Gene DDB0229956 (Slime mold)

DDB0229956

Species: Slime mold
Alias: DdisK243, DDB0229956
External Links: DictyBase Link ,
Annotation:

Classification

Group: TKL
Family: TKL-Unique

Sequence

Name Sequence Type Origin Length Description Download
DDB0229956.AA Protein None 1385 None Fasta, JSON
DDB0229956.kin_dom Protein Kinase Domain None 242 None Fasta, JSON

Protein domain

Protein domains of DDB0229956.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0229956.AA TKL-Unique 760-1005 38 6.5e-134 451.18 In-house 1-290 (290) Show / Hide 
Range on Protein: 760-1005
Range on HMM: 1-290/290
Sequence Identity: 38% (113 aa)

LTKEIGRGVSGVVKRGKWKGYEIAVKQFN-EEELGFSERE-FHSEATIMSVLR-HDNIVHCVGGSA----QPGKMYLVCDYYSRGSLYSVIT--------
  . ||.|..|.|..|||.||..|.|||. .|.. ..... |..| ..|..|. |.||||..|...    .|..|..|..|...||||.|..        
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

-ANICPLSNARIVHLALQVAKGMNYLHSLG--IIHRDLKPGNLLIDQD-----WNIRISDFGLSRVVDNRMTKTVG--------TPC----YMAVEVLKG
 .| |.|.....|..|...|.||.|||...  |||||||. |.|.|..     |||.|.|||||.. ......|..        |.|    .||.|||..
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

L-TDYSQQADVYSFAFVLWECISRQI------PYKDFAQIQWISMVLE--DSFRPPIPDSCLPEFRDLITMCWTSNPDDRPSFQQIITYL
. ..||...|||||..||||...|.|      ||....|.||..|| .  ...|||||..| .|.||||..||...|..||||..||..|
NFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase DDB0229956.AA TKL 764-1005 27 7.4e-101 341.37 In-house 1-364 (364) Show / Hide 
Range on Protein: 764-1005
Range on HMM: 1-364/364
Sequence Identity: 27% (102 aa)

IGRGVSGVVKRGKWKG----------YEIAVKQFNEEELGFSER-------------------------EFHSEAT-IMSVLRHDNIVHCVGGSAQPGK-
||.| .|.| .|||.|          ...|||.|....  ....                         .|  | . .|| |||.|||...| . .|.. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------MYLVCDYYSRGSLYSVITANICPLSNARIVHLALQVAKGMNYLHSLG--------IIHRDLKPGNLLIDQDWN--------------I
            ...| .|...|||.....         .....||..|.||||||| .        |||||||. |.|.|..|.              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

RISDFGLSRVVDNR----------------------MTKTVGTPCYMAVEVLKGLT---------------DYSQQADVYSFAFVLWECISRQIPYKDFA
 |.||||||.....                        . .|||..|| |||.| .               .||...|||||. ||||...|..||.|. 
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

QI---------QWISMVLEDSFRPPIP------------DSCLPEFRDLITMCWTSNPDDRPSFQQIITYL
 .         ....|| ... |||||            ..|.|....|...|| ..|..|||||.|. .|
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase DDB0229956.AA MLK 758-1005 31 6.1e-83 281.85 In-house 1-291 (291) Show / Hide 
Range on Protein: 758-1005
Range on HMM: 1-291/291
Sequence Identity: 31% (91 aa)

LELTKEIGRGVSGVVKRGKWKGYE-----IAVKQFN---EEELGFSE---REFHSEATIMSVLRHDN----IVHCVGGSAQPGK-MYLVCDYYSRGSLYS
... . || | .|.| .|.|.. .     .|||...   . . . ..   ..|  |. . ..|.| |    |.  .|...||..  ..|  | . ||||.
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

VITA-NI------------CPLSNARIVHLALQVAKGMNYLHSLG---IIHRDLKPGNLLIDQ------DWNIRISDFGLSRVVDNR---MTKTVGTPCY
|. . ..               . . ..  |||.|.||.||||.    |||||||. |.|||.      . . .|.|||.|| . ..   |... ||. .
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAW

MAVEVL--KGLTDYSQQADVYSFAFVLWECISRQIPYK-DFAQIQWISMVLEDSFRPPIPDSCLPEFRDLITMCWTSNPDDRPSFQQIITYL
|| ||.  .  . ||  .||.|.. |||| ..|..||| .  ... . .| . . ||||| .| . .  |...|| ..| .||||.||...|
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase DDB0229956.AA Dicty4 758-1007 39 9.8e-80 265.61 In-house 1-277 (277) Show / Hide 
Range on Protein: 758-1007
Range on HMM: 1-277/277
Sequence Identity: 39% (109 aa)

LELTKEIGRGVSGVVKRGKWKGYEIAVKQFNEEELGFSER---EFHSEATIMSVLRHDNIVHCVGGSA----QPGKMYLVCDYYSRGSLYSVITA-----
.  ...||.|  | | .|.|.| | ||| .|    .|.|    ||. |..||. .|| ||. . | .     .||||  |  | ..|.|||.. .     
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

-NICPLSNARIVH---LALQVAKGMNYLHS--LGIIHRDLKPGNLLIDQDWNIRISDFGLSR----VVDNRM-TKT-VGTPCYMAVEVLKGLTDYSQQAD
    .|.  .|     .|. .|.|||.||.    |||||||. |||.|..|.. ..|||||.    . |.   ..| .||||.|| ||. .   | . ||
QQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMH-QPYNEKAD

VYSFAFVLWECISRQIPYK-DFAQI-QWISMVLEDSFRPPIPDSCLPEFRDLITMCWTSNPDDRPSFQQIITY--LEN
||||. ||||.  ||.||   .  . | .  | .   ||||||.|.| ...||. ||  .|  ||||..|| .  || 
VYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase DDB0229956.AA Dicty5 758-1009 39 2e-75 256.87 In-house 1-260 (260) Show / Hide 
Range on Protein: 758-1009
Range on HMM: 1-260/260
Sequence Identity: 39% (103 aa)

LELTKEIGRGVSGVVKRGKWKGYEIAVKQFNEEE-LGFSEREFHSEATIMSVLR--HDNIVHCVGGSAQPGKM-YLVCDYYSRGSLYSVITANIC----P
  . . |  | || |  |  ||  .|.| .  |  ..|   ||  | ||||.    |.|.. | |   .  |  . |  | ..||| .           |
VSFHDWIASGASGRVYNGIYKGMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQP

LSNARIVHLALQVAKGMNYLHSLGIIHRDLKPGNLLIDQDWNIRISDFGLSRVVDNR--MTKTVGTPCYMAVEVLKGLTDYSQQADVYSFAFVLWECISR
..   ..|.|. .|..| .||| .|||||||  | ||  .| | | ||| || ||||  ||  |||.|.|| |. .| . | | .|||||. |||| . |
IAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQP-YHQKCDVYSFGIVLWEMFTR

QIPYKDFAQIQWISMVLEDSFRPPIPDSCLPEFRDLITMCWTSNPDDRPSFQQIITYLENLR
  ||.. ...    ||     || ||  |  |.  ||  ||.  |  ||||  |. |.| . 
KEPYDNINNWNIPVMVMKGE-RPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase DDB0229956.AA DRK 758-1007 38 1.3e-71 241.82 In-house 1-258 (258) Show / Hide 
Range on Protein: 758-1007
Range on HMM: 1-258/258
Sequence Identity: 38% (101 aa)

LELTKEIGRGVSGVVKRGKWKGYEIAVKQF---NEEELGFSEREFHSEATIMSVLRHDNIVHCVGGSAQPGKMYLVCDYYSRGSLYSVITANICPLSNAR
      ||||  | | || | | ..|||     |.... |   ||| |...|. ||| ||.   |    |     .  | .|||||..       ..  .
IKIGNRIGRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLN-EFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPL

IVHLALQVAKGMNYLHSLG--IIHRDLKPGNLLIDQDWNIRISDFGLSR----VVDNRMTKT-VGTPCYMAVEVLKGLTDYSQQADVYSFAFVLWECISR
.  ... .||||.|||.    |||||||  |||.|  | . ..|||||     . .   ..| .||||  | |||     |   ||||||| |||||. |
MKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRN-QRYTEKADVYSFAIVLWECVTR

QIPYKDFAQIQWISMVLEDSFRPPIPDSCLPEFRDLITMCWTSNPDDRPSFQQIITYLEN
|.||      | .  |  .  |||.|  | | .  |.. ||  .|  |||.|...  || 
QDPYFGMPTFQVVFSVGRHGMRPPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase DDB0229956.AA LRRK 758-1007 27 4.1e-70 239.25 In-house 1-351 (351) Show / Hide 
Range on Protein: 758-1007
Range on HMM: 1-351/351
Sequence Identity: 27% (98 aa)

LELTKEIGRGVSG-VVKRGKWKG----------------------------YEIAVKQFNEE-------------------------------ELGFSE-
|.  ..||||..| .| |.||.|                            ...|.|..| .                               . .... 
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

-REFHSEATIMSVLRHDNIVHCVGGSAQPGKMYLVCDYYSRGSLYSVITANI-CP-------LSNARIVHLALQVAKGMNYLHSLG--IIHRDLKPGNLL
 |||. |..||| |.|.|||  .| . .|  . .| .| . |.||... ..   .       .|   .  .|||.||||.||||    |||||||. | |
FREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNIL

I---D---------QDWNIRISDFGLSR---VVDNR-MTKTVGTPCYMAVEVLK--GLTDYSQQADVYSFAFVLWECISRQ-IPYKDFA---QIQWISMV
.   .         .. .. |.|||.||   .. .    . ||.| .|| |...  |   |....|.|||. .|||...|| .|. ..    ..||....
LWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQI

LE---DSFRPPIPDS-CLP-----EFRDLITMCWTSNPDDRPSFQQIITYLEN
 .   .  ||.|| . |.|     .. |||. ||. .|..||.|.||.  |. 
EDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase DDB0229956.AA Dicty4-Unclassified 758-1005 34 3.7e-65 222.08 In-house 1-263 (263) Show / Hide 
Range on Protein: 758-1005
Range on HMM: 1-263/263
Sequence Identity: 34% (92 aa)

LELTKEIGRGVSGVVKRGKWKGYEIAVKQFNEEELGFSER-----EFHSEATIMSVLRHDNIVHCVGGSAQP----GKMYLVCDYYSRGSLYSVIT----
.   ..||.|    | .| ||| ..||| |||    |. |     .|  |  |.  . | | | | | .  |      |  |     .| |  ||     
IQIDQFIGKGHFSKVHKGNWKGKDVAVKKFNENK--FKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPS

ANICPLSNAR--IVHLALQVAKGMNYLHSLGIIHRDLKPGNLLIDQDWNIRISDFGLSRVVDNRMTKT-VG-TPCYMAVEVLKGLTDYSQQADVYSFAFV
    |..     |.  |. .|.|| .||.  .||||.|  |.|.| . ||.| |||.|||.|.  . | .. ||   . |.|..   | | .||||.| .
EQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHES-YNQKSDVYSYAMM

LWECISRQIPYKDFA-QIQWISMVLEDSFRPPIPDSCLPEFRDLITMCWTSNPDDRPSFQQIITYL
|.| .    || .    .     | .   || |||.| . .. ||  ||   |  ||.. ||| ||
LYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase DDB0229956.AA S_TKc 758-1005 26 2.8e-64 220.79 SMART 1-231 (231) Show / Hide 
Range on Protein: 758-1005
Range on HMM: 1-231/231
Sequence Identity: 26% (70 aa)

LELTKEIGRGVSGVVKRGKWKG--YEIAVKQFNEEELGFSEREFHSEATIMSVLRHDNIVHCVGGSAQPGKMYLVCDYYSR--GSLYSVITANICP----
 |. ..||.|  |.|.....|.   . |.|. .        . . .|  |..  .|.|||.. .     ...|.| .| .   |.|...|  . ..    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LSNARIVHLALQVAKGMNYLHSLGIIHRDLKPGNLLIDQDWNIRISDFGLSRVVDNRMTKTVGTPCYMAVEVLKGLTDYSQ-QADVYSFAFVLWECISR
 ..  .. ... |......|.||.||||||||| |.|.|.  .| |.||||.|..    |  .||| ||| |||     |.   .|..|.  .|.|....
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCG

QIPYKDFAQIQWISMVLEDSFRPPIPDSCLPEFRDLITMCWTSNPDDRPSFQQIIT---------YL
. |.    |.| .  ..             ||..|.|  |.. .|..||.  .. .         ..
YPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DDB0229956.AA Pkinase 758-1005 27 5.9e-64 223.59 Pfam 1-293 (293) Show / Hide 
Range on Protein: 758-1005
Range on HMM: 1-293/293
Sequence Identity: 27% (82 aa)

LELTKEIGRGVSGVVKRGKWKGYE--IAVKQFNEEELGFSER--EFH-SEATIMSVLRHDNIVHCVGGSAQPGKMYLVCDYYSRG----SLYSVIT-ANI
... . ||.| .|.|.....||..   |||... ..   ...   .. ||. ||  |.|.||| . .    ....|.| .|   |    .|...|.  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

CPL--SNARIVHLALQVAKGMNYLHSLGIIHRDLKPGNLLIDQDWNI----RISDFGLSR---VVDNRMTKTVGTPCYMAVEVLKGLTDYSQQADVYSFA
...  |   . . ..|...|..|.|| ||||||||| |.|||.. .|    .|.||||..      |.||  .||| ||| ||..| ..|.. .|..|. 
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCG

FVLWECISRQIPYKDF------AQIQWISMVLEDSFRPPIPDSCL-------------------PEFRDLITMCWTSNPDDRPSFQQIITY--L
 .|.| .... |...        |.| | ....  .. ..| .|                    .|..|.|. |.. .| .||...||     .
CILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase DDB0229956.AA Pkinase_Tyr 758-1005 30 1.8e-60 205.4 Pfam 1-270 (270) Show / Hide 
Range on Protein: 758-1005
Range on HMM: 1-270/270
Sequence Identity: 30% (84 aa)

LELTKEIGRGVSGVVKRGKWK------GYEIAVKQFNEEELGFSE---REFHSEATIMSVL-RHDNIVHCVGGSA-QPGK--MYLVCDYYSRGSLYSVIT
... |..|.|  |.|..|.||      ... |||    |    ..   ..| .|| ||. | .|.||| ..|    | .   .|.|  |   |.|..   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

AN---ICPLSNARIVHLALQVAKGMNYLHSLGIIHRDLKPGNLLIDQDWNIRISDFGLSRVV--DNRM-TKTVGTPC---YMAVEVLKGLTDYSQQADVY
..     ||.  .... ..|.||||.||.| ..|||||   | |.. .  ..|.||||.| .  |    .|. |...    || |...    .. . ||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDVW

SFAFVLWECIS-RQIP-YKDFAQIQWISMVLEDSFRPPIPDSCLPEFRDLITMCWTSNPDDRPSFQQIITYL
||  ..|| ..  ..| |..    . . .. ||  | |.|. | .|  ||...||  .|.|||.|..|.  |
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase DDB0229956.AA TyrKc 758-1005 27 2.2e-58 201.18 SMART 1-280 (280) Show / Hide 
Range on Protein: 758-1005
Range on HMM: 1-280/280
Sequence Identity: 27% (80 aa)

LELTKEIGRGVSGVVKRGKWKGYEIAVKQFNEEELGFSEREFHSEATIMSVL--RHDNIVHCVGGSAQP-------GKMYLVCDYYSRGSLYSVITANIC
..| |..|.|  |.| .|.|| .. |||  .|.     ...|..|| ||. |  .|.||| ..|   |.       . ...|  | . |.| . . ..  
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

PLSNARIVHLALQVAKGMNYLHSLGIIHRDLKPGNLLIDQDWNIRISDFGLSRVVDNR-------MTKTV----GTP--C---YMAVEVLKGLTD-YSQQ
 |...  .. ..|.|.||.|||| ..|||||   | |.. .  ..|||||||| ...         ....    |.        || |..   .  .. .
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYGKFTTK

ADVYSFAFVLWECISR-QIPYKD----FAQIQWISMVLEDSFRPPIPDS--------CLPEFRDLITMCWTSNPDDRPSFQQIITYL
 ||.||  ..||  .. | || .    .   | .   ... .|.|.|..        | .|  .....||  .|.|||.|..|. ..
SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase DDB0229956.AA TK 758-1005 16 7.6e-56 185.32 In-house 1-486 (486) Show / Hide 
Range on Protein: 758-1005
Range on HMM: 1-486/486
Sequence Identity: 16% (82 aa)

LELTKEIGRGVSG---VVKRGKWKG---------------------------YEIAVKQFN----EEELGFSEREFH---------SEATIMSVLR----
..| |..|.|  |   .| .|.|.|                            . |||.      ...  | ..|.|         .|| .|....    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HDNIVHCVGGSAQP------------GKMYLVCDYYSRGS----LYSVITANICP--------------------------------------------
 |.|||...| . |.            . ...|  | . |.    | .   ..  .                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LSNARIVHLALQVAKGMNYLHSL------GIIHRDLKPGNLLIDQDWN-----------IRISDFG---
                               |. .. .  ..|.|.|| ||||.      ...||||   | |.... .           ..|.|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LSRVVDN----RMTKTVGTPC-------------------------YMAVEVLKGLT--------DYSQQADVYSFAFVLWECIS--RQIPYK-D
     |.| ...    . ... ||..                         .|| |.|.. .         .. . ||.||  ..||. .  .. .|   
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

FAQIQWI----SMVLEDS-----------------FRPPIPDSCL--------------PEFRDLITMCWTSNPDDRPSFQQIITYL
  |  |.      |.|                   .|.| |. |               .|. ||...||  .|.|||.|.|.  .|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase DDB0229956.AA STE 758-1000 21 2.9e-50 173.29 In-house 1-350 (359) Show / Hide 
Range on Protein: 758-1000
Range on HMM: 1-350/359
Sequence Identity: 21% (76 aa)

LELTKEIGRGVSGVVKRGKWK-----------------GYEIAVKQFNEEELG----------------FSEREFHSEATIMSVLR--HDNIVHCVGGSA
.|. ..||.| .|.| ... .                 |  .|.|| | |.                    . ..  |  ||. ..  |.|||.. |   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

QPG-------KMYLVCDYYSRGSLYSVITAN-ICPLS------------NARIVHLALQVAKG-MNYLHSLGIIHRDLKPGNLLIDQDWNIRISDFGLSR
. |       . ...  | . ||| ..|  . .|. .               | . . |. || ..||||..|||||.||.| |.     . ..|||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

VVDN-------------------RMTKTVGTPCYMAVEVLKG-----LTDYSQQADVYSFAFVLWECISRQIPYKDFAQIQWISMVLED-----------
 ...                   . .  |||| .|| ||...       .|. ..|..|.  ...| .  . |. |.   . . | .             
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---SFRPPIPD-------------------SCLPEFRDLITMCWTSNPDDRPSFQQ
      ||.||                   .. |||.| |  | . .|..||. .|
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