Gene TtkA (Slime mold)

TtkA

Species: Slime mold
Alias: DdisK133, DDB0220499, TtkA, DdMps1, mps1
External Links: DictyBase Link ,
Annotation:

Classification

Group: Other
Family: TTK

Sequence

Name Sequence Type Origin Length Description Download
TtkA.AA Protein None 983 None Fasta, JSON
TtkA.kin_dom Protein Kinase Domain None 268 None Fasta, JSON

Protein domain

Protein domains of TtkA.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase TtkA.AA TTK 714-981 47 9.60000000001e-208 693.91 In-house 1-344 (344) Show / Hide 
Range on Protein: 714-981
Range on HMM: 1-344/344
Sequence Identity: 47% (162 aa)

YLRIEFIGKGGSGKVYKVLSG-DLKIYALKYVCLS--DPNEIEAQLNEIEMLKRLRKQV-NIIQLIDYEVNMAKNYILLVLEFGEIDLSKLLQRLQTPNG
|..|..||.|||.||..|||. ..||||||||||.  ||..|....||||||..|..|. .||||.|||..|...||..|.|.|..||.|.||...||..
YSIIKQIGCGGSSKVFQVLSEDSKKIYALKYVCLDFADPQTIQGYMNEIEMLNKLQQQKDCIIQLYDYEMTMEEQYIYMVMECGDCDLNKWLQKYKTPMN

TNVNFIRIYWQQMLQAVHTIHEEKIIHGDLKPANFVSVQGSLKLIDFGIAKAIQSDDTTNIVRESQIGTINYISPEALIDTSQGGPKQCM----------
.|..|...|||||||.||.||...|.|.||||||||.|||.|||||||||.|||.|||||||.||||||.||.||||..|.|.|....||          
LNPWFMWCYWQQMLQCVHVIHQHGIVHSDLKPANFVMVQGMLKLIDFGIANAIQNDDTTNIVKESQIGTFNYMSPEAIQDMSYGNENMCMHHKKPRLKIN

--------------------------------------------------------KLGRASDIWSLGCILYEMAFGYPPFKSFSNIISKYQAIINPHHK
                                                        |....||.||.|||||.|..|..||....|..||..||.|||||
CKSDVWSLGCILYSMVYGRTKFQHIVHRLLKMQAICNPDHFIDFQPIENELLLDVWKISCKSDVWSCGCILYYMIYGKTPFQHIQNQYSKMHAICNPHHK

IEFPVHP------NENLLKVLKLCLIRNPHERPTIPTLLNHDFL
||||.||      |..|..|.|.||.|||..|..||.||||.|.
IEFPEHPPYYEKINKMLIHVMKCCLYRNPKKRWSIPELLNHPFH
Kinase TtkA.AA S_TKc 714-981 26 1.1e-68 235.35 SMART 1-231 (231) Show / Hide 
Range on Protein: 714-981
Range on HMM: 1-231/231
Sequence Identity: 26% (75 aa)

YLRIEFIGKGGSGKVYKVLSGD-LKIYALKYVCLSDPNEIEAQLNEIEMLKRLRKQVNIIQLIDYEVNMAKNYILLVLEFGEI---DLSKLLQRLQTPNG
|  .. ||||. |||||.   .  .|.|.| .        |  ..||..||.  .  ||..|.|. ..   ... .|.|. .    || ..... ... .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---TNVNFIRIYWQQMLQAVHTIHEEKIIHGDLKPANFVSVQGSLKLIDFGIAKAIQSDDTTNIVRESQIGTINYISPEALIDTSQGGPKQCMKLGR-AS
    .   .| | .|...|.  .|. .||| ||||.|    .  .|..|||.|. .           ...|| .|..|| |            . |. ..
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL----------TTFCGTPWYMAPEVL------------GYGKCKC

DIWSLGCILYEMAFGYPPFKSFSNIISKYQAIINPHHKIEFPVHPNENLLKVLKLCLIRNPHERPTIPTLLN-------HDFL
|.||.|||||||. |||||    ..   .. |              . ..  .. || ..| .|||.  .|.       | ..
DWWSCGCILYEMLCGYPPFP---QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase TtkA.AA Pkinase 714-981 26 5.6e-59 207.04 Pfam 1-293 (293) Show / Hide 
Range on Protein: 714-981
Range on HMM: 1-293/293
Sequence Identity: 26% (83 aa)

YLRIEFIGKGGSGKVYK-VLSGDLKIYALKYVCLSDPNEIEAQLN----EIEMLKRLRKQVNIIQLIDYEVNMAKNYILLVLEFGEI-----DLSKLLQ-
| ... ||.|..|.||| .  |. ||.|.| ..... .. . | .    ||...||| .  ||..|.|.  .  |..| .|.|. |      ||. ... 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

RLQTPN--GTNVNFIRIYWQQMLQAVHTIHEEKIIHGDLKPANFVSV-QGSL----KLIDFGIAKAIQSDDTTNIVRESQIGTINYISPEALIDTSQGGP
. ...     ..  .. |. |.|...  .|...||| ||||.|.  . .| .    |..|||.|| ..     |    .  ||..|..|| .        
WRHGCFYFSEWE--CKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIR-------

KQCMKLGRASDIWSLGCILYEMAFGYPPFK------SFSNIISKYQAIINPHHKIEFPVHPN-------------------ENLLKVLKLCLIRNPHERP
  . . |...|.||.|||||||..|.|||.      .  . . ... |  |  . ..|   .                   |......| || ..|..||
-GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRP

TIPTLLNHDFL
|.. .|.|...
TAEQILQHPWF
Kinase TtkA.AA STE 714-981 20 1.2e-53 184.51 In-house 1-359 (359) Show / Hide 
Range on Protein: 714-981
Range on HMM: 1-359/359
Sequence Identity: 20% (76 aa)

YLRIEFIGKGGSGKVYKVLSGD----------------LKIYALKYVCLSDPN-----------------EIEAQLNEIEMLKRLRK-QVNIIQLIDYEV
. .||.||||..|.||| .  .                 .|.| | . |.. |                 |..  |.||...|....   ||.. .....
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

NM-----AKNYILLVLEFGE-IDLSKLLQRLQTPNGTN-----------VNFIRIYWQQMLQA-VHTIHEEKIIHGDLKPANFVSVQGSLKLIDFGIAKA
.      ..... ...|. .   |......   .....            . |... .| |..  . .|. .||| |.||||        ||.|||... 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----VKLCDFGVCGQ

IQSD-------------DTTNIVRESQIGTINYISPEALIDTSQGGPKQCMK-LGRASDIWSLGCILYEMAFGYPPFKSFSNIISKYQAIIN--------
....             .|.   | . .||  . .|| .   .||     .|  .. .||||||| . ||| | ||.  ...    .....|        
LTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-R---DKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFE

-------PHHKIEFPVHPN-----------------ENLLKVLKLCLIRNPHERPTIPTLLN--HDFL
       |. ... ....|                 ...   ...||...|..|||   ||.  | |.
QLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase TtkA.AA AGC 714-981 20 1.2e-51 130.71 In-house 1-395 (395) Show / Hide 
Range on Protein: 714-981
Range on HMM: 1-395/395
Sequence Identity: 20% (83 aa)

YLRIEFIGKGGSGKVYKVLS-------GDLKIYALKYVCLSD------PNEIEAQLNE------------IEMLKRLRK---------QVNIIQ-LIDYE
.  .  ||||. |||| |         .  |.||.| .  ..       |..|  ..|             ..|.....           .|.. |    
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

VNMAKNYILLVLEF-----------GEIDLSKLLQ--RLQTPN--GTNVNFIRIYWQQ-------MLQAVHTIHE-EKIIHGD-LKPANFV-SVQGSLKL
 .  ..|. .|.|.           |  .|   ||  |    .    . . .|.|  .       .. |.. .|.  .||| | ||| | .   .| .||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRR----KEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKL

IDFGIAKAIQSDDTT----------------------------------------------NIVRESQ-IG--TINYISPEALIDTSQGGPKQCMKLGRA
 ||| .| . .|..                                               . .| .   |  | .|..|| |              |.|
TDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-------------YGKA

SDIWS--LGCILYEMAFGYPPFKSFS---------NIISKYQAIINP----HHKIEFP----------VHPNENLLKVLKLCLIRNPHERPT--------
 |.||  |||..||| .||||| . .         |   ..| |.|.    ..|..||          ..  ...   .| .| ..| .|..        
CDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGD

--IPTLLNHDFL
  .  . || . 
KGAEEIKNHPWF
Kinase TtkA.AA Ciliate-E2 714-981 21 4e-41 138.91 In-house 1-365 (365) Show / Hide 
Range on Protein: 714-981
Range on HMM: 1-365/365
Sequence Identity: 21% (83 aa)

YLRIEFIGKGGSGKVYKV---LSG---------------------DLKIYALKYVCLSDPNEIEAQLNEIEMLKRLR------------KQV---NIIQL
|  |. ||.|. |.|||.   . .                     . ||||.|..    .|.||....|| ......            .|.   |||..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIM---KKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKM

IDYEVNMAKNYILLVLEFGEI-DLSKLLQRLQTPNGTN--------VNFIRIYWQQMLQ---------------AVHTIHEEK-IIHGDLKPANFVSVQG
...  .. .|.| ||.|. .  || ....  ..  . .         . |. . .| ||               |.. .|... ||| |.|| | .    
YECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---

SLKLIDFGIAKAIQSDDT--------TNIVRES---------------------QIGTINYISPEALIDTSQGGPKQCMKLGRASDIWSLGCILYEMAFG
 .|.||||..| .. |           ..   .                     ..|| .| .|| |   . .. ..    . ..||||||.||||| ||
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

YPPFKSFSNIISKYQAIINPHHKIEFP----------------VHPNENLLKVLKL----CLIRNPHERPT-IPTLLNHDFL
.|||         .| |..   .. .|                 .  ..    .|     .| ..| .|.| .  .||| ..
KPPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase TtkA.AA ULK 714-981 22 8.3e-41 141.89 In-house 1-324 (324) Show / Hide 
Range on Protein: 714-981
Range on HMM: 1-324/324
Sequence Identity: 22% (76 aa)

YLRIEFIGKGGSG-KVYKVL---SGD-LKIYALKYVC---LSD-PNE------IEAQLNEIEMLKRLR--KQVN--IIQLID-YEVNMAKNYILLVLEFG
|  .. .|||  | ||||     ...  ...| | .    ... .||      .. . |||. .| |   | .|  |..|.| .|     |.| ...|. 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNH-NNIYIIMEYC

EI-DLSKLLQRLQT------PNGTNVNFIRIYWQQMLQAVHTIHEEKIIHGDLKPAN-FVSV------------QGSLKLIDFGIAKAIQSDDTTNIVRE
.  ||...... ..      ..  . . .... .| ...   .|...||| |.||.|  ..             .| ||. ||| || .....    .. 
NGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

SQI------GTINYISPEALIDTSQGGPKQ--CMKLG-RASDIWSLGCILYEMAFGYPPFKS-FSNII----SKYQ-----AIINPHHKIEFP-----VH
..       ||  | .|. | .       |  ... .   .||||||||.||| .|..||.| |.. .    .  .      |.    .|.||     ..
TCVNEKRIKGTPLYMAPQILQG-------QGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPK

PNENLLKVLKLCLIRNPHERPTIPTLLNHDFL
  ...   .. .|.... .| ... ..|| ..
ISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase TtkA.AA ULK 714-981 23 3.8e-40 137.85 In-house 1-329 (329) Show / Hide 
Range on Protein: 714-981
Range on HMM: 1-329/329
Sequence Identity: 23% (79 aa)

YLRIEFIGKGGSGKVYKVL-SGD----LKIYALKYVC----LSDPNE------IEAQLNEIEMLKRLR-------KQVNIIQLID-YEVNMAKNYILLVL
|  .. .|||  |||||     .     ...| | ..      ..||      ..   |||. .|.|        .  ||..|.| .|     |.| ...
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNH-NNIYIIM

EFGEI-DLSKLLQRLQT-------PNGTNVNFIRIYWQQMLQAVHTIHEEKIIHGDLKPAN-FVSV------------QGSLKLIDFGIAKAIQSDDTTN
|. .  ||...... ..       ..  . . .... .| |..   .|...||| |.||.|  ..             .| ||. ||| || ...|   .
EYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQ

IVRESQI------GTINYISPEALIDTSQGGPKQ--CMKLG-RASDIWSLGCILYEMAFGYPPFKS-FSNII-SKYQAIINP---------HHKIEFP--
 .  ..       ||  | .|. | .       |  ... .   .||||||||.||| .|.|||.. |.  .  ..|  ||           ....||  
QMMMTCVNEKRLCGTPLYMAPQILQG-------QGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKD

---VHPNENLLKVLKLCLIRNPHERPTIPTLLNHDFL
   ..  ...   .. .|.... .| ... |.|| ..
GNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase TtkA.AA CMGC 714-917 19 2.6e-38 122.87 In-house 232-559 (513) Show / Hide 
Range on Protein: 714-917
Range on HMM: 232-559/513
Sequence Identity: 19% (66 aa)

YLRIEFIGKGGSGKVYKVLS---------------GDLKIYALKYVCLSDPNEIEAQ------------LNEIEMLKRLR---------------KQVN-
|  |. ||.|  |.|||                   . .|.|.| . .   .|..|.            | ||..||.|.               |. | 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IIQLIDYEVNMA---------------KNYILLVLEFGEIDLSKLLQRLQTPNGT--NVNF---------------IRIYW------QQMLQAVH--TIH
|..|.|. .                   |.. || |. . || ..... |...    ....               |. .       .|.|....   .|
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

EEK--IIHGDLKPAN-FVSVQ--------------------GSLKLIDFGIAKAIQSDDTT------------------NIVRESQIGTINYISPEALID
  .  ||| ||||.|  .. .                    | ||..||| |... . .                    |    ... |  | .|| |. 
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

T----SQGGPKQCMKLGRASDIWSLGCILYEM
     ..      |. . . |.||.|||..||
WKHYTNH---NYSMHYTTPIDMWSVGCIFAEM
Kinase TtkA.AA CAMK 719-981 16 1.8e-37 117.82 In-house 1-425 (425) Show / Hide 
Range on Protein: 719-981
Range on HMM: 1-425/425
Sequence Identity: 16% (72 aa)

FIGKGGSGKVYKVLSG-DL------------KIYALKYVCLS----------------------------DPNEIEAQLNEIEMLKRLRK------QVNI
 .|.|. |||...    .             . .| | .  .                            .|.  .  ..|||..|.|..        ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IQLIDYEVNMA-----------------KNYILLVL---EFGEI-DL-SKLLQRLQTPNG---------------TNVNFIRIYWQQMLQAVHTIHEEKI
|.|...  ..                  .... .|.   |. .  .|   |.....   .                .    | | .|...||| .|. .|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHGDLKPANFVSVQ------------------GSLKLIDFGIAKAIQSDD--------------------TTNIVRESQIGTINYIS-PEALID--TSQG
.| |||| |   ..                  . .|.|||| |. .....                    |..   . . ||  |.. || |    ... 
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

GPKQ-----CMKLGRASDIWSLGCILYEMAFGYPPFKSFS------------NIISKYQAIINPHHK-IEFP---------------VHPN------ENL
.  .         |...|.||.|.||| |  ||||| . .            |.   .. |..     ....               .  .      .  
Q--NATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC

LKVLKLCLIRNPHERPTIPTLLNHDFL
   .. .| ..| .|.||   ||| ..
KDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase TtkA.AA Ciliate-E2-Unclassified 714-981 24 2.6e-36 123.47 In-house 1-352 (352) Show / Hide 
Range on Protein: 714-981
Range on HMM: 1-352/352
Sequence Identity: 24% (90 aa)

YLRIEFIGKGGSGKVYKV--LSGDLKIYALKYVC-------LSDPNEIEAQLNEIEMLKRLR------------------KQVNIIQLIDYEVNMAKNYI
|  |. ||.|| |||||.   . . ..||.|| .       ..  |..   .||.. ....                   .  .|. ..... .  |..|
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQD--KQNI

LLVLEFGE-IDLSKLLQ--------------RLQTPNGTNVNFIR-----IYWQQMLQAVHTIHEEK-IIHGDLKPAN-FVSVQG---SLKLIDFGIAKA
 .|.|. |  ||.. ..              .... .    . ..      |  | ||.   .|... ||| |.|| | ... .|    .|.|||||.| 
YIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKK

IQSD---DTTN----------IVRESQIGTINYI----SPEALIDTSQGGPKQCMKLGRASDIWSLGCILYEMAFGYPPFKSFSNII-------------
.|..   | ||              ...||.||.    .|| |    ....|       ..||||||.||||| |||.||.. . ..             
YQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA-----YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAY

--SKYQAIINPHHKIEFPVHPN-----------ENLLK-VLKLCLIRNPHERPTIPTLLNHDFL
    || |..   .|.|| .|.           .....  |. .|  || .|.|.. .||| ..
RKQLYQNIKQ--KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase TtkA.AA NEK 714-885 29 6e-19 63.69 In-house 1-194 (286) Show / Hide 
Range on Protein: 714-885
Range on HMM: 1-194/286
Sequence Identity: 29% (58 aa)

YLRIEFIGKGGSGKVYKVLS---GDL---KIYALKYVCLS--DPNEIEAQL-NEIEMLKRLRKQVNIIQLIDYEVNMAKNYILLVLEFGEI--DLSKL--
| .|. ||.|  |||||| .   |.    | |..| . ..  .. | .. . ||.  ||.| |  ||.  .|  .   .|..  | |. |   ||...  
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQL-KHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIK

-LQRLQTPNGTNVN-FIRIYWQQMLQAVHTIHEE-----KIIHGDLKPAN-FVSVQGS----LKLIDFGIAKAIQSDDTTNIVRES-QIGTINYISPE
 ... .  .       |  . .||. |.. .|..     ||.| |.||.| | . ...    .|. ||||.|  ..   |.    . |.||  |.|||
SIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNH---TTDMAYTTQVGTPYYMSPE
Kinase TtkA.AA TyrKc 714-981 18 3.2e-10 -57.36 SMART 1-280 (280) Show / Hide 
Range on Protein: 714-981
Range on HMM: 1-280/280
Sequence Identity: 18% (58 aa)

YLRIEFIGKGGSGKVYK-VLSGDLKIYALKYVCLSDPNEIEAQLNEIEMLKRL-RKQVNIIQLIDYEVN-----MAKNYILLVLEFGEIDLSKLLQRLQT
   .. .| |  |.||| ...      | | .  .    .|. ..|......|  .  ||..|. . .      |    ...|.|.   ..  |...|. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEY--MPHGDLKDYLRK

PNGTNVNFIRIYWQQMLQAVHTI-------HEEKIIHGDLKPAN-FVSVQGSLKLIDFGIAKAIQSD------DTTNIVRE--SQI--GTINYISPEALI
. ..      . ....|.  . |       |. ..|| ||   |  |. ..  |  ||| ...| .|      . .  ..|  .      |   .||.. 
HRPK------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-

DTSQGGPKQCMKLGRASDIWSLGCILYEMA-FGYPPF-------KSFSNIISKYQAIINPHHKIE-----FPVHPNENLLKVLKLCLIRNPHERPTIPTL
        .  |   .||.|| |  ..|.  .| .|        .| . .| . ..   .    .     | |.  . . .. | |  ..|..|||  ..
--------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF-VCCPDEMYQIMKQCWHEDPEDRPTFSEI

LNHDFL
  |...
--HECF
Kinase TtkA.AA NEK 905-918 85 4e-07 21.56 In-house 205-218 (286) Show / Hide 
Range on Protein: 905-918
Range on HMM: 205-218/286
Sequence Identity: 85% (12 aa)

SDIWSLGCILYEMA
||||||||.||||.
SDIWSLGCVLYEMC
Kinase TtkA.AA NEK 956-981 23 7.7e-05 13.43 In-house 261-286 (286) Show / Hide 
Range on Protein: 956-981
Range on HMM: 261-286/286
Sequence Identity: 23% (6 aa)

KVLKLCLIRNPHERPTIPTLLNHDFL
... ..| ..|..||..  .|.. |.
NLISQMLQKDPEQRPSCNQILEMPFI
Kinase TtkA.AA CMGC 919-981 17 0.000464 8.21 In-house 432-513 (513) Show / Hide 
Range on Protein: 919-981
Range on HMM: 432-513/513
Sequence Identity: 17% (15 aa)

FGYPPFKSFSNIISKYQ-----------------AIINPHHKIEFPV------HPNENLLKVLKLCLIRNPHERPTIPTLLNHDFL
|. .|.|...|.. ...                   ...| |  |        . .. ..  || .|. .|..|.|.   |.|...
FPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSH-K--F-NHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF