Gene DDB0230010 (Slime mold)
DDB0230010
Group:
STE
Family:
STE-Unique
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| DDB0230010.AA | Protein | None | 1224 | None | Fasta, JSON |
| DDB0230010.kin_dom | Protein Kinase Domain | None | 259 | None | Fasta, JSON |
Protein domains of DDB0230010.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | DDB0230010.AA | STE-Unique | 1003-1193 | 34 | 2.2e-109 | 369.73 | In-house | 368-616 (616) | Show / Hide |
Range on Protein: 1003-1193
Range on HMM: 368-616/616
Sequence Identity: 34% (85 aa)
HVWIILEYCDGGTVRDLLQATCTPGNPNNLQLFEETLIAYIITELLEGLVYLRSKG--IIHRDLKSRNILLTRKG-----KVKIADFGLATTCSLG----
.|||..|||..||..........||||||||||.||.........||||.||.|.. |||||||..||.....| ||||.|||.||.|...
WVWIFMEYCEHGTLQQIIKRCGCPGNPNNLQLFPETEVIWYTYQILEGLEYLHSQHNPIIHRDLKPHNIFCMQDGKGRVCKVKICDFGHATCCQPDHFEK
-----------------------------------RGRTRMCGTMGRIAPEVIRRE-----PYDTQSDIYSLGCLIIEMAEGTVPYGKDSSLKALFYTAI
......|||.....||||... ||||..||.||||....|..|..|........|.....|
DNNSKNSNTWININNNSSTNSTAQQTPMWDLNINNYTMKYCCGTPCYMCPEVINCRNQINNPYDTKVDIWSLGCMCFHMCCGCPPWHQRYHMQAYIEMCI
HQYKLPN-------PKKYTKEFVDFLYLCLNPDPFKRPTPEMLLHHTFL
|....|. |.|...|...|...||...|..||....||||..|
HIHCQPPQCPIENIPPKCQPEQQQFIEKCLERNPHHRPSAHQLLHHFWL
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| Kinase | DDB0230010.AA | STE | 935-1193 | 29 | 3.6e-104 | 352.36 | In-house | 1-359 (359) | Show / Hide |
Range on Protein: 935-1193
Range on HMM: 1-359/359
Sequence Identity: 29% (107 aa)
FRDKIKLGTGAFGNVFYAIRK------SDSSP---------VAIKVLMERT------------------KKDSPIIPELYIHSACN--HSNIVTYIESYL
... |.| |||| |..|... . .|||.. .. .. |. |. |.. || | |||.|. .|.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF
CKG-------HVWIILEYCDGGTVRDLLQATCTPGNPNNLQ-----LFEETLIAYIITELLEG-LVYLRSKGIIHRDLKSRNILLTRKGKVKIADFGLAT
.| ..||..||.|||...|... .. .|.|.|.. |.|..||||. ..|.| | || |..|||||.|. |||| ||..|||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG
TCSL-----------------GRGRTRMCGTMGRIAPEVIRR------EPYDTQSDIYSLGCLIIEMAEGTVPYGKDSSLKALFYTAIHQ----------
. . |. ..|| |||||.. .|||..||.||||.|||||.| .|. . . ..|.|.... .
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC
------YKLPN-----------------PKKYTKEFVDFLYLCLNPDPFKRPTPEMLLH--HTFL
.||. |.|...|| ||. .||. || ||||.. ||. | |.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
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| Kinase | DDB0230010.AA | STE20 | 935-1193 | 37 | 3.2e-88 | 299.4 | In-house | 1-288 (288) | Show / Hide |
Range on Protein: 935-1193 Range on HMM: 1-288/288 Sequence Identity: 37% (107 aa) FRDKIKLGTGAFGNVFYAIRKSDSSP----VAIKVLMERT-----KKDSPIIPELYIHSACNHSNIVTYIESYLCK----GHVWIILEYCDGGTVRDLLQ . . |.| |..| |. |. |. ||||.. .. .. |. | | . |.| |||.|..||| . . ||. |||.||...|... YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK ATCTPGNPNNLQ-LFEETLIAYIITELLEGLVYLRSKGIIHRDLKSRNILLTRKGKVKIADFGLATTCS------LGRGRTRMCGTMGRIAPEVIRR--- .... |... . ..| |||| |.|.|| || |..|||||.|. ||||| .|.||.||||.. . .. | ..|| |||||.. HCMKCGKNHK-GHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEG --EPYDTQSDIYSLGCLIIEMAEGTVPYGKDSSLKALFYTAIHQYKLP---N--PKKYTKEFVDFLYLCLNPDPFKRPTPEMLLHHTFL .||. .||.||| .|||||| .|| . . ..|.|... | . | . |.|...|| ||. .||. || ||||.. ||.| |. PDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI |
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| Kinase | DDB0230010.AA | S_TKc | 935-1193 | 30 | 1.1e-76 | 261.97 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 935-1193 Range on HMM: 1-231/231 Sequence Identity: 30% (83 aa) FRDKIKLGTGAFGNVFYAIRKSDSSPVAIKVLMERTKKDSPIIPELYIHSACNHSNIVTYIESYLCKGHVWIILEYCDG--GTVRDLLQATCTPGNPNNL .. |.| |||| |. .. |.. ||||.. |. |. |.. .| |||...... .|.....||||| |...|... ..|.. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR--- QLFEETLIAYIITELLEGLVYLRSKGIIHRDLKSRNILLTRKGKVKIADFGLATTCSLGRGRTRMCGTMGRIAPEVIRREPYDT-QSDIYSLGCLIIEMA . | | ..... .....| |. |.|||||||| ||||.. .||.|||||. | .||| .||||. .|.. .|..|.||...||. FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML EGTVPYGKDSSLKALFYTAIHQYKLPNPKKYTKEFVDFLYLCLNPDPFKRPTPEMLLH-------HTFL | |. ....| ..|. ||. ||. || |||| .|. | .. CGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | DDB0230010.AA | Pkinase | 935-1193 | 28 | 6.1e-72 | 250.12 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 935-1193
Range on HMM: 1-293/293
Sequence Identity: 28% (87 aa)
FRDKIKLGTGAFGNVFYAIRKSDSSPVAIKVLMERTKKDSPIIP-----ELYIHSACNHSNIVTYIESYLCKGHVWIILEYCDGG----TVRDLLQATCT
.. . |.| |.|| |. ...|... ||.|.. |..|.. . |..|. .|| |||...... |.|.....|||.|| |....
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST---
PGNPNNLQLF--EETLIAYIITELLEGLVYLRSKGIIHRDLKSRNILLTRKGKV----KIADFGLATT--CSLGRGRTRMCGTMGRIAPEVIR-REPYDT
. | .| . .....|.|| |. |.||||||||. |||. ..| . ||.||||| .. | ||| . .|||||| ...|..
----WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGP
QSDIYSLGCLIIEMAEGTVPYGKD------SSLKALFYTAIHQYKLPNPKKYT-------------------KEFVDFLYLCLNPDPFKRPTPEMLLHHT
.|..|.||...||. | |. . . .. .. . ... . |.... .|. ||.. ||..|| ||||.| .|.|
KVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHP
FL
..
WF
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| Kinase | DDB0230010.AA | PAKA | 935-1193 | 40 | 7.1e-71 | 241.78 | In-house | 1-260 (260) | Show / Hide |
Range on Protein: 935-1193
Range on HMM: 1-260/260
Sequence Identity: 40% (106 aa)
FRDKIKLGTGAFGNVFYAIRKSDSSP--VAIKVL-MERTKKDSPIIPELYIHSACNHSNIVTYIESYLCKGHVWIILEYCDGGTVRDLLQATC-TPGNPN
.. |.| || | |. |.... . ||||.. |. | || |. . |.| ||| ||.||| . |...|| .|| |.....| . |
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCN--
NLQLFEETLIAYIITELLEGLVYLRSKGIIHRDLKSRNILLTRKGKVKIADFGLATTCSL-GRGRTRMCGTMGRIAPEVIRREPYDTQSDIYSLGCLIIE
..| |||.. | | || .. ||..||||.|| |||| |.|||.||| .. . . |. | || ||||||| || || ||| ..||
---YMDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIE
MAEGTVPYGKDSSLKALFYTAIH-QYKLPNPKKYTKEFVDFLYLCLNPDPFKRPTPEMLLHHTFL
|.|| || .. |.|... | .. .| | ..|| ||| .||. |. .|.. ..|||| ||
MIEGEPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
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| Kinase | DDB0230010.AA | MKC | 935-1193 | 35 | 8e-61 | 208.39 | In-house | 1-260 (260) | Show / Hide |
Range on Protein: 935-1193
Range on HMM: 1-260/260
Sequence Identity: 35% (96 aa)
FRDKIKLGTGAFGNVFYAIRKS-----DSSPVAIKVLMERTKKD-SPIIPELYIHSACNHSNIVTYIESYLCKG-HVWIILEYCDGGTVRDLLQATCTPG
. . . | |.|| |. | . | . ||||.. ||| | . ||| |||.|. |.. . .|.. |. .||| .. |. .
YKFLHQVGKGGFGTVYCAKYNNPHSTYDKCRVAIKKMPHVTKKHQRNNLNEIGFLNYCNHPNIVKYHCSHMKHDDEIWMVMEFMQGGTLEEASQNSHK--
NPNNLQLFEETLIAYIITELLEGLVYLRSKGIIHRDLKSRNILLTRKGKVKIADFGLATTCSLGRGRTRMCGTMGRIAPEVIRREPYDTQSDIYSLGCLI
| |. |||. |.|.|| || .. |.|||||| || . .|..|. |||| | ... .||| ..|| |. ... . .|| |.| .
-------FCESCIAYVCKEMLQGLMYLHEHNIVHRDLKSANIMMNTDGEIKLIDFGLCIDVSHEKEEIHMCGSPFWMSPEMIQQKQHSYPCDIWSFGICL
IEMAEGTVPYGKDSSLKALFYTAIHQYKLP----NPKKYTKEFVDFLYLCLNPDPFKRPTPEMLLHHTFL
||| | .|. ..|..|| |..|. |.| | . . .| ||| .|| || ||||.| || | |.
LEMANGRPPH-HKSRMKAMFMVATNGCKFPKEFDDPCHWSDCFHDFLWQCLQMDPHKRPTAEQLLKHPFI
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| Kinase | DDB0230010.AA | KHS | 935-1193 | 35 | 4.8e-54 | 180.1 | In-house | 1-258 (258) | Show / Hide |
Range on Protein: 935-1193 Range on HMM: 1-258/258 Sequence Identity: 35% (95 aa) FRDKIKLGTGAFGNVFYAIRKSDSSPVAIKVL-MERTKKDSPIIPELYIHSACNHSNIVTYIESYLCKGHVWIILEYCDGGTVRDLLQATCTPGNPNNLQ . ..|.| .|.|. | .. .. .|.||. || . | |. . | |.||| |. ||| . ..||..||| || . |. ..| YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVTGP-------- LFEETLIAYIITELLEGLVYLRSKGIIHRDLKSRNILLTRKGKVKIADFGLAT--TCSLGRGRTRMCGTMGRIAPEVI---RREPYDTQSDIYSLGCLII .| |||. | |.|| || |.| .|||.| ||||| .|.||.||||... | .... | || .|||| |. |. . ||...| | -LSELQIAYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAK-RKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAI EMAEGTVPYGKDSSLKALFYTAIHQY---KLPNPKKYTKEFVDFLYLCLNPDPFKRPTPEMLLHHTFL |.|| | ..||| . .. || . .|... | .|. ..| .| ||||.| ||.|.|. ELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV |
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| Kinase | DDB0230010.AA | Ciliate-E2 | 935-1193 | 21 | 4.3e-53 | 180.6 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 935-1193 Range on HMM: 1-365/365 Sequence Identity: 21% (80 aa) FRDKIKLGTGAFGNVFYAIR-----------------------KSDSSPVAIKVLMER----TKKDSPII----------PELYIHSACNHSNIVTYIES . |.|.|.|| |... . | ... .|.|..... .|. |. |. | . || ||. ..|. YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC YL--CKGHVWIILEYCDGGTVRDLLQATCTPGNPN----------NLQLFEETLIA-------YIITELLEGLVYLRSKG-IIHRDLKSRNILLTRKGKV . . .. ...|||.||. .|... .. | . . . . .. ..|......| || ||. |||||.| |||. . FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I KIADFGLATTCSLGRGRTRM--------------------------------CGTMGRIAPEVIRREP---------YDTQSDIYSLGCLIIEMAEGTVP ||.||||.. .. . .... ||| | |||...... ||...||.|||... || | | KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP YGKDSSLKALFYTAIHQYKLP------------------NPKKYTKEFVDFLYL----CLNPDPFKRPT-PEMLLHHTFL . . |.| |. ..|| ..| |.. .|. || ||.| .| .| | .. F----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | DDB0230010.AA | STE11 | 935-1193 | 31 | 2e-52 | 180.46 | In-house | 1-303 (303) | Show / Hide |
Range on Protein: 935-1193
Range on HMM: 1-303/303
Sequence Identity: 31% (97 aa)
FRDKIKLGTGAFGNVFYAIRKSDSSPVAIKVLMERTKKD---------SP------IIPELYIHSACNHSNIVTYIESYL-C--KGHVWIILEYCDGGTV
.. . ..|.|||| |. .. .. .|.| ... . .. | |. ... || ||| |. . | . ..|| |..||| ||..
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSL
RDLLQATCTPGNPNNLQLFEETLIAYIITELLEGLVYLRSKGIIHRDLKSRNILLTRKGK-VKIADFGLATTCS-LGRGRTR----------MCGTMG--
...|. |.. |.|..| . .. .|||| || |.||||||.| |||| .| .|.|||| |. . .. . | ||
SSMLRHKWGPMK------FDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNS
------RIAPEVIRREP---YDTQSDIYSLGCLIIEMAEGTVPY-GKDS-SLKALFYTAIH-QYKLPNPKKYT------KEFVDFLYLCLNPDPFKRPTP
|||||..|. |....|| |||| .|||| | |. . |. . |.|. . . . | | . . | ||| .|. .|| ||||
MMGTPMWMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTA
EMLLHHTFL
|| | |.
NQLLQHPFI
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| Kinase | DDB0230010.AA | TKL | 941-1191 | 18 | 1.9e-49 | 170.62 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 941-1191
Range on HMM: 1-364/364
Sequence Identity: 18% (69 aa)
LGTGAFGNVFYAIRKSDS--------SPVAIKVLMER------------------------TKKDSPIIPELY----IHSACNHSNIVTYIESYLCKGH-
.| |.|| |. .. . . .||.|.. .. .. | . .. ..| ..| ||| .. . .| ..
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG
------------VWIILEYCDGGTVRDLLQATCTPGNPNNLQLFEETLIAYIITELLEGLVYLRS--------KGIIHRDLKSRNILLTRKGK-------
.|. |||.||. ...|. .. .. . |. || | ..||||||||.|||. ....
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMY
-------VKIADFGLATTCSLGRG--------------------RTRMCGTMGRIAPEVIRRE----------------PYDTQSDIYSLGCLIIEMAEG
.||.||||... | . . . ||| . ||||.| . .|....|.|| | .. |.. .
NPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTR
TVPYGKDSSLKAL---------FYTAIHQYKLPNP------------KKYTKEFVDFLYLCLNPDPFKRPTPEMLLHHT
.|| .. . . . . .....| | . ... . . | ..|| |||. . .|..
CRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
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| Kinase | DDB0230010.AA | PAKL | 935-1133 | 38 | 2.3e-41 | 143.73 | In-house | 1-195 (256) | Show / Hide |
Range on Protein: 935-1133 Range on HMM: 1-195/256 Sequence Identity: 38% (78 aa) FRDKIKLGTGAFGNVFYAIRKSDSSPVAIKVL-MERTKKDSPIIPELYIHSACNHSNIVTYIESYLCK-GHVWIILEYCDGGTVRDLLQATCTPGNPNNL | . |||.|..| |. || |. | ||||. . . .| | | |. ||| | | | | || ..|| | ..|... .| FEFQEKLGQGSYGSVYKAIHKDTNFPLAIKVIEIKESNEIKDIEKEIQILKKCKCPNIVSYFGSIQQKLNHYWILMDYCSLGSINDMMESCC-------- QLFEETLIAYIITELLEGLVYLRSKGIIHRDLKSRNILLTRKGKVKIADFGLATTCSLGRG--RTRMCGTMGRIAPEVIRREPYDTQSDIYSLGCLIIEM ..| |. |. | ||.|| ||.||||| |. ||||. . ||||||| . | || |||.| . .|. || ||| .||| KTLNEKQISVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMAPEIINKQNYNNKCDIWSLGITAIEM AEG |.| ADG |
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| Kinase | DDB0230010.AA | Pkinase_Tyr | 935-1183 | 29 | 2.1e-28 | 96.85 | Pfam | 1-262 (270) | Show / Hide |
Range on Protein: 935-1183 Range on HMM: 1-262/270 Sequence Identity: 29% (79 aa) FRDKIKLGTGAFGNVFYAIRK----SDSSPVAIKVLMERTKKD----SPIIPELYIHSAC-NHSNIVTYIESYLCK-GH--VWIILEYCDGGTVRDLLQA . ||| ||||.|. .. | .. |||.|.| | . .. . |. | . .| ||| .. ... .. ..|..||. .| .| |.. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK TCTPGNPNNLQLFEETLIAYIITELLEGLVYLRSKGIIHRDLKSRNILLTRKGKVKIADFGLATT--------CSLGRGRTRMCGTMGRIAPEVIRREPY . .. | . . . .. .|. || ||..||||| ||.|.|....|||.||||| . . | |. . |||.|. . HR-----EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWM----APECINYGKF DTQSDIYSLGCLIIEMAE-GTVP-YGKDSSLKALFYTAIHQYKLPNPKKYTKEFVDFLYLCLNPDPFKRPT |.||..| | |. |. | | | | . | . . | .| |.. ..| | . .| ..|| .||| TTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPT |
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| Kinase | DDB0230010.AA | STE-Unique | 936-1002 | 33 | 2.7e-27 | 93.63 | In-house | 264-337 (616) | Show / Hide |
Range on Protein: 936-1002 Range on HMM: 264-337/616 Sequence Identity: 33% (25 aa) RDKIKLGTGAFGNVFYAIRKSDSSPVAIKVLMERTKKD-------SPIIPELYIHSACNHSNIVTYIESYLCKG ......|.|.||||.....|.|....||||......|| ..||.|..|.....|.|||.|....|..| NCQQMIGRGSFGNVHNCQNKKDCFRCAIKVIHLKQFKDFNQEPLVNMIISEIEIMKCLHHQNIVKYYGHWLWGG |
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| Kinase | DDB0230010.AA | TyrKc | 935-1192 | 24 | 3.5e-20 | 74.31 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 935-1192
Range on HMM: 1-280/280
Sequence Identity: 24% (73 aa)
FRDKIKLGTGAFGNVFYAIRKSDSSPVAIKVLMERTKKDSPIIPELYIHSAC--NHSNIVTYIESYLCK-------GHVWIILEYCDGGTVRDLLQATCT
. . ||| |||| |. .. | .||.|.| | . .. |. | . .| ||| . . . . ..|..||...| .| |...
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP
PGNPNNLQLFEETLIAYIITELLEGLVYLRSKGIIHRDLKSRNILLTRKGKVKIADFGLATTCSLG-----RGRTRMCGT--MGR-------IAPEVIRR
. .. . .| || ||..||||| ||.|..... |||.||||. . .. . . . |. |||.|.
K--------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY
EPYDTQSDIYSLGCLIIEMAE-GTVPYGKD----SSLKALFYTAIHQYKLPNPKK--------YTKEFVDFLYLCLNPDPFKRPTPEMLLHHTF
. |.||..| | .. |. | || . | . .. . | .| |. ..| . | . || .||| . . |. |
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
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| Kinase | DDB0230010.AA | PAKL | 1155-1193 | 43 | 4.9e-10 | 33.86 | In-house | 218-256 (256) | Show / Hide |
Range on Protein: 1155-1193 Range on HMM: 218-256/256 Sequence Identity: 43% (17 aa) KLPNPKKYTKEFVDFLYLCLNPDPFKRPTPEMLLHHTFL .. |||.. ..|.||| |. || ||. | || | |. TFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI |
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