Gene 25722 (Tetrahymena)

25722

Species: Tetrahymena
Alias: 3823.m01092, 25722, PreTt25722, 187, TTHERM_00460710, 54.m00178
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CAMK
Family: CAMK-Tt

Sequence

Name Sequence Type Origin Length Description Download
25722.AA Protein None 730 None Fasta, JSON
25722.kin_dom Protein Kinase Domain None 255 None Fasta, JSON
25722.NA RNA None 2193 None Fasta, JSON

Protein domain

Protein domains of 25722.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 25722.AA CAMK-Tt 387-545 75 1.2e-129 437.04 In-house 236-396 (396) Show / Hide 
Range on Protein: 387-545
Range on HMM: 236-396/396
Sequence Identity: 75% (122 aa)

AISYMHSKYVCHRDLKPNNILCDETGDNVKITDFNVSKFCDSYKDYSNNNLPF-QGIKMWTYTGTIAFSAPEIFKENC-YDENIDIWSAGVILYTMLCGK
||.|||..||||||||||||||.|.|..|||||||||||||.||.|...||.. |.|||||||||.||||||||.|.| |||.||.||||.||||||||.
AIKYMHENYVCHRDLKPNNILCNEDGTCVKITDFNVSKFCDHYKNYKKDNLMNHQNIKMWTYTGTVAFSAPEIFNEDCCYDETIDMWSAGCILYTMLCGQ

EPFQAEFVKDLINKIIEGEYSFPSDPWDKISEEAKDLIKKCLTINPEDRIKPDMMLQHPWL
||||||.|.|||.||....|.|||..|..||||||||||||||||||.|||||.||||||.
EPFQAEYVHDLIKKICQADYNFPSHVWQHISEEAKDLIKKCLTINPEQRIKPDQMLQHPWI
Kinase 25722.AA CAMK 296-545 23 2e-99 321.07 In-house 1-425 (425) Show / Hide 
Range on Protein: 296-545
Range on HMM: 1-425/425
Sequence Identity: 23% (101 aa)

VLGEGCVGLVRKAIKITDQ------------SEYAVKIVRTR----------------------------DEETIMNIKNEFLHLRELQ-------HKNI
.||.|  | |...| . ..             ..|.||. ..                            ....  |...|   .. ||       |.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKVYEIYIDK----------TKGK--------IYTIM---ELIKGREM----FEVINQLGS---------------Y-------------SAISYMHSKY
.| ||.| |.          |  |        .| .|   |.. | |.    |. | . |.               .             ||. |.||. 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VCHRDLKPNNILCDETGD----------------NVKITDFNVSKFCDSYKDYSNNNLPF------------QGIKMWTYTGTIAFSA-PEIFK------
..|||||| |||.|. .|                |.||.||  ....|. ... ... .             .| ||.|. || .. | ||...      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------ENCYDENIDIWSAGVILYTMLCGKEPFQAEFVKDLIN-------------KIIEGEYSFPSDP------------WDKISEE--------AK
        .  |.. .|.||.|||||.||||. ||...  .. ..             ||..|.|.||...            ||.||.|        .|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLIKKCLTINPEDRIKPDMMLQHPWL
|||.|.|. .||.|.. .  |.|||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
S_TKc 25722.AA S_TKc 291-545 30 2.4e-77 264.17 SMART 1-231 (231) Show / Hide 
Range on Protein: 291-545
Range on HMM: 1-231/231
Sequence Identity: 30% (85 aa)

YELQDVLGEGCVGLVRKAIKITDQSEYAVKIVRTRDEETIMNIKNEFLHLRELQHKNIVKVYEIYIDKTKGKIYTIMELIKG--REMFEVINQLGSY---
||. ...|.|  | |.|.... .. ..|.||..        .|..|   |.. .|.|||| |... |   ...| .||.. |   ..|..| . |.    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

---------------SAISYMHSKYVCHRDLKPNNILCDETGDNVKITDFNVSKFCDSYKDYSNNNLPFQGIKMWTYTGTIAFSAPEIFKENCYDE-NID
               .|. |.||. ..|||||| |||.||   ..||.|| ....                    |. ||  . |||..    |.   .|
FPFPEHARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------------------TTFCGTPWYMAPEVL---GYGKCKCD

IWSAGVILYTMLCGKEPFQAEFVKDLINKIIEGEYSFPSDPWDKISEEAKDLIKKCLTINPEDRIKPDMMLQ-------HPWL
.|| |.||| ||||. ||.   .. ...||               |.||||.|.|||. .||.|.     ||       |||.
WWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 25722.AA Ciliate-E2 291-545 25 1.1e-74 254.38 In-house 1-365 (365) Show / Hide 
Range on Protein: 291-545
Range on HMM: 1-365/365
Sequence Identity: 25% (95 aa)

YELQDVLGEGCVGLVRKAIKITDQ-----------------------SEYAVKIVRTRDEETIMNIKNEF--LH-----------LRELQHKNIVKVYEI
|... ..|.|. | |.|. .. .|                       ..||.||.. .. | |.......  ..           |..|.|.||.| || 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YIDKTKGKIYTIMELIKGREMFE-------------------VINQLGSY-----S---------------AISYMHSKY-VCHRDLKPNNILCDETGDN
...|.. .|| .||...| ..|.                   .... . .     .               |. |.|||  ..|||.||.|||       
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

VKITDFNVSKFCD-SYKDYS----NNNLPFQG----------------IKMWTYTGTIAFSAPEIFK---------ENCYDENIDIWSAGVILYTMLCGK
.||.||  ||..| ......    .....| .                   .|. ||  . ||||..         .. ||. .||||.||||| ||.||
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

EPFQAEFVKDLINKIIEGEYSFPSD--------------PWDKISEEAKDLIKK----CLTINPEDRIK-PDMMLQHPWL
 ||        ...|......||.                |.|.|.|.||||||    .|  .|| ||  ..  |.|||.
PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 25722.AA Pkinase 291-545 29 3.3e-71 247.68 Pfam 1-293 (293) Show / Hide 
Range on Protein: 291-545
Range on HMM: 1-293/293
Sequence Identity: 29% (92 aa)

YELQDVLGEGCVGLVRKAIKITDQSEYAVKIVRTRDEETIMNIKN----EFLHLRELQHKNIVKVYEIYIDKTKGKIYTIMELIKGR----EMFEVIN--
|..  ..|.|  | |.|.... .. ..||||.. |.|.  ... .    |   ...|.|.|||. |... |  |..|| .||.  |     . |..|   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTW

QLGSY---------------SAISYMHSKYVCHRDLKPNNILCDETGDN---VKITDFNVSKFCDSYKDYSNNNLPFQGIKMWTYTGTIAFSAPEIFK-E
. |..               ... |.||. ..|||||| |||.|..|..   |||.|| ..|. |         .  ..  |.|..||. . |||. .  
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---------Y-NNS--MTTFCGTPWYMAPEVIRGG

NCYDENIDIWSAGVILYTMLCGKEPFQAE------FVKDLINKIIEGEYSFPSDPWDKIS-----------------EEAKDLIKKCLTINPEDRIKPDM
. |.  .|.||.|.||| ||||. ||. .        . .|..| .....|... |. ||                 ||.||.||.||. .|..|. .. 
QYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQ

MLQHPWL
 |||||.
ILQHPWF
Kinase 25722.AA CDPK 291-545 36 1.9e-68 209.11 In-house 1-271 (271) Show / Hide 
Range on Protein: 291-545
Range on HMM: 1-271/271
Sequence Identity: 36% (104 aa)

YELQDVLGEGCVGLVRKAIKI-TDQSEY-AVKIV---RTRDEETIMNIKNEFLHLRELQHKNIVKVYEIYIDKTKGKIYTIME--LIKGREMFEVINQLG
| . .|||.|  | |||...   .. |  |.||.   | .|.| . . .||.  |..| | ||.|.|| | |.    .| .||  . .| | |..| . |
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEK--NYYIVMETEYCTGGELFDYIIEKG

SY-------------SAISYMHSKYVCHRDLKPNNIL--CDETGD----NVKITDFNVSKFCDS-YKDYSNNNLPFQGIKMWTYTGTIAFSAPEIFKENC
..             ||..|.||. ..|||||| |||   .....    |.|. |.  || .|.  |         .. || .  ||.   |||. . . 
HFTEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKI--------EDKKMSQRCGTPYYIAPEVLQKK-

YDENIDIWSAGVILYTMLCGKEPFQAEFVKDLINKIIEGEYSFPSDPWDKISEEAKDLIKKCLTINPEDRIKPDMMLQHPWL
|.|  ||||.|||||..|||  || ..  .. ..|. .|.|||  . ||.||.||||||.|.|. .|..|.. .. ||||| 
YNEKCDIWSCGVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase 25722.AA Ciliate-E2a 291-545 29 2.3e-68 200.33 In-house 1-275 (275) Show / Hide 
Range on Protein: 291-545
Range on HMM: 1-275/275
Sequence Identity: 29% (84 aa)

YELQDVLGEGCVGLVRKAIKITDQSEYAVKIVRTRDEETI---MNIKNEFLHLRELQHKNIVKVYEIYIDKTKGKIYTIMELIKGREMF-----------
|......|.|. | |..| .. .  ..|.|..  .....     ...||   .|.| |.|| | ||.|.|..   .| .||...|.|..           
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDEN--NYYLVMEYCEGGELYDKIKQCKRFFE

---EVINQLGSYS--AISYMHSKYVCHRDLKPNNILCD---ETG---DNVKITDFNVSKFCDSYKDYSNNNLPFQGIK--MWTYTGTIAFSAPEIFKENC
   |.  ..      ...|||.. . |||||| ||| .    ..    ..|| ||  ..|.|..            .|  | .  ||  . |||...   
EIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKD------------EKKYMFQKCGTPGYVAPEVLNNKE

------YDENIDIWSAGVILYTMLCGKEPFQAEFVKDLINKIIEGEYSFPSDP-WDKISEEAKDLIKKCLTINPEDRIKPDMMLQHPWL
      ||.  |.||.|||.|..|||| ||... ... . .. . ...| .   | |.| |.|||.|| |  .|. ||..   |.||| 
VLKHKQYDTKCDMWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 25722.AA Ciliate-E2-Unclassified 291-545 24 1.7e-67 230.56 In-house 1-352 (352) Show / Hide 
Range on Protein: 291-545
Range on HMM: 1-352/352
Sequence Identity: 24% (87 aa)

YELQDVLGEGCVGLVRKAIKITDQSEY------------AVKIVRTRDEETIMNIKNEFLHL--------RELQ-----HKNIVKVYEIYIDKTKGKIYT
|... ..|.|. | |.|.... .. .|            ..|.... | | ....| .. .         ...|     |.....|...|....| .|| 
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

IMELIKGREMFEVINQLGS-----------------------------------YSAISYMHSKY-VCHRDLKPNNILCDETGD--NVKITDFNVSK---
.||...| .... |.. ..                                    ....|.|.|  ..|||.||.||| |. |   ..||.||  ||   
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

FCDSYKDYSN--NNLPFQGIKMWTYTGTIAFS----APEIFKENCYD----ENIDIWSAGVILYTMLCGKEPFQAEFVKD----------------LINK
 .. .. ...  .   ..  .||| .||. .     |||..... ||    . .|||| ||||| || |. ||...  ..                |...
QNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQN

IIEGEYSFPSDPW----DKISEEAKDLIK----KCLTINPEDRIKPDMMLQHPWL
|......||. ||    ...|.||||.|.    |.|  ||. || ..  |.|||.
IKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 25722.AA CAMK1 387-545 39 8.1e-65 187.33 In-house 120-276 (276) Show / Hide 
Range on Protein: 387-545
Range on HMM: 120-276/276
Sequence Identity: 39% (67 aa)

