Gene CK2 (Slime mold)

CK2

Species: Slime mold
Alias: DDB0185025, DdisK055, casK, CK2
External Links: DictyBase Link ,
Annotation:

Classification

Group: CMGC
Family: CK2

Sequence

Name Sequence Type Origin Length Description Download
CK2.AA Protein None 337 None Fasta, JSON
CK2.kin_dom Protein Kinase Domain None 286 None Fasta, JSON

Protein domain

Protein domains of CK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CK2.AA CK2 47-332 76 2.9e-233 704.93 In-house 1-288 (288) Show / Hide 
Range on Protein: 47-332
Range on HMM: 1-288/288
Sequence Identity: 76% (221 aa)

YEIIRKIGRGKYSEVFEGANIKNNEKC--VIKVLKPVKKKKIKREIKILQNLCGGPNIITLYDVVRDPQSKTPSLIFEYINNTDFKHLSPTLTDFDVRYY
||.|||||||||||||||.||||||||  |||.||||||||||||||||.||.||||||.|||.|.||.||.|.|.|||.|||||..|..||||.|.|||
YEVIRKIGRGKYSEVFEGINIKNNEKCKIVIKILKPVKKKKIKREIKILENLNGGPNIIKLYDIVKDPYSKVPALVFEYVNNTDFRQLYQTLTDYDIRYY

IRELLHALDFCHSNGIMHRDVKPSNVMIDHQKRKLYLIDWGLAEFYHPNQDYNVRVASRPYKGPELLVDMEDYDYSLDMWSLGCMFAGMLFQKDPFFHGH
..|||.|||.|||.|||||||||.|.||||.||||.||||||||||||.|||||||||| |||||||||...|||||||||||||||.|.|.|.||||||
MFELLKALDYCHSMGIMHRDVKPHNIMIDHEKRKLRLIDWGLAEFYHPGQDYNVRVASRYYKGPELLVDYQYYDYSLDMWSLGCMFASMIFKKEPFFHGH

DNIDQLVKIVKILGTEEFYAYLDKYGIVVDHTILSIIGKHPKKPWSRFITKENQHLAVPEAIDFLEKLLRYDPAERLTTREAMEHPYF
||.||||||||.||||..|.||||||| .|... .|...| ||||.|||..||.|||.|||||||.|.||||..||.|..||||||||
DNYDQLVKIVKVLGTEDLYKYLDKYGIHLDPQFHDIMQQHKKKPWERFIHQENKHLAHPEAIDFLDKMLRYDHQERITAKEAMEHPYF
Kinase CK2.AA CMGC 47-332 21 1.4e-106 351.38 In-house 1-513 (513) Show / Hide 
Range on Protein: 47-332
Range on HMM: 1-513/513
Sequence Identity: 21% (112 aa)

YEIIRKIGRGKYSEVFEGAN--------------IKNNEKCVIKVLKPVKKKKIK---------------REIKILQNLC----------------GGPN
||||.|||.| |..|... .              ...||.. || .| .. ...                ||||||..|                   .|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IITLYDVVRDPQSKTP---------------SLIFEYINNTDFKHLSP-----------TLTDFD------------VRYYI------RELLHALD--FC
|..|||......|...                |.|||. .. .. .              |..              ..|..      . .| .|.  .|
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSNG--IMHRDVKPSNVMIDHQKRK-------------------LYLIDWGLAEFYHPNQD----------------------YNVRVASRPYKGPELLV
||..  |.||| ||.|..|.|...                    | ..|.||| .|||..|                      |  .|..| |. ||.|.
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

DMEDYD---------YSLDMWSLGCMFAGM-------LFQKDPFFHGHDN-----------IDQLVKIVKILG------------------TEEFYAYLD
 ...|.         .. ||||.||.|| |       .|...|.|.||..           |||| ||.|.||                  .||.. ...
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

KYGIVVDHT---------ILSI-----------IGKHPKKPWSRFITKENQ------------------------------HLAVPEAIDFLEKLLRYDP
...   . .         ..|.            ...|.|||.... . .                               ... |.|||.|.|.|.|||
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

AERLTTREAMEHPYF
..|.|  .|..||||
DKRITAEQALQHPYF
Kinase CK2.AA Pkinase 47-332 26 2.4e-83 287.97 Pfam 1-293 (293) Show / Hide 
Range on Protein: 47-332
Range on HMM: 1-293/293
Sequence Identity: 26% (82 aa)

YEIIRKIGRGKYSEVFEGANIKNNEKCVIKVLKPVKKKKIKR-------EIKILQNLCGGPNIITLYDVVRDPQSKTPSLIFEYINNT----DFK-----
|.|.||||.| ...|... ....... ..|..| ...|. |.       ||.|...| . |||..|||...|  .. . ...|| ...    | .     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

HLSPTL--TDFDVRYYIRELLHALDFCHSNGIMHRDVKPSNVMIDHQKRK---LYLIDWGLAEF--YHPNQDYNVRVASRPYKGPELLVDMEDYDYSLDM
. . ..  .. ... |....| .|..|||.||.|||.||.|..||..      . ..|.|||..  | .|. ..... ...|  ||.. . ..|... ||
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSLGCMFAGMLFQKDPFFHG---HDNIDQLVKIVKILGTEEFYAYLDKYGIVVDHTILSIIGKHPKKPWSRFITKENQHLAVPEAIDFLEKLLRYDPAER
||.||... ||. . || .    .. .||...|..|.|..  . .  .. |  ..  ...   |       | .... |.. .|..||....|..||..|
WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF--FRH-W-H-------F-HWTF-HNWSEECKDFIKWCLCKDPKKR

LTTREAMEHPYF
.| .....||.|
PTAEQILQHPWF
Kinase CK2.AA S_TKc 47-332 27 3e-77 263.88 SMART 1-231 (231) Show / Hide 
Range on Protein: 47-332
Range on HMM: 1-231/231
Sequence Identity: 27% (83 aa)

YEIIRKIGRGKYSEVFEGANIKNNEKCVIKVLKPVKKKKIKREIKILQNLCGGPNIITLYDVVRDPQSKTPSLIFEYINN--TDFKHLSPT---------
|||.||||.| ...|. . ..| .... ||..|    ..|.|||.||..  . |||..|||| .|   .   ...||...   | ...            
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LTDFDVRYYIRELLHALDFCHSNGIMHRDVKPSNVMIDHQKRKLYLIDWGLAEFYHPNQDYNVRVASRPYKGPELLVDMEDYDY-SLDMWSLGCMFAGML
..  ..|.|..... ||..|||.||.|||.||.|...|.    . ..| ||| ..      .  . .. |  ||.|     |.. . |.||.||... ||
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

FQKDPFFHGHDNIDQLVKIVKILGTEEFYAYLDKYGIVVDHTILSIIGKHPKKPWSRFITKENQHLAVPEAIDFLEKLLRYDPAERLTTREAME------
  . ||        |. .. |..|                                            |||.||..|.|..||..|.|  ||..      
CGYPPFP-------QMQMMFKKIG-------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIK

-HPYF
 ||.|
CHPWF
Kinase CK2.AA CDK 47-259 30 9.6e-58 183.25 In-house 1-243 (284) Show / Hide 
Range on Protein: 47-259
Range on HMM: 1-243/284
Sequence Identity: 30% (78 aa)

YEIIRKIGRGKYSEVFEGANIKNN-----EKCVIKVLK-PV-----KKKKIK----REIKILQNLCGGPNIITLYDVVRDPQS---------KTPSLIFE
||.. |||.| | .|. . . ...     . . .| ..        .|  .     |||..|..|   |||..|.||. . ..         .. ...||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

YINNT-----DFKHLSPTLTDFDVRYYIRELLHALDFCHSNGIMHRDVKPSNVMIDHQKR----KLYLIDWGLAEFYH-------PNQDYNVRVASRPYK
|.        |            .. |.. || .|..||||.||||| ||.| .|...      .| . | |||  ..       ||. |  .|  . | 
YMDHDLKKYMD------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYR

GPELLVDMEDYD--YSLDMWSLGCMFAGMLF--QKDPFFHGHDNIDQLVKIVKILGT
 ||||   ..|.   . ||||.|| || |.   .. |.|.|   |||| || .|.||
APELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGT
Kinase CK2.AA CAMK 52-229 19 1.1e-50 161.12 In-house 1-323 (425) Show / Hide 
Range on Protein: 52-229
Range on HMM: 1-323/425
Sequence Identity: 19% (62 aa)

KIGRGKYSEVFEGANIKNN------------EKCVIKVLK-------------------------------PVKKKKIKREIKILQNLCG------GPNI
..||| ...|... .....            .|. ||...                               |...|...|||.|...| |       |||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

ITLYDVVRDPQSK-------TPS-----------LIF---EYINNT----D-FKHLS-----------------PTLTDFDVRYYIRELLHALDFCHSNG
| ||.|  ||.         | |           ...   ||. .     | | ..                    .|  ..|.|.| .. |...|||..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IMHRDVKPSNVMIDHQK----------------RKLYLIDWGLAEFYHP------------------------NQDYNVRVASRPYKG-PELLVD-----
|.||| || |...|. .                 .. .||.|.| .. |                        .| .. .. . .|   ||.|       
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------MEDYDYSLDMWSLGCM
         . |... ||||.|..
MQNATDEEKPYYGPKCDMWSCGVI
Kinase CK2.AA Ciliate-E2 47-332 17 1.6e-48 164.71 In-house 1-365 (365) Show / Hide 
Range on Protein: 47-332
Range on HMM: 1-365/365
Sequence Identity: 17% (76 aa)

YEIIRKIGRGKYSEVFEGANIKNNE------------------KCV-----IKVLKPVKKKKIKREIKILQ---------N------LCGGPNIITLYDV
|..|.|||.| .. |... ..|...                  |.      .|..|. ... ||.||.|..         |      .   |||| .|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VRDPQSKTPSLIFEYINNTDFKH---------------LSPTLTDFDVRYYIRELLH---------------ALDFCHSNG-IMHRDVKPSNVMIDHQKR
  . . ..  |..||..  | ..                   .|.. ..|.....|                || ..||.. |.||| ||.|...     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

KLYLIDWGLAEFYHPNQD--------------------------------YNVRVASRPYKGPELLVDMED--------YDYSLDMWSLGCMFAGMLFQK
 . .||.||. .|.....                                .|  . . .|. || |   ..        |||. |.||||...  ||| |
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

DPFFHGHDNIDQLVKIVKILGTEEFYAYLDKYGIVVDHTILSIIGKHPKKPWSRFITKENQHLAVP-----------------------EAIDFLEK---
 ||                                                   .. .... .  |                       |..|.. |   
PPF---------------------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGK

-LLRYDPAERLT-TREAMEHPYF
 .| .|| .|.|   ....||.|
RMLQKDPEKRITGWEQILNHPWF
Kinase CK2.AA CAMKL 47-227 28 3.5e-43 135.57 In-house 1-223 (297) Show / Hide 
Range on Protein: 47-227
Range on HMM: 1-223/297
Sequence Identity: 28% (63 aa)

YEIIRKIGRGKYSEVFEGANIKN-NEKCVIKVLKPVKKKK------------------IKREIKILQNLC--GGPNIITLYDVVRDPQS----KTPSLIF
|.|.. .|.| ...|  . .|.. .||  ||...  |...                  |.|||.|.. |   . |||| ||.|. .|.     |   |. 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYINNTD---FKHLSPT------LTDFDVRYYIRELLHALDFCHSNGIMHRDVKPSNVMIDHQKR-KLYLIDWGLAEFYHP-----NQDYNVRVASRPYK
||. . .   | ..         ..  . | | | ...|...|||.|| ||| || |...|.... .. .|| |.. .| |     .|  . .  | || 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

GPELLVD-MEDYD-YSLDMWSLG
 ||.. .  ..|| .  |.||.|
APEIFQGNNKPYDGPKVDIWSCG
Kinase CK2.AA ERK7 47-332 28 6.2e-43 144.5 In-house 1-292 (292) Show / Hide 
Range on Protein: 47-332
Range on HMM: 1-292/292
Sequence Identity: 28% (87 aa)

YEIIRKIGRGKYSEVFEGANIKNNEKCVIKVL-----KPVKKKKIKREIKILQNLCGGPNIITLYDVVRDPQSKTPSLIFEYINNTDFKHLSP---TLTD
|||....|.| |  |      .  .   .|        ..   .  ||| .||.. . |||| |..|.|    .   |.||.  .||          | |
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADNDRDIYLVFEFM-ETDLHAVIRKGNILKD

FDVRYYIRELLHALDFCHSNGIMHRDVKPSNVMIDHQKRKLYLIDWGLA-------EFYHPNQDYNVRVASRPYKGPELLVDMEDYDYSLDMWSLGCMFA
  ..| .  || |. . ||  ..|||.||||...| . . . . | |||       |.   |..    || | |  || |.  . |    ||||.||  .
IHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECM-VKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILG

GMLFQKDPFFHGHDNIDQLVKIVKILGTEEFYAYLDKYGIVVDHTILSIIGKHPKKPWSRFITKENQHLAVPEAIDFLEKLLRYDPAERLTTREAMEHPY
 || .| | | |   ..|. ||.....    .. .   |  .  ..|. ......|. . ....     . ..||| | .|| . | .|||  .|..|||
EMLRGK-PMFPGTSTMNQIEKILETIPKPT-QEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMPQ-----CCDDAIDLLKRLLVFNPKKRLTAEQALQHPY

