Gene Gdt4 (Slime mold)

Gdt4

Species: Slime mold
Alias: DdisK214, Gdt4, DDB0220632
External Links: DictyBase Link ,
Annotation:

Classification

Group: TKL
Family: Gdt

Sequence

Name Sequence Type Origin Length Description Download
Gdt4.AA Protein None 1620 None Fasta, JSON
Gdt4.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of Gdt4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Gdt4.AA Gdt 1349-1600 51 4.6e-186 624.41 In-house 1-289 (289) Show / Hide 
Range on Protein: 1349-1600
Range on HMM: 1-289/289
Sequence Identity: 51% (149 aa)

IVLEKYLSEGSFGVVYSAIWRSSSVAVKLFKHHYS---------KDEIDKETSILSKIKHPNIVSFIGSLNFLNTYGIVIDYHPRGSLNYYTRNQN----
|....|.|.|.||.||..|||||.||||.|||||.         .|||..|..|||||||.|||||||...|.....||..|.|||||.||.....    
IDFKEYCSQGTFGMVYKGIWRSSQVAVKMFKHHYVNYTKTYSQSCDEIYREMDILSKIKHQNIVSFIGCVHFSSHHCIVTEYCPRGSLGYYIHQKKNQKK

------------------------IKLSMVQNIRISLDISRACSFLHKNGIIHRDLKPDNVLIVSFDPDSSICAKISDFGTCREINGKHELNSKAGTTRY
                        ||.||.|.|||..||...|.|||.||||||||||||.||.|....|..||||.||||..|||..|..|...||..|
SNTNTITNTITNTNTNTNTSTSTSIKMSMIQKIRIMIDIAKGCQFLHQNGIIHRDLKPDNILIFSTNENSEVCAKICDFGTSKEINEFHCKNTNCGTMNY

MSPEILEGLPYTYSTDVYSFAILFFELLSGRVPFREIPKREIPRFVRLGTRPRLDQDVFADNDISLILLACWNPNPRGRPTFDTLIDLL
||.||.||..|..|||||||.|||.|....|.||.||...|||.||..|.||.||||.|.||||..|...|||.||..|||||.....|
MSNEIFEGENYQKSTDVYSFGILFYEMMIERIPFHEICHWEIPNFVQDGWRPTLDQDIFDDNDIRNIIECCWNKNPHKRPTFDEISKHL
Kinase Gdt4.AA TKL 1355-1600 23 9.8e-86 291.14 In-house 1-364 (364) Show / Hide 
Range on Protein: 1355-1600
Range on HMM: 1-364/364
Sequence Identity: 23% (86 aa)

LSEGSFGVVYSAIWRS----------SSVAVKLFKHHYSK-----------------------------DEIDKETSILSKIKHPNIVSFIGSLNFLNT-
. .|.||.|| ..||             |||| || |...                             ... .|. ..|...|||||.|.|. .  .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YGIVIDYHPRGS-LNYYTRNQNIKLSMVQNIRISLDISRACSFLHKNG--------IIHRDLKPDNVLIVSF---------DPDSSIC
            ..|| .|.|.|| |.|..        . | .|..|||.|....|| ..        |||||||..|.|. .          .| . .|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

AKISDFGTCREINGKHE--------------------LNSKAGTTRYMSPEILEGL----------------PYTYSTDVYSFAILFFELLSGRVPFREI
.||.|||..|..... .                    .... ||.|.|.||.|.|                 .|. ..|||||.|...|.|....|....
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY

PKREIP---------RFVRL-GTRPRLD----------QDVFADNDISLILLACWNPNPRGRPTFDTLIDLL
| ...            | . | || ..          .   .. ... ..  ||...|. ||.|..... |
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase Gdt4.AA MLK 1349-1600 24 5.9e-63 215.47 In-house 1-291 (291) Show / Hide 
Range on Protein: 1349-1600
Range on HMM: 1-291/291
Sequence Identity: 24% (73 aa)

IVLEKYLSEGSFGVVYSAIWRSSS-----VAVKLFK--------HHYSKDEIDKETSILSKIKHPN----IVSFIGSLNFL-NTYGIVIDYHPRGSLNYY
| ..... .||||.|... ||        |||| ..           .......|  .|....|||    |. | |  .   . ..||  | . |||. .
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

TRNQN-------------IKLSMVQNIRISLDISRACSFLHKNG---IIHRDLKPDNVLIVS----FDPDSSICAKISDFGTCREINGKHE-LNSKAGTT
 ....             .  .. . ....|...|. ..||..    |||||||. |.||      .. .    .||.|||| |... ...   |.||| 
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGT---LKICDFGTSRDWHQMCTNMMSNAGTY

RYMSPEIL---EGLPYTYSTDVYSFAILFFELLSGRVPFR-EIP-KREIPRFVRLGTRPRLDQDVFADNDISLILLACWNPNPRGRPTFDTLIDLL
..|.||..   .. .|. . ||.|..... |.|...||.. ..   . .   .  |.|| . ..  ..  ..  .  |||..|. ||.|.  .  |
AWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPST--CPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase Gdt4.AA TKL-Unique 1350-1600 26 1.1e-59 204.6 In-house 1-290 (290) Show / Hide 
Range on Protein: 1350-1600
Range on HMM: 1-290/290
Sequence Identity: 26% (79 aa)

VLEKYLSEGSFGVVYSAIWRSSSVAVKLFK-----HHYSKDEIDKETSILSKIK-HPNIVSFIGSLN----FLNTYGIVIDYHPRGSLNYYTR-------
...| . ||..|.|| ..||...||.| |.     .  ...|  .| ....|.. ||||| ..|         . . || .| |.|||. .         
FWNK-IGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--NQNIKLSMVQNIRISLDISRACSFLHKNG--IIHRDLKPDNVLIVSFDPDSSICAKISDFGTCREINGKHELNSK----------AGTTRYMSPEILE
  |.|.||.| |.... .||.... .|| ..  |||||||. |.|.... .   . .||.|||...  .   . ...           |..|.|.||.|.
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLR

G--LPYTYSTDVYSFAILFFELLSGRV------PFREIPKREIPRFVRL---GTRPRLDQDVFADNDISLILLACWNPNPRGRPTFDTLIDLL
.    |. . |||||.|   |.... .      |....   ..   |.    . || . ..    .... .. .||...|  ||.||. |  |
MNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHC--PKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase Gdt4.AA Pkinase 1349-1600 24 4e-56 197.56 Pfam 1-293 (293) Show / Hide 
Range on Protein: 1349-1600
Range on HMM: 1-293/293
Sequence Identity: 24% (73 aa)

IVLEKYLSEGSFGVVYSAIWRSSS--VAVKLFKHHYSKDEIDK------ETSILSKIKHPNIVSFIGSL-NFLNTYGIVIDYHPRG----SLNYYTR-NQ
..... . .||||.|| .......  |||| .| .  |.. |.      | .|. ...||||| ....  .  . | .| .|.. |    .|  | .  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIY-MVMEYCEGGLYVMDLFDYISTWR

NIKL--SMVQNIRISLDISRACSFLHKNGIIHRDLKPDNVLIV-SFDPDSSICAKISDFGTCRE--INGKHELNSKAGTTRYMSPEILE-GLPYTYSTDV
. ..  |. . ... . | |.  ..|..|||||||||.|.||.   ..|.  | ||.||| ..   .  .. ... .|| .||.||..  | .|... |.
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA--CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

YSFAILFFELLSGRVPFREI----PKREIPRFVRLGTRPRLDQDVFAD---------------------NDISLILLACWNPNPRGRPTFDTLIDL--L
.|. ....|.|.|| ||..     . ..    ...  .|.|. | . .                      .   ..  |....|  |||.. .     .
WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase Gdt4.AA S_TKc 1349-1604 23 1.4e-55 191.93 SMART 1-231 (231) Show / Hide 
Range on Protein: 1349-1604
Range on HMM: 1-231/231
Sequence Identity: 23% (64 aa)

IVLEKYLSEGSFGVVYSAIWRS--SSVAVKLFKHHYSKDEIDKETSILSKIKHPNIVSFIGSLNFLNTYGIVIDYHPR--GSLNYYTRNQNIK-----LS
  . . . .|.||.|| .....    ||.|  |     . | .| .||.| .||||| ....    . . .| .| .   |.|  | .... .     ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

MVQNIRISLDISRACSFLHKNGIIHRDLKPDNVLIVSFDPDSSICAKISDFGTCREINGKHELNSKAGTTRYMSPEILEGLPYTY-STDVYSFAILFFEL
  .  ..   | .|  ..|..|||||||||.|.|. .       . ||.||| .|..      ..  ||  ||.||.|   .|.. . |..|. ....|.
E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LSGRVPFREIPKREIPRFVRLGTRPRLDQDVFADNDISLILLACWNPNPRGRPTFDTLID-----LLEKLL
|.|. ||.     .. .  ..            . .   ..  |.. .|. |||   .        .   .
LCGYPPFP-----QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Gdt4.AA TK 1349-1600 16 2.3e-50 166.63 In-house 1-486 (486) Show / Hide 
Range on Protein: 1349-1600
Range on HMM: 1-486/486
Sequence Identity: 16% (80 aa)

IVLEKYLSEGSFG---VVYSAIWRS---------------------------SSVAVKLFKHHYSKDEIDKET----------------SILSKIK----
|.|.| | || ||   .|| ..||.                             ||||  | . . .. ...                 ..... .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNIVSFIG--SLNFL----------NTYGIVIDYHPRGS----LNYYTRNQNIK--------------------------------------------
 |||||...|  . .              . ||  | | |.    |  | |.   |                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LSMVQNIRISLDISRACSFLHKN------GIIHRDLKPDNVLIVSFDP------DSSICAKISDFG---
                               |.| | . ....|......||..      ...||||   |.|. . ..      ..  ..||.|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----TCREINGKHELNSKAGTTR---------------------------YMSPEILEGLP---------YTYSTDVYSFAILFFELLS-GRVPFRE-I
      .|.|. ...  .| . ..                           .|.|| |..           .|  .||.|| .| .|... |..|. . .
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

PK---------REIPRFVRL------------GTRPRLDQDVFAD--------------NDISLILLACWNPNPRGRPTFDTLIDLL
.          .|. ...|             | | |. | . .                .. .... ||...|. ||||..| . |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase Gdt4.AA LRRK 1349-1602 23 1.8e-49 170.66 In-house 1-351 (351) Show / Hide 
Range on Protein: 1349-1602
Range on HMM: 1-351/351
Sequence Identity: 23% (84 aa)

IVLEKYLSEGSFG-VVYSAIWRS----------------------------SSVAVKLFKHH---------YSKD-------------------------
.. |. . .|.|| .|| |.||.                            ..||.| .. .          | .                         
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

--EIDKETSILSKIKHPNIVSFIGSLNFLNTYGIVIDYHPRGSLNYYTRNQN--------IKLSMVQNIRISLDISRACSFLHKNG--IIHRDLKPDNVL
  |  .| .|.|. .|||||| .|    .. . .| .| | |.|. . .|          ...|    ..|.|.|...  .||..   |||||||..|.|
FREFRHEVWIMSHLNHPNIVSLKGFC--IHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNIL

IVSFD-------PDSSICAKISDFGTCR--EINGKHELNSKAGTTRYMSPEILEG---LPYTYSTDVYSFAILFFELLSGR-VPFREIP-------KREI
. |..       |   .||||.|||. |   . ..  .. . |. ..|.|||. .     ||  .|.|||... .|||...  ||.|..         .|
LWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQI

PRFVRLGTRPRLDQDVFADN-----DISLILLACWNPNPRGRPTFDTLIDLLEK
   .  | || . |. .        . .  .  ||. .|. ||.| . .. |. 
EDKIIEGLRPTIPQH-YCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase Gdt4.AA TyrKc 1349-1600 28 2.7e-46 161.05 SMART 1-280 (280) Show / Hide 
Range on Protein: 1349-1600
Range on HMM: 1-280/280
Sequence Identity: 28% (81 aa)

IVLEKYLSEGSFGVVYSAIWRSSSVAVKLFKHHYSKDEIDKETSILSKI--KHPNIVSFIGSLNFL-------NTYGIVIDYHPRGSLNYYTRNQNIKLS
|.|.| | || ||.|| ..|.   ||||  |..  . .. .| .|..|.  .||||| ..|              . ||  | | |.|. | |.   ||.
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLC

MVQNIRISLDISRACSFLHKNGIIHRDLKPDNVLIVSFDPDSSICAKISDFGTCREINGK------HELNSKA---GTT-----RYMSPEILEGLPYTYS
| . . ....|.. ...||....|||||   |.|. .       ..|||||| .|.|  .      ..  .|.   |.      | |.|| .    .|  
MKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTK

TDVYSFAILFFELLS-GRVPFRE-----IPKREIPRFVRLGTRPRLDQD------VFADNDISLILLACWNPNPRGRPTFDTLIDLL
.||.|| .. .|... |  |  .     .. .|. ..|. | |..  ..      | .  ..  | . ||. .|  |||| ......
SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase Gdt4.AA Dicty5 1349-1604 29 1.3e-45 154.97 In-house 1-260 (260) Show / Hide 
Range on Protein: 1349-1604
Range on HMM: 1-260/260
Sequence Identity: 29% (78 aa)

IVLEKYLSEGSFGVVYSAIWRSSSVAVKLF---K-HHYSKDEIDKETSILSKIK--HPNIVSFIGSLNFLNTY-GIVIDYHPRGSLNYYTRNQNI----K
. . ..   |. | ||. | .   ||.| .      ..  .| ..|  |.| ..  |||.. . |       |  .|  |  .|||  | . |       
VSFHDWIASGASGRVYNGIYKGMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQP

LSMVQNIRISLDISRACSFLHKNGIIHRDLKPDNVLIVSFDPDSSICAKISDFGTCREINGKHELNSKAGTTRYMSPEILEGLPYTYSTDVYSFAILFFE
..  | . . .|| ..  .||  .|||||||  |.||          .|| |||| | .  . .     ||  .|..|.  | ||.   |||||.|  .|
IAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLI-----TENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWE

LLSGRVPFREIPKREIPRFVRLGTRPRLDQDVFADNDISLILLACWNPNPRGRPTFDTLIDLLEKLL
..    |. .| . .|| .|  | || .  |.     || .  .||   |. ||.|   .. .|.. 
MFTRKEPYDNINNWNIPVMVMKGERPTIPKDCPT--EISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase Gdt4.AA Dicty4 1349-1602 30 5.1e-45 148.19 In-house 1-277 (277) Show / Hide 
Range on Protein: 1349-1602
Range on HMM: 1-277/277
Sequence Identity: 30% (86 aa)

IVLEKYLSEGSFGVVYSAIWRSSSVAVKLF---KHHYSKDEID---KETSILSKIKHPNIVSFIGSLN----FLNTYGIVIDYHPRGSLNYYTRN-----
|. |. . .|||| || ..|| . ||||..   .   . ...    || .|..|| ||||. | |. .       .  ||  | |.|.|    ..     
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

-QNIKLS---MVQNIRISLDISRACSFLHK-N-GIIHRDLKPDNVLIVSFDPDSSICAKISDFGTCR----EINGKHELNSKAGTTRYMSPEILEGLPYT
 |.|||.   . . .|. .|. |    ||  |  |||||||..| |.     | .  .|..|||  .    ... |  . . .||. .|.||.. . ||.
QQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLV-----DKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYN

YSTDVYSFAILFFELLSGRVPFR-EIPKREIPRFVRL----GTRPRLDQDVFADNDISLILLACWNPNPRGRPTFDTLIDL--LEK
 . |||||.|. .|.| .  |.  ..  .... |||.    . || . ...  .. ..  .  ||...|  ||.|   |    || 
EKADVYSFGIVLWEILTRQEPYQKHH--MPYMQFVRAVCNKKLRPPIPDWC--PPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase Gdt4.AA CAMK 1354-1547 16 7.7e-45 141.97 In-house 1-336 (425) Show / Hide 
Range on Protein: 1354-1547
Range on HMM: 1-336/425
Sequence Identity: 16% (57 aa)

YLSEGSFGVVYSAIWRSSS--------------VAVKLFK------------------------------HHYSKDEIDKETSILSK-------IKHPNI
 | .||||.|. .| ...               ||.|  .                                ...... .| .|..|       ..||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VSFIGSLN------------FLNT--------YGIVI---DYHPRG----SLNYYTRNQ--------------NIKLSMVQNIRISLDISRACSFLHKNG
....                . ..        . .|    .| . |     |  | . .              . ...  .  |.   |  |  ..|...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIHRDLKPDNVLIVSFDPDSS------------ICAKISDFGTCREING------------------------KHELNSKAGTTRYMS-PEILEG-----
|.||||||.|.|... ..||.               ||.|||  .....                         . ..   ||  ||. ||.|.|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------LPYTYSTDVYSFAILFFELLSGRVPFRE
          .|....|. |  .. . .|.|. ||..
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYG
Kinase Gdt4.AA STE 1349-1597 18 1.1e-44 154.71 In-house 1-352 (359) Show / Hide 
Range on Protein: 1349-1597
Range on HMM: 1-352/359
Sequence Identity: 18% (66 aa)

IVLEKYLSEGSFGVVYSAIWRSSS-----------------VAVKLFKHHYS-------------------KDEIDKETSILSKIK--HPNIVSFIGSLN
  . . . .|.||.|| |. .  .                 .|.|  ..  .                   ...| || .|..| .  ||||| ..|.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

FL-------NTYGIVIDYHPRGSLN-YYTRNQNIKLSM------------VQNIRISLDISRA-CSFLHKNGIIHRDLKPDNVLIVSFDPDSSICAKISD
         ..  |.  | . |||   . ..  .. ..             | ..|  .| ..  ..||...|||||.||.|.|.          .|..|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----------VKLCD

FGTCREINGKH-----------------ELNSKAGTTRYMSPEILEG------LPYTYSTDVYSFAILFFELLSGRVPFRE-IPKREIPRFVRL------
||.|  .. ..                 . |. .||  .|.||....       .|... |..|. ..  |.. |..|. .  | | . .. .       
FGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQ

--------GTRPRLDQDVFAD-----------------NDISLILLACWNPNPRGRPTFDTLI
        |. |.| ...  .                  .    .  | . .|. ||| . |.
FEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLL
Kinase Gdt4.AA Pkinase_Tyr 1349-1600 26 1e-41 141.87 Pfam 1-270 (270) Show / Hide 
Range on Protein: 1349-1600
Range on HMM: 1-270/270
Sequence Identity: 26% (73 aa)

IVLEKYLSEGSFGVVYSAIWR------SSSVAVKLFKHHYSKDE-----IDKETSILSKI-KHPNIVSFIGSLN-FLNT--YGIVIDYHPRGSLNYYTRN
|.. | | ||.||.|| ..|.         ||||  |.......       .| .|.... .|||||...|          . ||  | | |.|  | |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

Q---NIKLSMVQNIRISLDISRACSFLHKNGIIHRDLKPDNVLIVSFDPDSSICAKISDFGTCREINGKHELNSKAGT-----TRYMSPEILEGLPYTYS
.   . .|.| . . ....|......|. ...|||||   |.|. .     . ..||.||| .| |  . .  .....      . |.|| .    .|  
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE-----NNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTK

TDVYSFAILFFELLS-GRVP-FREIPKREIPRFV-RLGTRPRLDQDVFADNDISLILLACWNPNPRGRPTFDTLIDLL
.||.|| .| .|... |. | . ...  |. ... . | |  ...   .  .|  ... ||...|  ||||  ..  |
SDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYR--MPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL