Gene PakE (Slime mold)

PakE

Species: Slime mold
Alias: DDB0229414, PakE, DdisK169
External Links: DictyBase Link ,
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: PAKL

Sequence

Name Sequence Type Origin Length Description Download
PakE.AA Protein None 926 None Fasta, JSON
PakE.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of PakE.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase PakE.AA PAKL 650-903 64 1.7e-218 732.13 In-house 1-256 (256) Show / Hide 
Range on Protein: 650-903
Range on HMM: 1-256/256
Sequence Identity: 64% (165 aa)

FEFKEKLGQGGYGAVFKVLHRETNFPLAIKVLSITPT-RIKDIEKEIDLLKKCRCPNVLSYYGSISSKLTELWILMDHCAVGSINDMMKICCDTLDEEQI
|||.||||||.||.|.|..|..|||||||||..|... .||||||||..||||.|||..||.|||..||...|||||.|..|||||||..||.||.|.||
FEFQEKLGQGSYGSVYKAIHKDTNFPLAIKVIEIKESNEIKDIEKEIQILKKCKCPNIVSYFGSIQQKLNHYWILMDYCSLGSINDMMESCCKTLNEKQI

AVVTLNVLNGLGYLHSKGIVHLDVKAANILLTEDKQIKIADFGVSQQLQTEYG-QANVYIGSPLYMAPEVILKAPYNSKADIWSLGITLIELAEGRPPNR
.|.....|.||.|||||.|.|.|.|||||||.||.|.||||||||||||.||. |||..||.|..||||.|.|..||.|.||||||||.||.|.|.||..
SVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMAPEIINKQNYNNKCDIWSLGITAIEMADGFPPHY

GLRSMNQLVEIPNMPPPKLSNPKDWSPCFNNFLATCLVKDPVQRPSVIDLLSHDFI
....|.....|||.|||..||||.||||||.|||.|.||||..|.|.||||.|.||
DMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase PakE.AA STE20 650-903 43 1.3e-135 456.81 In-house 1-288 (288) Show / Hide 
Range on Protein: 650-903
Range on HMM: 1-288/288
Sequence Identity: 43% (124 aa)

FEFKEKLGQGGYGAVFKVLHRETNFP----LAIKVLSITP-----TRIKDIEKEIDLLKKCRCPNVLSYYGSISSK---LTELWILMDHCAVGSINDMMK
.|. ||.|||.||.|.|. |..|.       |||.... .      ...||.|||. .|.|..||. .||||   .    .||||.|..|. ||. |.||
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

---ICCD-----TLDEEQIAVVTLNVLNGLGYLHSKGIVHLDVKAANILLTEDKQIKIADFGVSQQLQT----EYG-QANVYIGSPLYMAPEVILK----
   .|.      ...|||||... .|| || ||||..|.| |.||.||||||| ..|.|||||..||..      . . |  .|.| .||||||..    
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP

-APYNSKADIWSLGITLIELAEGRPPNRGLRSMNQLVEIP--NMPPPKLSN--PKDWSPCFNNFLATCLVKDPVQRPSVIDLLSHDFI
  .|..|.||||||||.||.|||.||.. .  |  . .||  ..|||.|..  |. |||.|..|...||.||| .||.. .||.| ||
DKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase PakE.AA STE 650-903 30 1.3e-115 390.37 In-house 1-359 (359) Show / Hide 
Range on Protein: 650-903
Range on HMM: 1-359/359
Sequence Identity: 30% (111 aa)

FEFKEKLGQGGYGAVFKVLHR------ETNFP---------LAIKVLSITP------------------TRIKDIEKEIDLLKKCR--CPNVLSYYGSIS
.|. ||.|.|..| |.| ...      .|..           |||.... .                  . ...|.|||...|||.  .||.  |||.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

SKL------TELWILMDHCAVGSINDMMK---ICCDTLD----------EEQIAVVTLNVLNG-LGYLHSKGIVHLDVKAANILLTEDKQIKIADFGVSQ
 .       .|||| | ... ||. |..|   .| ..|.          |.|||...  .| | | ||||..|.| |.|.|||||     .|..||||. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

QLQTEYG----------------QANVYIGSPLYMAPEVILK------APYNSKADIWSLGITLIELAEGRPPNRGLRSMNQLVEIPNM-----------
||. ..                 . |  .|.| .||||||..       .|. |.||||||.|.||.|.|.||   .  |  . .||..           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----PPPKLSN-----------------PKDWSPCFNNFLATCLVKDPVQRPSVIDLLS--HDFI
    |||.| .                 |. |||.|..|.. ||.||| .||.. .||.  | ||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase PakE.AA MST 650-903 45 4.6e-114 363.97 In-house 1-254 (254) Show / Hide 
Range on Protein: 650-903
Range on HMM: 1-254/254
Sequence Identity: 45% (116 aa)

FEFKEKLGQGGYGAVFKVLHRETNFPLAIKVLSITPTRIKDIEKEIDLLKKCRCPNVLSYYGSIS-SKLTELWILMDHCAVGSINDMMKICCDTLDEEQI
|.  |||||| || |.| .|..|.  .|||....  . . .|.|||  .. |  ...  ||||    | ...|| | .|. ||..|.|||   || |.||
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPV-NEDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLNEQQI

AVVTLNVLNGLGYLHSKGIVHLDVKAANILLTEDKQIKIADFGVSQQLQTEYGQANVYIGSPLYMAPEVILKAPYNSKADIWSLGITLIELAEGRPPNRG
|..  ..| || |||.  ..| | ||.|||| ..   | |||||| ||    . .|  ||.| .|||||| .  |..|||||||||| ||.|||.||   
ACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQEIKYDCKADIWSLGITAIEMAEGMPPYSD

LRSMNQLVEIPNMPPPKLSNPKDWSPCFNNFLATCLVKDPVQRPSVIDLLSHDFI
.. |  .  ||  |||....|  ||. ||.|.. ||.|.| ||..  .||.|.||
IHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase PakE.AA YSK 650-903 42 2.4e-97 293.64 In-house 1-257 (257) Show / Hide 
Range on Protein: 650-903
Range on HMM: 1-257/257
Sequence Identity: 42% (110 aa)

FEFKEKLGQGGYGAVFKVLHRETNFPLAIKVLSITPTR--IKDIEKEIDLLKKCRCPNVLSYYGSISSKLTELWILMDHCAVGSINDMMKI-CCDTLDEE
|   |. | | .| |.|   . |.   |||..        | || .||  |  |  |..  ||||   | | ||| | .|. ||. | ||      .||.
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSY-LKDTKLWIIMEYCGGGSCLDLMKPKYVGQFDEK

QIAVVTLNVLNGLGYLHSKGIVHLDVKAANILLTEDKQIKIADFGVSQQLQTEYGQANVYIGSPLYMAPEVILK--APYNSKADIWSLGITLIELAEGRP
.||..   .| || ||||   .| |.||||.||.|. ..|..||||. |.       |  .|.| .|||||| .    |..|||||||||| .|.| | |
YIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGEP

PNRGLRSMNQLVEIPNMPPPKLSNPKDWSPCFNNFLATCLVKDPVQRPSVIDLLSHDFI
|.  .  |  .  ||  .||||.  ...|  | .| . ||.||| ||||  .||.| ||
PYCDYHPMRVMFLIPKNNPPKLEG-RSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase PakE.AA S_TKc 650-903 30 5.7e-84 286.19 SMART 1-231 (231) Show / Hide 
Range on Protein: 650-903
Range on HMM: 1-231/231
Sequence Identity: 30% (82 aa)

FEFKEKLGQGGYGAVFKVLHRETNFPLAIKVLSITPTRIKDIEKEIDLLKKCRCPNVLSYYGSISSKLTELWILMDHCAV--GSINDMMKICCD-----T
.|. .|.|.|..| |.|. |..|.   |||...      ..|..||..||| ..||.  .|... .  ..|.. |..|    |.  |..| .        
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LDEEQIAVVTLNVLNGLGYLHSKGIVHLDVKAANILLTEDKQIKIADFGVSQQLQTEYGQANVYIGSPLYMAPEVILKAPYNS-KADIWSLGITLIELAE
..| ... ..  ....| |.||.||.| |.| .||||.|  .|||.|||.. ||       . ..|.| ||||||.   .|.  |.|.||.|..|.|.. 
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

GRPPNRGLRSMNQLVEIPNMPPPKLSNPKDWSPCFNNFLATCLVKDPVQRPSVIDLLS-------HDFI
|.|| .    |... ..              || . .|.  ||.||| .||.. ..|        | ..
GYPPFP---QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase PakE.AA MSN 650-903 40 3e-77 254.61 In-house 1-265 (265) Show / Hide 
Range on Protein: 650-903
Range on HMM: 1-265/265
Sequence Identity: 40% (108 aa)

FEFKEKLGQGGYGAVFKVLHRETNFPLAIKVLSITPTRIKDIEKEIDLLKK-CRCPNVLSYYGSI-----SSKLTELWILMDHCAVGSINDMMKIC-CDT
||  | .|.| || |.| .|  |    ||||....     .| .||..|||     |. .|||       . .   ||. |. |. ||. |..|    ..
FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVREDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGHDHQLWMVMEFCGAGSVTDLVKMTKGQS

LDEEQIAVVTLNVLNGLGYLHSKGIVHLDVKAANILLTEDKQIKIADFGVSQQLQTEYGQANVYIGSPLYMAPEVIL-----KAPYNSKADIWSLGITLI
| |. || .. ..| || .||.. ..| |.|  |.|||.. ..|. ||||| ||.   |  | .|| | .||||||      .| | ...|.||.||| |
LKEDWIAYICREILRGLAHLHQHKVIHRDIKGQNVLLTHNAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSVGITAI

ELAEGRPPNRGLRSMNQLVEIPNMPPPKLSNPKDWSPCFNNFLATCLVKDPVQRPSVIDLLSHDFI
|.|||.||   .. |  |. ||  |||||   | ||  |.||. .||.|.  |||.  ..| | ||
EMAEGQPPLCDMHPMRALFLIPRNPPPKLK-SKKWSKKFHNFMEKCLIKNYHQRPYTEQMLKHPFI
Kinase PakE.AA SLK 650-903 37 7.8e-73 245.02 In-house 1-259 (259) Show / Hide 
Range on Protein: 650-903
Range on HMM: 1-259/259
Sequence Identity: 37% (97 aa)

FEFKEKLGQGGYGAVFKVLHRETNFPLAIKVLSITPT-RIKDIEKEIDLLKKCRCPNVLSYYGSISSKLTELWILMDHCAVGSINDMMKICCDTLDEEQI
.|    || | .| | |  |.|..   | |.. |     ..|   |||.| .|  ||..  |.. .    .||.....|. | .. .|     .| |.||
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKDEEELEDYMVEIDILSECKHPNIVKLYEAYYYD-NKLWMMIEFCDGGAVDNIMVELEHPLTEDQI

AVVTLNVLNGLGYLHSKGIVHLDVKAANILLTEDKQIKIADFGVSQQLQTEYGQANVYIGSPLYMAPEVIL-----KAPYNSKADIWSLGITLIELAEGR
..|   ....| .|||. ..| |.|| |||.| | ....|||||| ... .  .   .|| | .|||||..      .||  |||||||||||||.|.. 
QYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMAQME

PPNRGLRSMNQLVEIPNMPPPKLSNPKDWSPCFNNFLATCLVKDPVQRPSVIDLLSHDFI
||.  .  |  |. |    ||.| .|  ||  |..||  |||||| .|..  .|. | ..
PPHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase PakE.AA KHS 650-903 40 9.9e-73 243.93 In-house 1-258 (258) Show / Hide 
Range on Protein: 650-903
Range on HMM: 1-258/258
Sequence Identity: 40% (106 aa)

FEFKEKLGQGGYGAVFKVLHRETNFPLAIKVLSITPT-RIKDIEKEIDLLKKCRCPNVLSYYGSISSKLTELWILMDHCAVGSINDMMKICCDTLDEEQI
.|   ..| | || |.|  . ...   |.||. . |   .. | .|| ..|.|| ||...|.||   .   ||| |..|  ||. |. ..    | | ||
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDFAVIQQEIMMMKDCRHPNIVAYFGSY-LRRDKLWICMEYCGGGSLQDIYHVTG-PLSELQI

AVVTLNVLNGLGYLHSKGIVHLDVKAANILLTEDKQIKIADFGVSQQLQTEYGQANVYIGSPLYMAPEVI---LKAPYNSKADIWSLGITLIELAEGRPP
| |. ..|.|| ||||.| .| |.| ||||||.. ..|.|||||| |.    ..   .|| | .|||||     |  ||   |||..||| |||||  ||
AYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAELQPP

NRGLRSMNQLVEIP--NMPPPKLSNPKDWSPCFNNFLATCLVKDPVQRPSVIDLLSHDFI
   |  |  |  .   |  |||| . . ||. | .|. ..|.|.| .||.   ||.| |.
MFDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase PakE.AA Pkinase 650-903 26 3e-72 251.13 Pfam 1-293 (293) Show / Hide 
Range on Protein: 650-903
Range on HMM: 1-293/293
Sequence Identity: 26% (79 aa)

FEFKEKLGQGGYGAVFKVLHRETNFPLAIKVLSITPTRIKDIEK-----EIDLLKKCRCPNVLSYYGSISSKLTELWILMDHCAVG----SINDMMK-IC
.....|.|.|..| |.|  |. |.   |.|...   .. .  .      || ..|....||.. .|..  .  ..... |..|  |    .  |...   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWR

CDTL--DEEQIAVVTLNVLNGLGYLHSKGIVHLDVKAANILLTEDKQI----KIADFGVSQQL-QTEYGQANVYIGSPLYMAPEVIL-KAPYNSKADIWS
  ..  .|...  . . .| || |.||.||.| |.| .|||. .. .|    ||.|||.. |.    .. .... |.| |||||||.   .| .|.|.||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGITLIELAEGRPPNRGL----RSMNQLVEIPNMPPPKLSNPKDWS---------------------PCFNNFLATCLVKDPVQRPSVIDLLSHDFI
.|..|.|.. |||| .|     . ..|.. | .  .|.|. . .|.                     . .  |.  || ||| .||.  ..| |...
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase PakE.AA Ste20-DD1 693-903 44 2.2e-68 233.48 In-house 54-268 (268) Show / Hide 
Range on Protein: 693-903
Range on HMM: 54-268/268
Sequence Identity: 44% (97 aa)

KEIDLLKKC-RCPNVLSYYGSISSKLTELWILMDHCAVGSINDMMKICCDTLDEEQIAVVTLNVLNGLGYLHSKGIVHLDVKAANILLTEDKQIKIADFG
|||| ||   .|| .  | |    |   | | |  |  ||| | |..|  .| ||||| .   .  || ||||. |.| |.|| |.|. .  | | ||||
KEIDILKNTMDCPYIVKYHGCY-IKENMLMIVMEYCDGGSILDIMQMCSKRLIEEQIAAICYQIVKGLVYLHSNRITHRDIKAGNVLVNKEGQPKLADFG

VSQQLQ-TEYGQANVYIGSPLYMAPEVILK----APYNSKADIWSLGITLIELAEGRPPNRGLRSMNQLVEIPNMPPPKLSNPKDWSPCFNNFLATCLVK
||  .  . . .  | ||||  |.||.|        | .|||||||||| ||.||  ||   .        ||  .|| |  | .||| || |   || .
VSTIAVNQGFKMNTV-IGSPYWMSPEIIMPPKGSQGYDQKADIWSLGITAIEMAESKPPRFNVNPVRVIFVIPHQQPPTLKIPSNWSPEFNDFIKQCLNM

DPVQRPSVIDLLSHDFI
.|  |||  .||.| ||
NPDKRPSAQQLLNHPFI
Kinase PakE.AA PAKA 650-845 40 1.4e-53 184.29 In-house 1-202 (260) Show / Hide 
Range on Protein: 650-845
Range on HMM: 1-202/260
Sequence Identity: 40% (82 aa)

