Gene 6347 (Tetrahymena)

6347

Species: Tetrahymena
Alias: 6347, 3722.m00005, PreTt06347, TTHERM_00525100, 66.m00146, 362
External Links: Tetrahymena Genome Database (TGD)
Annotation: Secondary Group: Other, Secondary Family: ULK,

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
6347.AA Protein None 793 None Fasta, JSON
6347.kin_dom Protein Kinase Domain None 266 None Fasta, JSON
6347.kin_dom2 Protein Kinase Domain None 251 None Fasta, JSON
6347.NA RNA None 2382 None Fasta, JSON

Protein domain

Protein domains of 6347.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 6347.AA ULK 17-282 36 1.1e-117 397.32 In-house 1-324 (324) Show / Hide 
Range on Protein: 17-282
Range on HMM: 1-324/324
Sequence Identity: 36% (121 aa)

YEVIKELGRGSFG-VVYLG--IKQ---GEELAIKTIKKDKIQRSQKLTE------LLDSEKQLLSTIK---SNH--ITKLFEFFETD--KNCFLAMEYCN
|.....|| |||| .|| |  .|.   ..  |.| | |.|.. .... |      ||..| |.. ..|   ...  | ||...|||.  .|... |||||
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGTLEKYIQQKKL---------ISEKEAKGYLIQLLSGFKDLHSHLVIHRDIKLENIMRHFPNGQTGNDTYDNK---NVVLKIADLGLAKE----MKDEM
||.||.||...|          .||.||.....|...|||.||.| .||||||..||. | ....| ...   |   |.|||||| |.||     .....
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKT-DSK---KVHPNGVLKIADFGFAKHVDNNNMEQQ

IAHTYA------GTVLTMAPEILK----QKSYG-FEVDVYSLGVILYYMVQGKYPFYEN-NDTK-----LLQK-------IKEQNIQFK---DENPVSLE
. .|.       || |.|||.||.    || |. ...|..|||.|.|.|. |||||... ||..     |...       || |.|||.   .....| |
MCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPE

FQDLIKQMLKYNKKQRITWSGIINHKAI
..|||..||.|. |.||.|  |.||. .
CKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 6347.AA ULK 17-282 35 2.4e-115 389.53 In-house 1-329 (329) Show / Hide 
Range on Protein: 17-282
Range on HMM: 1-329/329
Sequence Identity: 35% (119 aa)

YEVIKELGRGSFGVVYLGI---KQ---GEELAIKTIKKDKIQRSQKLTE------LLDSEKQLLSTIK----SNH----ITKLFEFFETD--KNCFLAME
|.....|| ||||.|| |.   ..   .|  |.| | |.|....... |      ||..| ... ..|    ...    | ||...|||.  .|... ||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCNGGTLEKYIQQKKL----------ISEKEAKGYLIQLLSGFKDLHSHLVIHRDIKLENIMRHFPNGQTGNDTYDNK---NVVLKIADLGLAKEMKDE-
|||||.||.||...|           .||.||. ...|.|.|||.||.| .||||||..||. | ....| ...   |   |.|||||| |.|| . .. 
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKT-DSK---KVHPNGVLKIADFGFAKHVDNDN

---MIAHTYA------GTVLTMAPEILK----QKSYG-FEVDVYSLGVILYYMVQGKYPFYEN-NDTK------LLQK-------IKEQNIQFK---DEN
    ...|.       || |.|||.||.    || |. ...|..|||.|.|.|. ||.|||.. ||..      |...       || |..||.   ...
MEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDP

PVSLEFQDLIKQMLKYNKKQRITWSGIINHKAI
..| |..|||..||.|. |.||.|  ..||. .
QISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 6347.AA Ciliate-E2 17-282 26 2.4e-88 299.8 In-house 1-365 (365) Show / Hide 
Range on Protein: 17-282
Range on HMM: 1-365/365
Sequence Identity: 26% (104 aa)

YEVIKELGRGSFGVVYLG--IKQGE-----------------------ELAIKTI-KKDKIQRSQKLTEL---------LDSEKQLLSTIKSNHITKLFE
|..|| .|.|.||.||..  .|...                       . |.|.. |....| .|.. ..         .  ||..|.......| |..|
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKI-NEKNILEQLNHPNIIKMYE

FFE--TDKNCFLAMEYCNGGTLEKYIQQKKLIS-----------EKEAKGYLIQLLS---------------GFKDLHSHL-VIHRDIKLENIMRHFPNG
.|.  .|.|..| ||||.||.|..||...|. .           |||.| .  |.|.               ... |||   .||||||.|||.      
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

QTGNDTYDNKNVVLKIADLGLAKEMKDE--------------------------------MIAHTYAGTVLTMAPEILKQKS---------YGFEVDVYS
             .||.|.||.|. .|.                                ....|..||   ||||||. |.         |....|..|
-------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWS

LGVILYYMVQGKYPFYENNDTKLLQKIKEQNIQFK----------------DENPVSLEFQDLIKQ----MLKYNKKQRIT-WSGIINHKAI
||||||.|. ||.||        .|.||...|.|                 . . .|.| .||||.    ||... ..||| |. |.||. .
LGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 6347.AA S_TKc 17-282 28 3.8e-83 283.47 SMART 1-231 (231) Show / Hide 
Range on Protein: 17-282
Range on HMM: 1-231/231
Sequence Identity: 28% (81 aa)

YEVIKELGRGSFGVVYLGIKQG--EELAIKTIKKDKIQRSQKLTELLDSEKQLLSTIKSNHITKLFEFFETDKNCFLAMEYCNG--GTLEKYIQQKKL--
||.....|.|.||.||.... .  .. ||| ||           | . .| |.|.  .  .| ||...|.. .. .. ||||.|  |.| .||....   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----ISEKEAKGYLIQLLSGFKDLHSHLVIHRDIKLENIMRHFPNGQTGNDTYDNKNVVLKIADLGLAKEMKDEMIAHTYAGTVLTMAPEILKQKSYGF-
    ..| .|. |. |.... . .||| .||||.| |||.                  ..||.| |||...      .|. ||   ||||.|   .||. 
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---------------HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKC

EVDVYSLGVILYYMVQGKYPFYENNDTKLLQKIKEQNIQFKDENPVSLEFQDLIKQMLKYNKKQRITWSGIIN-------HKAI
..|..|.|.||| |. |. ||.  .. ....||.            | |. |.|...|... ..|.|   . .       |  .
KCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 6347.AA Ciliate-E2-Unclassified 17-282 27 1.2e-81 277.56 In-house 1-352 (352) Show / Hide 
Range on Protein: 17-282
Range on HMM: 1-352/352
Sequence Identity: 27% (101 aa)

YEVIKELGRGSFGVVYLGIK--QGEEL-----AIKTIKKDKIQRSQKLTELLDSEKQLL------------------STIKSNHITKLFEFFETDKNCFL
|..|| .|.|.||.||. ..  |. ..     ..| ..... |  .|  |.. ..|..                   . ... .| |.|. |....|...
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

AMEYCNGGTLEKYIQQK-----------------KLISEKEAK-----GYLIQLLSGFKDLHSHL-VIHRDIKLENIMRHFPNGQTGNDTYDNKNVVLKI
 ||||.||.|..||...                 | ..|..||      |. |.|.|.. ||. . .||||||.|||. .  ..          |  .||
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK----------NYYIKI

ADLGLAK--------EMKD---------EMIAHTYAGTVLTM----APEILKQKSYG----FEVDVYSLGVILYYMVQGKYPFYENNDTK----------
.|.|..|        . ..         .....| .||  .|    |||.|... |.    ...|..|||||||.|. |.|||| ||...          
IDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWIN

------LLQKIKEQNIQFKDENP------VSLEFQDLIK----QMLKYNKKQRITWSGIINHKAI
      |.|.||..||||. ...      .| | .|.|.    .|||.| ..|||.. |.||  .
NAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 6347.AA CAMK 22-282 22 6.7e-79 253.71 In-house 1-425 (425) Show / Hide 
Range on Protein: 22-282
Range on HMM: 1-425/425
Sequence Identity: 22% (98 aa)

ELGRGSFGVVYLGIKQ-G-------------EELAIKTIKKDKIQR------------------------SQKLTELLDSEKQLLST-------IKSNHI
.|||||||.|.|.|                 .. ||| |.|.|..                         ..|  . . .| .....       ..  .|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

TKLFEFFET-------------------DKNCFLAM---EYCNGG----TLEKYIQQKKL---------------ISEKEAKGYLIQLLSGFKDLHSHLV
 ||.|..|.                   ||.... |   ||| ||     |  ||....                ..|.||. |  |..|. . .||| .
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDIKLENIMRH--------------FPNGQTGNDTYDNKNVVLKIADLGLAKEMKD------------------------EMIAHTYAGTVLTMA-PE
.|||.|.|||.                |.          ..|  .||.| |.|.....                            .|. ||   || ||
VHRDLKPENILLDDNNDDSDPVEHDEIFD----------WNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPE

ILKQKS--------------YGFEVDVYSLGVILYYMVQGKYPFYEN-------------NDTKLLQKIKEQNIQFKDEN--------------------
.|..|.              ||...|. |.||||| |. |..|||.              || .|..||.. . .| ..                     
VLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEF

--PVSLEFQDLIKQMLKYNKKQRITWSGIINHKAI
   || | .|||..||... ..|.| . . ||. .
HHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 6347.AA CAMKL 17-282 30 4.1e-77 245.6 In-house 1-297 (297) Show / Hide 
Range on Protein: 17-282
Range on HMM: 1-297/297
Sequence Identity: 30% (96 aa)

YEVIKELGRGSFGVVYLGIKQ---GEELAIKTIKKDKIQRSQKLTEL-----------LDSEKQLLSTIK---SNHITKLFEFFETDKN------CFLAM
|...|.||.||||.| |.. .   ||. ||| |.|.||.  .. .             .  | |... ..     .| ||.| .||...      ..| |
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCNGGT--LEKYIQQK----KLISEKEAKGYLIQLLSGFKDLHSHLVIHRDIKLENIMRHFPNGQTGNDTYDNKNVVLKIADLGLAKEMKD-----EMI
||| ||   |  ||...    . ..|.||. |  |..|. . .||| ..|||||.|||.    . .           ..||.| |.. ....     .  
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-----------NIKIIDFGFSNMYRPCIFGPGQK

AHTYAGTVLTMAPEILKQ--K-SYGFEVDVYSLGVILYYMVQGKYPFYENNDT-------KLLQKIKEQNIQFKDENPVSLEFQDLIKQMLKYNKKQRIT
 .|  |.   |||||..   |  .|..||. |.||||| || |..|| . ..        .|. ||...  ..   . || . .|||..||. | ..|.|
LKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPT

WSGIINHKAI
   | ||.  
IHQIMNHPWM
Kinase 6347.AA Pkinase 17-282 29 2.1e-72 251.64 Pfam 1-293 (293) Show / Hide 
Range on Protein: 17-282
Range on HMM: 1-293/293
Sequence Identity: 29% (91 aa)

YEVIKELGRGSFGVVYLGIKQGEE--LAIKTIKKDKIQRSQK-----LTELLDSEKQLLSTIKSNHITKLFEFFETDKNCFLAMEYCNGG----TLEKYI
|.... .|.||||.||.....|..   |.|.|||...  ...     |     || |..  ... .| .|...||..... . ||||.||     |  ||
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-----SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

Q--QKKLI--SEKEAKGYLIQLLSGFKDLHSHLVIHRDIKLENIMRHFPNGQTGNDTYDNKNVVLKIADLGLAK---EMKDEMIAHTYAGTVLTMAPEIL
.  ... .  ||.|.| |. |.|.| . .||. .||||.|.|||. .  ||...          .||.| ||||   . ...  ..|..||   ||||..
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDA--------CVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVI

K-QKSYGFEVDVYSLGVILYYMVQGKYPFYEN------NDTKLLQKIKEQNIQFKDENPVS-------------------LEFQDLIKQMLKYNKKQRIT
. .. || .||..|.|.|||.|. |. ||..       .. .....|..  . |  ... |                    |..|.|| .|... |.|.|
RGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT

WSGIINHKAI
.  | .|. .
AEQILQHPWF
Kinase 6347.AA Ciliate-E2a 17-280 32 1.6e-66 194.81 In-house 1-273 (275) Show / Hide 
Range on Protein: 17-280
Range on HMM: 1-273/275
Sequence Identity: 32% (93 aa)

YEVIKELGRGSFGVVYLG--IKQGEELAIKTIKKDKIQRSQKLTELLDSEKQLLSTIKSNHITKLFEFFETDKNCFLAMEYCNGGTLEKYIQQKKLISEK
|..||..| |.||.|||   ...|.. |.| ..| |.. . |  | .  | .......  .| ||.|..|...| .| ||||.||.|...|.|.| . |.
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE

--EAKGYLIQLLS-GFKDLHSHLVIHRDIKLENIMRH--FPNGQTGNDTYDNKNVVLKIADLGLAKEM--KDEMIAHTYAGTVLTMAPEILKQKS-----
  |.. .. |||. |.  .|.  ..|||.|.|||.     .|..         |  .||.| |||.    ...   ..  ||   .|||.|. |      
IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSI--------QNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHK

-YGFEVDVYSLGVILYYMVQGKYPFYENNDTKLLQKIKEQNIQFKDEN---PVSLEFQDLIKQMLKYNKKQRITWSGIINHK
 |.  .|. |.|||.| .. || ||.  . .  ||..|. .|.| . .    .|.| .||.|.||... |.|||   . ||.
QYDTKCDMWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHP
Kinase 6347.AA RSK 20-282 29 2.7e-58 199.96 In-house 1-278 (278) Show / Hide 
Range on Protein: 20-282
Range on HMM: 1-278/278
Sequence Identity: 29% (87 aa)

IKELGRGSFGVVYLGIKQ-----GEELAIKTIKKDKIQRSQKLTELLDSEKQLLSTIK-SNHITKLFEFFETDKNCFLAMEYCNGGTLEKYIQQKKL---
.|.||.|..| |.|  |      | . | | .|| || ..|| |.    | . |.... .  | .|.. |.|..  .| ||||.|| | . .|..|    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

ISEKEAKGYLIQLLSGFKDLHSHLVIHRDIKLENIMRHFPNGQTGNDTYDNKNVV---LKIADLGLAKEM--KDEMIAHTYAGTVLTMAPEILK---QKS
.||.||. |. .. .  . ||.. .||||.|.|||.            ||...     .|. | |..|..  ...  ..|. .|.  ||||.||   |..
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENIL------------YDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQG

-YGFEVDVYSLGVILYYMVQGKYPFYE---NNDTKLLQKIKEQNIQFKDE--NPVSLEFQDLIKQMLKYNKKQRIT-----WSGIINHKAI
 ..  .|..||||..| |  |. ||.    ||  .....|.. .. .. .  . .| |..|||..||. . ..|..      . | .|. .
GHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 6347.AA STE 17-282 20 1e-54 188.12 In-house 1-359 (359) Show / Hide 
Range on Protein: 17-282
Range on HMM: 1-359/359
Sequence Identity: 20% (76 aa)

YEVIKELGRGSFGVVYLGIKQ-----------------GEELAIKTIKKDKIQ-------------RSQKLTELLDSEKQLLSTIK--SNHITKLFEFFE
.| |...|.|.||.||....                  ||  ||| ..... .             . ..  . .  | ....  .  . .| | .  ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TD-------KNCFLAMEYCNGGTLEKYIQQK--------------KLISEKEAKGYLIQLLSG-FKDLHSHLVIHRDIKLENIMRHFPNGQTGNDTYDNK
 .        .....|||..||.|.. |..|              . ..|.. . .. |.| |  . |||| .||||||  ||.                
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL---------------

NVVLKIADLGLAKEMKDEMI-----------------AHTYAGTVLTMAPEILKQ------KSYGFEVDVYSLGVILYYMVQGKYPFYENNDTKLLQKIK
    |..| |... . |.|                    | .||   ||||...|      | |.. .|..|||  .  |. ||.|. . .... .  | 
---VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIP

----------------EQNIQFKD-----------------ENPVSLEFQDLIKQMLKYNKKQRITWSGIIN--HKAI
                ..  ...|                    .| ||.| |.. |... ..| | |  ..  |. |
FNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 6347.AA AGC 17-146 24 6.9e-45 112.81 In-house 1-187 (395) Show / Hide 
Range on Protein: 17-146
Range on HMM: 1-187/395
Sequence Identity: 24% (46 aa)

YEVIKELGRGSFGVVYLGIKQ--------GEELAIKTIKKDK-IQRSQK-LTELLDSE------------KQLLSTIK----------SNHITK-LFEFF
.|..| .|.|||| |||  |         |.  |.| .||.. |.. .|   |   .|            .. |....          .  |.| |.  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ETDKN--CFLAMEYCN---------GG-TLEKYIQ---QKKLISEKEAKGYLIQ-------LLSGFKDLHS-HLVIHRD-IKLENIM
.....   .. |||..         ||  |  ..|   ...  .|..|. |. .       .....  ||| . .|||| .|.|||.
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENIL
Kinase 6347.AA AGC 166-282 20 6.6e-44 110.22 In-house 194-395 (395) Show / Hide 
Range on Protein: 166-282
Range on HMM: 194-395/395
Sequence Identity: 20% (43 aa)

LKIADLGLAKEMKDEM---------------------------------------------------IAHTYAG--TVLTMAPEILKQKSYGFEVDVYS-
.|..| ||.||.....                                                    ..|  |  |   ||||||    ||...| .| 
IKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSF

-LGVILYYMVQGKYPFYENNDT----------KLLQKIK------EQNIQFK--------DENPVSLEFQDLIKQMLKYNKKQRIT----------WSGI
 ||...| |. |. ||| .|.           .. |||.      .....|         ..  .| | .||||..|. . ..|..           . |
GLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEI

INHKAI
 ||.  
KNHPWF
Kinase 6347.AA TyrKc 17-282 20 1.3e-16 45.73 SMART 1-280 (280) Show / Hide 
Range on Protein: 17-282
Range on HMM: 1-280/280
Sequence Identity: 20% (63 aa)

YEVIKELGRGSFGVVYLGIKQGEELAIKTIKKDKIQRSQKLTELLDSEKQLLSTI--KSNHITKLFEFFETD-------KNCFLAMEYCNGGTLEKYIQQ
 . .|.||.| ||.||.|.   .. |.|..|.|.        | . .| .... .  .  .| .|.    ..       .  .. |||. .| | .|.. 
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KKL-ISEKEAKGYLIQLLSGFKDLHSHLVIHRDIKLENIMRHFPNGQTGNDTYDNKNVVLKIADLGLAKEMKDE--------MIAHTY--AGT-VLT---
..  .. |.   . .|  .|   |||. .||||.   |.. . ..             . ||.| ||... .|.        .. ..    |  .|    
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-------------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRW

MAPEILKQKSYGFEVDVYSLGVILYYMV-QGKYPFYE-----NNDTKLLQKIKEQNIQFKDENP-------VSLEFQDLIKQMLKYNKKQRITWSGIINH
|||| .. . . .. ||.| || .. .   |. | ..      ... .....|. .   . .|.        . |  ...||  ... ..| | | |  |
MAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--H

KAI
. .
ECF
Kinase 6347.AA Pkinase_Tyr 17-140 23 9.4e-10 33.65 Pfam 1-137 (270) Show / Hide 
Range on Protein: 17-140
Range on HMM: 1-137/270
Sequence Identity: 23% (32 aa)

YEVIKELGRGSFGVVYLGIKQ------GEELAIKTIKKDKIQRSQ-KLTELLDSEKQLLSTI-KSNHITKLFEFFE-TDKN--CFLAMEYCNGGTLEKYI
 . .|.||.|.||.||.|.        . . |.|.. |..   .| .. ...  | ...... .  .| .|       ..    .. |||. .| | .| 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

QQ----KKLISEKEAKGYLIQLLSGFKDLHSHLVIHRDI
..    |. .. |.  .. .|  .|   |.|.  ||||.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL
Kinase 6347.AA Pkinase_Tyr 193-217 36 0.340134 4.67 Pfam 181-205 (270) Show / Hide 
Range on Protein: 193-217
Range on HMM: 181-205/270
Sequence Identity: 36% (9 aa)

MAPEILKQKSYGFEVDVYSLGVILY
|||| .. . .  . ||.| || ..
MAPECINYGKFTTKSDVWSFGVLMW
Kinase 6347.AA ULK 343-595 23 4e-61 209.37 In-house 17-324 (324) Show / Hide 
Range on Protein: 343-595
Range on HMM: 17-324/324
Sequence Identity: 23% (74 aa)

YLAIDTDNS--NKLVIVKQVISDYYTLKEYNQT----ADQIKQVFKIIQKIN---QEN--ILKINLITMSK--NKFYIVSEYLKYGNLQTINSTNKK---
| ... ..   |..| .|..  ..   |...|.     ...|.. .|..|..    .|  | |   .....  | .||. ||   |.|...  .|||   
YKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPE

------FLQQEILLLLINILISLKWLHENGIIHRNINLKSIYIAKLNES----------INFITQFKLGGFKNCYKFEQRSSYAKS---KYKGMNFYTAP
      . .||..  .. |.  .|.||...|||| | .  | | . ...          .  |. | .. . ... .||   .      ..||   | ||
TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAP

EILS----DKIYT-QTVDIYSLGVVLHELVYGYVP---YIGNTKQ----ELIDN-------IYNQRKNHDT--EVEGFSKELLELIEKMIIPDPKQRINF
.||.     | |.   .||.|||....|..||..|   .  |. .    .||.|       |.||  ...   .   .|.|. .|| .|.. |.|.||..
QILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISW

EQLWSQDLI
|.. .  ..
EEIFNHPWF
Kinase 6347.AA ULK 343-595 22 2.4e-58 200.14 In-house 16-329 (329) Show / Hide 
Range on Protein: 343-595
Range on HMM: 16-329/329
Sequence Identity: 22% (71 aa)

YLAIDTDNS---NKLVIVKQVISDYYTLKEYNQT----ADQIKQVFKIIQKINQE--------NILKINLITMSK--NKFYIVSEYLKYGNLQTINSTNK
| ... ..    |..|..|.. ...   |...|.     ...|.  ||..|....        || |   .....  | .||. ||   |.|... ..||
YKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNK

K----------FLQQEILLLLINILISLKWLHENGIIHRNINLKSIYIAKLNES----------INFITQFKLGGFKNCYKFEQRSSYAKS---KYKGMN
|          . .||..  .. ||  .|.||...|||| | .  | | . ...          .  |. | .. . .. ..||.  .. .   ...|  
KLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTP

FYTAPEILS----DKIYT-QTVDIYSLGVVLHELVYGYVPYIGNTKQELIDNIYNQRKN-----------HDTEVEG------FSKELLELIEKMIIPDP
 | ||.||.     | |.  ..||.|||....|..||..|. .. .......|... .|           . .. .       .|.|. .|| .|.. |.
LYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDE

KQRINFEQLWSQDLI
|.||..|.| .  ..
KDRISWEELFNHPWF
Kinase 6347.AA Ciliate-E2 326-595 19 9.3e-29 95.83 In-house 24-365 (365) Show / Hide 
Range on Protein: 326-595
Range on HMM: 24-365/365
Sequence Identity: 19% (71 aa)

QCKQKLIPITQNN---------FVNNYLAIDTDNSNKLVIVKQVISDYYTLKEYNQTADQIKQVFKIIQKINQENILKIN--LITMSKNKFYIVSEYLKY
|... .. |. ..         . ... |. . . |.. ..||.|. . ....  .   .| .  .| ...|  ||.|.    .....|..|.| ||...
QKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINC-FY--KKI-NEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQG

GNLQT------INSTNK-----KFLQQEILLLLINIL---------------ISLKWLHENG-IIHRNINLKSIYIAKLNESINFITQFKLGGFKNCY--
|.|.       ......     .|  .||. .   ||                 |. ||... ||||.| .  | .             |.  | ..   
GDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------------IKIIDFGLSKKY

-KFEQRSSYAKSKYK----------------------------GMNFYTAPEILS---------DKIYTQTVDIYSLGVVLHELVYGYVPYIGNTKQELI
 ...|. .. |.  |                            |.  | |||||.          | |.  .||.||||.|.|...|. |.     |. .
DDDNQNRTH-KQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF----QQQIK

DNIYNQRKNHDT-----------EVEGFSKELLELIEK----MIIPDPKQRIN-FEQLWSQDLI
.. .. .... .           . .  |.|   || |    |.  ||..||. .||.     .
QCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 6347.AA Ciliate-E2-Unclassified 343-595 19 1.1e-27 93.13 In-house 16-352 (352) Show / Hide 
Range on Protein: 343-595
Range on HMM: 16-352/352
Sequence Identity: 19% (68 aa)

YLAIDTDNSNKLVIVKQVI-SDYYTLKEYNQTADQIKQVFKIIQKIN---QE--------------NILKINLITM--SKNKFYIVSEYLKYGNLQTINS
|.... ..  .. . |. . .  |  | ...   .|..  |......   |.              ........ .  .|...||| ||...|.|. . .
YKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIK

TNKK-----------------FLQQEIL-----LLLINILISLKWLHENG-IIHRNINLKSIYIAKLNESINFITQFKLGGFKNCYKFEQR---------
 .||                 |  |...      ..  ||  |. ||... ||||.| .  | . . ..      . |. .| ...| .|          
KRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK----NYYIKIIDFGISKKYQQNNNCDTNQQQ

------SSYAKSKYKGMNF---YTAPEILSDKIYTQT----VDIYSLGVVLHELVYGYVPYIGNTKQE----------------LIDNIYNQRKNHDTEV
      .  ....    |.   |||||.|  . | ..    .||.||||.|.|...|| |. .|.. .                |..||...  . . . 
KMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFP

E-----GFSKELLELIE----KMIIPDPKQRINFEQLWSQDLI
.     . |.|  ..|.    ||.  .|..||.|||.    ..
WQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 6347.AA AGC 504-584 28 2.1e-25 61.25 In-house 273-374 (395) Show / Hide 
Range on Protein: 504-584
Range on HMM: 273-374/395
Sequence Identity: 28% (30 aa)

YTAPEILSDKIYTQTVDIYS--LGVVLHELVYGYVPYIGNT----------KQELIDNIYNQR----KN---------HDTEVEGFSKELLELIEKMIIP
| |||||    |....|..|  ||... |...|| |. |..          . |. ..| | |    ..         . .|.. ||.|.  ||.|.. .
YMAPEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCK

DPKQRI
||..|.
DPEKRL
Kinase 6347.AA S_TKc 328-595 19 3.2e-19 71.09 SMART 1-231 (231) Show / Hide 
Range on Protein: 328-595
Range on HMM: 1-231/231
Sequence Identity: 19% (54 aa)

KQKLIPITQNNFVNNYLAIDTDNSNKLVIVKQVISDYYTLKEYNQTADQIKQVFKIIQKINQENILKINLITMSKNKFYIVSEYLKY--GNLQTINSTNK
 ..| .| .  |   |...... ....| .|..              ..|..  .| .| . .|| |.  .  . ...|.| ||.    |.| ..   ..
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK-------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG

K------FLQQEILLLLINILISLKWLHENGIIHRNINLKSIYIAKLNESINFITQFKLGGFKNCYKFEQRSSYAKSKYKGMNFYTAPEILSDKIYTQ-T
.      |   ..  ..  |.  |. .|..||||| .    | . .         . |.. |  . ..        . . |  .| |||.|    |.   
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---------HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCK

VDIYSLGVVLHELVYGYVPYIGNTKQELIDNIYNQRKNHDTEVEGFSKELLELIEKMIIPDPKQRINFEQLWS-------QDLI
.|..|.|..| |...|| |.   . |.....|              |.|....|.|.   ||..|.   ..            .
CDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 6347.AA CAMK 504-588 22 1.8e-17 52.22 In-house 285-418 (425) Show / Hide 
Range on Protein: 504-588
Range on HMM: 285-418/425
Sequence Identity: 22% (30 aa)

YTA-PEILSDKI--------------YTQTVDIYSLGVVLHELVYGYVPYIGN-------------TKQELIDNIYNQRKN-HDTEVEG-----------
| | ||.|. |               |.. .|. |.||.|  .. || |. |              . .||  .| . . .  . .. .           
YMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWD

---------FSKELLELIEKMIIPDPKQRINFEQ
         .|.|   || ||  .||..|.. ||
DISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQ
Kinase 6347.AA Pkinase 503-595 22 3.1e-17 62.04 Pfam 176-293 (293) Show / Hide 
Range on Protein: 503-595
Range on HMM: 176-293/293
Sequence Identity: 22% (26 aa)

FYTAPEILS-DKIYTQTVDIYSLGVVLHELVYGYVPYIGN------TKQELIDNIYNQRKNHDTEVE------------------GFSKELLELIEKMII
.| |||..  .. |.. ||..|.|..|.|.. |. |. |       .....|..|   .   | . .                    |.|....|.... 
WYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLC

PDPKQRINFEQLWSQDLI
.|||.|...||.   . .
KDPKKRPTAEQILQHPWF
Kinase 6347.AA CAMKL 504-595 28 2.1e-16 48.74 In-house 199-297 (297) Show / Hide 
Range on Protein: 504-595
Range on HMM: 199-297/297
Sequence Identity: 28% (29 aa)

YTAPEILSD--KIYT-QTVDIYSLGVVLHELVYGYVPYIGNT----KQELIDNIYNQRKNHDTEVE---GFSKELLELIEKMIIPDPKQRINFEQLWSQD
| ||||...  | |  . ||| |.||.|  .|.||.|  . |    ... | . |.. . . ..       | ..  || ||  ..|..|.. .|. .  
YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHP

LI
  
WM
Kinase 6347.AA Ciliate-E2a 504-589 31 4.1e-16 43.96 In-house 176-269 (275) Show / Hide 
Range on Protein: 504-589
Range on HMM: 176-269/275
Sequence Identity: 31% (30 aa)

YTAPEILSDKI------YTQTVDIYSLGVVLHELVYGYVPYIGNTKQELIDNIYNQRKNHDTEV--EGFSKELLELIEKMIIPDPKQRINFEQL
| |||.|  |       |.. .|. |.||... |..|. |. | | .| . ....   . .  .  | .|||   |. ||  .|||.||. .|.
YVAPEVLNNKEVLKHKQYDTKCDMWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQA
Kinase 6347.AA RSK 504-589 27 1e-12 43.11 In-house 174-272 (278) Show / Hide 
Range on Protein: 504-589
Range on HMM: 174-272/278
Sequence Identity: 27% (27 aa)

YTAPEILS----DKIYTQTVDIYSLGVVLHELVYGYVPYIG---NTKQELIDNIYNQRKNHDTE-VEGFSKELLELIEKMIIPDPKQRIN-----FEQL
| |||.|     .. ... .|..||||...|.  |..|. |   |...|....| . . . . .  .  |.|  .|| ||   ||..|..      |..
YMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEI
Kinase 6347.AA STE 504-595 21 6.2e-10 31.38 In-house 228-359 (359) Show / Hide 
Range on Protein: 504-595
Range on HMM: 228-359/359
Sequence Identity: 21% (28 aa)

YTAPEILS------DKIYTQTVDIYSLGVVLHELVYGYVPYIG-NTK---QELIDNIYNQR---------------KNHDTEVEG-------------FS
. |||...      || |.  .||.||| .. |.. | .|.   .      . ..|.. |.               ..|  ..|.             .|
WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWS

KELLELIEKMIIPDPKQRINFEQLWS--QDLI
.|. . |.|  . ||..| . .|| .     |
PEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 6347.AA Pkinase_Tyr 505-554 30 4.6e-07 24.54 Pfam 181-232 (270) Show / Hide 
Range on Protein: 505-554
Range on HMM: 181-232/270
Sequence Identity: 30% (16 aa)

TAPEILSDKIYTQTVDIYSLGVVLHELVY-GYVP-YIGNTKQELIDNIYNQR
.||| ......|   |..| ||.. |..  |  | | | . .|... || ..
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDG
Kinase 6347.AA STE 328-456 18 3e-06 18.45 In-house 1-178 (359) Show / Hide 
Range on Protein: 328-456
Range on HMM: 1-178/359
Sequence Identity: 18% (34 aa)

KQKLIPITQNNFVNNYLAIDTDNS--------------NKLVIVKQVISDYYTLKEYN------------QTADQIKQVFKIIQKIN--QENILKINLIT
 ...  | . .|   |.|.. .|.              .... .||.  .  . |. .            .  .||..  || .| |   .|| |     
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

MSK-------NKFYIVSEYLKYGNLQTINSTNKKFL--------------QQEILLLLINILIS-LKWLHENGIIHRNI
. .       .. .|. ||. .| |  |  .... .               ..|   .  ||   |. ||...|||| |
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDI
Kinase 6347.AA AGC 401-454 20 0.005384 1.99 In-house 102-178 (395) Show / Hide 
Range on Protein: 401-454
Range on HMM: 102-178/395
Sequence Identity: 20% (16 aa)

SKNK--FYIVSEYLK----------YGNLQTINS---TNKKFLQQEILLLLIN-------ILISLKWLHE-NGIIHR
.|..   |.| ||..           . | ...     ...|  ...   .         |.  |  ||. .|||||
DKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHR
Kinase 6347.AA Pkinase 382-454 28 0.018831 9.75 Pfam 52-132 (293) Show / Hide 
Range on Protein: 382-454
Range on HMM: 52-132/293
Sequence Identity: 28% (23 aa)

KIIQKINQENILKINLITMSKNKFYIVSEYLKYG----NLQTINS--TNKKF--LQQEILLLLINILISLKWLHENGIIHR
.| ...| .||...  . ..|.. |.| ||.  |     | .. |   ...|    .|.   .  ||  |. .|..|||||
QIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHR
Kinase 6347.AA CAMK 401-456 15 0.018936 2.9 In-house 128-205 (425) Show / Hide 
Range on Protein: 401-456
Range on HMM: 128-205/425
Sequence Identity: 15% (12 aa)

SKNKFYIVS---EYLKYG----N-LQTINSTNK-------------KFL-QQEILLLLINILISLKWLHENGIIHRNI
.....|.|    ||   |      .. | .  .             . .  .|   .   |.  .. .|...|.|| .
KDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDL
Kinase 6347.AA Ciliate-E2a 382-454 28 0.035835 2.22 In-house 51-126 (275) Show / Hide 
Range on Protein: 382-454
Range on HMM: 51-126/275
Sequence Identity: 28% (22 aa)

KIIQKINQENILKINLITMSKNKFYIVSEYLKYGNLQ-TINSTNKKFLQ-QEILLLLINIL-ISLKWLHENGIIHR
.|.....  ||.|.  . ...| .|.| ||.. | |   |.   . |   |||  .. ..|   |  .| ..|.||
NIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEIQEICDIMQQLLWQGLHYMHQRNIMHR
Kinase 6347.AA RSK 436-454 42 0.239201 1.14 In-house 110-128 (278) Show / Hide 
Range on Protein: 436-454
Range on HMM: 110-128/278
Sequence Identity: 42% (8 aa)

LINILISLKWLHENGIIHR
. .|   .. ||. |||||
MAEIVLAVEHLHQQGIIHR