Gene 23028 (Tetrahymena)

23028

Species: Tetrahymena
Alias: 23028, TTHERM_00105280, 7.m00477, PreTt23028, 35
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CK1
Family: CK1
Subfamily: CK1-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
23028.AA Protein None 542 None Fasta, JSON
23028.kin_dom Protein Kinase Domain None 245 None Fasta, JSON
23028.NA RNA None 1629 None Fasta, JSON

Protein domain

Protein domains of 23028.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 23028.AA CK1-Unclassified 14-266 62 1.6e-205 612.52 In-house 1-244 (244) Show / Hide 
Range on Protein: 14-266
Range on HMM: 1-244/244
Sequence Identity: 62% (162 aa)

YKIVKKLGSGAFGEIFLAINRQNGEEYAVKVEEANSRHPQIMFEAKLYNYLNNGSSSESGLNNSISGTSSYSSSDKGIPRVYFCGQD--QGYNIMVMDLL
|....|.|.|.||||...|| |..||.|.|.|..||.|||...|||...||.||... ...            . ||||..| |||.  ..|||||||||
YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSKHPQLCYEAKIMQYLQNGHNC-DNF------------I-KGIPKMYWCGQEEQGDYNIMVMDLL

GESLEDLFVKVGRKFSLKTVLMLVDQMIQRIEFMHSRNFLHRDIKPDNFLMG-GPKRSNKCYLIDLGLAKRYI--DKFGKHIPYRENKNLTGTARYASIN
|.||||||.. .||||||||||..||||||||..|..||.||||||||||||   |.....|.||.||.||||  || ||||||||||||||||||||||
GPSLEDLFNMCNRKFSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASIN

THVGIEQGRRDDLESLGYVIMYFLRGILPWQNLKAEGKKDKYERIMEKKMQTPVEVLC
.| ||||.|||||||||||..|||.| |||||.||. ||.|||.|||.||.|||| ||
AHLGIEQSRRDDLESLGYVLIYFLKGSLPWQNIKANNKKEKYEKIMEMKMSTPVEQLC
Kinase 23028.AA CK1 14-292 62 6.1e-197 660.55 In-house 1-271 (271) Show / Hide 
Range on Protein: 14-292
Range on HMM: 1-271/271
Sequence Identity: 62% (178 aa)

YKIVKKLGSGAFGEIFLAINRQNGEE--YAVKVEEANSRHPQIMFEAKLYNYLNNGSSSESGLNNSISGTSSYSSSDKGIPRVYFCGQD--QGYNIMVMD
|....|.|.|.||.|.|.|| .||||  .|.|.|...|.|||...|||.|..|... .. ..             ...|||..| |||.  . |||||||
YRVGRKIGQGSFGDIYLGINMTNGEENHVAIKLEKNKSKHPQLHYEAKIYKILQGH-NC-DN-------------QCHGIPHMYWCGQEEQGDYNIMVMD

LLGESLEDLFVKVGRKFSLKTVLMLVDQMIQRIEFMHSRNFLHRDIKPDNFLMGG-PKRSNKCYLIDLGLAKRYID-KFGKHIPYRENKNLTGTARYASI
|||.|||||| . .||||||||||..||||||||..|..||.||||||||||||   |.....|.|| ||||||.| | ..|||||||||||||||||||
LLGPSLEDLFNFCNRKFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASI

NTHVGIEQGRRDDLESLGYVIMYFLRGILPWQNLKAEGKKDKYERIMEKKMQTPVEVLCKG-FPTEFATYLQYCKNLRFEDKPDYS
||| ||||.||||.||||||.|||||| ||||.|||. ||.|||.||||||.||||.|||| || |||.||.||..|.||.|||| 
NTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKANTKKQKYEKIMEKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM
Kinase 23028.AA CK1-D 14-294 59 5.1e-145 488.06 In-house 1-261 (261) Show / Hide 
Range on Protein: 14-294
Range on HMM: 1-261/261
Sequence Identity: 59% (169 aa)

YKIVKKLGSGAFGEIFLAINRQNGEEYAVKVEEANSRHPQIMFEAKLYNYLNNGSSSESGLNNSISGTSSYSSSDKGIPRVYFCGQDQGYNIMVMDLLGE
|.| .|.|||.||.|..  | |..|| |.|.| . ..|||. .|.|.| ... |                      |||.. .|||.  ||.||||||| 
YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTKHPQLHIESKFYKMMQGGI---------------------GIPEIRWCGQEGDYNVMVMDLLGP

SLEDLFVKVGRKFSLKTVLMLVDQMIQRIEFMHSRNFLHRDIKPDNFLMGGPKRSNKCYLIDLGLAKRYIDKF-GKHIPYRENKNLTGTARYASINTHVG
||||||   .||||||||||| ||||.|||..|.|||.||||||||||||  || |  |.|| |||||| |    .|||||||||||||||||||||| |
SLEDLFNYCHRKFSLKTVLMLADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQG

IEQGRRDDLESLGYVIMYFLRGILPWQNLKAEGKKDKYERIMEKKMQTPVEVLCKGFPTEFATYLQYCKNLRFEDKPDYSHC
||| |||||||||||.||| || |||| |||  |..|||||.||||.|....||||.| ||..|. ||.||.|.|||||.. 
IEQSRRDDLESLGYVLMYFNRGSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL
Kinase 23028.AA CK1-A 14-294 58 4.8e-140 471.54 In-house 1-261 (261) Show / Hide 
Range on Protein: 14-294
Range on HMM: 1-261/261
Sequence Identity: 58% (164 aa)

YKIVKKLGSGAFGEIFLAINRQNGEEYAVKVEEANSRHPQIMFEAKLYNYLNNGSSSESGLNNSISGTSSYSSSDKGIPRVYFCGQDQGYNIMVMDLLGE
|..|.|.|||.||.|.|.|| .|||| |.|.|... ||||...|||.|. |. .                      |||.. . |... ||.||||||| 
YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARHPQLIYEAKVYRILQGCV---------------------GIPHMRWYGCEKDYNVMVMDLLGP

SLEDLFVKVGRKFSLKTVLMLVDQMIQRIEFMHSRNFLHRDIKPDNFLMGGPKRSNKCYLIDLGLAKRYIDKFGK-HIPYRENKNLTGTARYASINTHVG
||||||    |.|..||||||.|||| |||..| .||.||||||||||||  .  || .||| ||||.| |.  . |||||| ||||||||||||| |.|
SLEDLFNFCKRRFTMKTVLMLADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLG

IEQGRRDDLESLGYVIMYFLRGILPWQNLKAEGKKDKYERIMEKKMQTPVEVLCKGFPTEFATYLQYCKNLRFEDKPDYSHC
||| ||||.||.|||.||| || |||| .||  || |||.| |||| ||.|.||||||.||. |..||.|||||..||| . 
IEQSRRDDMESMGYVMMYFNRGKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL
Kinase 23028.AA CK1 14-294 37 1.7e-132 446.46 In-house 1-339 (339) Show / Hide 
Range on Protein: 14-294
Range on HMM: 1-339/339
Sequence Identity: 37% (131 aa)

YKIVKKLGSGAFG-EIFLA-----INRQNG-----EEYAVKVEEANSR--HPQIMFEAKLYNYLNNG----SSSESGLNNSISGTSSYSSS---DKGIPR
.|.|||.|.|.|| .|...     .. .|.     ||||.||| ..|.  ||| | |...|..|..|    . | ..       .. ....    ...|.
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKA-S-IL-------KHKHFCKKHCGCPHPC

VYFCGQDQG--YNIMVMDLLGESLEDLFV---KVGRKFSLKTVLMLVDQMIQRIEFMHSRNFLHRDIKPDNFLMGG-------------PKRSNKCYLID
.| ... ..  ||.|||.|||..||||.      .||||.||.||. .||....|.||...|.|||||||||.||               ..... |.||
MYWYHGEEDDYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMID

LGLAK-RYIDK------------FGKHIPYRE---NKNLTG-TARYASINTHVGIEQGRRDDLESLGYVIMYFLRGI--LPWQNLKAEGK-------KDK
 |.|. .|.||             ..|.|.||   .|...| ||||.|||.| |.||||||||.|..|.....|.|   |||||.|.| |       | |
FGMARRKYRDKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMK

YERIMEKKMQTPVEVLCKG-----FPTEFATYLQYCKNLRFEDKPDYSHC
|| |.||||.||.. ||..     .| || ....|...|...|.|||   
YEFIDEKKMSTPFF-LCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase 23028.AA CK1-G 14-294 49 5.2e-128 431.56 In-house 1-266 (266) Show / Hide 
Range on Protein: 14-294
Range on HMM: 1-266/266
Sequence Identity: 49% (142 aa)

YKIVKKLGSGAFGEIFLAINRQNGEEYAVKVEEANSRHPQIMFEAKLYNYLNNGSSSESGLNNSISGTSSYSSSDKGIPRVYFCGQDQGYNIMVMDLLGE
|.. || | | |||.|.  |  |.|  |.| |   || ||   | . |  ||  .                     |||.||. ||   |||||||||| 
YRVGKKIGCGNFGELFEGKNMYNNEHVAIKFEPMKSRAPQLHDEYRFYKILNGCP--------------------EGIPQVYYFGQCGKYNIMVMDLLGP

SLEDLFVKVGRKFSLKTVLMLVDQMIQRIEFMHSRNFLHRDIKPDNFLMG--GPKRSNKCYLIDLGLAKRYID-KFGKHIPYRENKNLTGTARYASINTH
||||||   .||||.|||.|.  |||.|.| .||.. . ||.|||||| |  . |. .. ..|| |.|| ||| . ..|||||| | ||||||| |||||
SLEDLFDWCDRKFSVKTVCMVAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYIDPETKQHIPYREHKSLTGTARYMSINTH

VGIEQGRRDDLESLGYVIMYFLRGILPWQNLKAEGKKDKYERIMEKKMQTPVEVLCKG--FPTEFATYLQYCKNLRFEDKPDYSHC
 | || ||||.|.|| . |||||| |||| |||.  | .|..| ..| .|..|.||..  || .|||||.|  .| |...||| . 
LGREQSRRDDMEALGHMFMYFLRGSLPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL
Kinase 23028.AA TTBK 93-294 44 5.1e-51 175.8 In-house 60-257 (257) Show / Hide 
Range on Protein: 93-294
Range on HMM: 60-257/257
Sequence Identity: 44% (91 aa)

RVYFCGQDQGYNIMVMDLLGESLEDLFVKVGR-KFSLKTVLMLVDQMIQRIEFMHSRNFLHRDIKPDNFLMG-GPKRSNKCYLIDLGLAKRYIDKFGKHI
| . || .  .| |||.|.|..| ||  |  | .||| | | |  |..| ||  ||  |||||||| || ||  |.. .|||..| ||| .|.   |   
RFIGCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFSLSTTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYTNACGEVR

PYRENKNLTGTARYASINTHVGIEQGRRDDLESLGYVIMYFLRGILPWQNLKAEGKKDKYERIMEKKMQTPVEVLCKGFPTEFATYLQYCKNLRFEDKPD
| ||     ||.|||||| |   | ||.||| || |.   |. | |||  .     ||| . . | | .    .| |  | || ....  | | .||.||
PPREVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVQGQLPWRKI-----KDK-DQVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPD

YSHC
|   
YQLI
Kinase 23028.AA TTBKL 91-298 31 8e-45 149.29 In-house 62-288 (288) Show / Hide 
Range on Protein: 91-298
Range on HMM: 62-288/288
Sequence Identity: 31% (74 aa)

IPRVYFCGQDQGYNIMVMDLLGESLEDLFVKVGRK--FSLKTVLMLVDQMIQRIEFMHSRNFLHRDIKPDNFLMGGPKR----SNKCYLIDLGLAKRYID
.|.....|. ..|| ||| |.|..| ||  .  .|  ||  |.. .  | .  .  ||.  |.|||.|| |. .|  ..    .   |||| |.|..|..
FPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFSDGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAW

KFG-----------KHIPYRE---NKNLTGTARYASINTHVGIEQGRRDDLESLGYVIMYFLRGILPWQNLKAEGKKDKYERIMEKKMQTPVEVLCKG--
| |           .. . |.      . || ||.|.| | . |||| ||| |. |.|.... | |||.|.. .      ..|...|...  |.|.|.  
KDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNMHDRKEQGRHDDLWSWMYMIIELHCG-LPWTNMEDK------MEIEHMKKNMKDEDLFKDMP

----FPTEFATYLQYCKNLRFEDKPDYSHCRQLF
    .| ||.   .. ..||. | |||.  ...|
RDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF
Kinase 23028.AA Worm6 102-294 30 8.8e-45 155.1 In-house 76-279 (279) Show / Hide 
Range on Protein: 102-294
Range on HMM: 76-279/279
Sequence Identity: 30% (62 aa)

GYNIMVMDLLGESLEDLFVKV-GRKFSLKTVLMLVDQMIQRIEFMHSRNFLHRDIKPDNFLMGGP-----KRSNKCYLIDLGLAK--RYIDKFGKHIPYR
|.| .|| |.|..|.||     .||||. | | .  |....|| .|.  |.|||.|| ||  | .     . . . |..| |...  .|..| .. .. |
GFNYIVMTLVGKNLWDLRKNRPDRKFSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPR

-ENKNLTGTARYASINTHVGIEQGRRDDLESLGYVIMYFLRGILPWQNLKAEGKKD-KYERIMEKKMQTPVEVLCKGFPT-EFATYLQYCKNLRFEDKPD
 ..    || |||... | |.||.|.||.||  |..  ...| |||...|..  ..  ..... ..  .  . . ...|. ||   ..|  .....|.||
WTACGFRGTVRYAPLACHKGQEQCRKDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPD

YSHC
| ..
YKFI
Kinase 23028.AA Pkinase 14-257 20 4.6e-32 114.46 Pfam 1-234 (293) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-234/293
Sequence Identity: 20% (54 aa)

YKIVKKLGSGAFGEIFLAINRQNGEEYAVKVEEANSRHP--QIMF----EAKLYNYLNNGSSSESGLNNSISGTSSYSSSDKGIPRVYFCGQDQGYNIMV
|.|..|.|||.||. ...... .|...|||. .  ....  ..      |... . ||                     ..  .   ...    ..  ||
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN---------------------HPNIVRLYDWFED-KDHIYMV

MDLLGESLE--DLF----VKVGRKF--SLKTVLMLVDQMIQRIEFMHSRNFLHRDIKPDNFLMGGPKRSNKC---YLIDLGLAKRYIDKFGKHIPYRENK
|....  |.  |||    .. ...|  | ... . . |... .|..||....|||.||.|.|.   .. . .    ..| |||| .      . ... ..
MEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID--NNGHIDACVKICDFGLAKQFD-----Y-NNS-MT

NLTGTARYASINTHV-GIEQGRRDDLESLGYVIMYFLRGILPWQNL----KAEGKKDKYERIMEKK
 ..|| .|..   .  | . |.. |  |.| .. ..| | .|...     .   .. ...|||...
TFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPP
Kinase 23028.AA VRK 106-242 40 4.5e-25 77.61 In-house 106-244 (284) Show / Hide 
Range on Protein: 106-242
Range on HMM: 106-244/284
Sequence Identity: 40% (56 aa)

MVMDLLGESLEDLFV-KVGRKFSLKTVLMLVDQMIQRIEFMHSRNFLHRDIKPDNFLMGGPKRSNKCYLIDLGLAKRYIDKFGKHIPYRENKNLT--GTA
|||. .|..|. .     | .|| |||| |  .|.   |..|. .  | |||  | | |  |  .. ||.| ||| || .  ||| .| |..     || 
MVMPRFGRDLQKIYEDQNGHRFSMKTVLQLACRMLDVLEYLHENEYVHGDIKAANILLGFEKNPDQVYLVDYGLAYRYCPN-GKHRQYKEDPRRCHNGTC

RYASINTHVGIEQGRRDDLESLGYVIMYFLRGILPWQNLK
 . |.  | |    || |||.|||  |. | | ||| ...
EFTSMDAHKGCAPSRRSDLEILGYCMMMWLYGYLPWMDCL
Kinase 23028.AA S_TKc 14-316 16 6e-16 57.0 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-316
Range on HMM: 1-231/231
Sequence Identity: 16% (52 aa)

YKIVKKLGSGAFGEIFLAINRQNGEEYAVKVEEANSRHPQIMFEAKLYNYLNNGSSSESGLNNSISGTSSYSSSDKGIPRVYFCGQDQGYNIMVMDLLGE
|.|..|.|.||||. ......  |...|.|.                     .   .|  .  .           . | . | . || ..  |||.... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------------EHIRREIQILKK---------HHPNIVKLYDVFQD-DHLYMVMEYCDG

---SLEDLFVKVGRK-----FSLKTVLMLVDQMIQRIEFMHSRNFLHRDIKPDNFLMGGPKRSNKCYLIDLGLAKRYIDKFGKHIPYRENKNLTGTARYA
   .| |. .| ||.     |.  ..  .. |... .|..||....|||.||.| |.          ..| |||...             . . ||  | 
DLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-------------TTFCGTPWYM

SINTHVGIEQGR-RDDLESLGYVIMYFLRGILPWQNLKAEGKKDKYERIMEKKMQTPVEVLCKGFPTEFATYLQYCKNLRFEDKPDYSHCRQLFKQVMTR
.         |. . |  |.| ..  .| |  |..          ......| .                                 . .... .. ...
APEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP---------QMQMMFKKIG--------------------------------SPEAKDFIRKCLQK

N-----GWDYDFE-------WDWK
.     .    ..         | 
DPEKRPTA-EALQDEWDIKCHPWF
Kinase 23028.AA TTBKL 14-70 25 4.4e-14 44.02 In-house 1-60 (288) Show / Hide 
Range on Protein: 14-70
Range on HMM: 1-60/288
Sequence Identity: 25% (15 aa)

YKIVKKLGSGAFGEIFLAINRQNGEEYAVKVEEANS-RH-PQIM-FEAKLYNYLNNGSSS
..|||..|.|.||.......... ...|...|| |.  . ...| .|... . |....|.
WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSP
Kinase 23028.AA Worm6 14-53 25 4.2e-13 43.66 In-house 1-44 (279) Show / Hide 
Range on Protein: 14-53
Range on HMM: 1-44/279
Sequence Identity: 25% (11 aa)

YKIVKKLGSGAFGEIFLAINRQNGE--EYAVKVEE--ANSRHPQ
.|..||.|.|.|| .... ......  ..|.|.|   .|. ...
WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQM
Kinase 23028.AA TTBK 14-48 50 1.3e-10 33.72 In-house 1-36 (257) Show / Hide 
Range on Protein: 14-48
Range on HMM: 1-36/257
Sequence Identity: 50% (18 aa)

YKIVKKLGSGAFGEIFLAINRQNG-EEYAVKVEEAN
 |.||| | |.||||. | . .|  |. |.||| |.
WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVESAQ
Kinase 23028.AA TyrKc 14-298 18 1.6e-05 -133.13 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-298
Range on HMM: 1-280/280
Sequence Identity: 18% (59 aa)

YKIVKKLGSGAFGEIFLAINRQNGEEYAVKVEEANSRHPQIMFEAKLYNYL--NNGSSSESGLNNSISGTSSYSSSDKGIPRVYFCGQDQ------GYNI
 .  ||||.|||||..... .   .. |||.  ... .  .| ||..   |  ..                     .  .  .  | |..      .   
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHH---------------------PNIVRLYGVCTQQGRNFMYIEPLM

MVMDLL-GESLEDLFVKVGRKFSLKTVLMLVDQMIQRIEFMHSRNFLHRDIKPDNFLMGGPKRSNKCYLIDLGLAKRYIDK-----FGKHIPYRENKNLT
.|| .  . .| |   | ..|...|. |    |  .  |. ||.|. |||.   | | | ..    .   | ||..   |.      .. .  .| |.  
IVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGK

--GTARYASINTHVGIEQGRRDDLESL-GY------------VIMY--FLRGILPWQN-----LKAEGKKDKYERIMEKKMQTPVEVLCKG-----FPTE
     |  ..              |..  .            | |.  | .|  |. .     ....   . .|.... ..  . .  .        |.|
TMLPIRWMAP--------------ECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQ---EVIEYVKQGYRMPQPPNDY-PMSFVCCPDE

FATYLQYCKNLRFEDKPDYSHCRQLF
  .  . | .   || |  | ....|
MYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 23028.AA VRK 14-45 32 0.00023 10.38 In-house 1-37 (284) Show / Hide 
Range on Protein: 14-45
Range on HMM: 1-37/284
Sequence Identity: 32% (12 aa)

YKIVKKLGSGAFGEIFLA---INRQN--GEEYAVKVE
... |. |.| ||.|.||    .  .  .  | ||.|
WRLGKPIGQGGFGCIYLASPNTCKPCEKDAQYVVKIE
Kinase 23028.AA Pkinase_Tyr 14-32 47 0.000594 14.01 Pfam 1-19 (270) Show / Hide 
Range on Protein: 14-32
Range on HMM: 1-19/270
Sequence Identity: 47% (9 aa)

YKIVKKLGSGAFGEIFLAI
 .. ||||.|||||.....
ITFGKKLGEGAFGEVYKGT
Kinase 23028.AA Pkinase_Tyr 143-155 46 2.527253 1.72 Pfam 125-137 (270) Show / Hide 
Range on Protein: 143-155
Range on HMM: 125-137/270
Sequence Identity: 46% (6 aa)

EFMHSRNFLHRDI
|. .|.|. |||.
EYLESKNCIHRDL