Gene DDB0229955 (Slime mold)

DDB0229955

Species: Slime mold
Alias: DDB0229955, DdisK242
External Links: DictyBase Link ,
Annotation:

Classification

Group: TKL
Family: TKL-Unique

Sequence

Name Sequence Type Origin Length Description Download
DDB0229955.AA Protein None 916 None Fasta, JSON
DDB0229955.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of DDB0229955.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0229955.AA TKL-Unique 664-912 45 2e-154 519.31 In-house 1-290 (290) Show / Hide 
Range on Protein: 664-912
Range on HMM: 1-290/290
Sequence Identity: 45% (133 aa)

ISSKLGEGTFGVVYKGLWRGSSVAIKQIKINEDVNNQVLEEFRKELTILSRLR-HPNIVLLMAACT----APPNLCFITEYLPGGSLYDALH--------
...|.|||..|.|||| |||..|||||...|||..|....||..|......|. |||||..|..|.    .|||.|...||.||||||| ||        
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

-SKKIKMNMQLYKKLAIQIAQGMNYLHLSG--VIHRDIKSLNLLLDEH-----MNVKICDFGLSKLKSKSTEMTKS----------IGSPIWMSPELLMG
 ....|.|||.. |.||.|||||.||| ..  .||||.||.|.|.|..     .|.|||||||||..||...||..          .||..||.||.|..
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--EDYTEKVDVYAFGIILWELGTGEL------PYSGLDSVQLALAVTT--KSLRPPIPNAWPYQLSHLIQACWHQDPLKRPSFTEILNLL
  ..|.||.|||.|||.|||. |...      ||.|.|. |.. .|..  ...|||||| .|.....|||.|||.|| .||||.||.. |
NFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase DDB0229955.AA Dicty4 662-914 43 5.6e-122 408.5 In-house 1-277 (277) Show / Hide 
Range on Protein: 662-914
Range on HMM: 1-277/277
Sequence Identity: 43% (121 aa)

LKISSKLGEGTFGVVYKGLWRGSSVAIKQI-KINEDVNNQVLEEFRKELTILSRLRHPNIVLLMAACT----APPNLCFITEYLPGGSLYDALHS-----
..| ...|.| || |||| |||. ||.|     |...    |.||||| .|.. .|||||.|.| |||    .|. .|  |||.| |.||  ||.     
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

-KKIKMNMQLYKK---LAIQIAQGMNYLHL--SGVIHRDIKSLNLLLDEHMNVKICDFGLSK----LKSKSTEMTKSIGSPIWMSPELLMGEDYTEKVDV
 ..||.   |.|.   .|. .|.|||.||   . .||||.|| ||| |....||.||||||.     ..... ..  .|.| ||.|| .|.. |.||.||
QQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADV

YAFGIILWELGTGELPYS--GLDSVQLALAVTTKSLRPPIPNAWPYQLSHLIQACWHQDPLKRPSFTEILNL--LNE
| |||.|||. |.. ||.  . . .|.. ||  | ||||||.  |  ..|||| ||. || .|||| ||..   |..
YSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase DDB0229955.AA TKL 668-912 31 2.4e-114 386.19 In-house 1-364 (364) Show / Hide 
Range on Protein: 668-912
Range on HMM: 1-364/364
Sequence Identity: 31% (118 aa)

LGEGTFGVVYKGLWRG----------SSVAIKQIKI------------------------NEDVNNQVLEEFRKELTILSRLRHPNIVLLMAACTAPPN-
.|.|.||.|||| |||            ||.|..|.                        |.. . .  .....|. ..|||||||||..|..|..||. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------LCFITEYLPGGSLYDALHSKKIKMNMQLYKKLAIQIAQGMNYLHLSG--------VIHRDIKSLNLLLDEHMN--------------V
            ||...|| |||||.. ||       ...  ..|..||.|||||| ..        .||||.|| |.|.||...              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KICDFGLSKLKSKSTEMTKS--------------------IGSPIWMSPELLMGE----------------DYTEKVDVYAFGIILWELGTGELPYSGLD
||||||||. .|.|..|...                    .|.| ||.||.|.|.                .|.||.|||.|||.|||. |...||....
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

