Gene DDB0229345 (Slime mold)

DDB0229345

Species: Slime mold
Alias: DdisK101, DDB0229345
External Links: DictyBase Link ,
Annotation:

Classification

Group: Other
Family: NEK
Subfamily: NEK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
DDB0229345.AA Protein None 485 None Fasta, JSON
DDB0229345.kin_dom Protein Kinase Domain None 272 None Fasta, JSON

Protein domain

Protein domains of DDB0229345.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0229345.AA NEK1 12-283 48 4.7e-192 644.31 In-house 1-276 (276) Show / Hide 
Range on Protein: 12-283
Range on HMM: 1-276/276
Sequence Identity: 48% (135 aa)

YLIKSQIGSGSYGNTFKVTHKESGQVFCKKSIQVNNQ--ENIEKVLEEGKILTVMDHVNVVKLNDSFFENGN--YVIIMEFAENGDLFQKIENQKRSGKP
|....|||.||.|....|.|||.||....|.|.|...  ...|....|..||..|.|.|.||...||.|||.  ..|.||....|||.|||..|||.||.
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGKL

FSDFEIMHYFCQLVIALNYIHSQNIIHRDIKPKNIVLSSSDSGSGSGSGSGSSNDSIPLLKIADFGVSKLMSETDLYANTTAGTPQYVSYEICNKKPYTN
||...|||.|||...|||.||...|.|||||..||.|..|..|.|||||||||||||||.|..|||.......|..||.|..|||.|.|.|||..|||.|
FSEDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEICQNKPYNN

KTDIWSLGVVLYELMTLSLPFDGRKETVMRNIQTESTIFKPVNHPNEELSSLLFKLLNKNPESRFSTQQILEQVFI
|.||||||.|||||.||..||...............|......|...||.||.......||..|.|..||||..||
KSDIWSLGCVLYELCTLKHPFEANNWKNLVLKICQGTYPPIPPHYSYELQSLVSQMFKRNPRHRPSVNQILERPFI
Kinase DDB0229345.AA NEK 12-283 36 1.2e-115 390.45 In-house 1-286 (286) Show / Hide 
Range on Protein: 12-283
Range on HMM: 1-286/286
Sequence Identity: 36% (110 aa)

YLIKSQIGSGSYGNTFKVTHKESGQV-----FCKKSIQVNN--QENIEKVL-EEGKILTVMDHVNVVKLNDSFFENG--NYVIIMEFAE-NGDLFQK---
| |  .||.||.|  .|| .|. |..     .. | |...|  ... .. . .| .||  ..| |.||  |||.|..     |.||..| .|||.||   
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

IENQKRSGKPFSDFEIMHYFCQLVIALNYIHSQ-----NIIHRDIKPKNIVLSSSDSGSGSGSGSGSSNDSIPLLKIADFGVSKLMSETDLYANT-TAGT
|..|| .||.|.  .|...|.|...||.|.|..     .|.||||||.|| |.......             ...|| |||.||... |  .|.|   ||
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDY-------------HNVKIGDFGISKVLNHTTDMAYTTQVGT

PQYVSYEICNKKPYTNKTDIWSLGVVLYELMTL--SLPFDGR--KETVMR-NIQTESTIFKPVN-H--PNEELSSLLFKLLNKNPESRFSTQQILEQVFI
| | | |.|. |||.|| ||||||.||||..||    ||..          .|. .   ..|.. |    ..|..|. ..|.|.||.| |..||||. ||
PYYMSPEVCQNKPYNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKG-PQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase DDB0229345.AA S_TKc 12-283 28 1.6e-80 274.7 SMART 1-231 (231) Show / Hide 
Range on Protein: 12-283
Range on HMM: 1-231/231
Sequence Identity: 28% (81 aa)

YLIKSQIGSGSYGNTFKVTHKESGQVFCKKSIQVNNQENIEKVLEEGKILTVMDHVNVVKLNDSFFENGNYVIIMEFAEN--GDLFQKIENQKRSGKP--
| |  .||.|..|  .|..||..|...  | |        |... | .||   .| |.||| |.| . ... ..||....  ||||. |....| |..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

FSDFEIMHYFCQLVIALNYIHSQNIIHRDIKPKNIVLSSSDSGSGSGSGSGSSNDSIPLLKIADFGVSKLMSETDLYANTTAGTPQYVSYEICNKKPYTN
|.  .. .|..|.. ||.|.||..|||||.|| || |..                    .||.|||.....       .|  ||| |.. |..   .|. 
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------------------HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGK

-KTDIWSLGVVLYELMTLSLPFDGRKETVMRNIQTESTIFKPVNHPNEELSSLLFKLLNKNPESRFSTQQILE-------QVFI
 | |.||.|..|||...   ||.   ......|              .|. ... |.|.|.|| | .  ..|.         ..
CKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DDB0229345.AA Pkinase 12-283 26 3.5e-72 250.92 Pfam 1-293 (293) Show / Hide 
Range on Protein: 12-283
Range on HMM: 1-293/293
Sequence Identity: 26% (83 aa)

YLIKSQIGSGSYGNTFKVTHKESGQVFCKKSIQVNNQENIEKVLE----EGKILTVMDHVNVVKLNDSFFENGNYVIIMEFAENG----DLFQKIENQKR
| |...|||||.|  .| .|| .|.... | | . ...  ...      | .|.  ..| |.|.| |.| ..... ..||..|.|    |||  |.   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--W

SGKPF--SDFEIMHYFCQLVIALNYIHSQNIIHRDIKPKNIVLSSSDSGSGSGSGSGSSNDSIPLLKIADFGVSKLM-SETDLYANTTAGTPQYVSYEIC
....|  |. |. .|. |.. .|.|.||..|||||.|| || .. ..   ..             .||.|||..|..    .  ..| .||| |.. |..
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDA------------CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVI

N-KKPYTNKTDIWSLGVVLYELMTLSLPFDGR-------KETVMRNIQTESTIFKPVNHPN-------------------EELSSLLFKLLNKNPESRFS
.  ..|. | |.||.|..|||...  .||.|.       .  ....|    . |   .  .                   ||. ... ..|.|.|..| .
RGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT

TQQILEQVFI
 .|||.  ..
AEQILQHPWF
Kinase DDB0229345.AA CAMK 17-283 18 8.8e-71 227.08 In-house 1-425 (425) Show / Hide 
Range on Protein: 17-283
Range on HMM: 1-425/425
Sequence Identity: 18% (80 aa)

QIGSGSYGNTFKVTHKESG------------QVFCKKSIQVN----------------------------NQENIEKVLEEGKILTV-------MDHVNV
..|.||.|  ....||...            | .  | |  .                            .... ..|. | .|.         .|| |.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLNDSFFENGN-------------------YVIIM---EFAENG----DLFQKIENQKRSG-----------KPFSDFEIMHYFCQLVIALNYIHSQNI
.|| . .  . .                   ....|   |....|    |||..|  ... |           . |.  |  .|| |.. |..|.||.||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDIKPKNIVLSSSDSGSGSGSGSGSSND----SIPL-LKIADFGVSKLMSE-----------------------TDLYANTTAGTPQYVS-YEICNK-
.|||.|| || |......| . .     .|    .    .||.||| .. . .                       ..   .|  ||| |..  |. |. 
VHRDLKPENILLDDNNDDSDP-V---E-HDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGK

-------------KPYTNKTDIWSLGVVLYELMTLSLPFDGR---------------KETVMRNIQTE-STIFKPVNHPN--------------------
             ..|. |.|.||.||.|| . .  .||.|                .|.  . .. . . . ... ..                     
GHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVS

EELSSLLFKLLNKNPESRFSTQQILEQVFI
.|  .|. |.|...|| |.. .|.|.  ..
QECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase DDB0229345.AA Ciliate-E2 12-283 23 1.4e-69 237.45 In-house 1-365 (365) Show / Hide 
Range on Protein: 12-283
Range on HMM: 1-365/365
Sequence Identity: 23% (93 aa)

YLIKSQIGSGSYGNTFKVTH-----------------------KESGQVFCKKSIQVNNQENIEK---VL----------EEGKILTVMDHVNVVKLNDS
| .  .||.|..|  .|...                       |  .. . .|... |. |.|..   ..          .| .||  ..| |..|. ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FF--ENGNYVIIMEFAENGDLFQKIENQKRSG-------KPFSDFEIMHYFCQLV---------------IALNYIHSQN-IIHRDIKPKNIVLSSSDSG
|    . |. ..||... ||||. |.|.| .        |.|...|| ... |..                ||.|.||.| |||||||| ||..      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

SGSGSGSGSSNDSIPLLKIADFGVSK----------------LMSETD----------------LYANTTAGTPQYVSYEICNKKP---------YTNKT
                .||.||| ||                .. .                    .||..||| |.. || |.|.         |. | 
----------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKC

DIWSLGVVLYELMTLSLPFDGRKETVMRNIQT-ESTIFKP---------------VNHPNEELSSLLFK----LLNKNPESRFS-TQQILEQVFI
|||||||.|||...  .||       ...|.  .  ...|                ..  .|   |. |    .|.|.|| |..  .|||.  ..
DIWSLGVILYEMLFGKPPF-------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase DDB0229345.AA AGC 12-283 18 5.5e-67 171.28 In-house 1-395 (395) Show / Hide 
Range on Protein: 12-283
Range on HMM: 1-395/395
Sequence Identity: 18% (78 aa)

YLIKSQIGSGSYGNTFKVTHK------ESGQVFCKKSIQVNN---QEN---IEKVLEE------------GKILTVMD----------HVNVVK-LNDSF
. ..  || ||.|  . | .|       .|...  | ..      . .   .|... |             .||. ..          | ..|| |  ||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

FENGN--YVIIMEFAE--------NGDLFQKIENQKR-SGKPFSDFEIMHYFCQ-------LVIALNYIHS-QNIIHRD-IKPKNIVLSSSDSGSGSGSG
  . .    ..||...         |..   . .|.|   . |.  .. .|...       .| || |.|| ..||||| .|| ||.| .          
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDED---------

SGSSNDSIPLLKIADFGVSKLMSETD--------------------------------------------------LYANTTAG--TPQYVSYEICNKKP
          .|..||| .| .   .                                                    ..|  |  ||.|.. ||     
--------GHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----

YTNKTDIWS--LGVVLYELMTLSLPFDGR-----------KETVMRNIQ------TESTIFK--------PVNHPNEELSSLLFKLLNKNPESRFS----
|.   |.||  ||...||..|   || |            .. .. .|.      ..   |         .. .  .|. .|. |||.|.|| |      
YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGN

------TQQILEQVFI
      ...| .  . 
DFGDKGAEEIKNHPWF
Kinase DDB0229345.AA CAMKL 12-283 26 4.9e-63 199.94 In-house 1-297 (297) Show / Hide 
Range on Protein: 12-283
Range on HMM: 1-297/297
Sequence Identity: 26% (83 aa)

YLIKSQIGSGSYGNTFKVTH-KESGQVFCKKSIQVNNQENIEKVLE---------------EGKILTVMD---HVNVVKLNDSFFENGN------YVIIM
| |  ..| ||.|     || .  |.    | |  .   |.....                | .|.  ..   | |..|| . .    .      ....|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EFAENGD--LFQKIENQKRSGKPFSDFEIMHYFCQLVIALNYIHSQNIIHRDIKPKNIVLSSSD-SGSGSGSGSGSSNDSIPLLKIADFGVSKLMSE---
| ...|.  ||..|..... .....  |  .||.|.| |.||.||..|.|||||| || |.... .                 .||.||| | .. .   
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN----------------NIKIIDFGFSNMYRPCIF

-TDLYANTTAGTPQYVSYEICNK--KPYT-NKTDIWSLGVVLYELMTLSLPFDGR---------KETVMRNIQTESTIFKPVNHPNEELSSLLFKLLNKN
 ..   .|  |.| | . ||...  |||   |.||||.||.|| ...  ||||.          . . .. | .  . . . .|.  .. .|. |.|..|
GPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVN

PESRFSTQQILEQVFI
|| |.. .||..  . 
PEKRPTIHQIMNHPWM
Kinase DDB0229345.AA Ciliate-E2-Unclassified 12-283 24 5.3e-62 212.31 In-house 1-352 (352) Show / Hide 
Range on Protein: 12-283
Range on HMM: 1-352/352
Sequence Identity: 24% (90 aa)

YLIKSQIGSGSYGNTFKVTHKESGQVF----CKKSIQVNNQENIEKV---------LEEGK-------------ILTVMDHVNVVKLNDSFFENGNYVII
| |  |||.|..|  .|. ||. .  .     .|.||...| .|...         ... |             ||  ..| ..||. . |    |  |.
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEFAENGDLFQKIE-------------NQKRSGKPFSDFEIM-----HYFCQLVIALNYIHSQN-IIHRDIKPKNIVLSSSDSGSGSGSGSGSSNDSIPL
||..|.|||.| |.             ......| |.....      .|| |.. .|.|.|..| |||||||| ||..... .                 
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK--------------NYY

LKIADFGVSK---LMSETDLY-------------ANTTAGTPQYV----SYEICNKKPYTNK----TDIWSLGVVLYELMTLSLPFDGRKETV-------
.||.||| ||    ... | .             ..|..|||.|     . |.  .. | ..     |||||||.|||...  .||......        
IKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQ

---------MRNIQTESTIFKPVNHP-------NEELSSLLF----KLLNKNPESRFSTQQILEQVFI
         ..... .  |..|   .       ..|   ..     |.|.|||..| . .|||.  ..
WINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase DDB0229345.AA STE 12-283 22 9.2e-59 201.54 In-house 1-359 (359) Show / Hide 
Range on Protein: 12-283
Range on HMM: 1-359/359
Sequence Identity: 22% (85 aa)

YLIKSQIGSGSYGNTFKVTHK------ESGQV---------FCKKSIQVNNQ-----------------ENIEKVLEEGKILTVMD--HVNVVKLNDSFF
. . ..||.|..| ..|  ..      ..|.|         .  | . ..|.                 |.....|.| ||.  ..  | |.||  ...|
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

ENG-------NYVIIMEFAENGDLFQKIENQKRSGKPFS----------DFEIMHYFCQLVIA-LNYIHSQNIIHRDIKPKNIVLSSSDSGSGSGSGSGS
 .|       .  |.||. ..| | . |.. .  |||..            .| .. .|.. . |.|.||..|||||||| || |               
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL---------------

SNDSIPLLKIADFGVSKLMSE---------------TDL-YANTTAGTPQYVSYEICNK------KPYTNKTDIWSLGVVLYELMTLSLPF-DGRKETVM
        |..||||.. ...               |     || .||| . . |. ..      |.|. | |||||| .. |. |   |. |.    .|
-------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAM

RNIQTESTIF-----------KPVNHPN----------------------EELSSLLFKLLNKNPESRFSTQQILE--QVFI
 .|.... ..           .|   |.                      .|.   . | |.|.|. | ...| |.    ||
FMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase DDB0229345.AA ULK 12-283 24 2.1e-58 200.32 In-house 1-329 (329) Show / Hide 
Range on Protein: 12-283
Range on HMM: 1-329/329
Sequence Identity: 24% (84 aa)

YLIKSQIGSGSYGNTFKVTHKESG-----QVFCKKSI---QVNNQEN------IEKVLEEGKILTVMD--------HVNVVKLNDSFFEN--GNYVIIME
| .. ..|.||.|  .| ..|...     .|.||.     . ... .      .. .  | ||.  ..        | |.||| | | .    |. ||||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FAENGDLFQKIENQKR------SGKPFSDFEIMHYFCQLVIALNYIHSQNIIHRDIKPKNIVLSSS----DSGSGSGSGSGSSNDSIPLLKIADFGVSKL
. . |||.| |...|.       .| .|  |. ..|.|.. .. ..|..||||||||| || ..      ||         . .  .. ||||||| .| 
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSK------K-V-HP-NGVLKIADFGFAKH

MSET--DLY-ANTTA------GTPQYVSYEICN----KKPYTNK-TDIWSLGVVLYELMTLSLPFDGR-KETV----MRN----------IQTESTIFK-
...   .   . |.       ||| | . .| .    .|||... .||||||...||. .   || .   ...    ...          |... . |. 
VDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPK

--PVNHPNEELSSLLFKLLNKNPESRFSTQQILEQVFI
  . ..  .|. .|. ..| .... |.| .....  ..
DGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase DDB0229345.AA ULK 12-283 25 1.5e-57 197.5 In-house 1-324 (324) Show / Hide 
Range on Protein: 12-283
Range on HMM: 1-324/324
Sequence Identity: 25% (86 aa)

YLIKSQIGSGSYG-NTFKVTHKES---GQVFCKKSIQ---VNNQEN-------IEKVLEEGKILTVMD---HVN--VVKLNDSFFEN--GNYVIIMEFAE
| .. ..|.||.|   .| ..|..   .|..  | |.    |...|       ...   | .|.  ..   |.|  .||| | | .    |. ||||. .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGDLFQKIENQKR-----SGKPFSDFEIMHYFCQLVIALNYIHSQNIIHRDIKPKNIVLSSS----DSGSGSGSGSGSSNDSIPLLKIADFGVSKLMSET
 |||.| |...|.      .| .|  |. ..| |.. .. ..|..||||||||| || ..      ||         . .  .. ||||||| .|   . 
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSK------K-V-HP-NGVLKIADFGFAKHVDNN

DL---YANTTA------GTPQYVSYEICN----KKPYTNK-TDIWSLGVVLYELMTLSLPFDGR-KETV-------------MRNIQTESTIFK---PVN
..      |.       ||| | . .| .    .|||... .||||||...||. . . || ..  ...             .  |...   |.   . .
NMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDP

HPNEELSSLLFKLLNKNPESRFSTQQILEQVFI
.  .|. .|. ..| .... |.| ..|..  ..
KISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase DDB0229345.AA TyrKc 12-281 20 6.4e-17 50.82 SMART 1-280 (280) Show / Hide 
Range on Protein: 12-281
Range on HMM: 1-280/280
Sequence Identity: 20% (62 aa)

YLIKSQIGSGSYGNTFKVTHKESGQVFCKKSIQVNNQENIEKVLEEGKILTVM--DHVNVVKLNDSFFEN-------GNYVIIMEFAENGDLFQKIENQK
   . ..|.| .|  .| | |   ||  |.         .|  ..| .|..    .| |.|.|     .        . . |.||....||| . . . .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

RSGKPFSDFEIMHYFCQLVIALNYIHSQNIIHRDIKPKNIVLSSSDSGSGSGSGSGSSNDSIPLLKIADFGVSKLMSET-------DLYA-----NTTA-
.    ..  .  ..  |     .|.||.|.||||.   |. ...                     ||.||| |.   .        | |      .. . 
PK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----------------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTM

GTPQYVSYEICNKKPYTNKTDIWSLGVVLYELMTL-SLPFDG------RKETVMRNIQTESTIFKPVN-------HPNEELSSLLFKLLNKNPESRFSTQ
      . |  |.. .| |.|.|| ||...|..|.   |  |        . |......     .| |       .  .|. ..  .  . .||.| . .
LPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFS

QILEQV
.| |. 
EIHECF
Kinase DDB0229345.AA Pkinase_Tyr 12-184 21 1.6e-09 32.87 Pfam 1-167 (270) Show / Hide 
Range on Protein: 12-184
Range on HMM: 1-167/270
Sequence Identity: 21% (40 aa)

YLIKSQIGSGSYGNTFKVTHK-----ESGQVFCKKSIQVNNQEN--IEKVLEEGKILTVM-DHVNVVKLNDSFF-ENGN--YVIIMEFAENGDLFQKIEN
  .  ..|.|..|. .| | |     .  .|  |.  .   .|.  .|. ..| ||.. . .| |.|.|      . .   . |.||....|||     .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

QKRSGKPFSDFEIMHYFCQLVIALNYIHSQNIIHRDIKPKNIVLSSSDSGSGSGSGSGSSNDSIPLLKIADFGVSKLMSETDLY
.. ...|..  .. ..  |   ...| .|.|.||||.  .|. ...                .    ||.||| .... ..| |
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE----------------NN-VVKICDFGLARDIYNDDYY
Kinase DDB0229345.AA Pkinase_Tyr 205-224 45 0.000144 16.09 Pfam 191-210 (270) Show / Hide 
Range on Protein: 205-224
Range on HMM: 191-210/270
Sequence Identity: 45% (9 aa)

YTNKTDIWSLGVVLYELMTL
.| |.|.|| ||...|..|.
FTTKSDVWSFGVLMWEIFTY