Gene DDB0229334 (Slime mold)

DDB0229334

Species: Slime mold
Alias: DDB0229334, DdisK106
External Links: DictyBase Link ,
Annotation:

Classification

Group: Other
Family: Other-Unique

Sequence

Name Sequence Type Origin Length Description Download
DDB0229334.AA Protein None 317 None Fasta, JSON
DDB0229334.kin_dom Protein Kinase Domain None 198 None Fasta, JSON

Protein domain

Protein domains of DDB0229334.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0229334.AA STE 16-199 20 9.1e-29 98.76 In-house 74-359 (359) Show / Hide 
Range on Protein: 16-199
Range on HMM: 74-359/359
Sequence Identity: 20% (60 aa)

NNENEIYKLKKLN--HPSIIKHYDIDEKKS-----EKNVIIYQESINGGISIDKFDNNN--------------FFSQEVIREICEQILLA-LRFMDNHQI
. ..||  .||.|  || |.| |.  .|..     . .. |. | ..||   |  ...               .|. ..|. || ||| . | .  .|.|
QILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHI

VHRDLNCSNVIIFPETLTIKIIDFGVTK-------------------TNFLN-------QDYQSPEVLKS------NNFTHKSDIWSFGFIL-------L
.|||. ..|. .      .|..|||| .                   |.  .       . . .|||..       .  . |.||||.|  .        
IHRDIKPANILL------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKP

KMID-KSL-----------------------NNIPDDLP----------------------TEQFDFLHSCLATNLSDRLDAQTLLH--HPFI
 . | . .                       ...|   .                       |  ||.  ||  . ..| .|. ||.  ||||
PWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase DDB0229334.AA Ciliate-E2 7-199 18 7.7e-28 92.63 In-house 55-365 (365) Show / Hide 
Range on Protein: 7-199
Range on HMM: 55-365/365
Sequence Identity: 18% (60 aa)

IRKINKLNYNNENEIYK--------------LKKLNHPSIIKHYDIDEKKSEKNVIIYQESINGGISID--KFDNNNF---------FSQEVIREICEQI
..| .. . ..|. |..              |..|||| ||| |.  . |...|. .  | ..||   |  |  . ..         |. . |..| .||
MKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQI

LL---------------ALRFMDNHQ-IVHRDLNCSNVIIFPETLTIKIIDFGVTK---------------TNFLNQD----------------------
|                ||... .   |.|||.  .|...      |||||||  |                ....                        
LQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTI

-----YQSPEVLKSNN---------FTHKSDIWSFGFILLKMIDKSL------NN----------------------IPDDLPTEQFDFLHS----CLAT
     |..||.|.. .          ..|.||||.| ||  |. . .       .                      ...... |  |..      .|  
CGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPFQQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQK

NLSDRLD-AQTLLHHPFI
. . |.. .. .| ||..
DPEKRITGWEQILNHPWF
Kinase DDB0229334.AA Dicty3 5-194 19 3.5e-24 76.57 In-house 30-351 (351) Show / Hide 
Range on Protein: 5-194
Range on HMM: 30-351/351
Sequence Identity: 19% (63 aa)

CDIRKINKLNYN-----NENEIYKLKKLNHPSIIKHYD--IDEKKSEKNVIIYQESINGGISIDK--------FDNNNFFSQEVIREICEQILLALRFMD
| | .|||   |     ....|. .||..||.|.| |   . ..... |. || | |.|.|.| .         ..||.|. . |..| ......| .  
CHIKIINKCDFNEVNNWRHEKII-NKKMRHPCIVKYYGACYCCDNNNDNHYIYMEYIEGEIPISFVKTNNMLKKHKNNRFNEHEISKIICDLVKTLNYIH

NH-QIVHRDLNCSNVIIFPETL-------------------------TIKIIDFGVTK------------------------------------------
.. .|.|||..| |...  .                           ..|.||||  |                                          
KNCHIIHRDIKCDNIMLDNDEQHQCNNNNNKMSSTCRDIQCYYSNEINWKLIDFGLSKNISYYSNNNNNNNYNNNNNNNNNNNNNNNNNNNNNNNNNNNN

------TNFLN-------------------QDYQSPEVLKSNN--FTHKSDIWSFGFILLKMI--D-----KSLN-----------N-----IPDDLPTE
       .. |                     | .||... |.   . ||||||.| ....|   .     ...|           |     ||| ..  
NNTNNNVKIINNNIYSNKQYKQKCYSICGTIHYMAPEIKLNNQCCACRKSDIWSLGCTVWEMVGGNLCHCEQDINEMAFMVNDNKQNIWIPQIPDHVSNF

QFDFLHSCLATNLSDRLDAQTLL
  .|.  |. .. . | |.  |.
CKNFIQHCWQIDPNHRWDMHELI
Kinase DDB0229334.AA Ciliate-E2-Unclassified 5-157 19 7.2e-24 79.69 In-house 33-264 (352) Show / Hide 
Range on Protein: 5-157
Range on HMM: 33-264/352
Sequence Identity: 19% (46 aa)

CDIRKINKLNYNNE----NEIYKLKKLN-----------------HPSIIKHYDIDEKKSEKNVIIYQESINGG-----ISIDKF------------DNN
..|.........|.    ||.  .....                 ||.... ..........|..|  | ..||     |.. |.             ..
KKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQR

NFFSQEVIR-----EICEQILLALRFMDNHQ-IVHRDLNCSNVIIFPETL--TIKIIDFGVTK--------------------TNFLNQD-----YQ---
. |. . ..      .. |||..| ..   . |.|||. ..|...  .     |||||||  |                     . ...      |.   
KIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQY

-SPEVLKSNNFT----HKSDIWSFGFILLKMI
 .||||...|      .|.||||.| ||  |.
TAPEVLQGQNYDHSKAYKCDIWSLGVILYEML
Kinase DDB0229334.AA Pkinase 12-157 26 5.3e-17 61.19 Pfam 40-206 (293) Show / Hide 
Range on Protein: 12-157
Range on HMM: 40-206/293
Sequence Identity: 26% (46 aa)

KLNYNNEN--EIYKLKKLNHPSIIKHYDIDEKKSEKNVIIYQESINGG---ISIDKFDN---NNFF--SQEVIREICEQILLALRFMDNHQIVHRDLNCS
. .... .  ||. .|.|||| |.. ||. |   .... . .|  .||   ..   .     .. |  | .... .. ||| .| .. .. |.||||  .
WKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPE

NVIIFPETLTI----KIIDFGVTKT--NFLNQDYQS---------PEVLK-SNNFTHKSDIWSFGFILLKMI
|. |  .. .|    ||.|||. |   .  |. ...         |||.. ..  ..|.|.||.| ||  |.
NILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEML
Kinase DDB0229334.AA CAMK 5-150 18 5.7e-17 50.54 In-house 55-321 (425) Show / Hide 
Range on Protein: 5-150
Range on HMM: 55-321/425
Sequence Identity: 18% (51 aa)

CDIRKINKLNYNN-------------ENEIYKLKK-------LNHPSIIKHYDIDEKKS-----------------EKNVIIYQ---ESINGG----ISI
| . ||.| .  .             ..||  .||       |.|| ||| |.. | ..                 .|....     | . ||       
C-Y-KIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLF

DKFDNNNF---------------FSQEVIREICEQILLALRFMDNHQIVHRDLNCSNVIIFPET----------------LTIKIIDFGVTKTNFLNQ--
|.   .                 |. .  | .  ||. |.... .| |||||| . |. .                     .|||||||  .  . ..  
DYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENN

-------------------------------DYQS-PEVLKSNN--------------FTHKSDIWSFG
                                | . ||||...                . |.|.|| |
FMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCG
Kinase DDB0229334.AA Other-Unique 2-192 16 1.6e-15 49.58 In-house 3-249 (249) Show / Hide 
Range on Protein: 2-192
Range on HMM: 3-249/249
Sequence Identity: 16% (42 aa)

DIECDIRKINKLNYNNENEIYKLKKLNHPSIIKHYDIDEKKSEKNVIIYQESIN------------GGISIDKFDNNNFFSQEVIREICE----------
||.    .  .....|... |  ||..|. | .  | |..|.| ....||  |.            ......... ..... ... ..||          
DIGKGTYGRVYKQHHNKKKKYCAKKTKHHKI-HCMDMDNNKRE-QIYHYQ-IIHCIFYWTMNHCHLCFCYEHCPNMIFYIMYPWYHHHCECQCQCEHWMN

--QILLALRFMDNHQIVHRDLNCSNVIIFP------------------ETLTIKIIDFGVTKTNFLNQDYQ------SPEVLKSNNFTHKSDIWSFGFIL
  .....|..  |....|.|.|..|..|                    |.. |||.||.     .......      |||  .  ....|.|...||...
CCHMIHNLHHLHNNNHIHCDINPNNIWINQNNIHMCHNCGHNIPTIIIEHQHIKIMDFNNN-N-MMYFAPEFSCRWCSPETFDYWPLGEKIDQYHFGCYH

LKMI---------------DKSLNNIPDDLPTEQFDFLHSCLATNLSDRLDAQT
..|.               ..  .. .  .. .| ...|.|. .|.........
FHMNCQHWIFHYHDVQHWPPHESPKDI-HILICQCECCHQCM-VNPYQNPNCFY
Kinase DDB0229334.AA TK 59-150 15 4.4e-15 46.26 In-house 187-381 (486) Show / Hide 
Range on Protein: 59-150
Range on HMM: 187-381/486
Sequence Identity: 15% (30 aa)

SIDKFDNNNFFSQEVIRE-----------------------------------ICEQILLALRFMDNH------QIVHRDLNCSNVIIFPETL-------
|... . .  . |... .                                   .| ||  .....  .      ..||||| . |. .. .         
SHESNSPC-PEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDG

---TIKIIDFG--------VTKTNFLNQDY------------------------------------QSPEVLK---------SNNFTHKSDIWSFG
   ..|| |||         ..    ..||                                     .||.|.          . ||.|||.||||
CGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFG
Kinase DDB0229334.AA S_TKc 3-199 25 2.3e-14 33.82 SMART 19-231 (231) Show / Hide 
Range on Protein: 3-199
Range on HMM: 19-231/231
Sequence Identity: 25% (60 aa)

IECD------IRKINKLNYNNENEIYKLKKLNHPSIIKHYDIDEKKSEKNVIIYQESING--GISIDKFDNNNF------FSQEVIREICEQILLALRFM
.. .      | .|.    . ..||  ||| .|| |.| ||. .    ... .  | ..|  |   |  ....       |.  ..| .. ||..|| ..
RHKKTGRIVAIKIIK---EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYC

DNHQIVHRDLNCSNVIIFPETLTIKIIDFGVTKTNFLNQ-----DYQSPEVLKSNNFTH-KSDIWSFGFILLKMID---------KSLNNIPDDLPTEQF
 .|.|.||||  .|. .     .|||.|||. .    .      .| .||||    ... |.|.||.| ||  |.          . ...|    . |  
HSHGIIHRDLKPENILLDE---HIKICDFGLARQL--TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFPQMQMMFKKIG---SPEAK

DFLHSCLATNLSDRLDAQTLLH-------HPFI
||.  ||  . ..|. |  .|.       ||..
DFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DDB0229334.AA CAMKL 6-157 26 2.5e-12 35.48 In-house 34-230 (297) Show / Hide 
Range on Protein: 6-157
Range on HMM: 34-230/297
Sequence Identity: 26% (52 aa)

DIRKINKLNYNNEN--------------EIYKLKKLN---HPSIIKHYDIDEKKSE----KNVIIYQESINGGI--SIDKFDNNNF----FSQEVIREIC
|..||..  ... |              ||  .|.||   || ||| |.. | ..     | . .  | . ||     |. ...      .. .  | . 
DKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYF

EQILLALRFMDNHQIVHRDLNCSNVIIFPETL-TIKIIDFGVT-----K----TNFLNQD-----YQSPEVLKS--NNFT-HKSDIWSFGFILLKMI
 ||. |. .. .| |||||.   |. .      .|||||||       .     ..|.       |..||....    .   | |||| | ||  |.
RQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMV
Kinase DDB0229334.AA CMGC 68-118 27 1.4e-11 33.4 In-house 178-249 (513) Show / Hide 
Range on Protein: 68-118
Range on HMM: 178-249/513
Sequence Identity: 27% (20 aa)

FFSQEVIREICEQILLALR--FMDNHQ--IVHRDLNCSNVIIFPETLT-------------------IKIIDFG
.|.   || .. ||| .|   ..  |   |.||||  .|. | ...                     .||.|||
YFMI-HIR-YMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFG
Kinase DDB0229334.AA TyrKc 3-199 16 6.9e-09 -78.95 SMART 1-280 (280) Show / Hide 
Range on Protein: 3-199
Range on HMM: 1-280/280
Sequence Identity: 16% (47 aa)

IECDIR--------------------KINKLNYNNE---NEIYKLKKL--NHPSIIKHYDIDEKKSE-----KNVIIYQESINGGISIDKF--DNNNFFS
|. .                      |  | .   |   .|.  ..||  .|| |.. | .  ....     . . |  |   .  . ...  .. . ..
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPH-GDLKDYLRKHRPKLC

QEVIREICEQILLALRFMDNHQIVHRDLNCSNVIIFPETLTIKIIDFGVTKTNFLN-------QDYQ----------------SPEVLKSNNFTHKSDIW
 .   ..| ||    ..   ....|||| . |. .  .  |.|| ||| ..            . |                 .||... . ||.|||.|
MKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVW

SFG---------------------FILLKMIDKSLNN----IPDD--------LPTEQFDFLHSCLATNLSDRLDAQTLLHHPFI
|||                          .| .  .     .|..         |.| ..   .| . . .||   ...  | ..
SFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase DDB0229334.AA PAKA 174-199 53 9e-09 27.06 In-house 235-260 (260) Show / Hide 
Range on Protein: 174-199
Range on HMM: 235-260/260
Sequence Identity: 53% (14 aa)

DFLHSCLATNLSDRLDAQTLLHHPFI
|||  ||  .  .| .||.||||||.
DFLDKCLCVDVDRRASAQELLHHPFL
Kinase DDB0229334.AA Pkinase_Tyr 90-150 31 3e-06 21.85 Pfam 129-201 (270) Show / Hide 
Range on Protein: 90-150
Range on HMM: 129-201/270
Sequence Identity: 31% (23 aa)

NHQIVHRDLNCSNVIIFPETLTIKIIDFGVTKTNFLNQDY-Q------------SPEVLKSNNFTHKSDIWSFG
.....|||| . |. .  |....|| ||| ... .    | .            .||... . ||.|||.||||
SKNCIHRDLAARNCLVT-ENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFG
Kinase DDB0229334.AA Ciliate-E2-Unclassified 164-199 27 3e-06 17.86 In-house 313-352 (352) Show / Hide 
Range on Protein: 164-199
Range on HMM: 313-352/352
Sequence Identity: 27% (11 aa)

IPDDLPTEQFDFLH----SCLATNLSDRLDAQTLLHHPFI
||.... |. ||.     ..|  |.. |.... .| ||..
IPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase DDB0229334.AA CMGC 132-199 12 4e-06 15.11 In-house 394-513 (513) Show / Hide 
Range on Protein: 132-199
Range on HMM: 394-513/513
Sequence Identity: 12% (15 aa)

PEVLKSNNFTHKSD---------IWS------------FGFILLKMIDKSLNNIPD-------------------------------DLPTEQFDFLHSC
|...|  ..  .           .||            |. .  | . .   ..|.                               ... . .|.|  .
PNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKM

LATNLSDRLDAQTLLHHPFI
|  . ..|. |.  | ||..
LQYDPDKRITAEQALQHPYF
Kinase DDB0229334.AA CAMK 174-199 23 2.8e-05 12.21 In-house 400-425 (425) Show / Hide 
Range on Protein: 174-199
Range on HMM: 400-425/425
Sequence Identity: 23% (6 aa)

DFLHSCLATNLSDRLDAQTLLHHPFI
|.. ..| .. ..|. ..  | ||..
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase DDB0229334.AA Pkinase 174-199 34 0.000301 16.1 Pfam 268-293 (293) Show / Hide 
Range on Protein: 174-199
Range on HMM: 268-293/293
Sequence Identity: 34% (9 aa)

DFLHSCLATNLSDRLDAQTLLHHPFI
||. .||. . ..|. |. .|.||..
DFIKWCLCKDPKKRPTAEQILQHPWF
Kinase DDB0229334.AA PAKA 60-98 24 0.000597 9.93 In-house 89-129 (260) Show / Hide 
Range on Protein: 60-98
Range on HMM: 89-129/260
Sequence Identity: 24% (10 aa)

IDKFD--NNNFFSQEVIREICEQILLALRFMDNHQIVHRDL
|....  . |... . |  .|...| .| |. .....|||.
ITQCCNIQCNYMDEGQIAYVCRECLQGLEFIHSKHRIHRDI
Kinase DDB0229334.AA PAKA 131-158 39 0.002031 8.04 In-house 171-198 (260) Show / Hide 
Range on Protein: 131-158
Range on HMM: 171-198/260
Sequence Identity: 39% (11 aa)

SPEVLKSNNFTHKSDIWSFGFILLKMID
.|||.. ..  .| |||| | ... ||.
APEVIRRKQYDEKVDIWSLGIMAIEMIE
Kinase DDB0229334.AA CAMKL 163-199 18 0.020034 3.38 In-house 262-297 (297) Show / Hide 
Range on Protein: 163-199
Range on HMM: 262-297/297
Sequence Identity: 18% (7 aa)

NIPDDLPTEQFDFLHSCLATNLSDRLDAQTLLHHPFI
.|. ... .  |.... | .| ..|  .. .. ||. 
PIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM