Gene MkcD (Slime mold)

MkcD

Species: Slime mold
Alias: DdisK160, MkcD, DDB0229913
External Links: DictyBase Link ,
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: MKC

Sequence

Name Sequence Type Origin Length Description Download
MkcD.AA Protein None 652 None Fasta, JSON
MkcD.kin_dom Protein Kinase Domain None 258 None Fasta, JSON

Protein domain

Protein domains of MkcD.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MkcD.AA MKC 369-626 60 2.5e-205 688.43 In-house 1-260 (260) Show / Hide 
Range on Protein: 369-626
Range on HMM: 1-260/260
Sequence Identity: 60% (158 aa)

FKNLDFEARGGFGSVFCAKNKNPHSAYDKQMVALKKMPIKTLRHKRMNLSEIGFLKYFNHPNIVKFLCAYQKSNDELWMIMEFLSGGTLKNAASN-FKFC
.|.|.....||||.|.|||..||||.|||..||.||||..|..|.|.||.|||||.|.|||||||..|...|..||.||.|||..||||..|..| .|||
YKFLHQVGKGGFGTVYCAKYNNPHSTYDKCRVAIKKMPHVTKKHQRNNLNEIGFLNYCNHPNIVKYHCSHMKHDDEIWMVMEFMQGGTLEEASQNSHKFC

ERKIAYVCREILQGLDYLHKQNIAHRDLKSANVMVNDKGEIKLIDFGLCIDFSIEKEEINMLGSPSYISPEMINGNPHSLSTDIWSFGICALEMLLGKLP
|..|||||.|.||||.|||..||.||||||||.|.|..|||||||||||||.|.|||||.|.|||...|||||....||...||||||||.|||..|..|
ESCIAYVCKEMLQGLMYLHEHNIVHRDLKSANIMMNTDGEIKLIDFGLCIDVSHEKEEIHMCGSPFWMSPEMIQQKQHSYPCDIWSFGICLLEMANGRPP

YHDSRLKAMVFVATNNLNLP-LLLSTTTSSLEFRDFLTNCLQFDPSKRLTSSQLLQHPFL
.|.||.|||..||||....| ........|..|.|||..|||.||.||.|..|||.|||.
HHKSRMKAMFMVATNGCKFPKEFDDPCHWSDCFHDFLWQCLQMDPHKRPTAEQLLKHPFI
Kinase MkcD.AA STE20 369-626 36 1.4e-118 400.25 In-house 1-288 (288) Show / Hide 
Range on Protein: 369-626
Range on HMM: 1-288/288
Sequence Identity: 36% (105 aa)

FKNLDFEARGGFGSVFCAKNKNPHSAYDKQMVALKKMPIKTL----RHKRMNLSEIGFLKYFNHPNIVKFLCAYQKS---NDELWMIMEFLSGGTLKNAA
...|.   .|..|.|. | ...|   |..|.|| |||....      ...... || ..| ..||||||....|.|.   .||||..||...||.|  . 
YELLEKIGQGSYGKVYKA-YHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIM

SN----------FKFCERKIAYVCREILQGLDYLHKQNIAHRDLKSANVMVNDKGEIKLIDFGLCIDFSI-----EK-EEINMLGSPSYISPEMING---
..          ... |  |||.|||.||||||||...| |||.|..|......||.||.|||.| ...      .. .  .. |.| . .||.|..   
KHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEG

--NPHSLSTDIWSFGICALEMLLGKLPYHD-SRLKAMVFVATNNLNLPLLLS--TTTSSLEFRDFLTNCLQFDPSKRLTSSQLLQHPFL
  ...   .||||.||.|.||. |. ||.| ....||  ...|.   | | .  ... | ||.||. .||| ||.|| |.||||.|||.
PDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase MkcD.AA STE 369-626 27 7.1e-100 338.1 In-house 1-359 (359) Show / Hide 
Range on Protein: 369-626
Range on HMM: 1-359/359
Sequence Identity: 27% (100 aa)

FKNLDFEARGGFGSVFCAKNKNPHSAY----------DKQMVALKKMPIKTL-----------------RHKRMNLSEIGFLKYFN--HPNIVKFLCAYQ
......  .|.||.|..|.|....  .           ....| |.|....                    .   | || ..| .|  ||||||....| 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KS------NDELWMIMEFLSGGTLKNAASN---------------FKFCERKIAYVCREILQG-LDYLHKQNIAHRDLKSANVMVNDKGEIKLIDFGLCI
|       .||||..||...||.|     .               ..| |  |||.||.||.| |.|||...| |||.|.||...     .||.|||.| 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

DFSIE-----------------KEEINMLGSPSYISPEMING------NPHSLSTDIWSFGICALEMLLGKLPYHD-SRLKAMVFVATNN----------
 .. .                 ..   . |.| . .||.|..      .... . ||||.|....||. || |.|| . ..||   ..|.          
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---LNLPLLLS-----------------TTTSSLEFRDFLTNCLQFDPSKRLTSSQLLQ--HPFL
    . | | .                 ..  | ||.||. .||| ||.|| |.||||.  |||.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase MkcD.AA S_TKc 369-626 28 9e-87 295.49 SMART 1-231 (231) Show / Hide 
Range on Protein: 369-626
Range on HMM: 1-231/231
Sequence Identity: 28% (78 aa)

FKNLDFEARGGFGSVFCAKNKNPHSAYDKQMVALKKMPIKTLRHKRMNLSEIGFLKYFNHPNIVKFLCAYQKSNDELWMIMEFLSG--GTLKNAASNFK-
.. |.   .|.||.|.....|.     ... ||.|...       .. ..||  ||  .||||||.. ..|   |.|.|.||...|  |.|.    . . 
YEILRKIGKGAFGKVYKCRHKK-----TGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGR

------FCERKIAYVCREILQGLDYLHKQNIAHRDLKSANVMVNDKGEIKLIDFGLCIDFSIEKEEINMLGSPSYISPEMINGNPHSL-STDIWSFGICA
      | |  .......|...|.|.|...| ||||| .|.....  .||..||||.  .        . |.| |..||..   ...  . |.||.|.. 
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

LEMLLGKLPYHDSRLKAMVFVATNNLNLPLLLSTTTSSLEFRDFLTNCLQFDPSKRLTSSQLLQ-------HPFL
 ||| |. |..   ...|  .                | |..||. .|||.||.||.|  ..||       ||..
YEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase MkcD.AA PAKA 369-626 36 6.7e-71 241.85 In-house 1-260 (260) Show / Hide 
Range on Protein: 369-626
Range on HMM: 1-260/260
Sequence Identity: 36% (97 aa)

FKNLDFEARGGFGSVFCAKNKNPHSA-YDKQMVALKKMPIKTLRHKRMNLSEIGFLKYFNHPNIVKFLCAYQKSNDELWMIMEFLSGGTLKNAASNFK--
.|...    |. |.|. |.|.   .       || |.| .|.   | . . ||. .| ..|.|||... .|   .||||..||...|| |    ...   
YKFMEKIGQGASGEVYVATNIKTNQEEN----VAIKQMNMKNQPKKELIINEILVMKECKHKNIVNYIDSYLV-DDELWVVMEYMEGGCLTDVITQCCNI

----FCERKIAYVCREILQGLDYLHKQNIAHRDLKSANVMVNDKGEIKLIDFGLCIDFSIEKEEIN-MLGSPSYISPEMINGNPHSLSTDIWSFGICALE
    . |. |||||||.||||...|.....|||.|| |. ..  |..|. ||| |   . |... | | | | . .|| |...  .   |||| || |.|
QCNYMDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIE

MLLGKLPYHDSR-LKAMVFVATNNLN-LPLLLSTTTSSLEFRDFLTNCLQFDPSKRLTSSQLLQHPFL
|. |  || .   |.||  .||   |  | .....  | ||.|||  ||. |. .| ....||.||||
MIEGEPPYLNEPPLRAMYLIAT---NGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase MkcD.AA Pkinase 369-626 26 1.2e-67 235.88 Pfam 1-293 (293) Show / Hide 
Range on Protein: 369-626
Range on HMM: 1-293/293
Sequence Identity: 26% (81 aa)

FKNLDFEARGGFGSVFCAKNKNPHSAYDKQMVALKKMPIKTLRH--KRMNLS--EIGFLKYFNHPNIVKFLCAYQKSNDELWMIMEFLSGG----TLKNA
.. .    .|.||.|. ...|.     . ..||.|... .. ..  .. ..   ||  .| .||||||.......  .|...|.||.. ||     |.  
YHIGRKIGSGSFGCVYKCHHKG-----TGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDY

AS---NFKF--CERKIAYVCREILQGLDYLHKQNIAHRDLKSANVMVNDKGEI----KLIDFGLCIDF-SIEKEEINML-GSPSYISPEMIN-GNPHSLS
 |   . .|   |. .  ....||.||.|.|...| |||||..|......|.|    |..||||.  |    ..  . . |.| |..|| |. |.... .
ISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

TDIWSFGICALEMLLGKLPYHDS----RLKAMVFVATNNLNLPLLLSTTTSS--------------------LEFRDFLTNCLQFDPSKRLTSSQLLQHP
 |.||.|.   |||.|..|. ..    .   . ..  ...  ||  .  ...                     |..||...||..||.||.|  |.||||
VDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHP

FL
..
WF
Kinase MkcD.AA CAMK 377-626 20 6.3e-64 204.59 In-house 4-425 (425) Show / Hide 
Range on Protein: 377-626
Range on HMM: 4-425/425
Sequence Identity: 20% (85 aa)

RGGFGSVFCAKNKNPHSAYD-------KQMVALKKMPIKTLR---------------------------HKRMNLS-EIGFLKY-------FNHPNIVKF
||.|| |. ...||     .       .| || | .. | |.                           ..| |.  ||  .|         .||||.|.
RGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKL

LCAYQ------------KSND-------ELWMIM---EFLSGGTL----------K-----------NAASNFKFCERKIAYVCREILQGLDYLHKQNIA
. .|.              ..       ...|.|   |. ||| |          .            . ....|.||  ... | |.....|.|..||.
YEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSHNIV

HRDLKSANVMVNDK-----------------GEIKLIDFGLCIDFSIEKEEIN------------------------MLGSPSYIS-PEMING-------
|||||  |....|.                 . ||.||||. . |   ... .                        . |.|.|.. ||..||       
HRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQ

-------NPHSLSTDIWSFGICALEMLLGKLPYHDS----------------RLKAMVFVATNNLNLPLLLSTT-----------------TSSLEFRDF
        ... ..|.|| |.    || |..|. ..                .|. ..  .  .   | .  ..                 . | | .|.
NATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDL

LTNCLQFDPSKRLTSSQLLQHPFL
. ..|| ||.||.| .| |.||..
IRKMLQVDPEKRMTIEQCLNHPWM
Kinase MkcD.AA Ciliate-E2 377-626 22 4.5e-62 211.88 In-house 9-365 (365) Show / Hide 
Range on Protein: 377-626
Range on HMM: 9-365/365
Sequence Identity: 22% (83 aa)

RGGFGSVFCA--KNKNPHSA----------------YDKQMVALKKMPIKTLRHKRMNLSEIG-------------FLKYFNHPNIVKFLCAYQ-KSNDE
.|.||||. .  ....  .|                ......|.| |  . .... . ....               |.  |||||.|.  ..| |... 
QGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDDNN

LWMIMEFLSGGTLKN------AASNFK------FCERKIAYVCREILQ---------------GLDYLHKQN-IAHRDLKSANVMVNDKGEIKLIDFGLC
. ..||...||.|.         .|..      | |..|.|. ..|||               .| |||..| | |||.|  |...     ||.|||||.
IYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLS

IDFSIEKEEINM--------------------------------LGSPSYISPEMINGNP---------HSLSTDIWSFGICALEMLLGKLPYHDSRLKA
 ..... ... .                                .|.| | .||..|| .         .. . ||||.|..  ||| ||.|.       
KKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-------

MVFVATNNLNLPLLL-------------STTTSSLEFRDFLTN----CLQFDPSKRLT-SSQLLQHPFL
.     .....|                |.   |.|  |.. .    .|| ||.||.|  .|.|.||..
QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase MkcD.AA ULK 378-626 23 6.7e-56 192.03 In-house 10-329 (329) Show / Hide 
Range on Protein: 378-626
Range on HMM: 10-329/329
Sequence Identity: 23% (75 aa)

GGFGSVFCAK-NKNPHSAYDKQMVALKKMPIKTLRHKR----------MNLSEIGFLKYFN--------HPNIVKFLCAYQKSND-ELWMIMEFLSGGTL
| || |. .. .|.  . | ...|| |........ |           .  .||  .|  .        ||||||..  .. ||.  ...|||.  ||.|
GSFGKVYKGRNKKTK-D-YVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNGGDL

KNAAS-----------NFKFCERKIAYVCREILQGLDYLHKQNIAHRDLKSANVMVNDK------------GEIKLIDFGLCIDFSIE----KEEINML-
..  .           . .. | ..  ... ||.|. .|||.|| |||.| .|......            | .|. |||..  .. .    . .  .. 
EQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVN

-----GSPSYISPEMINGN----PHSLS-TDIWSFGICALEMLLGKLPYHDSRLKAMV-FVATNNLNLPLLL---------------STTTSSLEFRDFL
     |.| | .|. ..|.    |.. . .||||.|.   ||| || |.  .     .    ....|.|. .               .  . | |..|..
EKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLI

TNCLQFDPSKRLTSSQLLQHPFL
  .||.|...| .  .|..||..
RRMLQYDEKDRISWEELFNHPWF
Kinase MkcD.AA STE11 369-626 28 2.1e-55 190.36 In-house 1-303 (303) Show / Hide 
Range on Protein: 369-626
Range on HMM: 1-303/303
Sequence Identity: 28% (88 aa)

FKNLDFEARGGFGSVFCAKNKNPHSAYDKQMVALKKMPIKTLR------------HKRMNL--SEIGFLKYFNHPNIVKFLCAYQK--SNDELWMIMEFL
..  ..  .| ||.|. . |.. .     ...| |...|.  .            ||   .  .||  .| .||.|||... . .   .||..  .||. 
WQKGEIIGKGAFGTVYKCMNVDTG-----ELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYC

SGGTLKNAAS-NF---KFCERKIAYVCREILQGLDYLHKQNIAHRDLKSANVMVNDKGE-IKLIDFGLCIDFSIEK------EEI-----NMLGSPS---
.||.|.   . ..   || |  | .  . ||.|| |||...| |||.| ||.... .|  .||.||| .  .. .       ...      | |.|    
PGGSLSSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSM

-----YISPEMINGNP---HSLSTDIWSFGICALEMLLGKLPYHDSR---LKAMVFVATN-NLNLPLLLSTT---TSSLEFRDFLTNCLQFDPSKRLTSS
     . .||.|.. .   .. . ||||.| . .||. || |.|.       ||  .... .   |.  . .     | | |||| .|...||.|| |..
MGTPMWMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTAN

QLLQHPFL
|||||||.
QLLQHPFI
Kinase MkcD.AA Ciliate-E2-Unclassified 369-626 21 4.8e-55 189.19 In-house 1-352 (352) Show / Hide 
Range on Protein: 369-626
Range on HMM: 1-352/352
Sequence Identity: 21% (78 aa)

FKNLDFEARGGFGSVFCAKNKNPHSAY-------DKQMVALKKMPIKTLRHKRM--NLSEIG-------------FLKYFNHPNIVKFLCAYQKSNDELW
.| .    .||||.|. ...|.    |       ..|... |..  |  ....    . ..               |. ..||.||| .. . .. . . 
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVK-MFYCFQDKQNIY

MIMEFLSGGTLKNAASNFKF---------------C---ERKIA-----YVCREILQGLDYLHKQN-IAHRDLKSANVMVNDKG---EIKLIDFGLCI--
..||.. ||.|..  ...|.               .   |....     . ...|||||.|||..| | |||.|  |......|   .||.||||...  
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKY

--------------DFSIEKEEINMLGSPSYI----SPEMINGNPHSLS----TDIWSFGICALEMLLGKLPYHDSRLKA-------------MVFVATN
              .. ....   . |.|.|.    .||.. |. .. |     ||||.|... ||| |..|. |   .                 .  |
QQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQN

NLNLPLLLST-------TTSSLEFRDFLT----NCLQFDPSKRLTSSQLLQHPFL
 .. ..  .         ..| |  ||..     .|. .|.||.| .|.|.||..
IKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase MkcD.AA ULK 378-626 23 6.5e-55 188.76 In-house 10-324 (324) Show / Hide 
Range on Protein: 378-626
Range on HMM: 10-324/324
Sequence Identity: 23% (75 aa)

GGFG-SVFCAK-NKNPHSAYDKQMVALKKMPIKTLRHKRMN----------LSEIGFLKYFN---HPN--IVKFLCAYQKSND-ELWMIMEFLSGGTLKN
| ||  |. .. .|. .    .| || |....| .. |  .           .||  .| ..   |||  |||..  .. ||.  ...|||.  ||.|..
GSFGVKVYKGRNKKTNT---QNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCNGGDLEQ

AAS----------NFKFCERKIAYVCREILQGLDYLHKQNIAHRDLKSANVMVNDK------------GEIKLIDFGLCIDFSIEKEEINML--------
             . .. | ..  ... |..|. .|||.|| |||.| .| .....            | .|. |||..  .  . .| .|.        
YIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKR

--GSPSYISPEMINGN----PHSLS-TDIWSFGICALEMLLGKLP---YHDSRLKA------------MVFVATNNLNLPLLLSTTTSSLEFRDFLTNCL
  |.| | .|. ..|.    |.. . .||||.|.   ||| || |   .  . ..             .... ..... |.  .    | |..|..  .|
IKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRML

QFDPSKRLTSSQLLQHPFL
|.|...| .  ....||..
QYDEKDRISWEEIFNHPWF
Kinase MkcD.AA TyrKc 369-626 22 2.2e-17 58.27 SMART 1-280 (280) Show / Hide 
Range on Protein: 369-626
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

FKNLDFEARGGFGSVFCAKNKNPHSAYDKQMVALKKMPIKTLRHKRMNLSEIGFLKYF--NHPNIVKFLCAYQKSN------DELWMIMEFLSGGTLKNA
 . ..   .| || |. .. |        ..|| |..   .   ... ..|.  .. .  .|||||... .  ..       . |...||. ..| ||. 
ITLGKKLGEGAFGEVYKGTWK--------IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

ASNFK--FCERKIAYVCREILQGLDYLHKQNIAHRDLKSANVMVNDKGEIKLIDFGLCIDFSIE------KEEINML---GSPS-----YISPEMINGNP
  . .  .| ..  . |  | .| .|||..|. ||||   |..|.... .|  ||||. |   .      |. . .    |. .       .|| || . 
LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

HSLSTDIWSFGICALEML-LGKLPYHD------SRLKAMVFVATNNLNLPLLL-----STTTSSLEFRDFLTNCLQFDPSKRLTSSQLLQHPFL
 .  .|.||||.|  |.. .|. || .      |   .. .| . .   .        .  . . |  .  . | ..||..| | |..  | ..
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF-VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase MkcD.AA Pkinase_Tyr 377-518 24 8.5e-17 57.51 Pfam 9-160 (270) Show / Hide 
Range on Protein: 377-518
Range on HMM: 9-160/270
Sequence Identity: 24% (38 aa)

RGGFGSVFCAKNKNPHSAYDKQMVALKKM-PIKTLRH--KRMNLSEIGFLKYF-NHPNIVKFLCAYQKSNDE--LWMIMEFLSGGTLKN--AAS---NFK
.| ||.|. .. |      .|. || |.. .  . ..  ... ..|.  .| . .|||||... .  .  .   ....||.  .| |..   .    . .
EGAFGEVYKGTWKG-DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQP

FCERKIAYVCREILQGLDYLHKQNIAHRDLKSANVMVNDKGEIKLIDFGLCID
..   .   |..| .|..||. .|. ||||   |..|.... .|  ||||. |
LTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARD