Gene Gdt2 (Slime mold)

Gdt2

Species: Slime mold
Alias: DdisK213, Gdt2, DDB0220631
External Links: DictyBase Link ,
Annotation:

Classification

Group: TKL
Family: Gdt

Sequence

Name Sequence Type Origin Length Description Download
Gdt2.AA Protein None 1637 None Fasta, JSON
Gdt2.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of Gdt2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Gdt2.AA Gdt 1290-1542 49 1.2e-185 623.04 In-house 1-289 (289) Show / Hide 
Range on Protein: 1290-1542
Range on HMM: 1-289/289
Sequence Identity: 49% (142 aa)

IIIKNYISEGTFGIVYRGIWRSSPVAVKLLKNEYVD--------HDEIEKEISLLERLRHPNILLYVGRFIFSGIHGIVTDYCSKGCLSKYIHENK----
|..|.|.|.||||.||.||||||.||||..|..||.        .|||..|...|....|.||....|...||..|.|||.||..|.|..|||..|    
IDFKEYCSQGTFGMVYKGIWRSSQVAVKMFKHHYVNYTKTYSQSCDEIYREMDILSKIKHQNIVSFIGCVHFSSHHCIVTEYCPRGSLGYYIHQKKNQKK

------------------------YKITIIQKIRILIDISKACAYLHRNGITHRDLKPENILITSLNPKSLVCAKVSDFGTSKETNERYNLQTRRGTVAY
                        .|...||||||.|||.|.|..||.|||.||||||.||||.|.|..|.||||..|||||||.||.....|..||..|
SNTNTITNTITNTNTNTNTSTSTSIKMSMIQKIRIMIDIAKGCQFLHQNGIIHRDLKPDNILIFSTNENSEVCAKICDFGTSKEINEFHCKNTNCGTMNY

MSNEILSQGSYTKSTDIYSFGMLCYELFSERIPYYSEPHWRIRELVLKNERPSLDQEIFKDTDISDIVTRCWSKNPSQRPTFDYLSKYL
|||||.....|.||||.||||.|.||...||||.....||.|...|....||.|||.||.|.||..|...||.|||..|||||..|| |
MSNEIFEGENYQKSTDVYSFGILFYEMMIERIPFHEICHWEIPNFVQDGWRPTLDQDIFDDNDIRNIIECCWNKNPHKRPTFDEISKHL
Kinase Gdt2.AA TKL 1296-1542 23 1.6e-89 303.73 In-house 1-364 (364) Show / Hide 
Range on Protein: 1296-1542
Range on HMM: 1-364/364
Sequence Identity: 23% (87 aa)

ISEGTFGIVYRGIWRS----------SPVAVKLLKNEYVDH----------------------------DEIEKEISLLERLRHPNILLYVGRFIFSGI-
| .|.||.||.|.||            .|||| .| ...|                             ...|.|| .. |||||||....|  . ..  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------HGIVTDYCSKGCLSKYIHENKYKITIIQKIRILIDISKACAYLHRNG--------ITHRDLKPENILITSL---------NPKSLVCA
            ..||..||..|.|  |.|       . |..|. .||.....||| ..        | |||||..|||. .          ||.. .|.
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KVSDFGTSKETNERYN--------------------LQTRRGTVAYMSNEILS----------------QGSYTKSTDIYSFGMLCYELFSERIPYYSEP
|..|||.|.. ... |                    . |..|| ..|. |.|                 ...|....|.||||.. .|... ..||| .|
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

H----------WRIRELVLKNERPSLD----------QEIFKDTDISDIVTRCWSKNPSQRPTFDYLSKYL
.          . .   ..|..|| ..          ..   ....... ..||. .|..||.|. . |.|
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase Gdt2.AA TKL-Unique 1292-1542 30 2.1e-64 220.29 In-house 1-290 (290) Show / Hide 
Range on Protein: 1292-1542
Range on HMM: 1-290/290
Sequence Identity: 30% (89 aa)

IKNYISEGTFGIVYRGIWRSSPVAVKLLK-NEYVDHDEIE---KEISLLERLR-HPNILLYVGRFI----FSGIHGIVTDYCSKGCLSKYIH--------
. | | ||..| ||.|.||..|||.| .. || .  ....   .|......|. ||||..|.|  .      .   ||..||. | | ...|        
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

-ENKYKITIIQKIRILIDISKACAYLHRNG--ITHRDLKPENILITSLNPKSLVCAKVSDFGTSKETNER----YN-L-----QTRRGTVAYMSNEILSQ
 .|..|..  |.... |||.... |||...  |.|||||. |.|... ..   . .|..|||.||  . .    .| .     ||| |.  .|. |.|..
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--GSYTKSTDIYSFGMLCYELFSERI------PYYSEPHWRIRELVLK---NERPSLDQEIFKDTDISDIVTRCWSKNPSQRPTFDYLSKYL
    |... |.||||.  .|...  |      || .  .  ..|.| .   | || . ... |  ...|. ..||  .|||||.||   ..|
NFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPK--EYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase Gdt2.AA S_TKc 1290-1542 25 3e-60 207.4 SMART 1-231 (231) Show / Hide 
Range on Protein: 1290-1542
Range on HMM: 1-231/231
Sequence Identity: 25% (69 aa)

IIIKNYISEGTFGIVYRGIWRS--SPVAVKLLKNEYVDHDEIEKEISLLERLRHPNILLYVGRFIFSGIHGIVTDYCSK--GCLSKYIHENKYK-----I
  | . | .|.|| ||......    ||.| .|      . |..||..|.. .||||  . . |   .   .|..||.   | | .||......     .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

TIIQKIRILIDISKACAYLHRNGITHRDLKPENILITSLNPKSLVCAKVSDFGTSKETNERYNLQTRRGTVAYMSNEILSQGSYTK-STDIYSFGMLCYE
.  .  ...  | .| .|.|..|| ||||||||||...       . |..||| ...        |  ||  ||. |.|   .|.| . |..|.| . ||
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

LFSERIPYYSEPHWRIRELVLKNERPSLDQEIFKDTDISDIVTRCWSKNPSQRPTFDYLSK---------YL
... . |..   . .. ....             . .  |.. .|. |.|..|||   . .         ..
MLCGYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Gdt2.AA Pkinase 1290-1542 24 8.7e-55 193.12 Pfam 1-293 (293) Show / Hide 
Range on Protein: 1290-1542
Range on HMM: 1-293/293
Sequence Identity: 24% (74 aa)

IIIKNYISEGTFGIVYRGIWRSSP--VAVKLLKNEYVDHDEIEK-----EISLLERLRHPNILLYVGRFI-FSGIHGIVTDYCSKG----CLSKYIH-EN
. |.  | .|.|| ||........  |||| .| .  .... .      ||... ||.||||. . . |   . |. .|..|| .|     |. ||. ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIY-MVMEYCEGGLYVMDLFDYISTWR

KYKI--TIIQKIRILIDISKACAYLHRNGITHRDLKPENILIT-SLNPKSLVCAKVSDFGTSKE--TNERYNLQTRRGTVAYMSNEILS-QGSYTKSTDI
. ..  .  . ....  | .. .|.|..|| |||||||||||    ....  | |..||| .|   .     ..|. ||  ||. |..  .  |... |.
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA--CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

YSFGMLCYELFSERIPYYSE----PHWRIRELVLKNERPSLDQEIFKD---------------------TDISDIVTRCWSKNPSQRPTFDYLSKY--L
.|.| ..||... | |....    .  . .... .. .| |. .....                      .  |....|. |.|..|||.. . .   .
WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase Gdt2.AA TyrKc 1290-1542 23 1.4e-54 188.53 SMART 1-280 (280) Show / Hide 
Range on Protein: 1290-1542
Range on HMM: 1-280/280
Sequence Identity: 23% (68 aa)

IIIKNYISEGTFGIVYRGIWRSSPVAVKLLKNEYVDHDEIEKEISLLERL--RHPNILLYVGRFIFS-------GIHGIVTDYCSKGCLSKYIHENKYKI
|  .  . || ||.||.|.|.  .|||| ||..   . .. .|.... .|  .||||.  .|  . .       . . ||. |...|.| .|..... |.
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKL

TIIQKIRILIDISKACAYLHRNGITHRDLKPENILITSLNPKSLVCAKVSDFGTSKETNER--------YNLQ----TRR--GTVAYMSNEILSQGSYTK
.  ... . ..|.. ..|||.... ||||   |.|... .     ..|.|||| |..  .         |  .     ..    .  |. | .  | .| 
CMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

STDIYSFGMLCYELFSERIPYYSE------PHWRIRELVLKNERPSLDQEIF------KDTDISDIVTRCWSKNPSQRPTFDYLSKYL
 .|..||| ...|.|.   . |..      .  ...|.| . .|.   ...         ... .| ..||  .|..||||  . ...
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase Gdt2.AA MLK 1290-1542 24 5.9e-54 185.54 In-house 1-291 (291) Show / Hide 
Range on Protein: 1290-1542
Range on HMM: 1-291/291
Sequence Identity: 24% (73 aa)

IIIKNYISEGTFGIVYRGIWRSSP-----VAVKLLK-------NEYVDHDEIEKEISLLERLRHPN----ILLYVGRFIFSGIH-GIVTDYCSKGCLSKY
| .. .| .|.|| |..| ||        ||||  .        .|   ...|.|. .| .|.|||    |   .|  . .. | .||. ||..|.|. .
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

IHENK-------------YKITIIQKIRILIDISKACAYLHRNG---ITHRDLKPENILIT---SLNPKSLVCAKVSDFGTSKETNER-YNLQTRRGTVA
.|...               ..  .....  ..... .||| .    | |||||. ||||.   . . . ... |..|||||.. ...  |   ..||.|
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICH-DMHHGTL-KICDFGTSRDWHQMCTNMMSNAGTYA

YMSNEIL---SQGSYTKSTDIYSFGMLCYELFSERIPYY--SEPHWRIRELVLKNERPSLDQEIFKDTDISDIVTRCWSKNPSQRPTFDYLSKYL
.|. |..     . |... |..|.|.. .|... ..||    .|  .. . .....|| . ...  .  ..   ..||. .|..||.|..  ..|
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTC--PEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase Gdt2.AA TK 1290-1542 16 3e-51 169.65 In-house 1-486 (486) Show / Hide 
Range on Protein: 1290-1542
Range on HMM: 1-486/486
Sequence Identity: 16% (80 aa)

IIIKNYISEGTFG---IVYRGIWRS---------------------------SPVAVKLLKNEY-VDHDEIEK--------------EISLLERLR----
|.. . . || ||    ||.|.||.                            ||||| || .   . .| .               | . .. ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNILLYVG-------RFIFS-----GIHGIVTDYCSKGC----LSKYIHENKYK--------------------------------------------
 ||||.  .|       .. |.     .   ||. |...|.    | .| .... |                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------ITIIQKIRILIDISKACAYLHRN------GITHRDLKPENILITSLNP------KSLVCAKVSDFG---
                               .|  |.. .  .|.....|||..      .. ||||   |.|... |.       .  ..|..|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----TSKETN--ERYNLQTRRGT-------------------------VAYMSNEILSQGS---------YTKSTDIYSFGMLCYELFS-ERIPYYSEP
      ... .  . |  .. .||                         . .|. | |  .          .|  .|..||| |..|.|.  . ||| . 
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

HW----------RIRELVLK------------NERPSLDQ-EIFKD-------------TDISDIVTRCWSKNPSQRPTFDYLSKYL
.            . |.. .             .|  . | .   |             ... |. ..||...|..||||. | ..|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase Gdt2.AA LRRK 1290-1544 23 6e-50 172.25 In-house 1-351 (351) Show / Hide 
Range on Protein: 1290-1544
Range on HMM: 1-351/351
Sequence Identity: 23% (83 aa)

IIIKNYISEGTFG-IVYRGIWRS----------------------------SPVAVKLLKNE-----------------------------------YVD
..| . | .|.|| .|||..||.                            ..||.| .. .                                      
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

HDEIEKEISLLERLRHPNILLYVGRFIFSGIHGIVTDYCSKGCLSKYIHENK-YK-------ITIIQKIRILIDISKACAYLHRNG--ITHRDLKPENIL
. |  .|.... .|.||||.  .|  |   .  .|..| . | |....|..| ..       |.   |..| ..|.|. .|||..   | |||||..|||
FREFRHEVWIMSHLNHPNIVSLKGFCIHPLC--MVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNIL

ITSLN-------PKSLVCAKVSDFGTSK--ETNERYNLQTRRGTVAYMSNEILSQG---SYTKSTDIYSFGMLCYELFSERIPYYSE-P-------HWRI
. |..       |.  ||||..|||.|    .     . .  |.  .|. ||.  .   .||  .|.|||||. .|| . . ... | .       . .|
LWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQI

RELVLKNERPSLDQEIFKDT-----DISDIVTRCWSKNPSQRPTFDYLSKYLKH
......  ||.. |. .        . .|  . ||. .| .||.| .  | |. 
EDKIIEGLRPTIPQH-YCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase Gdt2.AA Dicty4 1290-1544 29 5.5e-47 154.82 In-house 1-277 (277) Show / Hide 
Range on Protein: 1290-1544
Range on HMM: 1-277/277
Sequence Identity: 29% (85 aa)

IIIKNYISEGTFGIVYRGIWRSSPVAVKLL--KNEYVDHDEIE---KEISLLERLRHPNILLYVGRFI----FSGIHGIVTDYCSKGCLSKYIHE-----
| | . | .| || ||.|.|| . ||||.|  .|. .| ....   ||....  .|||||.|  |  .     .|   ||| |..|| | . .|      
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

-NKYKIT--IIQK-IRILIDISKACAYLHR-N-GITHRDLKPENILITSLNPKSLVCAKVSDFGTSK----ETNERYNLQTRRGTVAYMSNEILSQGSYT
  . |.    | . .|. .|. .  ..||  |  | |||||. |.|.     |... .||.||| |.    ...   |. |  ||...|. |..   .|.
QQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVD----KNWR-VKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYN

KSTDIYSFGMLCYELFSERIPYY--SEPHWRIRELVLK-NERPSLDQEIFKDTDISDIVTRCWSKNPSQRPTFDYLSKY--LKH
 . | ||||.. .|..   .||     |   ....|    .||.. .    .. ... ...||...|..||.|   ...  | |
EKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWC--PPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase Gdt2.AA Pkinase_Tyr 1290-1542 26 1.1e-46 158.74 Pfam 1-270 (270) Show / Hide 
Range on Protein: 1290-1542
Range on HMM: 1-270/270
Sequence Identity: 26% (73 aa)

IIIKNYISEGTFGIVYRGIWR------SSPVAVKLLKNEYVDH----DEIEKEISLLERL-RHPNILLYVGRFI-FSGI--HGIVTDYCSKGCLSKYIHE
|..   . || || ||.|.|.        ||||| ||. . ..    ..  .|....  | .||||. ..|  .  ..   . ||. |. .|.| .| ..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

N---KYKITIIQKIRILIDISKACAYLHRNGITHRDLKPENILITSLNPKSLVCAKVSDFGTSKET--NERYNLQTRR---GTVAYMSNEILSQGSYTKS
.   | ..|. ... . ..|.|...||..... ||||   |.|.|.    .. ..|..||| ..     . | ...|      .  |. | .. | .|  
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE----NN-VVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTK

TDIYSFGMLCYELFS-ERIP-YYSEPHWRIRELV-LKNERPSLDQEIFKDTDISDIVTRCWSKNPSQRPTFDYLSKYL
.|..||| |..|.|.  ..| |.  .  .. |..  ...|  ...      .| |. ..|| ..|..|||| ..   |
SDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYR--MPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase Gdt2.AA STE 1290-1542 19 8e-46 158.56 In-house 1-359 (359) Show / Hide 
Range on Protein: 1290-1542
Range on HMM: 1-359/359
Sequence Identity: 19% (71 aa)

IIIKNYISEGTFGIVYRGIWRSSP-----------------VAVKLLKNEYVD------------------HDEIEKEISLLERLR--HPNILLYVGRFI
  .   | .|.|| ||... .  .                 .|.| .. |  .                  ...|.|||... ...  ||||  | | ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

FSG-------IHGIVTDYCSKGCLSKYIHEN-KYKITI------------IQKIRILIDISKA-CAYLHRNGITHRDLKPENILITSLNPKSLVCAKVSD
  |          |.  |.. |.|.. |... . . .              | ..|. .| |.  .|||...| |||.|| |||.          .| .|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----------VKLCD

FGTSKETNE-----------------RYNLQTRRGTVAYMSNEILSQ------GSYTKSTDIYSFGMLCYELFSERIPYYSEPHWRIRELVLKN------
||...  ..                   . .|  ||  .|. |...|      . |. . ||.|.| .. |.   . |.  ... |   . ..|      
FGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQ

---------ERPSLDQEIFKD-----------------TDISDIVTRCWSKNPSQRPTFDYLSK----YL
         . |.| ... ..                  .  | . .|  |.|..||| . | |     .
FEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase Gdt2.AA Dicty5 1290-1546 30 4.3e-42 142.66 In-house 1-260 (260) Show / Hide 
Range on Protein: 1290-1546
Range on HMM: 1-260/260
Sequence Identity: 30% (82 aa)

IIIKNYISEGTFGIVYRGIWRSSPVAVKLLKNEY---VDHDEIEKEISLLERLR--HPNILLYVGRFIFSGIH-GIVTDYCSKGCLSKYIHENKY----K
...  .|  |  | || || .   ||.| .  |     | .| ..|. ..      |||.  . |          .|| ||..| |. |  . .      
VSFHDWIASGASGRVYNGIYKGMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQP

ITIIQKIRILIDISKACAYLHRNGITHRDLKPENILITSLNPKSLVCAKVSDFGTSKETNERYNLQTRRGTVAYMSNEILSQGSYTKSTDIYSFGMLCYE
| . |.. . ||| ..  .||  .| |||||  |.|||    . .  .|. |||||     ||.  .  || ..|. |.     |.   |.||||   .|
IAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLIT----ENWK-IKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWE

LFSERIPYYSEPHWRIRELVLKNERPSLDQEIFKDTDISDIVTRCWSKNPSQRPTFDYLSKYLKHLL
.|    ||     | |  .| | ||| .   .   | || ..  ||   |..||.|    ||.. . 
MFTRKEPYDNINNWNIPVMVMKGERPTIPKDC--PTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase Gdt2.AA Ciliate-E2 1290-1536 19 7.8e-41 137.9 In-house 1-357 (365) Show / Hide 
Range on Protein: 1290-1536
Range on HMM: 1-357/365
Sequence Identity: 19% (73 aa)

IIIKNYISEGTFGIVYRGIWRSSP-------------------------VAVKLLKNEYVDHDEIEKEIS--------------LLERLRHPNILLYVGR
... . | .|.||.||..  .. .                         .|.| .|.  . . . |. |               .||.| ||||. ..  
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FI--FSGIHGIVTDYCSKGCLSKYIHENK----------YKITIIQKIRILIDISK---------------ACAYLHRNG-ITHRDLKPENILITSLNPK
|.        .|..||. | | .|| .||           ..|. . ..|   | .               |  ||| .. | |||.||||||.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

SLVCAKVSDFGTSKETNER----------YNLQTRR-----------------------GTVAYMSNEILSQGS---------YTKSTDIYSFGMLCYEL
     |..|||.||. ..           ....  .                       ||  ||. |||. ..         |... ||.|.|.. ||.
----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEM

FSERIPYYSEPHWRIRELVLKNERPSLDQE--------------IFKDTDIS--DIVTR----CWSKNPSQRPT-FD
 . . |.         .   |.   .....              ..|. . .  |.  .    .  |.|..|.| ..
LFGKPPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWE