Gene rk2 (Slime mold)

rk2

Species: Slime mold
Alias: DdisK199, DDB0229954, rk2
External Links: DictyBase Link ,
Annotation:

Classification

Group: TKL
Family: Dicty4
Subfamily: DRK

Sequence

Name Sequence Type Origin Length Description Download
rk2.AA Protein None 690 None Fasta, JSON
rk2.kin_dom Protein Kinase Domain None 250 None Fasta, JSON

Protein domain

Protein domains of rk2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase rk2.AA DRK 391-643 70 3.7e-225 754.31 In-house 1-258 (258) Show / Hide 
Range on Protein: 391-643
Range on HMM: 1-258/258
Sequence Identity: 70% (181 aa)

IKIGVRIGKGNFGEVYLGTWRGSQVAVKKLPAHNIN-ENILKEFHREINLMKNLRHPNVIQFLGSCLISPDICICTEYMPRGSLYSILHNEKIKISWSLV
||||.|||.||.|||..|||||.|||||.|..|||| ||.|.|||||||||..|||||..||.|.|...||||||.|||||||||.|||.|.|...|.|.
IKIGNRIGRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLM

KRMMIDAAKGIIYLHGSTPVILHRDLKSHNLLVDENWKVKVADFGLST----IEQQGATMTACGTPCWTSPEVLRSQRYTEKADVYSFGIILWECATRQD
|.||.|.|||.||||...|.|.|||||||||||||.|.||||||||||    ..|....||.|||||||.|||||.||||||||||||.|.||||.||||
KQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECVTRQD

PYFGIPPFQVIFAVGREGMRPPTPKYGPPKYIQLLKDCLNENPSQRPTMEQCLEILES
||||.|.|||.|.|||.|||||.|...|||||||..||.||.|..||.|..|||.||.
PYFGMPTFQVVFSVGRHGMRPPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase rk2.AA Dicty4 391-643 51 7.6e-189 633.67 In-house 1-277 (277) Show / Hide 
Range on Protein: 391-643
Range on HMM: 1-277/277
Sequence Identity: 51% (142 aa)

IKIGVRIGKGNFGEVYLGTWRGSQVAVKKLPAHNIN--ENILKEFHREINLMKNLRHPNVIQFLGSCL----ISPDICICTEYMPRGSLYSILHN-----
|.|..|||||.|||||.|||||..||||||..||.|  ||.|.||..|...|...||||...|.|.|.    .....||.|||||.|.|||.||.     
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

-EKIKISWSLVKR---MMIDAAKGIIYLHGSTPVILHRDLKSHNLLVDENWKVKVADFGLST----IEQQGA-TMTACGTPCWTSPEVLRSQRYTEKADV
 ..||..|.|.||   |..|||.|...||...|||.||||||||||||.||.|||.|||||.    .|.... .|||||||||..|||...|.|.|||||
QQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADV

YSFGIILWECATRQDPYF--GIPPFQVIFAVGREGMRPPTPKYGPPKYIQLLKDCLNENPSQRPTMEQCLEI--LES
|||||.|||..|||.||.  ..|..|...||.....||| |...||....|...|....|..||..|.....  ||.
YSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase rk2.AA TKL 397-641 32 1.1e-114 387.34 In-house 1-364 (364) Show / Hide 
Range on Protein: 397-641
Range on HMM: 1-364/364
Sequence Identity: 32% (122 aa)

IGKGNFGEVYLGTWRG----------SQVAVKKLPAHNINENIL-------------------------KEFHREINLMKNLRHPNVIQFLGSCLISPD-
||.| ||||| |.|||            |||||.. || .|. .                         ... .||..|..|||||..||.|.|. .|. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------ICICTEYMPRGSLYSILHNEKIKISWSLVKRMMIDAAKGIIYLHGST------PVILHRDLKSHNLLVDENWK--------------V
            .|| .||.|.|||...||       |..  |...|.|.|. ||| ..      | |.||||||.|.||||||.              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KVADFGLSTIEQQG---------------------ATMTACGTPCWTSPEVLRSQ----------------RYTEKADVYSFGIILWECATRQDPYFGIP
|..|||||.  .|                      .||| ||||.| .||||| |                 |.||.|||||||.|||..||. ||...|
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

PFQVI---------FAVGREGMRPPTP------------KYGPPKYIQLLKDCLNENPSQRPTMEQCLEIL
....|           |. .|.||| |            .. || ...|..|| ...|..||.....|..|
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase rk2.AA TKL-Unique 393-641 38 4.2e-101 342.18 In-house 1-290 (290) Show / Hide 
Range on Protein: 393-641
Range on HMM: 1-290/290
Sequence Identity: 38% (112 aa)

IGVRIGKGNFGEVYLGTWRGSQVAVKKLPA-HNINENILKEFHREINLMKNLR-HPNVIQFLGSCL----ISPDICICTEYMPRGSLYSILH--------
..  || | .|.|| |.|||..||.|..     ..  ...||..|.|.||.|. |||. .. | |       |. || .||.|.||||. ||        
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

-NEKIKISWSLVKRMMIDAAKGIIYLHGSTPVILHRDLKSHNLLVDEN-----WKVKVADFGLSTIEQQGATMTAC-----------GTPCWTSPEVLRS
 |...|...... .| ||.|.| .||| . | |.|||||| |.|||.|     |..|..|||||..  .  .||.            |.. | .|||||.
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--QRYTEKADVYSFGIILWECATRQD------PYFGIPPFQVIFAVGR--EGMRPPTPKYGPPKYIQLLKDCLNENPSQRPTMEQCLEIL
    |.||.|||||||.|||.|||.       || |. . |.. .|    |. ||| |   |. |  |...| . .|||||. .. .. |
NFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase rk2.AA MLK 391-641 34 3.3e-91 309.32 In-house 1-291 (291) Show / Hide 
Range on Protein: 391-641
Range on HMM: 1-291/291
Sequence Identity: 34% (101 aa)

IKIGVRIGKGNFGEVYLGTWRGSQ-----VAVKKLPAHN----INENILKEFHREINLMKNLRHPN----VIQFLGSCLISPD-ICICTEYMPRGSLYSI
|..   ||.| ||.|..|.||.       ||||.  |      . . . ..| .|... . |.|||    .|||.| || .|   || .||.. ||||..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LHNEK-------------IKISWSLVKRMMIDAAKGIIYLHGSTPV-ILHRDLKSHNLLVDE------NWKVKVADFGLST-IEQQGATMTA-CGTPCWT
||...             . .. ... . . . |.|. |||   |. | ||||||||.|.||      . ..|..|||.|. . | ...|.  .||. | 
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWM

SPEVL---RSQRYTEKADVYSFGIILWECATRQDPYF-GIPPFQVIFAVGREGMRPPTPKYGPPKYIQLLKDCLNENPSQRPTMEQCLEIL
.|||.   |...|.||.||.|.|..|||  ||. ||  .. |..... |. .| ||| |.  |.   .|.|.| |..|..||.. |....|
APEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase rk2.AA LRRK 391-643 29 6.2e-83 281.83 In-house 1-351 (351) Show / Hide 
Range on Protein: 391-643
Range on HMM: 1-351/351
Sequence Identity: 29% (105 aa)

IKIGVRIGKGNFG-EVYLGTWRG----------------------------SQVAVKKLPAH---------NINE-----------------------NI
.||.  ||.| || .|| ..|||                            . ||.||.  .         | |                        ..
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

LKEFHREINLMKNLRHPNVIQFLGSCLISPDICICTEYMPRGSLYSILHNEK--------IKISWSLVKRMMIDAAKGIIYLHGSTPVILHRDLKSHNLL
. ||..|. .| .|.|||... .| | |.| .|. .||.| |.||. |||.|        ..|||.|. . ... |||. ||| ..| |.||||||.| |
FREFRHEVWIMSHLNHPNIVSLKGFC-IHP-LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNIL

V---D---------ENWKVKVADFGLST---IEQQGATMTACGTPCWTSPEVLRSQ---RYTEKADVYSFGIILWECATRQ-DPYFGIP-P--FQVIFAV
.   .         .. ..|.||||.|.   . . |....  |.| | .||..|      ||||.|.||||.||||. ||| .|. ... .  .| .  .
LWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQI

GR---EGMRPPTP---KYG---PPKYIQLLKDCLNENPSQRPTMEQCLEILES
     || ||. |    ..   .. | .|...| ...| .||...| ...|..
EDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase rk2.AA Shk 391-646 40 3.5e-78 266.06 In-house 1-269 (269) Show / Hide 
Range on Protein: 391-646
Range on HMM: 1-269/269
Sequence Identity: 40% (110 aa)

IKIGVRIGKGNFGEVYLGTWRGSQVAVKKLPAHNINENILKEFHREINLMKNLRHPNVIQFLGSCL-ISPDICICTEYMPRGSLYSILHNEKIKISWSLV
|     .| | || || |. ||  ||||..   |  || ...|  |  .|. ..|||.. |.| |  .. .. |.|| ||.|.| . ||. ..|   .| 
INREDFLGQGSFGKVYKGRCRGKEVAVKVMHKQNFDENTMTSFRKEVHIMSKIFHPNICLFMGACTSQPGKCMIVTELMPKGNLEKLLHDQMVKKPFILY

KR-MMI--DAAKGIIYLHGSTPVILHRDLKSHNLLVDENWKVKVADFGLSTIEQQGA-----TMTACGTPCWTSPEVLRSQRYTEKADVYSFGIILWECA
|| | .  ||| |.  |||| ..|.|||||. |||||.|| |||.|||.| . ...         | ||| |  |||.  . | |||||||||||||| .
KRAMRMCRDAALGMNWLHGSNCNIIHRDLKTANLLVDQNWRVKVCDFGFSQYMKKHEMLKDKQKGAKGTPLWMAPEVMMNHPYNEKADVYSFGIILWEIL

TRQDPYF----GIPPFQVIFAVGREGMRPPTPKYGPPKYIQLLKDCLNENPSQRPTMEQCLEI--LESIET
|.| ||      ...|    |.  .  ||| | . |.   .|.  |   ||..||  .  .    |. | .
TCQEPYPKHHSEYDKF--YEAICNKKERPPIPDDCPKSLKHLIQKCWDHNPQRRPSFNEIIQRRILNHILI
Kinase rk2.AA TKL-ciliate2 391-642 38 1.3e-75 251.85 In-house 1-273 (273) Show / Hide 
Range on Protein: 391-642
Range on HMM: 1-273/273
Sequence Identity: 38% (104 aa)

IKIGVRIGKGNFGEVYLGTWRGSQVAVKKLPAHNINENILKEFHREINLMKNLRHPNVIQFLGSCLISPDICICTEYMPRGSLYSILHNEKIKISWSLVK
..|  .|  | .| .|   ||   |||||      |.  ...|  | . |  |||||.. ||| |  .|  ||  ||  ||||.|.| |. ....|   .
LEIQNKITEGGYGIIYKAKWREIVVAVKKFKMDHDNQQQIRDFVNECHAMEALRHPNIVMFLGACTKIPNFCIIMEYCQRGSLWSLLQNQDVRLTWEDRR

RMMIDAAKGIIYLHGSTPVILHRDLK--------------------SHNLLVDENWKVKVADFGLSTIEQQGATMTA-CGTPCWTSPEVLRSQRYTEKAD
|. .|.|.|. ||| | | |.|||||                    | |.|||.| . |..|||   .  |   ||.  ||  |  |||...  ||||||
RIALDIARGVHYLHSSNPPIIHRDLKRQIKHKEKNLINIITLIKINSLNVLVDDNFRCKLTDFGWTRVKPQDNYMTNKIGTYQWMAPEVIKAFYYTEKAD

VYSFGIILWECATRQDPYFGIPPFQVIFAVGREGMRPPTPKYGPPKYIQLLKDCLNENPSQRPTMEQCLEILE
|.|..||||| | |  || ..    |   | .. .||  ||  ||.. .|.. | ..|   ||.... .  ||
VFSYSIILWEIASREPPYRNKKGDVVAEKVMCNNLRPTIPKNCPPQFADLMQRCWDNNQNLRPSFNEIIKELE
Kinase rk2.AA Dicty4-Unclassified 391-641 34 8.9e-75 254.74 In-house 1-263 (263) Show / Hide 
Range on Protein: 391-641
Range on HMM: 1-263/263
Sequence Identity: 34% (92 aa)

IKIGVRIGKGNFGEVYLGTWRGSQVAVKKL--PAHNINENILKEFHREINLMKNLRHPNVIQFLGSCLISP-----DICICTEYMPRGSLYSILH-----
|.|   |||| | .|. | |.|  |||||.        | ....| .|. ..  . ||| ..  | | | |      .|| .| |..| |  . |     
IQIDQFIGKGHFSKVHKGNWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYC-INPRSHKSTMCIVMEFMHKGNLFEVIHSKPSE

-NEKIKISWSLVKRMMIDAAKGIIYLHGSTPVILHRDLKSHNLLVDENWKVKVADFGLSTIEQQGATMTACG-TPCWTSPEVLRSQRYTEKADVYSFGII
 .  ||    |. .. .| |.|. .||  |  . |||.|| |.|.| .  .|.||||.|       .||. . || |.|||.|.   |. |.||||....
QQQPIKLDDTLIIKYAFDIAQGMQHLH--TRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMM

LWECATRQDPYFGIP-PFQVIFAVGREGMRPPTPKYGPPKYIQLLKDCLNENPSQRPTMEQCLEIL
|.| ||   || .|. .  .   |   ..||  |   .. . .| |.|. . |  ||||.|  . |
LYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase rk2.AA Pkinase_Tyr 391-641 33 6e-74 251.07 Pfam 1-270 (270) Show / Hide 
Range on Protein: 391-641
Range on HMM: 1-270/270
Sequence Identity: 33% (92 aa)

IKIGVRIGKGNFGEVYLGTWR------GSQVAVKKLPAHNINEN-ILKEFHREINLMKNL-RHPNVIQFLGSCL-ISPD--ICICTEYMPRGSLYSILHN
|..|  .|.|.|||||.|||.      . .||||.|. .   |. ....| ||...||.| .|||.....| |.  .    |.| .|||| |.|.. |..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

E---KIKISWSLVKRMMIDAAKGIIYLHGSTPVILHRDLKSHNLLVDENWKVKVADFGLSTIEQQGATM-TACG----TPCWTSPEVLRSQRYTEKADVY
    | ... .    | .. |||  ||.     . ||||   | ||.|| .||..||||.   .   .  .. |       |..||...  ..|.| ||.
HREDKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SFGIILWECAT-RQDP-YFGIPPFQVIFAVGREGMRPPTPKYGPPKYIQLLKDCLNENPSQRPTMEQCLEIL
|||. .||  |  . | | |.....|. .....| | | |.. |..  .|.|.| ...|..|||.....|.|
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase rk2.AA Pkinase 391-641 27 1e-71 249.36 Pfam 1-293 (293) Show / Hide 
Range on Protein: 391-641
Range on HMM: 1-293/293
Sequence Identity: 27% (82 aa)

IKIGVRIGKGNFGEVYLGTWRGSQ--VAVKKLPAHNINENILKEFHR--EINLMKNLRHPNVIQFLGSCLISPDICICTEYMPRG----SLYSILH-NEK
..|| .||.|.||.||.....|..  ||||... ...... ...  |  || .||.|.|||........  ...|....||.. |    .|.....  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

IKI--SWSLVKRMMIDAAKGIIYLHGSTPVILHRDLKSHNLLVDENWKV----KVADFGLST---IEQQGATMTACGTPCWTSPEVLR-SQRYTEKADVY
 ..  |.  .|..|   ..|. |.|     |.|||||. |.|.|.|  .    |..||||.    .  .. ..| |||| . .|||.| .| |. |.|..
GCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SFGIILWECATRQDPYFGI------PPFQVIFAVGREGMRPPTPKYGP-------------------PKYIQLLKDCLNENPSQRPTMEQCLEI--L
|.|.||.| .... |. |        . |.|. ...   . . |.  .                   .  ....|.||. .|..||| ||.|.   .
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase rk2.AA TyrKc 391-641 32 2e-71 244.53 SMART 1-280 (280) Show / Hide 
Range on Protein: 391-641
Range on HMM: 1-280/280
Sequence Identity: 32% (93 aa)

IKIGVRIGKGNFGEVYLGTWRGSQVAVKKLPAHNINENILKEFHREINLMKNL--RHPNVIQFLGSCLIS-------PDICICTEYMPRGSLYSILHNEK
|. |  .| |.|||||.|||.  |||||.| ..      ...|.||...|..|  .|||.....| |. .       . ..| .|||| |.| . |.. .
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

IKISWSLVKRMMIDAAKGIIYLHGSTPVILHRDLKSHNLLVDENWKVKVADFGLSTIEQQG-------ATMTA----CGT-PC---WTSPEVLRSQRYTE
 |....    .....|.|  |||     . ||||   | ||.||  ||..|||||     .        . ..    .|  .    |..||...  ..|.
PKLCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KADVYSFGIILWECATR-QDPYFG-----IPPFQVIFAVGREGMRPPTPKY--------GPPKYIQLLKDCLNENPSQRPTMEQCLEIL
| ||.|||. .||  |. | || |     .....||  | ..|.|.| |..         |..  |. |.| .|.|..|||.... |..
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYV-KQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase rk2.AA CZAK 391-641 37 1.1e-68 234.55 In-house 1-279 (279) Show / Hide 
Range on Protein: 391-641
Range on HMM: 1-279/279
Sequence Identity: 37% (106 aa)

IKIGVRIGKGNFGEVYLGTWRGSQVAVKKLPA---HNINEN-ILKEFHREINLMKNLRHPNVIQFLGSCLISP--DICICTEYMPRGSLYSILHNEKIKI
 |.|  ||.| ||||| . |||  ||.|..      |  ||  .  | .|.  |  |.|||..|||| |      . || .|.|  |||   |      .
LKFGQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHYFYH

SW--SLVKRMMIDAAKGIIYLHG-STP-VILHRDLKSHNLLVDENWK-------------VKVADFGLS-TIEQQGATMTAC-GTPCWTSPEVLRSQRYT
    .|   | || |.|  |||.  .|  |||||| | | | |..                |..|||||     |.  ||.  |  ||  ||.     ||
KQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFKGENYT

EKADVYSFGIILWECATRQDPYFGIPPFQVIFAVGREGMRPPTPKYGPPKYI---QLLKDCLNENPSQRPTMEQCLEIL
||.||||||.|||.  |  .|| .. |    .    |  ||| |   .|.      |.  | | ||. ||.  | |..|
EKVDVYSFGMILWCIITCDQPYQNMQPMKMAHLAAYENYRPPMPQPMDPMWKNLGELIEMCWNKNPDERPSFKQILQHL
Kinase rk2.AA S_TKc 391-644 25 2e-67 231.25 SMART 1-231 (231) Show / Hide 
Range on Protein: 391-644
Range on HMM: 1-231/231
Sequence Identity: 25% (69 aa)

IKIGVRIGKGNFGEVYLGTWRG--SQVAVKKLPAHNINENILKEFHREINLMKNLRHPNVIQFLGSCLISPDICICTEYMPR--GSLYSILHNEKIK---
 .|.  |||| ||.||......   .||.|...         . . |||...|. .|||........    ......||..   |.|...... . .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--ISWSLVKRMMIDAAKGIIYLHGSTPVILHRDLKSHNLLVDENWKVKVADFGLSTIEQQGATMTACGTPCWTSPEVLRSQRYTE-KADVYSFGIILWEC
  ..   ....|   .... |.|     |.|||||  |.|.||   .|..||||...      .| |||| . .||||    |.  |.|..|.|.||.|.
FPFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

ATRQDPYFGIPPFQVIFAVGREGMRPPTPKYGPPKYIQLLKDCLNENPSQRPTMEQCLE------ILESI
.... |.      |..| . .           .|  ..... ||. .|..|||  ..|.      . . .
LCGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF