Gene DDB0230038 (Slime mold)

DDB0230038

Species: Slime mold
Alias: DdisK191, DDB0230038
External Links: DictyBase Link ,
Annotation:

Classification

Group: TKL
Family: ARMK

Sequence

Name Sequence Type Origin Length Description Download
DDB0230038.AA Protein None 1192 None Fasta, JSON
DDB0230038.kin_dom Protein Kinase Domain None 250 None Fasta, JSON

Protein domain

Protein domains of DDB0230038.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0230038.AA ARMK 522-785 58 1.6e-200 672.43 In-house 2-295 (362) Show / Hide 
Range on Protein: 522-785
Range on HMM: 2-295/362
Sequence Identity: 58% (171 aa)

QPSDIIGSGNNGTTQRAGIHKDKRIVMKQWN-FITSQATPMLFNEIEQLVAIKHPNILALAGASFDNQTFTTFTEYITGSNLDIVIKNLDEKNE------
|  |.|||||.|...||.||||||||||||| |.|.|.|||.||||.|...|.||||....|..||||.......|.|..|.|||.|.....|.      
QVGDRIGSGNFGDCYRANIHKDKRIVMKQWNQFFTDQFTPMFFNEIMQIREIQHPNIVPVSGCCFDNQIYIVHPYYDTSNNQDIVFKQSHNNNNNNNNNN

--------------------LQLILRLSEEIASAMSFLHSFNIVHRSLHPKNILLN-SDLKIYIKDYGFTSLKDETLKKKFMSFQLKNQLLHTQYLAPEL
                    .|.|.|.||||..||..|||.|||||||||.|||.| .|..|||.||||...|||...||||||||||||||||||||||
NNNNNNNNNNNNNNNHTIISNQFIHRVSEEISKAMTYLHSHNIVHRSLHPNNILINRVDGNIYIRDYGFNFVKDEIFRKKFMSFQLKNQLLHTQYLAPEL

FNVLSGSKGGYDTKVDVFSFGVLLWEMFARDIKLSDLKSNTVNG-YTHYLRPPLPN-CPFTIEKLIKLCLSTDPSVRPTFTTILKILRQPLHTI
|||...|||.|||.||.|||...||.||.||||..|...|..|. ||||.|||.|| |||..|.|||.|.||||||||||||| ||| ||   |
FNVNCNSKGQYDTNVDQFSFAMILWQMFTRDIKFQDIHVNRINDTYTHYVRPPIPNNCPFVFERLIKACWSTDPSVRPTFTTISKILSQPFQRI
Kinase DDB0230038.AA TKL 527-778 19 3.2e-65 222.99 In-house 1-364 (364) Show / Hide 
Range on Protein: 527-778
Range on HMM: 1-364/364
Sequence Identity: 19% (74 aa)

IGSGNNGTTQRAGIHKD----------KRIVMKQWNF---------------------------ITSQATPMLFNEIEQLVAIKHPNILALAGASFDNQT
||||  | .   |...           | ...|...                             .|..   . .|| ..  ..||||. . |...... 
IGSGGFG-EVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPC

-------------FTTFTEYITGSN-LDIVIKNLDEKNELQLILRLSEEIASAMSFLHSFN--------IVHRSLHPKNILLNSDLK-------------
             .   .||. | . |....        .....|.. .||..|..||| |        |.|| | .||||......             
GCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-IYIKDYGFTSLKDETLKKKFMSF-------------QLKNQLLHTQYLAPELFNVLSGSK-----------GGYDTKVDVFSFGVLLWEMFARDIKLSD
 . | |.|.   .... ... ..              .. .|  .....|||...     .           . |..|.||.|||..|||...| .  .|
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYD

LKSNT-----------VNGYTHYLRPPLP-------------NCPFTIEKLIKLCLSTDPSVRPTFTTILKIL
.....           .  . . ||||.|             .||  . ||.. | ..||. ||.|..|||.|
YPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase DDB0230038.AA TKL-Unique 523-778 24 1.1e-42 148.19 In-house 1-290 (290) Show / Hide 
Range on Protein: 523-778
Range on HMM: 1-290/290
Sequence Identity: 24% (72 aa)

PSDIIGSGNNGTTQRAGIHKDKRIVMKQWNF---ITSQATPMLFNEIEQLVAIK-HPNILALAGASF----DNQTFTTFTEYITGSNLDIVIK-------
..  ||.|  |.  . |... . . .|| ..   . .. .  . ||.  .  .. ||||. . |...    ..  .  ..||. |..|. |.        
FWNKIGEGGYGQVYK-GKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--NLDEKNELQLILRLSEEIASAMSFLHSFN--IVHRSLHPKNILLNSD-----LKIYIKDYGFTSLKDETLKKKFM----SFQLKNQLLH--TQYLAPE
  |   |. .|..... . ||..| .||. .  | || | ..|.|....     ..| | | |.  ...  .|...     .    ||     ....|||
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTR---NQTRCGSFRWMAPE

LFNVLSGSKGGYDTKVDVFSFGVLLWEMFARDI---------KLSDLKSNTVNGYT-HYLRPPL-PNCPFTIEKLIKLCLSTDPSVRPTFTTILKIL
... .      |..|.||.|||. |||.. |.|         .... .   .  |.   .|||. ..||  . .||. |   ||| ||.|..|.. |
VLRMNF---CQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase DDB0230038.AA LRRK 23-780 9 4.5e-34 117.91 In-house 66-351 (351) Show / Hide 
Range on Protein: 23-780
Range on HMM: 66-351/351
Sequence Identity: 9% (79 aa)

STINLNNNNSNNNNNNNNNGNSATKISFQEQMPNGNGNSSTTTTTAAQQSATEKRKSRLSQHPSNLNEGGFDYLDTLLNDMSDESIRNSIKTDNSRIKSL
.. |  .|||||||| |||.                                                                                
ID-ND-CNNSNNNNNLNNNN--------------------------------------------------------------------------------

RLTSTFDLESTLKDLEETFMKDSSIQNKRKPSSYLSKNLSPPSNPSNIISNNNASTLPLPPPPSQQDDVVIIAKLPPPVSISLPPPPTTEELPLPPPSTE
                                                                                                    
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ELQLPPPPPTTTTADEQILTDSVKNGNPILKRVSSERAIILTKEAIDAADLLDEMIESFGGIPEPNGNNSLPKEIKTTSIPTPIVTPSTTTSTNTTTAAT
                                                                                                    
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VNKLNASKSPNGTLTTRPAAKLGAPVDIQVSSPKAPTPIPTLSSPSPSQSAAPQPAAPQPTPTSQPQPPTTTVSTPVSPTFKDSDQLLDDMISHFKESNS
                                                                                                    
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NLLTSSSNLDPSAPKVVYTSQQFYPLSVEEQSLQSKVKVQLTPDEQVIQKILGNNDLDDDITNKNNDNNSNGNNNNKELIDEQNQIEQQQSDKSWYIKAQ
                                                                                                    
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PSDIIGSGNNGTTQRAGIHKDKRIVMKQWNFI------TSQATPMLFNEIEQLVAIKHPNILALAGASFDNQTFTTFTEYITGSNLDIVIKNLDEKN---
                           | ...      .. |   . .|.  .   .||||. | | ...  ..   .||..  .|. ...|  .     
-------------------------SEQVEDMDQNHEDCCRAFREFRHEVWIMSHLNHPNIVSLKGFCIHPLCM--VMEYAPHGDLYHFLHNKKQDGFHF

---E--LQLILRLSEEIASAMSFLHSFN--IVHRSLHPKNILLNSD----------LKIYIK--DYGFTSLKDETLKKKFMSFQLKNQLLHTQYLAPELF
   .   .|.|... .||..| .|||.|  |.|| | . ||||.|             . .|  |.| ...   ...... .. . |     ...|||  
MKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNP----GWMAPE--

NVLSGS-KGGYDTKVDVFSFGVLLWEMFARD-IKLSDLK-------SNTVNG-YTHYLRPPLP-N-CPF-----TIEKLIKLCLSTDPSVRPTFTTILKI
 .. .  .  |..|||..|||..|||   |. .   ...        ...    .  |||..| . ||        ..||..| ..||  ||.|..|.|.
-IMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKR

LRQ
| |
LSQ
Kinase DDB0230038.AA TK 21-778 6 1.1e-32 106.3 In-house 82-486 (486) Show / Hide 
Range on Protein: 21-778
Range on HMM: 82-486/486
Sequence Identity: 6% (66 aa)

GQSTINLNNNNSNNNNNNNNNGNSATKISFQEQMPNGNGNSSTTTTTAAQQSATEKRKSRLSQHPSNLNEGGFDYLDTLLNDMSDESIRNSIKTDNSRIK
|                                                                                                   
G---------------------------------------------------------------------------------------------------

SLRLTSTFDLESTLKDLEETFMKDSSIQNKRKPSSYLSKNLSPPSNPSNIISNNNASTLPLPPPPSQQDDVVIIAKLPPPVSISLPPPPTTEELPLPPPS
                                                                                                    
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TEELQLPPPPPTTTTADEQILTDSVKNGNPILKRVSSERAIILTKEAIDAADLLDEMIESFGGIPEPNGNNSLPKEIKTTSIPTPIVTPSTTTSTNTTTA
                                                                                                    
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ATVNKLNASKSPNGTLTTRPAAKLGAPVDIQVSSPKAPTPIPTLSSPSPSQSAAPQPAAPQPTPTSQPQPPTTTVSTPVSPTFKDSDQLLDDMISHFKES
                                                                                                    
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NSNLLTSSSNLDPSAPKVVYTSQQFYPLSVEEQSLQSKVKVQLTPDEQVIQKILGNNDLDDDITNKNNDNNSNGNNNNKELIDEQNQIEQQQSDKSWYIK
                                                                                                    
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AQPSDIIGSGNNGTTQRAGIHKDKRIVMKQWNFITSQATPM----LFNEIEQLV--AIKHPNILALAGASFDNQT------------FTTFTEYITGSN-
                                        .    . .|....   . .||||. | |.......            .   .||  . . 
----------------------------------------EDFLEEAEEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDM

---LDIVIKNLDEKNE---------------------------------------------------------------------------LQLILRLSE
   |.   .. ..|                                                                             ..  |  . 
DGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCW

EIASAMSFLHSF------NIVHRSLHPKNILLNSDLK-----------IYIKDYGFT------SLKDETLKKKFMSFQLK--------------------
 ||..|..|||       |.||| |   |.|......           . | |.| .        .|   ..   . . .                    
QIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQ

--NQLLHTQYLAPELFN--VLSGS--KGGYDTKVDVFSFGVLLWEMFARD-IKLSDLKSN---------------TVNGYTH-----------YLRPPLP
  .  |   ..||| .|  | | .  .| . || ||.|||||.||.| .         ||                ..| ..           . .|. |
QSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPP

NCP--------------FTIEKLIKLCLSTDPSVRPTFTTILKIL
.||                .. |.. | . ||. ||||..... |
HCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase DDB0230038.AA RAF 521-780 25 3e-23 71.98 In-house 1-282 (282) Show / Hide 
Range on Protein: 521-780
Range on HMM: 1-282/282
Sequence Identity: 25% (72 aa)

AQPSDIIGSGNNGTTQRAGIHKD---KRIVMKQWNFITSQATPMLFNEIEQLVAIKHPNILALAGASFDNQ--TFTTFTEYITGSNLDIVIKNLDE--KN
 . .  ||||  ||  |.. | |   |.. ...      ||  .  ||.  .    | |||   | . . |  |.   |..  .| |   |   .   | 
VMVMTRIGSGSFGTVYRGHWHGDVAVKMLNVNDPTPEQMQADVFFKNEVAVYKKTRHCNILLFMGYMSKPQTNTYAIVTQWCEHSSLYHHIHVQETREKF

ELQLILRLSEEIASAMSFLHSFNIVHRSLHPKNILLNSDLKIYIKDYGFTSLKDETLKKKFMSFQLKNQLLHTQYLAPELFN---------VLSGSKGGY
... ..  |  .. .|..||. ||.|| |  .||.|  |... | |.|   .|     .    |.  .      ..|||            ||   .  |
DMHWLIDISRQVCQGMDYLHAKNIIHRDLKSNNIFLHEDMTVKIGDFGLMTVKTRWSPRGNQQFEQPTHWI--LWMAPEVIRNLMIDWRGDVLMQDENPY

DTKVDVFSFGVLLWEMFARDIKL-SDLKSNTVNGY---THYLRPPL----PNCPFTIEKLIKLCLSTDPSVRPTFTTILKILRQ
  . ||.|||. ..|. .| .   .. ..     .     |||| |     .||  . .|.. |.. ..  || |  ||| .  
SFQSDVYSFGIVMYELMTRHMPYGCHIWNRDQIIFMCGRGYLRPDLSKVRQDCPKAMHRLMEDCWKFQREERPLFQQILKRITV
Kinase DDB0230038.AA S_TKc 521-783 23 9.7e-20 72.82 SMART 1-231 (231) Show / Hide 
Range on Protein: 521-783
Range on HMM: 1-231/231
Sequence Identity: 23% (64 aa)

AQPSDIIGSGNNGTTQRAGIHKD--KRIVMKQWNFITSQATPMLFNEIEQLVAIKHPNILALAGASFDNQTFTTFTEYITG--SNLDIVIKNLDEKN---
 .  ..||.|  |.  .. .||.  ..  .|. .        .. .||. |   .||||  | ..  | . .  ..||. |   .|  .||.   .    
YEILRKIGKGAFGKVYKC-RHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

--ELQLILRLSEEIASAMSFLHSFNIVHRSLHPKNILLNSDLKIYIKDYGFTSLKDETLKKKFMSFQLKNQLLHT-QYLAPELFNVLSGSKGGYDT-KVD
      . ..  .|..|. ..|| .|.|| | | ||||..   | | | |.  .               . .  |  |.|||..        ||.. |.|
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------------TTFCGTPWYMAPEVL--------GYGKCKCD

VFSFGVLLWEMFARDIKLSDLKSNTVNGYTHYLRPPLPNCPFTIEKLIKLCLSTDPSVRPTFTTILK----ILRQPLH
. |.|..|.||...    .     ...   . ..      .     .|. ||  ||. |||   .|.    |   |  
WWSCGCILYEMLCGYPPFP-----QMQMMFKKIG------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DDB0230038.AA MLK 704-778 34 1.4e-19 64.72 In-house 213-291 (291) Show / Hide 
Range on Protein: 704-778
Range on HMM: 213-291/291
Sequence Identity: 34% (27 aa)

YDTKVDVFSFGVLLWEMFARDIKLS-DLKSNTV---NGYTHYLRPPLPNCPFTIEKLIKLCLSTDPSVRPTFTTILKIL
|. |.||.|.||.||||..| .  . .... ..   ..|..  .|  ..||  ..||.| | ..||. ||.|  |...|
YSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase DDB0230038.AA STE 27-777 8 4e-19 64.26 In-house 19-359 (359) Show / Hide 
Range on Protein: 27-777
Range on HMM: 19-359/359
Sequence Identity: 8% (69 aa)

LNNNNSNNNNNNNNNGNSATKISFQEQMPNGNGNSSTTTTTAAQQSATEKRKSRLSQHPSNLNEGGFDYLDTLLNDMSDESIRNSIKTDNSRIKSLRLTS
.|..|.|..  .... |                                                                                   
MNHKNCNIH-KTGEVEN-----------------------------------------------------------------------------------

TFDLESTLKDLEETFMKDSSIQNKRKPSSYLSKNLSPPSNPSNIISNNNASTLPLPPPPSQQDDVVIIAKLPPPVSISLPPPPTTEELPLPPPSTEELQL
                                                                                                    
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PPPPPTTTTADEQILTDSVKNGNPILKRVSSERAIILTKEAIDAADLLDEMIESFGGIPEPNGNNSLPKEIKTTSIPTPIVTPSTTTSTNTTTAATVNKL
                                                                                                    
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NASKSPNGTLTTRPAAKLGAPVDIQVSSPKAPTPIPTLSSPSPSQSAAPQPAAPQPTPTSQPQPPTTTVSTPVSPTFKDSDQLLDDMISHFKESNSNLLT
                                                                                                    
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SSSNLDPSAPKVVYTSQQFYPLSVEEQSLQSKVKVQLTPDEQVIQKILGNNDLDDDITNKNNDNNSNGNNNNKELIDEQNQIEQQQSDKSWYIKAQPSDI
                                                                                                    
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IGSGNNGTTQRAGIHKDKRIVMKQWNFITS-----------------QATPMLFNEIEQLVAIK--HPNILALAGASFDN-------QTFTTFTEYITGS
             ... ... .|| |. ..                 .    . .||. .   .  ||||    |. |..       ..   . ||. | 
------------NGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGG

NLDIVIKNLDEKNE-------------LQLILRLSEEIASA-MSFLHSFNIVHRSLHPKNILLNSDLKIYIKDYGFTSLKDE---------------TLK
 || .||.  ....              ..| .   .|  . ...||| .|.|| . | ||||     . . | |. .  ..               | .
SLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQ

KKFMSFQ-LKNQLLHTQYLAPELFNVLSGS-KGGYDTKVDVFSFGVLLWEMFARDIKLSDLKSNTVNGYTH----------------YLRPPLPN-----
.|  .|           . |||  .  ... ..|||||.|. |.| ...||      ..|..   .  ..                    ||||.     
QKRNTFVGTP-------WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQN

---------------CPFTIEKLIKLCLSTDPSVRPTFTTILK-----I
               .       |..||  ||. ||| .  ||     |
EMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase DDB0230038.AA TK-Unique 561-721 25 9.6e-17 54.36 In-house 49-233 (294) Show / Hide 
Range on Protein: 561-721
Range on HMM: 49-233/294
Sequence Identity: 25% (48 aa)

MLFNEIEQLVAIK-HPNILALAGASFDNQ-TFTTFTEYITGSNLDIVIK-------------NLD----------EKNELQ--LILRLSEEIASAMSFLH
....||... ... ||||. . |.. ...  .    ||. ..||.  ..             ||.          ......  . ..   .||..|..|.
DFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLA

S--FNIVHRSLHPKNILLNSDLKIYIKDYGFTS-LKDETLKKKFMSFQLKNQLLHTQYLAPELFNVLSGSKGGY-DTKVDVFSFGVLLWEMF
|   .|||| |  .|.||..|... | |.|..  . .     .  | . . . ..  ..||| .      .| |  || || |||||.||.|
SQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT----NGVYSMMCSQGRIPIRWMAPESLKCY---HGMYHTTKSDVWSFGVLMWEIF
Kinase DDB0230038.AA TyrKc 521-778 20 3.8e-15 22.19 SMART 1-280 (280) Show / Hide 
Range on Protein: 521-778
Range on HMM: 1-280/280
Sequence Identity: 20% (61 aa)

AQPSDIIGSGNNGTTQRAGIHKDKRIVMKQWNFITSQATPMLFNEIEQLVAI--KHPNILALAGASFDN-------QTFTTFTEYITGSNLDIVIKNLDE
 .  ...|.|. |.  ..          |  .  .     .. .|.. .  .  .||||..| |.  .        .     .||  . .|.  ...  .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

KNELQLILRLSEEIASAMSFLHSFNIVHRSLHPKNILLNSDLKIYIKDYGFTSLKDET-------LKKKFMSFQLKNQLLHTQYLAPELFNVLSGSKGGY
|  ..  |  .  ||. |..||| |..|| |   |.|..... . | | | .   ..          .. .. . .. .|    .||| .      .| .
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-----NYGKF

DTKVDVFSFGVLLWEMFAR------D-----IKLSDLKSNTVNGYTHYLRPPLPN-------CPFTIEKLIKLCLSTDPSVRPTFTTILKIL
 || ||.||||..||.| .      .     .. ...  .  .||  ....|  .       ||  . ...| |   ||. ||||..| ...
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGY--RMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase DDB0230038.AA Pkinase 521-778 20 7.4e-15 53.62 Pfam 1-293 (293) Show / Hide 
Range on Protein: 521-778
Range on HMM: 1-293/293
Sequence Identity: 20% (64 aa)

AQPSDIIGSGNNGTTQRAGIHKDKR--IVMKQWNFITSQATPMLF------NEIEQLVAIKHPNILALAGASFDNQTFTTFTEYITGS----NLDIVIK-
 .   .||||. |.  . ..||. .   ..|.  .  . . .         .||. .  ..||||. | ..  |..     .||  |      |  .|. 
YHIGRKIGSGSFGCV-YKCHHKGTGKIVAVKI--IKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

NLDEKN--ELQLILRLSEEIASAMSFLHSFNIVHRSLHPKNILLNSDLKI----YIKDYGFTSLKDETLKKKFMSFQLKNQLLHTQ-----YLAPELFNV
  . .   . . . .   .|.... ..|| .|.|| | | |||....  |     | | |.  ..|            .|. ..|      |.|||. . 
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----------Y-NNS-MTTFCGTPWYMAPEVIR-

LSGSKGGYDTKVDVFSFGVLLWEMFA------RD----IKLSDLKSNTVNGYTHYLRPPLPNCP-------------------FTIEKLIKLCLSTDPSV
   .  .|..|||..|.|..|.||.        .      .....    .... . ..    |.                    .  ..|| ||  ||. 
---GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKK

RPTFTTILKI--L
|||.. ||.   .
RPTAEQILQHPWF
Kinase DDB0230038.AA MLK 565-649 24 2.4e-13 42.78 In-house 55-160 (291) Show / Hide 
Range on Protein: 565-649
Range on HMM: 55-160/291
Sequence Identity: 24% (26 aa)

EIEQLVAIKHPN----ILALAGASFDN-QTFTTFTEYITGSNLDIVIKNLDEKNE-------------LQLILRLSEEIASAMSFLHSFN---IVHRSLH
|...|  ..|||    | .. |.. .. . |   .||. |. |  |... . | .             ...... .  .|..|..|||     |.|| | 
ECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLK

PKNILL
..|||.
SHNILI
Kinase DDB0230038.AA Dicty5 688-724 48 2.9e-12 38.51 In-house 169-200 (260) Show / Hide 
Range on Protein: 688-724
Range on HMM: 169-200/260
Sequence Identity: 48% (18 aa)

YLAPELFNVLSGSKGGYDTKVDVFSFGVLLWEMFARD
. |.||||       .|. |.||.|||. |||||.|.
WMACELFNGQ-----PYHQKCDVYSFGIVLWEMFTRK
Kinase DDB0230038.AA Dicty5 617-661 42 1e-09 29.65 In-house 105-149 (260) Show / Hide 
Range on Protein: 617-661
Range on HMM: 105-149/260
Sequence Identity: 42% (19 aa)

LILRLSEEIASAMSFLHSFNIVHRSLHPKNILLNSDLKIYIKDYG
..| .   || .| .||| ||.|| |   |.|.. ..|| | |.|
QQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFG
Kinase DDB0230038.AA TK-Unique 747-778 30 5.8e-07 20.19 In-house 262-294 (294) Show / Hide 
Range on Protein: 747-778
Range on HMM: 262-294/294
Sequence Identity: 30% (10 aa)

PNC-PFTIEKLIKLCLSTDPSVRPTFTTILKIL
..| . .. .|.| |.. .|. ||.|..|...|
EHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase DDB0230038.AA Pkinase_Tyr 689-721 48 2e-06 22.42 Pfam 181-208 (270) Show / Hide 
Range on Protein: 689-721
Range on HMM: 181-208/270
Sequence Identity: 48% (16 aa)

LAPELFNVLSGSKGGYDTKVDVFSFGVLLWEMF
.||| .|        . || || |||||.||.|
MAPECINYGK-----FTTKSDVWSFGVLMWEIF
Kinase DDB0230038.AA Dicty5 743-782 39 2e-06 17.89 In-house 220-260 (260) Show / Hide 
Range on Protein: 743-782
Range on HMM: 220-260/260
Sequence Identity: 39% (16 aa)

RPPLP-NCPFTIEKLIKLCLSTDPSVRPTFTTILKILRQPL
|| .|  || .| .||| |    |. ||.|. |.|....  
RPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase DDB0230038.AA Pkinase_Tyr 744-778 45 6e-06 20.79 Pfam 236-270 (270) Show / Hide 
Range on Protein: 744-778
Range on HMM: 236-270/270
Sequence Identity: 45% (16 aa)

PPLPNCPFTIEKLIKLCLSTDPSVRPTFTTILKIL
|. .|||  | .|.|.|   ||. ||||. |. .|
PCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase DDB0230038.AA Pkinase_Tyr 561-655 21 1e-05 20.03 Pfam 49-150 (270) Show / Hide 
Range on Protein: 561-655
Range on HMM: 49-150/270
Sequence Identity: 21% (22 aa)

MLFNEIEQLVAI-KHPNILALAGASF-DNQT--FTTFTEYITGSNLDIVIKNL---DEKNELQLILRLSEEIASAMSFLHSFNIVHRSLHPKNILLNSDL
....|.. .  . .||||. | |.   . .       .||  . .|.   ..    ...  .. .|  . .||..|..|.| |..|| |  .|.|.....
DFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENN

KI
..
VV
Kinase DDB0230038.AA HEAT 752-768 29 27.161201 1.41 Pfam 1-17 (31) Show / Hide 
Range on Protein: 752-768
Range on HMM: 1-17/31
Sequence Identity: 29% (5 aa)

TIEKLIKLCLSTDPSVR
 .. |.|.. ..|..||
ILPHLLKCLNDPDWEVR
HEAT DDB0230038.AA HEAT 905-935 19 0.231106 8.58 Pfam 1-31 (31) Show / Hide 
Range on Protein: 905-935
Range on HMM: 1-31/31
Sequence Identity: 19% (6 aa)

FVPLIFQLMDQPYDEIQLSCLKQFSTLIEHN
..|....... | .|....... ...|.|| 
ILPHLLKCLNDPDWEVREAACWCLGQLCEHC
Arm DDB0230038.AA Arm 893-921 31 0.842218 6.33 Pfam 1-29 (41) Show / Hide 
Range on Protein: 893-921
Range on HMM: 1-29/41
Sequence Identity: 31% (9 aa)

NVENIEYLLEADFVPLIFQLMDQPYDEIQ
| |........  ||.. ||.. |  |.|
NPEQKQAVIQCGCVPPLVQLLHHPDEEVQ
Arm DDB0230038.AA Arm 947-975 17 2.87403 4.51 Pfam 13-41 (41) Show / Hide 
Range on Protein: 947-975
Range on HMM: 13-41/41
Sequence Identity: 17% (5 aa)

GINILMETLNSQKENILFITLRLLSQLSN
.. .|.. |....|....  .. |. |. 
CVPPLVQLLHHPDEEVQENACWALWNLCA
HEAT DDB0230038.AA HEAT 947-977 19 39.395642 0.85 Pfam 1-31 (31) Show / Hide 
Range on Protein: 947-977
Range on HMM: 1-31/31
Sequence Identity: 19% (6 aa)

GINILMETLNSQKENILFITLRLLSQLSNGA
 ...|.. ||.. ...   ... |.||.  .
ILPHLLKCLNDPDWEVREAACWCLGQLCEHC
Arm DDB0230038.AA Arm 979-1019 26 1.1e-07 29.84 Pfam 1-41 (41) Show / Hide 
Range on Protein: 979-1019
Range on HMM: 1-41/41
Sequence Identity: 26% (11 aa)

REENREQILIKGGIPLLINLLSHQNELIRLQILWCLTLLLE
 .|......  |..|.|..||.|..| .. . .|.|. |  
NPEQKQAVIQCGCVPPLVQLLHHPDEEVQENACWALWNLCA
HEAT DDB0230038.AA HEAT 991-1021 29 0.003046 15.09 Pfam 1-31 (31) Show / Hide 
Range on Protein: 991-1021
Range on HMM: 1-31/31
Sequence Identity: 29% (9 aa)

GIPLLINLLSHQNELIRLQILWCLTLLLESN
 .|.|...|..... .|.. .|||. |.|  
ILPHLLKCLNDPDWEVREAACWCLGQLCEHC
Arm DDB0230038.AA Arm 1151-1182 21 7.744377 3.04 Pfam 1-32 (41) Show / Hide 
Range on Protein: 1151-1182
Range on HMM: 1-32/41
Sequence Identity: 21% (7 aa)

NPIHIPYLKSSNIIEP-LQYLKSSPHPSIQKAV
|| .. ..  .....| .| |. .|....|...
NPEQKQAVIQCGCVPPLVQLLH-HPDEEVQENA