Gene DDB0216373 (Slime mold)

DDB0216373

Species: Slime mold
Alias: DDB0216373, DdisK098
External Links: DictyBase Link ,
Annotation:

Classification

Group: Other
Family: NAK
Subfamily: MPSK

Sequence

Name Sequence Type Origin Length Description Download
DDB0216373.AA Protein None 369 None Fasta, JSON
DDB0216373.kin_dom Protein Kinase Domain None 345 None Fasta, JSON

Protein domain

Protein domains of DDB0216373.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0216373.AA NAK-Unclassified 22-365 50 2.2e-232 778.32 In-house 1-405 (405) Show / Hide 
Range on Protein: 22-365
Range on HMM: 1-405/405
Sequence Identity: 50% (203 aa)

YTVNRILGEGGFSFVYLVK--------D------NSNSKKYALKVMICQTQESINTAKREINAFQTFN-HENIMKLIDHSIS--NHSQDTKEYRLLLPYY
||..|.|.|||||||||||        |      .|||..|.||.||||..||.||.||||.....|. |.||.|.|||.|.  ||.....|...|..|.
YTIVRYLAEGGFSFVYLVKFSKYINPPDNTASVPHSNSNMYCLKRMICQDEESLNTMKREIDVMKRFRNHPNIVKYIDHHIMRENHNNQSYEVFMLMEYC

KDGTLQDLIDNQRTIYGKDTKKPLFKEKKCLQFFLKVCEAIQVFHNHSP--------------------------------------------PLAHRDI
..|.|||...||||||...|....|.|..|||....||..||..|.|.|                                            ||.||||
SRGSLQDFMNNQRTIYQRLTEQTRFHEQECLQIMSDVCQGIQCMHQHQPRQDNATSRVNVDAVSMTYSDETAMLLEDTPLEMDMLSSNSAGSIPLIHRDI

KPGNIVLQNLRRPSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSEDSDIEAIPILMDFGSVREARIKIENRKDALSLQDEVE
|..|....|||||||||||||||||||||||||||||||||||||||||||||||||||||||||....|..|.||||..|..|.||||.....|||...
KIENVLFCNLRRPSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSEDSEHNGIYKLCDFGSCCECIITIENRQEMQYLQDWIN

QNTTPFYRAPELFDIPSDCQIDERIDVWALGCLLYTMAYNNSPFEVCDNEPNGSVALKVLSGLPKPFPPSQTNYSNQFNQLIIDMVNLDKDERLHLNQVI
..|||.|||||..|....|.|||.||.|||||.||.|.....|||.|....|.||..|.|.||.|...||..|||||...||..|.|.|...|....||.
MHTTPQYRAPEMIDLYRCCPIDEKIDIWALGCFLYKMCFYTTPFEMCGQLHNASVTYKILHGLGKYEFPSNHNYSNQLHNLIKIMLNEDPIQRPNIYQVL

ERINQ
..|.|
NHICQ
Kinase DDB0216373.AA NAK 22-363 32 1e-157 530.15 In-house 1-299 (299) Show / Hide 
Range on Protein: 22-363
Range on HMM: 1-299/299
Sequence Identity: 32% (117 aa)

YTVNRILGEGGFSFVYLVK---------DNSNSKKYALKVMICQT-QESINTAKREINAFQTFNHENIMKLIDH-SISNHS--QDTKEYRLLLPYYKDGT
|||...|.|||||.||||.         .|||..||||| |||.. ....|..||||.......|.|....... .|....  ..|.|..||..|...|.
YTVEKYLAEGGFSYVYLVQDNYINHPDNPNSNGEKYALKRMICHSDEQDLNACKREIEMMKKLQHHNNIVQYIDSHINERDDSNGTWEVFLLMEYCCHGS

LQDLIDNQRTIYGKDTKKPLFKEKKCLQFFLKVCEAIQVFHNHSP--PLAHRDIKPGNIVLQNLRRPSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
|.||......     .|.. |.|...||.|..|||..|..|.  |  |..|||||..|| |...                                    
LWDLMNKRLM-----DKGTCFTEDEILQIFCDVCEGVQAMHQCQPPKPIIHRDIKIENILLSES------------------------------------

NNNNNNNNNNNNNNNSEDSDIEAIPILMDFGSVREARIKIENRKDALS---LQDEVEQNTTPFYRAPELFDIPSDCQIDERIDVWALGCLLYTMAYNNSP
                   ... ...|.||||...|.|..|||..|..   .||.....|||.|||||..|. |.|.|||..|.|||||.||.|.....|
-------------------HHDGNYKLCDFGSMTTAIIQPENRWEAQYRSMVQDWINKYTTPMYRAPEMCDLYSNCPIDEKVDIWALGCMLYKMCFYTHP

FEVCDNEPNGSVALKVLSGLPKPFPPSQTNYSNQFNQLIIDMVNLDKDERLHLNQVIERI
|| |..... |..|....| .|...|....||.|...||..| . | ..|.. .||....
FEDCYQRHD-SSKLAIQNGNYKYSIPDNSRYSQQMHDLIRYMLTPDPEQRPNIYQVLNQL
Kinase DDB0216373.AA Ciliate-E2 22-361 15 1.2e-37 126.77 In-house 1-361 (365) Show / Hide 
Range on Protein: 22-361
Range on HMM: 1-361/365
Sequence Identity: 15% (70 aa)

YTVNRILGEGGFSFVYLVKDNSNSKKYA--------------------LKVMICQTQESINTAKREINAFQTFN----------------HENIMKLIDH
| .....|.|.|. ||..|. .. |..|                    .. | .. .  |.  |.||. ... |                | ||.|....
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

SISNHSQDTKEYRLLLPYYKDGTLQDLIDNQRTIYGKD--TKKPLFKEKKCLQFFLKVCE---------------AIQVFHNHSPPLAHRDIKPGNIVLQ
 ..   .|.. . | . |.. |.|.|.| |...  ..    .   |.||...... ....               |..  |.  .   |||||| ||.. 
FQE---KDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN-IIHRDIKPENILF-

NLRRPSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSEDSDIEAIPILMDFGSVREARIKIENRKDALSLQDEVEQNT-----
                                                              . . |||  ... .. .|| . .... .  .       
--------------------------------------------------------------IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSR

-------------------TPFYRAPELFDIPS------DCQIDERIDVWALGCLLYTMAYNNSPFEVCDNEPNGSVALKVLSGLPKPFPP---------
                   || | ||| .   .        . |. .|.|.||..|| | ... ||             . . .  . ..|         
TPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-----------QQQIKQCKIDFPCPEWQKDTQCI

-----SQTNYSNQFNQLIID----MVNLDKDERLH-LNQVIE
     |  . |..  .||      | . | ..|.   .|...
QCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN
Kinase DDB0216373.AA MPSK 231-363 39 3e-36 126.73 In-house 152-281 (281) Show / Hide 
Range on Protein: 231-363
Range on HMM: 152-281/281
Sequence Identity: 39% (52 aa)

PILMDFGSVREARIKIENRKDALSLQDEVEQNTTPFYRAPELFDIPSDCQIDERIDVWALGCLLYTMAYNNSPFEVCDNEPNGSVALKVLSGLPKPFPPS
|..||.||  ||.|... . .|. |||. ..  .  ||||||| . | | ||||.|.| ||| || |.| .||..    .   ||.| |...  . .| .
PVIMDLGSMNEACIQVKGQRQACALQDWAAERCSMVYRAPELFHVQSHCVIDERTDIWSLGCVLYAMCYFHSPYDMI-YQRGDSVHLAVQNRNFN-IPEN

QTNYSNQFNQLIIDMVNLDKDERLHLNQVIERI
   ||    |||  |   |  || |   |  ..
-SRYSQDMHQLISYMMRVDPMERPHIFWVLNQT
Kinase DDB0216373.AA S_TKc 22-367 17 7.6e-36 126.32 SMART 1-231 (231) Show / Hide 
Range on Protein: 22-367
Range on HMM: 1-231/231
Sequence Identity: 17% (61 aa)

YTVNRILGEGGFSFVYLVKDNSNSKKYALKVMICQTQESINTAKREINAFQTFNHENIMKLIDHSISNHSQDTKEYRLLLPYYKD--GTLQDLIDNQRTI
|.. |..|.|.|. ||......  ...|.|..        ....|||.  .  .|.|| ||.|.  .      ... . . |     |.| |.|..... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIKKRGRH

YGKDTKKPLFKEKKCLQFFLKVCEAIQVFHNHSPPLAHRDIKPGNIVLQNLRRPSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
 ..      | |  .  ..  .|.|..  |.|     |||.|| || | .                                                  
GLRF----PFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE--------------------------------------------------

NNSEDSDIEAIPILMDFGSVREARIKIENRKDALSLQDEVEQNTTPFYRAPELFDIPSDCQIDE-RIDVWALGCLLYTMAYNNSPFEVCDNEPNGSVALK
             . |||. |.                   .  ||.|.|||..      . .  ..|.|..||.|| |..   ||.      .  . .|
----------HIKICDFGLARQL----------------TTFCGTPWYMAPEVL------GYGKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFK

VLSGLPKPFPPSQTNYSNQFNQLIIDMVNLDKDERLHLNQVIE-----RINQII
..              | .. ..|  . . | ..|.   .. .     .. . .
KIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DDB0216373.AA MPSK 22-167 36 3e-32 113.03 In-house 1-146 (281) Show / Hide 
Range on Protein: 22-167
Range on HMM: 1-146/281
Sequence Identity: 36% (55 aa)

YTVNRILGEGGFSFVYLVKDNSNSKKYALKVMICQTQESINTAKREINAFQTFNHENIMKLIDH-SISNHS----QDTKEYRLLLPYYKDGTLQDLIDNQ
|.. . ||||||| | || . .  ..||||   |  |.  | |.||.     |.|.||. |.|  ..          . |  |.|||.| |||.| ..  
YYFMQRLGEGGFSYVDLVENLHDGHFYALKRIQCHEQQDQNQAQREAEMHCQFDHPNIIRLVDWGCLKGREDIVINTKHEIWLVLPYFKHGTLWDHLQRM

RTIYGKDTKKPLFKEKKCLQFFLKVCEAIQVFH-NHSPPLAHRDIKPGNIVL
        |     | . .. || ||| .   |     |.||||.||.|| |
K------DKGDCMTEDQIWWIFLGVCEGLKAIHEAMPKPYAHRDMKPTNICL
Kinase DDB0216373.AA Pkinase 22-363 17 1.4e-31 112.75 Pfam 1-293 (293) Show / Hide 
Range on Protein: 22-363
Range on HMM: 1-293/293
Sequence Identity: 17% (67 aa)

YTVNRILGEGGFSFVYLVKDNSNSKKYALKVMICQTQESIN--TAKR--EINAFQTFNHENIMKLIDHSISNHSQDTKEYRLLLPYYKDG----TLQDLI
|.. |..|.|.|. ||. .. ...|..|.|..  ....|    |. |  ||   . .||.|| .|.|   .      ... . ..|   |     | |.|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-----KDHIYMVMEYCEGGLYVMDLFDYI

DNQRTIYGKDTKKPL-FKEKKCLQFFLKVCEAIQVFHNHSPPLAHRDIKPGNIVLQ-NLRRPSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
         . .... | |. |  ... ......  |..     |||.|| || .  |   ..                                     
ST-------WRHGCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDA-------------------------------------

NNNNNNNNNNSEDSDIEAIPI-LMDFGSVREARIKIENRKDALSLQDEVEQNTTPFYRAPELFDIPSDCQIDERIDVWALGCLLYTMAYNNSPFEVC---
                   .. . |||. . ..          . .       ||.|.|||.  | ..  .. ..|.|..||.|| |.  . ||  .   
-------------------CVKICDFGLAKQFD--------Y-NNS-MTTFCGTPWYMAPEV--IRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWH

DNEPNGSVALKVLSGLPKPFPPSQTNY------------------SNQFNQLIIDMVNLDKDERLHLNQVIER--I
||  .  . ..   | | .|. ....                   |  . ..| .. ..|  .|.   |. .   .
DN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase DDB0216373.AA CAMK 27-361 15 4.9e-26 80.29 In-house 1-421 (425) Show / Hide 
Range on Protein: 27-361
Range on HMM: 1-421/425
Sequence Identity: 15% (72 aa)

ILGEGGFSFVYLVKDNSNS------------KKYALKVMICQ----------------------------TQESINTAKREINAFQT-------FNHENI
.||.|.|. |.|... ..             .|.| |..  .                            ....    .|||.  ..        .|.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

MKLIDHSISNHS--------QDTK-------EYRLLL---PYYKDG----TLQDLIDNQRTIYGKDTKKPL---------FKEKKCLQFFLKVCEAIQVF
 ||...  ..|           .|       .. . .    |   |     | | |  ..  . ..              |.|. . ..|  .|.|..  
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEF----DQFDIVERGRFTEREARRYFRQICSAVHYC

HNHSPPLAHRDIKPGNIVLQNLRRPSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSEDSDIE------AIPILMDFGSVREA
|.|    .|||.|| || |..  . |..     .                                             |      .   . |||  .. 
HSHN--IVHRDLKPENILLDDNNDDSDP-V-E-HD--------------------------------------------EIFDWNNNNIKIIDFGFANKF

RIKIENRKDALSLQDEVEQNT----------------TPFYRA-PELFDIPS-----------DCQIDERIDVWALGCLLYTMAYNNSPFEV--------
. . .|....   . |   ..                || | | ||..   .              ... .|.|..|..||.|    .||.         
DPGENNFMCSDYKGGE-M-HNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICE

------CDNEPNGSVALKVLSGLPKPFPP-----------------SQTNYSNQFNQLIIDMVNLDKDERLHLNQVIE
      .|.|    .     .  |..|.|                 .. . | .  .||  | . | ..|. . |. .
DEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH-FVSQECKDLIRKMLQVDPEKRMTIEQCLN
Kinase DDB0216373.AA BIKE 23-169 33 5.3e-25 86.49 In-house 2-141 (267) Show / Hide 
Range on Protein: 23-169
Range on HMM: 2-141/267
Sequence Identity: 33% (49 aa)

TVNRILGEGGFSFVYLVKDNSNSKKYALKVMICQTQESINTAKREINAFQTFN-HENIMKLIDHSISNHSQDTKEYRLLLPYYKDGTLQDLIDNQRTIYG
||.  | ||||. |.||.|...  |.||| |  . .. .| ..||.   .    | ||.  .| .| . ...  |  .| .| .   . ... |||   |
TVEEQLAEGGFAMVFLVRDHKG-NKCALKRMYVNNEHDLNVCCREHQIMKQCSGHKNIVGYVDCYINCIGNGVWECMILMEYCRH-QVVNMM-NQRLQQG

KDTKKPLFKEKKCLQFFLKVCEAIQVFHNHSPPLAHRDIKPGNIVLQN
.      | |.  || |  ||||.   |.   |  ||| |  || |..
Q-----YFTEQEVLQIFCDVCEAVSRLHHCQTPIIHRDLKVENILLHD
Kinase DDB0216373.AA TKL 28-363 12 3.8e-24 83.85 In-house 1-364 (364) Show / Hide 
Range on Protein: 28-363
Range on HMM: 1-364/364
Sequence Identity: 12% (55 aa)

LGEGGFSFVYLVKDNSNS--------KKYALKVMICQ---------------------------TQESINTAKREINAFQTFNHENIMKLIDHSISNHS-
.|.|||. ||  | . ..        |  | |..  .                           ..    . ..||.    ..|.|| ...  .... . 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-------QDTKEYRLLLPYYKDGTLQDLIDNQRTIYGKDTKKPLFKEKKCLQFFLKVCEAIQVFHNHS------PPLAHRDIKPGNIVLQNLRRPSNNNN
       . .... .   |.. |.| ...                   . ... | .. ...  |..       ||..|||.|. || . .  .. . | 
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVS-NY

NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSEDSDIEAI-------PILMDFGSVREARIKIENRKDALSLQ----------DEVEQ
                                                   .       . . |||  |.   . .. . . . .              |
M--------------------------------------------------YNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQ

NTTPFYRAPELFD---IPSDC----------QIDERIDVWALGCLLYTMAYNNSPFEVCDNEPNGSV-------ALKVLSGLPKPFP---------PSQT
  || . |||...     ...          . .|..||.. | .|. ..    |..  ...|           .. .. ||. | |         .  .
CGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCP

NYSNQFNQLIIDMVNLDKDERLHLNQVIERI
.   .. .|. |  . | ..|.  .....|.
DCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase DDB0216373.AA Ciliate-E2-Unclassified 22-305 16 9e-22 72.32 In-house 1-271 (352) Show / Hide 
Range on Protein: 22-305
Range on HMM: 1-271/352
Sequence Identity: 16% (54 aa)

YTVNRILGEGGFSFVYLVKDNSNSKKYALKVMI-------CQTQESINTAKREINAFQTFN-------------------HENIMKLIDHSISNHSQDTK
|......|.|||. ||....... ..||.| |.       .| ....   ..|... .  .                   |..|.|....      ||..
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCF-----QDKQ

EYRLLLPYYKDGTLQDLIDNQRT-------IYGKDTKKPLFKEKKCL-----QFFLKVCEAIQVFHNHSPPLAHRDIKPGNIVLQNLRRPSNNNNNNNNN
   . . | ..|.|.. | .. .       .. .  ..  | |....     ..|  ......  |       |||||| ||...|  .           
NIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKN-NIIHRDIKPENILFDNNGK-----------

NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSEDSDIEAIPILMDFGSVREARIKIENRKDAL-----SLQDEVEQNT--TPFYR----APEL
                                               . . |||. ..    .... .        ....  . .  || |     |||.
--------------------------------------------NYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEV

FDIPSDCQIDER----IDVWALGCLLYTMAYNNSPFE
..    .. |..    .|.|.||..|| | ... ||.
LQ---GQNYDHSKAYKCDIWSLGVILYEMLFGYYPFY
Kinase DDB0216373.AA GAK 255-363 35 7.3e-20 62.61 In-house 176-277 (277) Show / Hide 
Range on Protein: 255-363
Range on HMM: 176-277/277
Sequence Identity: 35% (39 aa)

LQDEVEQNTTPFYRAPELFDIPSDCQIDERIDVWALGCLLYTMAYNNSPFEVCDNEPNGSVALKVLSGLPK-PFPPSQTNYSNQFNQLIIDMVNLDKDER
..||   .||| || ||  |. |   | .. |.||.||.||.|.|   |||        . .| .  |  . | || .. |.  |  ||  .   . |||
VEDEMFRHTTPMYRSPEMCDLYSNWPIGHKQDIWAMGCMLYFMCYRQHPFE-------DGAKLRIINGNYMKPIPPQDNQYM-CFHDLIRACLQVNPDER

LHLNQVIERI
|   .|.| .
LDIAMVVEYM
Kinase DDB0216373.AA GAK 22-161 33 4.8e-17 53.1 In-house 1-137 (277) Show / Hide 
Range on Protein: 22-161
Range on HMM: 1-137/277
Sequence Identity: 33% (49 aa)

YTVNRILGEGGFSFVYLVKDNSNSKKYALKVMICQTQESINTAKREINAFQTFN-HENIMKLIDHSISNHS---QDTKEYRLLLPYYKDGTLQDLIDNQR
| | ... |||| |||.  |    . |||| |.    .       ||.       ||||  ..| |    .   |  .|| ||  | | . | |.     
YRVRCVIAEGGFAFVYVAQDVQTGREYALKRMLSHDMQANRAIINEICMMKKLQGHENIVQFCDASYISREESNQSQAEYLLLMEYCKFSQLVDCL----

TIYGK--DTKKPLFKEKKCLQFFLKVCEAIQVFHNHSPPLAHRDIK
    |  . .|| |     |  |   | |.|  |  .|| .|||||
----KRMECYKP-FSCDCVLRIFYQMCRAVQHMHSQKPPIIHRDIK
Kinase DDB0216373.AA TKL-ciliate1 235-304 30 3.8e-15 48.28 In-house 148-219 (279) Show / Hide 
Range on Protein: 235-304
Range on HMM: 148-219/279
Sequence Identity: 30% (22 aa)

DFGSVREARIKIENRKDALSLQDEVEQNTTPFYRAPELFD--IPSDCQIDERIDVWALGCLLYTMAYNNSPF
.|..|  | .      .  ..| |.. |||. ..||| .|  | .. .| |.||..|.| ..| .. .  ||
NFPHVKIADFHRIRNCSFQDMQNEMQRNTTFHWMAPEQMDPHIFPNYPINEKIDIYAYGIVMYILCFRKTPF
Kinase DDB0216373.AA BIKE 256-305 46 7.4e-13 42.35 In-house 171-220 (267) Show / Hide 
Range on Protein: 256-305
Range on HMM: 171-220/267
Sequence Identity: 46% (23 aa)

QDEVEQNTTPFYRAPELFDIPSDCQIDERIDVWALGCLLYTMAYNNSPFE
.||.|..||  |||||. |. |. .|  . |.|||||.|| . .   ||.
KDEIEKYTTMCYRAPEMIDLYSGKEITTKADIWALGCMLYKLCFFCLPFG
Kinase DDB0216373.AA TyrKc 22-363 13 3.9e-05 -139.64 SMART 1-280 (280) Show / Hide 
Range on Protein: 22-363
Range on HMM: 1-280/280
Sequence Identity: 13% (52 aa)

YTVNRILGEGGFSFVYLVKDNSNSKKYALKV---MICQTQESINTAKREINAFQTF--NHENIMKLIDHSISNHSQDT---KEYRLLLPYYKDGTLQDLI
 | ...|||| |  ||. . .       ..|   |.      .    ||..    .  .|.|| .|.   ..   .     . . ... | . | |.| .
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN-FMYIEPLMIVMEYMPHGDLKDYL

-DNQRTIYGKDTKKPLFKEKKCLQFFLKVCEAIQVFHNHSPPLAHRDIKPGNIVLQNLRRPSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
 .....          .. |. |.| . ...  .  | .  .. |||.   |. . . .                                         
RKHRPK----------LCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENH-----------------------------------------

NNNNNNNNNSEDSDIEAIPILMDFGSVREARI-------KIENR------KDALSLQDEVEQN--TTPFYRAPELFDIPSDCQIDERIDVWALGCLLY-T
                             ..|       .|..       ||  . . .   .        ||| .    ..   .  |||. | ...  
----------------------------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---NYGKFTTKSDVWSFGVCMWEI

MAYNNSPFEV-----CDNEPNGSVALKVLSG--LPKPFP--------PSQTNYSNQFNQLIIDMVNLDKDERLHLNQVIERI
. |  .| .      ..|.    |  .| .|  .|.|           ..  |     |.. .  . | ..|   ....|..
FTYGQQPYPGMIQQMMSNQ---EVIEYVKQGYRMPQPPNDYPMSFVCCPDEMY-----QIMKQCWHEDPEDRPTFSEIHECF
Kinase DDB0216373.AA TKL-ciliate1 334-363 16 0.002982 6.98 In-house 250-279 (279) Show / Hide 
Range on Protein: 334-363
Range on HMM: 250-279/279
Sequence Identity: 16% (5 aa)

YSNQFNQLIIDMVNLDKDERLHLNQVIERI
..  |..|....   .   |   |..|...
CPQNFHNLMMRCWCQNPNKRPNFNEIIQIL
Kinase DDB0216373.AA BIKE 329-362 29 0.014477 4.94 In-house 234-267 (267) Show / Hide 
Range on Protein: 329-362
Range on HMM: 234-267/267
Sequence Identity: 29% (10 aa)

PSQTNYSNQFNQLIIDMVNLDKDERLHLNQVIER
|. ..||..  .||  | . | . |    || . 
PDNSKYSREMHCLIRYMLEPDMEKRPDIYQVSHV
Kinase DDB0216373.AA TKL-ciliate1 149-167 47 0.063377 2.37 In-house 120-138 (279) Show / Hide 
Range on Protein: 149-167
Range on HMM: 120-138/279
Sequence Identity: 47% (9 aa)

HNHSPPLAHRDIKPGNIVL
|   .|| |||.|  || .
HMRQNPLIHRDLKMQNILY