DDB0229851

Species: Slime mold
Alias: DdisK218, DDB0229851
External Links: DictyBase Link ,
Annotation:

Classification

Group: TKL
Family: LISK
Subfamily: LISK-DD1

Sequence

Name Sequence Type Origin Length Description Download
DDB0229851.AA Protein None 921 None Fasta, JSON
DDB0229851.kin_dom Protein Kinase Domain None 239 None Fasta, JSON

Protein domain

Protein domains of DDB0229851.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0229851.AA LISK-DD1 28-274 46 6.30000000001e-169 567.5 In-house 1-290 (290) Show / Hide
Range on Protein: 28-274
Range on HMM: 1-290/290
Sequence Identity: 46% (136 aa)

IIGSGGFGKVYQGVLNGKEIGIKKITISDNDPNRDILLKFLEREIYTLKM---LSHPNVIKFYGIAEK-------------ERSLFLLTELVSGGDLHWY
.||.|.|||||.|...|....||||....||||.....||..|||..||.   ..|||...|.||.|.             |.||...||...|||||||
EIGKGSFGKVYKGCYFGTPVAIKKIHKQPNDPNDPDYWKFMQREIKMLKNLLNIRHPNIVQFIGICEHPLASPSLVNRLLNESSLYIVTEFIEGGDLHWY

IKN------------KSIDITWKLKVKIARDIAASMAYLHENGVIHRDLKSTNLLVAEN----WVIKVCDMGLARKMDKS----EKSKMTICGTDDWMAP
.||            ..|.|.|||.||||.|||..|||||....|||||||.|.||.||    |.|||||.|.||.....    ....|||||||.||||
LKNTPFDDTPEQYIHHKIPIPWKLRVKIALDIACAMAYLHSKNIIHRDLKSKNILVDENGDSQWRIKVCDFGFARMFEQKKNQQNNRHMTICGTDNWMAP

EVLIGEEYDASCDVFSFGMVLIELITRENLTPRIRNE----DLGVDQKFFLS-KVPAD--CPKELLRLVSECCKVAPSGRPSASNILGLL
||..|..||.|||||||||||.|||||.....|....    ....||..|.. |.|.|  ||.|...|...|||..|..||| . |.  |
EVILGMSYDWSCDVFSFGMVLLELITRKKPDKRMWQRSPMNCFDIDQEEFRQQKIPKDNDCPREFMDLCMWCCKYDPNNRPSFKEIVQTL

Kinase DDB0229851.AA LISK 28-274 42 1.4e-156 512.45 In-house 1-296 (296) Show / Hide
Range on Protein: 28-274
Range on HMM: 1-296/296
Sequence Identity: 42% (125 aa)

IIGSGGFGKVYQGVLN--GKEIGIKKITISDNDPNRDILLKFLEREIYTLKMLSHPNVIKFYGIAEK-ERSLFLLTELVSGGDLHWYIKN---KSIDITW
.||.|.|||||.| ..  |... ||.|....||||.. ..||..||....|.|.|||...|.|. .. ...|...||...|||||.|.|.   ..|...|
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPW

KLKVKIARDIAASMAYLHENGVIHRDLKSTNLLVAEN----WVIKVCDMGLARKMDKSE----------------------------------KSKMTIC
...||||.||| .|.|||....|||||||.|.|| ||    | |||||.|.||.||...                                  |..||||
PQRVKIALDIACGMSYLHSMNIIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRRMTIC

GTDDWMAPEVLIGEEYDASCDVFSFGMVLIELITRENLTP--RIRNE--DLGVDQKFFLSKVPAD-CPKELLRLVSECCKVAPSGRPSASNILGLL
||..|||||.|.|..|| ||||||||.||.|.|||....|  ..|..  |.|.|...|..|.. | ||...|.|. .|||. |. ||| . |.  |
GTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRVKADPDYWPRTPQHDFGLDYEEFWQKICPDDCPPPFLDLCFDCCKYDPKNRPSFKEIVQWL

Kinase DDB0229851.AA TKL 29-274 27 3.1e-88 299.44 In-house 1-364 (364) Show / Hide
Range on Protein: 29-274
Range on HMM: 1-364/364
Sequence Identity: 27% (102 aa)

IGSGGFGKVYQGVLNG----------KEIGIKKITISDNDP-------------------NRDILLKFLEREIYTLKMLS---HPNVIKFYGIAEKERS-
|||||||.||.|...|          |.. .||. . ..|                    | . . .| ..|.. ..|.|   |||...|.|..  ... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------LFLLTELVSGGD-LHWYIKNKSIDITWKLKVKIARDIAASMAYLHENG--------VIHRDLKSTNLLVAENWV--------------
            |.. .|...||. || ..        | .....|.|||  |.||| ..        .||||||| |.|| |||               
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

IKVCDMGLARKMDKSEK-------------------SKMTICGTDDWMAPEVLIGE----------------EYDASCDVFSFGMVLIELITRENLTPRI
.|.||.||.| |..|..                    .||.|||  ||||||| |.                ||. .|||.|||.|| |..||.     .
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY

RNED-----------LGVDQKFFLSKVP------------ADCPKELLRLVSECCKVAPSGRPSASNILGLL
 ...            .| .|.    .|             |||... .|  .|..  |. |||.. ||  |
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase DDB0229851.AA Pkinase 23-274 26 2.4e-66 231.5 Pfam 1-293 (293) Show / Hide
Range on Protein: 23-274
Range on HMM: 1-293/293
Sequence Identity: 26% (79 aa)

FDPLSIIGSGGFGKVYQGVLNGKE--IGIKKITISDNDPNRDILLKFLEREIYTLKMLSHPNVIKFYGIAEKERSLFLLTELVSGG----DLHWYIK-NK
.  ...||||.||.||...  | .    .|.|  ...... |. .  | .||. .|.|.|||....|.. | .... . .|.. ||    ||. ||.  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

SIDI--TWKLKVKIARDIAASMAYLHENGVIHRDLKSTNLLVAENWVI----KVCDMGLARKM-DKSEKSKMTICGTDDWMAPEVLI-GEEYDASCDVFS
.  .  ...   .... |.  ..|.|..|.||||||. |.|. .| .|    |.|| |||...   .    .|.||| ..|||||.  |..|. ..|..|
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

FGMVLIELITRENLTP-RIRNEDLGVDQKFFLSKVPA-----DCP-----------------------KELLRLVSECCKVAPSGRPSASNILGL--L
.| .|.|..... . | .. ..|  .||.. . ..       |.|                       .|.. ... |... |. ||.|  ||    .
CGCILYEMLCGRPPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase DDB0229851.AA Dicty4 23-276 33 1.7e-61 203.94 In-house 1-277 (277) Show / Hide
Range on Protein: 23-276
Range on HMM: 1-277/277
Sequence Identity: 33% (93 aa)

FDPLSIIGSGGFGKVYQGVLNGKEIGIKKITISDNDPNRDILLKFLEREIYTLKMLSHPNVIKFYGIAE----KERSLFLLTELVSGGDLHWYIKN----
 .  ..||.|.||.|| |   |||  .||   ..|.  .  .|. . .|.  .. ..|||...|.|       .  ..   ||... |.|.  . .    
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLN-NHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSE

--KSIDITWKLKVK---IARDIAASMAYLHE-N-GVIHRDLKSTNLLVAENWVIKVCDMGLAR--KMDKSEKS-KMTICGTDDWMAPEVLIGEEYDASCD
  .|| . | |  .   .|.|.|  |..||. |  .||||||| |||| .||..|||| ||..  | ... |   || |||  ||||||. ...|. . |
QQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKAD

VFSFGMVLIELITRENLTP-RIRNED---LGVDQKFFLSKVPADCPKELLRLVSECCKVAPSGRPSASNILGL--LEY
|.|||.|| |. ||. . .  ... .    .|..|    ..|..||. . .|. .|    |. ||| . |.    || 
VYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH

Kinase DDB0229851.AA TKL-Unique 25-219 33 4.2e-60 205.99 In-house 1-225 (290) Show / Hide
Range on Protein: 25-219
Range on HMM: 1-225/290
Sequence Identity: 33% (76 aa)

PLSIIGSGGFGKVYQGVLNGKEIGIKKITISDNDPNRDILLKFLEREIYTLKMLS-HPNVIKFYGIAE----KERSLFLLTELVSGGDLHWYIK------
... ||.||.|.||.|. .|... ||.. .  .|.. ... .| |.|. ..|.|  |||. ...|.      ..  ... .| ..|| |. ..       
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHP-NEDSSNEMMQEF-ENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

---NKSIDITWKLKVKIARDIAASMAYLHENG--VIHRDLKSTNLLVAEN-----WVIKVCDMGLARKMDKSEKSKMT-I--------CGTDDWMAPEVL
   |..........||.|.|||  | ||| ..  .|||||||.|.|| .|     | ||.|| ||..  .|. |.. . .        ||.  |||||||
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

IG--EEYDASCDVFSFGMVLIELITRE
 .  . |. ..||.|||.||.|..||.
RMNFCQYSEKSDVYSFGIVLWEIATRK

Kinase DDB0229851.AA MLK 23-219 29 1.3e-58 201.03 In-house 1-233 (291) Show / Hide
Range on Protein: 23-219
Range on HMM: 1-233/291
Sequence Identity: 29% (71 aa)

FDPLSIIGSGGFGKVYQGVLNGKE-----IGIKKITISDNDPNRDILL-----KFLEREIYTLKMLSHPN----VIKFYGIAEKERS-LFLLTELVSGGD
.. . .||||.||||. |.  .|.     . .|....   ..  |.       . .|.|.. |..|||||    .|.|||.  .. . .....| ..|| 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRA---RIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGS

LHWYIKNKS-------------IDITWKLKVKIARDIAASMAYLHENG---VIHRDLKSTNLLVAE------NWVIKVCDMGLARKMDKSEKS-KMTICG
|. ......             . ..  .....| ..|  |.|||..    .||||||| |.|..|      . . |.|| |..|.. ... . .|  .|
LYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAG

TDDWMAPEVL---IGEEYDASCDVFSFGMVLIELITRE
|  ||||||.    .| |. .|||.|.|.|| |..|||
TYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE

Kinase DDB0229851.AA S_TKc 23-277 29 9.2e-58 199.13 SMART 1-231 (231) Show / Hide
Range on Protein: 23-277
Range on HMM: 1-231/231
Sequence Identity: 29% (79 aa)

FDPLSIIGSGGFGKVYQGVLNG--KEIGIKKITISDNDPNRDILLKFLEREIYTLKMLSHPNVIKFYGIAEKERSLFLLTELVSG--GDLHWYIKNKSID
.. | .||.|.|||||... ..  ..  ||.|             . ..|||  ||.  |||..|.|.. .   .|.. .|...|  |||..|||..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----ITWKLKVKIARDIAASMAYLHENGVIHRDLKSTNLLVAENWVIKVCDMGLARKMDKSEKSKMTICGTDDWMAPEVLIGEEYDA-SCDVFSFGMVL
     ..     .... |.  ..|.|..|.||||||  |.|. |  .||.|| ||||..       .|.||| ..||||||    |.  .||. |.| .|
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

IELITRENLTPRIRNEDLGVDQKFFLSKVPADCPKELLRLVSECCKVAPSGRPSASNILG------LLEYI
.|..... . |          | . . |.    ..|.. ... |... |. ||.|  .|       . ...
YEMLCGYPPFP----------QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase DDB0229851.AA STE 23-271 20 3.5e-49 169.72 In-house 1-352 (359) Show / Hide
Range on Protein: 23-271
Range on HMM: 1-352/359
Sequence Identity: 20% (75 aa)

FDPLSIIGSGGFGKVYQGVLN-----------------GKEIGIKKITISDNDP---------NRDI---LLKFLEREIYTLKMLS--HPNVIKFYGIAE
.. ...||.|.||.||... .                 |. . ||.. ......         ....    .. ...|| ..| ..  |||..|.||  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KER-------SLFLLTELVSGGDLHWYIKNK-SIDIT------------WKLKVKIARDIAAS-MAYLHENGVIHRDLKSTNLLVAENWVIKVCDMGLAR
||        .|..  |...|| |   ||.| ..  .             ..  .|.|.|    ..|||....||||.|. | |.     .| || |.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

KMDK---------------SEKSKM-TICGTDDWMAPEVLIGEE------YDASCDVFSFGMVLIELITRENL---------------------------
....               . ..|  |..||  ||||||. ...      ||..||. |.| ..||..| .                             
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

-----TPRIRN--------------EDLGVDQKFFLSKVPADCPKELLRLVSECCKVAPSGRPSASNIL
      |.. .              . .          .|  . .|.   .. |..  |. ||.||  |
IVNGPPPPLPDHLSQNEMISYGGSGT-T----------YPHKWSPEFKDFINKCLQKDPNKRPTASQLL

Kinase DDB0229851.AA TyrKc 23-274 25 9.3e-49 169.22 SMART 1-280 (280) Show / Hide
Range on Protein: 23-274
Range on HMM: 1-280/280
Sequence Identity: 25% (73 aa)

FDPLSIIGSGGFGKVYQGVLNGKEIGIKKITISDNDPNRDILLKFLEREIYTLKML--SHPNVIKFYGIAEKE-------RSLFLLTELVSGGDLHWYIK
   . ..|.| ||.||.|...  .  .|..  .         .. . ||.  ...|  .|||....||.. ..         |....|....|||. |..
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA--------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

NKSIDITWKLKVKIARDIAASMAYLHENGVIHRDLKSTNLLVAENWVIKVCDMGLARKMDKS----EKSKMTIC----GTDD-----WMAPEVLIGEEYD
..  ....| ..... .||. |.|||....|||||   | ||.|| ..|..| ||.|. .      | ...       |...     |||||..   .. 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

ASCDVFSFGMVLIELITR-ENLTPR-----IRNEDL--GVDQKFFLSKVPAD-------CPKELLRLVSECCKVAPSGRPSASNILGLL
   ||.||| .. |. |. .   |      . |...   |.| . . . | |       ||.|. .. ..|..  |. ||. |.|  ..
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Pkinase_Tyr DDB0229851.AA Pkinase_Tyr 21-274 28 3.6e-48 163.76 Pfam 1-270 (270) Show / Hide
Range on Protein: 21-274
Range on HMM: 1-270/270
Sequence Identity: 28% (80 aa)

IKFDPLSIIGSGGFGKVYQGVLN------GKEIGIKKITISDNDP-NRDILLKFLEREIYTLKML-SHPNVIKFYGIAE-KERS--LFLLTELVSGGDLH
|.|.    .|.| ||.||.|...      . .  .|..  .  .. |  .. .|.. |. ..| | .|||....||.   ....  ... .|.. .|||.
ITFG--KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQN--CREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL

WYIKNK---SIDITWKLKVKIARDIAASMAYLHENGVIHRDLKSTNLLVAENWVIKVCDMGLARKM-------DKSEKSKMTICGTDDWMAPEVLIGEEY
 | ...      .| | .......||. |.||.... |||||   | ||.|| |.|.|| |||| .        |....|. |     |||||..   ..
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIK----WMAPECINYGKF

DASCDVFSFGMVLIELITRENLT--PRIRNED--LGV-DQKFFLSKVPADCPKELLRLVSECCKVAPSGRPSASNILGLL
    || ||| .. |..|.      | . ||.    . ..   . . | .||.|. .|  .| .  |. ||. | |.  |
TTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPC-PENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase DDB0229851.AA Dicty5 27-218 36 4.5e-48 163.54 In-house 5-199 (260) Show / Hide
Range on Protein: 27-218
Range on HMM: 5-199/260
Sequence Identity: 36% (74 aa)

SIIGSGGFGKVYQGVLNGKEIGIKKITISDN----DPNRDILLKFLEREIYTLKMLS--HPNVIKFYGIAEKERSL-FLLTELVSGGDLHWYIKNKSI--
 .| ||  |.||.|. .|. . ||    ..|    |      .   .||.  . .    |||.|..||   ..    | .||... | |  | . .    
DWIASGASGRVYNGIYKGMDVAIKVYS-QENCMCFD------WNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTT

--DITWKLKVKIARDIAASMAYLHENGVIHRDLKSTNLLVAENWVIKVCDMGLARKMDKSEKSKMTI-CGTDDWMAPEVLIGEEYDASCDVFSFGMVLIE
   | . ... .| ||| || .||  ..||||||| | |. ||| ||. | |  |  |   . .||.  ||  |||.|.  |  |.  |||.||| || |
GQPIAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVD--NRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWE

LITR
..||
MFTR

Kinase DDB0229851.AA LRRK 21-219 27 5.2e-45 155.85 In-house 1-279 (351) Show / Hide
Range on Protein: 21-219
Range on HMM: 1-279/351
Sequence Identity: 27% (77 aa)

IKFDPLSIIGSGGFG-KVYQGVLNG----------------------------KEIGIKKITI----SDNDPNR------------------------DI
.|. ..  ||.|||| .||.. ..|                            ... |||...    .||| .                         | 
LKIEEQ--IGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDND-CNNSNNNNNLNNNNSEQVEDMDQNHEDC

LLKFLE--REIYTLKMLSHPNVIKFYGIAEKERSLFLLTELVSGGDLHWYIKNKS--------IDITWKLKVKIARDIAASMAYLHENG--VIHRDLKST
. .| |  .|.. .  | |||... .|.    . | . .|... |||. ...||.        ..|.| || ||| .||  |.||| .   .||||||| 
CRAFREFRHEVWIMSHLNHPNIVSLKGFC--IHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSP

NLLV---A---------ENWVIKVCDMGLARKMDKSEKS--KMTICGTDDWMAPEVLIGE---EYDASCDVFSFGMVLIELITRE
| |.             .. ..|..| |. | | .. ..   ..  |.  |||||.. ..   ||.   |..||||.| ||.||.
NILLWSSPQNHSPNYPNAHVCAKIADFGISR-MFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQ

Kinase DDB0229851.AA TESK 175-276 45 4.7e-31 94.97 In-house 189-292 (292) Show / Hide
Range on Protein: 175-276
Range on HMM: 189-292/292
Sequence Identity: 45% (47 aa)

SEKSKMTICGTDDWMAPEVLIGEEYDASCDVFSFGMVLIELITRENLTPRI--RNEDLGVDQKFFLSKVPADCPKELLRLVSECCKVAPSGRPSASNILG
|.|.|| . |.  ||||||| ||.||   |||||| || |.| | .  |    | |. | | . |  ..| |||.. |.|  .||   |. ||.  .|  
SRKEKMAVVGSPYWMAPEVLRGEWYDEKADVFSFGIVLCEIIARIQADPDYMPRTEKFGLDYQAFKEMCPMDCPEPFLQLAFHCCNMDPKDRPVFHEITK

LLEY
 ||.
HLEW

Kinase DDB0229851.AA TESK 70-170 40 1.9e-25 76.95 In-house 42-146 (292) Show / Hide
Range on Protein: 70-170
Range on HMM: 42-146/292
Sequence Identity: 40% (42 aa)

REIYTLKMLSHPNVIKFYGIAEKERSLFLLTELVSGGDLHWYIKNKSIDITWKLKVKIARDIAASMAYLHENGVIHRDLKSTNLLVA--ENWVIK--VCD
||.  .  |.|||...| |.  ..  |  ||| ..|| |     ....   |. |.. | |||  | |||. || |||| | | ||   .| . .  | |
REVQLMNKLQHPNILRFMGVCVHQGQLHALTEYINGGCLEQLLADSELHLSWTQKIHLAYDIARGMSYLHSKGVFHRDLTSKNCLVRQRDNNQYEAVVGD

MGLAR
 ||||
FGLAR

Kinase DDB0229851.AA TKL-Unique 240-274 40 4e-06 17.97 In-house 256-290 (290) Show / Hide
Range on Protein: 240-274
Range on HMM: 256-290/290
Sequence Identity: 40% (14 aa)

KVPADCPKELLRLVSECCKVAPSGRPSASNILGLL
..| .||||.  |  .|..  || ||| ..|.  |
PIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL

Kinase DDB0229851.AA MLK 241-274 32 8.8e-05 12.66 In-house 258-291 (291) Show / Hide
Range on Protein: 241-274
Range on HMM: 258-291/291
Sequence Identity: 32% (11 aa)

VPADCPKELLRLVSECCKVAPSGRPSASNILGLL
.| .||. . .| ..| .  |. ||| . |.  |
IPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL

Kinase DDB0229851.AA Dicty5 241-278 36 0.000153 11.54 In-house 223-260 (260) Show / Hide
Range on Protein: 241-278
Range on HMM: 223-260/260
Sequence Identity: 36% (14 aa)

VPADCPKELLRLVSECCKVAPSGRPSASNILGLLEYIL
.|.||| |   |.  |    |. |||   |.  .| | 
IPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII

Kinase DDB0229851.AA LRRK 240-276 25 0.00127 8.67 In-house 309-351 (351) Show / Hide
Range on Protein: 240-276
Range on HMM: 309-351/351
Sequence Identity: 25% (11 aa)

KVPAD-CPK-----ELLRLVSECCKVAPSGRPSASNILGLLEY
..| . ||      ... |  .| .  |  ||..| |.  |. 
TIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