Gene MkcA (Slime mold)

MkcA

Species: Slime mold
Alias: MkcA, DDB0191179, DdisK157
External Links: DictyBase Link ,
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: MKC

Sequence

Name Sequence Type Origin Length Description Download
MkcA.AA Protein None 860 None Fasta, JSON
MkcA.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of MkcA.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MkcA.AA MKC 585-836 60 3.1e-204 684.78 In-house 1-260 (260) Show / Hide 
Range on Protein: 585-836
Range on HMM: 1-260/260
Sequence Identity: 60% (158 aa)

YTFREKVGKGGFGTVYLVRNNM---DKSKSRIAIKKLPHVRKKEKKFNVKEIRVLEFTNHPNIITYYNSHMLHD-EVWIAMEFMEGGTLAEASNQ-YPFQ
|.|...||||||||||....|.   ...|.|.||||.|||.||....|..||..|...|||||..|..|||.|| |.|..||||.||||.|||.. ..|.
YKFLHQVGKGGFGTVYCAKYNNPHSTYDKCRVAIKKMPHVTKKHQRNNLNEIGFLNYCNHPNIVKYHCSHMKHDDEIWMVMEFMQGGTLEEASQNSHKFC

ESNIAYVAREVLQGLAYLHGIQLVHRDLKSQNIMMTTSGEIKLIDFGLCANLSK-GERIRMCGSPIWMPPEMIQQKQHGYTCDIWSTAICLLELANRNNK
||.||||..|.||||.|||....|||||||.||||.|.|||||||||||...|. .|.|.|||||.||.|||||||||.|.|||||..|||||.||....
ESCIAYVCKEMLQGLMYLHEHNIVHRDLKSANIMMNTDGEIKLIDFGLCIDVSHEKEEIHMCGSPFWMSPEMIQQKQHSYPCDIWSFGICLLEMANGRPP

LRKNPIKTMFMVGSEGIKDP--FEDPHKWSDEFHDIINKCLQMDPHKRPSAQELLKHPFI
..|...|.||||...|.|.|  |.||..|||.|||....||||||||||.|..|||||||
HHKSRMKAMFMVATNGCKFPKEFDDPCHWSDCFHDFLWQCLQMDPHKRPTAEQLLKHPFI
Kinase MkcA.AA STE20 585-836 40 1.8e-127 429.79 In-house 1-288 (288) Show / Hide 
Range on Protein: 585-836
Range on HMM: 1-288/288
Sequence Identity: 40% (117 aa)

YTFREKVGKGGFGTVYLVRNNMDKSK--SRIAIKKLPHVRK----KEKKFNVKEIRVLEFTNHPNIITYYNSHMLH----DEVWIAMEFMEGGTLAEASN
|.. ||.|.|..|.||.....  . .  .|.||||...  .    .|.. ..|||...   .||||..||.|.. .    || ||.||...||.| .. .
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

QY----------PFQESNIAYVAREVLQGLAYLHGIQLVHRDLKSQNIMMTTSGEIKLIDFGLCANLSK-------GERIRMCGSPIWMPPEMIQQ----
..          |..|. |||. |||||||.|||  . .|||.|..||..|..||.||.|||.|| |.|       ..|  ..|.| || ||.||.    
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP

-KQHGYTCDIWSTAICLLELANRNNKLRK-NPIKTMFMVGSEGIKDP-FED--PHKWSDEFHDIINKCLQMDPHKRPSAQELLKHPFI
 |...| |||||  |...|.|...  ... .| . |||. ... . | ..|  |||||.|||| ..||||.||.|||.|..|||||||
DKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase MkcA.AA STE 585-836 30 1.4e-103 350.46 In-house 1-359 (359) Show / Hide 
Range on Protein: 585-836
Range on HMM: 1-359/359
Sequence Identity: 30% (112 aa)

YTFREKVGKGGFGTVYLVRNNM-----DKSKS--------RIAIKKLPHVRK-----------------KEKKFNVKEIRVLEFTN--HPNIITYYNSHM
... ||.|||.|||||. .|.      .. .         ..|||.... ..                 .|..   |||...   |  ||||..|| ...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

LH-------DEVWIAMEFMEGGTLAEASN---------------QYPFQESNIAYVAREVLQG-LAYLHGIQLVHRDLKSQNIMMTTSGEIKLIDFGLCA
         ||.||.||.|.||.| .  .               | .|.|| |||..|..|.| |.|||  . .|||.|..||..     .||.|||.|.
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

NLSK------------------GERIRMCGSPIWMPPEMIQQ------KQHGYTCDIWSTAICLLELANRNNKLRK-NPIKTMFMVGSEG----------
.|..                  ..|  ..|.| || ||.|||      |.... |||||  ....|.|. .  . . .| . |||   ..          
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

--------IKDPFED-------------PHKWSDEFHDIINKCLQMDPHKRPSAQELLK--HPFI
        ..|....             |||||.||.| ||||||.||.|||.|..|||  ||||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase MkcA.AA S_TKc 585-836 28 5.9e-86 292.78 SMART 1-231 (231) Show / Hide 
Range on Protein: 585-836
Range on HMM: 1-231/231
Sequence Identity: 28% (78 aa)

YTFREKVGKGGFGTVYLVRNNMDKSKSRIAIKKLPHVRKKEKKFNVKEIRVLEFTNHPNIITYYNSHMLHDEVWIAMEFMEG--GTLAEASNQYP-----
|.. .|.|||.||.||..|..   .. . |||...       .   .||..|.  .||||...| .    |.... ||...|  |.| .   ...     
YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--FQESNIAYVAREVLQGLAYLHGIQLVHRDLKSQNIMMTTSGEIKLIDFGLCANLSKGERIRMCGSPIWMPPEMIQQKQHGY-TCDIWSTAICLLELAN
  | |  ...........|.|.|  . .||||| .||....  .||..||||.. |       .||.| .|.||..   ..|.  ||.||  ..| |.. 
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

RNNKLRKNPIKTMFMVGSEGIKDPFEDPHKWSDEFHDIINKCLQMDPHKRPSAQELLK-------HPFI
.    . .. ... ..|              |.|. |.|.||||.|| |||.| |.|.       ||..
GYPPFP-QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase MkcA.AA PAKA 585-836 40 7.7e-82 278.19 In-house 1-260 (260) Show / Hide 
Range on Protein: 585-836
Range on HMM: 1-260/260
Sequence Identity: 40% (105 aa)

YTFREKVGKGGFGTVYLVRNNMDKSKSRIAIKKLPHVRKKEKK-FNVKEIRVLEFTNHPNIITYYNSHMLHDEVWIAMEFMEGGTLAEASNQYP------
|.|.||.|.|. |.||.. |   .... .|||..  . .  ||   . ||.|.   .|.||. |. |. . || |..||.|||| | .   |.       
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQM-NMKNQPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCNY

FQESNIAYVAREVLQGLAYLHGIQLVHRDLKSQNIMMTTSGEIKLIDFGLCANLSK--GERIRMCGSPIWMPPEMIQQKQHGYTCDIWSTAICLLELANR
..|. |||| ||.|||| ..|  . .|||.|| || . . |..|. ||| ||.|..   .|  | | | || || |..|| ..  ||||. | ..|..  
MDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIEMIEG

N-NKLRKNPIKTMFMVGSEGIKDPFEDPHKWSDEFHDIINKCLQMDPHKRPSAQELLKHPFI
    |. .| . |. . ..| | .. ||.|||.||.|  .|||..|. .|.||||||.|||.
EPPYLNEPPLRAMYLIATNG-KPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase MkcA.AA Pkinase 585-836 26 5e-71 247.08 Pfam 1-293 (293) Show / Hide 
Range on Protein: 585-836
Range on HMM: 1-293/293
Sequence Identity: 26% (78 aa)

YTFREKVGKGGFGTVYLVRNNMDKSKSRIAIKKLPHVRKKEKKF--NVK--EIRVLEFTNHPNIITYYNSHMLHDEVWIAMEFMEGG----TLA---EAS
|.. .|.|.|.||.||. ..  .    . |.|... ...|..|   ...  ||...   |||||...| . . .|.... ||..|||     |.   ...
YHIGRKIGSGSFGCVYKCHHKGTGK--IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

NQYPF--QESNIAYVAREVLQGLAYLHGIQLVHRDLKSQNIMMTTSGEI----KLIDFGLCA---NLSKGERIRMCGSPIWMPPEMIQ-QKQHGYTCDIW
.. .|  .|  .  .....|.||.|.|    .|||||..||..   |.|    |..||||..   . ...     ||.| .|.|| |. .. .|. .|.|
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

STAICLLELANRNNKLR-K------NPIKTMFMVGSEGIKDPFEDP-----------------HKWSDEFHDIINKCLQMDPHKRPSAQELLKHPFI
|  . | |.....   . .      .... ......  .. ... .                 |.||.|. |.|..||..||.|||.|...|.||..
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase MkcA.AA KHS 585-836 35 9.4e-59 196.19 In-house 1-258 (258) Show / Hide 
Range on Protein: 585-836
Range on HMM: 1-258/258
Sequence Identity: 35% (92 aa)

YTFREKVGKGGFGTVYLVRNNMDKSKSRIAIKKLPHVRKKEKKFNVKEIRVLEFTNHPNIITYYNSHMLHDEVWIAMEFMEGGTLAEASNQY-PFQESNI
|    .|| | .| ||  |.   .. . . . |.      . .   .|| ..    ||||. |. | . .| .||.||.  || | .      | .|  |
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKM--EPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVTGPLSELQI

AYVAREVLQGLAYLHGIQLVHRDLKSQNIMMTTSGEIKLIDFGLCANLSK--GERIRMCGSPIWMPPEMIQ-QKQHGYT--CDIWSTAICLLELANRNNK
|||.||.||||.|||  . .|||.|  ||..| .|..|| |||. |...   . |    | | || ||.   ... ||   ||||.. |  .|||     
AYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAELQPP

LRK-NPIKTMFMVGSEGIKDP-FEDPHKWSDEFHDIINKCLQMDPHKRPSAQELLKHPFI
.    |.. .|..   . . |  .| ||||. ||. .  .|  .| |||.|. ||.|||.
MFDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase MkcA.AA CAMK 590-764 18 1.5e-42 134.48 In-house 1-319 (425) Show / Hide 
Range on Protein: 590-764
Range on HMM: 1-319/425
Sequence Identity: 18% (60 aa)

KVGKGGFGTVYLVRNNMDKSKSR----------IAIKKLP----------------------------HVRKKEKKFNVKEIRVLEF-------TNHPNI
. |.|.||.|.|...  .. | |           ||| ..                            ..| | .|.  .||...          .||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

ITYY----------------NSHM-LHDE----VWIAM---EFMEGG----TLAEASNQ----------------YPFQESNIAYVAREVLQGLAYLHGI
|  |                .  .    .    ... |   |...||     | .   .                  |.|.  ... | ......|.|  
IKLYEVYEDPHYFKNTNDYET-SKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSH

QLVHRDLKSQNIMMTTS-----------------GEIKLIDFGLCANLSKGERIR-------------------------MCGSPIWMP-PEMIQQKQ--
  ||||||  ||.....                 . ||.||||. . . .||  .                         .||.|  |. ||....|.  
NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

------------HGYTCDIWS
            .|. ||.||
NMQNATDEEKPYYGPKCDMWS
Kinase MkcA.AA Ciliate-E2-Unclassified 585-764 23 3.1e-42 144.3 In-house 1-255 (352) Show / Hide 
Range on Protein: 585-764
Range on HMM: 1-255/352
Sequence Identity: 23% (61 aa)

YTFREKVGKGGFGTVYLVRNNMDK--------SKSRIAIKKLPHVRKKEKKFNVKEIRVL--------------EFTNHPNIITYYNSHMLHDE--VWIA
|.. .. |.||||.||..... .|        .|..|  .|.    . |.... ||.  .              .. |||... ..  ..  |.  . | 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEFMEGGTLAEASNQ------------------YPFQESNIA-----YVAREVLQGLAYLHGIQ-LVHRDLKSQNIMMTTSG---EIKLIDFGLCA----
||..|||.| .  ..                    |.| ...     . ....|||| |||  .  .|||.| .||... .|   .||.||||..     
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

-------------NLSKGERIRMCGSPIWM----PPEMIQQKQHG----YTCDIWS
             .... .   .||.|. |    .||..|.....    | |||||
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWS
Kinase MkcA.AA Ciliate-E2 585-764 23 6.1e-40 134.78 In-house 1-281 (365) Show / Hide 
Range on Protein: 585-764
Range on HMM: 1-281/365
Sequence Identity: 23% (67 aa)

YTFREKVGKGGFGTVYLVRNNMDK---------------------SKSRIAIKKLPHVRKKEKKFNVKEIR-------------VLEFTNHPNIITYYNS
| | .| |.|.||.||....  ..                      .. .|.| . .  ....|   ...|             .||. |||||| .| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

HMLHDE--VWIAMEFMEGGTLAE-------ASNQY-----PFQESNIAYVAREVLQ---------------GLAYLHGIQ-LVHRDLKSQNIMMTTSGEI
    |.  . . ||. .||.| .        .|.      .| |  |.|. ...||               .| |||     .|||.| .||..     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLIDFGLCANLSKGERIRM---------------------------------CGSPIWMPPEMIQ---------QKQHGYTCDIWS
|.|||||. .... .  |                                  ||.|  |.||...         ||...| |||||
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWS
Kinase MkcA.AA PAKB 584-772 39 1.5e-39 137.76 In-house 1-188 (252) Show / Hide 
Range on Protein: 584-772
Range on HMM: 1-188/252
Sequence Identity: 39% (76 aa)

LYTFREKVGKGGFGTVYLVRNNMDKSKSRIAIKKLPHVRKKEKK---FNVKEIRVLEFTNHPNIITYYNSHMLHDEVWIAMEFMEGGTLAEASNQYPFQE
|  .  |.| |  |.| . ..    ..  .|.||.   ||       ||  |. ..    ||||.  |.|..  || |. ||||||| |     .   .|
LDNY-VKIGEGSTGIVCIATEKH--TGRQVAVKKM-DLRKQQRRELLFN--EVVIMRDYQHPNIVEMYSSYLVGDELWVVMEFMEGGALTDIVTHTRMNE

SNIAYVAREVLQGLAYLHGIQLVHRDLKSQNIMMTTSGEIKLIDFGLCANLSKG--ERIRMCGSPIWMPPEMIQQKQHGYTCDIWSTAICLLEL
  ||.| | ||| |||||    .||| ||  |..|  | .|| ||| || .||    |  . | | || ||.|     |   ||||  | ..|.
EQIATVCRQVLQALAYLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEM
Kinase MkcA.AA STE11 585-764 30 3.5e-39 136.48 In-house 1-223 (303) Show / Hide 
Range on Protein: 585-764
Range on HMM: 1-223/303
Sequence Identity: 30% (68 aa)

YTFREKVGKGGFGTVYLVRNNMDKSKSRIAIKKLPHVRKK------EKKFNV--------KEIRVLEFTNHPNIITYYNSHM---LHDEVWIAMEFMEGG
.. .|. ||| |||||. .|   .   ..|.|. . .. .      ||. .         .||....  ||.||. || .       |.| | ||...||
WQKGEIIGKGAFGTVYKCMNV--DTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGG

TLAEASN-QY-P--FQESNIAYVAREVLQGLAYLHGIQLVHRDLKSQNIMMTTSGE-IKLIDFGLCANLS-------------------KGERI-RMCGS
.|..  .  . |  |.|. | .  . .|.||.|||  . .|||.|  ||.. . |  .||.||| .  |.                   .|.    | |.
SLSSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGT

PIWMPPEMIQQKQ---HGYTCDIWS
| || ||.| | .   .|  .||||
PMWMAPEVIKQEGRDGYGRKADIWS
Kinase MkcA.AA TyrKc 585-836 22 3.3e-17 55.62 SMART 1-280 (280) Show / Hide 
Range on Protein: 585-836
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

YTFREKVGKGGFGTVYLVRNNMDKSKSRIAIKKLPHVRKKEKKFNVKEIRVLEFT--NHPNIITYYNSHMLH-------DEVWIAMEFMEGGTLAEA--S
 |. .| | | ||.||. . .        |.|.| .    .. |  .|.|..     .||||.  |   . .       . ..| ||.|..| | .   .
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA--REDF-MREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

NQYPFQESNIAYVAREVLQGLAYLHGIQLVHRDLKSQNIMMTTSGEIKLIDFGLCANLSKG-------ERIRM----CG---SPI-WMPPEMIQQKQHGY
..  .. .   . .  . .| .|||  ...||||   |.. .  . .|  ||||. ..  .       . .|.    .|    || ||.|| |. .    
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

TCDIWSTAICLLELANRNNKLR-------KNPIKTMFMVGSEGIKDPFED--PHK----WSDEFHDIINKCLQMDPHKRPSAQELLKHPFI
  |.||  .|. |.  .  .         ....  .  | . .  .. ..  |       .|| ..|. .| . ||..||. .|.  | ..
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase MkcA.AA STE11 782-836 36 3.2e-15 51.72 In-house 244-303 (303) Show / Hide 
Range on Protein: 782-836
Range on HMM: 244-303/303
Sequence Identity: 36% (22 aa)

NPIKTMFMVGSEGIKDPFEDPHKWS------DEFHDIINKCLQMDPHKRPSAQELLKHPFI
|..  || .|.   | . . | . |      .| .|....|.. ||.|||.|..||.||||
NHMAAMFKIGMG-HKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQHPFI
Kinase MkcA.AA CAMK 799-836 24 1.1e-12 36.48 In-house 364-425 (425) Show / Hide 
Range on Protein: 799-836
Range on HMM: 364-425/425
Sequence Identity: 24% (15 aa)

FE-DPHKWSD-----------------------EFHDIINKCLQMDPHKRPSAQELLKHPFI
.. .|...|.                       |  | |.|.|| || ||..... |.||..
YDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase MkcA.AA Ciliate-E2 793-836 33 8.7e-12 36.73 In-house 311-365 (365) Show / Hide 
Range on Protein: 793-836
Range on HMM: 311-365/365
Sequence Identity: 33% (19 aa)

EGIKDPFE-------DPHKWSDEFHDIINK----CLQMDPHKRPS-AQELLKHPFI
| .|| .        ...|||.|  |.|.|    .|| || ||.. ....|.||..
EWQKD-TQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase MkcA.AA Pkinase_Tyr 585-764 27 2.6e-11 38.95 Pfam 1-199 (270) Show / Hide 
Range on Protein: 585-764
Range on HMM: 1-199/270
Sequence Identity: 27% (54 aa)

YTFREKVGKGGFGTVYLVRNN--MDKSKSRIAIKKL-PHVRKKE---KKFNVKEIRVLEFT-NHPNIITYYNSHM-LHDE--VWIAMEFMEGGTLAE--A
 || .| |.| ||.||. . .  .|. |   |.|.| ..  ...   ..|   |....    .||||. .|   .   .   ..| ||.|..| | .   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

SN---QYPFQESNIAYVAREVLQGLAYLHGIQLVHRDLKSQNIMMTTSGEIKLIDFGLCANLSKGERI-RMCG---SPI-WMPPEMIQQKQHGYTCDIWS
..   . |.  . .   .... .|..||. ....||||   |.. | .. .|  ||||.  . . .   |. |    || ||.|| |. .      |.||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS
Kinase MkcA.AA Ciliate-E2-Unclassified 801-836 37 7.9e-11 33.82 In-house 313-352 (352) Show / Hide 
Range on Protein: 801-836
Range on HMM: 313-352/352
Sequence Identity: 37% (15 aa)

DPHKWSDEFHDIIN----KCLQMDPHKRPSAQELLKHPFI
.|..||.|  |.||    |.|. .| ||......|.||..
IPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase MkcA.AA PAKB 799-836 39 6.4e-10 32.36 In-house 215-252 (252) Show / Hide 
Range on Protein: 799-836
Range on HMM: 215-252/252
Sequence Identity: 39% (15 aa)

FEDPHKWSDEFHDIINKCLQMDPHKRPSAQELLKHPFI
. . || | . .. ....|  || .| .|||||.|||.
LKNHHKVSPRLREFLDRMLVRDPNQRWTAQELLRHPFL
Kinase MkcA.AA Pkinase_Tyr 802-836 31 0.014312 9.33 Pfam 238-270 (270) Show / Hide 
Range on Protein: 802-836
Range on HMM: 238-270/270
Sequence Identity: 31% (11 aa)

PHKWSDEFHDIINKCLQMDPHKRPSAQELLKHPFI
|.. .|| .|.. .| . || .||. .|.  | ..
PENCPDEIYDLMKQCWHYDPEDRPTFSEI--HEQL