AISYMHSKYVCHRDLKPNNILCDETGDN--VK--ITDFNVSKFCDSYKDYSNNNLPFQGIKMWTYTGTIAFSAPEIFKE---NCYDENIDIWSAGVILYT
|. ||||| ..|||||| |.|.    ..  .|  | ||  ||..|.  .           .| |  ||. . |||...      ||  .|.||.|||.|.
AVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDEN-----------LMKTACGTPGYVAPEVLECKKDKPYDKACDMWSIGVITYI

MLCGKEPFQAEF-VKDLINKIIEGEYSFPSDPWDKISEE-AKDLIKKCLTINPEDRIKPDMMLQHPWL
.||| .||..|   . |  ||...|| |||. ||.||.. |||.||. |. .|. |.  .  |.|||.
LLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase 25722.AA CAMK-Unique 291-545 22 5.5e-62 203.33 In-house 1-363 (363) Show / Hide 
Range on Protein: 291-545
Range on HMM: 1-363/363
Sequence Identity: 22% (84 aa)

YELQDVLGEGCVGLVRKAIKITDQSEYAVKIVRT-RDEETIMNI-------------------KNEFLHLRELQHKNIVKVYEI----YIDKTK------
|..  ..|.|  |.|.... ..   ..|.|.|.  .... .. .                   |.|   .. . | ||.|.|..    . |...      
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

-------GKIYTIMELIKGREMFEVINQ--------------------LGSYSA---------------ISYMHSKYVCHRDLKPNNILCDETGD-----
        ..|..||.. |...|..|..                     |..|.               ..||||. . |||||. ||.  . ..     
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

----------NVKITDFNVSKFCDSYKDYSNNNLP-FQGIKMWTYTGTIAFSAP--------------EIFKENCYDENI----DIWSAGVILYTMLCGK
          ..|..||  .      ..|..|  .      | |. ||. . ||              |. .. |||.      |||| |||.|.||||.
RDFPYDWSNWHIKLCDFGLC------CHYNHNKMCHM----MQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGC

EPFQAEFVK--------DLINKIIEGEY-SFPSDPWDK---ISEEAKDLIKKCLTINPEDRIKPDMMLQHPWL
 || .|. .         .. .|  |.| .|... |.    ||.||||..|.|.|. |  |..    |.|.|.
PPFDCECEDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 25722.AA CAMK-Tt 291-386 46 1.7e-61 210.61 In-house 1-135 (396) Show / Hide 
Range on Protein: 291-386
Range on HMM: 1-135/396
Sequence Identity: 46% (63 aa)

YELQDVLGEGCVGLVRKAIKITDQSEYAVKIVRTRDEETIM---------------------------------------NIKNEFLHLRELQHKNIVKV
||.|..|||||||||.|...|.|....|.|.|||||||.||                                       ....||...|||.|.|||||
YEEQEILGEGCVGLVKKVKRISDGQVFACKMVRTRDEEEIMNHQSYNSEISSGQHKCQSTGELFEITKFTYFKSISQSKMQVIREFKNIRELNHPNIVKV

YEIYIDKTKGKIYTIMELIKGREMFEVINQLGSYS
||.|||.|||.||||||||...||||||..||.||
YELYIDETKGRIYTIMELIEAKEMFEVIHKLGHYS
Kinase 25722.AA RSK 293-545 28 4.5e-59 202.56 In-house 1-278 (278) Show / Hide 
Range on Protein: 293-545
Range on HMM: 1-278/278
Sequence Identity: 28% (83 aa)

LQDV--LGEGCVGLVRKAIKITDQSEYAVKIVRTRDEET----IMNIKNEFLHLRELQ-HKNIVKVYEIYIDKTKGKIYTIMELIKGREMFEVINQLGS-
|..   .| | | |.|| .    . .||.|... .   .    .   . |   | . | |..||. .. .  .|.||.| |||...| |.|. . . .. 
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAF--QTEGKLYLIMEYCRGGELFTHLQKEKHF

---------------YSAISYMHSKYVCHRDLKPNNILCDE-TGD--NVKITDFNVSKFCDSYKDYSNNNLPFQGIKMWTYTGTIAFSAPEIFK---ENC
                .|....|.. . |||||| ||| |. . .   .|.|||  .|             . .. .. |. .||.. |||. |    ..
GCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQF----------RCDHNQWTMTFCYTIEYMAPEMLKRANQQG

-YDENIDIWSAGVILYTMLCGKEPFQA---EFVKDLINKIIEGEYSFPSDPWDKISEEAKDLIKKCLTINPEDRIK-----PDMMLQHPWL
 .|.. |.|| ||..|.|| |. |||.   .  |.....| .|..|.... |...|.||||||.|.|. .|..|..      .  .||||.
GHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 25722.AA CAMKL 449-545 38 2.4e-33 103.64 In-house 195-297 (297) Show / Hide 
Range on Protein: 449-545
Range on HMM: 195-297/297
Sequence Identity: 38% (42 aa)

GTIAFSAPEIFKE--NCYD-ENIDIWSAGVILYTMLCGKEPFQAE--------FVKDLINKIIEGEYSFPSDPWDKISEEAKDLIKKCLTINPEDRIKPD
|. .. |||||.     ||   .||||.|||||.|.||. || ..         .  | .||..| | .|  .| ..| ...|||.| |. |||.|.. .
GSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPP--IWYHVS-DCRDLIRKMLQVNPEKRPTIH

MMLQHPWL
  ..|||.
QIMNHPWM
Kinase 25722.AA CAMKL 291-420 30 4.9e-33 102.66 In-house 1-173 (297) Show / Hide 
Range on Protein: 291-420
Range on HMM: 1-173/297
Sequence Identity: 30% (53 aa)

YELQDVLGEGCVGLVRKAIK-ITDQSEYAVKIVR----TRDEETIMN-----------IKNEFLHLRELQ---HKNIVKVYEIYIDKTK----GKIYTIM
|.. ..||.|  | |. |.  .| . ..|.||.     . |. . .|           |. |   .. |.   |.||.| ||.. ....    .||| .|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELIKGRE--MFEVINQLGS-----------------YSAISYMHSKYVCHRDLKPNNILCDETGD-NVKITDF
|.. | |  .|. | . |                   ||..|.||. ..|||.|| ||| || |. |.||.||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDF
Kinase 25722.AA CAMK1 291-386 25 9e-15 39.31 In-house 1-106 (276) Show / Hide 
Range on Protein: 291-386
Range on HMM: 1-106/276
Sequence Identity: 25% (27 aa)

YELQDVLGEGCVGLVRKAIKIT---DQSEYAVKIVR-TR--DEETI---MNIKNEFLHLR---ELQHKNIVKVYEIYIDKTKGKIYTIMELIKGREMFEV
||.....|.|  . |......    .. .||.|.    .  ....    ....||   ..   ...| ||.| ||.|   .. ..| .|||..| | |. 
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWY--ESDNHFYLVMELVTGGELFDR

INQLGSYS
| . |.|.
IVEKGNYT
Kinase 25722.AA TyrKc 291-538 20 1.9e-12 -21.34 SMART 1-280 (280) Show / Hide 
Range on Protein: 291-538
Range on HMM: 1-280/280
Sequence Identity: 20% (61 aa)

YELQDVLGEGCVGLVRKAIKITDQSEYAVKIVRTRDEETIMNIKNEFLHLREL--QHKNIVKVYEIYIDKTK-----GKIYTIMELIKGREMFEVINQLG
 .| ..||||. | |.|.. .    . ||| ..      .. . .|   ...|  .|.|||. | . ...       . .. .||. ..    . .   .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

SY--------------SAISYMHSKYVCHRDLKPNNILCDETGDNVKITDFNVSKFCDSY-------KDYS-----NNN--LPFQGIKMWTYTGTIAFSA
                .  .| ||| . ||||   |.| .| .  |||.||  |.. ...       . |.     . .  ||            |   |
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLP------------IRWMA

PEIFKENCYDENIDIWSAGVILYTML-CGKEPFQA-----EFVKDLINKIIEGEYSFPSDP-----WDKISEEAKDLIKKCLTINPEDR-----IKPDM
|| ...... .  |.|| || .. ..  |..|           ...|... .|..  . .          ..|  ...|.|   .||||     |. ..
PECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF