Gene DDB0231198 (Slime mold)

DDB0231198

Species: Slime mold
Alias: DdisK112, DDB0231198
External Links: DictyBase Link ,
Annotation:

Classification

Group: Other
Family: Other-Unique

Sequence

Name Sequence Type Origin Length Description Download
DDB0231198.AA Protein None 1212 None Fasta, JSON
DDB0231198.kin_dom Protein Kinase Domain None 224 None Fasta, JSON

Protein domain

Protein domains of DDB0231198.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0231198.AA Other-Unique 961-1175 10 2.4e-29 96.89 In-house 1-249 (249) Show / Hide 
Range on Protein: 961-1175
Range on HMM: 1-249/249
Sequence Identity: 10% (28 aa)

VDKLKRLQFSDYIIKMPAISDDNPNKRGMLLECATAGSLKTN--------------------------LLEYRSWKLVIRFMMDICLGMIDIHKCQIIHR
 ... . .... ....  ... ...|  . . .  . ....|                          ..|........ .....  .... ..||. | 
IKDIGKGTYGRVYKQHHNKKKKYCAKKTKHHKI-HCMDMDNNKREQIYHYQIIHCIFYWTMNHCHLCFCYEHCPNMIFYIMYPWY--HHHCECQCQCEHW

DLKPDNILVFENFNSSEASDENDERQREFGGLICKITDLG-----------------ASIQKELVHDNNFTSTFHTDDYVPEEYGRFQYDGEKVDIYSFG
.   ..|....... ...  .. . .  . . ...... .                  ..... . ...| . | .......|. . ...||| |.|.||
MNCCHMIHNLHHLHNNNHIHCDINPNNIWINQNNIHMCHNCGHNIPTIIIEHQHIKIMDFNNN-N-MMYFAPEF-SCRWCSPETFDYWPLGEKIDQYHFG

CTFFEMVTKHRYQYKHPTPLHRDFLTTDFQYIPIRIKTLIASLLAEQSQRKQSFNEVY
|..|.|...|.... | . .|.. .... ..  |.|. ..  . .  ....|..| .|
CYHFHMNCQHWIFHYHDV-QHWPPHESPKDI-HILICQCECCHQCM-VNPYQNPNCFY
Kinase DDB0231198.AA TKL 997-1134 26 1.9e-22 77.68 In-house 123-293 (364) Show / Hide 
Range on Protein: 997-1134
Range on HMM: 123-293/364
Sequence Identity: 26% (49 aa)

GSLKTNLLEYRSWKLVIRFMMDICLGMIDIHKCQ--------IIHRDLKPDNILVFENFN--SSEASDENDERQREFGGLICKITDLGASIQKELVHDNN
|||  .|.    | . .|...||..||   | ..        |||||||..||||.||..  | . .       ..     |||.|.| |  ..   ..|
GSLLHYLH----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVS-NYM------YNPNADWCCKICDFGLSRFMSQSGNMN

FTS------------------TFHTDDYVPEEY-----------------GRFQYDGEKVDIYSFGCTFFEMVTKHRYQYKHP
 |.                     |  . . |                  . |.|. ||.|.||||  ..|..|  |  |..|
DTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYS-EKCDVYSFGIVLWEILTRCRPYYDYP
Kinase DDB0231198.AA Ciliate-E2 1019-1126 20 9e-19 61.06 In-house 169-292 (365) Show / Hide 
Range on Protein: 1019-1126
Range on HMM: 169-292/365
Sequence Identity: 20% (30 aa)

ICLGMIDIHKCQ-IIHRDLKPDNILVFENFNSSEASDENDERQREFGGLICKITDLGASI--------------QKELVHDN---NFTSTFH--------
|.|..  .|.   |||||.||.|||.                        .||.|.| |               .|..   .   . |..          
IILALEYLHSKNNIIHRDIKPENILF------------------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNM

------TDDYVPEEYGR---------FQYDGEKVDIYSFGCTFFEMVTK
      |  |.. |  .         ... ..|.||.|.|....||...
FNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG
Kinase DDB0231198.AA Ciliate-E2-Unclassified 1019-1125 24 1.6e-17 57.38 In-house 152-265 (352) Show / Hide 
Range on Protein: 1019-1125
Range on HMM: 152-265/352
Sequence Identity: 24% (32 aa)

ICLGMIDIHKCQ-IIHRDLKPDNILVFENFNSSEASDENDERQREFGGLICKITDLGASI--------------QKELVHDNNFTSTFHTDDYV-----P
|..|   .|. . |||||.||.|||. .| .                 . .||.|.| |.              ..    .......  |  |      |
ILQGLEYLHHKNNIIHRDIKPENILFDNNGK----------------NYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAP

EEYGRFQYDG---EKVDIYSFGCTFFEMVT
| ... .||.   .|.||.|.|. ..||..
EVLQGQNYDHSKAYKCDIWSLGVILYEMLF
Kinase DDB0231198.AA Pkinase 964-1127 27 1.9e-16 59.21 Pfam 54-209 (293) Show / Hide 
Range on Protein: 964-1127
Range on HMM: 54-209/293
Sequence Identity: 27% (48 aa)

LKRLQFSDYIIKMPAISDDNPNKRGMLLECATAG----SLKTNLLE-------YRSWKLVIRFMMDICLGMIDIHKCQIIHRDLKPDNILVFENFNSSEA
.|||. ...|...  .  | ...  | .|..  |    .|.  ...       | |.. ....|  |. |.  .|.. ||||||||.|||. .| . .. 
MKRLN-HPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLF-DYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-

SDENDERQREFGGLICKITDLGASIQKELVHDNNFTSTFHTDDYV-PEEYGRFQYDGEKVDIYSFGCTFFEMVTKH
              . ||.| | . |... ..  .|.   | .|. ||     ||.| |||..|.||...||....
--------------CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGR
S_TKc DDB0231198.AA S_TKc 865-1182 15 1.1e-13 23.83 SMART 1-231 (231) Show / Hide 
Range on Protein: 865-1182
Range on HMM: 1-231/231
Sequence Identity: 15% (52 aa)

ETEIEPFASGGQANIYMVKHIDWPMLSNCPEGSYVFKQFIETKDSLQLEEDIEREMYEEKIYQTYKTGESVDNFKYNFSNVEQTDKKSLETLFYEEVDKL
 . ...  .|. .  | ..|..           .  |.                                                      .. |.. |
YEILRKIGKGAFGKVYKCRHKK-------TGRIVAIKIIK--------------------------------------------------EHIRREIQIL

KRLQFSDYIIKMPAISDDNPNKRGMLLECATA--GSLKTNLLEY--------RSWKLVIRFMMDICLGMIDIHKCQIIHRDLKPDNILVFENFNSSEASD
|.    ..|.|.  . .|  ..  | .|..    |.|.. . ..         .   . ..|  ||...  .|. .||||||||.|||. |         
KK--HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---------

ENDERQREFGGLICKITDLGASIQKELVHDNNFTSTFHTDDYV-PEEYGRFQYDGEKVDIYSFGCTFFEMVTKHR-YQYKHPTPLHRDFLTTDFQYIPIR
              ||.| | . |         |.   | .|. ||     .|...|.|..|.||...||..    ..  ..  . .  .       .  
------------HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-------SPE

IKTLIASLLA-EQSQRKQSFNEVY----NDLQDIY
 | .|  .|  . ..|              .    
AKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DDB0231198.AA AGC 1026-1125 19 3e-13 29.12 In-house 169-300 (395) Show / Hide 
Range on Protein: 1026-1125
Range on HMM: 169-300/395
Sequence Identity: 19% (31 aa)

IHK-CQIIHRD-LKPDNILVFENFNSSEASDENDERQREFGGLICKITDLGASIQ---------------------------------------------
.|.   ||||| |||.|||  |.                     .|.|| | . .                                             
LHSHMGIIHRDYLKPENILLDED-------------------GHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMS

----KELVHDNNFTSTFH---TDDYVPEEYGRFQYDGEKVDIYS--FGCTFFEMVT
        .... |.||    | .|.. |       |  .|..|  .|| ..||.|
QEDDTTR-KKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMYEMLT
Kinase DDB0231198.AA Dicty4 1008-1048 39 1.1e-11 35.41 In-house 107-152 (277) Show / Hide 
Range on Protein: 1008-1048
Range on HMM: 107-152/277
Sequence Identity: 39% (18 aa)

SWKLVIR---FMMDICLGMIDIHK--CQIIHRDLKPDNILVFENFN
.| |..|    . |. .||.  |   . |||||||..|.|| .|..
DWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWR
Kinase DDB0231198.AA ULK 1010-1074 30 1.3e-11 36.92 In-house 130-187 (329) Show / Hide 
Range on Protein: 1010-1074
Range on HMM: 130-187/329
Sequence Identity: 30% (21 aa)

KLVIRFMMDICLGMIDIHKCQIIHRDLKPDNILVFENF---NSSEASDENDERQREFGGLICKITDLG
. .| |...|. |. ..|| .|||||.||.|||. ...   .|        .    .   ..||.| |
QEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSK-------K-V-HP-NGVLKIADFG
Kinase DDB0231198.AA TKL-Unique 957-1048 27 1.4e-11 37.29 In-house 136-249 (290) Show / Hide 
Range on Protein: 957-1048
Range on HMM: 136-249/290
Sequence Identity: 27% (31 aa)

FYEEVDKLKRLQFSDYIIKMPAISDD---NPNKRGMLLECATAGSLKTNLL------------EYRSWKLVIRFMMDICLGMIDIHKCQ--IIHRDLKPD
|..||  .|.|.... | .  ... |    |... . .|.   |||  .|                ........  || .||. .| |.  |||||||. 
FENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSS

NILVFEN-----FN
|.|| .|     .|
NFLVDNNSNIAEWN
Kinase DDB0231198.AA ULK 1010-1074 32 1.4e-11 37.37 In-house 126-183 (324) Show / Hide 
Range on Protein: 1010-1074
Range on HMM: 126-183/324
Sequence Identity: 32% (22 aa)

KLVIRFMMDICLGMIDIHKCQIIHRDLKPDNILVFENF---NSSEASDENDERQREFGGLICKITDLG
. .| |...|| |. ..|| .|||||.||.|||. ...   .|        .    .   ..||.| |
QEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSK-------K-V-HP-NGVLKIADFG
Kinase DDB0231198.AA STE 1010-1078 24 5.9e-10 31.47 In-house 151-196 (359) Show / Hide 
Range on Protein: 1010-1078
Range on HMM: 151-196/359
Sequence Identity: 24% (17 aa)

KLVIRFMMDICLG-MIDIHKCQIIHRDLKPDNILVFENFNSSEASDENDERQREFGGLICKITDLGASIQ
......  .|. | .  .|. .|||||.||.|||.                        .|..| | . |
SQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL------------------------VKLCDFGVCGQ
TyrKc DDB0231198.AA TyrKc 910-1178 16 1.1e-08 -82.43 SMART 1-280 (280) Show / Hide 
Range on Protein: 910-1178
Range on HMM: 1-280/280
Sequence Identity: 16% (52 aa)

LQLEEDIER----EMYEEKIYQTYKTGESVDNFKYNFSNVE------QTDKKSLETLFYEEVDKLKRL-QFSDYIIKMPAISDDNP------NKRGMLLE
..|.. . .    | |. . .                  ..      . |.   .  |..|   ...|    . |... ..  .            ...|
ITLGKKLGEGAFGEVYKGTWK------------------IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVME

CATAGSLKTNLLEYR---SWKLVIRFMMDICLGMIDIHKCQIIHRDLKPDNILVFENFNSSEASDENDERQREFGGLICKITDLGASIQKELV-HDNNFT
 .  |.||  | ..|   ..|  . |. .|. ||  .|. ..|||||   |.|| ||.                   ..||.| | |   .   .     
YMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-------------------TVKISDFGLSRDIYDDDQQG---

STFHTDDYVPEE--YGR------------FQYD--GEKVDIYSFGCTFFEMVTKHRYQYKH-----PTPLH-RDFLTTD-----FQY--------IPIRI
    .| |.. |   |.            ..|    .| |..||| . .|. |     |        .. . . .. .       ..         |  .
--ESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEM

KTLIASLLAEQSQRKQSFNEVYNDL
 ... .  .|.     .|.|.. ..
YQIMKQCWHEDPEDRPTFSEIHECF
Kinase DDB0231198.AA STE 1108-1125 55 5.8e-05 13.61 In-house 246-263 (359) Show / Hide 
Range on Protein: 1108-1125
Range on HMM: 246-263/359
Sequence Identity: 55% (10 aa)

GEKVDIYSFGCTFFEMVT
..|.||.|.|||  ||.|
DTKCDIWSLGCTIIEMAT
Kinase DDB0231198.AA ULK 1110-1125 56 0.000403 10.59 In-house 232-247 (324) Show / Hide 
Range on Protein: 1110-1125
Range on HMM: 232-247/324
Sequence Identity: 56% (9 aa)

KVDIYSFGCTFFEMVT
|.||.|.|| |.||..
KCDIWSLGCIFYEMLY
Kinase DDB0231198.AA ULK 1110-1125 56 0.000417 10.33 In-house 236-251 (329) Show / Hide 
Range on Protein: 1110-1125
Range on HMM: 236-251/329
Sequence Identity: 56% (9 aa)

KVDIYSFGCTFFEMVT
|.||.|.|| |.||..
KCDIWSLGCIFYEMLY
Kinase DDB0231198.AA TKL-Unique 1098-1134 40 0.001094 9.09 In-house 195-233 (290) Show / Hide 
Range on Protein: 1098-1134
Range on HMM: 195-233/290
Sequence Identity: 40% (16 aa)

PEEYGR--FQYDGEKVDIYSFGCTFFEMVTKHR-YQYKHP
||.  .  .||. ||.|.||||    |..| ..   || |
PEVLRMNFCQYS-EKSDVYSFGIVLWEIATRKITKTYKKP
Kinase DDB0231198.AA Dicty4 1109-1126 50 0.068018 2.3 In-house 196-213 (277) Show / Hide 
Range on Protein: 1109-1126
Range on HMM: 196-213/277
Sequence Identity: 50% (9 aa)

EKVDIYSFGCTFFEMVTK
||.| ||||   .|..|.
EKADVYSFGIVLWEILTR