Gene DDB0229863 (Slime mold)

DDB0229863

Species: Slime mold
Alias: DdisK221, DDB0229863
External Links: DictyBase Link ,
Annotation:

Classification

Group: TKL
Family: LISK
Subfamily: LISK-DD1

Sequence

Name Sequence Type Origin Length Description Download
DDB0229863.AA Protein None 597 None Fasta, JSON
DDB0229863.kin_dom Protein Kinase Domain None 246 None Fasta, JSON

Protein domain

Protein domains of DDB0229863.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0229863.AA LISK-DD1 339-581 41 1e-167 563.45 In-house 1-290 (290) Show / Hide 
Range on Protein: 339-581
Range on HMM: 1-290/290
Sequence Identity: 41% (121 aa)

EIGSGKYGSVSLGYWLGTPVAIKKLHE-----NNEETEILVQRELQILKE---IRHPQIVQFLGVSRN------------EKDEIHIITEFMDGGDLFDA
|||.|..|.|..|...||||||||.|.     |........|||...||.   ||||.||||.|....            ......|.|||..||||...
EIGKGSFGKVYKGCYFGTPVAIKKIHKQPNDPNDPDYWKFMQREIKMLKNLLNIRHPNIVQFIGICEHPLASPSLVNRLLNESSLYIVTEFIEGGDLHWY

LIFG------------DIPLTWKEKLRISLDIAQSCRFLHARGILHRDLKSQNILLSTN----RRAKLCDLGLARMFEER----INKRYTCVGTEIWMAP
|...            .||..||....|.||||.....||...|.||||||.|||...|    .|.|.||.|.|||||..    .|...|..||..||||
LKNTPFDDTPEQYIHHKIPIPWKLRVKIALDIACAMAYLHSKNIIHRDLKSKNILVDENGDSQWRIKVCDFGFARMFEQKKNQQNNRHMTICGTDNWMAP

EVCLDQSYSTAVDVFSFGIVLVEIITEKIPDERFPQHR----FQFDAPAFLK-KVPKE--CPPDFSKLCVDCTKYNPKERPSFIKVLDTI
||.|..||....||||||.||.|.||.|.||.|..|..    |..|...|.. |.||.  ||..|..||..|.||.|..||||.....|.
EVILGMSYDWSCDVFSFGMVLLELITRKKPDKRMWQRSPMNCFDIDQEEFRQQKIPKDNDCPREFMDLCMWCCKYDPNNRPSFKEIVQTL
Kinase DDB0229863.AA LISK 339-581 39 7.89999999999e-153 500.04 In-house 1-296 (296) Show / Hide 
Range on Protein: 339-581
Range on HMM: 1-296/296
Sequence Identity: 39% (116 aa)

EIGSGKYGSVSLGYWL--GTPVAIKKLHE-----NNEETEILVQRELQILKEIRHPQIVQFLGVSRNEKDEIHIITEFMDGGDLFDALIFGDI---PLTW
|||.|..|.|  |...  |...|||..|.     |..|..  ..||.|..|..|||.|||| ||........||.||...||||.. | . |    ||.|
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPW

KEKLRISLDIAQSCRFLHARGILHRDLKSQNILLSTN----RRAKLCDLGLARMFEERI----------------------------------NKRYTCV
.....|.||||.....||...|.||||||.|.|...|    .|.|.||.|.|||.....                                  ..|.|..
PQRVKIALDIACGMSYLHSMNIIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRRMTIC

GTEIWMAPEVCLDQSYSTAVDVFSFGIVLVEIITEKIPDE----RFPQHRFQFDAPAFLKKVPKE-CPPDFSKLCVDCTKYNPKERPSFIKVLDTI
||..|||||..|.|||....|||||||||.||||.. .|.    |.|||.|..| ..|..|.... |||.|..||.||.||.||.|||| ......
GTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRVKADPDYWPRTPQHDFGLDYEEFWQKICPDDCPPPFLDLCFDCCKYDPKNRPSFKEIVQWL
Kinase DDB0229863.AA TKL 340-581 25 1e-88 301.04 In-house 1-364 (364) Show / Hide 
Range on Protein: 340-581
Range on HMM: 1-364/364
Sequence Identity: 25% (96 aa)

IGSGKYGSVSLGYWLG----------TPVAIKKLHE------------------------NNEETEILVQRELQILKE---IRHPQIVQFLGVSRNEKD-
|||| .| |  |.| |          ..||.||...                        |..|.. . ..| . ..    .||| ||||.|.. .... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-----------EIHIITEFMDGGDLFDALIFGDIPLTWKEKLRISLDIAQSCRFLHA--------RGILHRDLKSQNILLSTNRR--------------A
           ...|..|...||.|.. |.       |  ..|..||||. . .||.        ..|.||||||.|||.  | .              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KLCDLGLARMFEERIN-------------------KRYTCVGTEIWMAPEVCLDQ----------------SYSTAVDVFSFGIVLVEIITEKIPDERFP
|.||.||.|..... |                   ...|..||  ||||||  .|                .||...||.|||||| ||.| ..| . .|
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

QH----------RFQFDAPAFLKKVP-------------KECPPDFSKLCVDCTKYNPKERPSFIKVLDTI
             |  ..  .|.  .             . |||...||. || ...|..|||| ..|...
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase DDB0229863.AA TKL-Unique 336-581 29 1e-61 211.37 In-house 1-290 (290) Show / Hide 
Range on Protein: 336-581
Range on HMM: 1-290/290
Sequence Identity: 29% (88 aa)

VGNEIGSGKYGSVSLGYWLGTPVAIKKLHENNEETE-ILVQ---RELQILKEIR-HPQIVQFLGVSRN---EKDEIHIITEFMDGGDLFDALI-------
..| ||.|.||.|  | | |.|||||..|. ||. . ...|   .|. ..| .. ||.||.. |..        .  |..|...|| | | |        
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHP-NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--FGDIPLTWKEKLRISLDIAQSCRFLHARG--ILHRDLKSQNILLSTN-----RRAKLCDLGLARMFEERINKRYT---------CVGTEIWMAPEVCL
     ..|... .... .|||| . .|| ..  |.||||||.|.|.. |      ..|.|| ||..    .... ..          .|. .||||||  
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLR

D--QSYSTAVDVFSFGIVLVEIITEKI------PDERFPQHRFQFDAPAFLK-------KVPKECPPDFSKLCVDCTKYNPKERPSFIKVLDTI
.    ||. .||.|||||| ||.| ||      |   .    ..... .  .       ..| .||.....|  .| . .| .||||. ..  .
MNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP---YQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase DDB0229863.AA S_TKc 334-586 26 6e-61 209.72 SMART 1-231 (231) Show / Hide 
Range on Protein: 334-586
Range on HMM: 1-231/231
Sequence Identity: 26% (72 aa)

KFVGNEIGSGKYGSVSLGYWLG--TPVAIKKLHENNEETEILVQRELQILKEIRHPQIVQFLGVSRNEKDEIHIITEFMDG--GDLFDALIFGDIP----
  ....||.| .|.| .... .    ||||...       . ..||.||||. .|| ||....| ..  |......|..||  ||||| .     .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LTWKEKLRISLDIAQSCRFLHARGILHRDLKSQNILLSTNRRAKLCDLGLARMFEERINKRYTCVGTEIWMAPEVCLDQSYST-AVDVFSFGIVLVEII
 ..  .  ..   |..   ..| .||.||||| .||||..  . |.|| |||| .       .|..||  .|||||.   .|.. ..|. |.|..| | .
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

TEKIPDERFPQHRFQFDAPAFLKKVPKECPPDFSKLCVDCTKYNPKERPSFIKVLD----TIQNIYD
. . | .   |.   |.            .|..  .   | ...|..||.  ..|       .  . 
CGYPPFP---QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DDB0229863.AA Pkinase 336-528 32 1e-57 202.83 Pfam 3-211 (293) Show / Hide 
Range on Protein: 336-528
Range on HMM: 3-211/293
Sequence Identity: 32% (69 aa)

VGNEIGSGKYGSVSLGYWLGTP--VAIKKLHENNEETEILVQ----RELQILKEIRHPQIVQFLGVSRNEKDEIHIITEFMDGG----DLFDALI-FGDI
.|  |||| .|.| .... ||.  ||.|..   .|. . ...    .|.||.|...|| ||..... .. ||.|....|...||    |||| .    . 
IGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWRHG

PL--TWKEKLRISLDIAQSCRFLHARGILHRDLKSQNILLSTNRRA----KLCDLGLARMF-EERINKRYTCVGTEIWMAPEVCL-DQSYSTAVDVFSFG
..  ...|  .. . |..   ..|..||.|||||..|||.. |       |.|| |||. | . .    .| .||  .|||||.. .| |...||..|.|
CFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCG

IVLVEIITEKIP
..| | .. . |
CILYEMLCGRPP
Kinase DDB0229863.AA STE 335-573 24 5e-56 192.44 In-house 1-347 (359) Show / Hide 
Range on Protein: 335-573
Range on HMM: 1-347/359
Sequence Identity: 24% (86 aa)

FVG-NEIGSGKYGSVSLGYWL-----------------GTPVAIKKLHENNE-----------------ETEILVQRELQILKEIR--HPQIVQFLGVSR
. |  .||.| .|.| ...                   |. .|||... .|.                 | .  ...|..|.|. .  || ||...|   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

NE------KDEIHIITEFMDGGDLFDALI--FGD-IPLTWK--------EKLR--ISLDIAQS-CRFLHARGILHRDLKSQNILLSTNRRAKLCDLGLAR
.|      .||..|. |.|||| | | .   .|   ||. .        |..   |  .| .    .||  .| |||.|..||||     .|||| |.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

MFEERIN----------------KRYTCVGTEIWMAPEVCL------DQSYSTAVDVFSFGIVLVEIITEKIP--DERFP---------QHRFQ------
 ... .                 ||.|.|||  |||||| .      |. |.| .|. |.|....| .| | |  |.  .         .| .|      
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---FDAPAFLKK---------------VPKECPPDFSKLCVDCTKYNPKERPS
   .. | .  .               .|... |.|      | ...|..||.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPT
Kinase DDB0229863.AA Dicty4 336-528 36 1.1e-49 163.95 In-house 3-216 (277) Show / Hide 
Range on Protein: 336-528
Range on HMM: 3-216/277
Sequence Identity: 36% (78 aa)

VGNEIGSGKYGSVSLGYWLGTPVAIKKLHENNEE--TEILV--QRELQILKEIRHPQIVQFLGVSR---NEKDEIHIITEFMDGGDLFDALIF------G
....||.| .|.| .| | |. ||.|||  .|.    ..|    .|  |.. |||| |..|.| .     .. .. | ||.|  |.|.  |         
IEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQ

DIPLTWKEKLR---ISLDIAQSCRFLHARG--ILHRDLKSQNILLSTNRRAKLCDLGLARMFEERINKRY---TCVGTEIWMAPEVCLDQSYSTAVDVFS
 |.| |   .|   . .|.|.    ||..   |.|||||| |.| . | |.| ||.||.... . ...     | .||  ||||||   |.|  ..||.|
SIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADVYS

FGIVLVEIITEKIP
||||| || | ..|
FGIVLWEILTRQEP
Kinase DDB0229863.AA TK 334-581 15 1.2e-48 160.76 In-house 1-486 (486) Show / Hide 
Range on Protein: 334-581
Range on HMM: 1-486/486
Sequence Identity: 15% (76 aa)

KFVGNEIGSGKYG---SVSLGYWLG---------------------------TPVAIKKLHENNEETEILVQR--------------ELQILKEIR----
  .|...|.| .|    | .| | |                           ||||.| |.| .....   .               |....|  .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPQIVQFLGVSRNEK-----------DEIHIITEFMDGGD----LFDALIFGDIP--------------------------------------------
 || ||...||.  ..             . |..|.|..||    | | |   . .                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LTWKEKLRISLDIAQSCRFLHAR------GILHRDLKSQNILLSTNRR-----------AKLCDLGLA-
                               || ...| ....||. ...||..      .. ||||   |.|.. | .           .|..| ||. 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----RMFEERINKRYTCVGTEI----------------------------WMAPEVCLDQS---------YSTAVDVFSFGIVLVEIIT--EKIPDERF
     .  .   .. |. ....                             |||||. .|.          ..|. ||.|||... || |  .. . .  
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

PQ------HRFQFDAPAFLKK-------------------VPKECP--------------PDFSKLCVDCTKYNPKERPSFIKVLDTI
.       .    .   .|..                    |. ||              ...  |. .| .|.|..||.|  ... .
SNQDVWKDG-DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase DDB0229863.AA TyrKc 334-581 26 1.7e-48 168.38 SMART 1-280 (280) Show / Hide 
Range on Protein: 334-581
Range on HMM: 1-280/280
Sequence Identity: 26% (74 aa)

KFVGNEIGSGKYGSVSLGYWLGTPVAIKKLHENNEETEILVQRELQILKEI--RHPQIVQFLGVSRNEK------DEIHIITEFMDGGDLFDALIFGDIP
   | ..|.| .| | .| |  ..||.|.|.|.    .    ||..|....  .|| ||...|| . ..      . . |..|.|..||| | |      
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

LTWKEKLRISLDIAQSCRFLHARGILHRDLKSQNILLSTNRRAKLCDLGLARMFEER----INKRYTCV----GTE--I---WMAPEVCLDQSYSTAVDV
|..|..| ....||. ...|| ... ||||   |.|.. |...| .| ||.|  ..      .| |  .    |.   .   |||||.  .  ..|. ||
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

FSFGIVLVEIITE-KIPDER-----FPQHRFQFDAPAF--LKKVPK-------ECPPDFSKLCVDCTKYNPKERPSFIKVLDTI
.|||... || |  . | .       .  .   .  .   ... |        .||..  ..  .| ...|..||.|  . . .
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase DDB0229863.AA MLK 334-528 27 9e-48 163.79 In-house 1-235 (291) Show / Hide 
Range on Protein: 334-528
Range on HMM: 1-235/291
Sequence Identity: 27% (65 aa)

KFVGNEIGSGKYGSVSLGYWLGTP-----VAIKKLHENN------EETEILVQRELQILKEIRHPQ----IVQFLGVSRNEKDEIHIITEFMDGGDLFDA
  .   |||| .|.| .|.| ..      ||.|. . .       ..    ...|  .|. ..||     |.||.||. ..  .  |..|...|| |.. 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

L------IF-------GDIPLTWKEKLRISLDIAQSCRFLHARG---ILHRDLKSQNILLS------TNRRAKLCDLGLARMFEERINKRYTC-VGTEIW
|      ..        |.  .   .....|..|.   .||.     | ||||||.|||..       .. .| || |..|.. ..  .  ..  || .|
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYAW

MAPEVC---LDQSYSTAVDVFSFGIVLVEIITEKIP
|||||      . || ..||.|.|.|| |..| ..|
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase DDB0229863.AA LRRK 52-583 12 9e-47 161.71 In-house 80-351 (351) Show / Hide 
Range on Protein: 52-583
Range on HMM: 80-351/351
Sequence Identity: 12% (73 aa)

NSNGKQSTTPKPIAQQQQQQQPPPQQSQQQPPQPLKPIPATRPVPTIPKVQSEDPGPRFGNFTLPTTNSSTKYSTLPSRQFFEVSSSPGDENGTFKRSAA
| |.                                                                                                
NNNN------------------------------------------------------------------------------------------------

PPPPSSLSSNQNGSNLNKVQSPSRPSIPSFEPPTQQPTQPLQKSPRNVPIVPKRTNPSPPSPPLQSPQPTPQQQPPPLKPIPQPQQQQQQQQQQQQQQQQ
                                                                                                    
----------------------------------------------------------------------------------------------------

QQQQQQQQQQQQQQPPPLKPIPQPQQSQPTQPIKSQIQIPITNTNGNTNGHSSLVEKSPRNNESTATTATTKDMWNIDYKELKFVGNEIGSGKYGSVSLG
                                                                                                    
----------------------------------------------------------------------------------------------------

YWLGTPVAIKKLHENNEETEI------------LVQRELQILKEIRHPQIVQFLGVSRNEKDEIHIITEFMDGGDLFDALIF---GD------IPLTWKE
             ... |  .            . ..|. |. . .|| ||. .|.. .    . ...|... ||| . ...    |      . ..|  
-------------SEQVED-MDQNHEDCCRAFREFRHEVWIMSHLNHPNIVSLKGFCIH---PLCMVMEYAPHGDL-YHFLHNKKQDGFHFMKAHISWML

KLRISLDIAQSCRFLHARG--ILHRDLKSQNILL--S----------TNRRAKLCDLGLARMFEERINK--RYTCVGTEIWMAPEVCLDQ---SYSTAVD
||.|.|.||   ..|| .   |.|||||| ||||  |          ..  ||..| |. |||   . .  . .|||...|||||.  .    .|.. ||
KLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVD

VFSFGIVLVEIITEK-IPDERFP-QHRFQFDAPAFLKK---------VPKE-CPP-----DFSKLCVDCTKYNPKERPSFIKVLDTIQN
..|||..| |..| . .| . ..    .|.    ....         .| . |||     ....| ..| . .||.||.|.......  
CYSFGMILWELLTRQHHPFDEHDFFDHMQWM--EQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase DDB0229863.AA DRK 336-528 37 1.5e-45 152.2 In-house 3-201 (258) Show / Hide 
Range on Protein: 336-528
Range on HMM: 3-201/258
Sequence Identity: 37% (75 aa)

VGNEIGSGKYGSVSLGYWLGTPVAIKKLHENNEE-TEIL--VQRELQILKEIRHPQIVQFLGVSRNEKDEIHIITEFMDGGDLFDALIFGDIPLTWKEKL
.|| || | || | .| | || ||.|.|   |..  ..|   .||  ...  ||| |.||.| . |.  .| |..|.|  | |   |    | . |   .
IGNRIGRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMG-TCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMK

RISLDIAQSCRFLHARG--ILHRDLKSQNILLSTNRRAKLCDLGLARMFEERINKRY--TCVGTEIWMAPEVCLDQSYSTAVDVFSFGIVLVEIITEKIP
.. .|.|    .|| .   |.|||||| | |   . . |  | ||.  |     .    | .||  | ||||  .| |    ||.||.||| |..| ..|
QMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECVTRQDP
Kinase DDB0229863.AA Pkinase_Tyr 333-477 33 6.4e-41 139.2 Pfam 1-159 (270) Show / Hide 
Range on Protein: 333-477
Range on HMM: 1-159/270
Sequence Identity: 33% (54 aa)

LKFVGNEIGSGKYGSVSLGYWL------GTPVAIKKLHENNEETE---ILVQRELQILKEI-RHPQIVQFLGVSRNEKDE--IHIITEFMDGGDLFDALI
..|   ..|.| .|.| .|.|       ..|||.|.| |.  . .       ||..|.|.. .|| ||...||   ...   | |..|.| .||| | | 
ITFG-KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

FG---DIPLTWKEKLRISLDIAQSCRFLHARGILHRDLKSQNILLSTNRRAKLCDLGLAR
     . ||| |..| ....||. . .|..... ||||   |.|.. |. .| || ||||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR
Kinase DDB0229863.AA Pkinase_Tyr 495-524 46 3.8e-08 28.21 Pfam 180-209 (270) Show / Hide 
Range on Protein: 495-524
Range on HMM: 180-209/270
Sequence Identity: 46% (14 aa)

WMAPEVCLDQSYSTAVDVFSFGIVLVEIIT
|||||.  .  ..|. || |||... ||.|
WMAPECINYGKFTTKSDVWSFGVLMWEIFT
Kinase DDB0229863.AA DRK 548-583 33 4.3e-07 20.11 In-house 223-258 (258) Show / Hide 
Range on Protein: 548-583
Range on HMM: 223-258/258
Sequence Identity: 33% (12 aa)

VPKECPPDFSKLCVDCTKYNPKERPSFIKVLDTIQN
.|. ||| . .|  ||   .|  |||.  .|  .  
MPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase DDB0229863.AA MLK 548-581 32 3e-06 17.79 In-house 258-291 (291) Show / Hide 
Range on Protein: 548-581
Range on HMM: 258-291/291
Sequence Identity: 32% (11 aa)

VPKECPPDFSKLCVDCTKYNPKERPSFIKVLDTI
.|..||. ..||  .| . .|..||||  ..   
IPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase DDB0229863.AA Dicty4 547-580 33 4.9e-05 12.92 In-house 239-277 (277) Show / Hide 
Range on Protein: 547-580
Range on HMM: 239-277/277
Sequence Identity: 33% (13 aa)

KVPKECPPDFSKLCVDCTKYNPKERPSF---IKV--LDT
..|. ||| ...| ..|   .|. ||||   |.   |..
PIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase DDB0229863.AA Pkinase_Tyr 549-581 30 0.107078 6.37 Pfam 238-270 (270) Show / Hide 
Range on Protein: 549-581
Range on HMM: 238-270/270
Sequence Identity: 30% (10 aa)

PKECPPDFSKLCVDCTKYNPKERPSFIKVLDTI
|. ||..  .|  .| .|.|..||.|  ..  .
PENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase DDB0229863.AA Pkinase 545-581 15 2.505022 2.24 Pfam 256-293 (293) Show / Hide 
Range on Protein: 545-581
Range on HMM: 256-293/293
Sequence Identity: 15% (6 aa)

LKKVPKECPPDFSKLCVDCTKYNPKERPSFIKVLDT--I
.... .. .... ... .| ...||.||..  .|    .
HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF