Gene DDB0229940 (Slime mold)
DDB0229940
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| DDB0229940.AA | Protein | None | 650 | None | Fasta, JSON |
| DDB0229940.kin_dom | Protein Kinase Domain | None | 247 | None | Fasta, JSON |
Protein domains of DDB0229940.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| LIM | DDB0229940.AA | LIM | 5-57 | 26 | 5.8e-13 | 50.31 | SMART | 1-52 (52) | Show / Hide |
Range on Protein: 5-57 Range on HMM: 1-52/52 Sequence Identity: 26% (14 aa) NCGVCKTIVNPGSERVKAGTSVFHAKCFVCKECKNELESFIRSKDGSLICDEC |. |. . . .....|. ..| .||.| .|.. |... .|||.. | | KCARCNKPIYG-DQVMRAMGKHWHPECFCCCHCNKPLGGTFYEKDGKPYCKHC |
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| LIM | DDB0229940.AA | LIM | 6-57 | 28 | 0.000101 | 19.6 | Pfam | 1-55 (60) | Show / Hide |
Range on Protein: 6-57 Range on HMM: 1-55/60 Sequence Identity: 28% (16 aa) CGVCKTIVNPGSERV-KAGTSVFHAKCFVCKECKNELESFI--RSKDG-SLICDEC |. |. . . ..| .| |.| .||.| .|. .|.. . ..|| | | | CAGCNKPIY-DRYYVMRAMNKVWHPECFCCCHCQKPLTPGDECYEHDGNKLYCKHC |
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| LIM | DDB0229940.AA | LIM | 65-115 | 38 | 1.9e-18 | 68.56 | SMART | 1-52 (52) | Show / Hide |
Range on Protein: 65-115 Range on HMM: 1-52/52 Sequence Identity: 38% (20 aa) KCFKCQLPIQS-TIVTARGKSFHNDCFNCASCEKIIKGGFFFVEGEFYCSTC ||..|. ||. ...|.||..| .|| |. |.| . |.|....|..|| | KCARCNKPIYGDQVMRAMGKHWHPECFCCCHCNKPLGGTFYEKDGKPYCKHC |
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| LIM | DDB0229940.AA | LIM | 66-115 | 30 | 3.3e-13 | 49.64 | Pfam | 1-55 (60) | Show / Hide |
Range on Protein: 66-115 Range on HMM: 1-55/60 Sequence Identity: 30% (17 aa) CFKCQLPIQSTIVT--ARGKSFHNDCFNCASCEKIIKGG--FFFVEG-EFYCSTC | .|. ||... .. |..|..| .|| |. | | .. | .....| ..|| | CAGCNKPIYDRYYVMRAMNKVWHPECFCCCHCQKPLTPGDECYEHDGNKLYCKHC |
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| Kinase | DDB0229940.AA | Dicty5 | 386-640 | 62 | 1.4e-210 | 705.84 | In-house | 1-260 (260) | Show / Hide |
Range on Protein: 386-640 Range on HMM: 1-260/260 Sequence Identity: 62% (162 aa) VAFGDVIASGASGKVYKGIYKGRDVAIKVYSSEN-FCFNIEEFDREVTIMSLIDSDHPNFTRFYGANKQNKKYLFHVSELVKSGSLRDLLLDKEK----P |.|.|.|||||||.||.|||||.||||||||.|| .||...||.|||||||...||||||.|.|||...|.||.|||.|....|||...|.|..| | VSFHDWIASGASGRVYNGIYKGMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQP LAYFTQLSIASDIANAMKHLHSIGVIHRDLKSLNVLITEDFTAKVIDFGTSRNVDLAKQMTLNLGTSCYMSPELFKGNGYDETCDVYAFGIVLWEIIARK .|||.||..|.|||..|.||||...|||||||.|.||||....|.|||||||.||....||...||.|.|..|||.|..|...||||.|||||||...|| IAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEMFTRK EPYENINSWSIPVLVAKGERPTIPADCPSEYSKLIKACWTDKPKKRPSFKEICDTLKKIS |||.|||.|.|||.|.||||||||.|||.|.|.|||.||..||..||||||||.....|. EPYDNINNWNIPVMVMKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII |
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| Kinase | DDB0229940.AA | TKL | 392-636 | 27 | 1.6e-97 | 330.27 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 392-636
Range on HMM: 1-364/364
Sequence Identity: 27% (103 aa)
IASGASGKVYKGIYKG----------RDVAIKVYSSEN-FCFNI-----------------------EEFDREVTIMSLIDSDHPNFTRFYGANKQNKK-
| ||..|.||||...| .|||.|...|.| .|.. ..| .|. ||... .||| .|.|. .....
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG
-----------YLFHVSELVKSGSLRDLLLDKEKPLAYFTQLSIASDIANAMKHLHSIG--------VIHRDLKSLNVLITEDFT--------------A
.|. | |... |||...|. ...| ||| .| .||| . .||||||| |.|. |..| .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC
KVIDFGTSRNVDLAKQMTLN--------------------LGTSCYMSPELFKGN----------------GYDETCDVYAFGIVLWEIIARKEPYENIN
|. |||.||... ..|. . || ..|.||...|. |.| ||||.||||||||..|..||....
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP
S----------WSIPVLVAKGERPTIP------------ADCPSEYSKLIKACWTDKPKKRPSFKEICDTL
. . . . . ||.||.|| ||| ...||.. || .|.|||||.|| ..|
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
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| Kinase | DDB0229940.AA | TKL-Unique | 388-636 | 33 | 1.4e-84 | 287.27 | In-house | 1-290 (290) | Show / Hide |
Range on Protein: 388-636
Range on HMM: 1-290/290
Sequence Identity: 33% (97 aa)
FGDVIASGASGKVYKGIYKGRDVAIKVYS-SENFCFN-IEEFDREVTIMSLIDSD-HPNFTRFYGANK----QNKKYLFHVSELVKSGSLRDLLL-----
|. .| .|..|.||||...| .||||. . | . . ..|| .||..|. . . ||| ....|. . ..... . |.| . |||.|.|
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKL--HYHPNIVHYMGYCMDHQVYPPNMCI-VMEYCPGGSLYDVLHQNNNN
----DKEKPLAYFTQLSIASDIANAMKHLHSIG--VIHRDLKSLNVLITED-----FTAKVIDFGTSRNVDLAKQMTLN----------LGTSCYMSPEL
....| . ....| ||| .| .||. . .|||||||.|.|.... . .|..|||.|.. . .||.| .|. .|.||.
NNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEV
FKG--NGYDETCDVYAFGIVLWEIIARKE------PYENINSWSIPVLVAK---GERPTIPADCPSEYSKLIKACWTDKPKKRPSFKEICDTL
... . |.| .|||.||||||||. || ||..... .. .|.. . ||.|| .|| ||..||..||.. | .|||| || |
LRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
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| Kinase | DDB0229940.AA | Dicty4 | 386-638 | 36 | 3.8e-73 | 243.32 | In-house | 1-277 (277) | Show / Hide |
Range on Protein: 386-638 Range on HMM: 1-277/277 Sequence Identity: 36% (101 aa) VAFGDVIASGASGKVYKGIYKGRDVAIKVY--SSENF-CFNIEEFDREVTIMSLIDSDHPNFTRFYGANK---QNKKYLFHVSELVKSGSLRDLLLD--- .... | .|. |.||||. .| .||.|. .|| . ..|| .||.||. | ||| |.|| .. . |.|.. .|.| ||.| INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKI--RHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPS ---KEKPLAYFTQLS---IASDIANAMKHLHS-I-GVIHRDLKSLNVLITEDFTAKVIDFGTSR----NVDLAK-QMTLNLGTSCYMSPELFKGNGYDET ....| . . .. .| |.| | .||. . .||||||| | |. .....|| ||| |. |. ||| || |.|.|| ...|.| EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTA-CGTPCWMAPEVMMHQPYNEK CDVYAFGIVLWEIIARKEPYE--NINSWSIPVLVAK-GERPTIPADCPSEYSKLIKACWTDKPKKRPSFKEICDT--LKK ||| |||||||| |.||| .. . .|. ..|| ||..|| ...||. || |..||||.|| | ADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH |
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| Kinase | DDB0229940.AA | MLK | 386-636 | 33 | 1.4e-70 | 240.78 | In-house | 1-291 (291) | Show / Hide |
Range on Protein: 386-636 Range on HMM: 1-291/291 Sequence Identity: 33% (99 aa) VAFGDVIASGASGKVYKGIYKGRD-----VAIKVYSSENFCFNI-----EEFDREVTIMSLIDSDHPN----FTRFYGANKQNKKYLFHVSELVKSGSLR | .| ||..|||.|| ....| ||.| . .. |. . ..|..|. . . . .||| . .|||. .|. . .. |.| . ||| IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRIL--SHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLY DLLLD-KEKPL----------AYFTQL--SIASDIANAMKHLHSIG---VIHRDLKSLNVLITE------DFTAKVIDFGTSRNVDLAKQ-MTLNLGTSC ..| . . |. | .. ..| ..|..| ||| .||||||| |.||.| . |.|. |||||| . .. |. | || NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYA YMSPELF---KGNGYDETCDVYAFGIVLWEIIARKEPYE-NINSWSIPVLVA-KGERPTIPADCPSEYSKLIKACWTDKPKKRPSFKEICDTL .|.|| . ... |.| |||. .|.||||...|..||. ... | || .|.||.|| .|| .||.| || ..|.|||||..| | WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL |
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| Kinase | DDB0229940.AA | LISK | 391-636 | 31 | 2e-66 | 214.75 | In-house | 1-296 (296) | Show / Hide |
Range on Protein: 391-636 Range on HMM: 1-296/296 Sequence Identity: 31% (96 aa) VIASGASGKVYKGIYK--GRDVAIKVYSSE----NFCFNIEEFDREVTIMSLIDSDHPNFTRFYGANKQNKKYLFHVSELVKSGSLRDLLLDKEK---PL .| .|. |||||| .. |...||| .. | .. ..||| .| .. .||| .|.|. ..|.. |. | |... | |...| |..| || EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNL--RHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPL AYFTQLSIASDIANAMKHLHSIGVIHRDLKSLNVLIT----EDFTAKVIDFGTSRNVDLAK-----------------------------QMTLNL---- . ..|| ||| .| ||| ..||||||| |.|. .....||.||| | .| . .| . PWPQRVKIALDIACGMSYLHSMNIIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRRMT --GTSCYMSPELFKGNGYDETCDVYAFGIVLWEIIARKEPYE------NINSWSIPVLVAKGERPTIPAD-CPSEYSKLIKACWTDKPKKRPSFKEICDT || |.|| .| |||.|||. ||||| |||.|... . . . . . .. .. |. | ||.....| | .||.||||||| .. ICGTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRVKADPDYWPRTPQHDFGLDYEEF---WQKICPDDCPPPFLDLCFDCCKYDPKNRPSFKEIVQW L | L |
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| Kinase | DDB0229940.AA | Dicty4-Unclassified | 386-636 | 34 | 7.1e-65 | 221.12 | In-house | 1-263 (263) | Show / Hide |
Range on Protein: 386-636 Range on HMM: 1-263/263 Sequence Identity: 34% (91 aa) VAFGDVIASGASGKVYKGIYKGRDVAIKVYSSENFCFN---IEEFDREVTIMSLIDSDHPNFTRFYGANKQN---KKYLFHVSELVKSGSLRDLLL---- . | |. ||.||. ||.|||.| . | | |..| .|| |. .| ||| . ||. | . | |. .| | . IQIDQFIGKGHFSKVHKGNWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSI--QHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPS DKEKPLAYFT--QLSIASDIANAMKHLHSIGVIHRDLKSLNVLITEDFTAKVIDFGTSRNVDLAKQMTLNLGTSCYMSPELFKGNGYDETCDVYAFGIVL ....|. . .| ||| | |||. .||||.|| |.|. .| .|. ||| || .| || || ||| .. | ||| ....| EQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMML WEIIARKEPYENIN-SWSIPVLVA-KGERPTIPADCPSEYSKLIKACWTDKPKKRPSFKEICDTL .| . ||| | . .|. |. || || |. ..|||| || . |.|||.. .| . | YELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL |
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| Kinase | DDB0229940.AA | LISK-DD1 | 391-636 | 33 | 3.4e-57 | 196.34 | In-house | 1-290 (290) | Show / Hide |
Range on Protein: 391-636 Range on HMM: 1-290/290 Sequence Identity: 33% (99 aa) VIASGASGKVYKGIYKGRDVAIKVYSSENFCFNIEEF----DREVTIMS-LIDSDHPNFTRFYGANKQ------------NKKYLFHVSELVKSGSLRDL | .|. |||||| | | .||||. .. .| ... .||. . |.. ||| .|.|. . |. |. | |... | |... EIGKGSFGKVYKGCYFGTPVAIKKIHKQPNDPNDPDYWKFMQREIKMLKNLLNIRHPNIVQFIGICEHPLASPSLVNRLLNESSLYIVTEFIEGGDLHWY LLD------------KEKPLAYFTQLSIASDIANAMKHLHSIGVIHRDLKSLNVLITED----FTAKVIDFGTSRNVDLA------KQMTLNLGTSCYMS |.. . .|.. . ..|| ||| || ||| ..||||||| | |. | ..||.||| | .. . || || |. LKNTPFDDTPEQYIHHKIPIPWKLRVKIALDIACAMAYLHSKNIIHRDLKSKNILVDENGDSQWRIKVCDFGFARMFEQKKNQQNNRHMTI-CGTDNWMA PELFKGNGYDETCDVYAFGIVLWEIIARKEPYENINSWS--------IPVLVAKGERP-TIPAD--CPSEYSKLIKACWTDKPKKRPSFKEICDTL ||. | ||. |||. ||.|| |.| || | ... | .... |. ||.| ||.|...| . | .|. ||||||| .|| PEVILGMSYDWSCDVFSFGMVLLELITRKKPDKRMWQRSPMNCFDIDQEEF-----RQQKIPKDNDCPREFMDLCMWCCKYDPNNRPSFKEIVQTL |
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| Kinase | DDB0229940.AA | Pkinase | 386-636 | 24 | 5.3e-56 | 197.17 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 386-636 Range on HMM: 1-293/293 Sequence Identity: 24% (74 aa) VAFGDVIASGASGKVYKGIYKGRD--VAIKV--YSSENFCFNIEEFD-REVTIMSLIDSDHPNFTRFYGANKQNKKYLFHVSELVKSG----SLRDLLL- .| .| ||..|.|||.. || ||.|. ...|. ..... . .|. || .. ||| |.|.. |... | |.. | .| |.. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN--HPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYIST DKEKPL--AYFTQLSIASDIANAMKHLHSIGVIHRDLKSLNVLITEDFTA----KVIDFGTSRN--VDLAKQMTLNLGTSCYMSPELFK-GNGYDETCDV ...... . . ... |. .....|| |.||||||. |.|| .. . |..||| .. || ||. ||.||. . |..|. .|. WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM YAFGIVLWEIIARKEPYENI----NSWSIPVLVAKGERPTIPADCP-----------------------SEYSKLIKACWTDKPKKRPSFKEICDT--L ...|..|.| . .. |. . | . ..... .| .. |.| .| ..|| |.. .|||||....|. . WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | DDB0229940.AA | LRRK | 463-638 | 31 | 2.8e-55 | 189.97 | In-house | 135-351 (351) | Show / Hide |
Range on Protein: 463-638 Range on HMM: 135-351/351 Sequence Identity: 31% (68 aa) ELVKSGSLRDLLLDKEK--------PLAYFTQLSIASDIANAMKHLHSIG--VIHRDLKSLNVLI---T---------EDFTAKVIDFGTSR--NVDLAK |.. |.| ..| .|.. . ..| || .|| .|..||| .||||||| |.|. . .. .||..|||.|| ... . EYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMG -QMTLNLGTSCYMSPELFKGN---GYDETCDVYAFGIVLWEIIARK-EPYENIN-------SWSIPVLVAKGERPTIPAD-CPS-----EYSKLIKACWT ... .|. .|.|| ..| |.| |.|.||..|||.. |. |..... | .. .| ||||| . || .|..||. ||. VAKGC-VGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQ DKPKKRPSFKEICDTLKK .|||||.| .| ..|. HDPKKRPHFSQIVKRLSQ |
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| Kinase | DDB0229940.AA | TyrKc | 386-636 | 29 | 2.5e-53 | 184.39 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 386-636 Range on HMM: 1-280/280 Sequence Identity: 29% (84 aa) VAFGDVIASGASGKVYKGIYKGRDVAIKVYSSENFCFNIEEFDREVTIMSLI--DSDHPNFTRFYGANKQNK------KYLFHVSELVKSGSLRDLLLDK . .|... .|| |.||||..| ..||.|. .. .|.| || ||. . . ||| |.||. | . . |. | |... |.|.| | .. ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA----REDFMREARIMCKLGGH--HPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH EKPLAYFTQLSIASDIANAMKHLHSIGVIHRDLKSLNVLITEDFTAKVIDFGTSRNVDLA-------KQMTLNLGTSCY-------MSPELFKGNGYDET .. | . ||.. .||. | .||| ..||||| |.|..|..|.|. ||| ||... . . . .. |.|| .. . . . RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTK CDVYAFGIVLWEIIAR-KEPYEN-----INSWSIPVLVAKGERPTIPAD--------CPSEYSKLIKACWTDKPKKRPSFKEICDTL ||..||...||| . ..||.. .. . .| .|.|. .|.. ||.| ...| || .|..||.|.||.. . SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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| Kinase | DDB0229940.AA | TAK1 | 386-635 | 29 | 5.8e-52 | 173.78 | In-house | 1-284 (284) | Show / Hide |
Range on Protein: 386-635
Range on HMM: 1-284/284
Sequence Identity: 29% (87 aa)
VAFGDVIASGASGKVYKGIYKGRDVAIKV-----YSSENFCFNIEEFDREVTIMSLIDSDHPNFTRFYG--ANKQNKKYLFHVSELVKSGSLRDLLLD-K
. .. |. | |.| ......|.| |||| . .. ||.. |.. |||| . || | ... .| | | . ||| ..| . |
IQNEHFVGKGTYGVVCKAKWRNKEIAVKRFEFIKYSSEECE--QKNIEREIMQWSRV--DHPNIIKLYGMYACHRQCQCL--VMEYMDCGSLHNFLHGAK
EKPLAYFTQ-LSIASDIANAMKHLHSIG---VIHRDLKSLNVLITEDFTA-KVIDFGTSRNVDLAKQMTLNLGTSCYMSPEL------------------
|. . | . .| . ||| .||||.| .| | .. . |. |||| .|. || | || .| ||
PKWEYTHAHAMSWMHQCAQGVAYLHSMQPKPQIHRDIKPQNMLLCNKHRTLKICDFGTF--CDMHQMMTCNRGTCRWMAPEVRELFDFKSNRIIINQPTG
----FKGNGYDETCDVYAFGIVLWEIIARKEPYENINS----WSIPVLVAKGER-PTIPA--DCPSEYSKLIKACWTDKPKKRPSFKEICDT
|... |.. ||.| .||..||.|.||.||. |.. | ...|.| | . ||| ... |.|| | | |||| .|.
FQKVFRCEKYNMKCDIYSWGIIMWEVISRKHPYDHIMNPNSAYRIMWAIHNGNRPPMETNRSDCPKRIEQFMKCCWDDNPEKRPSMQECVKY
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| Kinase | DDB0229940.AA | S_TKc | 386-643 | 26 | 1.9e-50 | 174.8 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 386-643
Range on HMM: 1-231/231
Sequence Identity: 26% (72 aa)
VAFGDVIASGASGKVYKGIYKG--RDVAIKVYSSENFCFNIEEFDREVTIMSLIDSDHPNFTRFYGANKQNKKYLFHVSELVKS--GSLRDLLLDKEKP-
....| .|| |||||.. |. | ||||. . | . ||. |.. .||| ..|.. ..|. | |.. |.|.|.. .. ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK---HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHG
----LAYFTQLSIASDIANAMKHLHSIGVIHRDLKSLNVLITEDFTAKVIDFGTSRNVDLAKQMTLNLGTSCYMSPELFKGNGYDE-TCDVYAFGIVLWE
. . ... |..|....|| |.|||||| |.|..| . |..||| .| . | || ||.||.. ||. ||....|..|.|
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE
IIARKEPYENINSWSIPVLVAKGERPTIPADCPSEYSKLIKACWTDKPKKRPSFKEICD--TLKKISESL
.... |.. . .. | ..| .|. |.. |.|||. |. . |. . .
MLCGYPPFP-----QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
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| Kinase | DDB0229940.AA | Pkinase_Tyr | 386-636 | 31 | 1.3e-49 | 168.64 | Pfam | 1-270 (270) | Show / Hide |
Range on Protein: 386-636 Range on HMM: 1-270/270 Sequence Identity: 31% (85 aa) VAFGDVIASGASGKVYKGIYK------GRDVAIKVYSSENFCFN---IEEFDREVTIMSLI-DSDHPNFTRFYGANK-QNKK-YLFHVSELVKSGSLRDL . || .. .|| |.||||..| . .||.|. |. .|.| ||. ||. . . ||| |.||. | . ... | |... |.|.| ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGH--HPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY LLDK---EKPLAYFTQLSIASDIANAMKHLHSIGVIHRDLKSLNVLITEDFTAKVIDFGTSRNV---DLA-KQMTLNLGTSCYMSPELFKGNGYDETCDV | .. ..|| . |... .||..| .|.|.. ||||| |.|.||....|. ||| .| . | .. . |.|| .. . . . || LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDV YAFGIVLWEIIA-RKEP-YENINSWSIPVLV-AKGERPTIPADCPSEYSKLIKACWTDKPKKRPSFKEICDTL ..||...|||. ..| |... . .. .|.| .| .|| | .|.| || .|..||.|.|| | WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL |
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| Kinase | DDB0229940.AA | LRRK | 386-435 | 16 | 1.7e-07 | 22.61 | In-house | 1-112 (351) | Show / Hide |
Range on Protein: 386-435 Range on HMM: 1-112/351 Sequence Identity: 16% (18 aa) VAFGDVIASGASG-KVYKGIYKG----------------------------RDVAIKVYSSE---------------------------------NFCFN . .. | .|..| .||.....| .||||.. . ..| . LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA IEEFDREVTIMS || .||.||| FREFRHEVWIMS |
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