Gene 11728 (Tetrahymena)

11728

Species: Tetrahymena
Alias: PreTt11728, 1.m00776, 938, TTHERM_00011220, 11728
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CAMK
Family: CAMK1

Sequence

Name Sequence Type Origin Length Description Download
11728.AA Protein None 384 None Fasta, JSON
11728.NA RNA None 1155 None Fasta, JSON
11728.kin_dom Protein Kinase Domain None 257 None Fasta, JSON

Protein domain

Protein domains of 11728.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 11728.AA CAMK1 82-338 53 7.89999999999e-208 610.31 In-house 1-276 (276) Show / Hide 
Range on Protein: 82-338
Range on HMM: 1-276/276
Sequence Identity: 53% (149 aa)

FKFDKVLGEGSFAVVHKCIRKEN---NEEVAVKVID-KANLEHDDQ---LALETECEIMAN---IDHPNIVKCTCVYDEKSKFYMVMELMTGGELFDRIV
..|.|..|.|.|..|..|..||.   ....|.|.|| | .....|.    |||.|.||| .   ||||||.|. ..|.....||.||||.||||||||||
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

EKEFYSEKEACDVIKPIVDAINYCHKMGIAHRDLKPENLLYTSPDPDATIK--ISDFGLAKVIS-DE-LMTTACGTPSYIAPEILEG---KGYTFAVDYW
||..|.||.|....|.|..|..|.|..||.||||||||||| ..|.|..||  |.||||.| .. || ||.||||||.|.|||.||.   |.|  |.|.|
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMW

SIGVILYVLLCGFPPFYEDT-NEKLFAMIKKGQFEFPSPQWDPISNQ-AKDLIKNLLKVDPKQRYNAEQILNHAWI
|||||.|.||||.||||... ...||..|||...|||||.|| ||.| |||.||..|.||||.||..||.||| ||
SIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase 11728.AA CAMK 87-338 29 7.6e-139 450.39 In-house 1-425 (425) Show / Hide 
Range on Protein: 87-338
Range on HMM: 1-425/425
Sequence Identity: 29% (125 aa)

VLGEGSFAVVHKCIRKENN------------EEVAVKVIDKANLE--------------------------HDDQLALETECEIMAN-------IDHPNI
.||.|||..|..||.|...            ..||.|.|||  |                             |.  .. | ||| .       .|||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKCTCVYDE-------------------KSKFYMVM---ELMTGGEL----FDRIVEKEF---------------YSEKEACDVIKPIVDAINYCHKMGI
.|.  ||.                    ....||||   |...||||    ||.|||..                ..|.||. ... |..|..|||...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHRDLKPENLLYTSPDPD--------------ATIKISDFGLAKVIS-------------------------DELMTTACGTPSYIA-PEILEG------
.||||||||.|... ..|              ..|||.|||.|...                          ...|.| ||||.|.| ||.|.|      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------KGYTFAVDYWSIGVILYVLLCGFPPFYED-------------TNEKLFAMIKKGQFEFPSPQ------------WDPISNQ--------AKD
        ..|....| ||.|||||..|||.||||.|             . ..|| .|.||...||.|.            || ||..        .||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LIKNLLKVDPKQRYNAEQILNHAWI
||...|.|||..|...||.||| |.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 11728.AA RAD53 82-338 38 2.4e-133 399.75 In-house 1-305 (305) Show / Hide 
Range on Protein: 82-338
Range on HMM: 1-305/305
Sequence Identity: 38% (118 aa)

FKFDKVLGEGSFAVVHKCIRKENNEEVAVKVIDK---A---NLEHDDQLALETECEIMANIDHPNIVKCTCVYDEK-SKFYMVMELMTGGELFDRIV-EK
. ..|.|| | |..| ....|.. . ||.| |||   .   . . ..   ...| ||. .. ||.|..   ..|..   .|||.|||||||||..||  |
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

EF---YSEKEACDVIKPIVDAINYCHKMGIAHRDLKPENLLYTSPDPDA---------------TIKISDFGLAKVISDE-LMTTACGTPSYIAPEILEG
 .   ..| .. .  . ..||..| | .||.|||||||| |. ..| .                 |||.||||.|....  .|.| ||||.| |||.. .
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVITS

K---------------GYTFAVDYWSIGVILYVLLCGFPPFYED-TN----EKLFAMIKK-GQFEFPSPQWDPISNQAKDLIKNLLKVDPKQRYNAEQIL
|               ||| .|| ||.|.|||..|||.||| .| |      .||  ||. | ..||.|.|| ||. ||||||..|.|||. ||.....|
KGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEAL

NHAWI
|| |.
NHPWM
Kinase 11728.AA CDPK 82-338 44 7e-128 394.21 In-house 1-271 (271) Show / Hide 
Range on Protein: 82-338
Range on HMM: 1-271/271
Sequence Identity: 44% (121 aa)

FKFDKVLGEGSFAVVHKCIRK-ENNEEV-AVKVIDKANLEHDDQ-LALETECEIMANIDHPNIVKCTCVYDEKSKFYMVME--LMTGGELFDRIVEKEFY
.|. ||||.|.| .| |.. |  .|.|  |.|.| | .. . .|   .  | ||. ..|||||.|   .|  .  .| |||  . |||||||.|.||  .
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF

SEKEACDVIKPIVDAINYCHKMGIAHRDLKPENLLYTSPDPDA----TIKISDFGLAKVISD------ELMTTACGTPSYIAPEILEGKGYTFAVDYWSI
.||||..... |. |.||||. .| ||||||||.|..| ..|.    .||. |.|..|          . |.. |||| |||||.|..| |   .| ||.
TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCDIWSC

GVILYVLLCGFPPFYEDTNEKLFAMIKKGQFEFPSPQWDPISNQAKDLIKNLLKVDPKQRYNAEQILNHAWI
|||||.|||| |||| .. .. ....|||...|  |.|| ||..|||||...| .|||.|. |.|.|.| |.
GVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase 11728.AA Ciliate-E2a 82-338 38 5.1e-115 340.0 In-house 1-275 (275) Show / Hide 
Range on Protein: 82-338
Range on HMM: 1-275/275
Sequence Identity: 38% (106 aa)

FKFDKVLGEGSFAVVHKCIRKENNEE-VAVKVIDKANLEHDDQLALETECEIMANIDHPNIVKCTCVYDEKSKFYMVMELMTGGELFDRIVEKE-FYSE-
.|| |..|.|.|..| .  .|..... ...|.|.|.. ..... ... |  || ..||||| |   ||  .. .|.|||.  ||||.|.|...  | .| 
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEI

KEACDVIKPIV-DAINYCHKMGIAHRDLKPENLLYT--SPD--PDATIKISDFGLAKVISDEL---MTTACGTPSYIA------PEILEGKGYTFAVDYW
.|.||... .  ....|.|. .| ||||||||.|..  |..  ... |||.|||||. |..     | . |||| |.|      .|.|..| |.  .| |
QEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDMW

SIGVILYVLLCGFPPFYEDTNEKLFAMIKKGQFEFPSPQ-WDPISNQAKDLIKNLLKVDPKQRYNAEQILNHAWI
|.|||.| |||| |||.  | .  . ..|| .. | .|. |  .|...|||.| .|..|||.|..|.|.||| | 
SCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 11728.AA MAPKAPK 85-338 37 5.4e-114 354.41 In-house 4-292 (292) Show / Hide 
Range on Protein: 85-338
Range on HMM: 4-292/292
Sequence Identity: 37% (110 aa)

DKVLGEGSFAVVHKCIRKENNEEVAVKVIDKANLEHDDQLAL-ETECEIMANIDHPNIVKCTCVYDE----KSKFYMVMELMTGGELFDRIVE--KEFYS
..|||||. . | .|  |  ..| |||....    |  | |. | |   ... .|||||.   .. .    ...||.|||.| |||||..| .  .  ..
KEVLGEGIYGKVQTCVHKRTGQEYAVKILEDQ-PGHSRQKARREVELHWHCQ-GHPNIVQIIDWFENMYQFDKCFYLVMECMEGGELFQHIQQRGHKHFT

EKEACDVIKPIVDAINYCHKMGIAHRDLKPENLLYTSPDPDATIKISDFGLAKV------ISDE----LMTTACGTPSYIAPEILEGKG----YTFAVDY
|.||  ..| |  |. ..|.|.||||||||||.|.|........|..|||.||.      ....     ..|.|.|| |.|||...       |    | 
EREASQIMKDICSAVDFLHSMNIAHRDLKPENILCTDTNHNCPVKLCDFGFAKEIHLNHDCTTPITTPELMTPCYTPYYMAPEVVGAFKEAHTYDKSCDM

WSIGVILYVLLCGFPPFYEDTN----------------EKLFAMIKKGQFEFPSPQWDPISNQAKDLIKNLLKVDPKQRYNAEQILNHAWI
||.|||.|..|||.|||| ..                 ...|. |..||.|||.. |. ||..|||||..||..||.||. .||..|| ||
WSLGVIMYIMLCGYPPFYSNCGDEDCSWDRGEACRDCQNMMFHRIQEGQYEFPDEEWSHISEEAKDLIRKLLRRDPTQRLTIEQVMNHPWI
Kinase 11728.AA DCAMKL 82-338 41 1.4e-113 354.87 In-house 1-279 (279) Show / Hide 
Range on Protein: 82-338
Range on HMM: 1-279/279
Sequence Identity: 41% (116 aa)

FKFDKVLGEGSFAVVHKCIRKENN-EEVAVKV-----------------IDKANLEHDDQLALETECEIMANIDHPNIVKCTCVYDEKSKFYMVMELMTG
..  .. | | |||||.|...|.. .. | |.                 |||...     .  . | .||  |.||.|..   ..| . . |.|||. .|
YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKGKEHM-IDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVMEYVQG

GELFDRIVEKEFYSEKEACDVIKPIVDAINYCHKMGIAHRDLKPENLLYTS-PDPDATIKISDFGLAKVISD--ELMTTACGTPSYIAPEILEGKGYTFA
| ||| |.|   ..|..|   .  .  |..| | |.| |||.||||||    .|   ..|  |||||... .   .. | |||| |.|||||  .||   
GDLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILMETGYGCK

VDYWSIGVILYVLLCGFPPFYED--TNEKLFAMIKKGQFEFPSPQWDPISNQAKDLIKNLLKVDPKQRYNAEQILNHAWI
|| |..|||||.||||||||       |.||  |  |.||||.| || || .|||||...|.|||..|| ||||. | |.
VDIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase 11728.AA CAMKL 82-338 34 3.3e-112 359.43 In-house 1-297 (297) Show / Hide 
Range on Protein: 82-338
Range on HMM: 1-297/297
Sequence Identity: 34% (105 aa)

FKFDKVLGEGSFAVVHKCIR-KENNEEVAVKVIDKANLEHDDQLA-------------LETECEIMANID---HPNIVKCTCVYDEKSK------FYMVM
... |.||.|||..|  ..  . ..|.||.|.|||  .  |..               .. | .||  ..   ||||.|   |.. ...      .|.||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELMTGGE--LFDRIVEKEF----YSEKEACDVIKPIVDAINYCHKMGIAHRDLKPENLLYTSPDPDATIKISDFGLAKVIS------DELMTTACGTPSY
|.  |||  |||.||...      .|.||.   . ||.|.||||..||.|||.||||.| .. .   .|||.|||..  .       .....| ||.|.|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

IAPEILEG--KGYT-FAVDYWSIGVILYVLLCGFPPFYEDTN------EKLFAMIKKGQFEFPSPQWDPISNQAKDLIKNLLKVDPKQRYNAEQILNHAW
 ||||..|  | |  ..|| ||.|||||...||  || .||.       .   . |. .  .  | |  .| ...|||. .|.|.|..|....||.|| |
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

I
 
M
Kinase 11728.AA S_TKc 82-338 35 8.60000000001e-108 365.33 SMART 1-231 (231) Show / Hide 
Range on Protein: 82-338
Range on HMM: 1-231/231
Sequence Identity: 35% (98 aa)

FKFDKVLGEGSFAVVHKCIRKENNEEVAVKVIDKANLEHDDQLALETECEIMANIDHPNIVKCTCVYDEKSKFYMVMELMTG--GELFDRIVEKEF----
... ...|.|.|..|.||. |. ...||.|.|.           .. | .|. . .||||||.  |... ...|||||.. |  |.|||.|...      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--YSEKEACDVIKPIVDAINYCHKMGIAHRDLKPENLLYTSPDPDATIKISDFGLAKVISDELMTTACGTPSYIAPEILEGKGYTF-AVDYWSIGVILYV
  ..| .|. ... |..|..|||..|| ||||||||.| ..     .|||.|||||...     || |||| |.|||.|   ||.. ..| ||.|.||| 
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

LLCGFPPFYEDTNEKLFAMIKKGQFEFPSPQWDPISNQAKDLIKNLLKVDPKQRYNAEQILN-------HAWI
.||| |||.  . ...| .|.              | .|||.|...|..||..|. | ..|.       | |.
MLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 11728.AA Pkinase 82-338 38 1.9e-106 364.71 Pfam 1-293 (293) Show / Hide 
Range on Protein: 82-338
Range on HMM: 1-293/293
Sequence Identity: 38% (114 aa)

FKFDKVLGEGSFAVVHKCIRKENNEEVAVKVIDKANLEH-DDQLALE-TECEIMANIDHPNIVKCTCVYDEKSKFYMVMELMTGG----ELFDRIV--EK
... ...|.|||..| ||..| ....||||.|.| . ..  || ..  .|..||....|||||.. ... .|.. |||||.. ||    .|||.|   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

EFY--SEKEACDVIKPIVDAINYCHKMGIAHRDLKPENLLYT-SPDPDATIKISDFGLAK---VISDELMTTACGTPSYIAPEILE-GKGYTFAVDYWSI
  .  ||.|...... |. ...|||.||| ||||||||.|.   ...||..||.||||||     ... ||| |||| |.|||..  |..|. .|| ||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVILYVLLCGFPPFYED------TNEKLFAMIKKGQFEFPSPQWDPIS-----------------NQAKDLIKNLLKVDPKQRYNAEQILNHAWI
|.||| .||| |||...      .  .....|......|..|.|..||                   .||.||..|..|||.|..|||||.| |.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 11728.AA RSK 82-338 38 1.5e-102 347.02 In-house 1-271 (271) Show / Hide 
Range on Protein: 82-338
Range on HMM: 1-271/271
Sequence Identity: 38% (104 aa)

FKFDKVLGEGSFA---VVHKCIRKENNEEVAVKVIDKANLEHDDQLALETECEIMANIDHPNIVKCTCVYDEKSKFYMVMELMTGGELFDRIVEKEFYSE
. . ...|.|||    |..||..| .| . |.|.|.|| .   |.   |.|  |.....||.|||   |..   | ||.|..| ||.||||.. . . ||
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDRVCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFSE

KEACDVIKPIVDAINYCHKMGIAHRDLKPENLLYTSP--DPDATIKISDFGLAKVI--SDELMTTACGTPSYIAPEILEGKGYTFAVDYWSIGVILYVLL
.|....   |  | .| |. ||.|||||||| || .   .|. .||| |||.||     ...  | |.|  |.|||.|  .|.. |.|.|| ||..|  |
REVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPG-HIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEML

CGFPPFYEDTNEKLFAMIKK---GQFEFPSPQWDPISNQAKDLIKNLLKVDPKQRYNA-----EQILNHAWI
 |..||.. ... ....|..   |.| . .. || ||  ||||.  .|..|| .|. |     |||..|.|.
TGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase 11728.AA RSK 86-338 35 5.2e-101 341.88 In-house 2-278 (278) Show / Hide 
Range on Protein: 86-338
Range on HMM: 2-278/278
Sequence Identity: 35% (99 aa)

KVL---GEGSFAVVHKCIRKENNEEVAVKVIDKANLEHD--DQLALETECEIMANID-HPNIVKCTCVYDEKSKFYMVMELMTGGELFDRIVEKEF---Y
|||   | |.. ...||... .. . |.||..|| .     |.    || .|.. .  ||.||.   ......|.|..||.. |||||... ....    
KVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCF

SEKEACDVIKPIVDAINYCHKMGIAHRDLKPENLLYTSPDPD-ATIKISDFGLAKV-ISD--ELMTTACGTPSYIAPEILE----GKGYTFAVDYWSIGV
||.|||...  || |. . |. || |||||||| ||.. . . ..||..|||..|    |  ... | |.|  |.|||.|     ..|.. |.|.|| ||
SEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

ILYVLLCGFPPFYE---DTNEKLFAMIKKGQFEFPSPQWDPISNQAKDLIKNLLKVDPKQRYN-----AEQILNHAWI
..| .| |.|||.    .. ..... |.||.| ...| |. .|. |||||. .|..||..|..     ||.|..|.|.
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 11728.AA Pkinase_Tyr 82-296 29 1.9e-30 103.71 Pfam 1-233 (270) Show / Hide 
Range on Protein: 82-296
Range on HMM: 1-233/270
Sequence Identity: 29% (69 aa)

FKFDKVLGEGSFAVVHKCIRK----ENNEEVAVKVIDKANLEHDD--QLALETECEIMANI-DHPNIVKCT-CVYDEKSK--FYMVMELMTGGELFDRIV
 .|.|.||||.| .|.|.. |    ... .||||.. | .  |..  . ..  | .|| .. .|||||..  ...|..     |.|||.| .| | |   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

E----KEFYSEKEACDVIKPIVDAINYCHKMGIAHRDLKPENLLYTSPDPDATIKISDFGLAKVI-SDELM-TTACGTPS---YIAPEILEGKGYTFAVD
.    |.  . |. ..    | .. .| . ... ||||   | | |.   . ..||.|||||. | .|.   ... |..      ||| .  . .| . |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE---NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSD

YWSIGVILYVLLC-GFPP-FYEDTNEKLFAMI-KKGQ
 || || .. ..  |  | ... .|| ....| ..|.
VWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGY
Kinase 11728.AA TyrKc 82-336 23 1.3e-19 72.38 SMART 1-280 (280) Show / Hide 
Range on Protein: 82-336
Range on HMM: 1-280/280
Sequence Identity: 23% (70 aa)

FKFDKVLGEGSFAVVHKCIRKENNEEVAVKVIDKANLEHDDQLALETECEIMANI--DHPNIVKCT-CVYDEK------SKFYMVMELMTGGELFDRI-V
 ...|.|||| | .|.|.. |   ..||||.. .       . ..  | .|| ..  .|||||..  .. ...         ..|||.| .| | |..  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

EKEFYSEKEACDVIKPIVDAINYCHKMGIAHRDLKPENLLYTSPDPDATIKISDFGLAKVISDE--------LMTTAC--GTPS-----YIAPEILEGKG
 ..  . |. ..    | .  .| |.... ||||   | |....    |.|||||||.. | |.          ...   |. .       ||| .  . 
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YTFAVDYWSIGVILY-VLLCGFPPFYE-----DTNEKLFAMIKKGQFEFPSPQ-WDP-----ISNQAKDLIKNLLKVDPKQRYNAEQILNHA
.|.. | || || .. ..  | .| ..      .|. ... .|.|    . |    |      .    ...|   . ||..| . ..|    
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF