Gene DDB0216374 (Slime mold)

DDB0216374

Species: Slime mold
Alias: DdisK173, DDB0216374
External Links: DictyBase Link ,
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: Ste20-DD1

Sequence

Name Sequence Type Origin Length Description Download
DDB0216374.AA Protein None 485 None Fasta, JSON
DDB0216374.kin_dom Protein Kinase Domain None 258 None Fasta, JSON

Protein domain

Protein domains of DDB0216374.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0216374.AA Ste20-DD1 21-278 76 6.8e-238 796.59 In-house 1-268 (268) Show / Hide 
Range on Protein: 21-278
Range on HMM: 1-268/268
Sequence Identity: 76% (206 aa)

FRVLEVIGQGSFGVVCTC-------INTVNNEVVAIKFLEMEG---EENSSLKKEITILKNTVRCPYIVKYHGCYIKENNLMIVMEYCDGGSILDIMQMC
|...||||||||||||||       .||.||.|.|.||.||..   ||||.|||||.|||||..|||||||||||||||.||||||||||||||||||||
FQIVEVIGQGSFGVVCTCRWMKKKDRNTNNNRVIACKFVEMNADDVEENSNLKKEIDILKNTMDCPYIVKYHGCYIKENMLMIVMEYCDGGSILDIMQMC

SITLTEAQIAAILYQIVEGLVYLHSNKILHRDIKAGNVLVNKLGQAKLADFGVSAILVNTGFKQKTVVGSPYWMSPEVISPPKGSNGYDSKADIWSLGIT
|..|.|.|||||.||||.||||||||.|.|||||||||||||.||.||||||||.|.||.|||..||.|||||||||.|.|||||.|||.||||||||||
SKRLIEEQIAAICYQIVKGLVYLHSNRITHRDIKAGNVLVNKEGQPKLADFGVSTIAVNQGFKMNTVIGSPYWMSPEIIMPPKGSQGYDQKADIWSLGIT

AIEMAESKPPLFNLNPVKVIFVIPFRQAPTLEVPGNWSPEFNDFISVCLNKEADKRPSAVDLLNHPFI
||||||||||.||.|||.||||||..|.|||..|.||||||||||..|||...||||||..|||||||
AIEMAESKPPRFNVNPVRVIFVIPHQQPPTLKIPSNWSPEFNDFIKQCLNMNPDKRPSAQQLLNHPFI
Kinase DDB0216374.AA STE20 21-278 47 7.89999999999e-152 510.69 In-house 1-288 (288) Show / Hide 
Range on Protein: 21-278
Range on HMM: 1-288/288
Sequence Identity: 47% (137 aa)

FRVLEVIGQGSFGVVCTCINTVNNEV----VAIKFLEMEG-----EENSSLKKEITILKNTVRCPYIVKYHGCYIKE----NNLMIVMEYCDGGSILDIM
.  ||.|||||.|.|...... ..|.    |||| ...|      .|  ...||| |.|.   .|.||||.|.|.|.    ..| ||||||.|||..|||
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCK-HPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIM

Q---MCSI-----TLTEAQIAAILYQIVEGLVYLHSNKILHRDIKAGNVLVNKLGQAKLADFGVSAILVN-----TGFKQKTVVGSPYWMSPEVISPPKG
.   .| .     ...|.|||.|......|| |||||.| ||||||.|.|... |..|||||||.| | .      .|| .|.||.||||.||||.  .|
KHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEG

-SNGYDSKADIWSLGITAIEMAESKPPLFNLNPVKVIFVIP--FRQAPTLEV--PGNWSPEFNDFISVCLNKEADKRPSAVDLLNHPFI
  .|||.|.|||||||||||||| .||.|...|....| ||   .. |||.   | .|||||.||...||.|. .|||.| .||.||||
PDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase DDB0216374.AA MST 21-278 50 1.3e-140 449.67 In-house 1-254 (254) Show / Hide 
Range on Protein: 21-278
Range on HMM: 1-254/254
Sequence Identity: 50% (132 aa)

FRVLEVIGQGSFGVVCTCINTVNNEVVAIKFLEMEGEEN-SSLKKEITILKNTVRCPYIVKYHGCYI--KENNLMIVMEYCDGGSILDIMQMCSITLTEA
| ..| .||||.|.|   |.  ....|||| .    .|  ....|||.|...    .||||| | |.  |.| . ||||||..||..|||    .||.|.
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPV--NEDLQEIIKEISIMQQ-CKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLNEQ

QIAAILYQIVEGLVYLHSNKILHRDIKAGNVLVNKLGQAKLADFGVSAILVNTGFKQKTVVGSPYWMSPEVISPPKGSNGYDSKADIWSLGITAIEMAES
|||.|||.   || |||.||. |||||||| |.|. | .||||||||. | .|  |  ||.|.||||.||||    . ..||.||||||||||||||||.
QIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVI----QEIKYDCKADIWSLGITAIEMAEG

KPPLFNLNPVKVIFVIPFRQAPTLEVPGNWSPEFNDFISVCLNKEADKRPSAVDLLNHPFI
.||.... |. ..| || .  ||.  |  ||.|||||.. || |. ..|..| .||.||||
MPPYSDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase DDB0216374.AA STE 21-278 35 2.8e-131 442.42 In-house 1-359 (359) Show / Hide 
Range on Protein: 21-278
Range on HMM: 1-359/359
Sequence Identity: 35% (130 aa)

FRVLEVIGQGSFGVVCTCINT------VNNEV---------VAIKFLEMEG------------------EENSSLKKEITILKNTVR-CPYIVKYHGCYI
.. .|.||.|.||.|....|        ..||         .||| ...|                   ||  ...||| |.|.    .|.||||.|||.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KE-------NNLMIVMEYCDGGSILDIMQ---MCSITLT----------EAQIAAILYQIVEG-LVYLHSNKILHRDIKAGNVLVNKLGQAKLADFGVSA
||       ..| |.|||.||||. ||..   .|  .|.          | |||.|..||..| | ||||..| |||||..|.|.     .||.||||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

ILVNTGF----------------KQKTVVGSPYWMSPEVISPPKGS--NGYDSKADIWSLGITAIEMAESKPPLFNLNPVKVIFVIPFR-----------
.|....                 | .|.||.| ||.||||.. ...  .||| |.||||||.|.||||. |||.....| ...| |||            
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----QAPTLEV-----------------PGNWSPEFNDFISVCLNKEADKRPSAVDLLN--HPFI
    . |.|.                  | .|||||.|||. ||.|. .|||.| .||.  ||||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase DDB0216374.AA YSK 21-278 46 1e-111 337.69 In-house 1-257 (257) Show / Hide 
Range on Protein: 21-278
Range on HMM: 1-257/257
Sequence Identity: 46% (123 aa)

FRVLEVIGQGSFGVVCTCINTVNNEVVAIKFLEMEGEENS--SLKKEITILKNTVRCPYIVKYHGCYIKENNLMIVMEYCDGGSILDIMQM-CSITLTEA
|  .|.|| ||||.|   |. . ..||||| .. |  |     . .||..|       || || | | |   | |.|||| |||.|| |       . | 
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSP-YITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQFDEK

QIAAILYQIVEGLVYLHSNKILHRDIKAGNVLVNKLGQAKLADFGVSAILVNTGFKQKTVVGSPYWMSPEVISPPKGSNGYDSKADIWSLGITAIEMAES
.|| ||  |  || ||||.. .|||||| |||... |. ||.||||.. . .|  |  | ||.|||| ||||   ..  .||.|||||||||||.|||  
YIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVIC--QEVSYYDFKADIWSLGITAYEMAKG

KPPLFNLNPVKVIFVIPFRQAPTLEVPG-NWSPEFNDFISVCLNKEADKRPSAVDLLNHPFI
 ||.  . | .| | || .. |.||  | ..|  | .|. .||||.  .|||| .|| | ||
EPPYCDYHPMRVMFLIPKNNPPKLE--GRSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase DDB0216374.AA PAKL 21-278 46 3.5e-100 339.12 In-house 1-256 (256) Show / Hide 
Range on Protein: 21-278
Range on HMM: 1-256/256
Sequence Identity: 46% (121 aa)

FRVLEVIGQGSFGVVCTCINTVNNEVVAIKFLEMEGE-ENSSLKKEITILKNTVRCPYIVKYHGCYIKE-NNLMIVMEYCDGGSILDIMQMCSITLTEAQ
|   |  ||||.| |   |    | . ||| .|.    |  .. ||| |||.  .||.|| | |    . |.. | |.||  ||| |.|. |  ||.|.|
FEFQEKLGQGSYGSVYKAIHKDTNFPLAIKVIEIKESNEIKDIEKEIQILKK-CKCPNIVSYFGSIQQKLNHYWILMDYCSLGSINDMMESCCKTLNEKQ

IAAILYQIVEGLVYLHSNKILHRDIKAGNVLVNKLGQAKLADFGVSAILVNTGFK--QKTVVGSPYWMSPEVISPPKGSNGYDSKADIWSLGITAIEMAE
|. || |   ||.||||  | |||||| |.| |  .| |.||||||  | .. .    .  .|.|||| ||.|        |..|.|||||||||||||.
ISVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQL-QDEYDGQANQMIGTPYWMAPEIIN----KQNYNNKCDIWSLGITAIEMAD

SKPPLFNLNPVKVIFVIPFRQAPTLEVPGNWSPEFNDFISVCLNKEADKRPSAVDLLNHPFI
. ||.  ..| .    || .  ||.  |  |||.||||.  |. |   ||.|. ||| ||||
GFPPHYDMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase DDB0216374.AA S_TKc 21-278 31 1e-98 335.18 SMART 1-231 (231) Show / Hide 
Range on Protein: 21-278
Range on HMM: 1-231/231
Sequence Identity: 31% (86 aa)

FRVLEVIGQGSFGVVCTCINTVNNEVVAIKFLEMEGEENSSLKKEITILKNTVRCPYIVKYHGCYIKENNLMIVMEYCDG--GSILDIMQMCSI-----T
...|..||.|.||.|. |...  ...|||| .        ....|| |||.  ..|.|||.....   ..| .|||||||  |. .|... .        
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LTEAQIAAILYQIVEGLVYLHSNKILHRDIKAGNVLVNKLGQAKLADFGVSAILVNTGFKQKTVVGSPYWMSPEVISPPKGSNGYDS-KADIWSLGITAI
..| ... ..|||...| |.||..|.|||.|  |.|...  . |..|||....|       .|..|.|..|.|||.       ||.  |.|.||.|.. .
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL-------GYGKCKCDWWSCGCILY

EMAESKPPLFNLNPVKVIFVIPFRQAPTLEVPGNWSPEFNDFISVCLNKEADKRPSAVDLLN-------HPFI
||.  .||    .. ... .|              |||. |||. ||.|. .|||.| ..|.       ||..
EMLCGYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DDB0216374.AA PAKA 21-278 38 4.8e-89 302.14 In-house 1-260 (260) Show / Hide 
Range on Protein: 21-278
Range on HMM: 1-260/260
Sequence Identity: 38% (103 aa)

FRVLEVIGQGSFGVVCTCINTVNNEV--VAIKFLEMEGEENS-SLKKEITILKNTVRCPYIVKYHGCYIKENNLMIVMEYCDGGSILDIMQMCSI----T
....| ||||. | | ...|. .|.   |||| ..|. .     .. || ..|.  . . ||.|   |. .  | .|||| .||.  |. . |      .
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVMKE-CKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCNY

LTEAQIAAILYQIVEGLVYLHSNKILHRDIKAGNVLVNKLGQAKLADFGVSAILVNTGFKQKTVVGSPYWMSPEVISPPKGSNGYDSKADIWSLGITAIE
..|.|||... ..  || ..||... |||||  |.|... |. |..|||  | |    .| .|.|| ||||.||||.     . || | ||||||| |||
MDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIR----RKQYDEKVDIWSLGIMAIE

MAESKPPLFNLNPVKVIFVIPFRQAPTLEVPGNWSPEFNDFISVCLNKEADKRPSAVDLLNHPFI
|.|. ||  | .|.. .. |    .| .  | .||.||.|| . ||... |.|.|| .||.|||.
MIEGEPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase DDB0216374.AA Pkinase 21-278 28 1.1e-87 302.4 Pfam 1-293 (293) Show / Hide 
Range on Protein: 21-278
Range on HMM: 1-293/293
Sequence Identity: 28% (86 aa)

FRVLEVIGQGSFGVVCTCINTVNNEVVAIKFLEMEGEENSSLKK-----EITILKNTVRCPYIVKYHGCYIKENNLMIVMEYCDGG----SILDIMQ-MC
......||.||||.|. |..  ....||.| .. ..|. . ..      || |.|.  ..|.||......  .... .|||||.||    .  |... . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

SITL--TEAQIAAILYQIVEGLVYLHSNKILHRDIKAGNVLVNKLGQA----KLADFGVSAIL-VNTGFKQKTVVGSPYWMSPEVISPPKGSNGYDSKAD
. ..  .| ..  ..|||..|| |.||..|.|||.|  |.|... |.     |..|||... .    .   .|..|.|..|.||||    |...|..|.|
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR---GGQYYGPKVD

IWSLGITAIEMAESKPPLFNL----NPVKVIFVIPFRQAPTLEVPGNWS---------------------PEFNDFISVCLNKEADKRPSAVDLLNHPFI
.||.|.. .||.  .||  .     | .  ...|  .  | |. .  |.                     .|. |||. ||.|   |||.| ..|.||..
MWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase DDB0216374.AA NinaC 21-278 40 4.7e-83 282.24 In-house 1-267 (267) Show / Hide 
Range on Protein: 21-278
Range on HMM: 1-267/267
Sequence Identity: 40% (109 aa)

FRVLEVIGQGSFGVVCTCINTVNNEVVAIKFLEMEGEENSSLKKEITILKNTVRCPYIVKYHGCYIKEN-----NLMIVMEYCDGGSILDIMQ---MCSI
. . | ||.| .| |    |  | ...|.| ..   . . .   |  ||.     | .|.. | | |        | .||||| |||. |. .    |  
WEIYETIGKGTYGKVFKVKNKDNGQIAAVKIQHYIHDHDEEIEAEYNILRDYCDHPNVVRFYGMYYKKDKCNGDQLWFVMEYCNGGSVTDMVKGLLKCGR

TLTEAQIAAILYQIVEGLVYLHSNKILHRDIKAGNVLVNKLGQAKLADFGVSAILVNTGFKQKTVVGSPYWMSPEVISPPKGSNG-YDSKADIWSLGITA
 . |. || ||.  . ||  ||.|...|||.|  |.|  . |  || |||||| |  |  .  | ||.|.|| ||||.  .  .  ||  .|.|||||||
RMREEHIAYILHEACMGLQHLHCNHVIHRDVKGNNILLTTEGGVKLCDFGVSAQLDSTRHRRNTCVGTPCWMAPEVIACMQQYDPDYDARCDVWSLGITA

IEMAESKPPLFNLNPVKVIFVIPFRQAPTLEVPGNWSPEFNDFISVCLNKEADKRPSAVDLLNHPFI
||..  .||.... |.. .| ||    |||  | ||. ||||||| || |.. |||. |..|.||||
IELGDGDPPFADMHPMRAMFKIPRNPPPTLMHPENWCQEFNDFISQCLEKDYEKRPMMVHMLEHPFI
Kinase DDB0216374.AA KHS 21-278 40 6.1e-83 278.79 In-house 1-258 (258) Show / Hide 
Range on Protein: 21-278
Range on HMM: 1-258/258
Sequence Identity: 40% (107 aa)

FRVLEVIGQGSFGVVCTCINTVNNEVVAIKFLEMEGEEN-SSLKKEITILKNTVRCPYIVKYHGCYIKENNLMIVMEYCDGGSILDIMQMCSITLTEAQI
. .|  .| | .| |    ... .|..|.| . || ... .....||...| . | | || |.| |.... | |.|||| |||. || ..    |.| ||
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDFAVIQQEIMMMK-DCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVTG-PLSELQI

AAILYQIVEGLVYLHSNKILHRDIKAGNVLVNKLGQAKLADFGVSAILVNTGFKQKTVVGSPYWMSPEVISPPKGSNGYDSKADIWSLGITAIEMAESKP
| .  ....|| ||||.. .|||||  |.|... |. ||||||||| .  |  | |  .| |||| ||| .  .   ||.   |||..||||||.|| .|
AYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVER-KGGYNQLCDIWAVGITAIELAELQP

PLFNLNPVKVIFVIPFR--QAPTLEVPGNWSPEFNDFISVCLNKEADKRPSAVDLLNHPFI
|.|.| |....|..     | |.|.    ||. | .|. ..| |.. |||.|  ||.|||.
PMFDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase DDB0216374.AA SLK 21-278 41 5.6e-81 272.93 In-house 1-259 (259) Show / Hide 
Range on Protein: 21-278
Range on HMM: 1-259/259
Sequence Identity: 41% (107 aa)

FRVLEVIGQGSFGVVCTCINTVNNEVVAIKFLEMEGEEN-SSLKKEITILKNTVRCPYIVKYHGCYIKENNLMIVMEYCDGGSILDIMQMCSITLTEAQI
. ..  .| | || |    .  .. . | | .|.. ||. .    || || .    |.|||  . |  .|.|....|.|||| .  ||     .||| ||
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKDEEELEDYMVEIDILSECK-HPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIMVELEHPLTEDQI

AAILYQIVEGLVYLHSNKILHRDIKAGNVLVNKLGQAKLADFGVSAILVNTGFKQKTVVGSPYWMSPEV-ISPPKGSNGYDSKADIWSLGITAIEMAESK
. . ....|.| .|||||..|||.||||.|.   |. .|||||||| . .|  |. | .| |||| ||| .      . || |||||||||| ||||.  
QYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMAQME

PPLFNLNPVKVIFVIPFRQAPTLEVPGNWSPEFNDFISVCLNKEADKRPSAVDLLNHPFI
||  ..||..|.. |   . |||| |  || ||.||.  ||.|....|... .|..|...
PPHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase DDB0216374.AA Pkinase_Tyr 21-164 27 2.3e-32 110.22 Pfam 1-158 (270) Show / Hide 
Range on Protein: 21-164
Range on HMM: 1-158/270
Sequence Identity: 27% (44 aa)

FRVLEVIGQGSFGVVCTCINT----VNNEVVAIKFL--EMEGEE--NSSLKKEITILKNTVRCPYIVKYHGCYI-KENN--LMIVMEYCDGGSILDIMQM
 . ....|.|.||.|. .. .     ..  ||.| |      |.    .. .|. |.|.  ..| ||...|. . ..    ..|||||. .|. ||  . 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

C---SITLTEAQIAAILYQIVEGLVYLHSNKILHRDIKAGNVLVNKLGQAKLADFGVS
       ||  ..  . .|| .|. ||.|... |||. | |.||.. ...| .||| .
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase DDB0216374.AA TyrKc 21-278 23 1.7e-25 91.91 SMART 1-280 (280) Show / Hide 
Range on Protein: 21-278
Range on HMM: 1-280/280
Sequence Identity: 23% (69 aa)

FRVLEVIGQGSFGVVCTCINTVNNEVVAIKFLEMEGEENSSLKKEITILKNT-VRCPYIVKYHGCYIKE-------NNLMIVMEYCDGGSILDIMQMCSI
 . ....| | ||.|. .. .   . ||.| |  .      . .|. |...   . | ||. .|. ...         |||||||...|. .|  . .  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

TLTEAQIAAILYQIVEGLVYLHSNKILHRDIKAGNVLVNKLGQAKLADFGVSAILVNT---GFKQKTVV-----GSP-----YWMSPEVISPPKGSNG-Y
.|. ..   . .|| .|  ||||... |||. | |.||.. ...| .||| |  . .    |  ... .     |.       ||.||.|       | .
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-----NYGKF

DSKADIWSLGITAIEMAES-KPPLFN-----LNPVKVIFVIPFRQAPTLEVPGN--------WSPEFNDFISVCLNKEADKRPSAVDLLNHPFI
 .| |.|| |..  |.    ..|  .     ...  ||  .  .|   .. | |         ..|  . .. | . ....||.  ..  | ..
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYV--KQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase DDB0216374.AA Pkinase_Tyr 183-278 23 3e-05 18.4 Pfam 180-270 (270) Show / Hide 
Range on Protein: 183-278
Range on HMM: 180-270/270
Sequence Identity: 23% (23 aa)

WMSPEVISPPKGSNGYDSKADIWSLGITAIEMAE-SKPP-LFNLNPVKVIFVIPFRQAPTLEVPGNWSPEFNDFISVCLNKEADKRPSAVDLLNHPFI
||.||.|.  |    . .| |.|| |..  |.    . |   .. .  |.  |  .    .. | | ..|  | .  | ......||.  ..  | ..
WMAPECINYGK----FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYR-MPCPENCPDEIYDLMKQCWHYDPEDRPTFSEI--HEQL