Gene Gdt8 (Slime mold)

Gdt8

Species: Slime mold
Alias: Gdt8, DdisK216, DDB0220636
External Links: DictyBase Link ,
Annotation:

Classification

Group: TKL
Family: Gdt

Sequence

Name Sequence Type Origin Length Description Download
Gdt8.AA Protein None 1326 None Fasta, JSON
Gdt8.kin_dom Protein Kinase Domain None 241 None Fasta, JSON

Protein domain

Protein domains of Gdt8.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Gdt8.AA Gdt 1052-1290 49 1.9e-170 572.55 In-house 15-289 (289) Show / Hide 
Range on Protein: 1052-1290
Range on HMM: 15-289/289
Sequence Identity: 49% (136 aa)

VFKGYYRDLAVAVKKFAISDN------SKSFEKIKNEVQILSKVNNINVVRYIGSAQNISHVCIVTEYAKEGSLGSLIHDSK------------------
|.||..|...||||.|.....      |.|...|..|..||||....|.|..||.....||.||||||...||||..||..|                  
VYKGIWRSSQVAVKMFKHHYVNYTKTYSQSCDEIYREMDILSKIKHQNIVSFIGCVHFSSHHCIVTEYCPRGSLGYYIHQKKNQKKSNTNTITNTITNTN

----------IKLSFIQKVKFMLDAAKGFTFLHASEIVHGDIKPDNLLVFS-KEISGVCVKICDFGNSEELGEKESKSKPDSTMNYLPNEVFDGEGYQKS
          ||.|.|||...|.|.|||..|||...|.|.|.||||.|.|| .|.|.||.||||||.|.|..|...|.....||||..||.|.||.||||
TNTNTSTSTSIKMSMIQKIRIMIDIAKGCQFLHQNGIIHRDLKPDNILIFSTNENSEVCAKICDFGTSKEINEFHCKNTNCGTMNYMSNEIFEGENYQKS

ADVYAFGVSLYEVMVEKIPFHEICYNDIPNRVQDGFRPTADLDTIDD-DIRKIIECCWIKEKSKRPSFSEISLHL
.|||.||...||.|.|.|||||||...|||.||||.|||.|.|..|| |||.||||||.|...|||.|.|||.||
TDVYSFGILFYEMMIERIPFHEICHWEIPNFVQDGWRPTLDQDIFDDNDIRNIIECCWNKNPHKRPTFDEISKHL
Kinase Gdt8.AA TKL 1052-1290 20 6.9e-71 241.82 In-house 9-364 (364) Show / Hide 
Range on Protein: 1052-1290
Range on HMM: 9-364/364
Sequence Identity: 20% (75 aa)

VFKGYYRD----------LAVAVKKFAISD--------------------------NSKSFEKIKNEVQILSKVNNINVVRYIGSAQNISH---------
|.||..|             |||||| . .                          .|. ......|. ..|. .  |.|...|.......         
VYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVG

----VCIVTEYAKEGSLGSLIHDSKIKLSFIQKVKFMLDAAKGFTFLHASE--------IVHGDIKPDNLLVFS----------KEISGVCVKICDFGNS
     |||.||.. ||| ...|       . |.....||.|.|  .||...        |.| |.|..|.||..          .... .|.|||||| |
PWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLS

EELGEKES--------------------KSKPDSTMNYLPNEVFDGE----------------GYQKSADVYAFGVSLYEVMVEKIPFHEICY-------
 .. ....                    ....  | .... ||..|.                 | ...|||.||. |.|..  ..|.... |       
RFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQD

---NDIPNRVQDGFRPTAD-----------LDTIDDDIRKIIECCWIKEKSKRPSFSEISLHL
    ..  ....| ||. .            ........|....||  . .|||||.||  .|
PFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase Gdt8.AA TKL-Unique 1052-1290 29 1.3e-54 187.8 In-house 13-290 (290) Show / Hide 
Range on Protein: 1052-1290
Range on HMM: 13-290/290
Sequence Identity: 29% (82 aa)

VFKGYYRDLAVAVKKFAI-SDNSKSFEK-IKNEVQILSKVN-NINVVRYIGSAQ----NISHVCIVTEYAKEGSLGSLIH---------DSKIKLSFIQK
|.|| .|   ||.|.|.. .| |.....  .||| ...| .  .|.|.|.|        ... |||.||  .||| ...|          ...||.. |.
VYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQR

VKFMLDAAKGFTFLHASE--IVHGDIKPDNLLVFSK-EISGVCVKICDFG----NSEELGEKES------KSKPDSTMNYLPNEVFDG--EGYQKSADVY
||. .|.|.|  .|| .|  | |.|.|. |.|| ..  |  . .||||||    || .. .. .      .. . .. .... ||. .  . |....|||
VKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVY

AFGVSLYEVMVEKI------PFHEICYNDIPNRVQD---GFRPTADL-DTIDDDIRKIIECCWIKEKSKRPSFSEISLHL
.||. |.|    ||      |....  . .   | .   ..||.  . . .  ..|..|. ||  . |.||||.||   |
SFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPP--IPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase Gdt8.AA MLK 1052-1290 25 4.6e-39 133.18 In-house 15-291 (291) Show / Hide 
Range on Protein: 1052-1290
Range on HMM: 15-291/291
Sequence Identity: 25% (70 aa)

VFKGYYRDLA-----VAVKKFA---ISDNSKS---FEKIKNEVQILSKVNNIN-----VVRYIGSAQNISHVCIVTEYAKEGSLGSLIHDSK--------
|.||..|        ||||...   . | |..    .... |. .|....  |     .. | ...|. .|.|||.||. .||| ...|. .        
VWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGARSKWMDANH

-----IKLSFIQKVKFMLDAAKGFTFLHASE---IVHGDIKPDNLLVFS--KEISGVCVKICDFGNSEELGEKES-KSKPDSTMNYLPNEVF---DGEGY
     .  .. ......|. |.|  .||. .   |.| |.|. |.|.    ... .  .|||||| | .. .... . .   |  .   ||.    .| |
NQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWMAPEVIQQFRCEKY

QKSADVYAFGVSLYEVMVEKIPFH-EIC-YNDIPNRVQDGFRPTADLDTIDDDIRKIIECCWIKEKSKRPSFSEISLHL
 ...||. .|| |.|..  ..|.. ..     .   .. | ||.    |... . | ...||  . .|||||..|  ||
SEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPI-PSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
S_TKc Gdt8.AA S_TKc 1036-1298 23 2.1e-38 134.81 SMART 1-231 (231) Show / Hide 
Range on Protein: 1036-1298
Range on HMM: 1-231/231
Sequence Identity: 23% (63 aa)

IKTEQLIASYLPSKVYVFKGYYRDLAVAVKKFAISDNSKSFEKIKNEVQILSKVNNINVVRYIGSAQNISHVCIVTEYAKE--GSLGSLIHDSKIK----
 .  ..| .   .|||  .    .  ||.|.          |.|..|.|||.| .  |.|..... |. .|...|.||.    |.| ..|.. . .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LSFIQKVKFMLDAAKGFTFLHASEIVHGDIKPDNLLVFSKEISGVCVKICDFGNSEELGEKESKSKPDSTMNYLPNEVFDGEGYQK-SADVYAFGVSLY
 ..  .  ..|   ...  ..|   |.| |.||.|.|. .      ..|||||| . .|      .    | .|.. ||.   || | ..|....|. ||
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

EVMVEKIPFHEICYNDIPNRVQDGFRPTADLDTIDDDIRKIIECCWIKEKSKRPSFSEISL-HLEIKFSKLL
| .. . ||.   .. . ...             ... . .|. |. |. .|||.  |.    ..||    .
EMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Gdt8.AA Pkinase 1052-1290 21 3.8e-34 121.83 Pfam 15-293 (293) Show / Hide 
Range on Protein: 1052-1290
Range on HMM: 15-293/293
Sequence Identity: 21% (61 aa)

VFKGYYRDLA--VAVKKFAISDNSKSFEKIK---NEVQILSKVNNINVVRYIGSAQNISHVCIVTEYAKEG----SLGSLIH-DSKIKL--SFIQKVKFM
|.|.. ..    ||||..  ...........   .|.||. ..|  |.||.... .. .|...|.||.  |    .| ..|. ... ..  |  .  ..|
VYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYM

LDAAKGFTFLHASEIVHGDIKPDNLLVFSKEISGVCVKICDFGNSEE--LGEKESKSKPDSTMNYLPNEVFD-GEGYQKSADVYAFGVSLYEVMVEKIPF
.  ..|  ..|.  |.| |.||.|.|. ..   . |||||||| ..   .  ..  . .  | .|.. ||   |..| ...|....|. |||..  . ||
YQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPF

HEI------CYNDIPNRVQDGFRPTADLDTID-------------------DDIRKIIECCWIKEKSKRPSFSEISLH--L
 .       . . . .|. ..  .     ...                   .. ...|..|. |  .|||.. .|  |  .
PGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase Gdt8.AA Dicty5 1036-1294 29 3.4e-33 111.61 In-house 1-260 (260) Show / Hide 
Range on Protein: 1036-1294
Range on HMM: 1-260/260
Sequence Identity: 29% (79 aa)

IKTEQLIASYLPSKVYVFKGYYRDLAVAVKKFAISD----NSKSFEKIKNEVQILSKVN--NINVVRYIGSAQNISHV-CIVTEYAKEGSLGSLIHDSKI
.   . |||    .||  .| |.   ||.| .        .  .|..   || |.| .     |..|. |  |       .|||| . ||| ..  | . 
VSFHDWIASGASGRVY--NGIYKGMDVAIKVYSQENCMCFDWNEFYR---EVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRK

----KLSFIQKVKFMLDAAKGFTFLHASEIVHGDIKPDNLLVFSKEISGVCVKICDFGNSEELGEKESKSKPDSTMNYLPNEVFDGEGYQKSADVYAFGV
     ... |.. . .|.|..  .||   |.| |.|  | |.         .|| ||| |     .        | ..   |.| | .|   .|||.||.
TTGQPIAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITEN----WKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGI

SLYEVMVEKIPFHEICYNDIPNRVQDGFRPT--ADLDTIDDDIRKIIECCWIKEKSKRPSFSEISLHLEIKF
 |.|..  | |. .|   .||. |. | |||  .|  |    | ..|. ||    ..|||| ||   .|   
VLWEMFTRKEPYDNINNWNIPVMVMKGERPTIPKDCPT---EISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase Gdt8.AA Ciliate-E2 1078-1271 18 1.2e-32 109.39 In-house 79-303 (365) Show / Hide 
Range on Protein: 1078-1271
Range on HMM: 79-303/365
Sequence Identity: 18% (50 aa)

KIKNEVQILSKVNNINVVRYIGSAQ--NISHVCIVTEYAKEGSLGSLIHDSKIK----------LSFIQKVKFMLDAAK---------------GFTFLH
|| || .||...|. |..... . |  . ... .|.||.. |.| ..| ..|.|          ..  .  ..|   ..               .. .||
KI-NEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLH

ASE-IVHGDIKPDNLLVFSKEISGVCVKICDFGNSEELGEKES---------KSKPDS------------------------TMNYLPNEVFDGEG----
    |.| ||||.|.|.         .||.|||.| .. ...          . .  .                        | .|.. |.. |..    
SKNNIIHRDIKPENILF---------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ

-----YQKSADVYAFGVSLYEVMVEKIPFHEICYNDIPNRVQDGFRPTADLDTIDDDIRKIIEC
     | ...|....|| ||| .  | ||                            ...|..|
QKQKGYDYKCDIWSLGVILYEMLFGKPPF----------------------------QQQIKQC
Kinase Gdt8.AA TK 1052-1290 12 1.3e-30 99.2 In-house 18-486 (486) Show / Hide 
Range on Protein: 1052-1290
Range on HMM: 18-486/486
Sequence Identity: 12% (60 aa)

VFKGYYRDL-----------------------------AVAVKKFAISDNSKSFEK-IKN----------EVQILSKVN-----NINVVRYIG-SAQNI-
|.|| .|..                             ||...|   ..... |.  . .          |...... .       |.|| .| . |.  
VYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVRLYGVCTQGEP

----------SHVCIVTEYAKEGS----LGSLIHDSKIK-------------------------------------------------------------
           ...||.||.. |.    | .  .... |                                                             
KPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKDL

--------------LSFIQKVKFMLDAAKGFTFLHAS------EIVHGDIKPDNLLVFSKEI-------SGVCVKICDFGNSEE----LGEKESKSKPDS
              |.  |.. .....|.|  .||.        .||.|.   | ||... .       .| ..||.||| | .    |  .  ...   
LQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYY

TMN-------------------------------YLPNEVFDGEG---------YQKSADVYAFGVSLYEVMV-EKIPFHEICYN----------DIPNR
...                               ... |....           .    ||..||| ..|..   . |...   |          .. ..
RKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEY

VQDG--------------FRPTADLDTID-------------DDIRKIIECCWIKEKSKRPSFSEISLHL
...|              .|. .  .  |             ...  .. .|| .. ..||.||..   |
LRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase Gdt8.AA Dicty4 1052-1182 34 7e-30 96.98 In-house 15-159 (277) Show / Hide 
Range on Protein: 1052-1182
Range on HMM: 15-159/277
Sequence Identity: 34% (52 aa)

VFKGYYRDLAVAVKKF---AISDNSKSFEKIKNEVQILSKVNNINVVRYIGSAQ----NISHVCIVTEYAKEGSLGSLIHD------SKIKLS--FIQK-
|.||  |  .|||||.    . . ..  .  ..|| |..|  . |..   |.      . . .||||||   |.| ||.||      ..|||.   | . 
VYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRA

VKFMLDAAKGFTFLHA--SEIVHGDIKPDNLLVFSKEISGVCVKICDFG
 . ..|||.| . ||.  . |.| |.|..|||| .|      ||.||||
MRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLV-DKNWR---VKVCDFG
Kinase Gdt8.AA STE 1052-1285 17 2.3e-28 97.31 In-house 15-350 (359) Show / Hide 
Range on Protein: 1052-1285
Range on HMM: 15-350/359
Sequence Identity: 17% (61 aa)

VFKGYYRD---LA--------------VAVKKFAISDNS----------------KSFEKIKNEVQILSKVN--NINVVRYIGSAQNI-------SHVCI
|.|.....   .               .|.|.  .....                . ...|..|..|..| |    |.|.|.|.  .        ....|
VYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWI

VTEYAKEGSLGSLIH---DSKIKLS----------FIQKVKFMLDAAKG-FTFLHASEIVHGDIKPDNLLVFSKEISGVCVKICDFGNSEELGE------
. ||   ||| ..|.     .  |.            |  ..  .  ||   .||   |.| ||||.| |.         ||.|||| .  | .      
CMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL---------VKLCDFGVCGQLTDSMANIQ

------------KESKSKPDSTMNYLPNEVFDG------EGYQKSADVYAFGVSLYEVMVEKIPFHEICYNDIPNRVQDGF-------------RPTADL
            .....   .   .   || ..       ||  ..|.. .|  . |    | |.|.  .     . ....              |   |
SNNIIDCIETMQQKRNTFVGTP--WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPL

-DTID-------------------DDIRKIIECCWIKEKSKRPSFSE
 |...                   .. .  |. | .|. .|||. |.
PDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ
Kinase Gdt8.AA LRRK 1052-1292 22 5.3e-28 96.13 In-house 16-351 (351) Show / Hide 
Range on Protein: 1052-1292
Range on HMM: 16-351/351
Sequence Identity: 22% (77 aa)

VFKGYYRD----------------------------LAVAVKKFAI-----------SDN----------------------SKSFEKIKNEVQILSKVN
|... .|.                              ||.||. .           |.|                      ...| .  .|| |.|. |
VYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRAFREFRHEVWIMSHLN

NINVVRYIGSAQNISHVCIVTEYAKEGSLGSLIHDSK--------IKLSFIQKVKFMLDAAKGFTFLHASE--IVHGDIKPDNLLVFSKEI--------S
  |.|  .|    |.. |.|.|||  |.| ...|..|        ...|   | | .|. |||  .|| .   |.| | |..| |..|            
HPNIVSLKGFC--IHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNA

GVCVKICDFGNSE--ELGEKESKSKPDSTMNYLPNEVFDGE---GYQKSADVYAFGVSLYEVMVEK-IPFHEIC-------YNDIPNRVQDGFRPTADLD
 ||.||.||| |       ..  ..   .  ..  |.  ..    |   .|.|.||. |.| .  . .|| |.         . | .....| |||   .
HVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQH

TIDD-----DIRKIIECCWIKEKSKRPSFSEISLHLEI
         .  . |. ||  .  |||.||.|   |. 
YCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase Gdt8.AA TyrKc 1052-1290 23 2.7e-25 91.26 SMART 15-280 (280) Show / Hide 
Range on Protein: 1052-1290
Range on HMM: 15-280/280
Sequence Identity: 23% (65 aa)

VFKGYYRDLAVAVKKFAISDNSKSFEKIKNEVQILSKV--NNINVVRYIGSAQNI-------SHVCIVTEYAKEGSLGSLIHDSKIKLSFIQKVKFMLDA
|.|| .. . ||||.   .      | . .| .|..|.  .. |.|| .| .            ..||.||.. |.| . ..... ||.  ....|....
VYKGTWK-IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQI

AKGFTFLHASEIVHGDIKPDNLLVFSKEISGVCVKICDFGNSEELGEK-------ESKSK-----PD--STMNYLPNEVF-DGEGYQKSADVYAFGVSLY
|.|  .||   ..| |.   | || ..     .|||.||| | .....       . ..|      .       .. |.. .|.   || ||..||| ..
ACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS-DVWSFGVCMW

EVM-VEKIPFHE-----ICYNDIPNRVQDGFRPTADLD-------TIDDDIRKIIECCWIKEKSKRPSFSEISLHL
|..   . |  .     .   .. ..|..|.|.    .       .  |.. .|...||  . ..||.||||   .
EIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase Gdt8.AA Pkinase_Tyr 1052-1182 26 1e-22 77.58 Pfam 15-156 (270) Show / Hide 
Range on Protein: 1052-1182
Range on HMM: 15-156/270
Sequence Identity: 26% (39 aa)

VFKGYYR------DLAVAVKKFAISDNSKS--FEKIKNEVQILSKV-NNINVVRYIGSAQ-----NISHVCIVTEYAKEGSLGSLIHDS---KIKLSFIQ
|.||...      .. ||||.   .  ..    |.  .|..|...  .. |.||..|        |  ...||.||.. |.| .  ..    | .|.  .
VYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN--QIYIVMEYMPHGDLLDYLRKHREDKQPLTMKD

KVKFMLDAAKGFTFLHASEIVHGDIKPDNLLVFSKEISGVCVKICDFG
.... .. |||  .|..  ..| |.   | || .   .. .|||||||
LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE---NN-VVKICDFG
Kinase Gdt8.AA Pkinase_Tyr 1218-1290 27 1.6e-08 29.48 Pfam 196-270 (270) Show / Hide 
Range on Protein: 1218-1290
Range on HMM: 196-270/270
Sequence Identity: 27% (21 aa)

DVYAFGVSLYEVMV-EKIP-FHEICYNDIPNRV-QDGFRPTADLDTIDDDIRKIIECCWIKEKSKRPSFSEISLHL
||..||| ..|..   ..| . ..  ... ... .|| |  .  .   |.| ...  || .. ..||.||||  .|
DVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPC-PENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase Gdt8.AA Dicty4 1259-1292 33 0.000401 9.84 In-house 242-277 (277) Show / Hide 
Range on Protein: 1259-1292
Range on HMM: 242-277/277
Sequence Identity: 33% (12 aa)

DTIDDDIRKIIECCWIKEKSKRPSFSEISLH--LEI
|  .. ... |. || .. ..||||.||.    || 
DWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase Gdt8.AA Dicty4 1206-1239 34 0.031306 3.44 In-house 187-221 (277) Show / Hide 
Range on Protein: 1206-1239
Range on HMM: 187-221/277
Sequence Identity: 34% (12 aa)

EVFDGEGYQKSADVYAFGVSLYEVMVEKIPFH-EI
||  ...|  .|||| ||  |.|    ..|.  ..
EVMMHQPYNEKADVYSFGIVLWEILTRQEPYQKHH