SVQLA---------LAVTTKSLRPPIP------------NAWPYQLSHLIQACWHQDPLKRPSFTEILNLL
. .             |  |.||||||            .  | ... |.| ||..|| |||||.|||  |
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase DDB0229955.AA MLK 662-912 35 3.5e-109 369.04 In-house 1-291 (291) Show / Hide 
Range on Protein: 662-912
Range on HMM: 1-291/291
Sequence Identity: 35% (103 aa)

LKISSKLGEGTFGVVYKGLWRGSS-----VAIKQIKINEDVNNQV----LEEFRKELTILSRLRHPN----IVLLMAACTAPPN-LCFITEYLPGGSLYD
.... ..|.|.||.|.|| ||.       ||.|..... .   ..     ..|..|  .|..|.|||    |. ....|. ||. .| ..||..|||||.
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

ALHSKK-------------IKMNMQLYKKLAIQIAQGMNYLHLSG---VIHRDIKSLNLLLDE------HMNVKICDFGLSKLKSKS-TEMTKSIGSPIW
 ||...             . . ...  . | |.|.||.|||      .||||.|| |.|.||      |...||||||.|. .... | |.. .|...|
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAW

MSPELL---MGEDYTEKVDVYAFGIILWELGTGELPYS-GLDSVQLALAVTTKSLRPPIPNAWPYQLSHLIQACWHQDPLKRPSFTEILNLL
|.|| .    .| |.||.||. .|..|||. |.|.||. ..|. . |  |. ..||||||.  |  .. |.. ||.||| ||||| .|.  |
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase DDB0229955.AA DRK 662-914 42 1.5e-101 343.65 In-house 1-258 (258) Show / Hide 
Range on Protein: 662-914
Range on HMM: 1-258/258
Sequence Identity: 42% (111 aa)

LKISSKLGEGTFGVVYKGLWRGSSVAIKQIKINEDVN-NQVLEEFRKELTILSRLRHPNIVLLMAACTAPPNLCFITEYLPGGSLYDALHSKKIKMNMQL
 ||    | | .| |. | |||. ||.|  . |  .|    | ||..| .....||||||.. | .|. ||  | ..||.| ||||  ||  .|.|   |
IKIGNRIGRGNYGEVFRGTWRGTQVAVKMLF-NHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPL

YKKLAIQIAQGMNYLHLSG--VIHRDIKSLNLLLDEHMNVKICDFGLSK----LKSKSTEMTKSIGSPIWMSPELLMGEDYTEKVDVYAFGIILWELGTG
 |.... .| ||.||| .   .|||| || ||| |||  ||. |||||      |.. . ||  .| | | .|| |  . |||| ||| |.|.|||. | 
MKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMT-MCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECVTR

ELPYSGLDSVQLALAVTTKSLRPPIPNAWPYQLSHLIQACWHQDPLKRPSFTEILNLLNE
. || |    |   .|    .|||.|   |     |.. ||  ||  |||. |.|  |  
QDPYFGMPTFQVVFSVGRHGMRPPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase DDB0229955.AA LRRK 662-914 32 1.3e-92 313.97 In-house 1-351 (351) Show / Hide 
Range on Protein: 662-914
Range on HMM: 1-351/351
Sequence Identity: 32% (116 aa)

LKISSKLGEGTFG-VVYKGLWRG----------------------------SSVAIKQIKIN-----EDVNN---------------------------Q
||| ...|.|.|| .||.. |||                            ..||||....       | .|                            
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDND-CNNSNNNNNLNNNNSEQVEDMDQNHEDCCR

VLEEFRKELTILSRLRHPNIVLLMAACTAPPNLCFITEYLPGGSLYDALHSKK--------IKMNMQLYKKLAIQIAQGMNYLHLSG--VIHRDIKSLNL
.. |||.|..|.|.|.||||| |.  |  |  ||...||.| |.||. ||.||        .... .|  |.|.||| ||.||| .   .|||| || | 
AFREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNI

LL---D---------EHMNVKICDFGLSKLKSKSTEMT---KSIGSPIWMSPELLMGE---DYTEKVDVYAFGIILWELGTGE-LPYSGLD-------SV
||   .         .|...||.|||.| .  ... |.   .. | |.||.|| . ..    ||||||.|.||.||||| |.. .|. ..|         
LLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWME

QLALAVTTKSLRPPIPNA-WPY-----QLSHLIQACWHQDPLKRPSFTEILNLLNE
|. .... . |||.||.   |       .. ||| ||..||.|||.|..|.  | .
QIEDKIIEG-LRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase DDB0229955.AA Dicty4-Unclassified 662-912 38 2e-87 296.73 In-house 1-263 (263) Show / Hide 
Range on Protein: 662-912
Range on HMM: 1-263/263
Sequence Identity: 38% (102 aa)

LKISSKLGEGTFGVVYKGLWRGSSVAIKQIKINEDVNN-QVLEEFRKELTILSRLRHPNIVLLMAACTAP----PNLCFITEYLPGGSLYDALH------
..|   .|.| |  |.|| |.|  ||.| .  | .     ....|.||  ||  . ||| | .  .| .|      .| ..| .. | |    |      
IQIDQFIGKGHFSKVHKGNWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQ

SKKIKMNMQLYKKLAIQIAQGMNYLHLSGVIHRDIKSLNLLLDEHMNVKICDFGLSKLKSKSTEMTKSIGSPIWMSPELLMGEDYTEKVDVYAFGIILWE
 . ||..  |  | |. ||||| .||   .||||||| |.|.| | |.|| |||.|   .    ||   | | | ||| ||.| |. | ||| ....|.|
QQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMMLYE

LGTGELPYSGLD-SVQLALAVTTKSLRPPIPNAWPYQLSHLIQACWHQDPLKRPSFTEILNLL
| ||. || .    . .|  |  | ||| ||   .  .. ||  ||| || |||.. .| . |
LATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase DDB0229955.AA Pkinase 662-912 29 2e-84 291.58 Pfam 1-293 (293) Show / Hide 
Range on Protein: 662-912
Range on HMM: 1-293/293
Sequence Identity: 29% (88 aa)

LKISSKLGEGTFGVVYKGLWRGSS--VAIKQIKINEDVNNQVLEEFRK--ELTILSRLRHPNIVLLMAACTAPPNLCFITEYLPGG----SLYDALH-SK
..| .|.|.|.||.|||. ..|..  ||.|.||   . . ..... |.  |. |. ||.||||| |  ... ........||..||    .|.| .. ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

KIKM--NMQLYKKLAIQIAQGMNYLHLSGVIHRDIKSLNLLLDEHMNV----KICDFGLSKL--KSKSTEMTKSIGSPIWMSPELLM-GEDYTEKVDVYA
. ..   ..  |. . ||..|..|.|  |.||||.|. |.|.|.....    |||||||.|.    ... ||   |.| .|.||... |..|. |||...
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

FGIILWELGTGELPYSGL---DSVQLALAVTTKSLRPPIPNAWP-----------------------YQLSHLIQACWHQDPLKRPSFTEILNL--L
.|.||.|. .|..|..|    |.    ...  . ..||..  ||                         . ..|  |...|| |||....||.   .
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase DDB0229955.AA Pkinase_Tyr 662-912 35 1.3e-81 276.98 Pfam 1-270 (270) Show / Hide 
Range on Protein: 662-912
Range on HMM: 1-270/270
Sequence Identity: 35% (98 aa)

LKISSKLGEGTFGVVYKGLWR------GSSVAIKQIKINEDVNNQV--LEEFRKELTILSRL-RHPNIVLLMAACT--APP-NLCFITEYLPGGSLYDAL
...  ||||| ||.|||| |.      .  ||.| .  .|.   .   .|.| .|. |.. | .||||| |...||    | ... ..|| |.|.|.| |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML--KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

HSK---KIKMNMQLYKKLAIQIAQGMNYLHLSGVIHRDIKSLNLLLDEHMNVKICDFGLSKLKSKSTEMT-KSIG---SPI-WMSPELLMGEDYTEKVDV
...   | . .|.   . ..|||.||.||.  . ||||.   | |..| . ||||||||...   ...   .. |    || ||.|| ..   .|.| ||
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDV

YAFGIILWELGT-GELP-YSGLDSVQLALAVTTKSLRPPIPNAWPYQLSHLIQACWHQDPLKRPSFTEILNLL
..||. .||. | || | | |..  ..  ... .  | |.|   |  . .|.. |||.|| .||.|.||.. |
WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase DDB0229955.AA Shk 662-915 41 6.4e-80 271.82 In-house 1-267 (269) Show / Hide 
Range on Protein: 662-915
Range on HMM: 1-267/269
Sequence Identity: 41% (112 aa)

LKISSKLGEGTFGVVYKGLWRGSSVAIKQIKINEDVNNQVLEEFRKELTILSRLRHPNIVLLMAACT-APPNLCFITEYLPGGSLYDALHSKKIKMNMQL
    ..|| | || ||||  ||  ||.|  .    .  . . .||||  | |...||||.| | ||| .|  .  .||  | |.|   ||....|    |
INREDFLGQGSFGKVYKGRCRGKEVAVKVMH-KQNFDENTMTSFRKEVHIMSKIFHPNICLFMGACTSQPGKCMIVTELMPKGNLEKLLHDQMVKKPFIL

YKKLAIQIAQ----GMNYLHL--SGVIHRDIKSLNLLLDEHMNVKICDFGLSKLKSKSTEMTK----SIGSPIWMSPELLMGEDYTEKVDVYAFGIILWE
||  |....     ||| ||   .  ||||.|. ||| |. . ||.||||.|... | ...        |.| || || .|.  | ||.||| |||||||
YKR-AMRMCRDAALGMNWLHGSNCNIIHRDLKTANLLVDQNWRVKVCDFGFSQYMKKHEMLKDKQKGAKGTPLWMAPEVMMNHPYNEKADVYSFGIILWE

LGTGELPYS-GLDSV-QLALAVTTKSLRPPIPNAWPYQLSHLIQACWHQDPLKRPSFTEILNL--LNEI
. | . ||.   ..  ..  |.  | .|||||.  |  | |||| ||  .| .|||| ||.    ||.|
ILTCQEPYPKHHSEYDKFYEAICNKKERPPIPDDCPKSLKHLIQKCWDHNPQRRPSFNEIIQRRILNHI
Kinase DDB0229955.AA CZAK 662-912 39 2e-77 263.55 In-house 1-279 (279) Show / Hide 
Range on Protein: 662-912
Range on HMM: 1-279/279
Sequence Identity: 39% (110 aa)

LKISSKLGEGTFGVVYKGLWRGSSVAIKQIKINEDVNNQV---LEEFRKELTILSRLRHPNIVLLMAACTAPP--NLCFITEYLPGGSLYDAL--HSKKI
||.    |.| || |||. ||| .|||| |  |   |      .. | ||  |.| |.|||.|  . ||..      | ..|.  ||||   |  |.  .
LKFGQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHYFYH

KMNMQLYKKLAIQIAQGMNYLHL----SGVIHRDIKSLNLLLDEHMN-------------VKICDFGLSKL-KSKSTEMTKSIGSPIWMSPELLMGEDYT
| |  |  ..|| ||.||||||       ..|||  | | |||. .               || |||||.. .   .||| ..|.  || ||   || ||
KQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFKGENYT

EKVDVYAFGIILWELGTGELPYSGLDSVQLALAVTTKSLRPPIPNAWPYQLS---HLIQACWHQDPLKRPSFTEILNLL
|||||| ||.|||.. |.. || ..    .|      . |||.|   .        ||  ||   |  |||| .||  |
EKVDVYSFGMILWCIITCDQPYQNMQPMKMAHLAAYENYRPPMPQPMDPMWKNLGELIEMCWNKNPDERPSFKQILQHL
Kinase DDB0229955.AA HH498 662-912 32 7.8e-77 243.04 In-house 1-284 (284) Show / Hide 
Range on Protein: 662-912
Range on HMM: 1-284/284
Sequence Identity: 32% (91 aa)

LKISSKLGEGTFGVVYKGLWRGSSVAIKQIKINEDVNNQV-----LEEFRKELTILSRLRHPN-IVLLMAACTAPPNLCFITEYLPGGSLYDAL------
..   | | | || |||| ||.  ||.|  ...               | .|  |..|| ||. .. . | |  |  .  .|.|  .|||.  |      
IEFHEKIGSGSFGKVYKGEWRNKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILNTIPIG

--------HSKK---IKMNMQLYKKLAIQIAQGMNYLHL---SGVIHRDIKSLNLLLDEHMNVKICDFGLSKLKSKSTE--MTKSIGSPIWMSPELLM-G
        |  |   . |  |    ... .|.||||||      .||||  | | |..|    .. ||| |  .    .  ||| .| . ||.||    .
GAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFSQC

EDYTEKVDVYAFGIILWELGTGELPYSGLDSVQLALAVTTKSLRPPIPNA----WPYQLSHLIQACWHQDPLKRPSFTEILNLL
  |..||||. .....||. |.|.|.. .  .  |  .. .. |||||.      | . | ||| |||. |  ||.| .|. .|
QKYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAEMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL
Kinase DDB0229955.AA S_TKc 662-912 30 1.5e-75 258.22 SMART 1-231 (231) Show / Hide 
Range on Protein: 662-912
Range on HMM: 1-231/231
Sequence Identity: 30% (81 aa)

LKISSKLGEGTFGVVYKGLWRG--SSVAIKQIKINEDVNNQVLEEFRKELTILSRLRHPNIVLLMAACTAPPNLCFITEYLPG--GSLYDALHSKKIK--
 .|  |.|.|.||.|||. ...    ||||.||          | .|.|. ||.. .||||| |  ..    .|....||..|  |.|.| ..... .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---MNMQLYKKLAIQIAQGMNYLHLSGVIHRDIKSLNLLLDEHMNVKICDFGLSKLKSKSTEMTKSIGSPIWMSPELLMGEDYTE-KVDVYAFGIILWEL
   ..    .... ||.....|.|  |.||||.|  |.||||  ..|||||||...       |  .|.| .|.||.|    |.  |.|....|.||.|.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

GTGELPYSGLDSVQLALAVTTKSLRPPIPNAWPYQLSHLIQACWHQDPLKRPSFTEILN---------LL
 .|. |..    .|. . .             . .. ..|. |.. || |||.  |.|.          .
LCGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DDB0229955.AA TyrKc 662-912 33 9.3e-72 245.62 SMART 1-280 (280) Show / Hide 
Range on Protein: 662-912
Range on HMM: 1-280/280
Sequence Identity: 33% (96 aa)

LKISSKLGEGTFGVVYKGLWRGSSVAIKQIKINEDVNNQVLEEFRKELTILSRL--RHPNIVLLMAACTAP-------PNLCFITEYLPGGSLYDALHSK
..   ||||| ||.|||| |.   ||.| .| .       .|.|..|. |...|  .||||| | ..|| .       . |. ..|| |.|.| | |...
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

KIKMNMQLYKKLAIQIAQGMNYLHLSGVIHRDIKSLNLLLDEHMNVKICDFGLSKLKSKS------TEMTKS----IG---SPI-WMSPELLMGEDYTEK
. | .|.   . ..|||.||.|||  ..||||.   | |..|   |||.|||||.           ... ..     |    || ||.|| ..   .|.|
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTK

VDVYAFGIILWELGT-GELPYSG-----LDSVQLALAVTTKSLRPPIPN--------AWPYQLSHLIQACWHQDPLKRPSFTEILNLL
 ||..||. .||. | |. ||.|     ..  ..   | .   .|. ||        . .   . ... ||| || .||.|.||  ..
SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF