Gene DDB0219953 (Slime mold)

DDB0219953

Species: Slime mold
Alias: DDB0219953, DdisK056
External Links: DictyBase Link ,
Annotation:

Classification

Group: CMGC
Family: CK2

Sequence

Name Sequence Type Origin Length Description Download
DDB0219953.AA Protein None 605 None Fasta, JSON
DDB0219953.kin_dom Protein Kinase Domain None 286 None Fasta, JSON

Protein domain

Protein domains of DDB0219953.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0219953.AA CK2 312-597 67 4.8e-213 643.38 In-house 1-288 (288) Show / Hide 
Range on Protein: 312-597
Range on HMM: 1-288/288
Sequence Identity: 67% (193 aa)

YEVIQKIGRGKYSEVFSGIDIETSDEV--VIKVLKPVQKLKIQREIKILESLNGGPNIIPLLDSVKDQSSKVCSLVFPFVNKTDIRELVYTLDDYDIRYY
||||.|||||||||||.||.|......  |||.||||.| ||.|||||||.|||||||| |.|.|||..|||..|||..||.||.|.|..||.|||||||
YEVIRKIGRGKYSEVFEGINIKNNEKCKIVIKILKPVKKKKIKREIKILENLNGGPNIIKLYDIVKDPYSKVPALVFEYVNNTDFRQLYQTLTDYDIRYY

IFELLKAIDYTHSKGIIHRDIKPLNIAIDHSKRKLSLIDWGLAEYYHPGKNYNVRVASRHYKPPELLVNMFDYDYSLDMWSLGCLFAGLILDRDPFFNGD
.||||||.||.||.||.|||.|| ||.|||.||||.||||||||.||||..||||||||.||.|||||.. .||||||||||||.||..|....|||.|.
MFELLKALDYCHSMGIMHRDVKPHNIMIDHEKRKLRLIDWGLAEFYHPGQDYNVRVASRYYKGPELLVDYQYYDYSLDMWSLGCMFASMIFKKEPFFHGH

NNNDQLLKIVKVLGTDDLFNFLDKFGLSLTDEQSSLIKPRQKSNWERFIPYENDDIAQPDAIDFLDKLLRYDPTERLTAKEAMKHPYF
.|.|||.||||||||.||...|||.|..|......... ..|..||||| .||...|.|.|||||||.||||..||.||||||.||||
DNYDQLVKIVKVLGTEDLYKYLDKYGIHLDPQFHDIMQQHKKKPWERFIHQENKHLAHPEAIDFLDKMLRYDHQERITAKEAMEHPYF
Kinase DDB0219953.AA CMGC 312-597 21 1.2e-100 331.53 In-house 1-513 (513) Show / Hide 
Range on Protein: 312-597
Range on HMM: 1-513/513
Sequence Identity: 21% (109 aa)

YEVIQKIGRGKYSEVFSGID--------------IETSDEVVIKVLKPVQKLKIQ---------------REIKILESLN----------------GGPN
||.|.|||.| |..|....|              .||  .| || .| ..  ..|               ||||||. ||                  .|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IIPLLDSVKDQSSK---------------VCSLVFPFVNKTDIRELVY-----------TLDDYD------------IRYYI------FELLKAID--YT
|. |.|....  |.                  ||| .. ..  . .              |..              |.|..      . .|....  | 
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSKG--IIHRDIKPLNIAIDHSKRK-------------------LSLIDWGLAEYYHPG----------------------KNYNVRVASRHYKPPELLV
||..  |||||.|| || |.| ..                    | ..|.||| .|||                       . |  .|..|.|..||.|.
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

NMFDYD---------YSLDMWSLGCLFAGLILD-------RDPFFNGDNN-----------NDQLLKIVKVLG------------------TDDLFNFLD
.. .|.         .. ||||.|| || ...        ..|.| |...            ||| ||.||||                  ... .|...
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

KFGLSLTDE----------QSSL----------IKPRQKSNWERFIPYEN-----------------DDIAQ-------------PDAIDFLDKLLRYDP
. .  .. .          .|.            ..... .|....|  .                  ....             |.|||.|.|.|.|||
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

TERLTAKEAMKHPYF
..|.||..|..||||
DKRITAEQALQHPYF
Kinase DDB0219953.AA Pkinase 312-597 24 4.4e-74 257.22 Pfam 1-293 (293) Show / Hide 
Range on Protein: 312-597
Range on HMM: 1-293/293
Sequence Identity: 24% (77 aa)

YEVIQKIGRGKYSEVFSGIDIETSDEVVIKVLKPVQKLKIQR-------EIKILESLNGGPNIIPLLDSVKDQSSKVCSLVFPFVNKT----DIRELVY-
|....|||.| ...|. .... |...|..|..| . . . ..       ||.|. .| . |||. |.|.. |  .. . .|.......    |  ...  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

----TL--DDYDIRYYIFELLKAIDYTHSKGIIHRDIKPLNIAIDHSKRK---LSLIDWGLAEY--YHPGKNYNVRVASRHYKPPELLVNMFDYDYSLDM
    ..  .. ... |. ..|....| ||.||||||.|| || ||.       . ..|.|||.   | ..  ..... ...| .||..    .|... ||
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSLGCLFAGLILDRDPFFNG---DNNNDQLLKIVKVLGTDDLFNFLDK------FGLSLTDEQSSLIKPRQKSNWERFIPYENDDIAQPDAIDFLDKLLR
||.||... ... | || .    || .||. .|....|..  |..  .      | ..  .                | . .. . . ....||....|.
WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H--------------F-HWTF-HNWSEECKDFIKWCLC

YDPTERLTAKEAMKHPYF
.||..|.||.....||.|
KDPKKRPTAEQILQHPWF
Kinase DDB0219953.AA S_TKc 312-597 25 2.1e-71 244.45 SMART 1-231 (231) Show / Hide 
Range on Protein: 312-597
Range on HMM: 1-231/231
Sequence Identity: 25% (78 aa)

YEVIQKIGRGKYSEVFSGIDIETSDEVVIKVLKPVQKLKIQREIKILESLNGGPNIIPLLDSVKDQSSKVCSLVFPFVNK--TDIRELVYT---------
||...|||.| ...|. .....|  .| ||..|     .|.|||.||..  . |||. |.|.  |   .   .|. ...    | ...            
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LDDYDIRYYIFELLKAIDYTHSKGIIHRDIKPLNIAIDHSKRKLSLIDWGLAEYYHPGKNYNVRVASRHYKPPELLVNMFDYDY-SLDMWSLGCLFAGLI
..  ..|.|. ....|..| ||.||||||.|| || .|.    . ..| |||  .      .  . ...| .||.|     |.. . |.||.||... ..
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

LDRDPFFNGDNNNDQLLKIVKVLGTDDLFNFLDKFGLSLTDEQSSLIKPRQKSNWERFIPYENDDIAQPDAIDFLDKLLRYDPTERLTAKEAMK------
  . | |       |. .. |..|                                            |.|.||..|.|..||..|.|| ||..      
C-GYPPFP------QMQMMFKKIG-------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIK

-HPYF
 ||.|
CHPWF
Kinase DDB0219953.AA CDK 312-597 28 1.2e-61 195.98 In-house 1-284 (284) Show / Hide 
Range on Protein: 312-597
Range on HMM: 1-284/284
Sequence Identity: 28% (93 aa)

YEVIQKIGRGKYSEVFSGIDIETS-----DEVVIKVLKPVQ------KLKIQ----REIKILESLNGGPNIIPLLDSVKDQSS---------KVCSLVFP
|| ..|||.| | .|. ..| .|      . | .| ..  .      |  .     |||..|  |   |||. |.| . . ..         .  ..||.
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

FVNKT-----DIRELVYTLDDYDIRYYIFELLKAIDYTHSKGIIHRDIKPLNIAIDHSKR----KLSLIDWGLAEYYH-------PGKNYNVRVASRHYK
..        |            |. |.. ||....| ||..|.|||.|| || |..       .| . | |||  ..       | . |  .|  . | 
YMDHDLKKYMD------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYR

PPELLVNMFDYD--YSLDMWSLGCLFAGLILD--RDPFFNGDNNNDQLLKIVKVLGT--DDLFNFLDKFGLSLTDEQSSLIKPRQKSNWERFIPYENDDI
.||||    .|.   . ||||.|| || ...|  | |.| ||.  ||| || ...||  .|    . |. .                             
APELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY----------------------------

AQPDAIDFLDKLLRYDPTERLTAKEAMKHPYF
      |.|.|.| |||. |..|..|..||||
------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase DDB0219953.AA CDC2 312-597 30 5.9e-48 145.17 In-house 1-301 (301) Show / Hide 
Range on Protein: 312-597
Range on HMM: 1-301/301
Sequence Identity: 30% (95 aa)

YEVIQKIGRGKYSEVFSGIDIETSDEVVIKVLKPVQKLKI-------QREIKILESLNGGPNIIPLLDSVKDQSSKVCSLVFPFVNKTDIRELVY-----
|. |.||| | | .|. ..| .| . |..|  .  |   .        ||| .|  |.  |||. | | ..    .   .|| ...  | ...       
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLD-MDLKKYMDMSIPK

--TLDDYDIRYYIFELLKAIDYTHSKGIIHRDIKPLNIAIDHSKR-KLSLIDWGLA-EYYHPGKNYN--VRVASRHYKPPELLVNMFDYDYSLDMWSLGC
   ..   .. |.. .|..... |...|.|||.|| || || . . |..  | |||     | ..|     |  . | .||.|    .|. . ||||.||
NKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIA--DFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGC

LFAGLILD--RDPFFNGDNNNDQLLKIVKVLGT---------DDLFNFLDKFGLSLTDEQSSLIKPRQKSNWERFIPYENDDIAQPDAIDFLDKLLRYDP
.|| . .|  . |.| ||   ||| || ..|||         ..|  .  .|.   .   |.... .||        ..   .. |..|| |...|.|||
IFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKK-------KNQ-SCLDPEGIDLLMQMLQYDP

TERLTAKEAMKHPYF
  |..||||..||||
QKRISAKEALQHPYF
Kinase DDB0219953.AA CDK-Unclassified 312-597 27 1e-44 144.92 In-house 1-324 (324) Show / Hide 
Range on Protein: 312-597
Range on HMM: 1-324/324
Sequence Identity: 27% (91 aa)

YEVIQKIGRGKYSEVFSGIDIETSDEVVIKVLKPVQ---------------KLKIQREIKILESLNGGPNIIPLLDSVKDQSSKVCS-------------
|. ..|.|.| . .|. .|| .|. .| || .   .               |.  ||||..|  .|   ||| ..| . | .   ||             
YRMQCKYGEGTFGCVCKAIDFQTQKHVAIKKIMVNNKKGNKCKHILPLLNSKITDQREISCLQNCNHM-NIIKFMDMHYDHDR--CSKNPYYDNLHPSFY

LVFPFVNKTD---IRELVYTLDDYDIRYYIFELLKAIDYTHSKGIIHRDIKPLNIAIDHSK----RKLSLIDWGLAEYYH-------------PGKNYNV
.| . .  |        .| |   .|| .   .|. | | |...|.|||||| || |..       .| ..| |.|  |              |.. | .
MVMEYMPYTWYNQLHNNRYNLSMCQIRNFMHQMLEGIAYLHCNKIMHRDIKPQNIMITNNNSTVSPMLKIADFGQACFYMNCPPNLNYQTPADPMQQYST

RVASRHYKPPELLVNMFDYDYSLDMWSLGCLFAGLILDRDPFFNGDNNNDQLLKIVKVLGTDDLFNFLDKFGLSLTDEQSSLIKPRQKSN-WERFIPYEN
 |. | |. ||||     ||.  |.||.|| .| ..  . | | | .  .|. .| |.|||  . .  |  . .. |  . . |. || . |.||  .  
QVSTRWYRAPELLFGSKCYDTGVDIWSFGCIYAEWF-QGKPIFQGRTEIEQMHHIFKMLGTPCEDMWPD--WRYMPDYCKIFFKYKQKFHWWNRFPKCK-

DDIAQPDAIDFLDKLLRYDPTERLTAKEAMKHPYF
    .   ....  .. |.| .|... |. .||.|
----HASENNCEFQMVMYQPYNRWKCMEILQHPWF
Kinase DDB0219953.AA Ciliate-E2 312-597 17 3.9e-42 142.41 In-house 1-365 (365) Show / Hide 
Range on Protein: 312-597
Range on HMM: 1-365/365
Sequence Identity: 17% (73 aa)

YEVIQKIGRGKYSEVFSGIDIETSD-----------------------EVVIKVLKPVQKLKIQREIKILE---------------SLNGGPNIIPLLDS
|..|.|||.| .. |. . ....                         .. .|..|. |.  | .||.|.                ...  |||| . ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VKDQSSKVCSLVFPFVNKTDIRELVY--------------TLDDYDIRYYIFELLK---------------AIDYTHSKG-IIHRDIKPLNIAIDHSKRK
 .... . . ||. ...  | ... .               .... |.|.. ..|.               |. | |||. |||||||| || .      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

LSLIDWGLAEYYHPG----------KNYNVRVA-----------------------SRHYKPPELLVNMFD--------YDYSLDMWSLGCLFAGLILDR
. .||.||. .|..           |.|                            . .|..|| | .  .        |||. |.||||...  ..  .
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

DPFFNGDNNNDQLLKIVKVLGTDDLFNFLDKFGLSLTDEQSSLIKPRQKSNWERFIPYENDDIAQ-------------PDAIDFLDK----LLRYDPTER
 ||                                        ..  .. ... . |  ..| .|             ....|.. |    .| .|| .|
PPF----------------------------------------QQQIKQCKIDFPCPEWQKD-TQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKR

LT-AKEAMKHPYF
.| ......||.|
ITGWEQILNHPWF
Kinase DDB0219953.AA CAMK 317-494 17 1.8e-39 124.38 In-house 1-323 (425) Show / Hide 
Range on Protein: 317-494
Range on HMM: 1-323/425
Sequence Identity: 17% (57 aa)

KIGRGKYSEVFSGIDIETS------------DEVVIKVLK-------------------------------PVQKLKIQREIKILESLNG------GPNI
..||| ...|. .|...|              .| ||...                               |. . ...|||.|. .|.|       |||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IPLLDSVKD-----------QSSK-------VCSLVF---PFVNKT----DIRELV------------------YTLDDYDIRYYIFELLKAIDYTHSKG
| |..   |             ||        . .|.    ..       |. . .                    ..  . |.|.  .. |..| ||..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIHRDIKPLNIAIDHSK----------------RKLSLIDWGLAEYYHP------------------------GKNYNVRVASRHYKP-PELLVN-----
|.|||.|| || .|...                 .. .||.|.| .. |                        |. .. .. . .| . ||.|       
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------MFDYDYSLDMWSLGCL
           |... ||||.|..
MQNATDEEKPYYGPKCDMWSCGVI
Kinase DDB0219953.AA MAPK 465-597 37 8.5e-36 121.14 In-house 192-328 (328) Show / Hide 
Range on Protein: 465-597
Range on HMM: 192-328/328
Sequence Identity: 37% (53 aa)

VASRHYKPPELLVN--MFDYDYSLDMWSLGCLFAGLILDRDPFFNGDNNNDQLLKIVKVLGTDDLFNFLDKFGLSLTDEQSSLIK------PRQKSNWER
|| | |  ||.. |  . .|. . ||||.|| || .. || |.| |..  ||. .|..||||     |. . .    ..  ..|.      ...| .|| 
VATRWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTP-SEEFIQCICM--SEHARNYIQSLGNLPKYPKKPWEK

FIPYENDDIAQPDAIDFLDKLLRYDPTERLTAKEAMKHPYF
 .| .|  .|.|.|||.|.|.|  || .|.|..||. ||||
MFPNANF-NANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase DDB0219953.AA GSK 467-597 28 2.4e-34 101.89 In-house 181-328 (328) Show / Hide 
Range on Protein: 467-597
Range on HMM: 181-328/328
Sequence Identity: 28% (43 aa)

SRHYKPPELLVNMFDYDYSLDMWSLGCLFAGLILDRDPFFNGDNNNDQLLKIVKVLGTDDL-----FNFLDKFGLSLTDEQSSLIKPRQKSNWER-----
||.| .|||. .  .|. . |.||.|| .| ... . |.| ||. .|||  |.|.|||..      .|.  ..     .... . .. .. | .      
SRYYRAPELIFGCTNYTCQIDVWSCGCVMAEMLK-GQPLFPGDSSVDQLVEIIKMLGTPTKEQIQSMNPSYPEFKFPYWSFQQIKPHPWQKNDTKYEYQT

----------FIPYENDDIAQPDAIDFLDKLLRYDPTERLTAKEAMKHPYF
          .. . ..| .  |.||.. |.|.|||..||.. ||..||.|
YYHKKYRTVYMFKWCHTDMQ--DWIDLISKCLVYDPKKRLSPLEACAHPFF
Kinase DDB0219953.AA GSK 312-444 26 4.1e-26 76.26 In-house 1-156 (328) Show / Hide 
Range on Protein: 312-444
Range on HMM: 1-156/328
Sequence Identity: 26% (41 aa)

YEVIQKIGRGKYSEVFSGIDI----ETSDE----VVIKVLKPVQKLKIQREIKILESLN--GGPNIIPLLDSVKDQ-SS-----KVCS-LVFPFVNKTDI
|| ...||.|  . |. ....    ||...    |.||   . .. | .|| .|.. |     |||. |. .   . ..     ..|  ||. ....|  
YEEMKVIGHGSFGVVYQAYMNSPSNETKEIWLGPVAIKKVWQDKRYKCNRELQIMKMLGKLDHPNIVRLKYFFYMHYEKKDENHVYCNCLVMEYMPQTLY

RELVY------TLDDYDIRYYIFELLKAIDYTHSKGIIHRDIKPLNIAIDHSKRKL
... .      ......|..| . ..... | ||.|| |||||| || .|... .|
QVIRHYVKNKQQMPIIHIKLYMYQMFRGLAYLHSHGICHRDIKPQNILVDPDTGVL
Kinase DDB0219953.AA MAPK 312-438 30 1.3e-17 57.31 In-house 1-151 (328) Show / Hide 
Range on Protein: 312-438
Range on HMM: 1-151/328
Sequence Identity: 30% (47 aa)

YEVIQKIGRGKYSEVFSGIDIETSDE------VVIKVLK-PVQKLK----IQREIKILESLNGGPNIIPLLDSVKD-----QSS----KVCSLVFPFVNK
|. ...|| | |  |.| || .|..       |.|| .  | |..     ..||||.|  ... .||| |||  .      |.|    .   .|...   
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELME-

TDIRELVY---TLDDYDIRYYIFELLKA--IDYTHSKGIIHRDIKPLNIAID
|| . . .   .|.|  |.| .. .|..  . | || ..||||.|| ||...
TDLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVN
Kinase DDB0219953.AA ERK 549-597 42 7.4e-15 51.9 In-house 262-307 (307) Show / Hide 
Range on Protein: 549-597
Range on HMM: 262-307/307
Sequence Identity: 42% (21 aa)

RQKSNWERFIPYENDDIAQPDAIDFLDKLLRYDPTERLTAKEAMKHPYF
|.. .||  .|  |   . |.||| |.|.|  ||..|.|..|. .||||
RPPKPWENIFPNAN---CNPQAIDLLEKMLVFDPDKRITVEECLEHPYF
Kinase DDB0219953.AA ERK 465-524 36 1.3e-14 50.99 In-house 177-235 (307) Show / Hide 
Range on Protein: 465-524
Range on HMM: 177-235/307
Sequence Identity: 36% (22 aa)

VASRHYKPPELLVNMFDYDYSLDMWSLGCLFAGLILDRDPFFNGDNNNDQLLKIVKVLGT
||.| |..||.. .  .|. . |.|| || ||...  |.|.| | .  .|.  | ...||
VATRWYRAPEIMLSWQKYTKAMDIWSCGCIFAEMLG-RKPLFPGKDYVHQINRIFQIIGT
Kinase DDB0219953.AA CAMK 556-597 22 1.8e-13 39.1 In-house 365-425 (425) Show / Hide 
Range on Protein: 556-597
Range on HMM: 365-425/425
Sequence Identity: 22% (14 aa)

RFIPYE------------NDDIAQP-------DAIDFLDKLLRYDPTERLTAKEAMKHPYF
.|.|..             ||| .        ...|.. |.|..||..|.|......|| .
DFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase DDB0219953.AA ERK 312-372 38 6.1e-09 29.63 In-house 1-71 (307) Show / Hide 
Range on Protein: 312-372
Range on HMM: 1-71/307
Sequence Identity: 38% (27 aa)

YEVIQKIGRGKYSEVFSGIDIE-----TSDEVVIKVL-----KPVQKLKIQREIKILESLNGGPNIIPLLD
|. |..||.| |  |.| || |     |.. | ||.      .|.    . ||||.|  ..| .||| |.|
YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHENIICLFD
Kinase DDB0219953.AA TyrKc 312-597 17 3.1e-08 -89.45 SMART 1-280 (280) Show / Hide 
Range on Protein: 312-597
Range on HMM: 1-280/280
Sequence Identity: 17% (56 aa)

YEVIQKIGRGKYSEVFSGIDIETSDEVVIKVLKPVQKLKIQREIKILESL-NGGPNIIPLLDSVKDQ-----SSKVCSLVFPFVNKTDIRELV----YTL
 . ..|.|.| . ||. |. .    .| .|.||.  .  . ||..|. .|    |||. |.  . .|     ...   .|. .. . | ..       .|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKL

DDYDIRYYIFELLKAIDYTHSKGIIHRDIKPLNIAIDHSK-RKLSLIDWGLAEYYHPG-------KNYNVRV--ASR-----HYKPPELLVNMFD-YDYS
   |  .. .   .  .| |||..||||.   |. ... .  | |  | ||. . . .       . | ..    ..        .|| .  ..  .   
CMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKIS--DFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYGKFTTK

LDMWSLGCL----FAGLILDRDP-FFNGDNNNDQLLKIVKVLGTDDLFNF----LDKFGLSLTDEQSSLIKPRQKSNWERFIPYENDDIAQPDAIDFLDK
 | || | .    |           .. . .|..... ||  .  .                                  |       .. ..  .   .
SDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMS-------------------------F------VCCPDEMYQIMKQ

LLRYDPTERLTAKEAMKHPYF
  ..|| .| | .|   | .|
CWHEDPEDRPTFSEI--HECF
Kinase DDB0219953.AA ERK 406-435 43 0.001969 8.87 In-house 110-139 (307) Show / Hide 
Range on Protein: 406-435
Range on HMM: 110-139/307
Sequence Identity: 43% (13 aa)

IRYYIFELLKAIDYTHSKGIIHRDIKPLNI
. | .  .| .. | || ..||||.|| ||
CQYFMYQILCGLKYIHSANVIHRDLKPSNI