F
 
V
Kinase CK2.AA CDC2 47-259 33 1.1e-40 122.42 In-house 1-227 (301) Show / Hide 
Range on Protein: 47-259
Range on HMM: 1-227/301
Sequence Identity: 33% (79 aa)

YEIIRKIGRGKYSEVFEGANIKNNEKCVIKVLKPVKKKKIK--------REIKILQNLCGGPNIITLYDVVRDPQSKTPSLIFEYINNTDFKHLSP----
|. |.||| | | .|. . . . |. ...|  . ..             ||| .|..|   |||..| ||.     .   ..|||. . | | .      
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIR-LEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYL-DMDLKKYMDMSIP

---TLTDFDVRYYIRELLHALDFCHSNGIMHRDVKPSNVMIDHQKRKLYLIDWGLA-EFYHPNQDYN--VRVASRPYKGPELLVDMEDYDYSLDMWSLGC
    ..   |. |.  .| ...|||...||||| ||.|  || . . . . | |||  |  |   |     |  . |  ||.|   ..|. . ||||.||
KNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGN-IKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGC

MFAGM-LF-QKDPFFHGHDNIDQLVKIVKILGT
 || | .  .| |.|||   |||| || .||||
IFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGT
Kinase CK2.AA RCK 47-259 31 2.2e-37 115.98 In-house 1-232 (298) Show / Hide 
Range on Protein: 47-259
Range on HMM: 1-232/298
Sequence Identity: 31% (75 aa)

YEIIRKIGRGKYSEVFEGANIKNNEKCVIKVLKPVKKKKIK-----REIKILQNLCGGPNIITLYDVVRDPQSKTPSLIFEYINN------TDFKHLSPT
| ||...|.| |..|... |....|.  || .|  | ....     |||| |  |   |||| |..|.||  . . ...|||  .       |||  . .
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMK-QKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMDMNLYQMMKDFKE-RRK

-LTDFD--VRYYIRELLHALDFCHSNGIMHRDVKPSNVMIDHQ--------KRKLYLIDWGLA-EFY--HPNQDYNVRVASRPYKGPELLVDMEDYDYSL
 |. .   .. ..  .| .|...|..|..|||.|| | |.  .           . ..| ||. |..  .|. ||   | .| |  ||.|     |.. .
YLPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPPYTDY---VSTRWYRAPECLLRCTYYNSPM

DMWSLGCMFAGMLFQKDPFFHGHDNIDQLVKIVKILGT
|.|..|| ..  |  . | | | . |||. ||.|..||
DIWAVGCIMYE-LYMLRPLFPGSSEIDQIFKICKVMGT
Kinase CK2.AA MAPK 200-332 41 5.8e-33 111.2 In-house 192-328 (328) Show / Hide 
Range on Protein: 200-332
Range on HMM: 192-328/328
Sequence Identity: 41% (59 aa)

VASRPYKGPELLVD--MEDYDYSLDMWSLGCMFAGMLFQKDPFFHGHDNIDQLVKIVKILGT--EEFYAYLDKYGIVVDHTILSIIG-----KHPKKPWS
|| | |  ||..    . .|. . ||||.|| || || .  |.| |.| |||. .|...|||  |||. .. .     .|    | .     |.|||||.
VATRWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICM----SEHARNYIQSLGNLPKYPKKPWE

RFITKENQHLAVPEAIDFLEKLLRYDPAERLTTREAMEHPYF
  . ..|  .| |.|||.|||.|  || .|.|  ||..||||
KMFPNANF-NANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase CK2.AA CDC2 293-332 47 6.4e-15 41.78 In-house 262-301 (301) Show / Hide 
Range on Protein: 293-332
Range on HMM: 262-301/301
Sequence Identity: 47% (19 aa)

ITKENQHLAVPEAIDFLEKLLRYDPAERLTTREAMEHPYF
..| ||  . ||.|| |...|.|||. |.. .||..||||
QKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase CK2.AA CDK 307-332 50 5.9e-13 37.63 In-house 259-284 (284) Show / Hide 
Range on Protein: 307-332
Range on HMM: 259-284/284
Sequence Identity: 50% (13 aa)

DFLEKLLRYDPAERLTTREAMEHPYF
|.|.|.| |||. |..  .|..||||
DLLNKMLCYDPKKRISAEQALQHPYF
Kinase CK2.AA RCK 303-332 43 2.7e-12 35.0 In-house 269-298 (298) Show / Hide 
Range on Protein: 303-332
Range on HMM: 269-298/298
Sequence Identity: 43% (13 aa)

PEAIDFLEKLLRYDPAERLTTREAMEHPYF
...|. .||.|..|| .| |  .| .||||
QDCIELMEKMLQWDPQKRITAQQALQHPYF
Kinase CK2.AA CAMK 303-332 33 2.9e-11 31.84 In-house 396-425 (425) Show / Hide 
Range on Protein: 303-332
Range on HMM: 396-425/425
Sequence Identity: 33% (10 aa)

PEAIDFLEKLLRYDPAERLTTREAMEHPYF
.|..|.. |.|..|| .|.|  ....|| .
QECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CK2.AA TyrKc 47-332 16 5.2e-10 -60.8 SMART 1-280 (280) Show / Hide 
Range on Protein: 47-332
Range on HMM: 1-280/280
Sequence Identity: 16% (54 aa)

YEIIRKIGRGKYSEVFEGANIKNNEKCVIKVLKPVKKKKIKREIKILQNL-CGGPNIITLYDVVRDP-----QSKTPSLIFEYINNTDFKH----LSPTL
 . ..|.|.| . ||..|  .   ... .|.||. ... . ||..|. .|    |||. || |....      .. . ...||  . | |.      |.|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKL

TDFDVRYYIRELLHALDFCHSNGIMHRDVKPSNVMIDHQKRKLYLIDWGLAEFYHPN-------QDYNVR---VAS--RPYK--GPELLVDMEDYDYSLD
.  |  ..        .. ||... |||    |.......      | ||. . .         . | ..    .    |..   || . . . .    |
CMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK-FTTKSD

MWSLGCM------FAGMLFQKDPFFHGHDNIDQLVKIVKILGTEEFYAY----LDKYGIVVDHTILSIIGKHPKKPWSRFITKENQHLAVPEAIDFLEKL
 || | .      . ..    . .     . ..... ||  .  .  ..                              |        . .|  .  .. 
VWSFGVCMWEIFTYGQQPYPGMIQQ--MMSNQEVIEYVKQGYRMPQPPNDYPMS-------------------------F------VCCPDEMYQIMKQC

LRYDPAERLTTREAMEHPYF
 ..||..| | .|   | .|
WHEDPEDRPTFSEI--HECF
Kinase CK2.AA CAMKL 304-332 31 4.5e-08 21.7 In-house 269-297 (297) Show / Hide 
Range on Protein: 304-332
Range on HMM: 269-297/297
Sequence Identity: 31% (9 aa)

EAIDFLEKLLRYDPAERLTTREAMEHPYF
...|.. |.|  .| .| |  . |.|| .
DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase CK2.AA MAPK 47-110 29 4e-07 20.43 In-house 1-75 (328) Show / Hide 
Range on Protein: 47-110
Range on HMM: 1-75/328
Sequence Identity: 29% (22 aa)

YEIIRKIGRGKYSEVFEGANIK------NNEKCVIKVLK-----PVKKKKIKREIKILQNLCGGPNIITLYDVVR
|.|...|| | |  |.     .      ...| .|| .      |.  | . ||||.|. . . .||| |.|. .
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFT
Kinase CK2.AA Pkinase_Tyr 47-126 25 1.2e-05 19.72 Pfam 1-91 (270) Show / Hide 
Range on Protein: 47-126
Range on HMM: 1-91/270
Sequence Identity: 25% (23 aa)

YEIIRKIGRGKYSEVFEGANI----KNNEKCVIKVLKP---VK---KKKIKREIKILQNLCGGPNIITLYDVVRDPQSKT--PSLIFEYINN
 ....|.|.| . ||..|       ... .. .|.||.    .   ...  ||.||. .|.  |||. || |.  .|..   . ...||  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCT-DQGEPNQIYIVMEYMPH
Kinase CK2.AA APH 145-192 25 7.5e-05 17.43 Pfam 160-207 (248) Show / Hide 
Range on Protein: 145-192
Range on HMM: 160-207/248
Sequence Identity: 25% (13 aa)

IRELLHALDFCHSNGIMHRDVKPSNVMID--HQKRKL-YLIDWGLAEFYHP
...|. ...     ...|.|..| |||.|   .. .. ..|||. | . .|
WAWLEAHWP---PPCWCHGDFHPGNVMWDPRPDGGRVTGVIDWDDACWGDP
Kinase CK2.AA MAPK 156-173 50 0.000329 10.2 In-house 134-151 (328) Show / Hide 
Range on Protein: 156-173
Range on HMM: 134-151/328
Sequence Identity: 50% (9 aa)

HSNGIMHRDVKPSNVMID
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HSANVIHRDLKPSNILVN