIFAELMLRT
||.||.||.|.|||.|.|||||.||||||||||||..||.||.|||||||.|||||.....|.||..||||||||||..||..||.||.||||||||||.
PAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELMLRV

PYLPGTGEIDQLRKICSALGTPNESNWPGVTCLPNYIKFTDHPA---TPFKQLFTAASDEAIDLISKMLLFNPSNRISAADALNHPYF
|||||...||||..|...||||.|..||...|...||||.|.|.   ||....||||||...||...|...||..|......|..|||
PYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYIKFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase Cdk7.AA CDK 4-288 43 1.8e-163 527.03 In-house 1-284 (284) Show / Hide 
Range on Protein: 4-288
Range on HMM: 1-284/284
Sequence Identity: 43% (138 aa)

YNIEALIGEGTYGVVSRATVKATG-----QIVAIKKIRKILI-QNQTDDGINFSAIREIKILQELKHDNVVNLLDIFAHK-----------SNVYLVFEL
| . . ||||||||| .|  | ||     ||||.||||     ... ..|....|||||..|.|| |.|.|.|.|.. .|           ...|.||| 
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

MQWDLQEVIEDKSIILKPADIKSYMKMLLQGIEACHRNWVLHRDLKPNNLLMSINGD-----LKLADFGLARQYGS------PNKVFSPQAVTIFYRAPE
| .|| ....          ||.||..||.|.. ||.||..||||||.|.|.. ||      ||.||||||| .|.      ||...... ||  |||||
MDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPE

LLFGAKSYG--PSVDIWSIGCIFAELML---RTPYLPGTGEIDQLRKICSALGTPNESNWPGVTCLPNYIKFTDHPATPFKQLFTAASDEAIDLISKMLL
||.|.| |.  ...|.||.||||||...   | | .||. ||||| ||.  .|||.|.|||||| ||.|                       ||..||| 
LLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-----------------------DLLNKMLC

FNPSNRISAADALNHPYF
..|..|||| .||.||||
YDPKKRISAEQALQHPYF
Kinase Cdk7.AA CMGC 4-288 26 2.2e-139 461.18 In-house 1-513 (513) Show / Hide 
Range on Protein: 4-288
Range on HMM: 1-513/513
Sequence Identity: 26% (138 aa)

YNIEALIGEGTYGVVSRATV--------------KATGQIVAIKKIR--KILIQNQ---TDDGINFSAIREIKILQELK-----------------HDNV
| |   ||||||||| ...               . |..|||||||.  .  .| .     ||....|.||||||..|.                 | |.
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VNLLDIFAHKS-----------------NVYLVFELMQWDLQEVIEDKS--------IILKPAD------------IKSYM------KMLLQGIE--ACH
|.|.||| ||                  ..|||||.|..|| ..|....        . |..              ||..|      ...|.|..   ||
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

RNW--VLHRDLKPNNLLMSINGDL--------------------KLADFGLARQYGSP---------------------NKVFSPQAVTIFYRAPELLFG
..|  ..|||||| |.|.. |..|                    |..||||||.|...                     |. .... || .|||||.|.|
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

A---------KSYGPSVDIWSIGCIFAELMLR--------TPYLP-----------GTGEIDQLRKICSALGTPN---------------ESNWPGVTCL
.         . |....|.||.||||||....         |  |           |. .|||| ||.  ||||.               | .||....|
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL

PNYIK---------------------------FTDHPATPFKQLFTA-----------------------------------ASDEAIDLISKMLLFNPS
|.|.|                           |  .|  |.|.||                                     ....||||..||| ..|.
PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD

NRISAADALNHPYF
.||.|..||.||||
KRITAEQALQHPYF
Kinase Cdk7.AA CDC2 4-288 44 1e-125 388.52 In-house 1-301 (301) Show / Hide 
Range on Protein: 4-288
Range on HMM: 1-301/301
Sequence Identity: 44% (135 aa)

YNIEALIGEGTYGVVSRATVKATGQIVAIKKIRKILIQNQTDDGINFSAIREIKILQELK-HDNVVNLLDIFAHKSNVYLVFELMQWDLQEVIE-DKSI-
|     ||||||||| ..  . |.||||.||||  | |.. .||.  .||||| .|.||| |.|.| | |..   ...|.||| .  || .  .  ..  
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIR--LEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKN

-ILKPADIKSYMKMLLQGIEACHRNWVLHRDLKPNNLLMSINGDLKLADFGLARQYGSPNKVFSPQ--AVTIFYRAPELLFGAKSYGPSVDIWSIGCIFA
  . |. .||||. .|||.. ||.. ..|||||| |.| . .|..|.|||||||  | | ..  ..   ||  |||||.|.|.| |  .||.||||||||
KHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFA

EL---MLRTPYLPGTGEIDQLRKICSALGTPNESNWPGVTCLPNYI-KFTDHPATPFKQLFTA---------ASDEAIDLISKMLLFNPSNRISAADALN
|.   . . |  .|  ||||| ||   ||||||..||||| || |  .|   ... .....           . .|.|||...||  .|..|||| .||.
EMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQ

HPYF
||||
HPYF
Kinase Cdk7.AA CDK5 4-288 44 3.4e-117 371.97 In-house 1-287 (287) Show / Hide 
Range on Protein: 4-288
Range on HMM: 1-287/287
Sequence Identity: 44% (130 aa)

YNIEALIGEGTYGVVSRATVKATGQIVAIKKIRKILIQNQTDDGINFSAIREIKILQELKHDNVVNLLDIFAHKSNVYLVFELMQWDLQEVIEDKSIILK
|.    |||||||.| .|  | |. |||.|..|     .. | |.  .||||| .|.|||| |.| | |.        |||| .  ||   ...    . 
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVR----LDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEMD

PADIKSYMKMLLQGIEACHRNWVLHRDLKPNNLLMSINGDLKLADFGLARQYGSPNKVFSPQAVTIFYRAPELLFGAKSYGPSVDIWSIGCIFAELM-LR
.. |||.|  ||.|.. || . |||||||| ||| . || |||||||||| .| | . .|   ||  ||.|  |.|.| |  |.|.||.||||||..   
MHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAG

TPYLPGTGEIDQLRKICSALGTPNESNWPGVTCLPNYI----KFTDHPATP-FKQLFTAASDEAIDLISKMLLFNPSNRISAADALNHPYF
 |  ||... ||| .|   .|||.|..||..| ||.|     ..  .||.. ..|.    . .  || .||| .||  ||||..||.||||
RPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase Cdk7.AA PITSLRE 4-288 43 3.2e-109 369.16 In-house 1-295 (295) Show / Hide 
Range on Protein: 4-288
Range on HMM: 1-295/295
Sequence Identity: 43% (129 aa)

YNIEALIGEGTYGVVSRATVKATGQIVAIKKIRKILIQ-NQTDDGINFSAIREIK-ILQELKHDNVVNLLDIF--AHKSNVYLVFELMQWDLQEVIEDKS
. .   |.|||||||.||  | |. |||.|..    .   .  .|.   ..|||. || .|.|.|.||.. |     .  .|.|.| .  ||  ..|  .
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLK---MERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMK

---IILKPADIKSYMKMLLQGIEACHRNWVLHRDLKPNNLLMSINGDLKLADFGLARQYGSPNKVFSPQAVTIFYRAPELLFGAKSYGPSVDIWSIGCIF
      ||  ||. |  || |.|  | ||..|||||  |||.| .| ||..|||||| |||| | ..|  ||  ||||||| |.| | . ||.||.||||
RRNQPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIF

AELMLRTPYLPGTGEIDQLRKICSALGTPNESNWPGVTCLPNYIKFT---DHPATPFKQLFT---AASDEAIDLISKMLLFNPSNRISAADALNHPYF
||...  | ..| .||||. .|  ..|||.|. |||.| ||.  ...   ..|    ...|      || . ||  .|| .|| |||.| ||| ||.|
AEFITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKHPWF
Kinase Cdk7.AA Pkinase 4-288 33 1.9e-99 341.46 Pfam 1-293 (293) Show / Hide 
Range on Protein: 4-288
Range on HMM: 1-293/293
Sequence Identity: 33% (101 aa)

YNIEALIGEGTYGVVSRATVKATGQIVAIKKIRKILIQNQTDDG---INFSAIREIKILQELKHDNVVNLLDIFAHKSNVYLVFELMQW-----DLQEVI
| |.  ||.|..|.| ... | ||.|||.|.|.|  .  . |     .     .||.|...|.|.|.| |.|.|  |...|.|.|...      || ..|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-----SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

E-DKSIIL--KPADIKSYMKMLLQGIEACHRNWVLHRDLKPNNLLMSINGDL----KLADFGLARQY-GSPNKVFSPQAVTIFYRAPELLFGAKSYGPSV
. ...  .   . ..|.||. .|.|.| ||.....|||||| |.|.. ||..    |..|||||.|.   .|  ..  ..|..|.|||.. |.. |||.|
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DIWSIGCIFAELMLRTPYLPGT----GEIDQLRKICSALGTPNESNWPGVTCLPNYIKFTDHPATPFKQLFTAASDEAIDLISKMLLFNPSNRISAADAL
|.||.|||..|.... |  ||     . .||. .||  .|.|....||   . ...  |.. ... .. . ...|.|..|.|...| ..|. |..|...|
DMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-WHF-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQIL

NHPYF
.||.|
QHPWF
Kinase Cdk7.AA S_TKc 4-288 28 2.8e-99 337.04 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-288
Range on HMM: 1-231/231
Sequence Identity: 28% (86 aa)

YNIEALIGEGTYGVVSRATVKATGQIVAIKKIRKILIQNQTDDGINFSAIREIKILQELKHDNVVNLLDIFAHKSNVYLVFELMQW---DLQEVIEDKSI
| |  .||.|..|.| ... | ||.|||||.|.              ...|||.||.. .|.|.|.|.|.| . ...|.|.|..     || ..|...  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

I-----LKPADIKSYMKMLLQGIEACHRNWVLHRDLKPNNLLMSINGDLKLADFGLARQYGSPNKVFSPQAVTIFYRAPELLFGAKSYGP-SVDIWSIGC
      . . ....||. .....| ||.....|||||| |.|..    .|..|||||||.       . . .| .|.|||.|    .||. ..|.||.||
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGC

IFAELML-RTPYLPGTGEIDQLRKICSALGTPNESNWPGVTCLPNYIKFTDHPATPFKQLFTAASDEAIDLISKMLLFNPSNRISAADALN-------HP
|..|..  ..|.     ..... |..                                      |.||.|.|.|.| ..|..|..| .||.       ||
ILYEMLCGYPPFP----QMQMMFKKIG-------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHP

YF
.|
WF
Kinase Cdk7.AA CCRK 4-288 45 2.3e-94 319.81 In-house 1-285 (285) Show / Hide 
Range on Protein: 4-288
Range on HMM: 1-285/285
Sequence Identity: 45% (131 aa)

YNIEALIGEGTYGVVSRATVKATGQIVAIKKIRKILIQNQTDDGINFSAIREIKILQELKHDN-VVNLLDIFAHKSNVYLVFELMQWDLQEVIEDKSIIL
| |   ||||  |.| .|    || |||.||.       . ||||   |.|||| |||.  .  || | |.| | .   |||| |  || ||. .    |
YCILDRIGEGAHGIVFKAKHVETGEIVALKKV----ALRRLDDGIPNQALREIKALQEIEDNQYVVQLKDVFPHGTGFVLVFEFMLSDLAEVVRHAQRPL

KPADIKSYMKMLLQGIEACHRNWVLHRDLKPNNLLMSINGDLKLADFGLARQYGSPN-KVFSPQAVTIFYRAPELLFGAKSYGPSVDIWSIGCIFAELML
 .| .||||.|||.|.  || | ..|||||| |||.|  | ||.||||||| .   . . .. |  | .|||||||.||. |   ||.|..|||. ||. 
AEAQVKSYMQMLLKGVAHCHENNIMHRDLKPANLLISESGHLKIADFGLARVFSNDEGRQYTHQVATRWYRAPELLYGARQYDQGVDLWAVGCIMGELLN

RTPYLPGTGEIDQLRKICSALGTPNESNWPGVTCLPNY--IKFTDHPATPFKQLFTAASDEAIDLISKMLLFNPSNRISAADALNHPYF
  |  ||  .|.||  .   ||||..  ||... || |  | | ..|  |  |.   || .|.||. . |.. |  ||.|..|| |.||
NSPIFPGENDIEQLCCVLRILGTPTPKVWPEMKDLPDYNKISFKEQPPMPLEQVVPDASPQALDLLKQFLVYPPRQRIAASQALLHQYF
Kinase Cdk7.AA CRK7 4-288 34 8.2e-87 294.71 In-house 1-343 (343) Show / Hide 
Range on Protein: 4-288
Range on HMM: 1-343/343
Sequence Identity: 34% (120 aa)

YNIEALIGEGTYGVVSRATVKATGQIVAIKKIRKILIQNQ--TDDGINFSAIREIKILQELKHDNVVNLLDIFAHK----------SNVYLVFELMQWDL
| . . ||||||| |  |  | ||..|| ||.|    .|     .|    ||||||||..|.|.|.||| .|   |           ..|.||| |  ||
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVR---MDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDL

QEVIEDKSII-LKPADIKSYMKMLLQGIEACHRNWVLHRDLKPNNLLMSINGDLKLADFGLARQYGSPN--KVFSPQAVTIFYRAPELLFGAKSY-----
    | | .    .  .|..|| || |.. ||.. .||||.|  |.||  .| .|.||||||| | | .  . .    .|  ||.|||| |.. |     
MGLLESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHI

---------------------------------GPSVDIWSIGCIFAELMLRTPYLPGTGEIDQLRKICSALGTPNESNWPGVTCLPNYIKFTDHP--AT
                                 ||..|.|| |||..||. ..| ..|  |..|| ||    |.||  ||| |. || .  .       .
LKELIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTMKPKRQYNR

PFKQLFT------AASDEAIDLISKMLLFNPSNRISAADALNHPYF
     |         . |. ||  |||  .|. |..| ..|.|..|
RLREEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase Cdk7.AA PFTAIRE 4-288 41 9.6e-83 281.2 In-house 2-287 (287) Show / Hide 
Range on Protein: 4-288
Range on HMM: 2-287/287
Sequence Identity: 41% (120 aa)

YNIEALIGEGTYGVVSRATVKATGQIVAIKKIRKILIQNQTDDGINFSAIREIKILQELKHDNVVNLLDIFAHKSNVYLVFELMQWDLQEVIEDKSIILK
 ..| | |||.|  | ..  . ..|.|| | ||  |   | . |  | ||||   |..||| |.| | ||   |    .||| .. ||   ..     ..
EKLEKL-GEGSYATVYKGISCINQQFVALKEIR--L---QQEEGTPFTAIREASLLKNLKHANIVCLHDIIHTKETLTFVFEYVHTDLCQYMDKHPGGMH

PADIKSYMKMLLQGIEACHRNWVLHRDLKPNNLLMSINGDLKLADFGLARQYGSPNKVFSPQAVTIFYRAPELLFGAKSYGPSVDIWSIGCIFAELMLRT
|  .. ..  || |   ||.  |||||||| |||.|  | ||||||||||    | . .|   ||  || |  | |.  |  ..|.| .|||| |.|   
PNNVRLFLFQLLRGLSYCHQRRVLHRDLKPQNLLISHCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMMWGQ

PYLPGT-GEIDQLRKICSALGTPNESNWPGVTCLPNY--IKFT--DHPATPFKQLFTAAS--DEAIDLISKMLLFNPSNRISAADALNHPYF
|  ||     ||| ||   ||||.|  ||||. ||||   .|.   .   . .. .   .   .| ||..|||  .| .|.||..|. ||||
PAFPGMKDITDQLEKIFKVLGTPTEDTWPGVCHLPNYKPHWFRGRFYKPKKLCHQWPRIYYIPHAEDLMMKMLQCEPRDRVSAQEAMQHPYF
Kinase Cdk7.AA MAPK 126-288 38 1.4e-65 224.16 In-house 138-328 (328) Show / Hide 
Range on Protein: 126-288
Range on HMM: 138-328/328
Sequence Identity: 38% (73 aa)

VLHRDLKPNNLLMSINGDLKLADFGLARQYGS-PNKVF-------------SPQAVTIFYRAPELLFG--AKSYGPSVDIWSIGCIFAELML-RTPYLPG
|.|||||| |.|.  |.|||..||||||.  .  ..               ..  .| .|||||....  .. |  .||.||.||||||..  |.| .||
VIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPG

TGEIDQLRKICSALGTPNESNWPGVT-C-LP-NYIK----FTDHPATPFKQLFTA----ASDEAIDLISKMLLFNPSNRISAADALNHPYF
.  |||. .| . |||| |  .  .. .  . |||.    .. .|. |....|      |...||||..||| |.|. ||....||.||||
KDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase Cdk7.AA MAPK 4-96 33 4.3e-29 97.6 In-house 1-107 (328) Show / Hide 
Range on Protein: 4-96
Range on HMM: 1-107/328
Sequence Identity: 33% (39 aa)

YNIEALIGEGTYGVVSRATVKA------TGQIVAIKKIR-----KILIQNQTDDGINFSAIREIKILQEL-KHDNVVNLLDIFAH------KS-----NV
|.|   ||.| ||||  |. |       .|..||||||      ... .          ..||||.|... .|.|...|||||        .|      .
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCK---------RTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDI

YLVFELMQWDLQEVIE
|.|.|||..||. .|.
YIVMELMETDLHQIIK
Kinase Cdk7.AA TyrKc 4-288 20 1.9e-13 -5.08 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-288
Range on HMM: 1-280/280
Sequence Identity: 20% (65 aa)

YNIEALIGEGTYGVVSRATVKATGQIVAIKKIRKILIQNQTDDGINFSAIREIKILQEL--KHDNVVNLLDIFAHK-------SNVYLVFELMQW-DLQE
   .  .||| .|.| ..| |   . ||.|....               .||..|. .|  .|.|.|.|. .  ..         ...|.|.| . ||..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

VIEDKSIILKPADIKSYMKMLLQGIEACHRNWVLHRDLKPNNLLMSINGDLKLADFGLARQYGSP------NKVFSP----QA---VTIFYRAPELLFGA
 . ..   |...|  |..    .| |  |.. . ||||   | | . |.  | .||||.|  ..        .. ..    ..   . |   ||| ..  
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

KSYGPSVDIWSIGCIFAELMLR--TPYLP------GTGEIDQLRKICSALGTPNE----SNWPGVTCLPNYIKFTDHPATPFKQLFTAASDEAIDLISKM
| . .  |.|| |    |.. .  .||           |. .. |    .  | .    |                         |  ..||  ..... 
K-FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-------------------------FVCCPDEMYQIMKQC

LLFNPSNRISAADALNHPYF
  ..|..| . ..   | .|
WHEDPEDRPTFSEI--HECF
Kinase Cdk7.AA Pkinase_Tyr 4-88 26 3e-11 38.74 Pfam 1-90 (270) Show / Hide 
Range on Protein: 4-88
Range on HMM: 1-90/270
Sequence Identity: 26% (25 aa)

YNIEALIGEGTYGVVSRATVK----ATGQIVAIKKIRKILIQNQTDDGINFSAIREIKILQEL-KHDNVVNLLDIFA-HKSN--VYLVFELMQ
  .   .||| .|.| ..| |     |.. ||.|...    . |    .  . .||.||. .| .|.|.|.|. .   ..    .|.|.|.|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQN---CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMP
Kinase Cdk7.AA Pkinase_Tyr 145-153 77 7.864077 0.05 Pfam 151-159 (270) Show / Hide 
Range on Protein: 145-153
Range on HMM: 151-159/270
Sequence Identity: 77% (7 aa)

KLADFGLAR
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KICDFGLAR