26010

Species: Tetrahymena
Alias: PreTt26010, 613, TTHERM_00290780, 26.m00362, 3688.m00154, 26010
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
26010.AA Protein None 464 None Fasta, JSON
26010.kin_dom Protein Kinase Domain None 259 None Fasta, JSON
26010.NA RNA None 1395 None Fasta, JSON

Protein domain

Protein domains of 26010.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 26010.AA AGC 40-298 30 3.6e-169 441.62 In-house 1-395 (395) Show / Hide
Range on Protein: 40-298
Range on HMM: 1-395/395
Sequence Identity: 30% (121 aa)

FELLNVIGEGKFGTVLLVKKK------DSGKLFAMKIIK---KSIIRKRQFAHRIIQE------------KDILAFCN----------NNFMTK-LHYSF
||.| |||.| ||.| ||.||      |.||..|||..|   | .|.|..  .... |            ..||. ||          . | .| |||||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QNQNN--LFLILDYCS---------GG-DLFNYIS---KKNTISEKDAKFYAAQ-------IVLMLEYLHS-QNIVYRD-LKPENILIEKNGYLKLGDFG
|....  |.....|..         || .|| ..    |. . .|. |.||||.       ||| |||||| ..|..|| |||||||. ..|..|| |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

YARQNMDS---------------------------------------------------IEAKSVCG--TPHYFPPEMITREGHGKPVDWWA--LGCVIY
 . ..|..                                                     ... ||  ||.| .||..    .||..|||.  |||..|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMVFGATPFDDSN----------QKILFDRIK------NSPVIFENDKN------KKVSNNFKDIVNKLLKKNQNERLGTAS-------IEEIKSHPWF
||..| .|| . |          .. .|..|.      | .| | ....      ...|.. ||...|||.|. ..|||.         .||||.||||
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF

Kinase 26010.AA AktR 40-298 49 9.5e-162 543.65 In-house 1-268 (268) Show / Hide
Range on Protein: 40-298
Range on HMM: 1-268/268
Sequence Identity: 49% (132 aa)

FELLNVIGEGKFGTVLLVKKK-DSGKLFAMKIIKKSIIRKRQFAHRIIQEKDILAFCNNN-FMTKLHYSFQNQNNLFLILDYCSGGDLFNYISKKNTISE
|......|.|.||.| ||.|| |..|..|||.|||. |..|...|..|.|..|...|.|. |. ||||.||....||.|..|| ||.||....||...||
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

KDAKFYAAQIVLMLEYLHSQ-NIVYRDLKPENILIEKNGYLKLGDFGYAR-QNM--DSIEAKSVCGTPHYFPPEMITR-EGHGKPVDWWALGCVIYEMVF
..|.||.|||.|.|||||.. ||.||||||||||....|..|..|||... |.|  .. .|.|.||||.|..|||||. .||.|.|||||.|..|||||.
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GATPFDDSNQKILFDRIKNSPVIFENDKNKKVSNNFKDIVN-KLLKKNQNERLG--TASIEEIKSHPWF
| .||...||...|..||... ..........|...||... |||.||.|.|||  ....|||||||||
GCPPFYHKNQNQMFQKIKIKQ-QNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF

Kinase 26010.AA Akt 40-298 47 3e-139 447.84 In-house 1-264 (264) Show / Hide
Range on Protein: 40-298
Range on HMM: 1-264/264
Sequence Identity: 47% (126 aa)

FELLNVIGEGKFGTVLLVKKKDSGKLF-AMKIIKKS-IIRKRQFAHRIIQEKDILAFCNNNFMTKLHYSFQNQNNLFLILDYCSGGDLFNYISKKNTISE
|..|.|.| | || |.||||||..|.. |||..||. || |.|..| ...|. ||  ||..| ..||||||.|..|....|||.||.||.....|...||
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEH-TKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSE

KDAKFYAAQIVLMLEYLHSQNIVYRD-LKPENILIEKNGYLKLGDFGYARQN-MDS-IEAKSVCGTPHYFPPEMITREGHGKPVDWWA-LGCVIYEMVFG
. |.||.|.|.| .|.|||.||.||| |||||||. |.|...| ||| ...| .    ..|..|||| | .||..   ||.|.||||. ||||.||| .|
DRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCG

ATPFDDSNQKILFDRIKNSPVIFENDKNKKVSNNFKDIVNKLLKKNQNERLG-TAS-IEEIKSHPWF
. || . ... .|. |||.|| | .   ...|.. ||....||.|. ..||| . . ..|||.||||
RPPFYNQDHHQMFKKIKNQPVKFPDK--DWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF

Kinase 26010.AA PKA 40-298 43 2.7e-122 412.58 In-house 1-263 (263) Show / Hide
Range on Protein: 40-298
Range on HMM: 1-263/263
Sequence Identity: 43% (116 aa)

FELLNVIGEGKFGTVLLVKKKDSGKLFAMKIIKKSIIRKRQFAHRIIQEKDILAFCNNNFMT-KLHYSFQNQNNLFLILDYCSGGDLFNYISKKNTISEK
||.....| | ||.| |...|.||. .|||..||. | ..   .... || ||  ... |   |. ..||. ..|.....|..||..| |. |.   |..
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

DAKFYAA-QIVLMLEYLHSQNIVYRDLKPENILIEKNGYLKLGDFGYARQNMDSIEAKSVCGTPHYFPPEMITRE-GHGKPVDWWALGCVIYEMVFGATP
.|||||| ||||.|||||||||.||||||||||| |||..|..||| | ...|. . ...|||| |..||.|... ||||.|||||||..||||..| .|
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFA-KKVDD-RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPP

FDDS--NQKILFDRIKNSPVIFENDKNKKVSNNFKDIVNKLLKKNQNERLGTASI--EEIKSHPWF
| |.  ..  ....| |  . |..  .... | ||| ..||| .. ..|.|. .   . || |.||
FYDHNRDPMQIYEKICNGKIKFPRHFDSDA-NYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF

Kinase 26010.AA SGK 40-298 38 1.1e-117 365.07 In-house 1-283 (283) Show / Hide
Range on Protein: 40-298
Range on HMM: 1-283/283
Sequence Identity: 38% (110 aa)

FELLNVIGEGKFGTVLLVKKKDS------------------GKLFAMKIIKKSIIR-------KRQFAHRIIQEK-DILAFCNNNFMTKLHYSFQNQNNL
|..|.|||.| || |..||.||                   .|..|||...|  |.       |.  .  |  |. .||   .  |  .|||.||..  |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

FLILDYCSGGDLFNYISKKNTISEKDAKFYAAQIVLMLEYLHSQNIVYRDLKPENILIEKNGYLKLGDFGYARQNM-DSIEAKSVCGTPHYFPPEMITRE
.. .||  ||..|... . .  .|  |.||||.||. |||||||.|.||||||||||    |...| ||| . ... .. . .. |||| |  ||..  .
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

GHGKPVDWWALGCVIYEMVFGATPFDDSNQKILFDRIKNSPVIFENDKNKKVSNNFKDIVNKLLKKNQNERLGTA-SIEEIKSHPWF
.|.. |||| |||| ||| .|. || . | ....| | |.|  .     . .||  .|. . ||.|.. .||||.   .|||.||.|
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIP----PQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF

Kinase 26010.AA S_TKc 40-298 36 9.69999999999e-105 355.18 SMART 1-231 (231) Show / Hide
Range on Protein: 40-298
Range on HMM: 1-231/231
Sequence Identity: 36% (98 aa)

FELLNVIGEGKFGTVLLVKKKDSGKLFAMKIIKKSIIRKRQFAHRIIQEKDILAFCNNNFMTKLHYSFQNQNNLFLILDYCSG--GDLFNYISKKNT---
.|.|..||.| ||.| ....|..|...|.||||           .|..| .||   .  .  ||...||. ..|.....||.|  |||| || |...   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---ISEKDAKFYAAQIVLMLEYLHSQNIVYRDLKPENILIEKNGYLKLGDFGYARQNMDSIEAKSVCGTPHYFPPEMITREGHGK-PVDWWALGCVIYEM
   ..| .|.||..||.. |||.||..|..|||||||||. .   .|..||| |||       ...||||.| .||..   |.|| ..|||..||..|||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

VFGATPFDDSNQKILFDRIKNSPVIFENDKNKKVSNNFKDIVNKLLKKNQNERLGTASIEE----IKSHPWF
. | .||.  ... .|..|.              |  .||...|.|.|. ..|..   . .    ||.||||
LCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 26010.AA RSK 43-298 39 1.5e-104 353.66 In-house 1-278 (278) Show / Hide
Range on Protein: 43-298
Range on HMM: 1-278/278
Sequence Identity: 39% (109 aa)

LNVIGEGKFGTVLLVKKK---DSGKLFAMKIIKKSIIRKRQF-AHRIIQEKDILAFCN-NNFMTKLHYSFQNQNNLFLILDYCSGGDLFNYISKKNT---
| | |.| .| | |..|.   |.|...|||..||. |..||  . .  .| .||. |.   |  .|||.|| .  |.||..||.||.||  ..|. .   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

ISEKDAKFYAAQIVLMLEYLHSQNIVYRDLKPENILIEK---NGYLKLGDFGYARQ-NMD-SIEAKSVCGTPHYFPPEMIT----REGHGKPVDWWALGC
.||..|.||.|.||| .|.||.| |..||||||||| .    .| .|| ||| ..| . | .  ... |.| .| .|||..    ..||.| .||| ||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

VIYEMVFGATPFDD---SNQKILFDRIKNSPVIFENDKNKKVSNNFKDIVNKLLKKNQNERLG--TASIEEIKSHPWF
..||| .|..||     .|.| ...||..    .. . ....|...||...|.|... . |||     .||||.||||
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase 26010.AA RSK-Unclassified 40-298 37 3.7e-102 321.74 In-house 1-283 (283) Show / Hide
Range on Protein: 40-298
Range on HMM: 1-283/283
Sequence Identity: 37% (106 aa)

FELLNVIGEGKFGTVLLVKKKDSGKLFAMKIIKKSIIRKRQFAHRIIQEKDILAFCNNNFMTKLHYSFQNQNNLFLILDYCSGGDLFNYIS--KKNTISE
|.    || | || | ||.|||. ...|||. .|. . ...   ... |..|.|  |  |  .| .||| |  |.|...|| |||.|      |.  ..|
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

KDAKFYAAQIVLMLEYLHSQNIVYRDLKPENILIEKNGYLKLGDFGYARQN----------------------MDSIEAKSVCGTPHYFPPEMITREGHG
 |..|||. ... ||||| . ..||||||.||. .. |  .| ||.   |                        ..  ..| |||  |  |||| | ||.
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHT

KPVDWWALGCVIYEMVFGATPFDDSNQKILFDRIKNSPVIFENDKNKKVSNNFKDIVNKLLKKNQNERLGTASI--EEIKSHPWF
| |||| || |.||| || .|.   |.  .|  |   .| | .|  . .||| .| . |||..|   |||  .   ..|| || |
KAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHD--SYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF

Kinase 26010.AA Ciliate-E2-Unclassified 40-298 29 8.9e-96 324.49 In-house 1-352 (352) Show / Hide
Range on Protein: 40-298
Range on HMM: 1-352/352
Sequence Identity: 29% (105 aa)

FELLNVIGEGKFGTVLLVKKKDSGKLFAMKIIKKSIIRKRQFAHR---------IIQEKD-------------ILAFCNNNFMTKLHYSFQNQNNLFLIL
.... .||.| ||.| ....|. ....|||..||..|.|..   .         ....|              ||  ... |  |..| ||...|.....
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

DYCSGGDLFNYISKKNT-----------------ISEKDAK-----FYAAQIVLMLEYLHSQN-IVYRDLKPENILIEKNG---YLKLGDFGYAR-----
.|| ||||..||.|...                 ..|. ||     ||.|||.. |||||..| |..||.||||||. .||   |.|. ||| ..     
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

-----------QNMDSIEAKSVCGTPHYF----PPEMITREGHG----KPVDWWALGCVIYEMVFGATPFDDSNQKI----------------LFDRIKN
           |. .. .....|||| |     .||.. .....    . .|.|.||...|||.||  ||.| |...                |.. ||.
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

SPVIFENDKN----KKVSNNFKDIVN----KLLKKNQNERLGTASIEEIKSHPWF
 .. | . ..    |..|.. ||..|    |.||||.|.|.   ..|.|. ||||
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRI---TFEQILNHPWF

Kinase 26010.AA Ciliate-E2 40-298 26 1.3e-90 307.38 In-house 1-365 (365) Show / Hide
Range on Protein: 40-298
Range on HMM: 1-365/365
Sequence Identity: 26% (102 aa)

FELLNVIGEGKFG-----TVLLVKK------------------KDSGKLFAMKII-------KKSIIRKRQFAH----RIIQEKDILAFCNNNFMTKLHY
......||.| ||     .| .|.|                  |. .|..||||.       .|..|.  .  .    .| .|| || . |...  |...
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKI-NEKNILEQLNHPNIIKMYE

SFQ--NQNNLFLILDYCSGGDLFNYISKKNTIS-----------EKDAK---------------FYAAQIVLMLEYLHSQN-IVYRDLKPENILIEKNGY
.||  ..||..|...||.||||| || .... .           || .|               ||.|.|.| ||||||.| |..||.||||||.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

LKLGDFGYARQNMDSIEAKS--------------------------------VCGTPHYFPPEMITREG---------HGKPVDWWALGCVIYEMVFGAT
.|. |||..... |. . ..                                .||||.| .||.. ...         ... .|.|.||...|||.|| .
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFDDSNQKILFDRIKNSPVIFEND--------------KNKKVSNNFKDIVNK----LLKKNQNERLGTASIEEIKSHPWF
||        .. ||. .. | .               ..||.|.. ||. .|    .|.|....|..  ..|.|. ||||
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT--GWEQILNHPWF

Kinase 26010.AA Pkinase 40-298 32 4.3e-90 310.4 Pfam 1-293 (293) Show / Hide
Range on Protein: 40-298
Range on HMM: 1-293/293
Sequence Identity: 32% (98 aa)

FELLNVIGEGKFGTVLLVKKKDSGKLFAMKIIKKSIIRKRQFAHRII-QEKDILAFCNNNFMTKLHYSFQNQNNLFLILDYCSGG----DLFNYIS--KK
.... .||.| ||.| . ..|..||..|.|||||. ... .  ...  .|  |.. .|  .  .|...|.. ... ....|| ||    ||| |||  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NTI--SEKDAKFYAAQIVLMLEYLHSQNIVYRDLKPENILIEKNGYL----KLGDFGYARQ--NMDSIEAKSVCGTPHYFPPEMIT-REGHGKPVDWWAL
...  ||...|||. ||.  |||.||..|..|||||||||| .||..    |..||| |.|  .  .  ....||||.| .|| |  ....|..||.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCVIYEMVFGATPFDDS------NQKILFDRIKNSPVIFENDKNKKVS-----------------NNFKDIVNKLLKKNQNERLGTASIEEIKSHPWF
||..|||..| .||...      .|. ...||.  |. |. ..   .|                  ..||.....|.|. ..|..   .|.|. ||||
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT---AEQILQHPWF

Kinase 26010.AA RSK 40-298 37 1.1e-87 297.56 In-house 1-271 (271) Show / Hide
Range on Protein: 40-298
Range on HMM: 1-271/271
Sequence Identity: 37% (102 aa)

FELLNVIGEGKFGTVLLVKKK---DSGKLFAMKIIKKSIIRKR-QFAHRIIQEKDILAFCNNNFMTKLHYSFQNQNNLFLILDYCSGGDLFNYISKKNTI
.||. .||.| |. | ..||.   |.....|||||||. .  . .   .   | .||.  .  |  ||||.|| . ....|.| . |||||  ..|.   
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR--VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMF

SEKDAKFYAAQIVLMLEYLHSQNIVYRDLKPENILIEKN----GYLKLGDFGYARQNMDSIE-AKSVCGTPHYFPPEMITREGHGKPVDWWALGCVIYEM
||...|||.| | | .|||||| ||.|||||||||.       | .|. ||| | |  |  . ... |.|  |  ||.. | ||.. .||| .| . |||
SEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEM

VFGATPFDDSNQKILFDRIKNSPVIF---ENDKNKKVSNNFKDIVNKLLKKNQNERLGT--ASIEEIKSHPWF
  |.|||   . . ... |.. ..           ..|   || . ..|. . . |||.    .|.||.||||
LTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF

Kinase 26010.AA TyrKc 40-275 20 4.8e-12 -27.97 SMART 1-280 (280) Show / Hide
Range on Protein: 40-275
Range on HMM: 1-280/280
Sequence Identity: 20% (60 aa)

FELLNVIGEGKFGTVLLVKKKDSGKLFAMKIIKKSIIRKRQFAHRIIQEKDILAFCN-NNFMTKL-----------HYSFQNQ------NNLFLILDYCS
 .|. ..||| ||.| . . |      | | .|..                . .|..  . |.||            .  | .        |.... |..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMP

GGDLFNYI-SKKNTISEKDAKFYAAQIVLMLEYLHSQNIVYRDLKPENILIEKNGYLKLGDFGYARQNMDS------IEAKSV----CGTP----HYFPP
.||| .|. ....... ||   .. ||    |||||.|.. |||   |.|. .|.  | .||| .|   |        . ...    .|         .|
HGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP

EMITREG-HGKPVDWWALGCVIYEMV-FGATPFDD-----SNQKILFDRIKNS--PVIFEND-------KNKKVSN--------------NFKDIVNKL
| | ..|      | |. | ...|.  .|..|  .      . . .. ..|.   . . .||         ... .              .|..|. ..
ECI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase 26010.AA S_TK_X 299-363 23 3.2e-09 37.86 SMART 1-79 (79) Show / Hide
Range on Protein: 299-363
Range on HMM: 1-79/79
Sequence Identity: 23% (21 aa)

DKMDWTALSN--QTIAAPFIPAVK----KVSDVSNFDITFTNKDVSDYNNDSTDCSSDDDS-----------------DEYQNFYYDC
.. || .| |  ..| .||.| .|       |.||||  ||.....          ..||.                 |.. .| |..
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM---------LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF

Kinase 26010.AA Pkinase_Tyr 111-183 35 0.00018 15.77 Pfam 80-156 (270) Show / Hide
Range on Protein: 111-183
Range on HMM: 80-156/270
Sequence Identity: 35% (27 aa)

NNLFLILDYCSGGDLFNYISK----KNTISEKDAKFYAAQIVLMLEYLHSQNIVYRDLKPENILIEKNGYLKLGDFG
|...... |. .||| .|  |    |. .. ||   ...||   .|||.|.|.. |||   |.|...|.  | .|||
NQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG

Kinase 26010.AA Pkinase_Tyr 40-54 40 0.184464 5.57 Pfam 1-15 (270) Show / Hide
Range on Protein: 40-54
Range on HMM: 1-15/270
Sequence Identity: 40% (6 aa)

FELLNVIGEGKFGTV
 ... ..||| ||.|
ITFGKKLGEGAFGEV