Gene 2547 (Tetrahymena)

2547

Species: Tetrahymena
Alias: TTHERM_00248510, PreTt02547, 2547, 823, 21.m00378
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
2547.AA Protein None 397 None Fasta, JSON
2547.kin_dom Protein Kinase Domain None 254 None Fasta, JSON
2547.NA RNA None 1194 None Fasta, JSON

Protein domain

Protein domains of 2547.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 2547.AA SGK 72-325 56 1.2e-200 625.99 In-house 1-283 (283) Show / Hide 
Range on Protein: 72-325
Range on HMM: 1-283/283
Sequence Identity: 56% (159 aa)

FEILKVIGEGSFGKVFMVQKKDD------------------GKIYAMKQLRKSNLT--------KQHQKLKTIEEKNIMVNMKSPFIVQLKYAFQTTTKL
|..|||||.||||||..|..|||                  .|.|||| |.|            | .||....|...|..|||.||||.|.|||||..||
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YFVMDFMQGGEMFYHIRKAKYFKEDVARFYVSELVLALEYLHSKDTIYRDLKPENILLGADGHIKICDFGLSKQGVKDSDKTKTICGTPEYLAPEILLGQ
|||||...|||||||....|.|.||.||||..|.|.|||||||.|.||||||||||||...||....||||.|.|.|..|.|.|.||||||||||.|..|
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

PHGKEVDWYSLGCVLYEFLSGAPPFYSRDKQQMYQQRINSDIQRKPQFQNDAWDLIQLLLAKNPKDRLNTA---AQVKSHPFF
||...|||..|||||||...|.||||||.|||||...||...|..||..||||||||.||.|.||.||.|.   ...|.||||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 2547.AA AGC 72-325 34 6.00000000001e-185 483.36 In-house 1-395 (395) Show / Hide 
Range on Protein: 72-325
Range on HMM: 1-395/395
Sequence Identity: 34% (138 aa)

FEILKVIGEGSFGKVFMVQKK------DDGKIYAMKQLRKSN---LTKQHQKLKTIEE------------KNIMVNMK----------SPFIVQ-LKYAF
||.|||||.||||||. |.||      | ||.|||| |.|.    ..|...  .|. |            .||.....          .||||. |.|.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTTTK--LYFVMDFMQ---------GG-EMFYHIR---KAKYFKEDVARFYVSE-------LVLALEYLHS-KDTIYRD-LKPENILLGADGHIKICDFG
|. ..  |||||..|.         || |.|.|..   | ..| |..|||| .|       .||||||||| .. |.|| |||||||| .|||||..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSKQGVKDS--------------------------------------------------DKTKTICG--TPEYLAPEILLGQPHGKEVDWYS--LGCVLY
|.|.|..|                                                   |.|.|.||  ||||.|||||    .||..||.|  |||..|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EFLSGAPPFYSR----------DKQQMYQQRI------NSDIQRK----------PQFQNDAWDLIQLLLAKNPKDRLNT---------AAQVKSHPFF
|.|.| ||||.           .. .|.|. .      | ...            ..| ..|.|||. || |.|..|| .         | ..|.||.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 2547.AA Akt 72-325 53 1.5e-165 533.23 In-house 1-264 (264) Show / Hide 
Range on Protein: 72-325
Range on HMM: 1-264/264
Sequence Identity: 53% (141 aa)

FEILKVIGEGSFGKVFMVQKKDDGKIY-AMKQLRKSNLTKQHQKLKTIEEKNIMVNMKSPFIVQLKYAFQTTTKLYFVMDFMQGGEMFYHIRKAKYFKED
|..|||.| ||||||| |.|||..|.| ||| |.|. . .. |.  |. |.|| .....||||.|.|.||| .|||||||...||| |||......|.||
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

VARFYVSELVLALEYLHSKDTIYRD-LKPENILLGADGHIKICDFGLSKQG-VKDSDKTKTICGTPEYLAPEILLGQPHGKEVDWYS-LGCVLYEFLSGA
 ||||..|..||.|.||||. |||| |||||||. .||||...||||.|.. .|| |||||.||||||||||||.|. |.| |||.. ||||.||.. |.
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

PPFYSRDKQQMYQQRINSDIQRK--PQFQNDAWDLIQLLLAKNPKDRL----NTAAQVKSHPFF
||||..|..||...  |.... .  ....... |||  || |.|| ||    |.| ..|.||.|
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 2547.AA AktR 72-325 47 2e-138 466.2 In-house 1-268 (268) Show / Hide 
Range on Protein: 72-325
Range on HMM: 1-268/268
Sequence Identity: 47% (127 aa)

FEILKVIGEGSFGKVFMVQKK-DDGKIYAMKQLRKSNLTKQHQKLKTIEEKNIMV-NMKSPFIVQLKYAFQTTTKLYFVMDFMQGGEMFYHIRKAKYFKE
|...|..|.| ||||..|||| |..|.|||| ..|... .. |.  || |.|||   .. ||||.|.|.||| .||.|.|....|||.|.|..| | |.|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

DVARFYVSELVLALEYLHSK-DTIYRDLKPENILLGADGHIKICDFGLSK-QGVK-DSDKTKTICGTPEYLAPEILLG-QPHGKEVDWYSLGCVLYEFLS
..|||| .. .|||||||.. . ||||||||||||. |||.|| |||||| |... ...|....||||||.|||...  ..|.| |||...|...|| ..
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GAPPFYSRDKQQMYQQRINSD---IQRKPQFQNDAWDLIQ-LLLAKNPKDRL----NTAAQVKSHPFF
| ||||. ...||.|  ....   ..  ..| . . ||||  || |||. ||    |.. ..||||.|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 2547.AA PKA 72-325 46 7.1e-118 397.9 In-house 1-263 (263) Show / Hide 
Range on Protein: 72-325
Range on HMM: 1-263/263
Sequence Identity: 46% (123 aa)

FEILKVIGEGSFGKVFMVQKKDDGKIYAMKQLRKSNLTKQHQKLKTIEEKNIMVNMKSPFIV-QLKYAFQTTTKLYFVMDFMQGGEMFYHIRKAKYFKED
|||....| ||||.|  ...|..|..||||.|.|.   .  |.  .. ||||. |.|.|||| .... ||. ..||.||.. .|||||...|| . | ..
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

VARFYVS-ELVLALEYLHSKDTIYRDLKPENILLGADGHIKICDFGLSKQGVKDSDKTKTICGTPEYLAPEILLGQ-PHGKEVDWYSLGCVLYEFLSGAP
.|.||.  . |||||||||.. |||||||||||.  .||||| ||| .|  |.|   |.|.|||||||||||...  .||| ||| .||.. ||.|.| |
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKK-VDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYP

PFYSR--DKQQMYQQRINSDIQRKPQFQNDA---WDLIQLLLAKNPKDRL----NTAAQVKSHPFF
|||    |. |.|.  .| .|.  ..| .||    |||  ||..... |.    | . ..| |..|
PFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 2547.AA RSK 75-325 43 9.69999999999e-115 387.49 In-house 1-278 (278) Show / Hide 
Range on Protein: 75-325
Range on HMM: 1-278/278
Sequence Identity: 43% (122 aa)

LKVIGEGSFGKVFMVQKK---DDGKIYAMKQLRKSNLTKQHQK--LKTIEEKNIMVNMK-SPFIVQLKYAFQTTTKLYFVMDFMQGGEMFYHIRKAKY--
||| |.|..|||| ..|.   | |.|||||.|.|. . .|.||    | .| ||.   . .||||.|.||||| .||| .|... |||.|.|..| |.  
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKI-VQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFG

-FKEDVARFYVSELVLALEYLHSKDTIYRDLKPENILLGA---DGHIKICDFGLSKQGVKD-SDKTKTICGTPEYLAPEILL---GQP-HGKEVDWYSLG
 | || |.|| .|.|||.|.||... |.|||||||||.     .||||..|||..||.. | . .|.| |.| ||.|||.|    .|  |.| .||.|||
CFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

CVLYEFLSGAPPFYS-RD-KQQMYQQRINSDI--QRKP---QFQNDAWDLIQLLLAKNPKDRLNT----AAQVKSHPFF
...|| |.|.|||.. .|  ..   .|| .    .. |      ..| |||. .| ..|..||.     |...|.||.|
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 2547.AA S_TKc 72-325 38 1.9e-106 360.87 SMART 1-231 (231) Show / Hide 
Range on Protein: 72-325
Range on HMM: 1-231/231
Sequence Identity: 38% (104 aa)

FEILKVIGEGSFGKVFMVQKKDDGKIYAMKQLRKSNLTKQHQKLKTIEEKNIMVNMKSPFIVQLKYAFQTTTKLYFVMDFMQG--GEMFYHIRKAKY---
.|||..||.|.||||. ...|..|.|.|.|...           ... | .|. . . |.||.|...||. ..||.||... |  |..| .|.| ..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FKEDVARFYVSELVLALEYLHSKDTIYRDLKPENILLGADGHIKICDFGLSKQGVKDSDKTKTICGTPEYLAPEILLGQPHGK-EVDWYSLGCVLYE
   | | .||||. ....||||.||.  |.||||||||||    |||||||||..|        .|.||||.|.|||.|   ..|| ..||.|.||.|||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

FLSGAPPFYSRDKQQMYQQRINSDIQRKPQFQNDAWDLIQLLLAKNPKDRLNTAAQVKS-------HPFF
.|.| |||.  . |.|...              .|.|.|. .| |.|..|. || ..         ||.|
MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRP-TA-EALQDEWDIKCHPWF
Kinase 2547.AA p70 72-325 38 2.9e-105 356.0 In-house 1-299 (299) Show / Hide 
Range on Protein: 72-325
Range on HMM: 1-299/299
Sequence Identity: 38% (118 aa)

FEILKVIGEGSFGKVFMVQKKD---DGKIYAMKQLRKSNLTK-----QHQK---------------------LKTIEEKNIMVNMKSPFIVQLKYAFQTT
|| |||.|.| .|||| | |      |||||||.|||   .      .| .                      .|  | ||    |.|||. | ||||| 
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN

TKLYFVMDFMQGGEMFYHIRKAKYFKEDVARFYVSELVLALEYLHSKDTIYRDLKPENILLGADGHIKICDFGLSKQGVKDSDK----------TKTICG
 ||| . ... ||| |.|  .   . ||.|.|| || ..|||.||... |||||||||..| . ||..  ||||.|. ..|. .          | |.||
GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG

TPEYLAPEILLGQPHGKEVDWYSLGCVLYEFLSGAPPFYSRDKQQMYQQRINSDIQRK------PQFQNDAWDLIQLLLAKNPKDRLN----TAAQVKSH
|.|| |||||..  |...|||.|||| .|  | |.|||    ...     |.. .. |      |   ... |||. || ..|. |..     ||....|
TIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKT----IDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEH

PFF
|||
PFF
Kinase 2547.AA RSK 72-325 37 5.1e-103 348.54 In-house 1-271 (271) Show / Hide 
Range on Protein: 72-325
Range on HMM: 1-271/271
Sequence Identity: 37% (102 aa)

FEILKVIGEGSFGKVFMVQKK---DDGKIYAMKQLRKSNLTKQHQKLKTIEEKNIMVNMKSPFIVQLKYAFQTTTKLYFVMDFMQGGEMFYHIRKAKYFK
.|....||.|||.||. ..|.   | .. |||| ..|. .    .  .. || .|. .  .||||.|.|.||. .|.| .||||.||..| .. | |.| 
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFS

EDVARFYVSELVLALEYLHSKDTIYRDLKPENILLGAD----GHIKICDFGLSKQGVKDSDK-TKTICGTPEYLAPEILLGQPHGKEVDWYSLGCVLYEF
|. ..|| .|. ||.|||||.. ..|||||||||. ..    |||||||||..|| ..| .. ..| |.| .|.|||.|  | |.. .||.|.| ..|| 
EREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQ-LRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEM

LSGAPPFYSRDKQQMYQQRINSDIQR-------KPQFQNDAWDLIQLLLAKNPKDRLNT----AAQVKSHPFF
|.|..||...... . ..  . .  .       .      | ||.  .|  .|  || .    ..|.|.||.|
LTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase 2547.AA Ciliate-E2-Unclassified 72-325 30 5.5e-100 338.48 In-house 1-352 (352) Show / Hide 
Range on Protein: 72-325
Range on HMM: 1-352/352
Sequence Identity: 30% (108 aa)

FEILKVIGEGSFGKVFMVQKKDDGKIYAMKQLRKSNLTKQHQKLK---------TIEEKN-------------IMVNMKSPFIVQLKYAFQTTTKLYFVM
..|.|.||.|.||||...|.|.....||||.. |..  ||.|...         ....|.             |..|...|||| . |.||.. ..|.||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

DFMQGGEMFYHIRK-----------------AKYFKEDVAR-----FYVSELVLALEYLHSKD-TIYRDLKPENILLGADG---HIKICDFGLSK-----
....||.....|.|                  | | |  |.     ||  .....|||||.|   |.||.||||||.  .|   .|||.|||.||     
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

----------QGVKDSDKTKTICGTPEYL----APEILLGQPHG----KEVDWYSLGCVLYEFLSGAPPFYSRDKQQ----------------MYQQRIN
          ... ......|.||||.|.    |||.| || ..    ...|..|||..|||.| | .|||.... |                .||. ..
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

SDIQRKP--------QFQNDAWDLIQ----LLLAKNPKDRLNTAAQVKSHPFF
 .|| ..        . .. |.|.|.     .| |||. |. |. |.. ||.|
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRI-TFEQILNHPWF
Kinase 2547.AA Pkinase 72-325 34 2.6e-96 331.06 Pfam 1-293 (293) Show / Hide 
Range on Protein: 72-325
Range on HMM: 1-293/293
Sequence Identity: 34% (101 aa)

FEILKVIGEGSFGKVFMVQKKDDGKIYAMKQLRKSNLTKQHQKLKTI-EEKNIMVNMKSPFIVQLKYAFQTTTKLYFVMDFMQGG----EMFYHIR--KA
..|...||.||||.|.  ..|..|||.|.|...|..  .. .. ..   |  || ....|.||.|...|.. ...|.||....||    . | .|.  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KYF--KEDVARFYVSELVLALEYLHSKDTIYRDLKPENILLGADGHI----KICDFGLSKQG-VKDSDKTKTICGTPEYLAPEILL-GQPHGKEVDWYSL
. |   |....||. ... .|||.||.  |.|||||||||.  .|||    |||||||.||     .  ..|.||||.|.|||... ||..|..||..|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCVLYEFLSGAPPFYSR------DKQQMYQQRINSDIQRKPQFQ---------------------NDAWDLIQLLLAKNPKDRLNTAAQVKSHPFF
||.|||.|.| |||...      |..||....   .. .  .                        .. |.|  .|.|.||.|.. |.|.. ||.|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-AEQILQHPWF
Kinase 2547.AA MAST 72-218 42 1.7e-63 203.46 In-house 1-147 (334) Show / Hide 
Range on Protein: 72-218
Range on HMM: 1-147/334
Sequence Identity: 42% (62 aa)

FEILKVIGEGSFGKVFMVQKKDDGKIYAMKQLRKSNLTKQHQKLKTIEEKNIMVNMKSPFIVQLKYAFQTTTKLYFVMDFMQGGEMFYHIRKAKYFKEDV
||. |.|. | .|||. | .|. ....||| ..||.. . ..    . |.||  . ..||.| . |.|||...|..||..|.||  . ...   || |. 
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

ARFYVSELVLALEYLHSKDTIYRDLKPENILLGADGHIKICDFGLSK
|..|..|.||.||||||.. . |||||.|.|. ..||||. ||||||
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSK
Kinase 2547.AA MAST 226-325 40 5.2e-41 129.74 In-house 220-334 (334) Show / Hide 
Range on Protein: 226-325
Range on HMM: 220-334/334
Sequence Identity: 40% (46 aa)

KTKTICGTPEYLAPEILLGQP-HGKEVDWYSLGCVLYEFLSGAPPFYSRDKQQMYQQRINSD---IQRKPQ--------FQNDAWDLIQLLLAKNPKDRL
. | .||||.|.|||..|||. ||| ||| |.| ..|||| | |||   . .  .|. .| .   |   .         .. .| |||. ||. .|..||
QNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRL

NTA---AQVKSHPFF
 .    ..||.||||
GANNGADEVKQHPFF
Kinase 2547.AA TyrKc 72-325 22 4.3e-14 5.25 SMART 1-280 (280) Show / Hide 
Range on Protein: 72-325
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

FEILKVIGEGSFGKVFMVQKKDDGKIYAMKQLRKSNLTKQHQKLKTIEEKNIMVNM--KSPFIVQLKYAFQTT-------TKLYFVMDFMQGGEMFYHIR
 . .|..||| ||.|.  . |      | | |...       .   ..| .|| .   . | ||.|  .  .          |. || .| .|    ..|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KAKY-FKEDVARFYVSELVLALEYLHSKDTIYRDLKPENILLGADGHIKICDFGLSKQGVKD-------SDKTK--TICGTP----EYLAPEILLGQPHG
| .  .. .    .        ||||||  | |||   |.|.|.....||.|||||. .  |       . ..|  . .|        .||| .      
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

KEVDWYSLGCVLYEFLS-GAPPFYS-----RDKQQMYQQRINSDIQRKPQF---------QNDAWDLIQLLLAKNPKDRLNTAAQVKSHPFF
 . | .| | ...| .. |..| .       . |.....  . .  ..|.            .  ....   . .|.||  | ...  | .|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRP-TFSEI--HECF
Kinase 2547.AA S_TK_X 326-390 26 4.4e-11 44.08 SMART 1-79 (79) Show / Hide 
Range on Protein: 326-390
Range on HMM: 1-79/79
Sequence Identity: 26% (22 aa)

KTVDWEKLLN--KDVRPPFVLKFN----NEQDTRYISNEFVKQAVQNTPYTPNVGGLAGGNQD-----------FDGFTYQG
. .||.||.|  | . |||. | .    ...||..   || ....    .||   .| ....            | ||||  
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM---LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 2547.AA Pkinase_C 345-392 25 4.5e-07 28.2 Pfam 1-46 (46) Show / Hide 
Range on Protein: 345-392
Range on HMM: 1-46/46
Sequence Identity: 25% (12 aa)

KFNNEQDTRYISNEFVKQAVQNTPYTPNVGGLAGGNQDFDGFTYQGGV
. ... ||..   || ..... ||  ..    .| .  | ||||    
QVKSPTDTSNFDPEFTDEPPMDTP-PDWR-MSSGDQEPFRGFTYVNPD
Kinase 2547.AA Pkinase_Tyr 200-234 29 4.9e-05 17.68 Pfam 141-177 (270) Show / Hide 
Range on Protein: 200-234
Range on HMM: 141-177/270
Sequence Identity: 29% (11 aa)

NILLGADGHIKICDFGLSKQG-VKDSD-KTKTICGTP
|.|.. ....|||||||..    .|   .... .  |
NCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLP
Kinase 2547.AA Pkinase_Tyr 72-155 25 0.000279 15.12 Pfam 1-92 (270) Show / Hide 
Range on Protein: 72-155
Range on HMM: 1-92/270
Sequence Identity: 25% (24 aa)

FEILKVIGEGSFGKVFMVQKK----DDGKIYAMKQLRKSNLTKQHQ--KLKTIEEKNIMVNM-KSPFIVQLKYAFQ-TTTK--LYFVMDFMQGG
 ...|..|||.||.|..   |    ...   | | |.    . ..|  . . ..| .|| .. . | ||.|  .         .| || .|..|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHG
Kinase 2547.AA Pkinase_Tyr 254-281 20 7.653163 0.09 Pfam 198-227 (270) Show / Hide 
Range on Protein: 254-281
Range on HMM: 198-227/270
Sequence Identity: 20% (6 aa)

YSLGCVLYEFLS-GAPP-FYSRDKQQMYQQ
.| | ...| .. |. | ..  . ...|..
WSFGVLMWEIFTYGEQPTYPGMSNEEVYEY