Gene 13265 (Tetrahymena)
13265
Sequence
Protein domains of 13265.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 13265.AA | CAMK1 | 77-339 | 45 | 7.2e-181 | 530.56 | In-house | 1-276 (276) | Show / Hide |
Range on Protein: 77-339 Range on HMM: 1-276/276 Sequence Identity: 45% (127 aa) YENIKILGKGTFAKVFLTKMVR---GGQEFAVKTFD-KRALLTSKNSEKTRTGLLNEIQILRKC---DHPNIIKLYEVYESDNYIYLVQNVLKGGELFDT ||..|..|.|.|..|.| .. . .|...|.| .| |... ..... | .. |.|||.|..|. |||||||.||.|||||..|||.. ..|||||| YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQ-K-QEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDR IIKNGNFSEKNAAKIIHQLLSALEYIHAKNIMHRDIKPENLILVDKSDDFQIK--LADFGLAAFTSDD--LLFKRCGTPGYVAPEILED---KKYDQKVD |...||..||.|..|..|.|||.||.|.|.|.|||.||||| ..||..|..|| .|||||. ....| |....||||||||||.||. | ||...| IVEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACD VFSSGVILYILLTGCSPFYGKS-YNEILSKNKNCQISYDFNELGVKVSQEATELLKKMLDVDPKTRITASQALNDRFF ..| |||.||||.|..|||... .||...|.|.|.. .. .. . ..||| ...|.||.|||| |.|..|.||.... MWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI |
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| Kinase | 13265.AA | Ciliate-E2a | 77-339 | 48 | 3e-148 | 439.47 | In-house | 1-275 (275) | Show / Hide |
Range on Protein: 77-339 Range on HMM: 1-275/275 Sequence Identity: 48% (134 aa) YENIKILGKGTFAKVFLTKMVRGGQEFAVKTFDKRALLTSKNSEKTRTGLLNEIQILRKCDHPNIIKLYEVYESDNYIYLVQNVLKGGELFDTIIKNGNF |. ||..|||.|..|.| . . |..||.| |.|.. . |..|. . |||.|.|. |||||||||||||..|..||| ..||||.| |.....| YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEY----FMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRF SEK--NAAKIIHQLLS-ALEYIHAKNIMHRDIKPENLILV--DKSDD--FQIKLADFGLAAFTSDDL---LFKRCGTPGYVAPEILEDKK------YDQK |. ....|. |||. .|.|.| .||||||.||||... .|... ..||..||||| | ..| .|..||||||||||.| | ||.| FEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTK VDVFSSGVILYILLTGCSPFYGKSYNEILSKNKNCQISYDFNELGVKVSQEATELLKKMLDVDPKTRITASQALNDRFF .|..| |||.||||.|..||.||.||||| .||.|.|... .| |.|.|. |.||||..||| |||| ||||. .| CDMWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF |
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| Kinase | 13265.AA | CAMK | 82-339 | 27 | 3.6e-119 | 385.83 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 82-339
Range on HMM: 1-425/425
Sequence Identity: 27% (116 aa)
ILGKGTFAKVFLTKMVRGG------------QEFAVKTFDKRALLTSKN---------------------SEKTRTGLLNEIQILRKC-------DHPNI
.||.|.|.||.| . . . |..|.| ||. | ..| ..|.| ...||.|..|. |||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
IKLYEVYES-------------------DNYIYLVQ---NVLKGGEL----FDTIIKNGN---------------FSEKNAAKIIHQLLSALEYIHAKNI
||||||||. |...|.| |||| || |...|. |.|. |.....|..||..|.| .||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI
MHRDIKPENLILVDKSDD--------------FQIKLADFGLAA-FTS------------------------DDLLFKRCGTPGYVA-PEILEDKK----
.|||.||||. |.|..|| ..||..|||.|. |.. .... .||||.|.| ||.|. |.
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM
----------YDQKVDVFSSGVILYILLTGCSPFYGK-------------SYNEILSKNKNCQISYDFNELGV-------------------KVSQEATE
|..|.|. | ||||||.|.|..||||. ...|.. | .... ... .. .||||.
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD
LLKKMLDVDPKTRITASQALNDRFF
|..||| |||. |.|..|.||. ..
LIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | 13265.AA | CDPK | 77-339 | 43 | 4.5e-111 | 341.87 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 77-339 Range on HMM: 1-271/271 Sequence Identity: 43% (122 aa) YENIKILGKGTFAKVFLTKMV-RGGQEF-AVKTFDKRALLTSKNSEK-TRTGLLNEIQILRKCDHPNIIKLYEVYESDNYIYLV--QNVLKGGELFDTII | |.||||.| |.. |. .|| |.|. |. . |..|. . ..||| ||.. |||||||.||.|. ....|.| ...|||||| || YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRV---KDKEQQQQ--FFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYII KNGNFSEKNAAKIIHQLLSALEYIHAKNIMHRDIKPENLILVDKSDD----FQIKLADFGLA-AFTSD-----DLLFKRCGTPGYVAPEILEDKKYDQKV .|.|.|| ||.|. |.|||. |.| .||.|||.||||. . |.|| ..||. |.|.. | .. . . .||||| |.|||.|. | |..|. EKGHFTEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKC DVFSSGVILYILLTGCSPFYGKSYNEILSKNKNCQISYDFNELGVKVSQEATELLKKMLDVDPKTRITASQALNDRFF |. | |||||||| | |||||. .||. | |... |.. | ..|.|| | .||| .||| |..|.|||.. | DIWSCGVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEW-DHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF |
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| Kinase | 13265.AA | S_TKc | 77-339 | 34 | 7.8e-99 | 335.57 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 77-339
Range on HMM: 1-231/231
Sequence Identity: 34% (95 aa)
YENIKILGKGTFAKVFLTKMVRGGQEFAVKTFDKRALLTSKNSEKTRTGLLNEIQILRKCDHPNIIKLYEVYESDNYIYLVQNVLKG--GELFDTIIKNG
|| ....|||.|.||.. . .. |...|.| . ...|||||.| .||||.|||.|... ...|.| . | |.||| | |.|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG
N------FSEKNAAKIIHQLLSALEYIHAKNIMHRDIKPENLILVDKSDDFQIKLADFGLAAFTSDDLLFKRCGTPGYVAPEILEDKKYDQ-KVDVFSSG
|.| |.....|...||||.| ..|.|||.||||. | . .||..|||||.. |||| |.|||.| .|. |.|. | |
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCG
VILYILLTGCSPFYGKSYNEILSKNKNCQISYDFNELGVKVSQEATELLKKMLDVDPKTRITASQALN-------DRFF
.|||..|.|. ||. ..... | . |.|| ....|.|..||. |.|| .||. . .|
CILYEMLCGYPPFP--QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
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| Kinase | 13265.AA | CAMKL | 77-339 | 35 | 2.8e-96 | 307.78 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 77-339
Range on HMM: 1-297/297
Sequence Identity: 35% (106 aa)
YENIKILGKGTFAKVFLTKM-VRGGQEFAVKTFDKRALLTSKNSEKTRTG--------LLNEIQILRKCD---HPNIIKLYEVYESDNY------IYLVQ
|. .| ||||.|.|| | . |.. |.| ||. . ...| | . ||||... . ||||||||||.| ... ||||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM
NVLKGGE--LFDTIIKNGN----FSEKNAAKIIHQLLSALEYIHAKNIMHRDIKPENLILVDKSDDFQIKLADFGLA-----A-FTSDDLLFKRCGTPGY
||| ||| |.|.|. ..|. | .. |..||..|.| ..| ||||||||. | .. . .||..|||.. |.....| .||.| |
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY
VAPEILED--KKYD-QKVDVFSSGVILYILLTGCSPFYGKSYN----EILSKNKNCQISYDFNE-LGVKVSQEATELLKKMLDVDPKTRITASQALNDRF
||||... |.|| .|||. | ||||| ...| || . .|| . . .. ... ... ..|| .. |..||| |.|. |.|. | .|...
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW
F
.
M
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| Kinase | 13265.AA | Pkinase | 77-339 | 31 | 2.1e-93 | 321.38 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 77-339 Range on HMM: 1-293/293 Sequence Identity: 31% (93 aa) YENIKILGKGTFAKVFLTKMVRGGQEFAVKTFDKRALLTSKNSEKTRTGLLNEIQILRKCDHPNIIKLYEVYESDNYIYLVQNVLKGG----ELFDTII- |. ....|.|.|..|.. . . |...|||...|| .|. ...|. .||||.....||||..||...|....||.|. . || .||| | YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL---SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST -KNGNF--SEKNAAKIIHQLLSALEYIHAKNIMHRDIKPENLILVDKSDDF--QIKLADFGLAA---FTSDDLLFKRCGTPGYVAPEILE-DKKYDQKVD ..|.| ||. . ... |.|..|||.|...|.|||.||||. .. . .. .|..|||||. .. . .||||.|.|||.. ...|..||| WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD VFSSGVILYILLTGCSPFYGK------SYNEILSKNKNCQISYDFN-----------------ELGVKVSQEATELLKKMLDVDPKTRITASQALNDRFF ..| |.|||..|.| ||.|. . .... ... .....|. .. ...|.|. ...|..|..||| |.|| |.|.. .| MWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | 13265.AA | Ciliate-E2 | 77-339 | 30 | 1.5e-92 | 313.75 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 77-339 Range on HMM: 1-365/365 Sequence Identity: 30% (116 aa) YENIKILGKGTFAKVFLTKMVRGGQEFA--VKTFDK--------------RALLTSKNSEKTRTGLLNEIQ--------------ILRKCDHPNIIKLYE |. ||..|.|.|..|.. | . ...|| ... .| |. . |.... . . | ||.. .||||||.|| YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE VYE--SDNYIYLVQNVLKGGELFDTIIKN-----------GNFSEKNAAKIIHQLLS---------------ALEYIHAKN-IMHRDIKPENLILVDKSD ... .||.|||| ..||.||| |..| ..|.|| ...|. |.|. ||||.| || |.||||||||... CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----- DFQIKLADFGLAAFTSDD---------------------------------LLFKRCGTPGYVAPEILEDKK---------YDQKVDVFSSGVILYILLT ||..||||. . .|| . . ||||||.|||||. || || |.|..| |||||..|. ---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF GCSPFYGKSYNEILSKNKNCQISYDFNE-------------LGVKVSQEATELLKK----MLDVDPKTRIT-ASQALNDRFF | || . ..|.|.|.....| |.|||. |.|| ||..||. ||| ..|.|| .| GKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | 13265.AA | CAMK-Unique | 77-339 | 28 | 3.2e-84 | 277.89 | In-house | 1-363 (363) | Show / Hide |
Range on Protein: 77-339
Range on HMM: 1-363/363
Sequence Identity: 28% (102 aa)
YENIKILGKGTFAKVFLTKMVRGGQEFAVKTFDK-----RALLT-------SKNSEKTRTG-LLNEIQILRKCDHPNIIKLYEV----YESDN-------
|....|.|.|.| .|. .. | ..|.| . | .... | .|| | | .|.||... |||||||||.. .. ..
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI
--------YIYLVQNVLKGGELFDTIIK--------------------NGNFSE--KNAAKIIHQLLSALEYIHAKNIMHRDIKPENLILVDKS--D---
|.|.|. . ||.||| |.| .| ||| .. |. .||||..| | ..| |||.|.|| |.| .| |
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLEN-IMVCYSFKDNNH
---------DFQIKLADFGLAAFTSDDLLF----KRCGTPGYVAP--------------EILEDKKYDQKV----DVFSSGVILYILLTGCSPFYGKSYN
. |||.||||.. . ..|||| |.|| |... .|||.. | | |||.|..|.||.||.. . .
HRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECED
--------EILSKNKNCQI-SYDFNELGVK--VSQEATELLKKMLDVDPKTRITASQALNDRFF
||... . ... ..| .. .||||. ..|. . |||. |..|...| ..
RDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
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| Kinase | 13265.AA | MARK | 77-339 | 36 | 4.8e-79 | 258.05 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 77-339 Range on HMM: 1-262/262 Sequence Identity: 36% (101 aa) YENIKILGKGTFAKVFLTKMVRGGQEFAVKTFDKRALLTSKNSE-KTRTGLLNEIQILRKCDHPNIIKLYEVYE--SDNY-IYLVQNVLKGGELFDTIIK |. .| .|.|..||| | .. |...|.|. .| | .. ... . ||.|..| ||||||||..| | . |||. ||||.| |.. YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEK-----FKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKA N--GNFSEKNAAKIIHQLLSALEYIHAKNIMHRDIKPENLILVDKSDDFQIKLADFGLAA-FTSDDLLFKRCGTPGYVAPEILEDKKYD-QKVDVFSSGV | .|. | .| .|..||..| | ||| |||||||| ||.|. .||..|||... .... .| |||| | ||||.. |.|| .|||. | || HPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPEN-ILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGV ILYILLTGCSPFYGKS--YNEILSKNKNCQISYDFNELGVKVSQEATELLKKMLDVDPKTRITASQALNDRFF .||....|. || |.. |.|. | ... .. .. || |. |....| |.|. |.|... ...... VLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH-----VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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| Kinase | 13265.AA | RSK | 80-339 | 32 | 2.6e-77 | 263.17 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 80-339
Range on HMM: 1-278/278
Sequence Identity: 32% (92 aa)
IKILGKGTFAKVFLTKMV---RGGQEFAVKTFDKRALLTS-KNSEKTRTGLLNEIQILRKCD-HPNIIKLYEVYESDNYIYLVQNVLKGGELFDTIIKNG
.| ||.| . |||| . . ||..|.| .|. . .. | . |.| |..|| | ||.|..|..... . ..||. ..|||||. . | .
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMT----ERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEK
N---FSEKNAAKIIHQLLSALEYIHAKNIMHRDIKPENLILVDKSDD-FQIKLADFGLAAF-TSD--DLLFKRCGTPGYVAPEILE---DKK-YDQKVDV
|||. |. .. .. .|.|..| . | |||.|||| .. |.| . ||| |||.. | .. . |.| |.|||.| .. .|. .|.
HFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDW
FSSGVILYILLTGCSPFYG---KSYNEILSKNKNCQISYDFN--ELGVKVSQEATELLKKMLDVDPKTRIT-----ASQALNDRFF
.| ||..| .||||.||.| .. .||. . .....| .. . ..|||| .|..||| .||. |.. |.. ... .|
WSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQ---YLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
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| Kinase | 13265.AA | Ciliate-E2-Unclassified | 77-339 | 24 | 3.4e-77 | 262.75 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 77-339
Range on HMM: 1-352/352
Sequence Identity: 24% (88 aa)
YENIKILGKGTFAKVFLTKMVRGGQEF-------AVKTFDKRALLTSKNSEKTRTGLLNEIQ-------------ILRKCDHPNIIKLYEVYESDNYIYL
|. ||..|.| |.||.. . . .. .. .... .... .. .|... ||. ..||.|.|.... .....||.
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI
VQNVLKGGELFDTIIKNGN-----------------FSEKNAA-----KIIHQLLSALEYIHAKN-IMHRDIKPENLILVDKSDDFQIKLADFGLAA---
| ..||.|.. | |... |.|..|. ... |.|..|||.| || | ||||||||... .. ..||..|||..
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ
--------------FTSDDLLFKRCGTPGYV----APEILEDKKYD----QKVDVFSSGVILYILLTGCSPFYGKSYNE---------------ILSKNK
....... .||||.| |||.|. ..|| |.|..| ||||| .|.| |||...... .| .|.
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI
NCQISYDFNELG----VKVSQEATELLK----KMLDVDPKTRITASQALNDRFF
. .. . ... ..|.|| .... |||...|. |||..|.|| .|
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
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| Kinase | 13265.AA | TyrKc | 77-338 | 24 | 8.3e-17 | 49.01 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 77-338 Range on HMM: 1-280/280 Sequence Identity: 24% (72 aa) YENIKILGKGTFAKVFLTKMVRGGQEFAVKTFDKRALLTSKNSEKTRTGLLNEIQILRKC--DHPNIIKLYEVYESD-------NYIYLVQNVLKGGELF . .|.|| | | .|.. .. .. |||. . | | ...|..|..| .||||..|| | .. ...| ..| | ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK DTIIKNGN-FSEKNAAKIIHQLLSALEYIHAKNIMHRDIKPENLILVDKSDDFQIKLADFGLAAFTSDD--------LLFKRC--GTPG-----YVAPEI | . |... .. | .. .| . ||.| ||. |||. | .||.. ..| .||||. . || |. |. . ||| DYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARN-CLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC LEDKKYDQKVDVFSSGVILYILLTGCSPFYG------KSYNEILSKNKNCQISYDFNE-----LGVKVSQEATELLKKMLDVDPKTRITASQALNDRF . ..|. | ||.| || .. ..| . . | .| |.. . |. . | ..| .. |. . ||. | | |. ..| INYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF-VCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF |
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| Kinase | 13265.AA | Pkinase_Tyr | 77-205 | 25 | 3e-11 | 38.71 | Pfam | 1-137 (270) | Show / Hide |
Range on Protein: 77-205 Range on HMM: 1-137/270 Sequence Identity: 25% (36 aa) YENIKILGKGTFAKVFLTKMV----RGGQEFAVKTFDKRALLTSKNSEKT--RTGLLNEIQILRKC-DHPNIIKLYEVYE-SDNY--IYLVQNVLKGGEL . .| ||.| | .|.. .. .... |||. | . ... | ...|..|... .||||..|| | . ||.| ..| | ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-----GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL FDTIIK----NGNFSEKNAAKIIHQLLSALEYIHAKNIMHRDI | | ..... | .. .| ...|| ..||. |||. LDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL |
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| Kinase | 13265.AA | Pkinase_Tyr | 211-291 | 31 | 0.014312 | 9.33 | Pfam | 142-227 (270) | Show / Hide |
Range on Protein: 211-291 Range on HMM: 142-227/270 Sequence Identity: 31% (28 aa) ILVDKSDDFQIKLADFGLAAFT-SDDLL-FKRCGTPG---YVAPEILEDKKYDQKVDVFSSGVILYILLTGC-SP-FYGKSYNEILSK .||.. ....| .||||| .|| || |.. ||| . ..|. | || | || .. ..| . .| ..| | .|.. . CLVTE--NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEY |
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