FEFKEKLGQGGYGAVFKVLHRETNFP--LAIKVLSITPTRIK-DIEKEIDLLKKCRCPNVLSYYGSISSKLTELWILMDHCAVGSINDMMKICCD----T
..| ||.|||. |.|...  ..||     |||.. .     |  |  || ..|.|. .|.  |. |      |||. |.  . |.  |  . ||.    .
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVMKECKHKNIVNYIDSYLV-DDELWVVMEYMEGGCLTDVITQCCNIQCNY

LDEEQIAVVTLNVLNGLGYLHSKGIVHLDVKAANILLTEDKQIKIADFGVSQQLQTEYGQANVYIGSPLYMAPEVILKAPYNSKADIWSLGITLIELAEG
.||.||| |   .| || ..|||...| |.|  ||||  | ..||.|||   ||. |  . |   | | .||||||..  |. | ||||||| .||..||
MDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIEMIEG

RPP
 ||
EPP
Kinase PakE.AA Pkinase_Tyr 650-845 26 2.6e-28 96.49 Pfam 1-214 (270) Show / Hide 
Range on Protein: 650-845
Range on HMM: 1-214/270
Sequence Identity: 26% (58 aa)

FEFKEKLGQGGYGAVFKVLHR----ETNFPLAIKVL--SITPTR--IKDIEKEIDLLKKC-RCPNVLSYYGSIS-SKLT-ELWILMDHCAVGSINDMMKI
 .| .|||.| .| |.|   .    .|. | |.|.|  . ..    ..|  .|. ..|.  ..||....|| ..  .   ...| | ... |.  |  . 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

C---CDTLDEEQIAVVTLNVLNGLGYLHSKGIVHLDVKAANILLTEDKQIKIADFGVSQQL-QTEYGQANVYIGSPL---YMAPEVILKAPYNSKADIWS
     . |. ...    . . .|. ||.||...| |. | |.|.||....||.||| .  .  ..|    .  |..|    ||||.|    ...| |.||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

LGITLIELAE-GRPP
 |... |.   |. |
FGVLMWEIFTYGEQP
Kinase PakE.AA TyrKc 650-903 24 6e-20 73.52 SMART 1-280 (280) Show / Hide 
Range on Protein: 650-903
Range on HMM: 1-280/280
Sequence Identity: 24% (70 aa)

FEFKEKLGQGGYGAVFKVLHRETNFPLAIKVLSITPTRIKDIEKEIDLLKKC--RCPNVLSYYGSISSKL------TELWILMDHCAVGSINDMMKICCD
 ....||| | .| |.|   .    . |.|.|      ..|. .|. ...|   . ||..  || ....         |.|.| ... |. .|  . . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

TLDEEQIAVVTLNVLNGLGYLHSKGIVHLDVKAANILLTEDKQIKIADFGVSQQLQTE--YGQANVYI------GSP--L---YMAPEVILKAPYNSKAD
.|  ..     . . .|  |||||...| |  | |.|..|....||.||| |  .  .   | .  |.      |.   |    ||||.| .  ...| |
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSD

IWSLGITLIELAE-GRPPNRGL----RSMNQLVEIPN----MPPPKL-----SNPKDWSPCFNNFLATCLVKDPVQRPSVIDLLSHDFI
.|| |... |.   | .|  |      |  ...|       ||.|.      . .   .  ..    .|   || .||.  ..  |...
VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF-VCCPDEMYQ-IMKQCWHEDPEDRPTFSEI--HECF
Kinase PakE.AA PAKA 864-903 40 4.5e-14 45.89 In-house 221-260 (260) Show / Hide 
Range on Protein: 864-903
Range on HMM: 221-260/260
Sequence Identity: 40% (16 aa)

PKLSNPKDWSPCFNNFLATCLVKDPVQRPSVIDLLSHDFI
|.. .|  ||. |..||..|| .|. .|.|. .||.| |.
PDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL