Gene DDB0230002 (Slime mold)

DDB0230002

Species: Slime mold
Alias: DdisK146, DDB0230002
External Links: DictyBase Link ,
Annotation:

Classification

Group: STE
Family: Dicty3
Subfamily: Dicty3-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
DDB0230002.AA Protein None 536 None Fasta, JSON
DDB0230002.kin_dom Protein Kinase Domain None 134 None Fasta, JSON

Protein domain

Protein domains of DDB0230002.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0230002.AA Dicty3-Unclassified 15-159 39 2.6e-75 255.94 In-house 2-216 (252) Show / Hide 
Range on Protein: 15-159
Range on HMM: 2-216/252
Sequence Identity: 39% (85 aa)

IIEKNYRKGGFSKISKAKKKNG---IINGTIVNKKMIAIKKIKFDDKIQFN--------EVNN--------LELIK----------NKNKEMQISSIIDY
.||.   ||.||.|.||.|||.   |.|..|....|...|||..|||||||        |.||        .|.||          ||.|.|||..||||
VIERQLSKGSFSQIYKAHKKNDPNFICNIKIIQYCMFTMKKIDYDDKIQFNKFVKYYSLEFNNSKTYAYIIMEFIKGESMKSIIENNKFKDMQIKEIIDY

FGYGIKGKN-KLYIYLEFIEGKTIYELKKKKFPLNEKQ--------------------------ISIILKKCLETMKFLHNN-------------CNLIH
|||.||.|| |.|....|......|......|..|.||                          ||||.|||..||||||||             ||.||
FGYAIKYKNDKGYMHRDFKPENIMYQNQNQNFNQNNKQNLKLIDFGLSKAINENIINKTVKLQTISIIGKKCYMTMKFLHNNKGSNSSLDIWSLGCNIIH

MDLKCDNIIL-KPNN
||.||..|.| .|||
MDWKCNQICLQRPNN
Kinase DDB0230002.AA Dicty3 22-155 35 4e-55 180.39 In-house 1-145 (351) Show / Hide 
Range on Protein: 22-155
Range on HMM: 1-145/351
Sequence Identity: 35% (52 aa)

KGGFSKISKAKKKNGIINGTIVNKKMIAIKKIKFDDKIQFNEVNNLELIKNKNKEMQISSIIDYFG--YGIKGKN-KLYIYLEFIEGKTIYEL-------
............|....|..|.|.||..|..||...|..||||||.. .|..||.|....|..|.|  |.....| ..|||.|.|||.....        
WSIGGCGNFGRVKKCHKNNCIINIKMVDICHIKIINKCDFNEVNNWRHEKIINKKMRHPCIVKYYGACYCCDNNNDNHYIYMEYIEGEIPISFVKTNNML

-KKKKFPLNEKQISIILKKCLETMKFLHNNCNLIHMDLKCDNIIL
 |.|....||..||.|......|....|.||..||.|.|||||.|
KKHKNNRFNEHEISKIICDLVKTLNYIHKNCHIIHRDIKCDNIML
Kinase DDB0230002.AA STE 22-213 19 2.5e-23 79.31 In-house 9-197 (359) Show / Hide 
Range on Protein: 22-213
Range on HMM: 9-197/359
Sequence Identity: 19% (45 aa)

KGGFSKISKAKKKNGI---INGTIVN----KKMIAIKKIKFDD---------------KIQFNEVNNLELIKNKNKEMQ-ISSIIDYFGYGIKG------
||.| .  ||.... .    .| . |    ....|||......               | . .. . |. ||  .|  .    |. |.|. .|.      
KGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKN

KNKLYIYLEFIEGKTIYELKKKKF----PLN----------EKQISIILKKCLET-MKFLHNNCNLIHMDLKCDNIILKPNNYDNNNNNNNNNNNNNNNN
...|.|..|...| .. .. |.|.    |||          |.||..|.. .|.  ...||..   || |.|..|| |                      
DDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH-IIHRDIKPANILL----------------------

NNNSNINDDNNNSNSNINDDNNFDIKIIDYGLSQKI
                        .|..| |.. ..
------------------------VKLCDFGVCGQL
Kinase DDB0230002.AA FNIPK 13-210 30 5.5e-19 59.77 In-house 1-271 (425) Show / Hide 
Range on Protein: 13-210
Range on HMM: 1-271/425
Sequence Identity: 30% (84 aa)

WEIIEKNYRKGGFSKISKAKKKNGIINGTIVNKKMIAIKKIKFDDKIQFNEVNNLELIKNKNKEM------QISSIIDYFGYGIKGK-N-KLYIYLEFIE
||||.    .| |..  |||| |...|| .||  . .||.||  || . .  |. | ..  ...       .  .|  | ||. ... .  .|||.|.|.
WEIIST-LKSGNFGRVCKAKKINCQFNGNRVN--FCIIKIIKKKDKYYYFKWNEIEIHIKLRDCKEILEKIKHICIMKYYGYC-CDEIDHNFYIYMEYID

G-KTIYE------LKKKK---FPLNEKQISIILKKCLETMKFLHNNC-NLIHMDLKCDNIILKPNN------------------YDNNNN----------
|   | .      |||.    ||  |. ||..  .  .  . .|.|    || |.|||||..   .                   |||||          
GYIPISYVKTNNLLKKHPHNQFP--EDIISRCMCDLVKSLNCIHENGRHIIHRDIKCDNIMIVNDEFHSCDFDYNCSKDISYYSKDNNNNFFTEDCVCNV

------------------------------NNNNNNNNNNNNNNNSNINDDNNNSNSNINDDNNFD--IKIIDYGLS
                               ||||||||||||||.|.|  ||| .  .|  .|    .|.||.|||
NGSGTDENCKSCKLKSKPIREIQGSCESCGSNNNNNNNNNNNNNNNNNNNNNNNNCNANNCNYNTNNKWKFIDFGLS
Kinase DDB0230002.AA S_TKc 14-305 17 3.8e-14 30.58 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-305
Range on HMM: 1-231/231
Sequence Identity: 17% (57 aa)

EIIEKNYRKGGFSKISKAKKKNGIINGTIVNKKMIAIKKIKFDDKIQFNEVNNLELIKNKNKEMQISSIIDYFGYGIKGKNKLYIYLEFIEG--KTIYE-
  | .   ||.|.|  |...|.         ..  |||.||   .   .|.. |.         .   |. ....     ..||. .|...|   . .. 
YEILRKIGKGAFGKVYKCRHKK--------TGRIVAIKIIK---EHIRREIQILKK--------HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDY

LKKKKFP-----LNEKQISIILKKCLETMKFLHNNCNLIHMDLKCDNIILKPNNYDNNNNNNNNNNNNNNNNNNNSNINDDNNNSNSNINDDNNFDIKII
.||.. .     ..| ..  ...  .. ....|.. . || ||| .|| |                                              |||.
IKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE-------------------------------------------HIKIC

DYGLSQKIGDLKRDHYGT------YLPDECILNNVSIVNYTF---DVYSLGFISFELFY---PTQFEIKPIKLTHIYEYVEKSQISPLFLNFIKKCIG--
| ||. ..         |      |.. | .        |..   |..|.| | .|...   | .       .  ... .     || ...||.||    
DFGLARQL--------TTFCGTPWYMAPEVL-------GYGKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG----SPEAKDFIRKCLQKD

---RYLDIDVLE------IHPFL
   |.   ..|.      .||..
PEKRPTA-EALQDEWDIKCHPWF
Kinase DDB0230002.AA Ciliate-E2 14-255 17 7.2e-14 43.97 In-house 1-291 (365) Show / Hide 
Range on Protein: 14-255
Range on HMM: 1-291/365
Sequence Identity: 17% (59 aa)

EIIEKNYRKGGFSKISKAKK-KNGI------INGTI---------VNKKMIAIKKIKFDDKIQFNEVNNLE---------LIKNKN--KEMQISSIIDYF
 .. |   .|.|... |.|. |..       |. ..         |..|..|.| .| ....|.. ....          . ..||  ....   || ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKI-NEKNILEQLNHPNIIKMY

GYGI-KGKNKLYIYLEFIEGKTIYE---LKKKKF--------PLNEKQISIILKKCLE---------------TMKFLHNNCNLIHMDLKCDNIILKPNN
 . . | .|..|. .|...|.. ..    .|||.        ...||.|. | |. |.                ...||.. | || |.| .||..    
ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

YDNNNNNNNNNNNNNNNNNNNSNINDDNNNSNSNINDDNNFDIKIIDYGLSQKIGDLKRDHYG------------------------------------T
                                          ||||| |||.|. |   ....                                     
------------------------------------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPG

YLPDECILN-------NVSIVNYTFDVYSLGFISFELFY
|.. | . .       .    .|  |..||| | .|. .
YMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF
Kinase DDB0230002.AA Ciliate-E2-Unclassified 14-255 19 4.1e-12 38.33 In-house 1-265 (352) Show / Hide 
Range on Protein: 14-255
Range on HMM: 1-265/352
Sequence Identity: 19% (60 aa)

EIIEKNYRKGGFSKISKAKKKNGIINGTIVNKKMIAIKKIKFDDKI----QFNEVNNLELIKNKN--------KEMQI------SSIIDYFGYGIKGKNK
 .| |   .|||.|. |...|.   ..  .. . ...|......|.    . ...|... ..||.        |.||       . .| .. |  . |..
YKIIKQIGQGGFGKVYKCQHKK---QK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQN

LYIYLEFIEGKTIYE-LKKKKF----------------PLNEKQIS-----IILKKCLETMKFLHNNCNLIHMDLKCDNIILKPNNYDNNNNNNNNNNNN
.|| .|..||..  . .||.|.                 . |.|..      ...  |.  ..|| . | || |.|..||... |..             
IYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK-------------

NNNNNNNSNINDDNNNSNSNINDDNNFDIKIIDYGLSQKIGDL--------------KRDHY----GTYL------PDECILNNVSIVN--YTFDVYSLG
                         |. |||||.|.| |...               |....    ||.       . |.. ..       |  |..|||
-------------------------NYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLG

FISFELFY
 | .|. .
VILYEMLF
Kinase DDB0230002.AA CMGC 22-210 16 1.2e-11 33.64 In-house 9-251 (513) Show / Hide 
Range on Protein: 22-210
Range on HMM: 9-251/513
Sequence Identity: 16% (46 aa)

KGGFSKISKAKKKN-------GIINGTIVNKKMIAIKKIK--FDDKIQ--------------FNEVNNLELIKNK-------------NKEMQISSIIDY
.| ...  |.. |.       |.   .. .....||||||  | ...|              . |.  |. ....             ...  | ...|.
EGTYGVVYKCRDKRTNQKKDNGQ-AHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNIVKLYDI

FGYG--------------IKGKNKLYIYLEFIEGKTIYELKKKKF--------PLNEKQ------------ISIIL------KKCLETMK--FLHNNC-N
| .               .   |.||.  |...      .|...|        ||.| .            |  ..      .  |. .|  ..| .. |
FYHKNSDGNEYEDKHIISQ-HFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGN

LIHMDLKCDNIILKPN-----------NYDNNNNNNNNNNNNNNNNNNNSNINDDNNNSNSNINDDNNFDIKIIDYGLS
 || |||  || . .|           .                           . . |..   . |. .||.| ||.
IIHRDLKPENILINHNCELITRMMWKSE---------------------------D-W-NPC---QKNGRLKICDFGLA
Kinase DDB0230002.AA Ciliate-E2a 91-218 24 6.7e-09 22.35 In-house 69-165 (275) Show / Hide 
Range on Protein: 91-218
Range on HMM: 69-165/275
Sequence Identity: 24% (33 aa)

KGKNKLYIYLEFIEGKTIY-ELKKKK-FPLNEKQISIILKKCL-ETMKFLHNNCNLIHMDLKCDNIILKPNNYDNNNNNNNNNNNNNNNNNNNSNINDDN
...| .|. .|..||.. | ..|..| |  ....|. |... | .    .|.. | .| ||| .||..|                               
EDENNYYLVMEYCEGGELYDKIKQCKRFFEEIQEICDIMQQLLWQGLHYMHQR-NIMHRDLKPENILFKN------------------------------

NNSNSNINDDNN---FDIKIIDYGLSQKI-GDLKR
       .. |.   .|||||| ||...| .| |.
-------CSKNSIQNSDIKIIDFGLATFIDKDEKK
Kinase DDB0230002.AA CAMK 22-223 13 1.6e-08 22.8 In-house 4-282 (425) Show / Hide 
Range on Protein: 22-223
Range on HMM: 4-282/425
Sequence Identity: 13% (42 aa)

KGGFSKISKAKKK-NG-IIN-------GTIVNKKMIAIKKIKF-------------------------DDKIQ--FNEVNNLELIKNKNK---EMQISSI
.|.|.|  ... | ..  ..       |. |  |.|  ||.|                          . . .  ..|.. . .......      | ..
RGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKL

IDYFGY-------GIKG---------KNKLYIYL---EFIEGK----TIYELKKKK---------------FPLNEKQISIILKKCLETMKFLHNNCNLI
....          . .         ....|. .   |...|      ...  ...               . ..|.. . . .  .. ....|..   .
YEVYEDPHYFKNTND-YETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN-IV

HMDLKCDNIILKPNNYDNNNNNNNNNNNNNNNNNNNSNINDDNNNSNSNINDDNNFDIKIIDYGLSQKI--------------------------GDLKR
| |||..|| |  || |...     .            |  |           ||..||||| |...|.                          |.. .
HRDLKPENILLDDNNDDSDP-V-E-HD----------EIF-D----------WNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMK

DHYGT
.  ||
TFCGT
Kinase DDB0230002.AA Pkinase 22-210 18 3.7e-08 29.91 Pfam 9-159 (293) Show / Hide 
Range on Protein: 22-210
Range on HMM: 9-159/293
Sequence Identity: 18% (36 aa)

KGGFSKISKAKKKNGIINGTIVNKKMIAIKKIKFDDKIQ-FN--EVNNLELIKNKNKEMQISSIIDYFGYGIKGKNKLYIYLEFIEGK----TIYELKK-
.|.|..  |...|.  .   ||  | |  ...| . ... ..  |.  .  .. .|    |  ..|.| .    |...|. .|. ||       ... . 
SGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPN----IVRLYDWFED----KDHIYMVMEYCEGGLYVMDLFDYIST

-KKFPL--NEKQISIILKKCLETMKFLHNNCNLIHMDLKCDNIILKPNNYDNNNNNNNNNNNNNNNNNNNSNINDDNNNSNSNINDDNNFDIKIIDYGLS
 .. ..   |...  ...  |. ....|. .. || ||| .|| .. ||....                                     ..||.| ||.
WRHGCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILID-NNGHIDA------------------------------------CVKICDFGLA
Kinase DDB0230002.AA PAKA 117-155 38 4.4e-08 24.63 In-house 99-136 (260) Show / Hide 
Range on Protein: 117-155
Range on HMM: 99-136/260
Sequence Identity: 38% (15 aa)

PLNEKQISIILKKCLETMKFLHNNCNLIHMDLKCDNIIL
...|.||. ... ||  ..|.|.. . || |.| ||| |
YMDEGQIAYVCRECLQGLEFIHSK-HRIHRDIKSDNILL
Kinase DDB0230002.AA TyrKc 14-294 16 2.5e-05 -136.5 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-294
Range on HMM: 1-280/280
Sequence Identity: 16% (59 aa)

EIIEKNYRKGGFSKISKAKKKNGIINGTIVNKKMIAIKKIKFDDKIQ--FNEVNNLELI--KNKNKEMQISSIIDYFGYGIKGK------NKLYIYLEFI
   .|    | | .. |.. |            . |.|..| |  ..   .| . .  .  ...|       |.  .|. ....        |.| .|. 
ITLGKKLGEGAFGEVYKGTWK-----------IQVAVKMLKEDA-REDFMREARIMCKLGGHHPN-------IVRLYGVCTQQGRNFMYIEPLMIVMEYM

EG----KTIYELKKKKFPLNEKQISIILKKCLETMKFLHNNCNLIHMDLKCDNIILKPNNYDNNNNNNNNNNNNNNNNNNNSNINDDNNNSNSNINDDNN
..    . . . ..|   |. |.   .     . | .|| . |.|| || . |. .. |.                                        
PHGDLKDYLRKHRPK---LCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENH----------------------------------------

FDIKIIDYGLSQKIG---------DLKRDHY---GT------YLPDECILNNVSIVNYTF--DVYSLGFISFELF------YPTQFEIKPIKLTHIYEYV
  .|| | ||| .|.         | .|      |        .. |||  ..    .|.  ||.| |   .|.|      || . .  ... ....|||
-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK----FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYV

EKSQISPLFLN---------------FIKKC-------------IGRYL
..    |   |                .|.|             | ...
KQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
FNIP DDB0230002.AA FNIP 348-373 33 5.363293 3.5 Pfam 6-32 (46) Show / Hide 
Range on Protein: 348-373
Range on HMM: 6-32/46
Sequence Identity: 33% (9 aa)

ITSEQFPNNSKMIEFGDDFNGIIN-VD
.. . .||. | ..|||.||  |. ..
LEKGCLPNSIKHLIFGDNFNQPIEDIN
FNIP DDB0230002.AA FNIP 443-474 27 0.021854 11.88 Pfam 14-46 (46) Show / Hide 
Range on Protein: 443-474
Range on HMM: 14-46/46
Sequence Identity: 27% (9 aa)

NTKHLIL-KNYKNYIRHRGIIPEGVTFLELSDS
. ||||. .|..  |.  . .|  ...||....
SIKHLIFGDNFNQPIEDINVLPNSLKHLEFGYC
FNIP DDB0230002.AA FNIP 486-498 46 1.131305 5.87 Pfam 34-46 (46) Show / Hide 
Range on Protein: 486-498
Range on HMM: 34-46/46
Sequence Identity: 46% (6 aa)

LPKSIEELCFGCT
||.|...| ||. 
LPNSLKHLEFGYC